'Age-reversing' supplements: What NMN, TMG and berberine did for us
ฝัง
- เผยแพร่เมื่อ 7 มิ.ย. 2024
- In this week's video I share the early results of taking NMN, TMG and berberine together with my parents for one month - and whether we intend to keep going with this anti-aging regime, recommended by Dr Elena Seranova of NMN Bio.
We also discuss safety, and the powerful effects of taking this as a supplements combo, with berberine one of the most exciting natural solutions to supporting blood sugar levels.
#agereversal #antiaging #nmn
Subscribe to my channel here th-cam.com/users/TheHonestCh...
Find out more about NMN Bio's supplements, with a 10% discount included using this link: nmnbio.co.uk/discount/ClareJ
Discount code is ClareJ
NR alternative to NMN, TruNiagen amzn.to/3IfAaD9
My first interview with Dr Elena • Is NMN the 'longevity ...
FURTHER READING
The Glucose Revolution by Jesse Inchauspe amzn.to/3XEXVKF
Why We Get Sick by Benjamin Bikman amzn.to/3EgaoNV
Healthline articles on berberine's potential www.healthline.com/nutrition/... and NMN www.healthline.com/health/nmn...
You can find links and, where possible, discount codes for some of my favourite anti-aging and beauty products at go.shopmy.us/TheHonestChannel
I use affiliate links on this channel which means if you choose to buy a product using one of my links I receive a small commission - thank you! : )
This video is not sponsored. You can find my commercial policy here www.youtube.com/@TheHonestCha...
TIMESTAMPS
00:00 Intro
02:23 Why combine NMN with TMG and berberine?
06:38 Insulin resistance and age-related disease
12:12 NMN safety
18:29 What kind of results can you expect?
23:35 Our experience
Connect with me on social media:
/ honestclare
/ clares_j
/ honestclare
Edited by David at www.redfacilities.com
Disclaimer: This video and all content on this channel is for informational purposes only and is not intended as medical advice and should not be treated as a substitute for medical advice. - แนวปฏิบัติและการใช้ชีวิต
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I’ve been taking nmn 450mg for a month and I noticed a spike in my energy straight away, work outs are much more enjoyable, deep sleep and dreams, skin is noticeably softer (I am 54)… went to a function with friends and family recently and two people asked what I was doing as I look younger! So I am hooked, I believe incorporating daily exercise and good nutrition is part of this as they help to generate the effects even more. The Pulse is a good Chanel to follow on this subject.
Thanks so much for sharing this. It’s great to hear. I’ll follow The Pulse.
Oh and thanks so much, I enjoy your channel and find the info you provide really helpful ☺️
Do you also take TMG with your NMN ?
@@nicholablakely2832 is ur 🐈🐈🐈🐈 tighter with nmn
Absolutely bang on with exercise and healthy diet we have to remember that the benefit to our gut and body health is through fermented foods. Has been the Asian way for centuries
I have had bought Berberine and lost since then I taking them a few pounds ! Very pleased about it ! Thank you :)👍👍🌹🌹
I watch the other channels too, and I think you're the most articulate 🙏
That's kind of you to say, thanks.
Another great interview! Thank you Clare
Your timestamps really accentuate your nice videos! 👍
Thanks very much for this wonderful information ❤❤❤
Thanks you for sharing all this info.
During the lockdowns I fasted, went paleo and rapidly lost 22 kg going from hypertensive pre diabetes to perfect. A daily one hour walk to and from the gym was also helpful
Congrats.
I add AKG and creatine as well. At 70, the berberine is better for me with breakfast and dinner, but your supplement regime is sound and gets desired results.
Thanks for doing this video dear.
This regimen sounds great ! I am on a low budget so I use Nicotinic acid instead of NMN. Dr. Stanfield says that NMN and NR are quickly converted to Nicotinic acid after ingestion, so Dr. Stanfield uses 51mg Nicotinic acid instead of NMN.
Exercise I do now -
(To Raise Blood Oxygen, drop blood sugar, strengthen legs, arms and back) :
One or Two Minute Exercise Every Hour.
Sit on side of bed holding a small 5# weight in each hand at head level.
Stand, pushing weights up and inhaling through nose.
Sit down, dropping weights back to original position.
While moving down, with mouth closed, blow hard and release air on way down.
