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advice, tips, and tricks: ● Consume whole, minimally processed foods: The presenter emphasizes the importance of eating whole, minimally processed foods rich in anthocyanins, rather than relying on supplements. ● Recommended daily intake of anthocyanins: While there is no established RDA for anthocyanins, consuming 100 grams (approximately 1 cup) of blueberries per day has been shown to produce significant physiological differences in reducing oxidative stress. ● Freeze-drying is a superior preservation method: Freeze-drying is a fairly effective preservation method when it comes to antioxidant value and anthocyanin content in berries. ● Be cautious of longer, slower drying methods: Longer, slower drying methods can result in some loss of anthocyanins due to exposure to oxygen. ● Cooking can be beneficial: Cooking can bring a vegetable or fruit to a place where it can be eaten more conveniently and safely, but be aware that excessive heat processing can lead to a loss of anthocyanins. ● Organic farming chemicals may not significantly affect anthocyanin levels: Organic farming chemicals approved by governing bodies are unlikely to affect anthocyanin levels significantly. ● Be skeptical of supplements: The presenter is skeptical of supplements that contain refined molecules, as there is not enough data to support their effectiveness in reducing disease risk. ● Eat a variety of anthocyanin-rich foods: Consuming a variety of anthocyanin-rich foods, such as blueberries, blackberries, cranberries, and raspberries, can provide significant health benefits. ● Consider the source of dried fruits: When buying dried fruits, consider the processing method used, as some methods may result in a loss of anthocyanins. ● Understand the importance of anthocyanins in human health: Anthocyanins have been shown to have a significant impact on human health, including reducing oxidative stress, inflammation, and the risk of chronic diseases. sources of anthocyanins, along with their ratings: ● Black currants - extremely high concentration, described as "incredibly dark almost black" (Rating: 9/10) ● Elderberries - very high concentration, described as "incredible medicinal properties" (Rating: 8.5/10) ● Blueberries - high concentration, described as "the fruit that had the highest anthocyanin content and was also widely available" (Rating: 8/10) ● Bilberries - high concentration, mentioned alongside blueberries and blackberries as top sources (Rating: 8/10) ● Blackberries - high concentration, mentioned alongside blueberries and bilberries as top sources (Rating: 8/10) ● Pomegranates - moderate to high concentration, mentioned as becoming more common (Rating: 7/10) ● Dark plums - moderate concentration, mentioned as having lower anthocyanin levels than the top sources (Rating: 6/10) ● Red cabbage - low to moderate concentration, described as "not nearly as concentrated as most berries" (Rating: 4/10) ● Radicchio - low to moderate concentration, mentioned as containing some anthocyanins (Rating: 4/10) ● Beets - low concentration, mentioned as getting most of their color from other phytonutrients (Rating: 3/10) ● Tomatoes - low concentration, mentioned as having much lower levels than berries (Rating: 2/10) ● Eggplant - low concentration, mentioned as having some anthocyanins in the skin (Rating: 2/10) ● Kale - negligible concentration, mentioned as not having significant levels of anthocyanins (Rating: 1/10) When it comes to choosing berries, it is recommended to favor organic berries over non-organic ones. Organic berries have higher levels of polyphenols and do not contain harmful agrochemicals. Freeze-drying is a superior method of preserving berries, as it helps retain their antioxidant and anthocyanin content. On the other hand, the speaker advises against relying on supplements that contain refined molecules, as there is not enough data to support their effectiveness in reducing disease risk. Instead, the speaker emphasizes the importance of consuming whole, minimally processed fruits and vegetables, and cooking them in a way that makes them safe and convenient to eat. Avoid or limit exposure to certain toxins, such as those found in blue-green algae, artificial sweeteners, and heavy metals, as they can have negative effects on mitochondrial health and overall well-being. Diseases: ● Alzheimer's disease: anthocyanins have the ability to arrest or ameliorate the formation of amyloid tangles and plaques, which are associated with Alzheimer's disease. ● Obesity: anthocyanins have been shown to have a unique ability to help prevent obesity. ● Type 2 diabetes: anthocyanins have been shown to have a unique ability to help prevent type 2 diabetes or insulin resistance. ● Parkinson's disease: exposure to blue-green algae contaminated foods and water is a huge cause of Parkinson's disease. ● ALS (Amyotrophic Lateral Sclerosis): exposure to blue-green algae contaminated foods and water is a huge cause of ALS. ● Cancer ● Ulcerative colitis: anthocyanins are anti-inflammatory and have been shown to be protective against ulcerative colitis. ● Crohn's disease: anthocyanins are anti-inflammatory and have been shown to be protective against Crohn's disease. ● Cardiovascular disease: anthocyanins have been shown to have a protective effect against cardiovascular disease. ● Mitochondrial myopathies: heavy metals, such as lead, can cause mitochondrial myopathies. ● Neurodegenerative diseases: excessive levels of oxidative stress can lead to neurodegenerative diseases. These diseases are mentioned as being potentially preventable or treatable through the consumption of anthocyanin-rich foods, such as blueberries. Cancer: Anthocyanins, particularly those found in blueberries, have been shown to have a unique ability to help prevent cancer by preventing the initiation stage, which is the mutagenic component. They also have the ability to help support tissue differentiation, preventing a tumor from forming even if the initiation phase has already occurred. Additionally, anthocyanins have anti-angiogenesis properties, which can help prevent the development of blood vessels into a tumor, thereby preventing the growth of cancer cells. There are research papers demonstrating the protective role of anthocyanins and blueberries in all three phases of cancer etiology.

