Pharmacokinetics | Drug Excretion

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  • เผยแพร่เมื่อ 4 ส.ค. 2024
  • Official Ninja Nerd Website: ninjanerd.org
    You can find the NOTES and ILLUSTRATIONS for this lecture on our website at:
    www.ninjanerd.org/lecture/pha...
    Ninja Nerds!
    In this lecture Professor Zach Murphy will be presenting on Pharmacokinetics, specifically discussing Drug Excretion. We hope you enjoy this lecture and be sure to support us below!
    Table of Contents:
    0:00 Lab
    0:07 Drug Excretion Introduction
    0:27 Mechanism of Drug Excretion
    2:19 Factors Affecting Excretion
    12:37 Reabsorption
    21:39 Comment, Like, SUBSCRIBE!
    Pharmacology Source:
    Whalen, Karen. Lippincott Illustrated Reviews: Pharmacology (Lippincott Illustrated Reviews Series). Wolters Kluwer Health.
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    / @ninjanerdofficial
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ความคิดเห็น • 125

  • @user-lm7fe3fy4k
    @user-lm7fe3fy4k หลายเดือนก่อน +5

    I can study from books, notes etc but none of them motivates me as much as your videos Zachary and the only reason for this is your pure passion for being a doctor. I hope that nobody dies before they discover their passion because there is nothing more joyful than doing the job that sets your soul on fire

  • @Kyle0714
    @Kyle0714 19 วันที่ผ่านมา +2

    best teacher ever Zach. I love how simply you can explain the acid base & alkalization of urine to excrete drug metabolites

  • @alsharabyalsharaby1483
    @alsharabyalsharaby1483 2 ปีที่แล้ว +28

    Before I watch your video , I know surly ,it's a great explaining , keep going please talking about pharmacology stuff, Thanks for your effort

  • @LA-ug6ol
    @LA-ug6ol 10 หลายเดือนก่อน +23

    visual learners cant be more lucky with nenja nerd !! Well explained ,Thank you so much for this great work ❤️

  • @mohammedisak4645
    @mohammedisak4645 2 ปีที่แล้ว +16

    Masha Allah I'm from Somalia🇸🇴 We proud of You Me and My friends For your Hardworking Thank you For Your Helping us With Out you I'm sure that i can't know something About Medicine.
    Thank you.

  • @fightersoul6436
    @fightersoul6436 ปีที่แล้ว +13

    Just beautifully explained ......hats off....the topic which I couldn't even start.. seeing the complexity of words ...this person not only explained it awesomely but explained it in a way that I will never forget the concept in life!❤️

  • @OmarFatimaZohra
    @OmarFatimaZohra ปีที่แล้ว +10

    Best explained videos ever ! I'm amazed by how much you can simplify the concepts honestly thank you so much

  • @yogireddy7209
    @yogireddy7209 ปีที่แล้ว +11

    You have cleared all of my confusions about this drug excretions thank you so much 😊🎉

  • @Farxiya-fc1jf
    @Farxiya-fc1jf 28 วันที่ผ่านมา

    You saved my grades so many times that I can't thank you enough ❤

  • @Fifa_sajad
    @Fifa_sajad หลายเดือนก่อน

    I have never seen such simplicity . Thanks for everything ❤

  • @22.Satty.
    @22.Satty. ปีที่แล้ว +5

    You make learning joyful sir it's the best thing about your teaching I am forever grateful 🙏

  • @cristianxavier5954
    @cristianxavier5954 ปีที่แล้ว +2

    just started taking Pharmacology classes and you have just saved me!!

  • @remembermabasa2247
    @remembermabasa2247 2 ปีที่แล้ว +1

    Thank you very much for this content.. I'm really enjoying and learning alot from these videos. Best teacher, everything make sense now.. Thank you prof

  • @rtsetse5826
    @rtsetse5826 ปีที่แล้ว +1

    Thank you so much for clarifying this topic!

  • @tanyagupta1509
    @tanyagupta1509 ปีที่แล้ว +1

    Tysm ninja nerd for explaining the concept it's great😃👍. Kindly keep going with pharmacology topics.

  • @francesca_rahkolli
    @francesca_rahkolli 2 ปีที่แล้ว +1

    Thank you for this! I'm learning a lot from you..

  • @Timtam973
    @Timtam973 2 หลายเดือนก่อน

    Another very helpful video! Thank you Zach!

  • @Self-Health-Evangelist
    @Self-Health-Evangelist 11 หลายเดือนก่อน

    Thank you for your time and help

  • @dinarmeltiara5456
    @dinarmeltiara5456 2 ปีที่แล้ว

    you did a very great explanation, cant thank enough 😭

  • @doc_matox
    @doc_matox 9 หลายเดือนก่อน +2

    Best TH-cam tutor ever❤❤❤

  • @samehabdel-hakam2026
    @samehabdel-hakam2026 9 หลายเดือนก่อน

    Dude! your videos are so damn underrated!! there should be millions of views! Wish those were available back when i was in college.

