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Thanks for the video. I too feel that Dr Sinclair needs to explain the letter. He is aware of the uproar this has caused within the anti-aging community and we do deserve an explanation. I am grateful for the years of research he has done to get were we are today and value his opinions. It's time that he speaks up. Wishing the best to your wife.
Thank you Nancy. Some people don't realize I've made this video for you, for our community. Sinclair's company (which he confounded, hence "his") filed a request to activate the preclusion provision of section 201. Meaning, a request to stop the sale. It already happened. And the FDA already sent a warning letter to abide. We have 4 historical examples (of section 201) of what happens in those situations. This is the time to put public pressure on his company. The FDA won't follow through if his company won't go further. The only unknown here is what role or control Sinclair himself has in this situation. And I clearly stated, repeatedly, that we don't know. I'm taking here personal risks myself to support our community. To put me forth like this.
I'll explain it for him. His company (he?) knows that by filing the IND that by law prevents the retail over-the-counter sale of the thing that is the subject of the IND, and will do so for much longer if the thing gets FDA approval as a drug. His company is spending money on research o get it approved as a drug, and wants to make money eventually. If they don't present research regarding the drug's efficacy, doctors won't prescribe it for various treatments, and drug companies and governments won't provide it for particularized uses. This is unlike NAC, for which the FDA. approved exclusive uses as a drug have long ago expired. So when, if, NMN comes off the shelves, just switch to NR, which is more effective by weight than NMN anyway. NMN is NR (Nicotinamide riboside) with a phosphate molecule attached. The phosphate molecule make Non to large to enter the NR kinase pathway into a cell. So, if NMN is taken orally, it has to cast the phosphate to enter the cell as NR. It then pickup a phosphate molecule intracellular, and converts bac to NMN, and then the nd product - NAD. And no, thee is not a dedicated kinase pathway for NMN to enter a cell intact.
The upside of a drug company testing a drug that might reverse Alzheimers and Freidreich’s Ataxia is they have the money to do high quality research, and if their research shows that the drug works, the number of people who take NMN will be many, many times greater than it is now.
Thanks Rimon for your analysis. I was a big Sinclair fan until the sale of Resveratrol controversy erupted. I have become much more skeptical of his motives.
As a holistic doctor I’m disappointed at this point in time. I share your thoughts and feelings. My suspicion is that NMN may work as well as or close to as well as the new potential drug. So it appears to be a money thing for company and investors that could charge $$$$$ for the drug compared to $ that NMN cost. And do they really want to help the great number of people with NMN for $ ????? It’s not about safety to ban NMN. And if we are well with NMN the new drug would possibly not have the selling point they could get with the drug.
If you dont want to used its your choise....But NMN is a very good product and I think that is good to use, and dont bay antybiotics or other drugs. Everything is money...to be in the good health of course is for rich people. But nobody work for fee...Normal...I use NMN and Im very good health. Im 75 years old. HMN from Zarapharm. Bye
Dallad don't give up yet! Sinclair may have been naive a bit and could have lost control. He could be the same person you think he was.... just a bit naiver than might have imagined.
The US pharmaceutical industry is horrible and ruthless. How much of this is Sinclair vs pressure from his investors. Pharmaceutical research is very expensive. He might still be the good guy in all of this, but it may not matter. There does need to be a large public outcry in which politicians are getting pressure from their constituents and unfortunately competitor companies paying lobbyists to influence legislation. Informative video thank you, it gives me hope. I just got tinnitus and hearing loss due to aging so I was hoping NMN could help.
Hi Turk Nice to meet you. I guess I'm too rooting for Sinclair to convince us that he lost control over his company and now he will try to make amends.
Sometimes tinnitus is caused by cranial nerves being compressed as they pass through the skull. This results from chronic nutritional deficiencies of minerals and bone-building nutrients. Typical MD's will not be able to help you. Treating the symptoms will never address the causitive factors of the problem.
I recently came across your Channel and love the work you do for this longevity Community. I've been following David Sinclair for a while, including Dr Brad Standfield. I've watch a few of your videos and like the deep information you give us, about David Sinclairs supplement stack and intake. I am worried about the NMN Ban and hope he comes out to speak on the Subject.... I just hope he isn't going against the Longevity Community!
Nice to meet you. I'm like you. I guess I'm rooting for Sinclair to convince us that he lost control over his company and now he will try to make amends.
My husband, 74 and I 67, have both taken NMN and before that NR. Because we also changed our diet to low carb with intermittent fasting and supplementation with various specific vitamins so I can't say specifically that the NAD precursors made a difference. We started with Dr. Gundry's products, then felt like we were getting snake oiled. I still believe that Gundry has his finger on the pulse of longevity research but he's trying and is making a fortune. We tend to think if a researcher makes money from his research he's a sell out. But wouldn't anyone want to profit from his life's work?
Thanks for your courageous speaking! I totally agree with you! I feel the pain of be abandoned from a beautiful mind. I hope not! I love Sinclair too a lot. ! My love to you and your people!
NNM an NR do the same thing. If NMN becomes hard to find, switch to NR. The problem with these molecules, is it is very hard for them to be absorbed in large enough quantities to be effective.
Nmn has greatly improved my energy. I have hypothyroidism and a neurological autoimmune disease. This is the only supplement that has ever helped improve the quality of my life including pharmaceutical medications or other supplements.
Thank you for seeing me Monica. I'm taking here personal risks myself to support our community. To put me forth like this. Some people don't realize I've made this video for you, for our community. We have 4 historical examples (of section 201) of what happens in those situations. This is the time to put public pressure on his company. The FDA won't follow through if his company won't go further. This is the time to put pressure on them. This is why I've made this video.
@@WellnessMessiah Hi Rimon, could you please share the best doctor or treatment for your lovely wife ,my youngest brother has similar issues and I am looking for a good specialist, it's really hard to find one ?! Greatly appreciated 🙏🙏🙏🙏😍👍❤
I’ve been on the NMN train forever but lost confidence in Sinclair when I started to do more research from years ago around him being a cheerleader for resveratrol and then him dying his hair, getting Botox injections and using a beautification filter whenever he’s doing videos.
Not true. He knows very well about the turmoil it’s causing. If it was done in line with his objective to make things better for everyone, responsible and honest reaction would be to step out and explain that in the light of new development. Why wouldn’t he in that case? If his objective is self-profit - then the most sensible thing is, of course, to keep silence, at least that will - may be - keep ppl guessing.
Does it? What's it saying then? I thought silence gave you no information and if there was any hypothesis gained for my silence it would have a narrative or bias
It wouldn’t if David wasn’t such an outspoken, public figure with his social media, podcasts, IG feeds where he clearly projects himself as a scientist whose goal is to make the world a better place, cure disease of age, reduce epigenetic test cost for ppl, he makes a point that he is not for-profit and doesn’t affiliate himself with any NMN brands and so on….so yes, in the light of these statements, his current silence is inconsistent and is, in fact, an action in itself.