dear Dr. Bagnulo. thank you so much for the clear presentation and explanation. interesting that you mentioned Prof. Dr. lustig as a fructose expert. he has gained much of his knowledge on fructose from Dr. Richard Johnson. in contrast to what you said, Dr. Lustig does make a distinction between sugar from a fruit like a pear and high fructose corn syrup. the former contains fiber which according to Dr. lustig blunts the effects of fructose on the mitochondria and overall metabolic health. I welcome your feedback. kind regards, miss Reimara

great info

❤

What’s your opinion on Paul Saladino eating so much fruit? I know he’s really active but he’s said that he had good results with a lot of high fructose fruit and juice

Main points of the webinar: ● The importance of maximizing or increasing the ratio of polyphenols to fructose in one's diet. ● Polyphenols have very high antioxidant value, help preserve overall cellular health, reduce inflammation, and foster a healthy microbiome. ● Fructose, on the other hand, is a sugar that human physiology has difficulty metabolizing, leading to negative health effects such as increased uric acid levels, inflammation, and fatty liver deposits. ● The need to limit fructose consumption, especially in pediatric populations, and provides clinical considerations for avoiding high-fructose foods and sweeteners. ● The benefits of polyphenols in reducing the risk of chronic diseases, such as neurological diseases and neurodegenerative diseases, and promoting healthy aging. ● The importance of choosing lower-fructose containing fruits, avoiding fruit juice and dried fruits, and being mindful of portion sizes to safely handle fructose metabolism. ● Polyphenols have high antioxidant value, which helps preserve cellular health by protecting the mitochondria, cell membrane, DNA, and organelles, have anti-inflammatory properties, specifically through COX-2 inhibition, which can help reduce inflammation. ● The liver plays a crucial role in metabolizing fructose, and high fructose intake can lead to liver burden and health issues. Sources of polyphenols ● Dark berries, such as: * Black raspberries * Blueberries * Black currants ● Spices, such as: * Turmeric * Ginger * Cloves ● Herbs, such as: * Oregano * Basil * Parsley * Rosemary * Sage * Thyme ● Dark green leafy vegetables, such as: * Kale (especially Lacinato kale) * Swiss chard * Spinach * Beet greens ● Extra virgin olive oil ● Flaxseed oil ● Tree nuts, such as: * Pecans * Chestnuts * Hazelnuts (also known as filberts) ● Legumes, such as: * Peanuts (although they are not technically a tree nut, but a legume) ● Other fruits and vegetables, such as: * Cranberries * Green tea ● Pasture-raised meats and dairy products, which can contain polyphenols due to the animals' diet of polyphenol-rich plants. Macronutrients Macronutrients are mentioned as the primary components of plants, which include protein, carbohydrates (made up of fiber, starch, and different types of sugar), and lipids. These primary metabolites are contrasted with secondary metabolites, which include phytonutrients such as polyphenols. The speaker notes that when looking at plants, people generally think about the macronutrients, but the secondary metabolites, including polyphenols, are also an important part of the plant's composition. Polyphenols ● Anthocyanins: These are a type of polyphenol that are found in dark blue, red, and purple fruits and plants. They are considered to be one of the most potent polyphenols when it comes to medicinal value and the ability to neutralize free radicals. ● Resveratrol: This polyphenol is mentioned as being found in peanuts, which are actually a legume, and in smaller amounts in some tree nuts such as chestnuts, pecans, and hazelnuts. ● EGCG (Epi-gallocatechin gallate): This polyphenol is mentioned as being found in high levels in matcha green tea. ● Curcumin is a polyphenol found in turmeric and has been shown to have anti-inflammatory properties, particularly in the context of neurogenic diseases and major depressive disorder. Curcumin has been found to suppress various inflammatory pathways, including cyclooxygenase, endothelial nitric oxide synthetase, and nuclear factor kappa beta, among others. However, it is noted that curcumin requires heat to increase its bioavailability, and consuming it with a lipid or oil can enhance its absorption. Additionally, Polyphenols are a broad class of phytonutrients that include flavonoids, tannins, and other types of phenolics. However, the specific polyphenols mentioned above are the only ones that are explicitly named in the documents. Anthocyanins Anthocyanins are a type of polyphenol that are found in dark blue, red, and purple fruits and plants. They are often involved in the plant's protection against ultraviolet light and are considered to be one of the most potent polyphenols when it comes to medicinal value and the ability to neutralize free radicals. Anthocyanins are typically at the top of the list when measuring the most potent polyphenols, as determined by an oxygen radical absorption capacity (ORAC) test. They are also responsible for giving plants a blue, purple, red, and sometimes even a very dark almost black pigment, as seen in the case of black currants. Advice, tips and tricks: ● Maximize or increase the ratio of polyphenols to fructose in one's diet. ● Prioritize vegetables over fruits, as vegetables are generally lower in fructose and higher in polyphenols. ● Choose whole, minimally processed, brightly colored fruits and vegetables to get the most polyphenols. ● Use extra virgin olive oil for most cooking, as it is a great source of polyphenols. ● Use flaxseed oil whenever possible, but keep it away from high heat and moderate heat applications. ● Emphasize organically grown sources, as they tend to have higher polyphenol content due to the plant's natural defense mechanisms. ● Avoid the use of sweeteners, and if necessary, use Stevia, which is a natural sweetener that doesn't contain fructose or free sugar. ● Choose lower fructose-containing fruits, such as those with less than 2 grams of fructose per cup. ● Avoid fruit juice and dried fruits altogether. ● Limit fructose intake to less than 10 grams per meal and less than 25 grams per day for most adults. ● Be aware of the signs of fructose intolerance, such as high triglycerides, and consider subsequent testing, including a uric acid test. ● Use the USDA database to find accurate information on the fructose content of various foods. ● Consider the polyphenol content of spices, herbs, and dark green leafy vegetables, which are rich in polyphenols. ● Incorporate the four major families that contribute the largest amounts of polyphenols into one's diet, including: * Spices (e.g., turmeric, ginger, cloves) * Dark berries (e.g., blueberries, blackberries, currants, cranberries) * Herbs (e.g., oregano, basil, parsley, rosemary, thyme, sage) * Dark green leafy vegetables (e.g., kale, spinach, beet greens) ● Reduce uric acid presence in the liver by facilitating its excretion and reducing fructose intake. These tips and tricks aim to help individuals optimize their polyphenol intake, reduce their fructose consumption, and promote overall health and well-being.