The back pressure on the way down increases oxygen transfer to blood.
VO5 will increase.
Continue exercise set for 2 minutes.
Do one set per hour. This has been shown to drop blood sugar spike so do extra sets after eating carbohydrates.
Varation: Hold weights down. While standing up, pull weights up under arm pits to tone biceps.
Thanks for sharing your experience!
Very good presentation, keep it up!
Thank you!
I like supplements, but EVERYONE should read "Fast and grow young". Our bodies are incredible miraculous creations with the ability to heal itself! All of todays "Dis-eases" are created by our diet. Our food lacks the nutrition it once had, and even 'organic food' has toxins from the soil. Fasting has long been doen throughout many cultures, and even animals instinctively 'fast' when they're sick. The book is fabulous and very eye opening.
Thanks for the tip.
Pppppppppppp
100% Amen. God tells us to Fast
Tell that to a potent virus…
@@PierreDybman ANY disease! You’re trying to open a whole other discussion. But yes, our bodies are designed to fight any ailment. Any signs of infection, such as runny nose, fever, cough, etc - they’re all SYMPTOMS of our bodies fight.
The problem today is that most people will run to the drugstore to get whatever remedy they can, instead of realizing that our body NEEDS the fever, it needs the getting rid of phlegm!
If dogs or cats, or any other animals get sick, they don’t eat! The body is naturally designed to go into fasting mode, so it can use all its resources to fight whatever disease.
Digestion takes up the most energy, so if we constantly feed our bodies, it takes away resources from this fight.
I referenced a book in my original response that I feel everyone should read. There is so much research and information on this subject … one only has to want to learn.
God bless 🙏🏼
great video! good point! Thank you!
The tiredness is exactly how you are supposed to feel at night. It means that your circadian rhythm has been reset. Awake during the day and sleepy and ready for bed come night time. I had a similar experience going fully carnivore. Great sleeps and fully awake as soon as my alarm went off and I was ready to go for the day.
Exactly!!! I was just going to post about this! People need to get realigned with our bodies and with nature. Also screen time before bedtime that she describes is terrible practice. It is SO important to take sleep seriously for health.
Thanks for introducing Dr Seranova, she has a wonderful ability to explain things precisely and clearly. I know NMN works because at first I took it at night and had the worst sleeps with a hyperactive mind ! Although at the same time my ability to absorb information dramatically increased. Now it's the first thing to take when I wake up before I exercise. The mind does remain clearer and more grounded. I've slowly come to regard carbs as the enemy, in some ways a poison, and here is confirmation that Keto with a lot of low carb veg is the way ahead. Cycling is a good idea, I have found the effects diminishing although maybe I'm just getting used to it.
Thanks for sharing your experience!
I love your videos!
Can you talk about "Nira PRO laser" only sold in England.
And "AMIRO" skin device.
Thanks!
Great video (as always) are you still on the supplements? An update would be fantastic!!
I still take NMN and am working towards doing an update in October. I dropped the TMG and berberine but then reintroduced TMG recently. Sorry for the delay in doing an update. We have had a couple of health setbacks - nothing major but we wanted to get the conditions right for testing our NAD levels properly.
Oh dear...I've been taking nmn for a about a month now during dinner 😳😳 I've been confused as to why I can't sleep at night. Literally an hour ago my friend asked me how my sleep has been and i said i have to take sleeping pills to even sleep a few hours. Ive always slept 9 hours a night. THANK YOU for this interview ❤️💛💕!!
Glad it helped!
Take it before breakfast or lunch at the latest. I treat it like caffeine in that respect.
@noutram1000 thank you ❣️❣️ I will :)))
I subbed, you asked great questions. Thank you !
Welcome - and thank you!
This video caught my attention because these are 3 out of the 4 supplements I take. The fourth is Cod Liver Oil.
Omega 3 is really important so that's a smart choice. I try to eat a lot of fish and also eat flaxseed daily.
I also take a low dose multivitamin/mineral tablet for the water solubles and Omega3 for the fat solubles.
NMN and NR are one phosphate molecule away from being identical. They’re both good folks
DrBeen did a recent podcast on Berberine- very in-depth.
