Pharmacokinetics | Drug Absorption

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  • เผยแพร่เมื่อ 1 มิ.ย. 2024
  • Official Ninja Nerd Website: ninjanerd.org
    You can find the NOTES and ILLUSTRATIONS for this lecture on our website at:
    www.ninjanerd.org
    Ninja Nerds!
    In this lecture Professor Zach Murphy will be presenting on Pharmacokinetics, specifically discussing drug absorption. We hope you enjoy this lecture and be sure to support us below!
    Table of Contents:
    0:00 Lab
    0:07 Drug Absorption Introduction
    0:43 Routes of Administration
    3:05 Mechanisms of Absorption
    10:26 Factors Affecting Absorption
    24:16 Bioavailability
    30:07 Factors Affecting Bioavailability
    39:14 Drug Absorption Practice Problems
    42:31 Comment, Like, SUBSCRIBE!
    Pharmacology Source:
    Whalen, Karen. Lippincott Illustrated Reviews: Pharmacology (Lippincott Illustrated Reviews Series). Wolters Kluwer Health.
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    / @ninjanerdofficial
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ความคิดเห็น • 305

  • @emiliolemoine5612
    @emiliolemoine5612 ปีที่แล้ว +282

    Zachary and the rest of the staff are literally saving my career. I will always be grateful to you for everything.

  • @genevievesimon
    @genevievesimon 8 หลายเดือนก่อน +53

    Ninja Nerd is literally the only reason I'm passing vet school. I cannot overemphasize how amazing and important this channel is!

  • @rahimarshad4191
    @rahimarshad4191 ปีที่แล้ว +88

    I've been using your videos for 2 years now and looking back at your older work vs now you guys have grown so much and In such positive direction too, the knowledge great as always, way of delivery keeps getting better and better. Can't afford it now but when I get a job I'll buy your subscription just to help you out. Keep up the good work.

  • @farahillahi...1466
    @farahillahi...1466 ปีที่แล้ว +60

    What a fortune to be born in a generation where teachers like u exist! Forever in debt for what u people are doin'! Bless up 👏

  • @kalilamartinsferrazlebrao3350
    @kalilamartinsferrazlebrao3350 ปีที่แล้ว +30

    This video almost brought tears to my eyes, pharmacology has been so hard for me and your videos make it so easy. Thank you, Zach

  • @anumek2606
    @anumek2606 ปีที่แล้ว +27

    Pharmacology is Love. Thankyou so much for this Zach. We want more, more and more pharmacology from you 👑

  • @ClaudiaSilva-xs3hq
    @ClaudiaSilva-xs3hq ปีที่แล้ว +4

    Zach and the whole staff are LITERALLY in my prayers. Can’t be more thankful ❤️

  • @Laura-xu5ev
    @Laura-xu5ev 3 วันที่ผ่านมา

    Thank you so much for these videos. 100% helping me through my NP program. The videos are entertaining and have a wealth of knowledge. My schoolbooks are dry and dull. Don't know what I would do without this channel. Keep up the excellent work :)

  • @lappelduvide2515
    @lappelduvide2515 ปีที่แล้ว +10

    Thank you so much for existing, you got me through my first year of med school and now you're getting me through the second 🥺

  • @ebubechukwuefo-anyasi3781
    @ebubechukwuefo-anyasi3781 ปีที่แล้ว +8

    God bless you Ninja Nerd. I was going to ask for pharmacology lectures and then boom... You're there already. Thank you for teaching me..

  • @madepatv96.
    @madepatv96. ปีที่แล้ว +3

    Thanks Zachary you are a life saver. I'm a sophomore nursing student. Your videos are top-notch. God bless you and your supportive team

  • @lucyberger7625
    @lucyberger7625 ปีที่แล้ว +1

    Thank you so much. I am an anaesthetic nurse doing my post grad and I am finding pharmacokinetics so difficult to wrap my head around. Your videos are really helping me understand pharmacology A LOT easier than what my lecturer could. So thank you!

