It is sad that I got more out of this video than in 3 lectures from my university professor. Some people really should not teach, thank you for being someone who is reliably good at teaching.
It was barely mentioned at our medschool university (just randomly inbetween something else) and then it popped up multiple times on the exam where we were just supposed to memorize a random enzyme at a certain step etc. It is fair to say that the majority is up for credit test as the first midterm was just as bad. I wish they tested us in understanding rather than pointless memorization.
im sure after few years ninja nerd science is going to be one of the most effective medical videos on TH-cam, the way you explain things we cant forget.
I am a Biochemistry student from Nigeria and I have benefitted stupendously from your videos. I can't for the life of me fathom how you developed these teaching skills. Thanks so much. Please do more.
I never comment on videos on TH-cam but I have to just to say this guy is amazing. I was ready to quit my course after my metabolism lecture as it made me want to cry. I left my lecture halfway through and then the following day I found these videos, and not only did I understand it all, I actually really enjoyed it. Thank you so much!!!!
A little note to take at 17:17 very important correction... it's unfortunate we can not draw diagrams in the comment section but I hope this piece helps out .. 😆😂😂 Ribulose 5-phosphate is first epimerized to xylulose 5-phosphate. Transketolase catalyzes the transfer of a two-carbon fragment from a ketose donor to an aldose acceptor .In its first appearance in the pentose phosphate pathway, transketolase transfers C-1 and C-2 of xylulose 5-phosphate to ribose 5-phosphate, forming the seven-carbon product sedoheptulose 7-phosphate . The remaining three-carbon fragment from xylulose is glyceraldehyde 3-phosphate.
Don’t skip ads, or don’t skip the commercials, it’s they way also of earning money. At least we help them earn by not skipping the commercials, so they can make more videos in the future😍
I missed 2 weeks of lecture due to illness and this video cleared everything up!! So wonderfully organized!! Thanks to everyone in the comments making the small corrections too. You are all saving my grade
24:52 is where he explains the point of this pathway. Basically, there are two phases: (a) Oxidative Phase that can generate NADPH and Ribose-5-P. (b) Non-Oxidative Phase that makes Ribose-5-P without NADPH using glycolytic intermediates, and in reverse it can make glycolytic intermediates from Ribose-5-P. Note: Glyceraldehyde-3-P (GA3) in steps (5) & (7) can be funnelled into glycolysis or gluconeogenesis.
Thank you I am a Physician who diagnosed couple of patients with trasaldolase deficiency that was named after my name “Eyaid syndrome” . Your great video is the best one to explain the PPP Wish u the best
i will recommend ninja nerd to every single person seriously after taking any lecture from here u will totally be able to write in exam from ur own concept without even touching the book ..... u r going all the way best ninja keep going .
I am studying in first year in a medica school in Romania and these videos are really helping me to understand biochemistry:)) I am very grateful to the author of the videos
Just wanted to tell you that the first time I tried to study biochimestrey for my exam I got 56..than I discovered your videos, study with them, took the exam again and got 100!!!!thank you so so much!youre a m a z i n g ! I still hate biochimestrey though lol...😋
Having G6PD deficiency I am fascinated by your complete breakdown of what would happen in my body without the deficiency vs what is happening. Awesome video! Also, I get like...shamwow vibes or something from this...."then you get this, what can happen what does this give you!?" (feel like I'm gonna win the prize), but I think that's why you kept my attention so well-played sir!
Great stuff! I am going thru ur biochem videos just for fun. I remember, as a student long ago, loving the maze of the various metabolic pathways. For each pathway, there three points that must be made and emphasized. 1. The key, rate-limiting enzymes/reactions. 2. The main purpose or role of the pathway. What primary purpose does it serve? 3. The net energy balance (yield or cost) You described the pathway and what it is good for beautifully.
your videos are exactly a masterpiece!!! the intonation is perfect and it's your art that you make the audience to company you through the lesson keep going please!