  • @taima899
    @taima899 11 หลายเดือนก่อน

    *******Just wonderful, I had all these concepts scrambled in my head until I watched these lectures.

  • @khalilahd.
    @khalilahd. 2 ปีที่แล้ว +1

    Thank you for this! 🙏🏽

  • @BaoTran-ls7oy
    @BaoTran-ls7oy 4 หลายเดือนก่อน

    Great explanation, thank you.

  • @raamishsiddiqui7330
    @raamishsiddiqui7330 ปีที่แล้ว

    You are literally THE BEST 💗💗💗life saviour

  • @albertobacci6265
    @albertobacci6265 ปีที่แล้ว

    very very helpful, thank you!!

  • @andrimartomasson5256
    @andrimartomasson5256 ปีที่แล้ว +2

    Thank you mr. Ninjanerd Sir. I have been leaning on my good friend and mentor, Vás, this semester. However, there are even gaps in his knowledge, as pharmacology is such a vast and complicated subject. You fill these gaps beautifully. May God bless you and the Ninjanerd team.

  • @mishkalmujjalla8286
    @mishkalmujjalla8286 2 ปีที่แล้ว

    Most respectfully sir
    Thanks for this videos free provide on you tube channel 👍

  • @gowharmajeed2329
    @gowharmajeed2329 ปีที่แล้ว

    You are best teacher in world

  • @HeiSoGzY
    @HeiSoGzY ปีที่แล้ว

    Ninja Thanks for Helping us break each and every Topic Down
    I'm Favour a Pharm D Student and a Very big fan of you, I just need only your videos and your videos Alone to understand any confusing Topic, Pls can you help us on Pharmacokinetics; the distribution part.
    Thank you Ninja nerd, we would really Appreciate it.

  • @diogoferreira109
    @diogoferreira109 ปีที่แล้ว

    omg beautifully explained

  • @miranabubakr5844
    @miranabubakr5844 25 วันที่ผ่านมา

    You drop this 👑

  • @invisibleblack7597
    @invisibleblack7597 ปีที่แล้ว

    Much love from Tanzania❤️

  • @niyadeo7970
    @niyadeo7970 10 หลายเดือนก่อน

    Amazing!!

  • @zaranabeel166
    @zaranabeel166 2 ปีที่แล้ว

    Thank you so much you, are literally saving my life
    I AM DESPERATELY BEGGING YOU I HAVE AN EXAM ON 15th PLEASE UPLOAD THE REST OF THE VIDEO :((
    I can not count on anyone but you, PLEASE

  • @juliamoretz1013
    @juliamoretz1013 ปีที่แล้ว

    You rock!! Thank you!!

  • @dibyasattwakarmakar
    @dibyasattwakarmakar ปีที่แล้ว

    Thank You, Sir

  • @vandhanachettiappillyhari5171
    @vandhanachettiappillyhari5171 ปีที่แล้ว

    Great explaination! Have you yet uploaded the next one about clearance and half life?

  • @shittuolamideayoola5687
    @shittuolamideayoola5687 ปีที่แล้ว

    Thank you🎉

  • @uroojfatima8361
    @uroojfatima8361 10 วันที่ผ่านมา

    Thankyouuuu so muchhhhh 🥹🫶🏽🫶🏽

  • @manalemad1589
    @manalemad1589 ปีที่แล้ว +1

    here comes the perfection ❤❤❤

  • @rayanisam6089
    @rayanisam6089 11 หลายเดือนก่อน

    It was very hard for me to understand this part of general pharma , thanks for benign a master of this 💓

  • @omersardar6896
    @omersardar6896 ปีที่แล้ว

    thank you so much

  • @22mooni
    @22mooni ปีที่แล้ว

    Thank you❤

  • @rayanthabit3489
    @rayanthabit3489 ปีที่แล้ว

    So so so exciting while watching..I hope pass the exam today
    BTW who is arabic here ?

  • @wajahatabbasi5673
    @wajahatabbasi5673 ปีที่แล้ว

    iAM big fan of you sir thank u so much

  • @mamalyfarahmand592
    @mamalyfarahmand592 ปีที่แล้ว

    when chemisrty plays an important role in clinical practice
    thanks Dr. Murphy

  • @hamzahajomar5614
    @hamzahajomar5614 ปีที่แล้ว

    Thank you

  • @mugheerafaizan5940
    @mugheerafaizan5940 ปีที่แล้ว +5

    As you explained in the "secretion" that if a drug is non-polar, hydrophobic, small it will be easier to filter into the tubules, but these are the same qualities that are needed to reabsorb anything back into the blood, if anyone can explain it to me in replies I'll be very thankful.

