I just took your quiz and I've been dealing with chronic discomforts and pain with no answers for over 13 years. I scored almost all questions 😢. I'm in kenya, what tests do I ask my doctor for? Thank you so much for your help❤
I'm an hEDS patient, it seems to be something we live with, I've found a number of ways to avoid the Rx meds (I'm also allergic to a lot of drugs) as much as possible.
The medical system today is so bad that we all have to somehow become our own doctors. It's too much for me. Too many possible causes of every symptom. It's maddening.
I had to learn this on my own after a lifetime of severe daily anxiety and depression...I cut out food allergens, added a daily antihistamine and I've been miraculously cured for a year. It's incredible.
@user-sk2fw8jq3m zyrtec! But not just any zyrtec. I used the gel capsule because it does not contain lactose. All of the regular zyrtecs do. I have a bad histamine response to lactose. Not sure if you are in the USA but I specifically use the Walgreens brand of zyrtec. I tried to switch to the Walmart brand, and had an allergic reaction....the only difference in ingredients was that the Walmart brand contains BHA which is a nasty chemical.
@@notpanstarrsroblox16 Although Zyrtec blocks H1 and/or H2, it does not break down Histamine and that Histamine can then go on to fill your H3 and H4 receptors in the brain and nervous system, causing mental issues, as this video touched on. Be careful. Be educated. Histamine is used by the body to produce Chongroiten to help your joints function. Without histamine your body may start to break down eventually, especially if you exercise.
I have never heard of Excess Brain Histamine intolerance, Only familiar with the the word histamine when it comes to allergy relief. This is so interesting and informative. Thank You!
@@DrRichardHagmeyerdo you have a video on HOW: *Amino Acid Histidine* can support or heal *Hypochlorhydria* via supporting/as a precursor to the production of histamine in the stomach as part of the steps to produce stomach acid? I have Achlorhydria, so I am looking for anything to improve it...
@@1truthseeking8how do you say you have it. Asking because my son is suffering a logmt because of histamine and the doctors just dismiss it whenever i bring it up.
@@DrRichardHagmeyer Thank you. I am fully aware that it is not a quick fix. I personally use Toxaprevent to lesson my histamine bucket load. I thought perhaps you might have a separate video on the topic. I will check out your other comments, as you kindly suggested.
A lot of folks in the comments are asking what to do with excess histamine. Check if you are undermethylated and correct it via diet/supplementation. Proper methylation clears up excessive histamine from our bodies.
I’m allergic to everything and have been on a low histamine diet for months. The DOA has helped me a lot with the bloating on my low histamine diet. But no Drs around here know as much as Dr Hagmeyer
I’ve had an intense allergy season with this hectically blocked nose and itchy mouth/face/eyes for the last month and the allergy tablets weren’t working so yesterday I went to my doc for an allergy shot. So it’s something like cortisol steroids or something and lasts like 3 or 4 months. I used to have it often when I was a student because I was allergic to some grass or dust mite in my student town. Anyway I’ve always found that the day or two after the allergy shot I feel amazing. Like sluggish cognitive tempo and ADHD (AuDHD?) symptoms improve loads. Like sure it maybe keeps me awake a bit on the first night ruminating about exciting projects (I usually sleep like a baby even with mouth breathing). Hells I went for a walk and even my v02 max on my watch is 2 points higher. So yeah I’ve always figured there’s some link between allergies and cognition. Thanks for the vid!
i struggle with atrial fibrillation , palpitations, high and low blood pressure after eating histamine rich foods. i have been on low histamine diet for over a year and know which foods to avoid but still having at least two episodes a month and finding i react to new foods each month. dieticians have said its histamine intolerance but my doctor needs a proper diagnosis for sick leave as i cant work. so i was sent to immunologist. She laughed at me and said there is no such thing, it was a word bandied about back in the 80s and said i had no allergies. I said i know i have no allergies, its an intolerance , but she just went on saying she would prove i have no allergies and that its a heart problem , i should be with a cardiologist not immunologist.
