Metabolism | Electron Transport Chain: DETAILED | Part 1
ฝัง
- เผยแพร่เมื่อ 28 พ.ค. 2017
- Official Ninja Nerd Website: ninjanerd.org
Ninja Nerds!
In this lecture Professor Zach Murphy will present on part 1 of this three part series on the Electron Transport Chain (ETC). This will be a detailed discussion on the ETC and the regulatory steps used throughout this process. We hope you enjoy this lecture and be sure to support us below!
Join this channel to get access to perks:
/ @ninjanerdofficial
APPAREL |
We are switching merchandise suppliers.
DONATE
PATREON | / ninjanerdscience
PAYPAL | www.paypal.com/paypalme/ninja...
SOCIAL MEDIA
FACEBOOK | / ninjanerdlectures
INSTAGRAM | / ninjanerdlectures
TWITTER | / ninjanerdsci
@NinjaNerdSci
DISCORD | / discord
#ninjanerd #ElectronTransportChain #Metabolism
![รุ่นใหญ่ EP.2 บุกบ้าน เสรีพิศุทธ์ ระหว่าง บิ๊กต่อ กับ บิ๊กโจ๊ก อา รักใครมากกว่า ?? l [Nickynachat]](http://i.ytimg.com/vi/j2inUqhN__0/mqdefault.jpg)
4 years ago, and medical students up until today are still surviving with this. We can't thank you enough sir
Honestly
2024 and stillll
@@dysprosiumdead5078have a test in 2 days😂😂😂
@@tumelomoetsana6991 mine is tomorrow
And the Teacher of the decade award goes to...
century*
History*
@@kailashnathan3609
I
@@alaabdelhamed9114 il
I ii
L
@@Pro0osh can f
🎯 Key Takeaways for quick navigation:
00:17 🧬 *The electron transport chain occurs in the inner mitochondrial membrane, specifically in the folded structures called cristae.*
01:40 🔄 *The process starts with glycolysis, converting glucose to pyruvate, and further to acetyl coenzyme A, generating NADH and FADH2 in the Krebs cycle.*
04:53 ⚡ *NADH and FADH2, carrying high-energy electrons, enter the electron transport chain, starting with NADH being oxidized to NAD+.*
06:57 🔄 *Coenzyme Q (Q) receives electrons from NADH and is reduced to QH2, then passes electrons to complex 3 (cytochrome B) in the chain.*
10:57 ⚙️ *Complex 1 (NADH dehydrogenase) and Complex 2 (Succinate dehydrogenase) pass electrons down the chain, with Complex 1 pumping protons into the intermembrane space.*
14:03 🔄 *QH2 passes electrons to cytochrome B, pumping more protons, and then hands off electrons to cytochrome C, continuing the chain.*
18:07 🔗 *Cytochrome C transfers electrons to cytochrome oxidase (Complex 4), leading to the final step where oxygen is involved, forming water.*
22:46 🌬️ *Oxygen is the final electron acceptor in the electron transport chain, forming water when combined with electrons and protons.*
23:40 ⚡ *Energy released during electron transfer at complex 4 is used to pump protons across the inner mitochondrial membrane.*
27:34 🔄 *Protons are pumped out at Complex 1, Complex 3, and Complex 4, contributing to a higher proton concentration in the intermembrane space than the mitochondrial matrix.*
28:30 📊 *Proton concentration gradient across the inner mitochondrial membrane establishes a concentration gradient, a crucial aspect in ATP synthesis.*
28:57 🔄 *NADH produced in glycolysis needs a specific mechanism to enter mitochondria for electron transport, a topic to be covered in the next video.*
Made with HARPA AI
It's so sad that I only got to know u in the night of my exam!! u r soooooo sooooooooooooo soooooooooooooo amazing! and it's totally frustrating that the viewer's umber is so low, I rlly wish u all the luck from the bottom of my heart cuz u most defenetly deserve it! you are just AMAZING!
+Marwa Dante wow!!! Thank you so much for your super kind words they mean so much!!! I wish you the best of luck in your future endeavors!!!!
Thank you so much! Please spread the word about this channel. We really appreciate your support 👍
Thak yo best of luck to you too ^_^ and you will make it big! I'm sure of it cuz u deserve it
@@NinjaNerdOfficial It is amazing how the multiply levels of complexities of life points to a creator !