Kudos to Professor Zach for consistently delivering top-notch educational content! The clear explanations and engaging presentation make learning complex topics a breeze. Keep up the fantastic work!
This is my first ever comment on TH-cam...never felt the need to do it...but sir ! ..i am so thankful to you ...you are a gem of a person ...THANKYOU SO MUCH! ...thank you for making studying easier
Love your videos! Just a tiny correction: Xylulose-5-Phosphate becomes GA3P and Ribose-5-Phosphate becomes Seduheptulose-7-Phosphate in the reaction catalysed by Transketolase.
You do a great job! Thank you for the clarity. I'm a very visual learner and would appreciate at the end of your videos, if you could step away so the audience can see the entire board. Thank you again!
I wanted to say thank you for the amazing video and teaching skills which you posses. I simply could NOT pass my biochemistry exam today. I had the shortest time ever to cover the topics and your videos helped me achieve the understanding in the best condensed and effect manner possible. Thank you to the Ninja Nerd Science/medicine. And to Zack Murphy. Thank you so much. You were a God send! God bless!
All your videos are so relevant as I study for my RDN exam. Thank you so much for putting all these together and explaining the details as well as the big picture.
Love your videos, very informative! Theres a slight error i feel you made though; its the xylulose -5-phosphate that donates the two carbons NOT the ribose-5-phosphate. The xylulose-5-phosphate is the donor ketose and the ribose-5-phosphate is the acceptor aldose which becomes glyceraldehyde-3-phosphate.
Dude love your videos, i study medicine in argentina but everything is so easy to understand that it doesn't matter being in english, awesome man , saved my year!
17:54 !!Just a tiny correction: Xylulose-5-Phosphate becomes GA3P and Ribose-5-Phosphate becomes Seduheptulose-7-Phosphate in the reaction catalysed by Transketolase. Also. I think transaldolase transfers only 1 carbon, instead of 3. (recommented what somebody else said in the comments section, to prevent people from getting confused) I LOVE YOUR VIDEOS!!!!
Thank you sooooo much. Mr.Ninja. Im on the first year of medical school. This makes me want to learn more, makes me feel like it good to know, it is super cool to understand. You just light up my world. Promise will be a good doctor.
I have my biochem lessons in french and im here watching this since its similair Hope i get more than 50% in the exam the day after tommorow PS: i like how i get recommended only the videos about the lessons i find hard and in right order well played TH-cam rly well played
In my biochemistry book the reactions are kinda different; After ribulose-5-P becomes Xilulose-5-P + Ribose-5-P then i have these reactions: >Xilulose-5-P reacts with the transketolase enzyme and TPP as a kofactor and gives -> glyceraldehyde-3-P + Glycoaldehyde radical. >Then Ribose-5-P reacts with the glyceraldehyde radical and gives-> sedoheptulose-7-P >Sedoheptulose-7-P reacts with the glyceraldehyde-3-P [transaldose enzyme] and gives-> eritroso-4-P + fructose-6-P. I don’t know why though...
This took my teacher 3 hours to explain and I still had no clue what he was talking about. Then Ninja Nerd comes and explains everything perfectly in 34 minutes 🥲
thank you so much , your all vieos are so helpful. easy to understand and remember. i watches in mt 1st year , i came back in 3rd year while i am prepairing for usmle ,coz ofcourse i had no doubt ,that your video will help me all over again .
love the way you teach it. makes SO much more sense and you're very clear and very calm when speaking and makes it so much easier to understand this. THANK YOU!