Thank you for this fascinating and informative video! :) I'm wondering if you take a B vitamins complex, in addition to NMN? Is it fine to take niacin in addition to NMN? I have been taking Seeking Health's B-Minus Complex which contains 50 mg niacin but I don't know if that's compatible with NMN. All best wishes from Brighton ^_^
I'm reading about taurine, carnosine and jiaogulan for anti aging!
Very useful information especially when there are so many doctors promoting their supplements & diets! Hard to know which is best & right for one or what may be just hype. Thank you for investigative reporting! PS. Maybe your father may want to try the red light therapy on his feet for his arthritis to see if it may help as well?
Thanks Eileen. There is a lot of conflicting information out there at the moment, that's for sure! That's why I usually position myself somewhere in the middle of it all!!
Moringa is a godsend for treating arthritis.
thank you for another interesting video:)
Thanks for watching!
In March 2022, I decided that I was sick of being 16st. I did these things
1. Cut out sugar
2. Cut out carbs
3. Began a carnivore OMAD LIFESTYLE!!!!!! This is not a diet it is a life choice.
I am now a healthy 10st. ( Though BMI said I should be 7.5st. Ermmmm no way I would look terrible🥹)
I take NMN and TMG as-well as other supplements. At 60 I feel better than I did at 30. I have energy confidence and a new zest for life. PS Love the channel ❤
Is NMN beneficial on its own ? ie without the TMG ?
@@snowyowl6892 Great question. TBH I do not know if TMG makes a difference . It’s my understanding that the NMN will eventually work but TMG activates it and specs up the process. I definitely look and feel better, but how much if this do I contribute to NMN or living a different lifestyle????? It’s the same with all supplements I think. Only if we stop will we know if they did any good. Hope this helps.
@@snowyowl6892 Taking TMG/betaine along with NMN (or NR) helps with healthy methylation in the body -- it replenishes the methyl groups, since boosting NAD+ drains methyl groups, which can affect various biological functions. Studies also suggest that TMG may help reduce higher levels of homocysteine that can harden arteries, help manage fatty liver, help with insulin resistance, and with managing symptoms of anxiety and depression. The recommendation is to take equal parts TMG and NMN/NR.
@@C2C.
thanks .. appreciated 🤗
I was in bad health and overweight about 6 years ago. Sleep Apnoea and Acid Reflux. I was about 58 then. I felt consistently terrible. After some research, I changed to a Keto lifestyle. I shed the excess weight easily and never felt hungry on one meal a day. Sleep Apnoea and Acid Reflux gone. However, I think those things caused damage that I will have live with. I would urge everyone to adopt a healthy Keto lifestyle. Don't wait to get overweight and sick (insulin resistance). Prevention is best.
I feel much better, don’t need an Afternoon nap any more, more stamina but I do notice that I’m NOT sleeping as well and I’m only taking 250 mgs
I’ve been keto/ carnivore for ten years. Now 60 yrs young I feel fantastic. So much energy and cleared ALL my health issues . Stopped menopausal symptoms within months x
Margaret, can yo tell me any more details I am turning 60 this year and I started on a menopause patch .. I does help fight hot flashes. But I'd rather not be on them
Could you pleases interview Dr William Li EatTo Beat disease
I've been taking almost all those products for 6 months or more by ProHealth Longevity from California USA.
Hello, have you looked into Gary Brecka and the 10x genetics testing??
I tell people to shop the perimeter of the supermarket where the coolers of fresh food is kept. I also love my bulletproof coffee with grass fed butter
Same here.
Clare, with all this talk about blood glucose levels, have you considered wearing a continuous glucose monitor for a few weeks to *actually* track it? There are several on the market. Levels comes to mind. Zoe offers one as well if you agree to be in their study/ies.
I just think, rather than say you “feel” like your blood glucose is this or that, it would be more convincing if you *know.*
Yes, that’s a good shout
She is riding on the coattails of Sinclair while selling the supplements he recommends. Berberine is a non script alternative to Sinclair's darling, metformin.
Please ask dr Helena what are the 20 supplements she takes daily, thank you
I’ve been taking NMN for about three weeks and the first week was terrible. No energy, tired, sluggish- week three it’s finally got better! I feel rested in the morning, got energy during the day and im not wiped out after the day at night. It’s not the big burst I keep hearing about more a steady and consistent energy.
That's really interesting because I felt tired for the first few weeks too and that's resolved. I do think I have more energy overall - just as well as I really need it right now!
