Metabolism | Nucleotide Synthesis | Purine & Pyrimidine Synthesis

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  • เผยแพร่เมื่อ 28 ก.ย. 2024
  • Official Ninja Nerd Website: ninjanerd.org
    Ninja Nerds!
    In this lecture Professor Zach Murphy will be discussing Nucleotide Synthesis! We go into detail on purine and pyrimidine synthesis that will ultimately be the chemical groundwork for building RNA and DNA! We hope you enjoy this lecture and be sure to support us below!
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    #ninjanerd #NucleotideSynthesis #Metabolism

ความคิดเห็น • 837

  • @sabahalezaireg9023
    @sabahalezaireg9023 2 ปีที่แล้ว +114

    I think you are a gift from God to not only medical students, but also to people who cannot afford to get private tutors because I think your teaching is at the highest level of private tutoring. Thank you Sooooooooooooooooooooooooooooooooooo much and may God bless you with everything you do in this life because you are a life changer.

  • @andrewjames2475
    @andrewjames2475 3 ปีที่แล้ว +50

    I can't begin to describe how incredibly helpful you have been during my first year of medical school so far. Thank you so much I hope you are staying safe during these crazy times!

  • @asjsjsienxjsks673
    @asjsjsienxjsks673 3 ปีที่แล้ว +593

    Dude you're performing a public service. What an absolute legend. Seriously, whenever there's something I don't understand I search for your videos. Your videos are hands down, better than 95% of all university lectures. You should be very proud of the work you do. Thank you!

  • @rahafsay5708
    @rahafsay5708 3 ปีที่แล้ว +30

    Gathering all this information in 45 minutes while making it fun and easy to study is so much work I appreciate this so much

  • @alexisadams6956
    @alexisadams6956 2 ปีที่แล้ว +27

    I flipped through so many videos and they only confused me....I understood this and I actually enjoyed it, you had me laughing at times. Thanks, just a million thanks. I for sure am passing my test now!

  • @tannerandkadimaxfield7533
    @tannerandkadimaxfield7533 3 ปีที่แล้ว +25

    You are the man, Zach. Thank you for everything you do bro. I cannot tell you how many times I have left lecture (even now as a grad student) frustrated with how content was presented and feeling like I didn’t understand what was being taught. But then my next thought is, “yo, I bet NinjaNerd Lectures has something about this..” and every time, without fail, you manage to get me back up in the saddle. I owe a lot to you and your passion for science. Thank you again, Broskee.

  • @narsisazarian687
    @narsisazarian687 9 หลายเดือนก่อน +4

    you're truly my hero. i have a biochemistry exam and i was knocked out. your videos are literally saving me. even though english isn't my mother tounge, i understand you way more than my own teachers. I pray for you a lot. hope you're always healthy and happy.

  • @dr.malpraxis
    @dr.malpraxis 4 ปีที่แล้ว +78

    Finally,a lesson that I've been looking for. Thank you.

    • @Zoe_EK
      @Zoe_EK 4 ปีที่แล้ว

      Yes! I remember it was the worst part to learn of my metabolism lecture 2 years ago😂 That video would have been great to have an overview of the whole complex system!

  • @cme1447
    @cme1447 4 ปีที่แล้ว +42

    Hi ninja nerd, it’s amazing how many videos With so much passion you do! Are you doing this just for fun, just because you want to help people? You’re not even putting ads!It’s amazing

  • @jennifermarcenelle5309
    @jennifermarcenelle5309 หลายเดือนก่อน +1

    I am a medical student in Chicago taking a 5,000 level biochemistry course - when I count my blessings I COUNT YOU TWICE!!!❤

  • @kristeljademiranda5983
    @kristeljademiranda5983 2 ปีที่แล้ว +3

    I never ever skip ads when I watch your videos. You're a life saver! Thank youuu

  • @itsmefatimah
    @itsmefatimah 4 ปีที่แล้ว +5

    Your explanation during this time really helpful since all of my lecturers just reading their slide without further explanation due to the limited medium of communication during this quarantine time. Thank you Sensei!