    • @rityomamaa
      @rityomamaa หลายเดือนก่อน

      Omg, finally someone with the same question. Have you found the answer yet? Because I don't get this either.

    • @mugheerafaizan5940
      @mugheerafaizan5940 หลายเดือนก่อน

      @@rityomamaa nope 😂

    • @mugheerafaizan5940
      @mugheerafaizan5940 หลายเดือนก่อน

      @@rityomamaa nope 😂

  • @PerfusionPrime
    @PerfusionPrime 2 ปีที่แล้ว

    Thank u ninja nerd

  • @2guptanshu
    @2guptanshu ปีที่แล้ว

    Thanks

  • @alaeharkasse7974
    @alaeharkasse7974 11 หลายเดือนก่อน +2

    Hello, can I know why the concentration of drug 2 gonna be high in the blood and low in the tubule? 10:38

  • @Val6035
    @Val6035 ปีที่แล้ว

    pharmacodynamics please!!! i have a test about it next wednesday!!!

  • @sahalturky9169
    @sahalturky9169 2 ปีที่แล้ว +2

    Thanks pro
    I'm from somaliland
    I learn more more.

  • @doctor9410
    @doctor9410 ปีที่แล้ว

    man v will donate once we start earning ❤…praying for your health 😊

  • @najiyounis9541
    @najiyounis9541 2 ปีที่แล้ว

    Thank u from libya

  • @nilkanthasharrma3455
    @nilkanthasharrma3455 2 ปีที่แล้ว

    Iam watching this video from Nepal

  • @zeeshanasif3051
    @zeeshanasif3051 2 ปีที่แล้ว

    Fantastic.please make videos on electrolyte disturbances.regards from pakistan.

  • @Medschoolsufferer
    @Medschoolsufferer ปีที่แล้ว

    @ninjanerds please do a video on Pharmacodynamics.

  • @resumezone
    @resumezone ปีที่แล้ว

    Literally i don't have enough words to appreciate your efforts 🙏

  • @mimiluna8195
    @mimiluna8195 ปีที่แล้ว

    I cant thank u enough

  • @karmagaming7112
    @karmagaming7112 ปีที่แล้ว

    Love u 3000 ❤️
    We are Ninja Nerds 🥷

  • @waseemakbar8435
    @waseemakbar8435 2 ปีที่แล้ว

    Almighty bless u ...

  • @ridabatool3525
    @ridabatool3525 2 ปีที่แล้ว

    Sir Zach, really hats off to you. You literally deserve more than 1 million subscriber💚

  • @lydiakaoudjt9369
    @lydiakaoudjt9369 ปีที่แล้ว

    The best

  • @ranosharoro9449
    @ranosharoro9449 3 หลายเดือนก่อน

    great love for you from iraq ❤️‍🔥

  • @AmnaSaeed-o3g
    @AmnaSaeed-o3g 27 วันที่ผ่านมา

    Please make video on autocoid

  • @2weeksago642
    @2weeksago642 ปีที่แล้ว

    How do I contact Ninja Nerd? I have a question regarding an illness that my brother has.

  • @amirabbasbaharfar2328
    @amirabbasbaharfar2328 ปีที่แล้ว

    Done.✅

  • @samisp4672
    @samisp4672 2 ปีที่แล้ว

    Do you have any video on pcos ?

  • @ranaumair4468
    @ranaumair4468 2 ปีที่แล้ว

    please make a video on jak inhibitors

  • @samiaridhi2668
    @samiaridhi2668 วันที่ผ่านมา

    Can u make a video list where you are discussing about the tricks of solving u world

  • @tasneemalhasan5317
    @tasneemalhasan5317 2 หลายเดือนก่อน

    I LOVE YOU

  • @clarinaackerman8639
    @clarinaackerman8639 28 วันที่ผ่านมา

    11:06 How could it possible that the concentration of the drug inside the bowman capsule are higher than the d.t.c.? Anyone please help me by explaining this

  • @michealraptor8424
    @michealraptor8424 9 หลายเดือนก่อน

    good sir where do you get your uestion from

  • @christiandad5920
    @christiandad5920 2 ปีที่แล้ว +1

    Bro how long did it take you to remember all this knowledge??! You have photographic memory? You make it easy to follow but bugger me if I remember it like you explain it.

