Pharmacokinetics | Drug Metabolism

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  • เผยแพร่เมื่อ 7 ม.ค. 2025

ความคิดเห็น • 173

  • @wanahmadamsyarzafrie8080
    @wanahmadamsyarzafrie8080 2 ปีที่แล้ว +247

    Man I love the new quiz-types questions at the end of the video, they really test your memory, the videos/notes and illustrations are super great as well, thanks Ninja Nerds

    • @NinjaNerdOfficial
      @NinjaNerdOfficial  2 ปีที่แล้ว +40

      Glad you like them!

    • @naderahmed7938
      @naderahmed7938 11 หลายเดือนก่อน +7

      Please keep adding more quiz questions they really help solidify the lecture also thank you @@NinjaNerdOfficial

  • @onesmuskennedy3400
    @onesmuskennedy3400 ปีที่แล้ว +35

    Should pay my tuition fee here

  • @marquisdesade6156
    @marquisdesade6156 2 ปีที่แล้ว +85

    The thing that I absolutely love most about your phenomenal teaching is THE REPITITION, it does incomparable WONDERS for students MEMORY and so many teachers just pass through a term once and stroll on,, making it easy to forget

  • @automntl
    @automntl 2 ปีที่แล้ว +125

    The fact that these got uploaded just in time for my pharm course is excellent. Im not religious, but I know Jesus loves you. I met him shortly after watching this.

    • @Ronaldo71543
      @Ronaldo71543 8 หลายเดือนก่อน +3

      Wtf 😒😅

    • @FadumaAbdullahi-o4m
      @FadumaAbdullahi-o4m 3 หลายเดือนก่อน

      R u serious? 🙄

    • @automntl
      @automntl 3 หลายเดือนก่อน

      @@FadumaAbdullahi-o4m wallahi

    • @alimenhem3348
      @alimenhem3348 หลายเดือนก่อน

      Sure... its getting overused now

  • @khalilahd.
    @khalilahd. 2 ปีที่แล้ว +36

    I don’t know how you do it but you make complex processes so much easier to understand! Definitely saving this for my watch list! 🙏🏽💜

  • @gotenks81
    @gotenks81 4 หลายเดือนก่อน +4

    I've unfortunately pursued a career path completely different from Medicine and now, at 43 yo, I feel an insane frustration, every single day, because I'm not happy at all with my job. I love so much Medicine, Pharmacology, Biology that every time I get into this topic people around me always say that my eyes start sparkling. In my spare time I'm studying on my own since that's the only way I can find a tiny bit of happiness. Your videos are such a refreshening, delightful caresses for my mind that I'm devouring them one by one. Thanks for this great work!

  • @AbuhurairaJamil
    @AbuhurairaJamil ปีที่แล้ว +8

    Never have I ever listened to pharmacology lecture for 40 minutes straight until now😂. Hats off man ❤

  • @איתיעובדיה-ו4ל
    @איתיעובדיה-ו4ל ปีที่แล้ว +5

    By far, you are my best prof. in med school!

  • @iyayii
    @iyayii ปีที่แล้ว +6

    I have my pharm midterm exam in four hours and was confused on the topic. My notes and lecture slides didn’t help. Your video really helped break it down and make me understand the topic more. Will start watching your vids from now on!

  • @lydiakaoudjt9369
    @lydiakaoudjt9369 2 ปีที่แล้ว +34

    Thank you is never enough for your efforts dr ninja nerd. May Allah bless u and all your beloved ones u are making our life easier thanks a lot

    • @shaikabdulrafey4981
      @shaikabdulrafey4981 5 หลายเดือนก่อน +1

      Bless with the greatest blessing Aameen

  • @MichaelBrown-sf6py
    @MichaelBrown-sf6py 2 ปีที่แล้ว +6

    Mr professor taught this today and had me completely lost and I didn't think I would ever understand this. But the way you break it down makes sooooooooo much sense so thank you.

