Drugs for Hyperlipidemia

Official Ninja Nerd Website: ninjanerd.org
You can find the NOTES and ILLUSTRATIONS for this lecture on our website at:
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Ninja Nerds!
In this lecture Professor Zach Murphy will be presenting on Drugs for Hyperlipidemia. During this lecture we will start with reviewing the basic pathophysiology of Hyperlipidemia. After we review Hyperlipidemia Pathophysiology, we will be moving into the various drug categories that are used to treat Hyperlipidemia including: HMG CoA Reductase Inhibitors, Niacin, Fibrates, Bile Acid Sequestrants, Cholesterol Absorption Inhibitors, and PCSK9 Inhibitors. As always, we will be including 10 practice problems at the conclusion of this lecture to truly master this topic. We hope you enjoy this lecture and be sure to support us below!
Table of Contents:
0:00 Lab
0:07 Drugs for Hyperlipidemia Introduction
0:32 Pathophysiology of Hyperlipidemia
20:01 HMG-CoA Reductase Inhibitors
34:38 Niacin
46:30 Fibrates
57:32 Bile Acid Sequestrants
1:11:23 Cholesterol Absorption Inhibitors
1:18:35 PCSK-9 Inhibitors
1:23:57 Approach to Lipid Lowering Therapy
1:31:30 Combo Therapy
1:36:54 Drugs for Hyperlipidemia Practice Problems
1:43:24 Comment, Like, SUBSCRIBE!
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Pharmacology Source:
Whalen, Karen. Lippincott Illustrated Reviews: Pharmacology (Lippincott Illustrated Reviews Series). Wolters Kluwer Health. Kindle Edition.
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#ninjanerd #hyperlipidemia #cholesterol

[@Mandy-dw9wm]

You helped me through high school, and now you're helping me in med school. It's crazy how easy you make everything!

[@manuellactaotao5364]

🎉🎉🎉🎉🎉

[@zainab.thinks29]

Me too

[@kobbey21]

y'all know how computer science majors have that one indian guy on youtube that helps them. Zach is our guy that helps us. I'm visual learner and this helps a lot

[@user-ku8wl2zs7g]

My professor is there to fail me and this guy here is really trying to deliver the knowledge and save me! Much appreciated!

[@hemanginipanchal3362]

Hello Professor Zach, Thank you so much for making pharmacology concepts so easy to absorb. Your lectures are perfects ( not much length and covers all the important information). I am preparing for my Pharmacy exam and having a 6 years of gap after my B.Pharm and M.pharm. But, before I go through the book, I first watch your video which really helps me to understand and retain concepts much better. Thank you Thank you Thank you soo much, for all your help in getting my license. keep up the good work.

[@bdreamy1807]

Zach, thanks man! You can't imagine how you're helping patients. Could you please consider making more lectures on MICROBIOLOGY and Steroids?

[@nzioka_dm]

It would help a lot

[@sherwin7472]

I just want to say THANK YOU SO MUCH PROFESSOR ZACH! Just finished our exams and i got top 4 with the highest scores in my clinical pharmacy. Thank you for your help! 🙇🏻‍♂️🙇🏻‍♂️

[@maquesonafeti7111]

Words will fail me if I want to capture the details explanation you gave.
Thanks joss!!!

[@Asadvlogs08828]

Doctor please upload the pathophysiology of GI system

[@BoredT-Rex]

He already has

[@andriadefilippi4512]

thank you so much for breaking these down. sooooo incredibly helpful for pharmacology this semester. many thanks & blessings.

[@stellawolf8278]

Hello! Your lessons are invaluable... i am a student nurse in my second year in France and in the thick of things... you make everything so attainable ... easy to follow.. fun.. I have shared with all my current class and professors ... loving it! Many thanks!

[@magicwinx8237]

I really don’t know what kind of brain you have you are a genius man !!!❤️

[@nzioka_dm]

That is quite much to cover but with the questions at the end it gets better, much appreciated

[@souad_joubbane]

this is beyond perfection!!! you're making great doctors.

[@phils4634]

Hi Zach
I am only a garden variety pharmacist but really enjoy listening to you when I walk for a couple of hours each week . Thanks so much for great informative presentations that are a pleasure to listen to. Just sad you weren't around in the 80s when I went to Sydney Uni because I don't think I've learnt enough comparing to what I don't know and what I am learning from you 🧐😯Timea S.