  • @RidaBatool-id3fv
    @RidaBatool-id3fv หลายเดือนก่อน

    From where we can get this Lecture notes

  • @Syedhussein89
    @Syedhussein89 7 หลายเดือนก่อน

    Zach pls explain this …if a drug is coming from liver which has undergone phase 1 & phase 2 rxns…it becomes polar .. as u said …then how in kidneys the non polar drug molecules can be excreted out . ? It’s v confusing

  • @lordbishopkingmakercaraniu4118
    @lordbishopkingmakercaraniu4118 2 หลายเดือนก่อน

    I never understood the acid base effects before you

  • @bernadimalik8635
    @bernadimalik8635 10 หลายเดือนก่อน

    Are you sure that polar and nonpolar drugs are not confused with their molecular weight ? What I know is Polar drugs using Glomerular Filtration Rate have small molecule. **Im confused.

  • @shreyashnarade7566
    @shreyashnarade7566 2 ปีที่แล้ว

    Wow

  • @aasemahsan
    @aasemahsan 5 หลายเดือนก่อน

    15:39 Controlling overdose by preventing reabsorption ❤

  • @TheKellyMcAeer
    @TheKellyMcAeer ปีที่แล้ว

    6:55 is Secretion

  • @abcdefgh-lx3kz
    @abcdefgh-lx3kz 2 ปีที่แล้ว +1

    wow, that is atttractive man

  • @aayushbatra1147
    @aayushbatra1147 ปีที่แล้ว

    ❤❤❤❤❤❤

  • @lokeshhr8596
    @lokeshhr8596 2 ปีที่แล้ว +1

    bro can u plz do a vdo on pharmacokinetics introduction..

    • @brucedressel8873
      @brucedressel8873 2 ปีที่แล้ว

      Pharmacy the root word is the Greek word Pharmakeia which comes from the Hebrew word Kashaph which is Sorcery.

  • @missh6773
    @missh6773 ปีที่แล้ว

    I want to talk to you very important directly how could i do that please

  • @sumaiyaislam9377
    @sumaiyaislam9377 ปีที่แล้ว +1

    💙💙💙💙💙

  • @brucedressel8873
    @brucedressel8873 2 ปีที่แล้ว

    I have had 3 crainiotomies over the past 2.5 years. My body hates allopathic drugs the worst of which was dexamethasone what a crazy steroid this weirdness is.

  • @matthewpalumbo9357
    @matthewpalumbo9357 ปีที่แล้ว

    Dang you are smart

  • @user-nq4mw3cu4t
    @user-nq4mw3cu4t ปีที่แล้ว +1

    الصوره
    7:44

  • @bennydevinobenito2993
    @bennydevinobenito2993 2 ปีที่แล้ว

    Virtual Reality (VR) is a computer-generated environment with scenes and objects that appear to be real, making the user feel they are immersed in their surroundings. This environment is perceived through a device known as a Virtual Reality headset or helmet.
    Mixed reality (MR) is a user environment in which physical reality and digital content are combined in a way that enables interaction with and among real-world and virtual objects.
    Augmented reality is an interactive experience of a real-world environment where the objects that reside in the real world are enhanced by computer-generated perceptual information, sometimes across multiple sensory modalities, including visual, auditory, haptic, somatosensory and olfactory. Wikipedia

  • @mustafaadnan6120
    @mustafaadnan6120 2 ปีที่แล้ว +1

    We want histology lectures….please

  • @Drvlog307
    @Drvlog307 ปีที่แล้ว

    Plz sir in the end give 2 minutes to a quick review

  • @mayraconcepcion6815
    @mayraconcepcion6815 2 ปีที่แล้ว

    Marker drops.... Son of a Gun 😆🤣

  • @dler5360
    @dler5360 ปีที่แล้ว

    you're my jesus

  • @azielmalili6516
    @azielmalili6516 ปีที่แล้ว

    Boom roasted

  • @a.rathipal1334
    @a.rathipal1334 ปีที่แล้ว

  • @hamzahajomar5614
    @hamzahajomar5614 ปีที่แล้ว +123

    All of this is in our body's and there's people think that Allah is not exists

    • @noorkhaled1585
      @noorkhaled1585 9 หลายเดือนก่อน +7

      سبحان الله 👏

    • @fatimaahmed7909
      @fatimaahmed7909 9 หลายเดือนก่อน +20

      It's true he doesn't exist

    • @wandererrrrrr
      @wandererrrrrr 9 หลายเดือนก่อน +6

      سبحانك اللهم❤

    • @helabarby3922
      @helabarby3922 8 หลายเดือนก่อน +2

      Alhamdulila❤❤

    • @axdx2320
      @axdx2320 8 หลายเดือนก่อน +21

      Idk if it's sarcastic but couldn't you keep a belief seperated from a fact for an hour? Everything has a time and place.

  • @mittal6382
    @mittal6382 2 ปีที่แล้ว

    Hey ! Plz make a video on PULSE 🫀 in cvs it's the only one remaining and much needed..thanks