  • @riogrl324
    @riogrl324 ปีที่แล้ว +4

    These videos have opened my eyes! FINALLY someone explaining it without confusing the masses 😂

  • @jaygala9420
    @jaygala9420 21 วันที่ผ่านมา

    I never got general pharmacology right until I watched your videos. My 2nd year final exams are going on and your videos are saving me and helping me to write something in exams! Thank youu Ninja Nerd Team and special thanks to you Dr. Zach.

  • @marianamelo9672
    @marianamelo9672 2 ปีที่แล้ว +14

    these classes are GOLD! your teaching makes us excited about learning, thank you!

  • @ssburrus
    @ssburrus ปีที่แล้ว +2

    grateful you are single-handedly teaching me my first few weeks of PA school :')

  • @rashmijagadeesh5753
    @rashmijagadeesh5753 11 หลายเดือนก่อน +2

    You made such a complicated topic into simpler job that I never forget the concepts which you taught . I admire your efforts and thank you so much 👍

  • @muhammadusama1347
    @muhammadusama1347 2 ปีที่แล้ว +10

    Am addicted to Ninja

  • @camillepage208
    @camillepage208 ปีที่แล้ว +1

    Omg THANK YOU THANK YOU THANK YOU!!! I am studying to be a therapist & am struggling with my psychopharmacology class. You have helped me understand way way better than the book could. Thank you so much for breaking this down so it’s understandable to people who have 0 foundational knowledge like me!

  • @calvinklein6903
    @calvinklein6903 2 ปีที่แล้ว +5

    This dude right here is the GOAT!

  • @AliRahat-u2w
    @AliRahat-u2w หลายเดือนก่อน

    You are just a life saver for medical student, who find these concepts complex to understand. You are just amazing to memorize this huge sum of knowledge and delivering it with such smooth flow. May God bless you❤

  • @anulikaizuchukwu7198
    @anulikaizuchukwu7198 ปีที่แล้ว +2

    I have struggled for so long to understand this phase 1 and 2 reaction. This video made it so easy. Thanks alot!

  • @tinkerfae1977
    @tinkerfae1977 11 หลายเดือนก่อน +1

    Zachary your amazing I have turned my uni colleagues onto your channel and they are all so grateful , I have even been given all clear to use your website in my references xx ❤

  • @anouckvanes
    @anouckvanes ปีที่แล้ว +1

    You are really the best teacher I never had! Please keep up the good work

  • @taliarabelo4034
    @taliarabelo4034 ปีที่แล้ว +2

    Hello! This class helped me a lot, I'm Brazilian and I was having a lot of difficulty understanding this subject, but with your incredible didactics it's impossible not to learn. Thank you very much!

  • @brazuca14
    @brazuca14 ปีที่แล้ว +2

    I’m Acing CRNA school thanks to you!!! Thank youuuuuuuu.

  • @ngumkapapi7222
    @ngumkapapi7222 4 หลายเดือนก่อน +1

    Ninja Nerds a godsend to the medical profession

  • @mamalyfarahmand592
    @mamalyfarahmand592 ปีที่แล้ว +1

    thanks to you and the team that is supporting you

  • @peaceomada9488
    @peaceomada9488 2 ปีที่แล้ว +2

    I like the fact that you try to make everything simple and make everyone follow up

  • @coconut2262
    @coconut2262 2 ปีที่แล้ว +6

    I was actually terrorised in med school when my teacher taught us this..couldn’t understand a bit and when asked about 1st pass metabolism in my test it moved me to tears to write what I had in my mind..
    Thank you so much for this..🙏

  • @nnajilight8008
    @nnajilight8008 ปีที่แล้ว +1

    Ninja nerd you don't know how popular you are among Nigerian university students...bless you brother

  • @22.Satty.
    @22.Satty. 2 ปีที่แล้ว +2

    Sir you are my favorite teacher for rest of my life thanks a lot 🙏

  • @ashu9178
    @ashu9178 หลายเดือนก่อน +1

    Jazakallah khairan kasiran kasira 💝✨️

  • @saffaayub4570
    @saffaayub4570 2 ปีที่แล้ว +1

    Grateful that I found them right before exam!!