Even asking for “protection against competition” in a free market is a D move, but in the case of a longevity substance…even more so. David Sinclair has revealed himself as an almost cartoonish corporate villain, like the dude in Total Recall who monopolized oxygen on Mars and then charged people to breathe.
Totally agree with your assessment on the general state of supplements after the NMN band attempt by Sinclair's cofounded company. I use to listen to Sinclair for a long time. Now I believe he is just another $ hungry entity like any other drug producers. I am done with him and discard his lame letter trying to distance himself from the company that is promoting the band NMN.
Adding to the absurdity is that David Sinclair has said in past interviews that he doesn't have a prescription for Metformin, but rather sources it from countries that don't require one.
I appreciate this video and you wanting to be fair. I am far more skeptical of Sinclair's motives given his involvement in the Resveratrol GlaxoSmithKline fiasco. If he walks like a duck, and quacks like a duck, he is certainly not an eagle!
In my country, Estonia, selling NMN has been banned long ago. It is explained away as novel dietary ingredient with unknown effects, with unkown safety.
Update: the FDA has requested that companies stop production of NMN supplements as of Dec. 7, 2022. Companies still can continue selling, but the FDA can stop NMN sales anytime now.
Best lesson learned is to never substitute facts and reality with cult-like beliefs surrounding a single person. Especially when the person has a prior history of similar money-first ambitions with the science he promotes.
I just wonder, now I can get Tylenol or Aspirin in Amazon and my local pharmacy. Could it be that in the future, NMN may be available without prescription in my local drug store, not in my health food store.
Hi Emilio, I'm no optimistic about that. Most of these drugs used to have patent , established as a drugs for 2-3 decades, and only then when it's expired you had this status. It's a long way for NMN to go.
The FDA and David Sinclair should be ashamed. There is a higher judge we will all meet and be judged by one day. How dare they try to take away a nutritional supplement that so many people need. I would protest this ban.
Just my 2 cents on NMN, I'm in my twenties for reference so maybe I'm young for someone taking this. I personally feel like its one of the few supplements I've taken that I've noticed a real tangible difference before/after. I take 250mg liposomal non once a day most days. When taking it I feel a general feeling of well-being and energy like I had a really good night sleep. Perhaps its a placebo effect? Hard to say to be honest. But I feel Its been good more me after taking it for 2-3 weeks
A tweet came from Dr C. Branson saying may be NR may cause cancer & some others there to discuss,have a look at the tweets if you like😞 I saw on 11 Now after Midnight.it's scary. Xxx
Agree 100% with you ad all your arguments. I would be very very SAD if the excellent Saint Clair turns out to be just another BAD. I hope that such is to the case. Please come out Saintclair ad speak out.
I wonder how difficult would be import NMN to Mexico from the same lab that Donotage gets its NMN. In Mexico is so easy for companies to obtain their licence. However nobody knows NMN. But people love their supplements and more in my city. We even have our own Herbalife Mexican version. Any enterprise in Mexico though sounds very dangerous.... However there are a lo of wormholes. An example, our Social healthcare system is stuffing our people with metformin, may be because we are fat.
I am so glad that you put out the information about supporting you I’m going to join that and support you and my best to your wife in every way you’re a good man I really admire that you’ll be hearing from me soon
My ailments are chronic, and so get better and worse and better and worse. I can never tell with any degree of confidence whether a supplement is heping or hurting.
What is wrong with you? My husband has got ataxia, and it doesn't help but it doesn't harm it is just the same. What I do know it that when he was young he could walk with no problem.
@@cynthiacovarrubias7096 Sorry about your husband’s difficulties. I still take a whole bunch of supplements in the hopes that some will be helpful even though it’s hard to tell when a supplement is helpful.
@@gabymalembe Eat magnesium and potassium and fiber- heavy food. These minerals balance out calcium that may over-signal heart muscle - also incorporate more calcium-channel blockers in food - ginseng, turmeric, olive leaf estract are Ca+ channel blockers, just to name a few, there is tons, usually in plant food. Avoid meat-heavy food and refined. Hawthorn extract act more through other mineral channels but also beneficial. More indirect effects would be through beta-adrenergic receptor blockers (beta-blockers for short) - hawthorn has indirect effect there as well, as well as magnesium and curcumin that lower stress hormones that act on beta-receptors. In recent times, spike proteins from biological weapons destroy gut bacteria - ths in turn has effect on vascular health. So keep the gut healthy - eat fiber (not huge amounts when not used to yet), fermented food (not huge amounts when not used to yet), turmeric and resveratrol, omega-3, absinthum species plants, oregano, many other spices control the pathogens in the gut (you might not feel them grow but the effect is through immune and inflammatory processes in the body) - gorwing healthy gut flora takes time and all of the treatments (curcumin, NMN, resveratrol, phytoestrogens in soy, flax seed) act through bacteria first metabolizing the components - so the changes take time for months or few years - don't expect quick changes - common mistake people make is that they expect quick changes to chronic conditions, BUT the conditions are coupled to very long acting microbial changes.
Thank you for seeing me. I'm taking here personal risks myself to support our community. To put me forth like this. Some people don't realize I've made this video for you, for our community. We have 4 historical examples (of section 201) of what happens in those situations. This is the time to put public pressure on his company. The FDA won't follow through if his company won't go further. The only unknown here is what role or control Sinclair himself has in this situation. And I clearly stated, repeatedly, that we don't know.
@@WellnessMessiah I hope you are successful & we can continue to use this ‘vitamin supplement’. I’m in Australia & hope our equivalent regulatory body doesn’t follow the FDA.
The new drug formula has not been announced yet and I am wondering if the NMN ban is because maybe the drug is a formula of NMN and another substance that increases NMN, like Apigenin or something similar that hackers can sell the NMN and the additional substance separately. If the new drug is a more crystalized form of NMN then the company has nothing to worry about.
It is time to start a petition to stop the over reach of the FDA trying to require a prescription for NMN. 35 years ago we petitioned to stop the FDA from taking control of vitamins and supplements and of course making them more expensive. Requiring doctors to prescribe NMN is not really a viable option as doctors are only required to take 1 class in nutrition and information online is more up to date than the doctors! Please petition!
Sinclair knew what he was creating and aggressively created a demand to remove it from the market to control supply. He did it years ago when his company released, removed, re-entered resveratrol then sold it for $720M. It's all about the money. There's no ethic attached to his work. Pisses me off.
Correct me if I'm wrong, but a banned supplement is different from a "controlled substance" drug right? Like is would still be possible to bulk purchase nmn powder marked for science use I'm pretty sure.
Dr. David Sinclair has a conflict of interests. He is connected to that company. Pharmaceutical companies want to maximize PROFITS above all else. Dr. Sinclair's highest priority is maximizing his profits and career FIRST. I do think he cares about human health, but that's secondary to his career and profits.
I say he has been forced, i have been taking nmn for 2 weeks and i am blown away how much energy i have, my eye sight is better and i think more clearly. I am 55 years age....🙏
Being 1000 times more potent is not in itself a large benefit. The proper metric is a cost-benefit curve. Unless their new drug pushes that cost benefit curve out in some way, whether reaching benefits impossible for NMN to reach, or reaching the same benefit more *economically*, the increasing potency doesn't matter. We're currently talking about a gram of NMN as the scale of a dose. 10 grams, a tenth of a gram, who cares? If the *optimal* dose is in that range, with the optimal dose for his drug simply scaled smaller because of potency, then I'll take the more economical of the two.