I also have food intolerances and feel no One can help. All tests normal! Quit dairy, gluten, corn, grains. Did low FODMAP. Most carbs that are not meat or vegs give me rashes and can make me lethargic
The first allergist/immunologist my primary doctor sent me to was not on board with food intolerance/sensitivity and the 100 prick test on my back only returned one mild reaction. The subsequent doctor did a blood antigen test and a host of food and environmental tags popped up. I basically went to a high protein/paleo diet which helped tremendously. It takes a long time to detox, lower the hyperactive systems and heal. It's impossible to heal in a chronically stressed state. The sympathetic [fight or flight] dominant state, prevalent in modern societies, changes many chemical pathways to deal with the stress, real or perceived. Sleep, where cleaning and repair takes place, is hampered. Sleep, relaxation, rejuvenation, procreation happens in the parasympathetic portion/phase on the autonomous nervous system. Moreover, it appears that he 'blue zones' lead a more calm, low stress, life which contributes to their longer life span.
I focused on gut healing for 8 years and only got worse, costing me a fortune. After moving out of a moldy environment and 2 years of a nervous system rewiring program, I have been able to get my symptoms under control. If your limbic/nervous system is dis-regulated, no amount of gut healing will work.
Daily meditation to prime the brain to re-learn, then I use a training program. There are several, DNRS is prescribed by many doctors, Gupta Program is more thorough and what I use. They have a free trial so you can see how the program works, but you have to do it every day to see results. Not like taking a pill. But it works!
I had all of the symptoms of narcolepsy, they where sure i have it, my body go on full body paralysis, and sleep attack, all genes come back normal, then i had starting huge convulsions, ticks, they taught oh epilepsy, again all test come back normal..they gave me functional nevrological disorder, but gosh now that i am learning all of this, and having all of this symptoms i figure out it is histamin and mast cells activation..the first thing is to fix the leaky gut, and for that gaps diet is crutial, to start healing the gut wall properly!😊
@@stellaancimer8505 hope you get better. The @holes call everything “functional” that they can’t explain, meaning it’s all in your head, basically. And there is so very much they can’t explain, because they know so little.
@@stellaancimer8505 I’ve tried to reply to you 30+ times above, I’ll try here. Top recommendations are: hydrogen generator from promolife, use 2-5 hrs a day to get started. Keto-carnivore diet, no processed foods. Avoid supplements as much as possible, rely on red meat, cod liver oil. Take raw food based Vit C, liposomal glutathione and fulvic-humic minerals but stay away from other supps as much as possible. Oh, and lugol’s iodine, start with 1 drop a week and work up very slowly to 1 drop 2 days a week, etc., until 1-2 drops a day. That should take 6 months to work up. Infrared light panel is super helpful, 3 ft at least, use 2 x / day for 15 mins each. Either the hydrogen or infrared light will help you feel better w/in hrs or days, as far as energy, mood and mental clarity, if you use as described. Look for an interview by Thomas DeLauer on Fatty 15.
@@stellaancimer8505 I’ve tried to reply to you 30+ times above and I tried here too, but the platform keeps deleting them. I wish I could help. Blessings to you.
I had a terrible withdrawal for months from Cymbalta -- I've never felt so unhinged -- took Benadryl antihistamine and was instantly okay. It was a dramatic and instantaneous shift.
Wait a minute... I'm trying to taper off of cymbalta at the time of this comment. I take a little bead out about every week or two. I'm only down 6 little beads atm. I'd love to know more about your experience with this
@@patrickwright4070 Hi - I tapered as per doc's instructions but maybe the way you're doing it, it won't be so intense. My symptoms: like every nerve was exposed and buzzing, electrical brain zaps, deep depression, lightening anger (like seriously it should be a mitigating factor in violent crimes), crazy dreams and terrible sleeps...probably more but I've blocked it out. It went on for about 3 months before I tried an antihistamine. I guess some people are helped by this drug but it's awful to withdraw from. Best of luck - there are many, many people out there who have gone through this.