  • @juanmartinvillamea378
    @juanmartinvillamea378 8 หลายเดือนก่อน +1

    the explanation is on point, as always

  • @fearlessgamershubandroidga9305
    @fearlessgamershubandroidga9305 11 หลายเดือนก่อน +1

    Hats off man.
    You're the best

  • @darlingrunnerpt3342
    @darlingrunnerpt3342 ปีที่แล้ว +2

    This makes sense as to why I have so many side effects with medications. Must be a very slow metabolizer. Had horrible side effects on 3 different DOACs. Hematologist had no idea why.

  • @Jay-lq8ly
    @Jay-lq8ly ปีที่แล้ว +1

    Best explanations!! You simplify all topics❤

  • @CloudBluesky-g7r
    @CloudBluesky-g7r ปีที่แล้ว +3

    Thank You ❤

  • @manalemad1589
    @manalemad1589 2 ปีที่แล้ว +3

    clear and informative that's what a med student needs
    endless thanks for the ninja nerd staff we do appreciate your hard work ❣❣❣❣

  • @mhammedsuiman6493
    @mhammedsuiman6493 2 ปีที่แล้ว +3

    Thank you so much 💓 💗
    I have an exam in pharma next week ..... i can't answer the cases questions but you help me...... thank you again ❤
    Great explanation 👌

  • @ummkulthumabdussalam6726
    @ummkulthumabdussalam6726 ปีที่แล้ว +6

    Hi, Omeprazole is an inducer not an inhibitor, thanks for the amazing class ❤️

  • @Jaycar1997
    @Jaycar1997 2 ปีที่แล้ว +2

    @ninjanerd First off I wanted to say that I love your videos. They've been keeping me afloat through med school.
    I usually don't comment at all but at 11:50 in the video you talk about codeine in slow metabolizers and in those cases I think it would actually be more beneficial for the children with low metabolism because codeine is a prodrug with the active metabolite causing respiratory depression. So it would actually be ultrametabolizers who are at risk for respiratory depression since they're turnover rate into the active metabolite is increased.

  • @sharminbala
    @sharminbala ปีที่แล้ว +1

    Very nice! Clearing concepts

  • @dominicbarandica6717
    @dominicbarandica6717 ปีที่แล้ว +1

    Add more questions going forward that was super helpful for a check of understanding. Keep up the great work. 😊

  • @minutemovienight9094
    @minutemovienight9094 6 หลายเดือนก่อน +1

    Thankyou so much Ninja Nerd! Your are doing great work. I will repay you one day

  • @Taemna7
    @Taemna7 ปีที่แล้ว +1

    I have no word to cheer up this angle😇😇😇😇😇

  • @JJadx
    @JJadx 2 ปีที่แล้ว +3

    apparently some people think doctors shouldn't google stuff.
    i'm so glad my doctor does haha. ain't no human remembering every drug interaction. great bg asmr for drawing once again b.t.w. mr ninjaman.

  • @doc_matox
    @doc_matox ปีที่แล้ว +1

    Just though of commenting on the wonderful videos i have watched recently. Thank you so much for making my Pharmacology journey going smooth❤❤

  • @samhasanpour1628
    @samhasanpour1628 ปีที่แล้ว +1

    Love love loved it! Much appreciated🎉

  • @karmagaming7112
    @karmagaming7112 ปีที่แล้ว +1

    Love u 3000 ❤️
    We are Ninja Nerds 🥷

  • @crespomwakapande6299
    @crespomwakapande6299 ปีที่แล้ว +1

    Thanks very much u make concepts easier

  • @AboobiadaAlmohager
    @AboobiadaAlmohager ปีที่แล้ว +1

    I love your science prof. Zach ❤❤

  • @coconut2262
    @coconut2262 2 ปีที่แล้ว +3

    😭😭😭😭😭😭 I can’t thank you enough sir..

  • @noahelia1579
    @noahelia1579 2 ปีที่แล้ว +2

    Allways a fan of these pharmacology videos! Such great content. I'd love to see one on pharmacogenetics and some in depth content on polymorphism of drug metabolizing enzymes.

