I am always fascinated watching Zacks lectures. It always blows my mind how we humans are able to figure this all out. How!?!?! Its amazing and thank you for sharing!
Italian medical student here! I'm glad I found you on YT, you're such a life-saver. Thank you for sharing your passion for these subjects, you're amazing man! (and your staff too, of course)
Your videos are absolutely saving me so I can pass pathophysiology and pharmacology in my NP classes. After I watched your videos, every topic made sense to me. Thank you for what you do.
I recently cleared my post graduation, all the basics that u taught was like never been taught or studied my me.. Thank you.. You are just awesome.. Heartly gratitude 😊
Actually I've been struggling with Parkinson's drugs and mechanisms as I used to hate pharmacology the first medical year in college but this video definitely make it way too easier , I am really feeling grateful, thank you a lot ❤❤❤❤ you are the greatest 💪🏻
Amazing this video save me, I spend many days to read textbooks and watching my lectures and I feel so dumb but now this video is totally make sense to me and put everything I’ve read together, thank you so much 🎉
As always another great video. Wife recently diagnosed with Parkinson’s. Been doin a deep dive into high does of B1 (thiamine) for treatment. After adding it to the treatment made a huge improvement over the meds (Rytary $$$$$). Would love to see a deep dive into why/how this mechanism might work. Most doctors don’t know or haven’t heard of this treatment. Obviously no money to be made on a vitamin. Thanks again for you dedication.
Absolutely love your work and appreciate what you do, I am an avid watcher of your paid site while I’m in FNP school. I would like to mention one thing, please find some other marker or remove the tops before you begin and stop clicking them on and off. It happens right at your mic and it becomes very annoying and distracting from your lectures which are so very important and would be amazing with less distraction like the caps constantly screeching….thanks!
Hello, I admire your job well done, it is very helpful for all of us! I watch you regularly and learn new things! Thanks! I'm doing a doctorate! I am looking for a connection between impaired understanding of human language, more precisely decoding, in patients with Parkinson's syndrome! What can it be, and where does it come from? Help!!! Be healthy and happy 🙂
Great video! It answered almost all of my questions. The only question remaining is, why is it so important for Parkinson’s disease drugs to be giving at specific times with little to no goodwill time? Does it have to do with the effective time?
I remember voting for pharmacology videos many months ago. I don't want to complain but I relied heavily on you to passing anatomy and now that I'm in pharmacology I'm gonna need you to hurry up 😜 . We did Parkinson medications last week 😞
Very informative. Learnt a lot even as a geriatrics doctor. Perhaps include apomorphine in the drugs? Confess I love your explanation so much I don't want to go back to the books for that!
Hey guys,i have a question and i would appreciate any help. The cholinergic neurons ultimately have an inhibitory effect on the motor activity of both the direct and indirect pathways. In the video, Ninja Nerd mentions that a tremor arises from overlapping activity of the direct and indirect pathways. However, if both pathways reduce motor activity, it doesn't seem like there would be a contraction of the agonistic and antagonistic muscle, which is what would lead to a tremor. Do you understand what I mean? So do you know if I may have misunderstood something, or how else does tremor occur? Also, Rigor would be illogical if motor activity were reduced, but we do have Rigor, just like Tremor, in Parkinson's disease. Thank you! Best wishes from Germany
Hi, excellent video! single handedly getting students through medical school no doubt! I did just have a question: at 52:10 you said those dyskinesia side effects arose because you are causing too much stimulation of the indirect pathway, but since the indirect pathway inhibits unwanted motor movements, wouldn't INHIBITION rather than stimulation of this pathway pose problems? I really appreciate you answering:; thank you
A quick question...does ADR's in brain happens due to excess dopamine? as dopamine cannot cross BBB and if yes, then how does ADR's happens in mesolimbic pathway
Great question. Any drug that increases synthesis of dopamine, prevents breakdown of dopamine can be utilized in dopaminergic pathways in the brain i.e mesocortical or Mesolimbic pathway etc
I learned a lot from this lecture, great experience and hopefully I'm able to make full use out of it One request I have... Sir, can you make a video for haemorrhagic and ischemic stroke pathology??
You helped me so much with so many topics but most recently hematology - can you make some videos on the types of leukemias and lymphomas? thank you so much for what you do!
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You are remarkable, I have never met a teacher like you.
I am speechless at how gifted you are in teaching. We must protect this man.