*God !*
Wow
I have to say, it took me some time to realize that the NADH gives one proton to FMN, but i was confused as to why it was FMNH2 and not FMNH since it's getting one proton and 2 electrons from NADH. And in the video he doesn't explain where he got the second proton from. I finally understood that the NADH actually combines with a proton from the matrix which has an abundance of protons. So it's NADH + H+ to FMN = FMNH2.
yes NADH, H
nice thanks for this :>
Thanks, this had me confused for a minute, too!
if so, where the proton that is being pumped out comes from:(? if we pass to protons on fmn
@@gosiascios6720 Hydronium ions in the mitochondrial matrix will give up their H+ proton, complex II also generates additional H+ protons which the other three will pump :)
You´re saving my academic life at this point
كل الكلام والوصف قليل بحقك حرفيا اعجز عن وصفك شكرا من القلب 🙏🤍
في الدقيقة 8:46 لماذا FMN اصبح FMNH2 على الرغم من انه اخذ الهيدروجين من NADH و ليس NADH2
BORN TO TEACH. PERIOD. Thank you a lot Sir, I nearly quit the understanding of ETC but you've made this topic the easiest one you could ever get. GOD will richly bless you.😍😍🥰
You know it's hella information when the ninja nerd needs a part 2 and 3...God save us all😂😂😂
You helped me with Immunology and now Biochemistry, my god what would I be without your videos...I always draw with you and now I can even explain the things myself! You are the best teacher and I will be thankfull forever...telling all my friends you exist
interesting that u are taking immunology before biochemistry haha
@@zzoldd I just like Immunology more than Biochem so I took the exam later :)
@@zzoldd I’m taking both at the same time bruhh
If you can teach all this stuff so well and so elegantly, and that too almost in no time, I can only imagine how much effort you put in to this! Thank you a lot! ❤️
The best explanations ever seen on ETC
I studying this for 3 years just for exam amd forgot it and read it again ..... Now I underdstood at peak level I wish that should have more viewers.... !!!!!!
Your videos have gotten me through my last undergrad semester between animal physiology and biochem. Literally thank you so much
I'm blown away by your explanation sir. I have urge to show this to my biochem teacher and scream she needs to explain it like this instead of just using smart board in the classroom. I swear you explain so clearly and you enjoy it too. I loved it sir, tha kyiu so much 😭❤🔥
You make it look simple!! You got a talent man! Thank you and the team !!
Thank you for uploading and creating such beautiful content! I'm so amazed and glad to find your channel.
You're officially me hero. Thanks for being a fantastic and fun teacher. If anyone can get me through grad school, it's YOU!
Thank you again, for wonderful, crystal clear and easy explanation. You are the best!
the best thing about your teaching is that it seems like 'the things were meant to happen that way', so easy explaination....I tell all of my friends to subscribe ur channel....thank u....Love from India
You make them ridiculously simple. thanks for your time and effort
"O.K. I'll take the potato" That gave me the laugh I needed right about now Haha!
as someone with adhd who finds it hard to concentrate in 2 hours lectures, i can't thank you enough for your incredibly well-made videos. you're helping so many future doctors, thank you Sir!
Most of the profs in my uni cannot teach. Thank you for your videos. They are so helpful!
"Okay, I'll take the potato"
- Oxygen, 2017
This man here saved my whole life we literally need this in almost every module in med school!!! Thank you🙏🙏
You are awesome. No one teaches biochemistry like that. Kudos! Keep going ahead👍.Thanks for sharing your knowledge. You deserve all the praise and glory.
Literally carrying me through Biochemistry... bless you good sir
I have no idea how you don't have more views on your channel! Your videos are amazing and extremely helpful!
I've watched countless videos and no one comes close to explaining the ETC as well as you do. Once I get those stacks, I will be sure to donate to your channel.
Literally a life saver . If all lecturers taught like you medschool would be a 100 times easier,
6 years later and you’re still saving the world. Truly not all superheroes wear capes. Some set up a TH-cam channel and teach millions of students biochemistry . Thank you ❤❤❤❤
i'm preppin for my licensure exam and I'm reviewing thru these videos. very detailed and very easy to understand. thank you!
we looooovvvvvve you man, I'm a medical student and can't imagine my second and third year how terrible they would be without you guys
Extremely well explicated, great job!
You've got yourself a new subscriber. This is great man, thanks!
I liked it before even watching it 😂
Best biochem videos on The internet! Thank you so much
Finally got this concept. Thanks man you're a legend👏🏻
👏👏👏 thanks man. Your working so hard for us
You are a GPA saver ...u saved me ....6 hours more to write my midsem ...thank you. ..I wish my biochemistry teacher was like u😢😢😢😢
i regret only coming across your channel this year. your channel would have helped me had a solid foundation of different pathways before id gone off to college. happy that i found u now tho great work!
you are a pure talent, thanks for your great efforts bro
Your videos are phenomenal --> saving my uni biochemistry grades! Thank you!