Tips, tricks, and advice ● Balance Omega-3 and Omega-6 fatty acids: Higher levels of Omega-3s and lower levels of Omega-6s can reduce inflammation. Aim for a 1:1 ratio, especially for individuals with chronic inflammatory conditions. ● Choose the right oils: Replace industrial seed oils with black seed oil, olive oil, or coconut oil for cooking, as they have a more favorable Omega-6 to Omega-3 ratio. ● Limit fructose intake: Focus on fruits with lower fructose content, such as berries and citrus fruits. Limit or avoid fruits with high fructose content, like bananas and mangoes. ● Increase vegetable fiber intake: Aim for at least 25 grams of vegetable fiber per day to promote a balanced microbiome and reduce the risk of dysbiosis. ● Avoid gluten and A1 casein: Gluten and A1 casein can cause inflammation and increase gut wall permeability. Consider eliminating or replacing them with alternative options. ● Use natural sweeteners judiciously: Limit the use of refined sweeteners, even natural ones like honey and maple syrup, as they can desensitize you to natural sweetness and have negative effects on the microbiome. ● Choose alternative sweeteners: Consider using Stevia, Xylitol, or raw unfiltered honey as alternatives to traditional sweeteners. ● Read labels carefully: Be aware of the ingredients in food products, especially those that may contain omega-6 dominant seed oils, sweeteners, or A1 casein. ● Focus on whole foods: Prioritize whole, unprocessed foods, including vegetables, fruits, and root vegetables, which are rich in nutrients and fiber. ● Maintain a balanced microbiome: A diverse and balanced microbiome is crucial for reducing inflammation. Focus on promoting beneficial bacteria through diet and lifestyle choices. Macronutrients: ● Carbohydrates: Specifically, the documents discuss the importance of choosing carbohydrates that are low in fructose and have a low carbohydrate density. Examples of carbohydrates mentioned include glucose, fructose, and fiber. ● Fats: The documents mention the importance of choosing healthy fats, such as olive oil, flax oil, and coconut oil, and avoiding omega-6 dominant seed oils like sunflower, safflower, soybean, and corn oils. ● Proteins: The documents mention the importance of avoiding certain proteins that can cause inflammation, such as gluten and A1 casein, which is found in many U.S. dairy products. They also mention the importance of choosing proteins that are low in inflammatory compounds, such as those found in pea protein. Choose macronutrients that are low in inflammatory compounds and high in nutrients in order to reduce inflammation and promote overall health. Fiber: Fiber is discussed in the context of its role in reducing inflammation and promoting a healthy microbiome. The speaker emphasizes the importance of consuming at least 25 grams of vegetable fiber per day to maintain a balanced microbiome and reduce the risk of dysbiosis. It is noted that not all types of fiber are created equal, and that vegetable fiber is the most beneficial in terms of providing protection against inflammation and promoting the growth of anti-inflammatory compounds such as n-butyrate. The speaker distinguishes between vegetable fiber and other types of fiber, such as fruit fiber and whole grain fiber, suggesting that these types of fiber do not offer the same level of protection against inflammation. The speaker also highlights the importance of fermentable vegetable fibers, which are found in vegetables and legumes, in providing risk reduction against specific diseases such as cancer and in producing an overall anti-inflammatory environment in the body. In contrast, it is noted that bran and highly refined fibers like inulin do not offer the same level of protection. Overall, the speaker emphasizes the importance of consuming a diet rich in vegetable fiber in order to promote a healthy microbiome and reduce the risk of inflammation and related diseases. Avoid ● Industrial seed oils, specifically: * Safflower oil * Sunflower oil * Soybean oil * Corn oil * Sesame seed oil * Peanut oil ● High-fructose foods and sweeteners, including: * Agave * Apple juice concentrate * Orange juice concentrate * High-fructose corn syrup ● Gluten, especially in cases of inflammatory-based conditions ● A1 casein, found in most U.S. dairy products, particularly those made from Holstein cow milk ● Processed foods with high levels of omega-6s and fructose ● Foods with high levels of added sugars, including: * Fruit juice concentrates * Sweetened products ● Foods with high levels of omega-6 dominant oils, especially if they are among the top ingredients. Apples and mangos are mentioned as fruits that have higher fructose contents. The speaker advises that these fruits should be consumed in moderation, suggesting that people should "save the higher fructose containing fruits such as mangos, apples, bananas" and not have multiple servings of them per day, as this could exceed the amount of fructose that would be tolerated by most individuals. Table sugar is mentioned as being composed of 50% glucose and 50% fructose. It is also noted that table sugar has a carbohydrate density greater than 100, which is not favorable for the microbiome. Additionally, the speaker mentions that table sugar contains a significant percentage of fructose, which is a concern due to its potential to drive inflammation and other negative health effects. The speaker advises using sweeteners, including table sugar, judiciously and saving them for special occasions or specific recipes, as they can desensitize people to the natural sweetness found in whole foods. Favor According to the webinar, there is no mention of what to favor. The webinar focuses on what to avoid in order to reduce inflammation, such as industrial seed oils, high-fructose foods and sweeteners, gluten, A1 casein, and processed foods with high levels of omega-6s and fructose. However, it does mention some exceptions and alternatives that can be used in moderation, such as: ● Olive oil, which is considered a neutral oil and can be used in abundance ● Flaxseed oil, which has a favorable ratio of omega-3s to omega-6s ● Coconut oil ● Walnut oil ● Black seed oil (recommended as a replacement for industrial seed oils) ● Avocado oil (mentioned briefly, but not discussed in detail) ● Stevia, which is a natural sweetener that can be used as a substitute for table sugar or maple syrup ● Xylitol, which is a sweetener made from North American hardwood trees and birch trees ● Raw, unfiltered honey, which has antioxidant value and can be used in moderation It's also mentioned that vegetable fiber, particularly from vegetables and legumes, is beneficial for reducing inflammation and promoting a healthy microbiome.