  • @damilolaomoboriowo5589
    @damilolaomoboriowo5589 ปีที่แล้ว +2

    Thanks so much Zach. You're one of the reasons I've not completely lost in Med school. This is so simplified. Thank you🌹

  • @user-be9ds4kv2s
    @user-be9ds4kv2s 9 หลายเดือนก่อน +1

    I remember doing your biochemistry lectures, and it took me forever to draw out your lectures. I just became a member, and I love your templates. Amazing. The best part is that your price is the lowest of any med school resource I have bought. Thank you

  • @ghostemane3209
    @ghostemane3209 ปีที่แล้ว +2

    I’d be lost without you. Best teacher I ever had. Thank u a million times Zack and keep on teaching us!!!

  • @Timtam973
    @Timtam973 21 วันที่ผ่านมา

    So grateful to you. You are not only extremely knowledgeable but one of the most capable people on TH-cam, to pass on your knowledge. Amazing series.

  • @melpinhattischisler994
    @melpinhattischisler994 ปีที่แล้ว +1

    You guys are incredible!!! Such amazing resources/classes. I have been using ALL your material for my nursing degree. A huge thanks from Florianópolis, Brazil!

  • @noahelia1579
    @noahelia1579 ปีที่แล้ว +49

    Really appreciate you going into pharmacology a little more on this channel! Great content as usual:)

  • @SuperAmir101
    @SuperAmir101 9 หลายเดือนก่อน +6

    I absolutely love these knowledge check questions at the end of the videos!! Please utilize more of these types of questions at the end of all your videos in the future!! :) and maybe some case applied USMLE-type practice questions would be so cool and helpful too!! And I cannot thank this channel enough, such a great work by Zach and his entire team and wishing you all the growth and success because y’all deserve it as you’ve made many of us successful in our studies and careers!! Thank you Ninja Nerd Team!! :)

  • @abdullahbholat2626
    @abdullahbholat2626 9 หลายเดือนก่อน

    Starting my first pharm class for crna school. I appreciate everything you do in all your videos

  • @Teee_studies
    @Teee_studies 4 หลายเดือนก่อน

    Zach someday, somehow in my life I promise myself I’m going to meet you in person. You’re incredible, extraordinary, a mavin. I got an A in pathology and most credits goes to your lectures Zach.

  • @mikki-loramartinez1344
    @mikki-loramartinez1344 4 หลายเดือนก่อน

    It's 3 lectures in one, so focused and understandable. Thank You so much for your videos❤❤❤

  • @Sam-yi6hp
    @Sam-yi6hp 3 วันที่ผ่านมา +1

    So lucky to have u thank you so much sir 💕

  • @kaushikdas7412
    @kaushikdas7412 ปีที่แล้ว +6

    sir, i would like to ask you , if you can please make few videos on clinical topics , eg: on opthalmology or otorhinolaryngology, medicine etc with clinical aspect & details . It would be extreamly helpful for us after passing pre-clinical years. I have completed my pre-clinical years watching your videos and they have helped me soooo much. Thanking you.
    love your videos❤️

  • @garipovdin
    @garipovdin ปีที่แล้ว

    Thanks a lot. You and you crew create something beautiful every time. We really appreciate it!

  • @pabloaureliopaucarcajayaya3109
    @pabloaureliopaucarcajayaya3109 ปีที่แล้ว +1

    We all future physicians love you my man 👊 GREAT LECTURE!

  • @user-wi3sm8sn6q
    @user-wi3sm8sn6q 8 หลายเดือนก่อน

    ninja you are really the best teacher who exists in this era where the teachers are not sincere with their professions

  • @rayanthabit3489
    @rayanthabit3489 ปีที่แล้ว +4

    While am watching I feel very very exciting to now what happend and feel like I well take all night watching ur videos about pharmacy .. oh thanx our friend and doctor❤❤ how can we thank you❤❤☘

  • @taima899
    @taima899 9 หลายเดือนก่อน +1

    You guys are awesome!!!!! I've been reading and everywhere it's so dense that I get lost in so much fancy terminology. You made it so easy to digest, thanks

  • @lostalunatic
    @lostalunatic ปีที่แล้ว +1

    Thank you, from a dietetics student this is wonderfully condensed

  • @AnastasiaLane-lj6hk
    @AnastasiaLane-lj6hk หลายเดือนก่อน

    I finally understand lipid soluble and water soluble. Thank you.

