Purine and Pyrimidine Degradation

This video explains the degradation of purine nucleotides into their excretory product uric acid. Purine nucleotides are degraded using 5' nucleotidase, AMP deaminase, purine nucleoside phosphorylase, xanthine oxidase into their end product uric acid. Uric acid is excreted by the kidney into urine. Purine salvage pathways for both purines and pyrimidines. Purine salvage pathway and pyrimidine salvage pathway are beneficial for the cells because these salvage pathways saves energy and time for the cells. utilization of free bases or nucleosides and salvaging them into purine nucleotides or purine nucleotides or pyrimidine nucleosides or pyrimidine nucleotides help the cells to save energy and time. Different enzymes are involved in purine salvage pathway and pyrimidine salvage pathways. Two disorders to mention related with salvage pathway are Lesh-Nyhan syndrome and severe combined immunodeficiency disease.
Links for my other videos on purine metabolism and pyrimidine metabolism
Purine synthesis
• Purine Synthesis (De N...
Regulation of purine synthesis
• Purine Synthesis Regul...
Pyrimidine synthesis
• Pyrimidine synthesis d...
Regulation of pyrimidine synthesis
• Pyrimidine Synthesis R...
Ribonucleotide reductase
• Ribonucleotide reducta...
Gout
• Gout - Biochemistry an...
Link for Lesch-Nyhan syndrome
• Lesch Nyhan Syndrome
Link for severe combined immunodeficiency disease
• Severe Combined Immuno...
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[@bilquisara8582]

Sir u save my lot of time by explain this topic biosynthesis n degradation of purine .....I waste my hole day on other vdos still can't understand ....thanks alot

[@bilquisara8582]

Sir make more n more vdos it really helped a lot of people n students , teachers , parents ,,in short everybody

[@aqidahkhariri5046]

I've watched many of your videos. Thank you so much.. Your videos really help me understanding biochem

[@DrMungli]

You are most welcome. I'm glad these videos are helpful to you.

[@malikamalli1453]

It's only define on purine degradation...... But your heading is purine and pyridimine degradation... And I watched ur 1st vdo... It's Good and clear explanation

[@riteekakdas7740]

Thanks a lot sir...your videos have ignited my interest in the subject...I do not have to look into any of the books now...your videos are more than enough in understanding everything...

[@udaikumar2680]

Very good explanation

[@prabhutvachaturvedi3186]

Thankyou bhai

[@silentnight8346]

ur videos are vv helpful and great 😙

[@DrMungli]

Thank you. I'm glad you have found these videos helpful.

[@silentnight8346]

thanks alot sir ... sr plz appload videos about DNA and RNA BIOCHEMISTRY LICTURES

[@DrMungli]

I will try though I don't actively teach these topics since few years.

[@dr.alicejayapradabiochem8812]

Sir, why AMP can't be converted to Adeninosine as GMP is converted to Guanosine

[@user-qu4kb7wx1m]

Sir where is pyrimidine degradation video

[@medicogivemered9221]

Sir.mkae video on free radical.

[@akshayjouhary3897]

Good job ❤

[@Ramkumar-nj9mi]

Where is pyrimidine

[@DrMungli]

Brief explanation for pyrimidine degradation starts at 13:08 minutes

[@Ramkumar-nj9mi]

Dr.Mungli u explained purine..which is really easy...but pyrimidine is little bit complicated....u need explain them in the board sir

[@ritusingh4184]

Ram kumar 8

[@babbi2549]

why GMP not converted to IMP

[@DrMungli]

GMP is not converted to IMP

[@yasirmohammedali]

Hi

[@aaykumar-tf6gy]

Sir plz make video on enzymes based on qus. And also different type competitive inhibitor, and also allosteric enzmes.

[@DrMungli]

Sure I will try to make more videos on enzymes.

[@sarajp9150]

Hey. Thanky you. I have a question. Why pyrimidne nucleosides have more thermal stability than purine nucleosides?

[@Gnokhi]

Nice... Thank u...
Not to be a sticker.. but isn't ammonium ion NH⁴+.. and not NH³+...??

[@ArisingCapitals.]

Sir , according to me you should have to explain pyrimidine degradation as brief like purine

[@mehakrubab2727]

Thabku sir plz make a lecture on bone markers aswell