New Trends in Therapy for Androgenic Alopecia Part 1
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- เผยแพร่เมื่อ 17 ต.ค. 2024
- In today's video, we are going to talk about New Trends in Therapy for androgenic alopecia. We will also discuss the myths surrounding finasteride's side effects, and more..
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Dr. Vikram Jayaprakash
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Malvern, Vic 3144, Australia
0395761465 atlantismedica...
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Dr. Russell Knudsen
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#hairlossproblems #hairloss #hairlosstreatments
Such an underratted channel! Thank u both for simple honest answers.
Thank you!
Keep it up docs we need alot more of this.
Lol your avatar is right at home in this corner of YT 😂
"New" trends in the treatment of male pattern baldness is a contradiction in terms! After minoxidil, finasteride and dutasteride, there has been no substantial medical progress in 25 years.
N covid vaccine came in 1 year
Happy to see both of your together again!!!
Started taking Dute with absolutely no side-effects, Again Thanks to both of you, for clearing the myths about the drug and spreading useful knowledge.
Cheers!!
Dute?
@@Nobody-hj6hh it's Dutasteride
@@Nobody-hj6hh Dutesteride
Dutasteride
You're going to be impotent very soon
I topically applied minoxidil on my scalp for three years, though now take the oral form and it seems to work just as well.
Your channel is sooo helpful. I started my therapy 3 years ago just by following your advice to the T and I certainly see results. And no side effects. Thanks
@@Outoffstreet+1
Thank you from the bottom of my heart for such a good, evidence-based, thorough content.
Can you explain to me why do i have this Bitter taste in my mouth i applied 2ml twice a day?
Anyone else experienced this?
amazin information! I didnt get the lastpart though:
Combining microneedling and Dutesteride and/or finesteride and/or minoxidil. Can u use everything / Should you use everything together?
Hi,
1. With regards to mesotherapy apart from the active ingredient dutasteride/ finasteride what should the inactive ingredients of the solution be?
2. Is there a risk of scaring? Apparently too much solution volume and incorrect inactive vehicle can cause scaring?
3. With regards to regular topical application of dutasteride/ finasteride what is the best vehicle? I have heard that it needs to be lipophilic to be properly absorbed eg liposomal or trichosol whilst alcohol penetration is very poor. Also some companies add growth factors like trichoxidil so thoughts on this would be good. Many thanks
What are your thoughts on the current trend in Spain by Dr. Vaño of starting people off Dutasteride 5x Week + Dutas Mesotherapy? He's named one of the top doctors in Spain.
Been watching your show for months & I've noticed you're on the other side of the spectrum, taking way less dosage & more infrequently.
When you use topical finasteride, even if you would use it on a balding area wouldn’t it penetrate the skin and ultimately reduce the DHT levels and thus work on thinning areas also? In other words, it’s simply a different delivery system to drop DHT levels? Therefore, why does it matter where it is applied on the head?
The idea of topical finasteride is that it works directly on the 5AR (enzymes that block DHT formation) found on the scalp. Ideally, you wouldn't want to affect your systemic 5AR (in the blood, in other organs as well), because that is where you could potentially get side effects from. But concentration matters for topical finasteride. If you use a concentrated one, it would significantly affect both of the 5AR on the scalp AND other parts of the body, which is the same as taking oral finasteride.
Can you talk about the new Derma stamps (vs the typical derma roller and dermra pen -- like Dr. Pen)?
Started topical minoxidil plus finasteride combination on July 18 2023… eagerly waiting for results…will update after 5months
If oral min doesn’t work you could try topical Stemoxydine
@Joekbk update?
Update? Good or bad?
Please, please, please, talk more about mesotherapy. I think my doctor here in South America has never done a treatment based only in the use of mesotherapy, without any oral alpha reductase blocker. She said I will be doing mesotherapy each six months, but you guys said 2 months and maybe it is because two months is the ideal frame when mesotherapy is the only technique being used as a treatment. Please, talk about this. I may suggest my doctor that I will be doing it each two months. She will agree.
Great episode!
Here in the UK I was introduced to GFC (Growth Factor Concentrate). It seems like it's a variation of PRP but some sort of growth factor activating proteins are added to the solution before injection. I was curious as to what this really is. Is it something that you doctors are familiar with but under a different name or something else. Naturally, I was curious about the effectiveness of it as well.