You're the GOAT! Getting me thru med school biochem thanks so much man :)
i cannot believe how AMAZING your videos are
Weirdly, this is the beeeeeeeeeeeeest teacher ever!! He knows how to transfer the information!!! We can't thank you enough sir
awsome lecture!!!!!!!!! never stop please
Thank you so much for the explanation. But I'm wondering where does the energy released from complex II go? Is it just dissipated as heat and lost to the surroundings? Or is there any physiological significance in this?
Very nice analysis sir
GOD BLESS YOU
You are legendary!
Truly a life saver!
I've never enjoyed cellular respiration but now..
It's so fun because of your way of explaining it. Thank you so much!
I have a degree in biochemistry from UC Berkeley. This is one of the best descriptions and elaborations of the ETC (OxPhos) I have ever seen. Kudos to you. And ... it shows NADH (and FAD) not NAD+ are critical. Also show the need for Fe (Iron).
I AM REALLY ENJOYING TO LEARN ,and the way you teach is superb ...u rock the ninja nerds
you are amazing, I understand everything now
Man you are a lifesaver!
YOU GOT ME THE MOMENT I SAW YOUR VISUAL DRAWINGS! IM OFFICIALLY PART OF YOUR STUDENT NOW!!.. Haha
15:07 whenever I hear complex names..
thanks for the great explanation !
You are really great
I didnt even understand when my teacher teaches
Thanks to you i will get good scores in metabolism
professor turn-ons: black markers ....
.
.
but man srsly...you a lifesaver..i just love your style so much.
I am dentistry student and I was not able to understand this subject but thanks to you I understood very well THANK YOU SO MUCH
wowwwwwww...amazing
js luv the way u explain everything .soo helpful👌👌👌
u r ma professor
for my hole semeter.
thank u sooooo much .
I watched all the videos.
I literally love this human
The comments here are years ago but the videos are still helpful till date. Thank you Murphy
Great educational content. Thank you!.
Thanks sir, as always it is so useful.
Amazing!
A LIVING LEGEND THANKYOU SIR
You are so great
Actually you are the best ever , you make it so easy for me
Absolutely amazing thank you sir
very helpful channel.
I have been watching your videos and their very very helpful to me in particular. You're doing a very good job, keep it up.
But I want to ask a question, how many moles of ATP can be generated from one molecule of maltose?
Thank you, I'll pass throught directly to second video.
you're amazing ZACH!!!!!
Thank you for the best explanation
Thank u for having u in our life
Thank you!! :D
Thank you for making student life easier 🙏
Thank you 🙏🏻🙏🏻🙏🏻
Thanks so much!!
Thank you so much, you are the best mann❤
hi does it have 2 Q complexes or does Q drop off electrons from one to III then comes back for the electrons from II ?
Is there a way to watch these videos in order from the beginning , in order to build upon knowledge? Thank you very much.
This is the next level
OMG WORDS CAN'T EXPLAIN THE GRATITUDE I HAVE FOR YOU !!
:')
Your video is helpful as usual
Just one problem complex II isn't supposed to have FMN as a component and it's not the reverse of krebs cycle reaction. It's the same and CoQ take the hydrogen directly from FADH2 it's mentioned like this in our book and in lippincott's too.
I’ve been interested in biochemistry since I watched your videos 😍😍☺️
I cant understand why this channel has so less views...There are so many fucking videos in you tube with no proper explanations...This video deserves a million views.....
Thanks a lot for such great videos.... I would like to request u to upload videos on bioenergetics and biological oxidation it would really helps me a lot
Wow this video was amazing! I’m actually so excited after watching it! I’m looking forward to starting Med school this September! (In 32 days 1st learning session)! Love from 🇬🇧 ! I’m heading to part 2 of this vid!!!
brooo please enjoy you last summer dont think about this
Professor Zarch, Thank you so much
The running animation was crazy! 8:19
Thnks lecturer understood very well
you are the best i love your teaching
great. continue. best wishes
awesome dada!!
keep up the good work dude
you are great man
your a genius i watch all your TH-cam videos you should put an interview up. Explaining your resume' for your teaching professional career.
This guy is the grown ben from never I have ever 💜💜best teacher ever
Great lecture! One question: What happens to the protons from FADH2 after they are picked up by FMN in complex 2?
This is only my own guess.. I think the protons might stay in the matrix, to maybe control the concentrations of protons in matrix and in intermembrane space.