3:57 is there a mistake because it says transcription is going to be hard as there are stronger association of dan and histone but then you say the exact opposite?
Most people know nothing about molecular biology. This is not a video for the general public, but, rather, for that small percentage of the population who has the background knowledge to understand the subject matter.
Summary: Adding a methyl group to the tail (methylation) maintains the positive charge, making DNA more coiled and reducing transcription. Methyl group isn't positive. Adding an acetyl group to the tail (acetylation) neutralises the charge, making DNA less tightly coiled and increasing transcription.
@@MissEstruchBiology words such as Methyl. We give it an "eh" sound, whereas you place your accent on the "e". It is difficult to explain in writing. While I have your ear, if I wanted to convert a virus into a retrovirus, would I need to create an operon to code for my Integrase, Protease, and Reverse Transcriptase? It would seem I would need to insert an operator to allow repression until these enzymes are translated and ready to carry out their functions.
Glad you liked the video. Thanks for your point. For AQA that is the accepted the level of detail. As is often that case with science, GCSE and A-levels are taught at a particular level rather than all the exact details to prevent the courses becoming waaayyy to detailed and too high a standard.
Thank you!! You make this topic seem so simple now☺️
Thank you Leah :)
Glad you have found your 'subscriber choice' video helpful😁
Revision for next week yay
thank you so much, when i learnt this in school I was overwhelmed by the new vocab but you explained it perfectly!
Hello 👋🏻
That's great 😁 So pleased it helped you understand this topic and the key words
I was searching for a simple explanation on epigenetics and finally, i got it here.Thank you again
Glad it was helpful! Thank you
such a hard topic ngl
Oh my lawd im finished tomorrow
😂😂😂😂 how did it go
😂😂😂😂😂
Cry about it mate
Jesus is Lord btw 😁
3:57 is there a mistake because it says transcription is going to be hard as there are stronger association of dan and histone but then you say the exact opposite?
i return again to thank you, bless you! :)
You are very welcome! I hope the videos continue to help you.
hi I was wondering , if there’s decreased acetylation of histones does that make then bind to DNA Mir tightly or do they bind loosely ?? :)
i think they bind more tightly due to stronger association!
More tightly. The less acetylation, the more methylation.
Excellent videos, I am going to show this one to my AP Biology students. Given the quality of your videos, you should have many more views :)
Thank you so much. I hope it helps them.
Hopefully one day I will 😊🤞
Most people know nothing about molecular biology. This is not a video for the general public, but, rather, for that small percentage of the population who has the background knowledge to understand the subject matter.
@@gregorysmith1134lol this is just an a level biology video so for 16-18 year olds. And a lot of ppl do a level bio!
thank you doctor for this helpful video ☺☺☺
You're so welcome, hope I helped 😊
This was really helpful
Im finished for my mocks 😢
You have really helpful videos thanks!
So glad you find them helpful 😊
thank you
You're welcome 😊
Summary:
Adding a methyl group to the tail (methylation) maintains the positive charge, making DNA more coiled and reducing transcription. Methyl group isn't positive.
Adding an acetyl group to the tail (acetylation) neutralises the charge, making DNA less tightly coiled and increasing transcription.
Nice summary notes 😁
Like your British accent. You pronounce certain words differently than we do in America.
ahh yeah! Which words? I know in ecology niche is pronounced differently
@@MissEstruchBiology words such as Methyl. We give it an "eh" sound, whereas you place your accent on the "e". It is difficult to explain in writing. While I have your ear, if I wanted to convert a virus into a retrovirus, would I need to create an operon to code for my Integrase, Protease, and Reverse Transcriptase? It would seem I would need to insert an operator to allow repression until these enzymes are translated and ready to carry out their functions.
@@gregorysmith1134 smart guy
i’m praying this doesn’t come up tmr
Same bro
The acetyl group is not negative. It just masks the positive charge of histones. Anyway, your videos are awesome.
Glad you liked the video. Thanks for your point. For AQA that is the accepted the level of detail. As is often that case with science, GCSE and A-levels are taught at a particular level rather than all the exact details to prevent the courses becoming waaayyy to detailed and too high a standard.
if you're such an expert then why u watching bio videos
m lmk
thank you
you're welcome 😊