Topic 8 A level Biology - Learn the ENTIRE gene expression topic for A level in an hour!

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  • เผยแพร่เมื่อ 7 ก.ย. 2024
  • Learn or revise all of topic 8 (Gene expression) for A level biology. I talk you through the fundamentals, but you can watch my other topic 8 videos for the full, in-depth details.
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ความคิดเห็น • 140

  • @Ned24824
    @Ned24824 2 หลายเดือนก่อน +108

    crazy that im learning this for the first time the night before the exam

    • @chiamakaonwudiwe9141
      @chiamakaonwudiwe9141 2 หลายเดือนก่อน +10

      lmao same 😭

    • @cardboardleaf7971
      @cardboardleaf7971 2 หลายเดือนก่อน +5

      Yupppp

    • @sharons7540
      @sharons7540 2 หลายเดือนก่อน +12

      pulling an all nighter tn 😭

    • @glass1541
      @glass1541 2 หลายเดือนก่อน +5

      @@sharons7540SAME LOL

    • @scifigeek7207
      @scifigeek7207 2 หลายเดือนก่อน +2

      @@glass1541same here lmfao

  • @medicusv61
    @medicusv61 ปีที่แล้ว +237

    This HAS to be the hardest topic, I've been going through this video bit by bit for like almost a week now!

    • @fefunkey3808
      @fefunkey3808 ปีที่แล้ว +8

      Hardest?! I think this is the easiest!!

    • @medicusv61
      @medicusv61 ปีที่แล้ว +42

      @@fefunkey3808 Its easy content wise but ALOT of remembering. :(

    • @Idkchangethislater
      @Idkchangethislater ปีที่แล้ว +7

      Just boring mate module 5 and 6 mainly 6 are hardest

    • @Celeste_51
      @Celeste_51 9 หลายเดือนก่อน +7

      I agree hardest topic so far! (Apart from respiration oh my gosh)

    • @leoliversage
      @leoliversage 4 หลายเดือนก่อน +9

      @@Celeste_51 respiration easy compared to this

  • @lizzyharness4643
    @lizzyharness4643 ปีที่แล้ว +94

    for anyone here for tomorrows paper 2 don’t worry i will personally be lowering the grade boundaries for u 😍

    • @DoubleAAce
      @DoubleAAce ปีที่แล้ว +9

      Ill try by best to lower it even more

    • @dfszf4743
      @dfszf4743 5 หลายเดือนก่อน +3

      how did itgo

  • @beccaa7638
    @beccaa7638 2 หลายเดือนก่อน +15

    2:23 mutations
    6:52 stem cells
    9:08 transcription and translation
    18:28 gene exp and cancer
    25:46 using genome projects
    28:03 recombinant dna
    50:21 differences in DNA between individuals of same species
    54:40 genetic fingerprinting

  • @a1257_1
    @a1257_1 2 หลายเดือนก่อน +37

    Pray for me paper 2s tmrw and I’ve never even revised topic 6 or 8 before 💔

    • @MissEstruchBiology
      @MissEstruchBiology  2 หลายเดือนก่อน +5

      🙏🏻

    • @Ned24824
      @Ned24824 2 หลายเดือนก่อน +2

      GL bro

    • @rhysejohnstone4542
      @rhysejohnstone4542 2 หลายเดือนก่อน +5

      we need people like you for these grade boundaries

  • @Ned24824
    @Ned24824 2 หลายเดือนก่อน +28

    Im officially failing this exam tomorrow

    • @fibonacci3138
      @fibonacci3138 2 หลายเดือนก่อน +3

      In two hours omg!!! nah we're gonna smash it, god willing any examiners that mark my paper are extremely drunk

    • @saki7596
      @saki7596 2 หลายเดือนก่อน +1

      sigh for real, esp unit 6 lord

  • @ok6694
    @ok6694 2 หลายเดือนก่อน +49

    not looking good brev

    • @fatehkhan3524
      @fatehkhan3524 2 หลายเดือนก่อน +2

      Crazy, cuz everyone who liked was also watching it rather than revising

    • @rhysejohnstone4542
      @rhysejohnstone4542 2 หลายเดือนก่อน +3

      mums were cooked!