  • @linaaa2535
    @linaaa2535 2 ปีที่แล้ว +2

    Please make more pharm videos! These are amazing, thank you so much!

  • @ShahMehrunnisa
    @ShahMehrunnisa 11 หลายเดือนก่อน +2

    Oh! how much I love this man and his expressions🤌🏻😉

  • @fatimah-2
    @fatimah-2 ปีที่แล้ว +1

    I followed you since 3y from iraq , keep going i respect you so much

    • @Ronaldo71543
      @Ronaldo71543 8 หลายเดือนก่อน

      May Allah heal the Iraqis whom suffered of cruel bush

    • @fatimah-2
      @fatimah-2 8 หลายเดือนก่อน

      @@Ronaldo71543 Amen

  • @sabaiqbal8873
    @sabaiqbal8873 2 ปีที่แล้ว +1

    Super great videos. I understand every bit of your lesson. Thanks are not enough for your efforts. Superhero, an ideal teacher.

  • @MatimbaHope
    @MatimbaHope 5 หลายเดือนก่อน

    Yhooo this guy is something else❤️‍🔥❤️‍🔥❤️‍🔥

  • @hamlilasma5434
    @hamlilasma5434 ปีที่แล้ว +1

    thank you infinitely

  • @alexmukisa
    @alexmukisa 2 ปีที่แล้ว +2

    I appreciate you so much doctor 👍

  • @sr689
    @sr689 ปีที่แล้ว +1

    Very well explained. Thanks

  • @eljubourii
    @eljubourii 2 ปีที่แล้ว +2

    Great explanation 👏🏻👏🏻👏🏻❤️

  • @doctortobe7345
    @doctortobe7345 ปีที่แล้ว +1

    Thnk u 🙌🙌🙌🙌 u're the best ever

  • @rebekahparris2425
    @rebekahparris2425 2 ปีที่แล้ว +2

    Thanks once again, you make learning so exciting and this isn't even necessary for my studies, just out of curiosity I wanted to know about this. I also love the Q&A at the end. ✌🏽🇹🇹

  • @PETEYBOY954
    @PETEYBOY954 ปีที่แล้ว +1

    This is so interesting.

  • @Lusungumsimuko5816
    @Lusungumsimuko5816 2 ปีที่แล้ว +1

    Thank you very much
    This very helpful and unforgettable 😊

  • @carolinaruiz6227
    @carolinaruiz6227 ปีที่แล้ว +1

    eternal gratefulness

  • @RobotChitti-j7g
    @RobotChitti-j7g หลายเดือนก่อน

    Thank you sir, may god bless you ❤❤

  • @tabatakalhelo3993
    @tabatakalhelo3993 ปีที่แล้ว +1

    Thank you doctor

  • @biybimaryamjoldasbaeva506
    @biybimaryamjoldasbaeva506 ปีที่แล้ว +1

    THANK YOU SO MUCH

  • @PeaceOffmate
    @PeaceOffmate 2 ปีที่แล้ว +1

    May Allah bless you and the entire team with immense success

  • @AMDALReviews
    @AMDALReviews ปีที่แล้ว +1

    Thank you so so so so much sir 🌷

  • @118_mirunaliniprem8
    @118_mirunaliniprem8 ปีที่แล้ว

    Nee nalla irupa ya manusha ❤ love from Tamil Nadu India ❤❤

  • @BaoTran-ls7oy
    @BaoTran-ls7oy 9 หลายเดือนก่อน +1

    Thank you for great explanation and visually appealing board content! In phase II biotransformation, there are additional two substrate which are Glycine and Ribonucleoside/nucleotide synthesis. Can someone clarify this? 😕. Thank you

  • @niyadeo7970
    @niyadeo7970 ปีที่แล้ว +1

    Amazing!!