I've heard it had better performance than regular PRP, but it might be a bit self-induced thinking. I would love to hear your thoughts on this. Thanks
Same here in Australia and the price is more expensive than the PRP treatment
You existing hair will become really thicker but do not expect any hair growth on bold area….
@@gumnaamhubhai4063 well, you can say that about any non-surgical hair treatment. I want to know exactly how different it is to PRP
I understand from friends losing their hair that finasteride will make your phallum bway bway fall off
As a woman , with hair loss I don’t give a flying hoot if my body is covered in hair , if it grows hair on my head I’m taking it
Started using Finasteride July 28th 2023.
Exactly the same date as me, snap! Good luck with it.
@@schumanhuman hey bud keep me updated. I want to start them but am kinda overweight now (BMI is 27) and afraid of gynecomastia. What is your take ; am I over reacting ?
@@SHAMSHERA- I'm not medically qualified to advise but from what I read It appears to be generally low risk (
@@SHAMSHERA- Hey. I've been on the medication for the past 9 years. One thing I've learned is that, nearly all of the side effects are reversible. So, if you (God forbid) had an unwanted side effect. You can either reduce the dosage, or reduce the frequency, or stop the medication. Everything will then go back to normal. Its a win win situation. Answering your question. Yes, you are over-reacting bud. but it's normal. Good luck!
@@KhalidFikree My side effects went away after 1 year on finasteride. Now i'm fighting against oral minoxidil sides
Guys. There are now 3 “Minoxidil Boosters” on the market that supposedly up-regulate SULT1A1 in the ORS to improve performance for those that don’t respond. Only one of these has good science IMHO and this is now on sale in Asia (not the USA where it was developed). Also in Brazil you can buy Minoxidil Sulphate topicals directly. Btw. It’s the same enzyme in the liver, just a lot more of it. Lastly, Minox directly impacts the Androgen Receptors and effectively blockades the DHT.
Question: are there any supplements, like silica or biotin, that are actually worth taking alongside Finasteride?
Vitamin D with K-complex, collagen peptides, creatine, fish oil, TMG, hyaluronic acid, niacin, zinc, magnesium, glycine, NAC, citrulline
Not really, Biotin wont do anything unless you have a deficiency
@@wx2999creatine cause hairloss
Eat well. You will get the vitamins and minerals you need.
@@daveduffy2823 that’s not true. And vague, anyway.
Hi there, love your videos! Would it be possible to get a video discussing insomnia as a side effect of Finasteride?
Liked the bit about Loniten & liver
Hi to both doctors- I’m really keen to get your take and opinions and the recent trials using verteporfin to help with almost eliminating scarring and possible hair regeneration providing a possibility of infinite donor area.
Hello Doctors. Can you address the theme of an eventual relation between epilepsy treatments such as oxcarbazepine or levetiracetam and hair loss? Is there any known relation or study on this subject? Is there a need for regular blood analysis for a person who takes these drugs to make sure that they don't worsen hair loss? Thanks, and keep up the good work you're doing.
Topical finasteride solutions should be very cheap however there are few options available on the market and they are all quite expensive.
Where's the best place to get topical finasteride at a reasonable price?
Do I have to wash my hair with sulfate shampoo anti hair loss forced?
can dutasteride make hairloss worse?
i was on finasteride for 4 years with good maintenance but wanted more growth. i started dut 8 months ago and have lost a lot of density at the temples and my scalp is hurting. what should i do?
Since dutasteride raises testosterone, maybe that’s what’s making you lose hair. But it could be maybe a really long bad shed. I had that with fin where I shedded 100-200 hairs shampooing for like 4 months and I remember wanting to quit so baldly. Now I lose around 5 hairs. So maybe wait it out.
sounds like you're going through a shed. The hair will grow back, just stick with 0.5 dutasteride. at 0.5 dht levels will be reduced near 98%, no need to go up to 2.5.
@beace4436 Stay on dut for a year. If at that point you’ve only noticed loss of density and AGA progression, go back to Finasteride. You might have the rarer gene that alters genetic response to dutasteride and where you will respond better on fin
You talk about missing hair stem cells in the bald area. I thought stem cells never disappear but can be disabled.
How deep length should the derma roller be? What do you know about absorption into scalp for topical dutasteride? Would it be worth getting a longer dermaroller. Currently have 0.5 depth
1mg per day finasteride 5mg oral minoxidil great combo!!
But What about dck discfuntion?
@@facundomillan2703 I haven’t experienced that
Btw doctor whats your thoughts on people consuming drops of minoxidil liquid. Not asking for recommendation cause its clearly wrong but just your thoughts on it.