  • @lavemrai6880
    @lavemrai6880 4 ปีที่แล้ว +14

    I have been sharing your videos to all my friends preparing for their exams.
    Hope that gets you more views and subs (thats all i can do from my side right now :D )
    Thank you so much for making medicine easy!

  • @chandanabudur2434
    @chandanabudur2434 3 ปีที่แล้ว +3

    Zachary bro, you are a gift from heaven, I'm so lucky to be born in this era❤️❤️

  • @leobehrendt6177
    @leobehrendt6177 4 ปีที่แล้ว +2

    You guys are the best! Thank you for all the content you are providing for free. I really appreciate the fact that a channel like yours exists. The information density and quality of your videos is unmatched.

  • @walidsanallah
    @walidsanallah ปีที่แล้ว +1

    What a Legend. I think all med should just make students watch your video and USMLE score will be way better. I have learned way more from you videos that I have during any lecture during my med school. you should be recognized by all med school and USMLE bored. Thank you tons.

  • @victoriaezembu4509
    @victoriaezembu4509 ปีที่แล้ว +4

    Thank you so much Zach. You have no idea how helpful you’ve been to me❤

  • @mohammedahmedjalloh531
    @mohammedahmedjalloh531 4 ปีที่แล้ว +8

    I have finally completed the metabolism video series.. wasn't an easy journey but it was worth it.. thanks Zack and Co.. Looking forward to more of these metabolic pathways. Thanks To THE TEAM IN GENERAL

    • @klaraholesovska2089
      @klaraholesovska2089 3 ปีที่แล้ว

      Same here :D It was more like a "metabolism marathon" but still very much worth watching/studying. Thank you!

  • @carl247-n8q
    @carl247-n8q 2 ปีที่แล้ว +1

    live long legend the videos are making my understanding in biochem more easier

  • @DrT02
    @DrT02 8 หลายเดือนก่อน +1

    Before even starting the video, I first hit the like button…. Because I know it’s gonna be LEGENDARY 😍😍😍🤩🤩🤩 ALL HAIL DR. ZACH AND THE NINJA NERD TEAM ❤❤❤❤❤❤❤❤❤❤❤❤

  • @Slicc_Vicc_
    @Slicc_Vicc_ 4 ปีที่แล้ว

    This guy made such a complicated topic so comprehensible and entertaining!

  • @tayyabahussaini7218
    @tayyabahussaini7218 4 หลายเดือนก่อน

    there are no words that can pay you appreciation

  • @sugarchoux_23
    @sugarchoux_23 4 ปีที่แล้ว +2

    OMG THANK YOU FOR UPLOADING THIS!!! I tried to read slides from my uni but i still confuse about nucleotide metabolism. Your video really help me. Thank you!

  • @cynthia2936
    @cynthia2936 2 ปีที่แล้ว +3

    yo creo que me fue bien en mi examen y aprobé bioquímica de puro ver esta playlist, gracias mi rey ninjanerd 🌹💗

  • @AGrant-eb5mr
    @AGrant-eb5mr 4 ปีที่แล้ว +1

    You make it look so easy. And, it makes sense in a sensible way. Thanks!

  • @gloriasolomon6165
    @gloriasolomon6165 3 ปีที่แล้ว

    This guy is has helped me so much in my preclinical
    This is the only channel where am gonna join Patreon ! God bless you abundantly

  • @yumnabeeha
    @yumnabeeha 11 หลายเดือนก่อน +2

    How does he remember everything like everything!!??

  • @shellbeinginaction777
    @shellbeinginaction777 4 ปีที่แล้ว +2

    I'm studying for my Biochem Intensive final tomorrow. Thank You!!!!!