    • @fatehkhan3524
      @fatehkhan3524 2 หลายเดือนก่อน +1

      hows it looking now brev

    • @amogus830
      @amogus830 2 หลายเดือนก่อน

      ​@@fatehkhan3524 shut up b word

    • @fatehkhan3524
      @fatehkhan3524 2 หลายเดือนก่อน

      @@amogus830 blud who are you

  • @Hannibalsbreakfast
    @Hannibalsbreakfast 2 ปีที่แล้ว +72

    I honestly was looking for a video that sums up all of gene expression and here it all is >_< Thankyou so much

    • @MissEstruchBiology
      @MissEstruchBiology  2 ปีที่แล้ว +3

      awww perfect timing!!! Really hope it helps 😀

  • @jasminesfld7
    @jasminesfld7 2 หลายเดือนก่อน +9

    soo behind on this paper and i also have an english exam tomorrow😔dreading it

    • @ellad43
      @ellad43 2 หลายเดือนก่อน +2

      literally in the exact same position, i haven't revised at all for english today 😭hopefully we will both be fine

    • @ramengurung9913
      @ramengurung9913 2 หลายเดือนก่อน +1

      @@ellad43yeh same. Icl I’m cooked

  • @fibonacci3138
    @fibonacci3138 2 หลายเดือนก่อน +3

    Now time to procrastinate again till the night before paper 3

  • @poppydowse7753
    @poppydowse7753 2 ปีที่แล้ว +29

    thank you i hate this topic so much! by far the hardest!!

    • @MissEstruchBiology
      @MissEstruchBiology  2 ปีที่แล้ว +5

      Really hope it helps you learn to love it 😄

  • @tomconway8241
    @tomconway8241 ปีที่แล้ว +20

    You are a legend - this video is amazing, you have really simplified the topic for me!!

    • @MissEstruchBiology
      @MissEstruchBiology  ปีที่แล้ว +1

      Thank you!!!! So pleased it helped simplify it all for you 😀

  • @33helin
    @33helin 2 หลายเดือนก่อน +4

    don't know if i'll even scrap an E at this point please pray for me

  • @abcrm101
    @abcrm101 2 ปีที่แล้ว +40

    I have finished the whole series :)
    Time to do the same thing for chemistry
    P.s. thank you so much, you have no idea how much your videos help

    • @MissEstruchBiology
      @MissEstruchBiology  2 ปีที่แล้ว +7

      I'm so pleased you have found them helpful and wow for managing to watch all of them!!!

    • @abcrm101
      @abcrm101 2 ปีที่แล้ว +1

      @@MissEstruchBiology XD just a bit of time before and after meals

    • @elliesmith7518
      @elliesmith7518 2 ปีที่แล้ว +2

      What channel do you use for chem? Gimme rn

    • @sofiaqueen8635
      @sofiaqueen8635 2 ปีที่แล้ว +7

      @@elliesmith7518 allergy chemistry is really helpful :) he does a few exam boards and runs through all topics

    • @sofiaqueen8635
      @sofiaqueen8635 2 ปีที่แล้ว +3

      Allery* chemistry sorry ahah

  • @maheenarahman573
    @maheenarahman573 2 ปีที่แล้ว +37

    Thank you so much, I really appreciate your hard work :)

  • @shafinbepary2000
    @shafinbepary2000 ปีที่แล้ว +7

    the sheer dedication on this! kudo miss

  • @fibonacci3138
    @fibonacci3138 2 หลายเดือนก่อน +1

    Hi miss! at 47:00, are we meant to insert the enzyme gene into the plasmid? isn't it meant to be that the plasmid would already have the gene that codes for lactase and we're adding our DNA fragment to it to see if it disrupts the lactase? It does say that on the image you inserted but the text says otherwise... just checking with you if you see this!

  • @isobelcoulls9842
    @isobelcoulls9842 2 ปีที่แล้ว +7

    Thank you! I understand this a lot better now.

  • @benjaminhirschfield9164
    @benjaminhirschfield9164 ปีที่แล้ว +6

    great videos miss estruch, thank you for your help!

  • @noahblackwelll
    @noahblackwelll 2 ปีที่แล้ว +16

    For aqa is this literally everything we need to know

    • @MissEstruchBiology
      @MissEstruchBiology  2 ปีที่แล้ว +11

      Yes, it's all of the theory. It doesn't include application, required practicals or maths skills though.