In part 2 please cover pyrilutamide and saw palmetto.
What are these??
@@sanket1769pyrolutamide is a very promising upcoming drug which is act like a topical anti androgen
While saw palmetto us so called natural finasteride alternative which practically don't do jackshit
@@sanket1769saw palmetto is a plant & taken as a supplement. People take it for skin, hair, and prostate issues. However, I have read it should be avoided if taking Finasteride unless okayed by Dr....Like all unregulated supplements, we don't really have great science on it IMO.
Pretty sure they have a video on Pyrilutamide posted on March 3, 2023.
@@voice_of_a_little_lady what's that??
Can you talk more about a person’s predisposition or risk of prostate cancer with the use of drugs like finesteride/dutasteride? I don’t feel that this topic has even been touched on.
Doc, we need your opinion on emerging treatments like SCUBE3, GT20029 and Pyrilutamide
There’s one thing I’m unclear on regarding topical 5a-R blockers. Can they work in a localized fashion, or is it required for them to be systematically absorbed to work?
Topical won't work
@@Nobody-hj6hh blanket statement, patently incorrect too
Is it called miso therapy?
And is it available in aus?
I think that changing the diet is a major factor in the use of minoxidil in as efficacy many people eat a western diet which is full of chemicals and manipulations that are initially just bad for the human body and health so may be changing the diet to a more clean and natural source for nutrition could be key in the utilization of things like minoxidil. Frankly I do notSuffer boulders but I have many friends with you and I noticed that they eat a very impure and putrid diet and they use things like minoxidil with minimal results, anyway it’s just a thought on my part I think proper nutrition things like fasting which also encourages the body to regenerates cells and mitochondria is another way to go
Topical Pyrilutamide with oral fin and oral min is working well for me
Where u get pyrilutamide?
Doctor what is your opinion on bicalutamide for hair loss in women. I was on finasteride 5 mg since 5 years but my Dermat just switched me to bicalutamide. Do u think it works well in women?
Did your Dr say why they have switched you? Were you having side effects on fin? Hope you’re doing well 😊
Finasteride was working very well.. however last year I noticed that my scalp was showing a little again.. so he said that probably finasteride had done whatever it could for me and switched me to bicalutamide.. I have no clue whether it is the right thing to do..
@@ridhimaagarwal6142Hi and thanks so much for responding. Really appreciate it! Have you seen any changes with the Bica. as of yet ? Wishing you good luck and happy hair 🙏😊
@@PandaA-cv3mm no changes for hair yet.. but my skin has become drier and headaches have increased.. I still won’t to give bica some more time to see how it works
I had a hair transplant one year ago. I never had shock loss or not that much of it. So lately I have been seeing loss of hair with a small ball connected. what's going on?
Shave your head. Current technology isn’t there yet to achieve meaningful hair gain…you’re going to be disappointed and have spent a lot of money with scars and a hairline you’re embarrassed of.
The only people I trust. 👏👏👏
Oh dear. Big mistake.
Do you know/think there will be any research into the gene that causes DHT sensitivity?
Nope. Big pharma wants you to keep buying their pills
🎉🎉🎉🎉🎉 Russel is back
Hey doc, would you recommend a Dr. CYJ hair filler for young male hair thinning in the scalp?
Good day dr. Will finasteride affect athletes performance? I see many high level athletes such as rafael nadal, wayne rooney, lebron got multiple hair transplants but continued to thin presumably of not taking finasteride. I play tennis and soccer at an amateur level and don't want finasteride to affect my performance. ( I am 21 years old with diffuse thinning on my crown and mid scalp)
It won’t affect strength/muscle size per say but can decrease your aggression to or “drive” which,particularly for a very physical contact sport I can see it affecting it. Now weather it does that to you and if so how much is dependent on the individual.
What about KX-826 and Breezula and their future potential?
If we block 5 alfa reductase which lower dht and increases tes. ,,,will that high tes. be converted to estrogen by aromatase inhibitors
Interesting as always! Are you on medical treatment for hair loss yourself?
Does derma rolling create any damage on existing good hair? If no then why?
YES. STAY AWAY FROM DERMA ROLLING
Please make a video about stem cell therapy for hair growth. Does it work? I have androgenic alopecia and been doing cortisol steroids and mesotherapy treatments but there’s very little to no progress.