what contributes to mitochondrial biogenesis ? free radiacls. molecules with un paired electrons . dha is polyunssaturated but critical. things get put into simplistic baskets but often have conflicting roles

A lot of chlorpyrophos is used on sweet potato for nematodes

Tips, tricks, advice: ● Eat whole foods: Emphasize the importance of consuming whole foods, including whole vegetables, legumes, whole grains, and nuts, to support a healthy microbiome and reduce gut permeability. ● Include fermentable fiber: Highlight the benefits of fermentable fiber in reversing gut permeability and improving immune function. Examples of fermentable fiber-rich foods include whole vegetables, legumes, and berries. ● Avoid ultra-refined foods: Recommend avoiding ultra-refined foods with high carbohydrate densities, which can exacerbate gut permeability issues. ● Choose the right oils: Suggest using whole seeds and nuts instead of refined industrial seed oils, which can be detrimental to gut health. Olive oil, in particular, is recommended for its anti-inflammatory properties due to its polyphenol content. ● Be mindful of gliadin: Discuss the negative impact of gliadin on gut permeability, even in individuals without gluten intolerance. Gliadin can increase intestinal permeability, which can last from four to eight hours in non-celiac individuals and weeks in celiac patients. ● Consider stress management: Mention the role of stress in gut permeability issues and the importance of managing stress to maintain a healthy gut. ● Assess gut permeability: Provide guidance on assessing gut permeability, including looking for signs of multiple food allergies, using the Mannitol recovery test, and considering the patient's history. ● Use supplements wisely: Discuss the potential benefits of certain supplements, such as vitamin D, zinc, curcumin, and epigallocatechin complexes, in reducing gut wall permeability. However, emphasize the importance of using these supplements judiciously and under the guidance of a healthcare professional. ● Prioritize a diverse microbiome: Emphasize the importance of maintaining a diverse and balanced microbiome, which is critical for healthy lung function, immune function, and overall well-being. ● Seek professional guidance: Encourage individuals to consult with a healthcare professional to determine the best course of action for addressing gut permeability issues and developing a personalized plan for improving gut health. Fiber Fiber is considered an essential nutrient that plays a crucial role in maintaining a healthy microbiome. It is emphasized that fiber is not just important for regularity, but it also has a functional component that goes beyond that. The text highlights the importance of having an array of fiber, which historically has not been looked at as an essential nutrient. It is also mentioned that fiber is every bit as essential as protein, essential fatty acids, and the carbohydrate content of a diet. Fermentable fiber, resistant starch, and ligands, are found in whole vegetables, legumes, and berries. These types of fiber are important for supporting the growth of beneficial bacteria in the gut, such as bifidobacter and fecal bacter, which produce butyrate, a short-chain fatty acid that is essential for maintaining a healthy gut wall. Higher levels of dietary fiber are associated with a greater representation of microbial species that provide tighter intestinal walls and lower levels of intestinal permeability. It is also mentioned that fiber content is equally important as protein content in maintaining a healthy microbiome. Overall, the text emphasizes the importance of fiber in maintaining a healthy gut and microbiome, and highlights the need to include a variety of fiber-rich foods in one's diet. Protein Higher levels of dietary protein are associated with a greater representation of microbial species that provide tighter intestinal walls and lower levels of intestinal permeability. This is mentioned in the context of discussing the importance of fiber and protein in maintaining a healthy microbiome. It is stated that both protein and fiber are equally important in supporting the growth of beneficial bacteria in the gut, such as bifidobacter and fecal bacter, which produce butyrate, a short-chain fatty acid that is essential for maintaining a healthy gut wall. Additionally, it is mentioned that whey protein, which contains immunoglobulins, is particularly beneficial in tightening up the gut wall and reducing intestinal permeability. Casein There are two types of casein: A1 beta casein and A2 beta casein. A1 beta casein is found in many dairy products, particularly in the milk of Holstein cows, which make up 