  • @meilaniekaputri1748
    @meilaniekaputri1748 3 ปีที่แล้ว +1

    Thank God, all of ur works really helped me a lot surviving uni lectures that's really hard to understand:")

  • @aniketpatra8514
    @aniketpatra8514 3 หลายเดือนก่อน

    Your videos really helps me to understand Biochemistry....thanks a lot sir

  • @birungipriscilla1670
    @birungipriscilla1670 2 ปีที่แล้ว

    you are a typical example of a genius... you so good thank you somuch

  • @storm4attoaster248
    @storm4attoaster248 ปีที่แล้ว +3

    you sir made this subject a heck of fun by making it understand in a fun way
    I can only thank you for your service....

  • @sheilaayusyafitri1932
    @sheilaayusyafitri1932 4 ปีที่แล้ว

    I'm a chem student and you literally helped me aced my biochem courses! now I'm taking molecular biochemistry and I LOVE IT WHEN YOU SAID "appreciate you sticking by through whatever the heck this is" lol yas, that's literally biochem and orgo to me

  • @DaSpeedster
    @DaSpeedster 4 หลายเดือนก่อน

    Bro you’re so good at this fr, bless ya!

  • @vansremin1132
    @vansremin1132 2 ปีที่แล้ว

    Again I fall in love with the minute i listened your lectures zachhhhh 💜

  • @yasheegupta6144
    @yasheegupta6144 4 ปีที่แล้ว +1

    Thank you ,you make these crazy topics seem a piece of cake.

  • @Any-Time-Just-Chill1991
    @Any-Time-Just-Chill1991 ปีที่แล้ว

    Thanks sir for your great assist, may God keeps you always healthy and more capable to serve to young doctors.
    Your student from Afghanistan.

  • @chuolwugokii
    @chuolwugokii ปีที่แล้ว

    You're a hero Dr.N, May God bless you more abundantly.

  • @Benitahbherosecondchannel
    @Benitahbherosecondchannel 2 ปีที่แล้ว +1

    The reason I'm passing biochemistry tbh. Thank you for your videos!

  • @Xtutors
    @Xtutors 8 หลายเดือนก่อน

    You’re saving my life here 😫thank youu

  • @hayaalmly6083
    @hayaalmly6083 3 ปีที่แล้ว

    Finally, I am able to digest nucleotide metabolism! Thanks!!!

  • @ThuongHoang-uz3gv
    @ThuongHoang-uz3gv 3 ปีที่แล้ว

    I’m a big fan of your paint. I love the way you show the lessin, it totally attacks me. ❤️ from Vietnam

  • @BarakatYusuf-x4k
    @BarakatYusuf-x4k 4 หลายเดือนก่อน

    Thank you😩😩😩💔 I'm literally having this test in about 10 minutes❤❤

  • @victoriaverville3609
    @victoriaverville3609 3 ปีที่แล้ว

    Dont know what Id do without you guys! Thank you!!

  • @sumitakundu8442
    @sumitakundu8442 ปีที่แล้ว

    Thank you for this beautiful video,I have a request, please make a video on the mechanism of ribonucleotide reductase

  • @raqiibahissa4393
    @raqiibahissa4393 2 ปีที่แล้ว

    I am so obsessed with these videos😍, kindly explain the biochemisty of gout and hyperuricemia

  • @dwightjones9580
    @dwightjones9580 ปีที่แล้ว

    Now that I'm older. I would have much rather mastered this knowledge rather than scoring touchdowns and making jump shots, and hitting home runs!!!

  • @agashibarnabas
    @agashibarnabas 10 หลายเดือนก่อน

    Thank you very much sir , you really made me understand this course

  • @tomastrpak9523
    @tomastrpak9523 3 หลายเดือนก่อน

    you really are a lifesaver, thank you

  • @khadijababaganafannami2804
    @khadijababaganafannami2804 3 ปีที่แล้ว

    You are truly a life saver🥷🏻🤓 salute

  • @noorullhadinoori9412
    @noorullhadinoori9412 ปีที่แล้ว

    İ don't have the words to appreciate but
    Thank you sir

  • @GiAndrei97
    @GiAndrei97 3 ปีที่แล้ว

    I do my anki cards during lecture time, watch ninja nerds videos afterwards to a faster, clear cut explanation for biochemistry! Thank you!