  • @abcrm101
    @abcrm101 2 ปีที่แล้ว +12

    This series is awesome
    Thank you so much

    • @MissEstruchBiology
      @MissEstruchBiology  2 ปีที่แล้ว +1

      You're so welcome!!! Really glad you like this series

  • @theendoftimeandme6960
    @theendoftimeandme6960 3 หลายเดือนก่อน +3

    At 46:40 is it colourless to blue or blue to colourless?
    the text says from colourless to blue so thats why im confused
    thanks a lot for the vid btw, its a life saver 😭

    • @archiemarshall1533
      @archiemarshall1533 3 หลายเดือนก่อน +1

      from colourless to blue, if the fragment is present then it stays colourless as it stops the lactase gene, however if the fragment is not present then it will turn blue as the lactase gene will work

  • @lucyruddle8521
    @lucyruddle8521 2 ปีที่แล้ว +6

    Hello, thank you for this video! I have a question - at 36 minutes you talk about the modifications being made so RNA polymerase can work properly. Why is it RNA polymerase, not DNA? What is the RNA polymerase being used for? Thanks!

    • @stressedoutkid2415
      @stressedoutkid2415 2 ปีที่แล้ว +7

      DNA polymerase is used for semi conservative replication ONLY. whereas promoter initiates TRANSCRIPTION hence only transcription factors and RNA polymerase can bind to promoter. If DNA polymerase binds to the promoter it will technically inhibit the binding site of the promoter

    • @lucyruddle8521
      @lucyruddle8521 2 ปีที่แล้ว +2

      @@stressedoutkid2415 thank you, that makes sense!

  • @katrinabentley
    @katrinabentley 2 หลายเดือนก่อน +12

    i wanna scream 😊

    • @OnMyWayFive
      @OnMyWayFive 2 หลายเดือนก่อน +2

      relatable

    • @evolving_aura
      @evolving_aura 2 หลายเดือนก่อน +2

      same girl..

  • @footballvideoshd6183
    @footballvideoshd6183 2 ปีที่แล้ว +5

    I apologise that my comment is not related to this video. But I wanted to ask in regards to the ELISA test, which is explained in the Monoclonal Antibodies video. After adding the second antibody are you supposed to wash again to remove any unbound antibodies because I believe that that was not included in the method of performing the ELISA test

    • @vermillionxuxusss5801
      @vermillionxuxusss5801 2 ปีที่แล้ว

      Yea u wash after the second one otherwise when u add the substrate next it will break down regardless

    • @footballvideoshd6183
      @footballvideoshd6183 2 ปีที่แล้ว

      @@vermillionxuxusss5801
      How come that's not included in the video?

    • @alaynahurooj1995
      @alaynahurooj1995 2 ปีที่แล้ว

      @Veer Pattni thats in the immunity video

    • @MissEstruchBiology
      @MissEstruchBiology  2 ปีที่แล้ว +4

      Hello, yes you do wash after both additions. Hope that helps

  • @a1257_1
    @a1257_1 2 หลายเดือนก่อน +2

    Do we need to know the antibiotic resistant marker genes names?

  • @harrietrose347
    @harrietrose347 2 ปีที่แล้ว +5

    Hi, sorry this may be a stupid question but is oestrogen binding to a proto-oncogene to cause cancer just a completely random occurrence? Thank you for making these videos as well they are really helpful:)

  • @jeffreylau2010
    @jeffreylau2010 2 ปีที่แล้ว +6

    To clarify: When do you use DNA polymerase or RNA polymerase? (how to remember the difference?)
    (Might be a good TikTok video)

    • @MissEstruchBiology
      @MissEstruchBiology  2 ปีที่แล้ว +6

      DNA polymerase = for DNA replication
      RNA polymerase = for transcription
      Hope that helps 😊

  • @jessmitchell3195
    @jessmitchell3195 2 ปีที่แล้ว +2

    Great video! For the marker genes, I though that if the plasmid was taken up by the host cell then they will express GFP or they will be resistant to the antibiotic as they contain the marker gene (instead of disrupt the gene so it isn't expressed) or is it the opposite way round?

    • @MissEstruchBiology
      @MissEstruchBiology  2 ปีที่แล้ว

      Hey its the opposite way round, as explained in the video..However, read the exam questions carefully to see the information given on where the DNA fragment is inserted.

  • @yousifmajeed9316
    @yousifmajeed9316 2 ปีที่แล้ว +4

    thanks for this

  • @sams582
    @sams582 2 ปีที่แล้ว +1

    at 46:26 how do we know that the bacteria which aren't fluorescing even took up the plasmid at all

  • @bobbytoot9858
    @bobbytoot9858 2 ปีที่แล้ว +4

    how much of this is included in the advanced information?