@@ranghashalatr142 NMN Bio and others ship internationally
@@thehonestchannel
HERXHEIMER reaction ✅
@@snowyowl6892... are you sure it's a reaction because I'm about to send my NMN back to the company, I feel horrible taking it for about a week now at 150 mgs?
I took NMN for almost a year waiting for an effect and felt nothing but more fatigue. I’m a healthy person so maybe it isn’t necessary.
I subscribed. I’m 10 yrs post menopausal and wondering if these supplements would be beneficial to bone density health?
Thanks for subscribing! This is a good question. I don’t have an answer but I will return to this subject on the channel and try to find out
Thanks for the info! I've recently come across Pycnogenol and am starting to take it. I've read some amazing benefits, like it increases hyaluronic acid levels in the skin up to 40%! It also helps with blood circulation. Keeping the blood vessels on the face healthy and living is important to aging gracefully.
What brand do you take?🥺
Interesting! Thanks for sharing this.
@@pineapple365 I've been taking the Now brand 100 mgs once a day, it also contains AMLA. I take it with arginine and ornithine upon awakening. A&O seem to burn fat for me. I'm on day 3. No side effects and I can tolerate taking it on an empty stomach.
@@melelle25 😇
@@pineapple365 BTW, The Ordinary has a 5% Pycnogenol topical. I've been using it for a couple of days. I don't really like how it feels on my face but I shall persevere.
In 1982 Pearson & Shaw in "Life Extension, A practical scientific approach" suggested caution in abruptly stopping megadoses of water soluble vitamins because of the potential of causing symptoms of vitamin deficiency if cells and tissues acclimated to high levels of vitamins are suddenly deprived of them. For this reason I doubt that "cycling" a water soluble co-enzyme like NMN is a good idea, at least not without a gradual taper off the dosage over a period of two or three weeks. For the same reasons Dr. Seranova recommends ramping up dosage when starting a new supplement, when quitting I think it advisable to ramp down the dosage over time as well. Cells seek to maintain Homeostasis, and abrupt changes mess with that.
You had me at vivid dreams
Would love any updates on your NMN journey!
I was planning to do something on my supplement stack in the summer so I’ll be sure to update. I’ve done a blood test to measure my current NAD levels and will do another after three months to see if taking NMN has increased it.
@@thehonestchannel Thanks for getting back to me Clare! I actually just today sent off my blood work for my NAD levels and can't wait to see what it says, I'm not sure what brand I will go with for NMN once I find out. I see the brand that you use but was also looking at DO NOT AGE which is where I got my kit from.
@@bigthingshappenin I started using DoNotAge NMN powder recently because they sent me a sample. So far so good.
@@thehonestchannel good to know! Thanks!
With so much talk about ketogenic and especially carnivore diets, I'm curious how this impacts the microbiome. I can't imagine one getting much resistant starch from a meat heavy diet but I'd love to hear an expert opinion on this.
I feel like potatoes shouldn't be a problem. But there are a lot of GMO potatoes, and with all the big farms and year round growing, the soil may no longer have the nutrients. And even organic potatoes, people peel them! I always leave the peel on mine.
There are so many supplements on the market so it can be quite confusing to know the ones that actually work. My friend was on supplements, a liquid to be precise, from a company called Fountain. I remember that it was quite expensive but looking at her I could actually see that it was making her skin glow. I believe that once you start on it you may have to continue in order to maintain the youthful skin.
There seems to be a new wonder supplement on the market with each passing day!
Maybe you could ask someone to give their option that does not aim to make a financial gain from selling their own product, an unbiased review .
I want to contact your guests basically see if help stroke recovery with supplements
Please can you discuss the role of NMN in rescuing female fertility on the next one? I know there's not much research into this area as yet, but despite the impact on reversing ageing on mouse fertility, it's being ignored atm. If men had menopause I'm sure it would be a different story! I'm taking NMN in the hope it reverses menopause temporarily and boosts my egg health. I'm also taking tmg and several other fertility boosters. I'm on a low carb diet too to reverse insulin resistance.