  • @nomanasim8903
    @nomanasim8903 2 ปีที่แล้ว +1

    Thankyou so much ninja nerd for this explaination,stay blessed and keep making these informative videos ❤️

  • @FadilaAbdullahiMainasara-xu2zs
    @FadilaAbdullahiMainasara-xu2zs ปีที่แล้ว +1

    Amazing lecture

  • @manalemad1589
    @manalemad1589 ปีที่แล้ว

    thanks a lot for the greatest team
    this is a work of art

  • @IndraneelMazumdar-c9g
    @IndraneelMazumdar-c9g 5 หลายเดือนก่อน

    Crystal clear concepts thanks a lot ❤.

  • @ThuongHoang-uz3gv
    @ThuongHoang-uz3gv 3 ปีที่แล้ว

    I’m a big fan of your paint. I love the way you show the lesson, it totally attacks me. ❤️ from Vietnam

  • @Hammod227
    @Hammod227 4 ปีที่แล้ว +1

    Was great explanation! Just have one question, if both AMP and GMP are present in adequate amount the de novo pathway of purines synthesis is turned off at the amidotransferase step? Why this occur at this step?

  • @RosevalerieBusie
    @RosevalerieBusie 3 ปีที่แล้ว

    Thanks for making our life easy😊😊

  • @microwavedoeswonders5741
    @microwavedoeswonders5741 2 ปีที่แล้ว

    Good God. So extensive yet fruitful.

  • @wasim_fatmi
    @wasim_fatmi 4 ปีที่แล้ว +1

    This channel is superrrrrbbbbb...amaaazzzziiing... very helpfull... for us....thank uuuuuuuuh very much...Sir...✍️♥️

  • @gautammure
    @gautammure 2 ปีที่แล้ว +1

    Excellent, my boy! As usual. Small corrections :
    1. Uridine not Uritidine. I think you were reminiscent of Cytidine ;)
    2. After PRPP joins in with Orotate, a pyrophosphate [PPi] is popped of leaving behind the phosphoribosyl part onto the nitrogenous base precursor, forming Orotidine Monophophate.

  • @boburhamidov3770
    @boburhamidov3770 7 หลายเดือนก่อน

    The GOAT of Biochemistry)

  • @gibriljallow1780
    @gibriljallow1780 4 ปีที่แล้ว +1

    Wow!!! I can't thank you enough.
    God bless you...

  • @prasathsampath2505
    @prasathsampath2505 2 ปีที่แล้ว

    Oh sir, you make our every day lectures much better with your brilliant explanations 😃😍 Thankyou so much sir ❤️🇱🇰

  • @emineaydogdu7097
    @emineaydogdu7097 3 ปีที่แล้ว +2

    Wish you also explained salvage pathway, still great video as always

  • @nampotiwong9863
    @nampotiwong9863 3 ปีที่แล้ว

    thanks god Ninja Nerd exist, I don"t have to read millions of textbook pages

  • @smritimondal1057
    @smritimondal1057 ปีที่แล้ว

    Thanks man, you're really the goat

  • @aydaabdolmanafi
    @aydaabdolmanafi 3 หลายเดือนก่อน

    Finally a word from the man behind the scenes😂

  • @alive680
    @alive680 3 หลายเดือนก่อน

    You are perfect , Thanks God I found your Video

  • @EllyOmondi-ls6xi
    @EllyOmondi-ls6xi 6 หลายเดือนก่อน

    Ooooh that was superb, I loved it👍🤝

  • @FarhanKhan-kx4yh
    @FarhanKhan-kx4yh 3 ปีที่แล้ว +1

    Silver button then now getting close to golden button
    Good luck

  • @sunlittle1837
    @sunlittle1837 2 ปีที่แล้ว

    Thank you for everything you do^^

  • @faizanqureshi3894
    @faizanqureshi3894 2 ปีที่แล้ว

    Ninja legend truly....