Love the text on the back of your shirt! You really are my Harper hero! 😂 For those who can’t relate, our reference for Biochemistry is a book by Harper and it’s just so hard to understand the concept just by reading the book alone. I just recently discovered your channel so now I’ll be here after every chapter in Harper. Thanks you your informative videos! Love from the Philippines 🇵🇭💕💕💕
Thank you for these videos, I still don't remember everything but, with these vids I start seeing some connections between the pathways that feel like maybe I understand
You are AMAZING!!! SO grateful for your videos, and I agree with the others - I'm learning more from your videos than from my biochem class. So wrong... Thank you, thank you, THANK YOU!🤗
It is sad that I got more out of this video than in 3 lectures from my university professor. Some people really should not teach, thank you for being someone who is reliably good at teaching.
your med school split the pentose phosphate pathway into 3 lectures
my med school put it in as a single slide in a different lecture
same here
L
It was barely mentioned at our medschool university (just randomly inbetween something else) and then it popped up multiple times on the exam where we were just supposed to memorize a random enzyme at a certain step etc. It is fair to say that the majority is up for credit test as the first midterm was just as bad. I wish they tested us in understanding rather than pointless memorization.
I got a 98 on my biochem exam because of this vid; keep doing what you're doing bro!
Tomorrow I will have mine
@@serva8334 good luck!
I concur
congrats! I hope I can do it.
@@biasedjedi4353 l
im sure after few years ninja nerd science is going to be one of the most effective medical videos on TH-cam, the way you explain things we cant forget.
U were right 😊
From 5yrs laters
You predicted well 👌🏽
I am a Biochemistry student from Nigeria and I have benefitted stupendously from your videos. I can't for the life of me fathom how you developed these teaching skills. Thanks so much. Please do more.
who would choose biochem as a major :"))))))
@@bensmainebensmaine7635Mind yo business.
people who have mental issues like us@@bensmainebensmaine7635
😊😊😊😊😊😊😊😊😊😊😊😊@@bensmainebensmaine7635
I never comment on videos on TH-cam but I have to just to say this guy is amazing. I was ready to quit my course after my metabolism lecture as it made me want to cry. I left my lecture halfway through and then the following day I found these videos, and not only did I understand it all, I actually really enjoyed it. Thank you so much!!!!
the same thing 💕
A little note to take at 17:17 very important correction...
it's unfortunate we can not draw diagrams in the comment section but I hope this piece helps out .. 😆😂😂
Ribulose 5-phosphate is first epimerized to xylulose 5-phosphate. Transketolase catalyzes the transfer of a two-carbon fragment from a ketose donor to an aldose acceptor .In its first appearance in the pentose phosphate pathway, transketolase transfers C-1 and C-2 of xylulose 5-phosphate to ribose 5-phosphate, forming the seven-carbon product sedoheptulose 7-phosphate . The remaining three-carbon fragment from xylulose is glyceraldehyde 3-phosphate.
Ninger Ned, you got to pin this comment.
📍📍📍
I had the same doubt
أنا كنت لسي هكتب دا برضو ميرسي لكومنت حضرتك
Thankkk uuuuuu
Can you explain same for trans aldolase
May god bless you.. Never stop making videos.. Really love ur channel.. U saved my life 😭😭
Don’t skip ads, or don’t skip the commercials, it’s they way also of earning money. At least we help them earn by not skipping the commercials, so they can make more videos in the future😍
I missed 2 weeks of lecture due to illness and this video cleared everything up!! So wonderfully organized!! Thanks to everyone in the comments making the small corrections too. You are all saving my grade
24:52 is where he explains the point of this pathway.
Basically, there are two phases:
(a) Oxidative Phase that can generate NADPH and Ribose-5-P.
(b) Non-Oxidative Phase that makes Ribose-5-P without NADPH using glycolytic intermediates, and in reverse it can make glycolytic intermediates from Ribose-5-P.
Note: Glyceraldehyde-3-P (GA3) in steps (5) & (7) can be funnelled into glycolysis or gluconeogenesis.
There’s no words can describe how much I’m grateful for you and your team ❤
Thank you
I am a Physician who diagnosed couple of patients with trasaldolase deficiency that was named after my name “Eyaid syndrome” . Your great video is the best one to explain the PPP
Wish u the best
Dr. Wafaa Eyaid
does giving nac (n acetyl cysteine)help patients with transaldolase def?
i will recommend ninja nerd to every single person seriously after taking any lecture from here u will totally be able to write in exam from ur own concept without even touching the book ..... u r going all the way best ninja keep going .