1st of all, on reading Sinclair's book where he seems to say "all of these longevity discoveries are for you, the general public" a suspicious bell went off in my head. These discoveries are for the people who can pay, & they are for the financial benefit of those working on the discoveries. In other words, longevity through chemistry is for the wealthy. That's a no brainer. But the disgusting aspect of all this, is to take a substance, like NMN, which was not invented by Sinclair, et al, and which is already being used by the public, and designate it for exclusive use by a company who intends to make big bucks off of it is pure corruption. But that's the unwritten role of the FDA, protect drug company profits.
This is nothing new for Sinclair. A few years he popularized resveratrol as a potent anti-aging substance. He then started a company that allegedly had a far more potent form of resveratrol, but it was a drug. The company was then sold for $720 million, but the drug turned out to be an abject failure and was never released. Sinclair is a scientist, but he is also an opportunist, and I question his motives. No legitimate scientist who studies aging would suggest that it was a disease that has a cure, as Sinclair does all the time. A lot of people put him on a pedestal because of his frequent outlandish statements, but those who are rational and have a knowledge of how true science works know better.
I wish my husband could have taken nmn after his stroke. Why don't doctors perscribe this? Neither the VA or outside health system mentioned this supplement to us, I am very sad.
Great video. Thank you. Sinclair is decent, honest and very naive. He had no choice but to fall in the trap of criminals, hungry for money Jorge A. Carpio, MS, PE
It could very well be Jorge. He could be naive, That's my feeling too. My goal in this video is for his company team to watch as well. We have 4 historical examples (of section 201) of what happens in those situations. This is the time to put public pressure on his company. The FDA won't follow through if his company won't go further. The only unknown here is what role or control Sinclair himself has in this situation. And I clearly stated, repeatedly, that we don't know. I'm taking here personal risks myself to support our community. To put myself forth like this.
Not surprised if we find out that NMN doesn’t help… When money is involved, be aware. Supplementation on basic minerals missing in our food is your best bet!!!! Only thing I have seen a noticeable difference on my energy level .
Yes, this makes no sense at all. And it makes me VERY angry. I don't want to go on a rant but this offends me in so many levels. Denying people autonomy over their bodies is evil especially when it affects their health. I've taken NMN, which I first heard about from Sinclair, for about two- three years now. It has made a HUGE difference in my well being and the prospect of losing access to it is awful. And for you it is even worse because of your wife. You should have access to all treatments to help her! But that's where I stand right now. This sucks and I'm angry. On a brighter note, I've recently found a good supplement that I think will activate SIRT6! I'm very excited about it!
Hi Jason glad you've found it. My goal in this video is also to put pressure on Sinclair's company. I suspect he lost control a bit. If they won't follow through, the FDA won't ban it.
I wrote my representative just a day ago. I haven't heard back yet but I believe she will do what she can as she is not one of the power hungry , money grubbing pigs. She is a true patriot and a person of the people.
yes Eh Eh, I'm doing my part here. We have 4 historical examples (of section 201) of what happens in those situations. This is the time to put public pressure on his company. The FDA won't follow through if his company won't go further. In addition, the FDA doesn't decide everything and it can go to upper courts. Not yet, the iron is hot. My goal is for his team to watch this video too. And him. I'm taking here personal risks myself to support our community.
I keep on sending my prayers to your beautiful wife. You are a unique person & sure God will award you🙏🌹🙏🧿🧿🌹 Thanks for sharing your Resveratrol dose, I dropped it after your one of the podcasts. Today gave me the chance to confirm it after sharing your dose. Every other day 200mg around, I take. I don't have a smaller spoon than this😉🙏⭐💛🎄💛🦌✨ We’ve loved our Valuable Scientist but maybe he didn't care about us that much😞 But he'll respond to you, I'm sure. Also, I laughed at a commend, under one of his latest podcasts, A follower Saying, " please let “Regular “people keep on buying NMN, don't ban them😂😂😂 God Bless you & your wife🙏🙏🧿🧿
Dear Rimon, Thanks for reading my comment . Nice to see you full of hope again🙏⭐💫✨ I hope All goes well 🙏 Hope your & our Valuable Scientist give more advice about your beautiful Wife's situation to you🙏😞 He must be busy or maybe his character is different🤔like my son's. What I meant is; This type of different soul is determined to do things in their own time, you can't push their cause, Once they've been broken in the past😌 they have their own rules, ego's now. I live 5 min away from my son but sometimes he calls me back after I got well😅😅😅 They are too busy with their business life and their phycology🤯is always up & down😞😞😞 Looking forward to hearing about your next video. Whatever you share it's valuable to me. God Bless you & your Wife🙏🙏🧿🧿
To give a product that is so helpful to so many people and actually promote it … and…. Then take it away is worse than cruel. Who’s influencing you David Sinclair?
Hey Rimon :) Regarding your wife and stroke - have you looked into the potential benefits of methylene blue for post stroke? Its impressive. Many other benefits that are pretty mindblowing too. Wishing you and your loved ones the best my good man ❤
Is it possible that Dr. Sinclair is deferring to the government or, and affect deflecting so as to avoid blame or responsibility and still maintain profitability for himself and his investors? On another note I sent prayers and hopes out for your wife’s health as well as yourself and I appreciate you posting this video it is very interesting and a little heartbreaking that so many people will be adversely affected by what in my estimation is the creation of a monster
You guys really didn't see through his charade? It was pretty obvious from the beginning that he is involved in some high stake games. It is shitty what they are trying to do. But i am not surprised in the least.
It's just so bad. I understand someone wanting fame and fortune. But why should people want more than 200k a year on tenure? I mean, if you're somewhat cautious with spending you can retire at 55.. And then just ask money for interviews or for endorsements and maybe speed up the earning process. I do understand that people want even more than that. But never enough when it doesn't benefit the greater good? That's just rubbish.
Thank you for seeing me Steven. I'm taking here personal risks myself to support our community. To put me forth like this. Some people don't realize I've made this video for you, for our community. We have 4 historical examples (of section 201) of what happens in those situations. This is the time to put public pressure on his company. The FDA won't follow through if his company won't go further. The iron is how now. The only unknown here is what role or control Sinclair himself has in this situation. And I clearly stated, repeatedly, that we don't know.
I noticed also, that he was not looking as healthy as he did prior to the vegan food switch. I hope he goes back to a more balanced diet so he can regain his healthy glow again.
Real innovation is not for YOU or me. Its for the elite. Michael Jackson was doing hyperbaric chambers in the early 80´s when we were hearing about it 20-30 years later (he was hardly elite, but rich with connections). Our access to Chat GTP is the low-end tech. Its much more advanced- but not for US.