  • @ughsirius
    @ughsirius 3 ปีที่แล้ว

    Thank you soooooooooooo much Zach!!

  • @drsahiba8763
    @drsahiba8763 4 ปีที่แล้ว

    Your videos are like a dessert 😊💕

  • @margaritayenikieieva4850
    @margaritayenikieieva4850 3 ปีที่แล้ว +2

    Hi! thank you so much, its really helpfull for medstudents) However one thing Ive noticed in purine structure 2:42 is missed N in a circle :)

    • @tanapolyaowarat437
      @tanapolyaowarat437 3 ปีที่แล้ว +1

      And also missing the double bond in adenine

  • @Msjrdskdn
    @Msjrdskdn 3 ปีที่แล้ว

    Valid like salad bruh 🙏🏽 ninja nerd is the goat

  • @ilayerbey
    @ilayerbey ปีที่แล้ว

    Oh my… Guy who teaches biochem but looks like Noah Centino just CHANGED MY LIFE

  • @angelalourine1199
    @angelalourine1199 3 ปีที่แล้ว

    Saved my lifee..thanks

  • @pokurisai6244
    @pokurisai6244 3 หลายเดือนก่อน

    am bout to cry this gotta be the hardest topic in biochem

  • @priyankamohan4845
    @priyankamohan4845 3 ปีที่แล้ว

    Sir, u are awesome , sir please kindly make videos on ischemia reperfusion injury

  • @Black-mj3yz
    @Black-mj3yz 2 ปีที่แล้ว +1

    Perfect !

  • @retooluvyuhx5569
    @retooluvyuhx5569 3 ปีที่แล้ว

    Thank you so much! May God bless youuuuu

  • @bethyxx2177
    @bethyxx2177 หลายเดือนก่อน

    This was so helpful!!!! thank youuuu

  • @tqrr2308
    @tqrr2308 3 ปีที่แล้ว +1

    Thanks a lot 👏👏

  • @becherkapuka1149
    @becherkapuka1149 4 ปีที่แล้ว

    Thank you very much i really needed this metabolic pathway.

  • @zoricabarth6462
    @zoricabarth6462 4 ปีที่แล้ว

    Your handwriting got so much better over the years haha

  • @ahmanburrs3028
    @ahmanburrs3028 4 ปีที่แล้ว

    Thank you for sharing this information in your own fashion. Very cool and very good!

  • @DM-hu5vo
    @DM-hu5vo 3 ปีที่แล้ว

    ur the best, ty so much from Russia with love

  • @mldykes19
    @mldykes19 3 ปีที่แล้ว

    Thank you so much for breaking this down.

  • @sofeamaria5592
    @sofeamaria5592 3 ปีที่แล้ว

    tq. really help with my assignment

  • @philippbakayoko7352
    @philippbakayoko7352 4 หลายเดือนก่อน

    oh boy, this was heavy!

  • @saiteja6742
    @saiteja6742 4 ปีที่แล้ว +1

    Sir Do pharmacology on antimalaria, antihelminitics, antileprotic..

  • @adrienneuribe835
    @adrienneuribe835 3 ปีที่แล้ว

    Thankyou thankyou thankyou soo much ! I finally get it

  • @ML-ni1tk
    @ML-ni1tk 3 ปีที่แล้ว

    thankyou soooo much that you and your team putting to making these videos for us.They really help. ❤❤❤❤❤❤❤❤

  • @user-ys1fs6fd5l
    @user-ys1fs6fd5l 11 หลายเดือนก่อน

    such an amazing thing!!! hope you keep doing more amazing vdo soon.

  • @laaquino7846
    @laaquino7846 3 ปีที่แล้ว

    If i graduated one of my speech will be mentioning Ninja Nerd

  • @wardaqamar5969
    @wardaqamar5969 3 ปีที่แล้ว

    You're a gem🥺🥺🥰🥰

  • @leenkhaswanea3956
    @leenkhaswanea3956 2 ปีที่แล้ว

    Thank u for your amazing lecture