95% of the US dairy herd. This type of casein has a negative effect on gut permeability, causing an increase in intestinal myeloperoxidase and interleukin-4 levels, which reflect inflammation and gut permeability. On the other hand, A2 beta casein is found in the milk of goats, sheep, and certain breeds of cows, such as Guernsey cows. This type of casein has a neutral effect on gut permeability, with no increase in intestinal myeloperoxidase and interleukin-4 levels. Fermentation of A1 casein milk can break down some of the casein, but not completely, and may produce some beneficial metabolites that can compensate for the presence of A1 beta casein. However, it is not recommended to rely solely on fermented dairy products to avoid gut issues related to A1 beta casein. It is also mentioned that whey protein, which is found in dairy products, has a protective effect on gut permeability and can reverse gut permeability issues, unlike A1 beta casein. Omega-3 There are mixed reviews on how long-chain omega-3 fatty acids, specifically EPA and DHA, influence gut wall permeability issues. Some studies have shown that using fish oil, which is high in EPA and DHA, can be detrimental to gut permeability levels, particularly when taken in pharmacological doses. However, eating fish has been shown to be protective against gut permeability issues. Additionally, it is mentioned that the benefits associated with fish consumption are not seen with fish oil supplementation, and that researchers have found a pattern of dysbiosis and detrimental changes to the gut wall with regular fish oil consumption. Avoid ● A1 beta casein, a protein found in many dairy products, particularly in the milk of Holstein cows, which can increase intestinal myeloperoxidase and interleukin-4 levels, reflecting inflammation and gut permeability. ● Gliadin, a type of gluten found in wheat, which can cause a heightened zonulin response, leading to a breakdown in tight junctions and increased gut permeability. ● Fructose, which can favor the growth of pathogenic strains of bacteria, increasing gut permeability and inflammation. ● Polyunsaturated fats, especially omega-6 rich seed oils, which can disrupt the lipid raft model and make cell membranes more susceptible to oxidative stress and inflammation. ● Alcohol, which can cause increased intestinal permeability, and when combined with high levels of polyunsaturated fat and/or fructose, can have an exponentially greater effect. ● Glyphosate exposure, which can have immediate and dramatic effects on the microbiome, including the reduction of beneficial bacteria such as bifidobacter. ● Dysbiosis, or an imbalance of the microbiome, which can lead to increased gut permeability and inflammation. ● Stress, both physical and psychological, which can increase gut permeability and have downstream effects on overall health. ● Certain components in dairy foods, such as A1 beta casein, which can increase gut permeability and inflammation. ● High levels of omega-6 rich seed oils, which can disrupt the lipid raft model and make cell membranes more susceptible to oxidative stress and inflammation. Favor ● A diet rich in fermentable fiber from whole foods, such as whole vegetables, legumes, and berries, which can help support the growth of beneficial bacteria and reduce inflammation. ● Foods high in saturated fats, such as those found in sheep's milk products, Guernsey cow milk, and certain breeds of cows, which can help reduce gut permeability. ● A2 beta casein, a protein found in the milk of goats, sheep, and certain breeds of cows, which can help reduce gut permeability and inflammation. ● Whey protein, which can help reverse gut permeability issues. ● Certain nutrients and compounds, such as vitamin D, zinc, curcumin (found in turmeric), epigallocatechin complexes (found in green tea), and camphoral (found in coffee), which have been shown to significantly reduce gut wall permeability. ● A diet low in refined carbohydrates, sugar, and polyunsaturated fats, particularly omega-6 rich seed oils, which can help reduce inflammation and improve gut permeability. ● Foods with low carbohydrate densities, less than 23%, which can help reduce gut permeability. ● Phytonutrients found in whole vegetables, berries, and brightly colored fruits, which can help improve gut permeability issues. ● Resistant starch, which can't be digested by normal amylase activity and requires microbial fermentation, can help support the growth of beneficial bacteria and improve gut permeability. ● A diverse array of fermentable fiber, which can help support the growth of beneficial bacteria and reduce inflammation, and can be found in whole vegetables, legumes, and berries.