Exactly. I will also recommend everyone who asks me about biochem you tube lectures....!!!
I am studying in first year in a medica school in Romania and these videos are really helping me to understand biochemistry:)) I am very grateful to the author of the videos
Just wanted to tell you that the first time I tried to study biochimestrey for my exam I got 56..than I discovered your videos, study with them, took the exam again and got 100!!!!thank you so so much!youre a m a z i n g ! I still hate biochimestrey though lol...😋
😂😂😂
I remember my book in Medicine called "HARPER'S BIOCHEMISTRY". LOVE YOUR SHIRT!
You cannot imagine how much grateful I am for finding your channel! You did a great job here!
Me too !
Having G6PD deficiency I am fascinated by your complete breakdown of what would happen in my body without the deficiency vs what is happening. Awesome video!
Also, I get like...shamwow vibes or something from this...."then you get this, what can happen what does this give you!?" (feel like I'm gonna win the prize), but I think that's why you kept my attention so well-played sir!
Great stuff!
I am going thru ur biochem videos just for fun. I remember, as a student long ago, loving the maze of the various metabolic pathways. For each pathway, there three points that must be made and emphasized.
1. The key, rate-limiting enzymes/reactions.
2. The main purpose or role of the pathway. What primary purpose does it serve?
3. The net energy balance (yield or cost)
You described the pathway and what it is good for beautifully.
You deserve to have millions of views! YOU ARE THE BEST! KEEP UP THE GOOD WORK! Thank you very much. I wish my professors were like you...
Seriously...no one can beat you ❤
your videos are exactly a masterpiece!!! the intonation is perfect and it's your art that you make the audience to company you through the lesson keep going please!
Kudos to Professor Zach for consistently delivering top-notch educational content! The clear explanations and engaging presentation make learning complex topics a breeze. Keep up the fantastic work!
This is my first ever comment on TH-cam...never felt the need to do it...but sir ! ..i am so thankful to you ...you are a gem of a person ...THANKYOU SO MUCH! ...thank you for making studying easier
I’m new as a teacher, u make every single topic as so easy I’m really lucky to hear u. Best of luck
Thankyou for taking your time to make these videos,you have no idea how helpful they are.
I don't know how are you making these videos for free.
Thank you sooo much
Best video about this subject ever...
Love your videos! Just a tiny correction: Xylulose-5-Phosphate becomes GA3P and Ribose-5-Phosphate becomes Seduheptulose-7-Phosphate in the reaction catalysed by Transketolase.
Finally..i was looking if anyone wrote this comment😄
Exactly thanks for noting this
best videos! u first saved me with your anatomy videos, now with biochemistry videos!!! thank you from the bottom of my heart!
It's impossible to teach such concepts via 1 lecture. Your videos are incredible. Thank you
There're so many things this sucker is used for. Love it sir❤❤❤
Thank you you caused me to be confident at class and answer all questions God really bless you ❤❤❤❤
You do a great job! Thank you for the clarity. I'm a very visual learner and would appreciate at the end of your videos, if you could step away so the audience can see the entire board. Thank you again!
Members of the ninjanerd.org website get full access to pre and post-lecture whiteboard resources, as well as the lecture notes! - TG
Ninja I owe you all of my education please keep going on
Now I started to believe why ninjas are helpful to us , you are our ninja Hattori 😍...
I've an exam tomorrow and I dunno how I'm storing all this in my brain 😭
U good now bro ?
I wanted to say thank you for the amazing video and teaching skills which you posses. I simply could NOT pass my biochemistry exam today. I had the shortest time ever to cover the topics and your videos helped me achieve the understanding in the best condensed and effect manner possible. Thank you to the Ninja Nerd Science/medicine. And to Zack Murphy. Thank you so much. You were a God send! God bless!