Btw are you aware of the FDA ban on NMN as a supplement in the USA? Apparently it's being withdrawn from USA shelves on March 13th and recategorised as a drug. Not sure what that means for NMN takers in the UK as yet despite reassurances from various companies. I'm following a GP who's wife had her menopause reversed on NMN. The current research shows the ideal dose of NMN is 600mg daily and powder is usually cheaper than capsules. You can Google the info on dosage/trials etc. The info is on TH-cam too. I also follow a channel called My NMN Experiment which posts lots of NMN studies that you might find useful. 250mg seems a very low dose to me but as you know it is an expensive supplement. You might want to add Apigenin or dried parsley or celery seed to your protocols to lower your CD38 levels to get the most from your NMN (CD38 increases with age and it lowers NAD). I hope it helps your parents. My dad has prostate cancer and I had a thyroid issue myself that I healed myself whilst reducing thyroxine, against medical advice....gradually! Not suggesting anyone should follow my example, but it can be done if you heal your body.
That ban on the sale of NMN might be specific to Dr. Sinclair's modified version while he has it in testing. It's all rather confusing because it seems like he is continuing to sell his special formula. Also I hunted for the research and found a listing that should have been completed some time back, but no results were given.
I had good luck with Chinese herbs and Accupuncture.
@@margaretsmith9637 oh really? Can you recommend any herbs? I was thinking of trying don quai. I can't afford acupuncture atm due to the cost of my supplements stack, but it's on the list!
@@janineclemons746 the info is out there, it's just very dull trawling through it all. That's why I prefer videos listing their sources, much quicker. I'm in England so I use DoNotAge now so I just stock up and hope for the best.
@@ConnieWobbles Looking up Chinese fertility herb formula for women should give you more information. There is a 4 ingredient formula I liked with Dong Quai root, white peony root and I cannot remember the other two ingredients but it is a classic formula. I wish you good luck.
Hello, I take nmn, tmg, & trans resveratrol, I would like to add b1 & b12, do you think us safe
I really wish this channel would feature guests who don't have a commercial motive. I take NMN/NR, but I get my information from credentialed sources (reputable MDs and PhDs) who aren't selling the supplements. Same with cosmetic products and devices. It's just more credible to rely on evidence-based research and get information from people who aren't promoting their products.
So if you use otc brand which do you use?
What brand NMN do you use?
@@inthemystery8297 ProHealth Longevity. It's one of the few that have been tested to show that it actually contains the amount of NMN claimed on the label. If you can, get on their mailing list to get discounts. I usually by mine in bulk when they have their big annual sale. I've also taken NR from Renue by Science.
@@PolishPocahontass ProHealth Longevity. It's one of the few that have been tested to show that it actually contains the amount of NMN claimed on the label. If you can, get on their mailing list to get discounts. I usually by mine in bulk when they have their big annual sale. I've also taken NR from Renue by Science.
@@C2C. proHealth Longevity NMN is made in china 😕 but thank you for the reply! 🤗
Thank you Clare for your investigative interviews.
My understanding is to take resveratrol with NMN, this is the advice I have heard from scientists studying the area of epigenetics without direct monetary gain from marketing their own supplements.
Do you have any info or thoughts on this?
I see quite a few scientists recommending resveratrol, and my husband takes it along with NR. I eat a lot of plant foods rich in polyphenols so haven't prioritized resveratrol - but it's on my radar and I promise to take a closer look at it on the channel.
@@thehonestchannel There is a medical doctor from New Zealand (his name escapes me at the moment, Stanfield perhaps?) who studies supplements that purportedly promote anti-aging. After reviewing multiple scientiific studies on resveratrol, he has concluded that most of what we are reading and hearing is just hype, unsubstantiated promo, if you will, and more scientific research is needed to confirm or dismiss it as an effective contributor to our anti-aging protocols. He is here on You Tube. Also, David Sinclair refuses to engage in a discussion with him regarding his findings. I take resveratrol daily by the way. I would really like to know if I am wasting my money on a largely ineffective supplement?! It is fairly expensive.
@@jjtopp99 Dr Brad Stanfield? I've watched a few of his videos. Unfortunately with conflicting studies it's hard to give people definitives around supplements.
I also think it depends on your lifestyle and what you eat too. If you already eat a lot of polyphenol-rich foods then you may not need to supplement. Or you could hedge your bets and cycle supplements so you're not taking them all the time but for periods of time.
@@thehonestchannel what is NR?
NR is similar to NMN , Nicotinamide ribosode, I think.