Respectfully, food isn't the primary influence on mitochondrial health. That role belongs to FULL-SPECTRUM SUNLIGHT, and humans are experiencing worsening health because of our indoor lifestyle under artificial light, especially blue light after sunset from our electronic devices. Yes, diet is important, but not even the healthiest diet will mitigate the harmful effects of our broken connection with nature. Eat well...but get outside, barefoot if possible.

Thanks for an excellent presentation - please keep them coming!

Fields of Sweet potatoes are sprayed with Glyphosate before placing the seed plants .

Great to see you back on TH-cam with a new video. I learn a lot from your presentations and explanations. kind regards miss Reimara

Tips, tricks, advice: ● Eat lower on the food chain: Eating lower on the food chain, such as sardines and mackerel, can be an effective way to get the Omega-3s needed. ● Use flax seed oil: Flax seed oil is a good source of Omega-3s, but it's essential to use cold-pressed versions. ● Avoid fish oil capsules: The efficacy of fish oil capsules is questioned, and it's suggested that krill oil might be a better choice. ● Choose the right oils: Avocado oil, olive oil, and almond oil have low levels of polyunsaturated fats and almost no Omega-3s, but they do not have large amounts of Omega-6s either. ● Wash produce, but it's not enough: Washing produce can help, but it's not an effective way to remove pesticides, as most pesticides are absorbed into the flesh of the fruit or vegetable. ● Use the Environmental Working Group (EWG) guide: The EWG guide can help people choose produce with lower levels of pesticides and herbicides. ● Eat organic and chemical-free produce: When possible, choose organic and chemical-free versions of staple vegetables and fruits. ● Strength training and cardiovascular exercise: Both types of exercise can improve mitochondrial density, but cardiovascular exercise is more effective. ● Intermittent fasting and caloric restriction: These methods can help improve mitochondrial health and biogenesis. ● Eat a balanced diet: A diet that is generally supportive of healthy mitochondria will also be supportive of anti-inflammatory processes. ● Avoid industrial seed oils: Some omega-6 rich industrial seed oils are associated with a heart-healthy diet, but they may not be beneficial for mitochondrial health. ● Give yourself an "oil change": Changing the lipid composition of mitochondrial membranes can be done through dietary changes, such as adopting an olive oil-based diet, which can lead to a 40-45% change in lipid composition after 30 days. Frustose: Fructose is a significant contributor to various health issues, including mitochondrial damage, insulin resistance, and obesity. Fructose is metabolized differently than glucose and that excessive consumption can have negative consequences for human health. Key points about fructose: ● Fructose is a biologically non-compatible macronutrient: Fructose is one of the most biologically non-compatible macronutrients in the human diet. ● Limited safe consumption: The safe ceiling for fructose consumption is around 25 grams per day for adults, with 10 grams per meal being a recommended limit. ● Different from glucose: Fructose is metabolized differently than glucose, and its excessive consumption can lead to the formation of damaging molecules like methylglyoxal. ● Consequences of excessive consumption: Consuming more than 50 grams of fructose per day can lead to consequences such as mitochondrial damage, liver health issues, increased body fat, and a higher risk of heart disease. ● Fruits and sweeteners are sources of fructose: Fruits, especially those high in fructose like mangoes and grapes, and sweeteners like high-fructose corn syrup, are significant sources of fructose in the diet. ● Athletes may not be exempt: While athletes may metabolize fructose more quickly, there is no evidence to suggest that they can tolerate more fructose without negative consequences. ● Methylglyoxal as a biomarker: Methylglyoxal, a byproduct of fructose metabolism, is being considered as a potential biomarker to track diabetes patients' progress and adherence to a better diet. Overall, the webinar emphasizes the importance of being mindful of fructose consumption and choosing fruits and sweeteners wisely to maintain a healthy diet. Mitochondrial health: Mitochondrial health is crucial for overall health, and a loss of mitochondrial function is linked to various diseases, including cancer, neurodegenerative diseases, renal failure, sarcopenia, and dementia. Mitochondria are damaged by excessive reactive oxygen species, lipid peroxidation, and environmental toxins, and that a diet high in omega-6 