Did Sinclair's company head off a reported IPO for a longevity capsule in February 2023, where Bezos of Amazon, Thiel of PayPal and Rockefellers have reportedly invested $US100 million? Note, this occurred after Amazon banned NMN in January 2023. Sinclair, as a researcher rather than an investor, may have vacated the conversation to enable his company to address this possible competitor.
Daivid Sinclairs business is developing new medicins. As I understand what he said is that he has asked FDA to regulate NMN. That is not the same as banning it. Now the FDA may have rules in regards to this request and that may be to stop selling NMN over the counter until it can be regulated or be denied regulation. Anyways there are at least one company out there who sells NMN as a chemical and not as a supplement. A ban should only apply to supplements so even the Americans should be able to get around this if it happens.
Boils down to da MONEY ! Just like STATINS their cost to the cost of niacin which does basically the same but one is prescription the other over the counter , and many other drugs that are prescribed but can find alternative over the counter , If Sinclair has found a more effective product than that of nmn then the obvious thing to do is like any other competitive product either purchase the rights or find a way to prevent the consumer from using it and then PROMOTE your product at YOUR price ! So if investment in new product and new product better than the previous one and want a return on the better product and your the sponsor of the previous one , and still save face ! Then have the FDA BAN it for you ! Not your fault ! But hey got something better for my loyal consumer ! But the FDA Has to Approve It First and then NOT my FAULT but it going to be by prescription only ! and at HIGHER PRICE ! Not my Fault ! I love people ( money ) ! Investments and investors are there for PROFITS, Squeeze and SQUEEZE ! Then once the FDA bans nmn then those who had faith in humanity will be at the mercy of a prescribed product that would have to be given from a person that would make the decision if you are WORTHY of using this product and at the same time the person that prescribed you the product is looking younger all the time ! Or the FDA may ban the old product and the new product for the consumer and. Allow it's use for research only ! Just like the substance Trodusquemine discovered in cancer research and found with one treatment in mice it CLEARED ALL CHLOSTEROL PLAQUE in their little mouse body ! Now since Heart Disease is a Main killer How would Trodusquemine have an impact on saving human life ? BUT by the FDA it is BANNED for consumer but ALLOWED for RESEARCH ONLY ! WHAT ? WOW ! GOOGLE IT !
Sinclair only cares about money. No doubt NMN improves health but Sinclair dyes his hair, wears make up and has a state of the art lighting, camera and filters. I never trusted him and now he shows his true colours.
please stop blaming the man for working, he has bosses that funded his research and probably by contract must do as bid anymore than I blame the newscaster for spewing garbage elected for that days broadcast by his bosses, he gave his views on everyone living longer so I am fine with that, am glad he did the work, got the message out in time so we can take the blame were it belongs, the elitists, the rich and government that would use such an affordable supplement for jacking up the price and "reducing the surplus population", the last of their choice of course
are we jumping the gun here? we haven't heard from Dr. Sinclair's side of the story. and another thing is Dr. Sinclair's job is to find a way to cure aging, he doesn't have to explain his action to anyone. you'll never get anywhere if you have to explain everything to anyone who questions your action.
Great question unbox. It's not jumping the gun at all. Sinclair's company (which he confounded, hence "his") filed a request to activate the preclusion provision of section 201. Meaning, a request to stop the sale. It already happened. And the FDA already sent a warning letter to abide. We have 4 historical examples (of section 201) of what happens in those situations. This is the time to put public pressure on his company. The FDA won't follow through if his company won't go further. The only unknown here is what role or control Sinclair himself has in this situation. And I clearly stated, repeatedly, that we don't know. Some people don't realize I've made this video for you, for our community. And for his company's team to watch. I'm taking here personal risks myself to support our community. To be put forth like this.
All Sinclair is trying to do is to clean up the supplement market with all its bad NMN products. When that’s done, he will come back with a safe and working NMN product. I think that’s awesome.
clicK bait no such thing as stated extsts. Author of video says so in first sew seconds. Sinclair appeared a day later and was not concerned at all. did not hear of it (Because it did not happen).
David Sinclair is committed to longgivity but don't forget David is a fine Jewish Businessman, who by design is trained to prioritise profits above everything else.
Sinclair has always been about the money - how many millions did he make off of his resveratrol investment before the company abandoned production? en.wikipedia.org/wiki/Sirtris_Pharmaceuticals
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Sinclair is clearly MUCH more of a self-serving businessman than a humanitarian and researcher. He has revealed himself.
Thanks for the video. I too feel that Dr Sinclair needs to explain the letter. He is aware of the uproar this has caused within the anti-aging community and we do deserve an explanation. I am grateful for the years of research he has done to get were we are today and value his opinions. It's time that he speaks up. Wishing the best to your wife.
Thank you Nancy.
Some people don't realize I've made this video for you, for our community.
Sinclair's company (which he confounded, hence "his") filed a request to activate
the preclusion provision of section 201. Meaning, a request to stop the sale. It already happened.
And the FDA already sent a warning letter to abide.
We have 4 historical examples (of section 201) of what happens in those situations.
This is the time to put public pressure on his company. The FDA won't follow through if his company won't go further.
The only unknown here is what role or control Sinclair himself has in this situation.
And I clearly stated, repeatedly, that we don't know.
I'm taking here personal risks myself to support our community. To put me forth like this.
I'll explain it for him. His company (he?) knows that by filing the IND that by law prevents the retail over-the-counter sale of the thing that is the subject of the IND, and will do so for much longer if the thing gets FDA approval as a drug. His company is spending money on research o get it approved as a drug, and wants to make money eventually. If they don't present research regarding the drug's efficacy, doctors won't prescribe it for various treatments, and drug companies and governments won't provide it for particularized uses. This is unlike NAC, for which the FDA. approved exclusive uses as a drug have long ago expired. So when, if, NMN comes off the shelves, just switch to NR, which is more effective by weight than NMN anyway. NMN is NR (Nicotinamide riboside) with a phosphate molecule attached. The phosphate molecule make Non to large to enter the NR kinase pathway into a cell. So, if NMN is taken orally, it has to cast the phosphate to enter the cell as NR. It then pickup a phosphate molecule intracellular, and converts bac to NMN, and then the nd product - NAD. And no, thee is not a dedicated kinase pathway for NMN to enter a cell intact.
The upside of a drug company testing a drug that might reverse Alzheimers and Freidreich’s Ataxia is they have the money to do high quality research, and if their research shows that the drug works, the number of people who take NMN will be many, many times greater than it is now.
@@WellnessMessiah thank you for that.
@@jeffgilligan2004 translation for the less literate please.
Thanks Rimon for your analysis. I was a big Sinclair fan until the sale of Resveratrol controversy erupted. I have become much more skeptical of his motives.
As a holistic doctor I’m disappointed at this point in time. I share your thoughts and feelings. My suspicion is that NMN may work as well as or close to as well as the new potential drug. So it appears to be a money thing for company and investors that could charge $$$$$ for the drug compared to $ that NMN cost. And do they really want to help the great number of people with NMN for $ ????? It’s not about safety to ban NMN. And if we are well with NMN the new drug would possibly not have the selling point they could get with the drug.