Hhhhhhhzph 🚧🚢
Doctors great video . GFC injection is popular. But what about injecting stem cells derived from Adipose Fat cells from.abdomen area of same person. Can this give better results than Growth factor concentrate( GFC)? Please reply doctors
Thank you Dr Russel and Dr Vikram
in another episode you mentioned that a topical formulation still needs to go systemic in order to have effect.
As i understand now, it is can be localised.
So oral solution has no greater value?
What should you do if minoxidil doesn’t work on you? Can you get that sulfate thing elsewhere, or should you forget about minoxidil?
Add tretinoin to your scalp
@@Chonny_Boy should you do that before minoxidil?
@@alexkreyn315 You can do it anytime really. If you don’t have sensitive skin then you can put tretinoin on before bed, wait 15 minutes, and then apply the minoxidil. Both of these can irritate your skin so if you have sensitivity then you may want to put on tretinoin at night (as it is photosensitive) and then minoxidil in the morning.
Does finestride grow body hair also?
Anything on pep factor for hairloss? Are there any comparative studies to PRP?
I have no interest in localized topical solutions. Anything that soaks my head/hair for 2 hours twice a day, prevents me from sweating for 8 hours a day, and makes my hair look nasty unless washed, is terrible. I was so excited to be put on oral, I couldn't care less if I grow back hair.
i lost mine out of shock can i be helped
Any benefit to taking both topical and oral minoxidil?
A heart attack
Hi, can Bupropion leads to hear loss?
Doc, is it true that minoxidil causes cardiovascular issues and even ED?
great vid, interested to see what you guys will be talking about in part 2
Coming soon!
Hello ! The first time I used Minoxidil my hair grew and my scalp was not dry. I took a break and returned to Minoxidil 2% for the second time. Please advise me, I have been using Minoxidil 2% for about 10 months, at first the hair loss decreased, scalp became dry, short hair falls out. Now the hair loss has increased. Is there any sense to change to Minoxidil foam 2% or not? Maybe 2 % does not work anymore, that's why hair is falling out and we should switch to 5 % and how to get rid of dry scalp? Thanks !
What about SAW PALMETTO???
Garbage
What are your thoughts on microchanneling with ProCell for androgenic alopecia?
USELESS
Great video! Thank you! :)
Glad you liked it!
Please,
How about Trioxidil?
10:15 People with mega-responsiveness to treatment (reddit/tressless) for a long time completely bald zone is this a fake?
reddit does have lots of fakes trying to advertise. posting before and afters that should be impossible without a hair transplant, probably promoting hims/keeps/happy head etc.
@@WALTAH2000 yes, but there are unique examples like Apti Eziev, where the result even if minoxidil and finasteride and 2 transplants the result is implausible
@@WALTAH2000 yes, but there are unique examples like Apti Eziev, where the result even if minoxidil and finasteride and 2 transplants the result is implausible
thanks for info doc👍
Always welcome
How does oxygen affect the hair
Hii sir i'm 21 years old suffering from AGA and on finastride 0.5mg daily at night from last 2 months but I'm having erectile dysfunction in night but it's normal in day time can you please help me sir
Try topical finasteride
Great video! What about Latanoprost and Procapil?
Tried myself topical latanoprost, very expensive and almost no visible effect after 4 months, I switched to topical minoxi + dutasteride and had way better results at a fifth of the latanoprost price.
Thanks for sharing Rick!@@rick23ro
Procapil is horrible. Redensyl is better
Can't you just solve this mystery.. it's overwhelming
Nice info docs ❤️
Thank you 🙌
Thanks 🙏 Good information.
Glad it was helpful!
Docs. Thanks for videos...i am 67...take daily tadalifil and 2.5 mg oral mioxidil a day ...your opinion...how should i take them...please ..thanks again
P.s. tadalifil is 5 mg..
@@jimijames6369isn't tadalifil the same as viagra?
I would use tadala morning...and oral minox at night.
But I'm quite sure If you take both in the morning wont be a problem. 2.5 of minox is a small dose. For blood pressure the usual dosage (minimum) is 20mg. Make a test.
Could you please talk about DUPA, retrograde alopecia, and alopecia areata incognito? I'm currently thinning on the sides and on the back and I wonder if you could offer any advice on rarer forms of alopecia? Also, you kind of alluded to this in your video, but could you discuss more about why some medications have no response on the user. Like when you were discussing that minoxidil can only work on certain types of people who have a corresponding enzyme that allows the medication to produce results.