All your videos are so relevant as I study for my RDN exam. Thank you so much for putting all these together and explaining the details as well as the big picture.
Saved my life and thousands of dollars of my tuition. Thank you prof!!
Waah ninja beta waah
Kamal kr Diya tune .tum jio hazaro saal
this is amazing! This gave me a clear understanding of this pathway. God bless!
+Shibani Thyaga rajan So happy the ninja nerd team could help you!
@@NinjaNerdOfficial in italiano
You and AK lectures are spectacular!
Will do my best to support you bud, keep up the great work.
thank you for all your videos you have helped me more then any professor or TA ever will!
YESSSS IM SO HAPPY I FOUND THE VIDEO EVEN BEFORE I START THE VIDEO!!
If biochemistry was a person it would have been you cause you really make biochem look easy😮 thank you so much prof
I love this channel for making my MBBS life easy...its my dream to meet you Teacher❤️
Love your videos, very informative! Theres a slight error i feel you made though; its the xylulose -5-phosphate that donates the two carbons NOT the ribose-5-phosphate. The xylulose-5-phosphate is the donor ketose and the ribose-5-phosphate is the acceptor aldose which becomes glyceraldehyde-3-phosphate.
+Shiru Nugi yes you are correct sorry for that mistake!
i have also confusion plzz..correct it ...show me some diagramtic view of this
Also product formed is sedoheptulose, not seduloheptose
That's true
Thanks for accepting your mistake💙💙💙💙
@@ysmusujit 7Psedoheptulose to be precise
You are a very great doctor , I have understood biochemistry very much even though I am an Arabic student I do understand you 🇾🇪💜💜💜🇾🇪
I got 96 in biochem special paper only because of you sir. Thank you so much for all the hard work that you do❤
Just a busy day of being a Ninjanerd🌟
Your lectures are truly life-saving !!
Yeah, ofcourse it is great, I mean zach is teaching us🤩🤩🤩🤩
He is on next level
Dude love your videos, i study medicine in argentina but everything is so easy to understand that it doesn't matter being in english, awesome man , saved my year!
The best ever teacher in d universe.....lots of love zack❤
17:54
!!Just a tiny correction: Xylulose-5-Phosphate becomes GA3P and Ribose-5-Phosphate becomes Seduheptulose-7-Phosphate in the reaction catalysed by Transketolase. Also. I think transaldolase transfers only 1 carbon, instead of 3.
(recommented what somebody else said in the comments section, to prevent people from getting confused)
I LOVE YOUR VIDEOS!!!!
Just cant express in words how helpful your vedio are. They have helped me a lot in building concepts and then going into detail of each concept.
Thank you Ninja nerd for helping us all Med students...
Thank you sooooo much. Mr.Ninja. Im on the first year of medical school. This makes me want to learn more, makes me feel like it good to know, it is super cool to understand. You just light up my world. Promise will be a good doctor.
Thank you.. god bless you for adding this series on TH-cam.
I have my biochem lessons in french and im here watching this since its similair
Hope i get more than 50% in the exam the day after tommorow
PS: i like how i get recommended only the videos about the lessons i find hard and in right order well played TH-cam rly well played
Thanks Ninja Nerd you have made my learning easier you are the best💪💪teacher in this earth as per my view
In my biochemistry book the reactions are kinda different;
After ribulose-5-P becomes Xilulose-5-P + Ribose-5-P then i have these reactions:
>Xilulose-5-P reacts with the transketolase enzyme and TPP as a kofactor and gives -> glyceraldehyde-3-P + Glycoaldehyde radical.
>Then Ribose-5-P reacts with the glyceraldehyde radical and gives-> sedoheptulose-7-P
>Sedoheptulose-7-P reacts with the glyceraldehyde-3-P [transaldose enzyme] and gives-> eritroso-4-P + fructose-6-P.
I don’t know why though...