I am having serious issues right now with the brain part of this. I cannot control my body temperature regulation. I can’t remember words, and I have anxiety through the roof. I am also having all the gut related issues with very high BP and palpitations. I have had peripheral neuropathy for 12 years of unknown origin. When I went to the ER they acted like I had two heads. Where can you get help? My doctors don’t have a clue.
They have a clue! I have the same symptoms and more. Go research histamines produces in the body and the blockers and triggers for the release of this irritant. Ive learned so much about conditions today the cause, the treatments that don’t work and how Drs prescribed meds and tests to make money off of you . They want to keep you feeling sick to keep the healthcare system and machine well oiled! Up and running full steam to make corporate profits big, at our expense. Ive felt symptoms increasing for the past 8 yrs and they were trying to make me feel like I’m Crazy. And Im the opposite of a hypochondriac. So here I am thinking that Im done going begging for help. I’m the only person who can help me!
There’s alot we don’t know about HNMT and brain histamine- we know far more about DAO. HNMT influences so many areas of brain. www.drhagmeyer.com/genetics-of-histamine-intolerance/
Yes this what happens to many people, if you dont work with someone who looks at the BIG picture. Have you checked out some of my blogs on this topic? www.DrHagmeyercom
@@DrRichardHagmeyerSir, does it mean that - in general it's not a good idea that such people like us take anti-depressants instead of addressing the main problem with too high histamine levels in the brain?
The first allergist/immunologist my primary doctor sent me to was not on board with food intolerance/sensitivity and the 100 prick test on my back only returned one mild reaction. The subsequent doctor did a blood antigen test and a host of food and environmental tags popped up. I basically went to a high protein/paleo diet which helped tremendously. It takes a long time to detox, lower the hyperactive systems and heal. It's impossible to heal in a chronically stressed state. The sympathetic [fight or flight] dominant state, prevalent in modern societies, changes many chemical pathways to deal with the stress, real or perceived. Sleep, where cleaning and repair takes place, is hampered. Sleep, relaxation, rejuvenation, procreation happens in the parasympathetic portion/phase on the autonomous nervous system. Moreover, it appears that he 'blue zones' lead a more calm, low stress, life which contributes to their longer life span.
Thank you so much!!!!!!!!! I've been taking a prescription antihistamine for histamine intolerance, and I swear I couldn't connect all the dots no matter how much research I did about it didn't all fit. Now the sleep cycle, leptin and failure to lower sugar and weight loss all make sense. I have had the intuitive swing to stop taking the pills but I couldn't figure out why. Thank you. I'll check out the other videos.
Very well said about hnmt. I'm in various MTHFR groups in reddit and I've done a ton of research on hnmt/histamine and methylation. I suffer from various mutations that cause a very reduced methylation. This WILL 100% result in reduced hnmt function. Hnmt is the only thing that can break down/metabolise histamine in the brain. Moa-a enzyme further breakes down N-methylhistamine but its far less important than hnmt. Hnmt needs SAM-e as a co-factor to function. If your body's methylation is reduced then your SAM-e will be reduced as well. Resulting in an increase in brain histamine and all the issues that go along with having too much histamine in the brain. High histamine causes so many issues in the brain. It causes issues with the circadian rhythm. It triggers headaches via its actions on nmda receptors. It's involved in depression, anxiety, insomnia, sleep, Parkinsons.
@@maartje3262the medical medium recommends celery juice, this is high in oxalates, people with histamine issues may have oxalate issues as well due to gut health issues. I have issues with both and personally would not follow the medical medium’s advice.