    • @MissEstruchBiology
      @MissEstruchBiology  2 ปีที่แล้ว +3

      Quite a lot. Gene expression is on paper 2 and gene technologies on paper 3

  • @katieweymouth3103
    @katieweymouth3103 2 ปีที่แล้ว +3

    hi miss, what unit will you be uploading next?

  • @stormblaster6781
    @stormblaster6781 2 หลายเดือนก่อน +1

    Omd this again 😭😭😭😭

  • @atrappy2077
    @atrappy2077 2 ปีที่แล้ว +2

    topic 5 next please

  • @samimuhammad1201
    @samimuhammad1201 2 ปีที่แล้ว +2

    Nice video

  • @rainbowraider5029
    @rainbowraider5029 ปีที่แล้ว +2

    is this ok to use for edexcel b

  • @jess1148
    @jess1148 2 ปีที่แล้ว

    you're amazing thank you!!!!

  • @yabombo8145
    @yabombo8145 2 ปีที่แล้ว +1

    Cheers lad have a good en

  • @doodlebob1898
    @doodlebob1898 2 ปีที่แล้ว +2

    Hi miss can you do all the other topics you have not done

    • @MissEstruchBiology
      @MissEstruchBiology  2 ปีที่แล้ว +1

      Hello, yes 😊 I'm doing one per week

    • @doodlebob1898
      @doodlebob1898 2 ปีที่แล้ว +2

      @@MissEstruchBiology ty

    • @robyntappern7637
      @robyntappern7637 2 ปีที่แล้ว +2

      @@MissEstruchBiology hey Miss thank you so much for your videos, which topic will you be doing next?

    • @MissEstruchBiology
      @MissEstruchBiology  2 ปีที่แล้ว +2

      @@robyntappern7637 I'll put it to a vote!

  • @soph2809
    @soph2809 ปีที่แล้ว

    in 46:36 what if it isn't glowing because it hasn't taken up the plasmid? sorry

  • @ta647
    @ta647 ปีที่แล้ว

    hi miss, do aqa students not need to know about gene therapy?

  • @vermillionxuxusss5801
    @vermillionxuxusss5801 2 ปีที่แล้ว +5

    I got an idea, how bout you make a video for each paper with only the stuff on advanced information

    • @MissEstruchBiology
      @MissEstruchBiology  2 ปีที่แล้ว +11

      haha its like you've seen my diary! That's coming in a month

  • @AjayPatel-xv4dk
    @AjayPatel-xv4dk ปีที่แล้ว +1

    MediiiiCoach getting the recognition

    • @saddish2816
      @saddish2816 5 หลายเดือนก่อน

      Did u manage to sleep with any white girls in uni?

    • @basset5889
      @basset5889 3 หลายเดือนก่อน

      @@saddish2816 huh

    • @saddish2816
      @saddish2816 3 หลายเดือนก่อน

      @@basset5889 ?

  • @radhaxel
    @radhaxel ปีที่แล้ว +1

    is this for aqa?

  • @mariambenafia1385
    @mariambenafia1385 2 ปีที่แล้ว +1

    Topic 2 next? Or 4

    • @MissEstruchBiology
      @MissEstruchBiology  2 ปีที่แล้ว +1

      Potentially 2!

    • @atrappy2077
      @atrappy2077 2 ปีที่แล้ว +1

      u not interested in topic 5? makes up a lot of paper 2 and paper 3....

  • @chunkplunk
    @chunkplunk 2 ปีที่แล้ว +7

    this looks painful

  • @ludicrous_doughnut3533
    @ludicrous_doughnut3533 6 หลายเดือนก่อน +1

    no timestamps 💀

  • @Elias.04
    @Elias.04 ปีที่แล้ว +5

    Gene technologies is easily the worst topic 🥲

    • @MissEstruchBiology
      @MissEstruchBiology  ปีที่แล้ว +3

      it's a tough one!

    • @Elias.04
      @Elias.04 ปีที่แล้ว +1

      @@MissEstruchBiology You make it easier though, thank you so much 🥰

  • @pastaslut
    @pastaslut 10 หลายเดือนก่อน

    This is actually so so helpful thank you so much!

  • @samimuhammad1201
    @samimuhammad1201 2 ปีที่แล้ว +3

    Nice video