Great! Wouldnt know what to do without all these videos
If I get high mark from biochemistry tomorrow, it will be with your help. Thank you for understandable videos!
did you get that high mark?
Gunel Aslanova did you get
@@rayaneb5186 he died
Gunel Aslanova Rest In Peace.
LOL
You are the best of bests doctor I have ever seen
The entire world is carried by people like this guy
AMAAZING EXPLANATION!! thankyou so much for making biochemistry so interesting!!!
You are really saving my biochemistry grade!!
You cleared all my doubts. Thanks a lot for making such an informative video (From Uttrakhand, India)
great great great. Med school would be much harder without u
Thank you for making all these very helpful videos. They’ve been life saving for me
hey Sir... a lots of love from Pakistan😍😍 you r just doing an amazing work... thanks alot for our help in studies😍😍 stay blessed😇
May god bless you.. Never stop making videos.. Really love ur channel.. U saved my life 😭😭
This took my teacher 3 hours to explain and I still had no clue what he was talking about. Then Ninja Nerd comes and explains everything perfectly in 34 minutes 🥲
Huge fan of nerd ninja❤️❤️
wow, the skill to memorize and explain the subject in these videos is awesome :O
This guy is so f*****g awesome. Besides, his accent is really cool..
your videos make metabolism look less overwhelming and more understandable. youre amazinggggggg thank u!!!!!!!!!!!!
+supercalified that's awesome! I'm so happy that we were able to help!
thank you so much , your all vieos are so helpful. easy to understand and remember. i watches in mt 1st year , i came back in 3rd year while i am prepairing for usmle ,coz ofcourse i had no doubt ,that your video will help me all over again .
Grateful is an understatement! Thank you for making these!!
thank you, I did not understand anything after watching my uni lecture, but now it makes perfect sense!
Thanks dr.zach for your effort , hope you get the fruits of it ❤
Dude honestly you're my hero God bless you 😭💗
Highly effective method of teaching
I really cannot appreciate you enough you're way too good buh ,Thank you prof.
Watching to gain more understanding and prepare for my exam on Wednesday! Thank you!!
it helped so much. i had a bias towards biochem before this video. thanks from Turkey
This is so making me pass my biochem exam tomorrow morning... Thanks
Fantastic young scientist. Congratulations.
I could kiss this guy rn😭♥️🔥 he's really good in these stuff
love the way you teach it. makes SO much more sense and you're very clear and very calm when speaking and makes it so much easier to understand this. THANK YOU!
Love the text on the back of your shirt! You really are my Harper hero! 😂
For those who can’t relate, our reference for Biochemistry is a book by Harper and it’s just so hard to understand the concept just by reading the book alone. I just recently discovered your channel so now I’ll be here after every chapter in Harper. Thanks you your informative videos! Love from the Philippines 🇵🇭💕💕💕
True harper really difficult to understand rather than lippincott
But he is the best teacher
Your videos sir they educate me more than any lecture 🙏🙏🙏 I really appreciate
Thank you for these videos, I still don't remember everything but, with these vids I start seeing some connections between the pathways that feel like maybe I understand
2 years old video and it’s still saving lives! Thank you, that MUDr. in front of my name is partly gonna be there because of you ❤️❤️
Only needed 24 mins to understand this....kudos to uh harpers heroes
You are blessing us with your videos sir, i literally had no idea to learn biochemistry, thank you lotsssss
You're always the best.
My ninja nerd . please! Keep on making more videos.
Congratulations
You're such a talented lecturer
I'm a huge fan of Ninja Nerd Science Videos! They are the best!
We love your support!!
Ninja Nerd Science I hope I can support your work ( by God's will )even more soon! It's amazing!
A lot of thanks for conceptual lectures May you live long
the best teacher ever
Sir thank you for making it understand so clearly.
You are AMAZING!!! SO grateful for your videos, and I agree with the others - I'm learning more from your videos than from my biochem class. So wrong... Thank you, thank you, THANK YOU!🤗