I agree on the dreams!!
Super Oxido of Dismutase tablets
Is true works like anti-aging?
It is an anti ager but not to the strength of NMN.
Is it recommended to start taking mnm in your early 40ths? And how much is it recommended to take per day?
what does Berberine do for A1c if one already taking metformin?
I already started taking all NMN , TMG, CaAKG, RN I stopped for a while Berberine. Quercetin and Fisetin as well.
RN is what???
NR I meant, sorry
Alas, I am 7 months late 4 this giveaway.
Thanks 4 introducing the item anyways.
If you had breast cancer is it NOT recommended to take NMN . Thank you
Doesn’t berberrine inhibit lean mass muscle development
No B12 or B6 for cancer patients?
Berberine, Niacinamide, TMG, Psyllium Husk, Cider Vinegar.
OK where to start,,having been seriously ill for nearly 6 years I had nothing better to do than go down the rabbit hole that is anti-ageing and all that is connected with the subject,,I decided to give nmn a try it was not apparent over night that there was any improvement in any aspect of my illness but within 8 weeks my family and friends noted that I was more active and happy to interact with others around me I did myself note that there was an definet improvement overall but put it out of my head with the thoughts that it might not last or it was somehow a placebo,,,roll on to present I am able to complete a hole day at work and go to my bed later rather than come in go to bed routine that had become the normal,,,hopefully I can continue to improve so I can get my life back on track
I'm so glad to hear you're feeling well again!
What do you think about glutathione? Glutathione is supposed to have anti-aging effects and it is composed of three amino acids: 1) NAC (n-acetyl cysteine) which is also supposed to be anti-aging, likely because it is a precursor to glutathione 2) glycine which is also anti-aging for the same reason as NAC and 3) glutamine which is good for gut health.
I just started watching. I have taken all 3 of these supplements for 6 months and to be ownest with you i noticed no difference. That's why i stopped. Have a great evening!!
That's interesting to hear your experience. It's funny how these things affect people so differently.
@@thehonestchannel i have to add that i follow a ketogenic diet and i'm 42. Thank you for these very interesting interviews!!!
@@user-xm8ye5ti5f You're already turbo-charged then 😄
I have taken nmn supplements , TMG and berbrine ( which is also found in cinnamon if you drink cinnamon with hot water ) for a year . I noticed not much of a difference . HOWEVER when I took NAD plus via IV drip , that had a turbo affect on me , killed my sugar cravings , I have a sharper focus , better quality of sleep and decreased my anxiety substantially. And also I recover so fast from my work outs . I highly recommend taking the drips , they have a higher dose and goes through ur blood stream . Having said that I still take the supplements and I also take multi vitamins and probiotics developed by a neuroscientist . I also have a Celluma infra red panel that I am addicted too . 😅😊😊😂😂😂
Why not just take NAD supplements?
What about N-acetylcisteine?
What do with do with vitamins we take for other reasons. Like D3, K2/m7, magnesium, zinc, Q10,fish oil, B vitamin etc. B1 also.
I take several of those vitamins myself. I'm not aware of any issues taking them alongside NMN but you may want to talk to your physician about it.
Please clarify, the Doctor stated the study about NMN and cancer patients, and she said the study was actually using NR - she repeated that cancer patients should not take vitamin B, so is she saying it's safe to take NMN or not? ❤ I am a cancer survivor undergoing testing for a possible recurrence, and I've been taking NMN for almost 5 months ... Thank you!!
I'm following Dr. David Sinclair. He has years of experience in research. Interesting regarding Resveratrol, low dose to lengthen life. If you're older, perhaps the shadow of tumors in the background, high dose of Resveratrol ....seeks out and destroys possible tumours situation. So one product 2 different purposes. Check out the man. Damning thing..NMN banned in EU from this year. Why? Perhaps Big Pharma feels threatened?
Hi what about sirt 6, reservatol and spermidine
then before taking NMN I have to check myself for cancer???
Yes.
I tried this for a few years, different doses, premium quality products. No results whatsoever. It was worth a try, but a hit to my bank account.
Thanks for sharing your experience
I'm curious about your age. From what I've seen, the younger you are, the less of a difference. Another viewer mentioned Brad Stanfield, who is in his 30s, and some of his choices for his own supplements are based on his age. He has said he will do things differently after 40, 50, and more.