fatty acids, fructose, and industrial seed oils can compromise mitochondrial health. The webinar also highlights the importance of antioxidants, such as selenium, in protecting mitochondria from damage. Additionally, the speaker notes that certain lifestyle factors, such as exercise, intermittent fasting, and strength training, can improve mitochondrial health and drive the biogenesis of new mitochondria. Furthermore, the webinar suggests that a diet supportive of mitochondrial health should include foods that are rich in antioxidants, omega-3 fatty acids, and other nutrients that promote mitochondrial function. The webinar also emphasizes the importance of minimizing exposure to environmental toxins and pesticides, which can damage mitochondria. Overall, the webinar emphasizes the critical role of mitochondrial health in maintaining overall health and preventing disease, and provides guidance on how to support mitochondrial health through diet and lifestyle choices. Pesticides: Pesticides are a significant environmental exposure that can damage mitochondrial health. The speaker mentions that certain pesticides, such as rotone, parat, and chlorop pyos, can inhibit the formation of the antioxidant manganese superoxide dismutase, which is a crucial part of protecting the internal components of the mitochondria. Chlorop pyos, in particular, is highlighted as a damaging pesticide that can affect children's brains and mitochondrial health. The speaker also notes that choosing organic versions of fruits and vegetables that carry the highest chemical burden can help avoid exposure to these pesticides. Examples of pesticide-laden fruits that should be avoided unless organic versions are chosen include strawberries and grapes. Additionally, the speaker mentions that the Environmental Working Group (EWG) provides a resource that can help individuals make informed choices about produce, categorizing fruits and vegetables into "red light," "yellow light," or "green light" categories based on their pesticide levels. By choosing produce from the "green light" category, individuals can minimize their exposure to pesticides and mitigate their impact on mitochondrial health. AGEs: Advanced glycation end products (AGEs) are mentioned in the context of methylglyoxal, a byproduct of fructose metabolism. Methylglyoxal is described as a damaging molecule to human health and is considered an advanced glycation end product. It is stated that methylglyoxal has multiple effects on health, including contributing to diabetes, vascular health issues, and a loss of vascular elasticity. Additionally, it is mentioned that endocrinologists are looking at methylglyoxal as a potential biomarker to track a diabetes patient's progress or ability to adhere to a better diet. The Ketogenic Diet: The ketogenic diet is mentioned as a way to mimic fasting and promote the biogenesis or production of new healthy mitochondria. It is also mentioned that a ketogenic diet, like fasting, relies almost entirely on fat and ketone metabolism, which stimulates the body to increase mitochondrial density. Additionally, the ketogenic diet is mentioned as one of the non-exercise influencers that can improve mitochondrial density, along with intermittent fasting. However, it is also noted that there may be certain populations that are susceptible to seeing elevated TSH levels and lower thyroid activity when following a ketogenic diet, particularly with longer-term fasting. How to maximize mitochondrial health: ● Diet: Eat a diet that is supportive of healthy mitochondria, with a focus on anti-inflammatory processes. Avoid industrial seed oils high in omega-6 fatty acids, such as corn oil, sunflower oil, and soybean oil, and instead opt for olive oil, coconut oil, and avocado oil. ● Exercise: Engage in both strength training and cardiovascular exercise, as both can improve mitochondrial density. Cardiovascular exercise, in particular, can make major improvements in mitochondrial density. ● Intermittent Fasting: Practice intermittent fasting, which can stimulate the biogenesis or production of new healthy mitochondria. This can be achieved through time-restricted eating, such as eating within an 8-hour window and fasting for 16 hours. ● Ketogenic Diet: Consider a ketogenic diet, which can mimic the effects of fasting and promote the production of new healthy mitochondria. ● Reduce Chronic Inflammation: Chronic inflammation is a major driver of mitochondrial pathology, so reducing inflammation through diet and lifestyle changes is essential. ● Support the Microbiome: The microbiome plays a role in mitochondrial health, so supporting the growth of beneficial gut bacteria through diet and probiotics can be beneficial.