You're right. The whole thing doesn't make sense. I'm befuddled by the motives here.
If you dont want to used its your choise....But NMN is a very good product and I think that is good to use, and dont bay antybiotics or other drugs. Everything is money...to be in the good health of course is for rich people. But nobody work for fee...Normal...I use NMN and Im very good health. Im 75 years old. HMN from Zarapharm. Bye
Similar to basic Creatine which is very cheap, and the other expensive supplements that CONTAIN Craetine
It's sad when our heroes fail us.
Dallad don't give up yet! Sinclair may have been naive a bit and could have lost control. He could be the same person you think he was.... just a bit naiver than might have imagined.
Greed is a powerful thing.
He alresdy made money when we bought his book. Now he plans to make a lot more by using NMN as a drug.
@@melonymaiko9666 He's not Jewish, and u don't even know what a real Jew is, you antisemite
The US pharmaceutical industry is horrible and ruthless. How much of this is Sinclair vs pressure from his investors. Pharmaceutical research is very expensive. He might still be the good guy in all of this, but it may not matter. There does need to be a large public outcry in which politicians are getting pressure from their constituents and unfortunately competitor companies paying lobbyists to influence legislation.
Informative video thank you, it gives me hope. I just got tinnitus and hearing loss due to aging so I was hoping NMN could help.
Hi Turk Nice to meet you. I guess I'm too rooting for Sinclair to convince us that he lost control over his company and now he will try to make amends.
Sometimes tinnitus is caused by cranial nerves being compressed as they pass through the skull. This results from chronic nutritional deficiencies of minerals and bone-building nutrients. Typical MD's will not be able to help you. Treating the symptoms will never address the causitive factors of the problem.
@@michaelayalaathotmai
Could you please share what supplements help with bone- building nutrients?!
Thanks!!!
Note: Dr. Brad Standfield MD, (TH-cam) ask Sinclair to respond to a medical question and Sinclair blocked him. Who would do that?
I recently came across your Channel and love the work you do for this longevity Community. I've been following David Sinclair for a while, including Dr Brad Standfield. I've watch a few of your videos and like the deep information you give us, about David Sinclairs supplement stack and intake. I am worried about the NMN Ban and hope he comes out to speak on the Subject.... I just hope he isn't going against the Longevity Community!
Nice to meet you. I'm like you. I guess I'm rooting for Sinclair to convince us that he lost control over his company and now he will try to make amends.
My husband, 74 and I 67, have both taken NMN and before that NR. Because we also changed our diet to low carb with intermittent fasting and supplementation with various specific vitamins so I can't say specifically that the NAD precursors made a difference. We started with Dr. Gundry's products, then felt like we were getting snake oiled. I still believe that Gundry has his finger on the pulse of longevity research but he's trying and is making a fortune. We tend to think if a researcher makes money from his research he's a sell out. But wouldn't anyone want to profit from his life's work?
Thanks for your courageous speaking! I totally agree with you! I feel the pain of be abandoned from a beautiful mind. I hope not! I love Sinclair too a lot. ! My love to you and your people!
NNM an NR do the same thing. If NMN becomes hard to find, switch to NR. The problem with these molecules, is it is very hard for them to be absorbed in large enough quantities to be effective.
Nmn has greatly improved my energy. I have hypothyroidism and a neurological autoimmune disease. This is the only supplement that has ever helped improve the quality of my life including pharmaceutical medications or other supplements.
I have under active thyroid too ,could you please share which brand of NMN are you taking?!
Greatly appreciated 🙏
Well spoken as always!!! EVERYTHING YOU STATED IS TRUE!
All the best to you and your wife!!!🙏💙
Thank you for seeing me Monica.
I'm taking here personal risks myself to support our community. To put me forth like this.
Some people don't realize I've made this video for you, for our community.
We have 4 historical examples (of section 201) of what happens in those situations.
This is the time to put public pressure on his company. The FDA won't follow through if his company won't go further.
This is the time to put pressure on them. This is why I've made this video.
@@WellnessMessiah
Hi Rimon, could you please share the best doctor or treatment for your lovely wife ,my youngest brother has similar issues and I am looking for a good specialist, it's really hard to find one ?! Greatly appreciated 🙏🙏🙏🙏😍👍❤
I’ve been on the NMN train forever but lost confidence in Sinclair when I started to do more research from years ago around him being a cheerleader for resveratrol and then him dying his hair, getting Botox injections and using a beautification filter whenever he’s doing videos.
I also think Sinclair is sharing stories and not scientific facts.
Sinclair’s silence speaks volumes.
All that his silence does is allow everyone to fill in the void with their own conclusions.
Not true. He knows very well about the turmoil it’s causing. If it was done in line with his objective to make things better for everyone, responsible and honest reaction would be to step out and explain that in the light of new development. Why wouldn’t he in that case? If his objective is self-profit - then the most sensible thing is, of course, to keep silence, at least that will - may be - keep ppl guessing.
@@Always-xl9db your response agreed with me. But maybe you just wanted to be right.
Does it? What's it saying then? I thought silence gave you no information and if there was any hypothesis gained for my silence it would have a narrative or bias
It wouldn’t if David wasn’t such an outspoken, public figure with his social media, podcasts, IG feeds where he clearly projects himself as a scientist whose goal is to make the world a better place, cure disease of age, reduce epigenetic test cost for ppl, he makes a point that he is not for-profit and doesn’t affiliate himself with any NMN brands and so on….so yes, in the light of these statements, his current silence is inconsistent and is, in fact, an action in itself.
Even asking for “protection against competition” in a free market is a D move, but in the case of a longevity substance…even more so. David Sinclair has revealed himself as an almost cartoonish corporate villain, like the dude in Total Recall who monopolized oxygen on Mars and then charged people to breathe.
Yes Anothony, if the new product is so good, NMN wouldn't stand a chance anyway. So why to ban it?
Totally agree with your assessment on the general state of supplements after the NMN band attempt by Sinclair's cofounded company. I use to listen to Sinclair for a long time. Now I believe he is just another $ hungry entity like any other drug producers. I am done with him and discard his lame letter trying to distance himself from the company that is promoting the band NMN.
You have my full respect. I am sooo glad I run into your channel.
Adding to the absurdity is that David Sinclair has said in past interviews that he doesn't have a prescription for Metformin, but rather sources it from countries that don't require one.
Then we must do what he does. It's already easy to get metformin from other countries. I think it might be easy to get NMN overseas as well.
I appreciate this video and you wanting to be fair. I am far more skeptical of Sinclair's motives given his involvement in the Resveratrol GlaxoSmithKline fiasco. If he walks like a duck, and quacks like a duck, he is certainly not an eagle!
Nice to meet you here David. I hope to host him here in this channel and let him explain his positions nevertheless.
@@WellnessMessiah I promise to be nice and respectful.
In my country, Estonia, selling NMN has been banned long ago. It is explained away as novel dietary ingredient with unknown effects, with unkown safety.
Update: the FDA has requested that companies stop production of NMN supplements as of Dec. 7, 2022. Companies still can continue selling, but the FDA can stop NMN sales anytime now.