@@kmjdebay I was in my early 40s when I took NMN, mid 40s now. I follow Dr. Stanfield as well and he's actually stopped taking NMN and plans to start taking NR once he reaches his mid 40s. He's just not convinced about the research so far. It's hard navigating all these supplements as you always seem to have to take all kinds of different ones together . Once you start taking one, you need to take two other ones to counteract some effects of the first one. Then after you've done that for a while one of the people you follow in the field will come out with a video on why they stopped taking it. At least if it did something for me it would be worth the time, effort and money. Same with all the beauty products and devices. You start out very committed, but it just becomes too frustrating at some point. I'm on a cavewoman break for the time being, watching it all unfold from the sidelines.
I Heard that It’s Best to Take Berberine with Milk Thistle..
Is this available in Canada?
Renu by science in Florida has a much better postage rate than DoNotAge. These are the top two suppliers per their third-party testing. Victoria, BC.
If your taking Betaine and getting Gycine, shouldn't you take NAC as well.
What is the suggested dose of Berberine per day?
NMN Bio recommended we take 2 Berberine capsules a day but I am just taking 1 400mg capsule a day now.
Soooo Will the Cancer Grow FASTER if you Take NMN??? And Would it Be BETTER if the Cancer Subject take FISETIN Instead?
One very strange thing re NMN is eyesight.... February cataracts, July cararacts both eye, looking through fog. Mid August up to mid October taking NMN. Vague idea that i could see things, less fog ++. Ran out of MNM . Went to hospital specialist. Eyes are good! Now 6 days without MNM can't read small print, fog descends. There is no other explanation that i can imagine. Why aren't i taking MNM? Can't get hold of it. I have a supply in the EU customs and they aren't releasing it. Banned substance in EU. The long reach of big Phama.
That's so frustrating for you Ann. Thanks for sharing this and I hope customs release your order soon!
You should take trans-Resveratrol with the nmn.
There is no evidence to support this.
What about the decision to take NMN off the market?
Hi. We covered the FDA decision in our first discussion. I’ll include a link in the video description
Please run an nad test as soon as possible. Ideally you would run the test before the supplements, but you should do it soon to keep track of the progress. At your age your nad level should be at half of a teenager, so if you take the test now you can compare against that. I would be very interested i hearing your results. Also, you want to consider taking a biological age test, your biological age should decrease as you take NMN and TMG. If you take that test also please share your results.
@-TheHonestChannel ok thanks, acknowledged?
@@juliusctw where can you get those tests? What are they called?
I just got my tested and it was very low, he appears. That NAD boosters I was taking were not effective.
How do you test NAD? Where did you get tested?
Where does TMG naturally come from inside the body? Is it a hormone produced by the pancreas?
What is she talking about when she says NR ??? Might help to explain what it stands for
This is a follow-up to my first interview with her the previous week when we talked through that in detail. NR is nicotinamide riboside - another form of vit B3 and thought to boost NAD.
Interesting that no mention is made of Professor David Sinclair who pioneered all this research
She talked about him in our first interview - this was a follow-up
How can I get in Nepal nmn subliment
I do respect very much this expert's opinion. However, on anti aging diet, I would check Dr. Valter Longo and David Sinclair (both PhD too) which are the most importante experts in life style for anti aging purposes and their work is mainly scientific.
Would u show the original country of the NMN production?
Hi. You can send questions to support@nmnbio.co.uk
I hope NMN bio is not from the background of DoNotAge.
Berberine does reduce blood sugar, so if yours isn't going very high due to diet restrictions or diabetes medications, then your blood sugar may dip too low causing tiredness as well
Interesting theory!
What happens to the body when we take NMN for a month or two and then stop taking it? Would we feel the absence of the supplement?
That’s my question too. What happens if you stop.
It should be taken at least 6 months to restore the broken DNA. It will gradually raise NAD+ levels in our body only after a few weeks, but ideally, to see results on a cellular level, it should be taken for at least 6 months.
i wonder if there is also an element of a placebo effect on yourself and your parents. drug studies often report something like 30% improvement of symptoms in placebo groups (versus maybe like 70-80% improvement of whatever the actual drug is)
Yes, true, although my mum has seen no improvement so far.