I seem to have become sensitive to foods. So I have put it down to histamine intolerant. Now I have very itchy eyes which I thought possibly high pollen levels. My body feels swollen, especially my arms. Also joint pains when I have a trigger. Sometimes my body feels warm/hit from inside. Please help. I've been to a few physicians and not one has come up with this or even suspected this. I think I may be in menopause too. I will be 50 in January. I have a few friends my age that are experiencing food allergies too, that they previously never had. I have a lot of mucus too and am always coughing
Look into a carnivore diet. I’m on month 4 and 90% of my histamine reactions are gone. No more itchy throat, eyes, ears or skin. My skin rashes are gone too. Plus, I no longer have achy joints, nor brain fog. I feel terrific!
Thank you for this helpful video! I have MS and severe allergies, and have only recently been learning about the effects histamine has on these conditions.
My Doctor put me on Famotidine 20mg twice a day for my acid reflux. I believe Famotidine is a H2 blocker. Later my Doctor put me on Mirtazapine for anxiety. I believe Mirtazapine is a H1 blocker. I was taking 7.5 mg for 2 years . I quit the Mirtazapine 16 months ago and am still suffering with withdrawal symptoms. I then cut down the Famotidine to just 20mg once a day for about 6 months. I just cut the Famotidine down again to just 10mg once a day. My symptoms are all head related like headaches, ears ringing, brain fog. I was just wondering if the Famotidine is keeping me from healing from the Mirtazapine, since they are both histamine blockers.
Wow, mind blowing information! So enlightening! I always suspected there was a connection between too much histamine and symptoms of anxiety, ADHD, insomnia etc but this short video explained it so well!! The best and most succinct explanation I've come across so far. Thank you so much. So the big question is : How does one address the excess in the brain if DOA and antihistamines aren't the answer?? Are there supplements, medications, diets, exercise etc that could help?
@@minabish1783 I think you will like this pmc.ncbi.nlm.nih.gov/articles/PMC3016451/#:~:text=Strong%20and%20consistent%20evidence%20exist,1%20receptor%20antagonists%20promoted%20sleep.
So informative. Learning so much about this and this is yet another video that has helped me make connections. This won't be a popular statement, but coffee has played a huge part in this problem for me. Even though you didn't mention caffeine, it IS a drug and from what you're saying and the list of signs and symptoms of low dopamine, coffee has most definitely caused this in me. I've been saying that when I've been drinking coffee over a period of time, I get ADHD symptoms, can't focus, difficulty prioritizing, disorganized thinking. And then that makes me have low drive and motivation. When I stop the coffee, in about a week I'm ready to organize the stuff that got cluttered and disorganized while drinking coffee. I'm much more calm about life in general and my reactions to stressful stuff is less intense. Also coffee effects my digestion. I can't eat as much of a variety because I react to them with HI symptoms. but when I quit, that changes and my digestion gets better.
Hi Lisa Both MCAS and CIRS are very complex disorders that reach into many systems of body. Unfortunately, not something I can answer in a Format like this. I encourage you to reach out to my office to schedule a discovery call so we can discuss further.
I found Pepcid really helped my histamine. I take 10 mg in the evening ( makes me sleepy) Next day i have far less pain in my feet and much more energy 😮 I am thrilled. I feel do much better.
@@nancysmith-baker1813 It's an antacid pill. In USA it's over the counter. It has an anti inflammatory and anti Histamine effect. During COVID the Chinese shared that people in Pepcid survived early COVID and had better outcomes. COVID escalates your histamine through the roof. . I have been worse since having COVID two years ago. I feel Pepcid really helps me feel good 👍
I broke my neck last year in june , c2-c6. Fractured c3 c4and c5 removed replaced with titanium, i was paralyzed from elbows down for a while, they told my id never walk again , iv healed well , i have brown sequard syndrome but i can walk and im doing great all things considered, but i get truly horrible head aches occasionally, where i get intense pain behind my eyes, trust me i know pain and this is bad, but also get very hot and start sweating badly the only thing i can connect it to is allergies but iv never had allergies my whole life, im 23 and i spent the first 18 years of my life on a hay farm , everything that stops the headaches also treats allergies, bynadryl, caffine , ephedrine, Phenylephrine, even my adhd meds but i know adderal used to be a alergy med under the name bynzadryne , do you have any idea if this could be histamine related sorry for tge long comment im just hooing to get some information
Thank you for telling us what histamine is BUT you didn't tell us anything that would actually help us to lower our histamine or increase our histamine or what's causing the problems and what to stay away from.