I‘m also suffering from something like DUPA or retrogade alopecia as i‘m thinning agressively on the whole head (also sides) despite being on dutasteride the most POTENT medication. I started with Dut 9 years ago but yeah.. norwood reaper still destroying my hair. About to give up.
@@simonecusumano3170 Yeah. I'm thinking it might not even be related to DHT. It might just be inflammation of the scalp triggered by an autoimmune disease or something. It's great for other people out there who have min/fin/dutasteride to fall back on but for these other types of alopecia, there needs to be more research on how these problems are triggered in the first place. It's really frustrating when you don't even know the reason why your hair is falling out and no one can really tell you. I'm not even sure if a scalp biopsy would help in these circumstances. I've looked into other stuff like RU58841 and jak inhibitors, but really not sure if I want to go that far with treatment personally.
Hey so I have dupa as well. Maybe not dupa but like a scarring type of hairloss in the lower back. What helped me was the following 1) minoxidil sublingual 1mg a day. 2) minoxidil foam. 3) topical finasteride + 0.003% lantanaprost + some steroid from happy head. That literally eliminated any itchiness I was having in my head. 4) 0.1% topical lantanaprost from strut 5) topical dutasteride 0.025% mixed with steroid and 7% minoxidil. Good luck
I have been taking topical minoxidil daily for around 7 to 8 years but now the greasiness of scalp and on some hair coupled with a few pimples/spots sometimes on scalp is enough. So want to switch to oral minoxidil. I have never suffered any sides on minoxidil regarding fatigue, cardiac or breathing problems. Ive had numerous fbc blood tests over the years always come back in the good to normal ranges as told to me by my gp but my gp refuses to prescribe me oral minoxidil and advises me to keep applying topical minoxidil but the greasiness and a few pimples are irritatting now so I would like to know what amount should i start oral minoxidil on? 1.25mg, 2.5mg or just like the topical minoxidil of 5% once daily? Fearing that if I start too low on 1.25mg I might start losing hairs instead so would it be wiser to start on 2.5mg for say 2 weeks and see if I get any sides and if not then jump onto the same 5mg x once daily tablet? Pls reply and your advice, experience and opinions are most welcome. TIA
Oral monoxidile is too strong. I am taking 1.25mg and experiencing dizziness and a light head.
I'm 20 years old can i take finasteride??plz answer
Get a pill cutter, cut 1mg pills in half and take 2 or 3 days a week, check the side effects for a month. If non sides, up the dose. I experienced side effects so dropped it for now
Could you do a video on Alopecia Areata incognita?
can we get a TLDR?
Finasteride made me depressed and impotent for 9 months 😮 i know some people even get suicidal because of this😮😮
Have you recovered by 100%?
How long topical finasteride remains in sculp? How many times a week it should be applied??? HELP ❤😢
24hrs - take it 4x a week it’s what I’ve been doing for 6 months now
@@RiskyTingz08how did you get topical finasteride? And did you have any side effects?
mixed myself, side effects dissapear after 1 month @@mohammadismat5490
Good day dr.. I was using minoxidil topical application and finasteride 1 mg for past 2 yrs under the guidance of an dermatologist. Dr told to switch minoxidil topical to oral minoxidil as he didnt find good result. And the oral minoxidil was continued around a year.
For the past 4 months i stopped the oral minoxidil and was continuing with only finasteride as i felt palpitation whn i do works.
But now my hairs r shedding which worries me a lot. Can my hairs be back to normal since i m still using finasteride?
Had u gt any results with the oral minoxidil?
Tks a lot
2:11 I thought 👹🫣
No mention of Prp or lllt?
Both are scams
@@hasan6678 hey buddy, is this your opinion or medically proved? Thanks
@@raymondfitzgerald521I've been doing it since January, and I don't think it's that effective to be honest :( I will be on my 6th session in a few weeks
@@raymondfitzgerald521waste of money.
@@raymondfitzgerald521sacms
Minoxidil saw palmetto should be banned it’s such a pain in the rear to use and it’s expensive as hell and it’s all fake or damages ur testosterone
LONG-WINDED INTRO
Take 0.5 mg finasteride every 2 weeks and thats all you need. Everything else here is over complicated
I have androgenic alopecia all thanks to birth control :(
These are old treatments
5 more years… 😂
Another red skull? Curse yo guide you to a thresoure he cannot possess!!!
1st 🙂
Did they say anything?
The older gent has a good head of hair but I guess he can't do anything for the gray?
Uh what’s the new trend?
Their is nothing you can do about going bald