  • @tahaalameri4832
    @tahaalameri4832 2 ปีที่แล้ว +5

    I think that the codiene become toxic when you metabolize it more, because codien metabolite is morphine, 11:50

  • @حذيفةأحمدسعيد-ح2ر
    @حذيفةأحمدسعيد-ح2ر 2 หลายเดือนก่อน

    Thank you, you are great.❤

  • @fatimaverse7892
    @fatimaverse7892 2 หลายเดือนก่อน +1

    Thank youuuu

  • @ChesnaT-u8t
    @ChesnaT-u8t 4 หลายเดือนก่อน

    Thank you so much 😢😢😢❤❤❤❤❤

  • @Shahzadraza333
    @Shahzadraza333 2 ปีที่แล้ว +3

    Good explanation 👍
    Just to notice, for CYP 450 inducers you mentioned the exls of CYP inhibitors and for cyp450 inhibitors the exls of CYP inducers are mentioned in haste. It is overlooked!

  • @mohammedabdulrehan6643
    @mohammedabdulrehan6643 2 ปีที่แล้ว +3

    Thanks a lot sir

  • @PerfusionPrime
    @PerfusionPrime 2 ปีที่แล้ว +1

    Thank you ninja nerd

  • @husseinsaied6061
    @husseinsaied6061 ปีที่แล้ว +1

    U R amazing ❤

  • @mirror9lifer
    @mirror9lifer ปีที่แล้ว +3

    I have a question regarding 18:48 - when turning a pro-drug into an active drug the effect is vice-versa. So an inhibitor such as Omeprazole would become an inducer, no? But then at 24:24 in case of a pro-drug activating we still have Omeprazole being an inhibitor.
    Not getting my hopes up that someone will see this comment and help out :)

  • @urmilakumari6328
    @urmilakumari6328 2 ปีที่แล้ว +1

    Amazing lacture!!
    Make lacture on pharmacodynamics plzzz

  • @Miah-jd1si
    @Miah-jd1si ปีที่แล้ว +1

    fantastic

  • @tilwedie23
    @tilwedie23 2 ปีที่แล้ว +2

    Do one on umbilical hernias or all the different type of hernias that can happen in the abdominal region. 👍

  • @shryf742
    @shryf742 6 หลายเดือนก่อน

    Thanks alot Professor Zac Murphy😊

  • @bobj9923
    @bobj9923 2 ปีที่แล้ว +2

    Dr zach, what's your specialty? Cause you make videos about everything medical and it's mind blowing!

    • @LoluOres-r3k
      @LoluOres-r3k 4 หลายเดือนก่อน

      Truth is, all this is regarded as basic knowledge in the medical sciences! Specialists go even further but in a narrower scope.

  • @bawanomer1244
    @bawanomer1244 ปีที่แล้ว +1

    Thanks.

  • @zainabfarooq5263
    @zainabfarooq5263 ปีที่แล้ว +1

    Thanks

  • @akinwonmioluwaseun6925
    @akinwonmioluwaseun6925 5 หลายเดือนก่อน +1

    I doff my cap Prof!!!

  • @prashanth-py9jc
    @prashanth-py9jc 2 ปีที่แล้ว +1

    Superbb sir always awesome

  • @rakeshshah1074
    @rakeshshah1074 2 ปีที่แล้ว +2

    U r amazing sir

  • @zizojaezekeom3565
    @zizojaezekeom3565 6 หลายเดือนก่อน +1

    Amazing video ❤ i have a question please : in case of activation of drug, it passes through the two phases too or it doesn't?

  • @himalaydebsourav
    @himalaydebsourav ปีที่แล้ว +1

    you are simple awesome!!

  • @саньокшевчук-щ1й
    @саньокшевчук-щ1й 2 ปีที่แล้ว +2

    Hi Bro, I am very thankful for your superunderstandable explanations and I may seem abrupt, but can you make a video about all fossa( infratemporal, temporal, pterygopalatine and so on). Please!

  • @lavinfatih8398
    @lavinfatih8398 2 ปีที่แล้ว +1

    Thank you

  • @joyasia2752
    @joyasia2752 5 หลายเดือนก่อน

    Good job