This totally brings together my whole health picture. There’s no doubt it’s what has been going on with me my whole life. At first I had hope. But what you say at 11:20 completely deflated me all over again.
Great video thanks! so if i understand this right then i need another type of DAO enzyme that digest the excess histamin in the brain since im suffering from severe insomnia. is that correct ? If so where can i get HNMT and MAOB enzyme that you mention in the video and is there a supplement that contain all 3 of them, DAO, HNMT and MAOB ? Or should i try DAO enzyme first that taget the histamin in the gut and see if that reduce my insomnia?
Nutrient cofactors for HNMT include lcopper, iron, B vitamins, vitamin C, SAMe, magnesium, manganese, cobalt, zinc, and molybdenum. These are all needed as cofactors to allow MAO-A and MAO-B DAO abd HNMTto work. I would also recommend following low Histamine diet for 3 months to see if symptoms improve, then work on all things “filling up the bucket!”
I have had severe insomnia for the past three years since my diagnosis of Sibo. My histamine intolerance started after Sibo and has never gotten better with trying to heal my gut. I depend on a low histamine diet and DAO daily. If you have anymore information on how I can heal the histamine intolerance in my brain omg 😳 😢please share!
Why do you keep stating the problems related to histamine intolerance but offer no solutions! It's scarey to hear you say that histamine can cause brain dysfunction. Asking people to do a quiz suggests to me you are trying to recruit people as research guinea pigs to further your own career and youtube channel views m@@DrRichardHagmeyer
Hi ,. Me from India suffering with this since 3 years ., saw lot many videos , but , found right information only in this video .Thank you very much . Am expecting some more information /steps , how to come out on this particular issue .
I have Type 1 Narcolepsy and have been prescribed Pitolisant for the past 3 months. I still don't understand if the drug raises histamine levels or merely makes the brain more receptive to existing levels. I am anxious about the possible long-term effects of raised histamine. I feel like a Guinea pig. I had terrible bouts of HSP vasculitus in the past and am long-term depressed. I also read it may increase chance of developing Parkinson's which my Grandpa died with. Very nervous.
Very understandable. Not familiar enough with narcolepsy and medications prescribed to treat it. I would look into testing neurotransmitters and genetic SNPS as it relates to NT and methylation.
It’s not that simple. I see a lot of people asking that question. This is a very complex problem. Your treatment needs to be personalized to you. There are many root causes- you need to find out what’s YOUR root causes. Work with a certified functional medicine doctor.
Pulmonary Hypertension was suspected to be due to poor sleep as all other tests were negative. The cause could be Histamine intolerance as the symptoms match as described in the video. I suspect that high intake of chickpeas in breakfast over months led to higher histamine. The sleep quality improved with higher nutritive intake of banana, cur/yogurt which help better make the neurotransmitters. Thanks a ton for the missing link Dr Hagmeyer.
Very interesting talk. I was tested for allergies a year ago due to inflammation of the skin. Since I was a teenager I have suffered with stomach problems and sleep. I’m 65 years old and after a positive result of three chemical elements I now take cetirizine on a night and it has helped so much with sleep and stomach ache. I also have osteoarthritis and have noticed a slight reduction in joint pain too! Wish I had been tested years ago!
My Allergist said I was his Worse patient in 40 years and I still suffer!! I tried Steroids, shots, drops and never get relief! I discovered Histamines myself and I'm trying capsules to block as well as eliminate over making histamines. I cannot ever cheat by eating the wrong thing because the headache doesn't go away. Sometimes the histamine capsules help. I pray everyday for help! Your video was very interesting and informative. Benadryl and ibuprofen are bad for me but I sometimes get a lil relief.