That would be a cheap solution
How much Berberine to take?
What time should you take Berberine?
Does tmg increase low /bad cholesterol!
Are there any vitamins or supplements that cannot be combined with NMN, TMG and berberine? Would you know?
No, and that is a bit of an issue with vitamins and supplements, as recently flagged by Dr Brad Stanfield, on this channel. We don't know a huge amount about what happens when we combine multiple supplements.
Most of the advice said you should take Berberine 30 min before a meal. Is there any difference if you take 2 tablet (2 x 500mg) after dinner as you mention in the video?
I only take berberine if my meal contains more than 10 grams of net carbs. Working well so far.
I’ve tried berberine and it made me horribly nauseous. After stopping it I developed the most ravenous Hunger like ghrelin went into overdrive. Really threw my usual intermittent fasting regime right off. I’m reluctant to try again
Yes, I can imagine. Sounds like it's not the right supplement for you.
If you’re fasting you probably don’t need the insulin benefits of berberine
Honest: I will take your vitamins so I can have a pretty lady like you!
Since I started taking NMN I do seem to get up more frequently during the night (67 years old). It could be my imagination.
Take your NMN in the morning not in the evening or late afternoon as it can act as a mild stimulant. Also don’t drink much water (wine, beer, tea or coffee) in the evenings, I have a 1/3 glass of lite milk after dinner instead of tea or coffee and ever since I’ve never had to wake up to pee in the wee hours. The calcium in the milk also helps modulate the acid in my stomach so haven’t had any heart burn in bed either.
Take your NMN in the morning not in the evening or late afternoon as it can act as a mild stimulant. Also don’t drink much water (wine, beer, tea or coffee) in the evenings, I have a 1/3 glass of lite milk after dinner instead of tea or coffee and ever since I’ve never had to wake up to pee in the wee hours. The calcium in the milk also helps modulate the acid in my stomach so haven’t had any heart burn in bed either.
Take your NMN in the morning not in the evening or late afternoon as it can act as a mild stimulant. Also don’t drink much water (wine, beer, tea or coffee) in the evenings, I have a 1/3 glass of lite milk after dinner instead of tea or coffee and ever since I’ve never had to wake up to pee in the wee hours. The calcium in the milk also helps modulate the acid in my stomach so haven’t had any heart burn in bed either.
@@deanervik thank u
Nmn 1g for 3 months with no increase in energy. Everyone is different is just not for me. When I’m done with this 6 months I’m done with it. You guess what lol try again when I’m older. I use TMG in conjunction with it as well.
I take 500mg of NMN (based on human trials results) on Wednesday and Saturday mornings hours before eating my first meal at noon. Also I take resveratrol after dinner on Wednesday and Sundays, especially if there’s oils or fats in the meal. I was 56 when I started 4 years ago, feeling great so far, hair seems to have stopped greying 🤞 (To be precise I take 250mg in the morning on an empty stomach then the other 250mg in the afternoon between or before a meal)
Thanks for sharing this. It’s a really interesting approach and one I’ll speak to my mum and dad about. I’d rather not take NMN every day without breaks.
Have you reduced poor stress from your life?
Hi ! Is there a reason for you to cycle NMN only on Wednesday and Saturday mornings ?
@@thehonestchannel you could take the weekends off if concerned about long term use with no breaks.
Resveratrol isn't all that. A lot of the studies have been debunked
This is all based on anti-aging pioneer, Harvard's David Sinclair's protocol, which has proven results. I advise going easy on the berberine if you have stomach and digestion issues, as it caused terrible cramping in my intestines. I recommend Metformin (off-label) for blood sugar control for those that have similar issues.
What about the more absorbable form of berberine called dihydroberberine? Supposedly one can take a lower dose with less concern about side effects.
Berberine can also cause constipation.
I've long taken a whack of supplements - including berberine et al - but it would be rather more convincing here if the guest speaker wasn't peddling these supplements. Moreover, no mention is made of the simplest, cheapest and likely most effective way to reduce / eliminate insulin resistance, i.e., by intermittent fasting and time-restricted feeding (I eat mostly only within a 6 hr. window; so 18 hours fasting per day). These regimens also reduce carbs and result in caloric restriction (since you are simply eating only one to two meals a day). There is also the question of the bioavailability of NMN...and, naturally, the expense.