[@Abdullah_DS]

I didn't find a good lecture on TH-cam explaining anti-malarial drugs, so hopefully you explain it Zach🙏

[@merajbegum5978]

kindly post all the pharmacology related lecturers you are really a gem for students of medical background!

[@yvonnevillalba7722]

Thank you for this fantastic lecture. Your notes are perfectly structured and thorough. You are the best.

[@hevarmhamad1971]

Thank you thank you thank you i passed my all exams with watching you thank you a lot🙏🏻🙏🏻♥️♥️

[@zhilahaghbin4766]

so glad found your channel, it is so much fun to listen to you, and how neat you draw and write and excellent communicator

[@evgeniyamiller4503]

Thank you for your outstanding work!! Your lectures have helped me a lot! You guys are very much appreciated!!

[@zhilahaghbin4766]

Thanks much, you should get the award for Prof of the century:) so talented

[@ajunaid1094]

Sir you are just amazingly amazing I just can't you just make all this so amazingly interesting. Allhamdulilah I found a best teacher like you . Thanku for your amazing lectures

[@desireegarza1802]

Thank you for explaining things so clearly!!!!!!

[@MedsInfoDrAzmIshaque]

Thank you indeed for your tremendous efforts

[@muhammadabbas5547]

Thank you so much for making everything so easy for us ❤

[@lizawindle4175]

SO great and understandable! THANK YOU

[@johntom2362]

Thank you Zach for this video. 🙇🏽‍♂️🙇🏽‍♂️
I appreciate

[@cazarilolsen4630]

As a patient with this condition I enjoyed this vid.

[@sirap93]

You are great! Thank you for helping ❤

[@physiokhankhan4729]

You are such a great teacher

[@queteimporta7049]

The best profesor ever!!!!

[@ChlebMniam]

Oh doc thanks for this piece of art

[@dr.amalmohamed7607]

Thank you proff I really get alot information from your vedios and well undratand God bless you always

[@nadaa1103]

Very useful video as always! Thank you from me and all my future patients

[@Asphaltracergamer]

Zach you are an absolute legend 👍

[@virtualmanny]

The best lecturer!

[@abobo3]

Thank you for this great effort

[@med8224]

Amazing, I can tell even before watching

[@rosepearlcourt]

Thank you so much Doc❤️

[@eghdhdno3570]

MORE MICROBIOLOGY LECTURES PLSSSSSS (esp fungi and parasites!!!) i passed my class thanks to you last year but this year is all microbiology and pathology and i need serious help please please

[@zsigzsag]

I had a total cholesterol of 279. Take Zetia 10mg daily, I did experience severe muscle pain when other statins were tried. (also levothyroxin but hours apart). No other health issues. Went to a whole food Vegan diet (almost a year now). Last check total cholesterol was 205, still high. My doctor said its genetics. Went down to eating once a day, made sure I dropped sugar as well I carefully watch it.. Would an additional med help like a "fibrate". Thank you so much for this video, I do understand a lot more!

[@sharminbala]

Very helpful Videos of Ninja Nerd. Very gratful to you! Thank you

[@jenniferbryant545]

Zach, your lectures are amazing! Thank you for continuing to film new content for us. Question - according to the ASCVD risk reduction guidelines from ACC updated in 2022, it is recommended to add bempedoic acid as the “next step” after PCSK9 mAb and ezetimibe and I’m curious why you haven’t added this drug option to this video. Is there a reason? (I haven’t been practicing while raising kids and I’m reviewing to jump back in the saddle so I may have missed something!) Thank you!

[@DrAvees]

Prof. Murphy! I reallyy appreciate your way of teaching. You can go more high

[@Md_Haseeb125]

Hello sir , u r an outstanding professor I have ever ur teaching is amazing
Please make more videos on pharmacology
Anesthesia

[@ZaWakingEagle]

Thanks for the upload!!!

[@99Valem]

just what i needed, thanks

[@user-zq4fe4mq8c]

So great, thank you!

[@JD-dl3px]

The test review at the end of each topic is really helpful, please do these for all your videos. Please bring back the ninja nerd icon for your merch? I will proudly wear that sweatshirt.:) to represent passing my classes because of your awesome teaching videos.