From whom? no one hates him😭
I am always fascinated watching Zacks lectures. It always blows my mind how we humans are able to figure this all out. How!?!?! Its amazing and thank you for sharing!
Italian medical student here! I'm glad I found you on YT, you're such a life-saver. Thank you for sharing your passion for these subjects, you're amazing man! (and your staff too, of course)
Starting an assignment on PD meds for my pharmacology class today! SO perfect!😍
Your videos are absolutely saving me so I can pass pathophysiology and pharmacology in my NP classes. After I watched your videos, every topic made sense to me. Thank you for what you do.
You are Excellent. Great teacher. Thanks from retired RNBSN with Parkin sons. Still with thrist for knowledge to understand. Thanks.
I recently cleared my post graduation, all the basics that u taught was like never been taught or studied my me..
Thank you..
You are just awesome..
Heartly gratitude 😊
You have a gift and I am so grateful for your existence on this earth and time.
Kindly make videos on antidepressents and anxiolytics ...plz
please please continue making pharmacology videos ,as pharmacy student i find these so helpful
thank you for your effort
I love the way you you teach I think your are the bestest teacher in this whole world 🌍
I’m grateful for your existence, you do matter & we appreciate u
didnt watch this yet but without doubtes i know it will be a BANGER
Thank you Dr
I never bothered learning WHY we used COMT and MAO B inhibitors before this video, damn thank you!!
Actually I've been struggling with Parkinson's drugs and mechanisms as I used to hate pharmacology the first medical year in college but this video definitely make it way too easier , I am really feeling grateful, thank you a lot ❤❤❤❤ you are the greatest 💪🏻
You are amazing at teaching, can’t believe my luck at coming across your channel. Thank you for sharing your expertise 🎉 truly remarkable 🎉
I love your passion and teaching, always amazed. Thank you very much.
Amazing this video save me, I spend many days to read textbooks and watching my lectures and I feel so dumb but now this video is totally make sense to me and put everything I’ve read together, thank you so much 🎉
Your videos are amazing! Clears up so much information left out by professors! Thank you for everything you do.
Always so beneficial when learning complicated concepts.
You are my saver for any exam preparation
So helpful. Thank you! ❤
I love your memory and your passion! ROCK STAR!
As always another great video.
Wife recently diagnosed with Parkinson’s. Been doin a deep dive into high does of B1 (thiamine) for treatment. After adding it to the treatment made a huge improvement over the meds (Rytary $$$$$). Would love to see a deep dive into why/how this mechanism might work. Most doctors don’t know or haven’t heard of this treatment. Obviously no money to be made on a vitamin.
Thanks again for you dedication.
That would be a great topic to cover!
Be healthy sir 🙏 we really need you
You truly are the best teacher ever! Thank you for this video.
Absolutely love your work and appreciate what you do, I am an avid watcher of your paid site while I’m in FNP school. I would like to mention one thing, please find some other marker or remove the tops before you begin and stop clicking them on and off. It happens right at your mic and it becomes very annoying and distracting from your lectures which are so very important and would be amazing with less distraction like the caps constantly screeching….thanks!
God bless you in the ways you do not even imagine!
You are a saviour .Thank you zach🔥
very informative video, you are helping so many students and professionals
i love u man, u made it easy on me to understand the topics
Thanks a lot for the perfect lecture!
Love your passion for teaching! Thank you!
Love this❤❤❤❤Need more! Excellent Teacher.
Finally All concept clear 😌Salute to your Passion and Strength. Love from Odisha.
you are great God bless you the best teacher ever am medical student in east Africa Ethiopia
You are the best of all the time in saving med students life we are craving for more pharmacology
you are a great human being
Antiparkinson's drugs and hypnotics vids are on time, if only the antipsychotic drugs are on the list it would have been just geeat
Thank you so much for everything❤
Hello, I admire your job well done, it is very helpful for all of us! I watch you regularly and learn new things! Thanks!
I'm doing a doctorate! I am looking for a connection between impaired understanding of human language, more precisely decoding, in patients with Parkinson's syndrome! What can it be, and where does it come from?
Help!!!
Be healthy and happy 🙂
Great video! It answered almost all of my questions. The only question remaining is, why is it so important for Parkinson’s disease drugs to be giving at specific times with little to no goodwill time? Does it have to do with the effective time?
Extraordinarily well made video.