Money... the answer to 99 of 100 questions.
Best lesson learned is to never substitute facts and reality with cult-like beliefs surrounding a single person. Especially when the person has a prior history of similar money-first ambitions with the science he promotes.
Thanks for the video!
I just wonder, now I can get Tylenol or Aspirin in Amazon and my local pharmacy. Could it be that in the future, NMN may be available without prescription in my local drug store, not in my health food store.
Hi Emilio, I'm no optimistic about that. Most of these drugs used to have patent , established as a drugs for 2-3 decades, and only then when it's expired you had this status. It's a long way for NMN to go.
The FDA and David Sinclair should be ashamed. There is a higher judge we will all meet and be judged by one day. How dare they try to take away a nutritional supplement that so many people need. I would protest this ban.
Just my 2 cents on NMN, I'm in my twenties for reference so maybe I'm young for someone taking this. I personally feel like its one of the few supplements I've taken that I've noticed a real tangible difference before/after. I take 250mg liposomal non once a day most days. When taking it I feel a general feeling of well-being and energy like I had a really good night sleep. Perhaps its a placebo effect? Hard to say to be honest. But I feel Its been good more me after taking it for 2-3 weeks
Yes makes sense Rex, as it takes time to accumulate. Thanks for telling us your results.
Just take NR (Nicotinamide Riboside). It does the same thing as NMN, which it converts to after entering cell. It isn't and won't be banned.
A tweet came from Dr C. Branson saying may be NR may cause cancer & some others there to discuss,have a look at the tweets if you like😞
I saw on 11 Now after
Midnight.it's scary. Xxx
@@semaaral2498 This was quickly debunked.
Thank you for sharing your thoughts. I follow David Sinclair, as well. I hope that he will come out and speak to us. We need answers. 😢
Agree 100% with you ad all your arguments. I would be very very SAD if the excellent Saint Clair turns out to be just another BAD. I hope that such is to the case. Please come out Saintclair ad speak out.
Nice to meet you here Philippe. I hope to host him here in this channel and let him explain his position.
I wonder how difficult would be import NMN to Mexico from the same lab that Donotage gets its NMN. In Mexico is so easy for companies to obtain their licence. However nobody knows NMN. But people love their supplements and more in my city. We even have our own Herbalife Mexican version. Any enterprise in Mexico though sounds very dangerous.... However there are a lo of wormholes. An example, our Social healthcare system is stuffing our people with metformin, may be because we are fat.
Nice to meet you here Cynthia. Well I l consider myself Mexican now since I love my supplement too :)
I am so glad that you put out the information about supporting you I’m going to join that and support you and my best to your wife in every way you’re a good man I really admire that you’ll be hearing from me soon
My ailments are chronic, and so get better and worse and better and worse. I can never tell with any degree of confidence whether a supplement is heping or hurting.
What is wrong with you? My husband has got ataxia, and it doesn't help but it doesn't harm it is just the same. What I do know it that when he was young he could walk with no problem.
@@cynthiacovarrubias7096 Sorry about your husband’s difficulties. I still take a whole bunch of supplements in the hopes that some will be helpful even though it’s hard to tell when a supplement is helpful.
@@cynthiacovarrubias7096 atrial fibrillation
@@gabymalembe Eat magnesium and potassium and fiber- heavy food. These minerals balance out calcium that may over-signal heart muscle - also incorporate more calcium-channel blockers in food - ginseng, turmeric, olive leaf estract are Ca+ channel blockers, just to name a few, there is tons, usually in plant food. Avoid meat-heavy food and refined.
Hawthorn extract act more through other mineral channels but also beneficial. More indirect effects would be through beta-adrenergic receptor blockers (beta-blockers for short) - hawthorn has indirect effect there as well, as well as magnesium and curcumin that lower stress hormones that act on beta-receptors.
In recent times, spike proteins from biological weapons destroy gut bacteria - ths in turn has effect on vascular health. So keep the gut healthy - eat fiber (not huge amounts when not used to yet), fermented food (not huge amounts when not used to yet), turmeric and resveratrol, omega-3, absinthum species plants, oregano, many other spices control the pathogens in the gut (you might not feel them grow but the effect is through immune and inflammatory processes in the body) - gorwing healthy gut flora takes time and all of the treatments (curcumin, NMN, resveratrol, phytoestrogens in soy, flax seed) act through bacteria first metabolizing the components - so the changes take time for months or few years - don't expect quick changes -
common mistake people make is that they expect quick changes to chronic conditions, BUT the conditions are coupled to very long acting microbial changes.
Keep fighting the good fight! Hope your wife continues to improve 🖖🏼
Thank you for seeing me.
I'm taking here personal risks myself to support our community. To put me forth like this.
Some people don't realize I've made this video for you, for our community.
We have 4 historical examples (of section 201) of what happens in those situations.
This is the time to put public pressure on his company. The FDA won't follow through if his company won't go further.
The only unknown here is what role or control Sinclair himself has in this situation.
And I clearly stated, repeatedly, that we don't know.
@@WellnessMessiah I hope you are successful & we can continue to use this ‘vitamin supplement’. I’m in Australia & hope our equivalent regulatory body doesn’t follow the FDA.
The new drug formula has not been announced yet and I am wondering if the NMN ban is because maybe the drug is a formula of NMN and another substance that increases NMN, like Apigenin or something similar that hackers can sell the NMN and the additional substance separately. If the new drug is a more crystalized form of NMN then the company has nothing to worry about.
It is time to start a petition to stop the over reach of the FDA trying to require a prescription for NMN. 35 years ago we petitioned to stop the FDA from taking control of vitamins and supplements and of course making them more expensive. Requiring doctors to prescribe NMN is not really a viable option as doctors are only required to take 1 class in nutrition and information online is more up to date than the doctors! Please petition!
Sinclair knew what he was creating and aggressively created a demand to remove it from the market to control supply. He did it years ago when his company released, removed, re-entered resveratrol then sold it for $720M. It's all about the money. There's no ethic attached to his work. Pisses me off.
Correct me if I'm wrong, but a banned supplement is different from a "controlled substance" drug right?
Like is would still be possible to bulk purchase nmn powder marked for science use I'm pretty sure.
Hi Adam, good question. NMN is so expensive so buying it in KG would cost thousands for every individual.
Dr. David Sinclair has a conflict of interests. He is connected to that company. Pharmaceutical companies want to maximize PROFITS above all else. Dr. Sinclair's highest priority is maximizing his profits and career FIRST. I do think he cares about human health, but that's secondary to his career and profits.
I agree with evrything you are saying I follow Dr Sinclair a lot ❤
Nice to meet you here Angela.
I say he has been forced, i have been taking nmn for 2 weeks and i am blown away how much energy i have, my eye sight is better and i think more clearly. I am 55 years age....🙏
Being 1000 times more potent is not in itself a large benefit. The proper metric is a cost-benefit curve.