  • @ahsanjalil9486
    @ahsanjalil9486 ปีที่แล้ว +3

    Hey zach thank you so much for doing this much effort in teaching us . love your videos a whole lot .

  • @rifathasan1325
    @rifathasan1325 ปีที่แล้ว

    I 'll be grateful to you for your kindful work..your explanation process makes tough things crystal clear to me.

  • @zarinsaiawara6007
    @zarinsaiawara6007 ปีที่แล้ว

    Back again after my 1st prof...4th year pharma took my soul,,bt suddenly remember,, ninja nerd still Being an angle❣️lots of doa for u guys

  • @ETR.02
    @ETR.02 ปีที่แล้ว +8

    Great content!!! I'm so glad you're doing pharma courses as well :)

  • @manalemad1589
    @manalemad1589 ปีที่แล้ว +3

    thank u so much you r simplifying all the topics for us ❤❤❤❤❤

  • @teresavalencia1633
    @teresavalencia1633 ปีที่แล้ว +1

    Bless your soul Ninja Nerd! Your videos really make everything make sense.

  • @sophiaB270
    @sophiaB270 ปีที่แล้ว

    This is the first of your videos that I am watching....WOW. That was AMAZING. All of a sudden, as if by magic, i understand literally everything you said. Thank youuuuu!!!

  • @jyothiuddandravu3835
    @jyothiuddandravu3835 ปีที่แล้ว

    There is no Words to describe how amazing the videos and u. It's like u know every topic and everything u guy are phenomenal

  • @smick9081
    @smick9081 2 หลายเดือนก่อน

    the enthusiasm about the topic 100% made me more engaged, which is definitely difficult with my severe ADHD diagnosis, good work ninja, youve caught the attention of the adhd ones, i vant get over the enthusiasm, definitely made me feel more in an actual class, love the effort!

  • @brunnaaraujo7056
    @brunnaaraujo7056 8 หลายเดือนก่อน

    I'm truly happy that I found this class!

  • @esrasaroori2048
    @esrasaroori2048 ปีที่แล้ว

    Really thank you for making everything simple and absorbable 👏🏼

  • @blackyrocky7438
    @blackyrocky7438 ปีที่แล้ว +1

    A long awaited video is here! Thanks for making this happen. 👍👍👍

  • @neginyahyazadehmashhadi1576
    @neginyahyazadehmashhadi1576 10 หลายเดือนก่อน

    the part you explaing about ph effect on absorption has been always confusing for me, now you have made it so clear .thank you so much

  • @medoxhunter6699
    @medoxhunter6699 9 หลายเดือนก่อน

    I really want to thank you all for this great job and these great lessons I was almost given up from studying pharmacology again but you saved me your lessons are easy to understand informative and helpful thank you for your efforts

  • @zukisatshabalala3198
    @zukisatshabalala3198 ปีที่แล้ว +3

    So happy that you have started a pharmacology series! Will make sure my students have the links.

  • @aol860
    @aol860 ปีที่แล้ว

    I just want to thank you. I am now a EEN and your videos taught me so much. Thank you 🌹🙏

  • @menapaul1308
    @menapaul1308 ปีที่แล้ว

    You’re the man! You teach this better then all my professors!!!

  • @ThunderBunBun
    @ThunderBunBun 8 หลายเดือนก่อน +3

    This video is much more useful than my 3 hours lecture

  • @vencemuchera7601
    @vencemuchera7601 8 หลายเดือนก่อน +1

    Thanks sir , pharmacokinetics was a challenge but after this lecture i have shared with my friends and they are so happy thanks for the knowledge be blessed

  • @hibakamran3554
    @hibakamran3554 ปีที่แล้ว

    thank you so much dr zach for this brief revision ..... 😇

  • @Mariatyra
    @Mariatyra ปีที่แล้ว

    thank you so much for taking the time to explain this in depth

  • @severussnape2134
    @severussnape2134 ปีที่แล้ว

    You're a lifesaver. Thank you for all that you do.

  • @doctor9410
    @doctor9410 ปีที่แล้ว

    got the whole concept 110%…tnx man

  • @user-pm2gs6xf3z
    @user-pm2gs6xf3z 11 หลายเดือนก่อน

    AMAZING!!! thank you! Love the questions to check understanding. You're the best and I appreciate your time and knowledge!!!