[@MadaraUchiha-vj3if]

THANK YOU SO MUCH SIR

[@SpenserLiam]

Youre the best, brotha! Your shoulders must be stacked in order to maintain that prolonged writing and drawing!

[@BB-yr9ie]

Does anyone who has taken or is taking Human physiology course have any recommendations on how to do well/ study advice etc.? I find it a very challenging course

[@jeevajothivimal972]

Really good and easy to understand the concept.. veey helpfull..😊

[@triclover]

Amazing ! Thank you always

[@Uuuunnnnmmm]

Thank you so much

[@deborahobatoke268]

I have a question concerning the bile acid sequestrants. If they decrease cholesterol and therefore increase the LDL receptors, wouldn't there also be an increase in HDL synthesis? Because low cholesterol leads to more increase in HDL

[@xenap1974]

Thanks for the lecture! What if the cause is genetic? Do the drugs that act in the GIT do any effect? Or just Statins, Niacin and PCSK9 Inhibitors? Can we have a lecture on what happens in familial hypercholesterolemia? Thanks

[@leonchikumba]

Thank you

[@ShivangiMishra14]

You are the absolute best ❤!!!!!!!!!!!

[@thatbossguy123]

Thank you!

[@muhammadbaloch4222]

Thank you ❤️🥹😭

[@harshgoswami8805]

Thank you so much sir, would you make video on Chromosome movements during mitosis please 🥺

[@yashshah4140]

You are the best!! Waiting for more videos!!

[@incrediblenature-creation-1338]

Happy birthday to all who Oct 29born !!!
Have a blessed anionted day.God bless you all!Me as well !

[@lightvictor1530]

thank you for sharing, can you do lecture on immunology?

[@gihad697]

thank you so much

[@asmaoushi3564]

You R the best

[@TusharMathapati.]

Thank you so much 💓

[@tanveerabdullah3297]

You are the best

[@topsraywang559]

前面机理对我很有帮助 讲的很细🎉

[@noam8819]

Thanks king!

[@neblak3104]

You're amazing!!

[@MedsInfoDrAzmIshaque]

Need more videos about different calss of meds

[@BerhanuDebabu]

Respect for you💪

[@ancarachieriu1646]

Mulțumim!

[@vaibhavbarfa3988]

Great

[@iagom12]

Helping me go through nursing school exams 🩺

[@eashaanwar9834]

Thanks ninja nerd😊

[@asmaabadawy9998]

You're super hero

[@estbrqabuadela3997]

You make it look like is super easy to answer therapy questions 😢

[@ziadahmed6198]

you are the best

[@mageshs448]

Hi sir, can you please tell me best topic in biotechnology for seminar? Next week we have seminar session, please suggest more than one topic

[@Drshivamyadav]

Love you from India

[@user-ro6ef7gd8i]

You're amazing 😁🌿

[@Die_Empty.]

Please put on playlist

[@georginahanna8344]

THANK YOUUUUUUUUU

[@elinaparkkonen517]

💗💗 💗
💗 💗 💗
💗 💗 💗
💗 💗💗 INJA TEAM: Thank you for being so kind!!! 😍

[@user-sp7dy3tz3q]

thank you i love you

[@BoredT-Rex]

Mmmwahh...magnifico

[@malek22395]

thanks

[@tristinroberts5598]

thanks :)

[@drstar1136]

Zack waiting for anti arrhythmic drugs+ heart failure & diuretics ❤️

[@vioricagherman9216]

super

[@favourchidiebube3967]

Teach me nerd!!!
❤❤

[@paymansadradin9192]

Best everrrrrrrr🖤🖤🖤📕❤️‍🔥

[@aslantabe1447]

can you do antidiabetic medications please??

[@muhammadahsan1668]

Plz make lecture on autocoids ...

[@facundoquinodoz8587]

zach i love u

[@HaniaNasirKhanHaniaNasir-zo4go]

Hey Respected Sir Zach Murphy ...... Hopefully uh will be doing great ......Sir Where are the Lectures Of Anaesthetics and CNS stimulants ......Sir Plz upload those lectures am extremely addictive towards ur lectures ND am unable to perceive anything from any other teacher or U-tube channel

[@FootballHome-nr7qv]

Yes sir please I humbly request u to upload videos on these topics asap we all do wait for ur boosting videos full of knowledge

[@dommydagger9320]

CORTICOSTEROIDS PLEASE