Thank you, Zach
I can't thank you enough for this video 🙏
You're just awesome ❤
Thank you so much ninja nerd❤ you're a life saver
Sir I appreciate your work
Thank you so much
A love from TANZANIA.......!
Great teaching process👍🏻👍🏻👍🏻👍🏻
I remember voting for pharmacology videos many months ago. I don't want to complain but I relied heavily on you to passing anatomy and now that I'm in pharmacology I'm gonna need you to hurry up 😜 . We did Parkinson medications last week 😞
you are just LEGENDARY
Great video, very informative!
Thank you for this video!
the best teacher ever🌹
Thank uuuuu best teacher ever
I used to follow You when the channel has some 70k so soproud that you ve reached the M
You deserve mooooore
Very informative. Learnt a lot even as a geriatrics doctor. Perhaps include apomorphine in the drugs? Confess I love your explanation so much I don't want to go back to the books for that!
Your amazing !! Love and prayers from India 😊
I comment for you before I watch the lesson because I’m sure you are great
Hey guys,i have a question and i would appreciate any help.
The cholinergic neurons ultimately have an inhibitory effect on the motor activity of both the direct and indirect pathways. In the video, Ninja Nerd mentions that a tremor arises from overlapping activity of the direct and indirect pathways. However, if both pathways reduce motor activity, it doesn't seem like there would be a contraction of the agonistic and antagonistic muscle, which is what would lead to a tremor. Do you understand what I mean?
So do you know if I may have misunderstood something, or how else does tremor occur? Also, Rigor would be illogical if motor activity were reduced, but we do have Rigor, just like Tremor, in Parkinson's disease.
Thank you! Best wishes from Germany
Omg thank you!! I take my PANCE in a few weeks and your videos are so good
The reason i will be a Pharmacist will be bc you exist! You are much loved in England
Guru dev, Thank you so much, Jarur, Murshidabad WB India🇮🇳.
Great quality
The best Ph of medicine
thank you so much sir, may god bless u
Hi, excellent video! single handedly getting students through medical school no doubt!
I did just have a question: at 52:10 you said those dyskinesia side effects arose because you are causing too much stimulation of the indirect pathway, but since the indirect pathway inhibits unwanted motor movements, wouldn't INHIBITION rather than stimulation of this pathway pose problems?
I really appreciate you answering:;
thank you
You are intelligent you go deep into it
Let this man open his university ❤
thank you for your help! I am grateful! 😇
You know Zach that your vids are kind of entertainment!
Thank you helping me with my pharma exam😭😭😭😭😭😭❤❤❤
we need more pharmacology videos
outstanding all the time best teacher❤
A great scientist ever❤
A quick question...does ADR's in brain happens due to excess dopamine? as dopamine cannot cross BBB and if yes, then how does ADR's happens in mesolimbic pathway
Great question. Any drug that increases synthesis of dopamine, prevents breakdown of dopamine can be utilized in dopaminergic pathways in the brain i.e mesocortical or Mesolimbic pathway etc
You are awesome teacher, Man... Thanks for everything
Thanks
thank u so much for this video zach 🥰
I really like these videos, hope you get more recognition
Excellent video.
Thank you so much!!
Thank you!
Nice vid! Now one about Huntington’s 😊
Love love your videos. Thank you
hoping and waiting that you could upload more videos relating to pharmacology
I learned a lot from this lecture, great experience and hopefully I'm able to make full use out of it
One request I have...
Sir, can you make a video for haemorrhagic and ischemic stroke pathology??
Just search up those topics along with "ninja nerd" on TH-cam. They've made great videos on these topics a while ago
great job!! Thank YOu!!
thanks a lot for the way of informations 😘😘😘😘😘😘
you are the best! god bless you
Please make a video on anyipsychotic and anyidepressants
Nice video. Helpful and informative
thanks you sir,,,please upload analgesic also ASAP🙏
You helped me so much with so many topics but most recently hematology - can you make some videos on the types of leukemias and lymphomas? thank you so much for what you do!
Great Work!
Record a lecture on Opioids...plz Zach
You are amazing and vibrating
Thank you for this lecture.please say us lecture about Multipe sclerosis
Thanks a lot for your work! What’s confusing to me is that i thought colinergic neurons were interneurons in the striatum
I love your videos. Definitely one of the best out there. Also, nice glasses 🤓
love you zachy
Really amazing ❤❤!!