  • @inorirain7323
    @inorirain7323 ปีที่แล้ว

    I'm so grateful for the pharmacology video. Thanks!

  • @Shelby-ls9wf
    @Shelby-ls9wf ปีที่แล้ว

    You're the best. Thank you so much for helping me understand. Your hard work is very appreciated

  • @shahedshasani4939
    @shahedshasani4939 ปีที่แล้ว

    this is probably one of the most important concept when it comes to bioavailability

  • @adamwalsh1977
    @adamwalsh1977 ปีที่แล้ว

    Amazing teaching on a VERY in-depth subject matter. Thank you so much, easy 2 follow easy 2 understand 👍🏻

  • @BoredT-Rex
    @BoredT-Rex ปีที่แล้ว +3

    Awesome. It would also be cool to mention halflives and zero order kinetics with examples vs first order kinetics

  • @jasmenea2514
    @jasmenea2514 ปีที่แล้ว

    I loved the questions at the end of the video!!! Thank you for all your hard work and dedication!!!!

  • @chelseathesciliber2501
    @chelseathesciliber2501 5 หลายเดือนก่อน

    Nahhhh not me crying everytime I'm tryna study pco buh with just this one I'm loving the course alreadyyyy u make it Soo easy bruh🥺😭♥️

  • @greenmaple7496
    @greenmaple7496 ปีที่แล้ว +3

    Hi, thanks for all the great content! I would like to know how our nervous system works when we sleep. is there any of ur video could help explain? thanks! Ninja Nerd

  • @tasfia9787
    @tasfia9787 4 หลายเดือนก่อน

    14:50
    Amphitamine-intestine(weak alkaline)
    Aspirin-proximal duodenum(weak acid)
    22:00
    32:00

  • @adityab.v.2832
    @adityab.v.2832 2 หลายเดือนก่อน

    Informative and relevant live Absorption of drug class by Professor Zach than many of my attended college lectures.

  • @asthashah13
    @asthashah13 ปีที่แล้ว

    It's so good to find you sir. You're the best. Keep helping and guiding us. Love from india❤

  • @marcosdominguez4130
    @marcosdominguez4130 ปีที่แล้ว

    It simply the best medical professor in the internet right now

  • @bobkindson3914
    @bobkindson3914 ปีที่แล้ว

    Thanks Ninja Nerd, patiently waiting for the other topics under Pharmacokinetics

  • @larishsa8816
    @larishsa8816 ปีที่แล้ว

    Because of you, I am confident that I will pass my PEBC EXAM.

  • @doc_matox
    @doc_matox 7 หลายเดือนก่อน

    Thank you so much for this fantastic video Prof. Zac

  • @ilariabelluco1826
    @ilariabelluco1826 ปีที่แล้ว +1

    I love you Doctor Murphy

  • @user-xx7ed7ti1z
    @user-xx7ed7ti1z ปีที่แล้ว +1

    Hi Zach, totally appreciate the lecture.
    Just a question, whoever can answer I'm thankful: you say "area under the curve", but you measure in mg for the bioavailability formula. Are we comparing the surface area or the milligrams of whatever gets into circulation? Thank you! Keep up the awesome work 👍

  • @esmalyaharyuni2240
    @esmalyaharyuni2240 ปีที่แล้ว

    Amazing explanation! Thank you so much!

  • @dishanthsrideva7196
    @dishanthsrideva7196 ปีที่แล้ว

    Ninja nerd team thank you for some great quality of content, keep it coming and all the best 🙌🙏

  • @seharkhalid9013
    @seharkhalid9013 7 หลายเดือนก่อน

    I have no words to appreciate your efforts and hardwork. Your are really very veerry very amazing teacher. My hearties prayers are always there for your success and peace of life. Thank you sooooo much for doing alot of work and delivering us such valuable knowledge in free of cost. Allah will definitely bless you with the greatest rewards in this world and the world after

  • @Achini94
    @Achini94 ปีที่แล้ว

    I am visual lerner and your vedios really useful to me.Thank you soo much. Love from SriLanka💕