Unless their new drug pushes that cost benefit curve out in some way, whether reaching benefits impossible for NMN to reach, or reaching the same benefit more *economically*, the increasing potency doesn't matter. We're currently talking about a gram of NMN as the scale of a dose. 10 grams, a tenth of a gram, who cares? If the *optimal* dose is in that range, with the optimal dose for his drug simply scaled smaller because of potency, then I'll take the more economical of the two.
I agree with you. the issue is companies care about profit benefit, not cost benefit. the NMN is unpatented.
I love David Sinclair...my love is developing small cracks...
1st of all, on reading Sinclair's book where he seems to say "all of these longevity discoveries are for you, the general public" a suspicious bell went off in my head. These discoveries are for the people who can pay, & they are for the financial benefit of those working on the discoveries. In other words, longevity through chemistry is for the wealthy. That's a no brainer. But the disgusting aspect of all this, is to take a substance, like NMN, which was not invented by Sinclair, et al, and which is already being used by the public, and designate it for exclusive use by a company who intends to make big bucks off of it is pure corruption. But that's the unwritten role of the FDA, protect drug company profits.
This is nothing new for Sinclair. A few years he popularized resveratrol as a potent anti-aging substance. He then started a company that allegedly had a far more potent form of resveratrol, but it was a drug. The company was then sold for $720 million, but the drug turned out to be an abject failure and was never released. Sinclair is a scientist, but he is also an opportunist, and I question his motives. No legitimate scientist who studies aging would suggest that it was a disease that has a cure, as Sinclair does all the time. A lot of people put him on a pedestal because of his frequent outlandish statements, but those who are rational and have a knowledge of how true science works know better.
I use NR instead of nmn.I take most or all of his protocol.honestly never feel any different. But worth it if it works.
The real problem here is the USA Congress who passed a law protecting companies over individual rights. Talk to your members of Congess.
I wish my husband could have taken nmn after his stroke. Why don't doctors perscribe this? Neither the VA or outside health system mentioned this supplement to us, I am very sad.
Great video. Thank you.
Sinclair is decent, honest and very naive. He had no choice but to fall in the trap of criminals, hungry for money
Jorge A. Carpio, MS, PE
Nonsense, he knows exactly what he's doing. Why hasn't he responded to all the criticisms? If there is anyone who "naive," it's you.
It could very well be Jorge. He could be naive, That's my feeling too.
My goal in this video is for his company team to watch as well.
We have 4 historical examples (of section 201) of what happens in those situations. This is the time to put public pressure on his company. The FDA won't follow through if his company won't go further.
The only unknown here is what role or control Sinclair himself has in this situation. And I clearly stated, repeatedly, that we don't know.
I'm taking here personal risks myself to support our community. To put myself forth like this.
Not surprised if we find out that NMN doesn’t help… When money is involved, be aware. Supplementation on basic minerals missing in our food is your best bet!!!! Only thing I have seen a noticeable difference on my energy level .
It makes sense from a business perspective. You just have to ignore ethics.
Yes, this makes no sense at all. And it makes me VERY angry. I don't want to go on a rant but this offends me in so many levels. Denying people autonomy over their bodies is evil especially when it affects their health.
I've taken NMN, which I first heard about from Sinclair, for about two- three years now. It has made a HUGE difference in my well being and the prospect of losing access to it is awful.
And for you it is even worse because of your wife. You should have access to all treatments to help her!
But that's where I stand right now. This sucks and I'm angry.
On a brighter note, I've recently found a good supplement that I think will activate SIRT6! I'm very excited about it!
Hi Jason glad you've found it. My goal in this video is also to put pressure on Sinclair's company. I suspect he lost control a bit. If they won't follow through, the FDA won't ban it.
Is there something the people can do to stop the banning???
I wrote my representative just a day ago. I haven't heard back yet but I believe she will do what she can as she is not one of the power hungry , money grubbing pigs. She is a true patriot and a person of the people.
yes Eh Eh, I'm doing my part here.
We have 4 historical examples (of section 201) of what happens in those situations. This is the time to put public pressure on his company. The FDA won't follow through if his company won't go further.
In addition, the FDA doesn't decide everything and it can go to upper courts.
Not yet, the iron is hot. My goal is for his team to watch this video too. And him.
I'm taking here personal risks myself to support our community.
What NMN brand is authentic and honest company
I keep on sending my prayers to your beautiful wife.
You are a unique person & sure
God will award you🙏🌹🙏🧿🧿🌹
Thanks for sharing your Resveratrol dose, I dropped it after your one of the podcasts.
Today gave me the chance to confirm it after sharing your dose.
Every other day 200mg around,
I take.
I don't have a smaller spoon than this😉🙏⭐💛🎄💛🦌✨
We’ve loved our Valuable Scientist but maybe he didn't care about us that much😞
But he'll respond to you, I'm sure.
Also, I laughed at a commend,
under one of his latest podcasts,
A follower Saying, " please let “Regular “people keep on buying NMN,
don't ban them😂😂😂
God Bless you & your wife🙏🙏🧿🧿
Thank you Sema. Reducing resveratrol also save some money too haha:)
Dear Rimon, Thanks for reading my comment .
Nice to see you full of hope again🙏⭐💫✨
I hope All goes well 🙏
Hope your & our Valuable Scientist give more advice about your beautiful Wife's situation to you🙏😞
He must be busy or maybe his character is different🤔like my son's.
What I meant is;
This type of different soul is determined to do things in their own time, you can't push their cause,
Once they've been broken in the past😌
they have their own rules, ego's now.
I live 5 min away from my son but sometimes he calls me back
after I got well😅😅😅
They are too busy with their business life and their phycology🤯is always up & down😞😞😞
Looking forward to hearing about your next video.
Whatever you share it's valuable to me.
God Bless you & your Wife🙏🙏🧿🧿
Them... Correction🙏
It is a shame, that Dr. forget his promise to serve humanity of man.
Do you recommend an special NMN brand that works?
If they do ban NMN, it sort of feels like the government breaching human rights.
this community CANT be too large. Too many plebs does the rich no good in their fantasy of a de-populated earth full of beautiful, immortals
To give a product that is so helpful to so many people and actually promote it … and…. Then take it away is worse than cruel. Who’s influencing you David Sinclair?
Hey Rimon :)
Regarding your wife and stroke - have you looked into the potential benefits of methylene blue for post stroke? Its impressive. Many other benefits that are pretty mindblowing too.
Wishing you and your loved ones the best my good man ❤
Is it possible that Dr. Sinclair is deferring to the government or, and affect deflecting so as to avoid blame or responsibility and still maintain profitability for himself and his investors? On another note I sent prayers and hopes out for your wife’s health as well as yourself and I appreciate you posting this video it is very interesting and a little heartbreaking that so many people will be adversely affected by what in my estimation is the creation of a monster
You guys really didn't see through his charade? It was pretty obvious from the beginning that he is involved in some high stake games.
It is shitty what they are trying to do. But i am not surprised in the least.
It's just so bad. I understand someone wanting fame and fortune. But why should people want more than 200k a year on tenure? I mean, if you're somewhat cautious with spending you can retire at 55.. And then just ask money for interviews or for endorsements and maybe speed up the earning process. I do understand that people want even more than that. But never enough when it doesn't benefit the greater good? That's just rubbish.