You're telling me I can't have three bananas two apples in a day? BS

Black Mulberries have high anthocyanin contents too.

When you do the gravity feed (without putting any pressure on the bag), what is the rate of mls per hour? My daughter's feeding rate is 300mls/hr with her pump. I'd like to match that somehow. Also, can the bag be hung for the gravity feed (to a stroller or carseat for example when on the go)

Thank you for your information. More awareness of this lind of thinking will help so many people.

Excellent information. Thanks for sharing.

missing so much. go back to school

Why people mention fruit juice in these videos?? Straight fruit is what we’re talking about?? Stay healthy ❤

You make a product that is very good and is blessed with all the nutrients necessary for human beings. Unfortunately, on this side of the world, more information is needed to be able to stay in touch and know that these things exist.

It is a beautiful story with which the entire project with which it is created is born....I, who am in Venezuela, would like to have more information and that you would publish information in Spanish so that another population that speaks Spanish or is Latin can access your products. I wish everyone understood the importance of food in life in the quality of life and that medicine should really be food and not a product created by pharmaceutical companies.

Nothing will ever become clear under an electron microscope. Antibiotics kill the bacteria in the mitochondria. If your body is kept in an iodine sufficient state, you will not need antibiotics. If you need to control bacterial growth, rather take higher doses of Lugol's iodine.

Wonderful presentation.

Its well known now. Reservatral is useless. It was the dye in sinclairs study that caused the benefits, not Reservatrol itself.

Absolutely incredible 🙌🙌🙌

This lecture is jam-packed with fascinating facts that certainly can build understanding and motivate us to take better care of our mitochondria and, thus, ourselves. Thank you! I’ll have this lecture on replay for sure!

The only way you can eliminate my inflammation caused by my immune system attacking my body, is if someone can take me out of this stress hell that my government is putting me through.

Surprising that western scientific knowledge is so lacking regarding health. But they are slowly learning these days.

Aronia berry aka choke berry and black raspberry very high!

Fructose=alcohol ?;

Plants are intelligent enough to realize that animals even exist? Which came first, the fruit or the animal.?

What a great presentation. I’m going to check out some of the papers this talk is based on! Such great science. Deserves manifold more views!

However that’s what you want for overall O6:O3, 4:1, so it’s not hurting you. Of course less than 4 would be better for gaining on the overall ratio.

How does connective tissue disorders contribute to this? What about having a hyper-sensitive immune system...mcas?

So we have pictures of disappearing tumors but seemingly little enthusiasm towards researching this diet.

Thanks s much. Excellent information here and very succinct.

Thomas, please do video on fructose and methylglyoxal. Just watched a video that said excess fructose can harm the mitochondria through the formation of methylglyoxal

Great stuff!

would have been useful to have a slide that has the recommended ratio, only flaxeed seeds was on the slide , what are the ratio for coconut oil and olive oil ? Would be better to have a list that meet 3-1 and 1-1 for layman ?

So lemons would be negative PRAL?

OMG you need to up the resolution on this and all future videos.

The idea that humans are carnivores is simply false. They found bits of dates and figs in the teeth of ancient humans in Europe. They certainly ate fruit.

Stevia was worse than sugar for me. Made me sick after trying it.

Dairy is hyperinsulinemic anyways. Should be mostly avoided.

Poor answer on organic pesticides. Consider the natural organic insecticide rotenone. You indicate it’s a mitochondrial toxin. It’s not about soil since this relates to plant nutrition. The answer should address what’s considered natural organic pesticides or those permitted for use by OMRI.

In my opinion as a Nutritionist- taking into account blood types (Rh+\_) because blood type O’s may not thrive long term with being a vegan or vegetarian successfully. It’s really rare and function or their blood (the cells- mitochondrion’s) may function differently in regards to what may work for that individual.

Humans only want A2 Jersey milk if you want dairy, but commercial milk products dont say. Find a milk share if legal or raw milk.