  • @sohrabkhan3233
    @sohrabkhan3233 ปีที่แล้ว

    Thank you so much waiting for further videos on distribution,excretion and then pharmacodynamic 😍😍

  • @luna-heyyy
    @luna-heyyy ปีที่แล้ว

    i wish you were our professor at uni !!!! ours is just reading the slides he wrote YOU ARE AMAZING THANK YOU SO MUCH

  • @m.shaker1639
    @m.shaker1639 4 หลายเดือนก่อน

    Ninja Nerd is literally a legend

  • @mamalyfarahmand592
    @mamalyfarahmand592 ปีที่แล้ว

    i dont know what to say im just writing a comment to support the channel for future contents.
    thanks for your commitment and dedication to science

  • @ethiomuslimssociety3596
    @ethiomuslimssociety3596 ปีที่แล้ว

    Ninja looking forward this for my pharmacology class and Am very happy that because the video is from you and please do more on others( Distribution Metabolism excretion)

  • @mosesnchimunya8136
    @mosesnchimunya8136 ปีที่แล้ว

    This is beautiful, kindly make videos on the effects of anesthetic drugs, will really appreciate.

  • @munibullah3114
    @munibullah3114 หลายเดือนก่อน

    Thanks sir , it's very helpful

  • @sasisasi-gn7xk
    @sasisasi-gn7xk 22 วันที่ผ่านมา

    really you did great job.,, thank u so much 🙏

  • @bielulhaileab9128
    @bielulhaileab9128 ปีที่แล้ว

    It was at time. Big fan of you. Thanks so much. Will you also give a lecture on the mechanism of action of antibiotic resistance?

  • @sedooamase6423
    @sedooamase6423 ปีที่แล้ว

    Thank you sir, very detailed. Easy to understand.

  • @zurassik_paarc
    @zurassik_paarc ปีที่แล้ว

    Hi Ninja Nerd ... I am big big fan of you and your hardworking team ... Which brings excellent content on regular basis ... Thanks alot for existing

  • @sweet_sabamed001
    @sweet_sabamed001 ปีที่แล้ว

    perfectly clear, thank you ninja nerd

  • @dr.favourkalu6480
    @dr.favourkalu6480 ปีที่แล้ว +1

    Thank you so much Zach,You are the best 👌

  • @pratibhacdri
    @pratibhacdri 3 หลายเดือนก่อน

    Amazing lecture. I am wondering what happens to the drug given by the intraperitoneal (IP) route, as we do frequently in mice? I would like to know more about this from you. Thank you.

  • @luciaperez1832
    @luciaperez1832 ปีที่แล้ว

    alwayx excellent!!! Please make more videos about pharmacology. Love

  • @bizcaya
    @bizcaya ปีที่แล้ว

    Huge thank you! You guys are awesome🎉

  • @mateussilvaviyuela8953
    @mateussilvaviyuela8953 ปีที่แล้ว

    Spetacular class🎉🎉 Watching from São Paulo, Brazil 🇧🇷

  • @inayetullahqadir90
    @inayetullahqadir90 ปีที่แล้ว

    much love n respect dear sir❤️❤️

  • @nsaidzekacyril6962
    @nsaidzekacyril6962 ปีที่แล้ว

    Thanks so much Ninja nerd. I've learned a lot from this video. Much love from Cameroon

  • @peterchilufya8265
    @peterchilufya8265 หลายเดือนก่อน

    You're the best of the best. You've really served me

  • @user-dn8fk3mw8i
    @user-dn8fk3mw8i ปีที่แล้ว

    so easy and clear. Thanks doc

  • @user-yg2nr5uy4b
    @user-yg2nr5uy4b 7 หลายเดือนก่อน

    my gosh you are so good at explaining it..i understood it so well!! love your videos :)

  • @ngozisoph
    @ngozisoph ปีที่แล้ว

    Thank you for this.
    Interesting to watch.
    Simplified to the T

  • @kabouch
    @kabouch 11 หลายเดือนก่อน

    36:58 You may be correct when you say that only drugs administered by the oral route undergo first pass metabolism in the liver, but this doesn't necessarily mean that drugs administered by other routes are not subjected to 1st pass effect via intracellular and extracellular enzymes at the site of absorption.