I pray that you will succeed
Thank you for seeing me Steven.
I'm taking here personal risks myself to support our community. To put me forth like this.
Some people don't realize I've made this video for you, for our community.
We have 4 historical examples (of section 201) of what happens in those situations.
This is the time to put public pressure on his company. The FDA won't follow through if his company won't go further.
The iron is how now.
The only unknown here is what role or control Sinclair himself has in this situation.
And I clearly stated, repeatedly, that we don't know.
money and greed are at play with Dr Sinclair position with NMN sad as it may seem.
Sounds to me like Dr. Sinclair is too worried about money he is about the people taking what he develops for a reason shame on him
I think that Sinclair has been suffering from brain fog since he went vegan: not surprisingly. Gone over to the Dark Side.
I've always been intrigued how DS is a scientist but has no science to back up his vegetarian bias
Hi Christopher, Sinclair may have been naive a bit, in addition to dietary changes (joking)
@@WellnessMessiah
We are what we eat.
Me: 200 days without carbs of any kind, excepting coffee.
@@timh-c7186 harvard. Their diet section is dominated by seventh day Adventist whose mission us to convert us all to veganism.
I noticed also, that he was not looking as healthy as he did prior to the vegan food switch. I hope he goes back to a more balanced diet so he can regain his healthy glow again.
Real innovation is not for YOU or me. Its for the elite. Michael Jackson was doing hyperbaric chambers in the early 80´s when we were hearing about it 20-30 years later (he was hardly elite, but rich with connections). Our access to Chat GTP is the low-end tech. Its much more advanced- but not for US.
Did Sinclair's company head off a reported IPO for a longevity capsule in February 2023, where Bezos of Amazon, Thiel of PayPal and Rockefellers have reportedly invested $US100 million? Note, this occurred after Amazon banned NMN in January 2023. Sinclair, as a researcher rather than an investor, may have vacated the conversation to enable his company to address this possible competitor.
Daivid Sinclairs business is developing new medicins. As I understand what he said is that he has asked FDA to regulate NMN. That is not the same as banning it. Now the FDA may have rules in regards to this request and that may be to stop selling NMN over the counter until it can be regulated or be denied regulation. Anyways there are at least one company out there who sells NMN as a chemical and not as a supplement. A ban should only apply to supplements so even the Americans should be able to get around this if it happens.
Boils down to da MONEY ! Just like STATINS their cost to the cost of niacin which does basically the same but one is prescription the other over the counter , and many other drugs that are prescribed but can find alternative over the counter , If Sinclair has found a more effective product than that of nmn then the obvious thing to do is like any other competitive product either purchase the rights or find a way to prevent the consumer from using it and then PROMOTE your product at YOUR price ! So if investment in new product and new product better than the previous one and want a return on the better product and your the sponsor of the previous one , and still save face ! Then have the FDA BAN it for you ! Not your fault ! But hey got something better for my loyal consumer ! But the FDA Has to Approve It First and then NOT my FAULT but it going to be by prescription only ! and at HIGHER PRICE ! Not my Fault ! I love people ( money ) ! Investments and investors are there for PROFITS, Squeeze and SQUEEZE ! Then once the FDA bans nmn then those who had faith in humanity will be at the mercy of a prescribed product that would have to be given from a person that would make the decision if you are WORTHY of using this product and at the same time the person that prescribed you the product is looking younger all the time ! Or the FDA may ban the old product and the new product for the consumer and. Allow it's use for research only ! Just like the substance Trodusquemine discovered in cancer research and found with one treatment in mice it CLEARED ALL CHLOSTEROL PLAQUE in their little mouse body ! Now since Heart Disease is a Main killer How would Trodusquemine have an impact on saving human life ? BUT by the FDA it is BANNED for consumer but ALLOWED for RESEARCH ONLY ! WHAT ? WOW ! GOOGLE IT !
If David is going to live to 200 he’s gonna need a lot of money…there’s your answer
I am sorry that money stps the Freedom to speak common sense
I’m very disappointed in Mr. Sinclair! I really thought he was a good guy.
I think Dr. Sinclair is spending too much time with Elon Musk.
Lawsuits
Attention all listeners, reply to me to work with me to find a way to make nmn ourselves! Then they can't stop us
I guarantee it’s his funding
Sinclair only cares about money. No doubt NMN improves health but Sinclair dyes his hair, wears make up and has a state of the art lighting, camera and filters. I never trusted him and now he shows his true colours.
Im sure his Dad is still getting his NMN. Fuck the rest of us.
please stop blaming the man for working, he has bosses that funded his research and probably by contract must do as bid anymore than I blame the newscaster for spewing garbage elected for that days broadcast by his bosses, he gave his views on everyone living longer so I am fine with that, am glad he did the work, got the message out in time so we can take the blame were it belongs, the elitists, the rich and government that would use such an affordable supplement for jacking up the price and "reducing the surplus population", the last of their choice of course
are we jumping the gun here? we haven't heard from Dr. Sinclair's side of the story. and another thing is Dr. Sinclair's job is to find a way to cure aging, he doesn't have to explain his action to anyone. you'll never get anywhere if you have to explain everything to anyone who questions your action.
Great question unbox.
It's not jumping the gun at all.
Sinclair's company (which he confounded, hence "his") filed a request to activate the preclusion provision of section 201. Meaning, a request to stop the sale. It already happened.
And the FDA already sent a warning letter to abide.
We have 4 historical examples (of section 201) of what happens in those situations. This is the time to put public pressure on his company. The FDA won't follow through if his company won't go further. The only unknown here is what role or control Sinclair himself has in this situation. And I clearly stated, repeatedly, that we don't know.
Some people don't realize I've made this video for you, for our community. And for his company's team to watch.
I'm taking here personal risks myself to support our community. To be put forth like this.
Huh. What ?? Am I missing something ?? Aging is described as a disease. Since when did this happen ? Did I miss something ??
Dr Sinclair?
Sinclair is behaving like a weasel!! Shame
Standard American
All Sinclair is trying to do is to clean up the supplement market with all its bad NMN products. When that’s done, he will come back with a safe and working NMN product. I think that’s awesome.
lol. its all about the money. aimple
Its not banned!!!!!!!!!!
High dose niacin is a better replacement. 3g daily. Target that.
AMERICAN AND AUSTRALIAN GREED.
Please don’t “experiment” on your wife😅
Do you have a go fund me? I would be very happy to make a sizable contribution to the health of your wife
clicK bait no such thing as stated extsts. Author of video says so in first sew seconds. Sinclair appeared a day later and was not concerned at all. did not hear of it (Because it did not happen).
David Sinclair is committed to longgivity but don't forget David is a fine Jewish Businessman, who by design is trained to prioritise profits above everything else.
Ouch
Niacin is part of nmn if they outlaw nmn there's always niacin
Sinclair has always been about the money - how many millions did he make off of his resveratrol investment before the company abandoned production? en.wikipedia.org/wiki/Sirtris_Pharmaceuticals