This is so bloody interesting! It sounds a lot like my ADHD symptoms?! What if I actually don’t have ADHD and I actually have an imbalance or intolerance to histamine 😮
Testing for “histamine intolerance in brain” cant be done as far as I know. It’s also very difficult to test in blood. The most accepted way is through a questionnaire and through clinical symptoms presentation of the patient. There are tests available but for most part researchers have found that they are not very accurate and don’t correlate well. Treatment for histamine intolerance is a challenge and is discussed in some of my other videos.
@@vallang4832 very true but ingested foods have more to do with histamine and DAO enzyme in gut, for histamine issues in brain we’re talking about HNMT enzyme. Foods high in histamine have little to do with this HNMT. For patients who struggle with food and metal health it might be other biogenic amines in foods causing problems.
You are saying that with to little histamine you get tics and seizures..and sleepproblems, i have all these in pollenseason, but i thought it was because of to much histamine..??? How do i know? As soon as pollenseason starts i get these seizure type things, and poisened feeling….it is a very big problem..sometimes i get paralysed. It is very important to know if this really from to low histamine?
@@marleenvanwijngaarden2179 it’s impossible to say- different parts of the brain respond differently to histamine. Histamine in brain is incredibly complicated.
@@DrRichardHagmeyer I'm not a doctor, but is it possible that pollen season is causing a histamine response in the periphery leading to a decrease in brain histamine levels
@@marleenvanwijngaarden2179 it’s not possible to check amount of histamine in brain. 🧠 different parts of brain produce histamine and then to further complicate, histamine can act like a relay switch for other neurotransmitters. I’ll be shooting a video today that provides further insight on things to consider. Stay tuned.
I have found Quercetin helps to bring down the histamine when i am having an anaphylactic reaction but i had no idea about the levels in the brain and how they affect us!
Can high histamine cause blood clots or strokes? After i had cvd " pnamonia " in 2021. I had strokes, clots. Would react to everything i ate. My neck went partially paralyzed right after i ate leftover spaghtetti and dropped to my shoulder
This happened to me. Dx sibo after colon surgery. But my mental health spiraled uncontrollably. But I would never go the the psych ward bc they wouldn’t be able to accommodate my diet and I was afraid of being Dx eating disorder. Yes! It was histamine. And oxalates! Does he have an MTHFR variant?
@@ej1coupeguy629 I eat a very restrictive diet, did a somatic trauma healing course and started seeing a psych nurse who deals with nutrient deficiency replacement and I am finally able to reduce my anxiety meds to where I was before the surgery and sibo. After my kidney stone and Christmas I’ll see if I can go further.
@@babsskett2757 please look at other videos on this channel as well as my blog www.DrHagmeyer.com there’s a lot of information here and on website for you.
I DO respect an MD who is willing to have a patient attempt Alternative diet vs. straight to medication!! I would question those intolerant may have a genetic Polymorphism that would cause problems with that much protein (ie Methionine). These diets help many remedy their GI problems.
my previous rheumatologist put me on hydrocodone 3 to 4 times a day for itchy skin. I'm out. I have fibromyalgia and RA along with many symptoms of perimenpause but recently I've had worse symptoms. I wonder if it is kind of a withdrawal from running out of Hydroxyzine. I am really working hard to keep my mind busy because I itch all over very badly and I keep spacing out. Feels similar to a seizure but not exactly. I have a lot going on and now I don't know which doctor I should talk to
I live in the Netherlands and am 52 years old. I have an allergy for more than 20 years, but also sleeping problems at night and often extreme sleepiness during the day. September this year I went to Jakarta Indonesia, one of the most polluted cities in the world, and guess what, this whole month the allergy symptoms were gone. No burning eyes, no sneezing and runny nose, no itchy skin and I slept like a baby, despite the extreme noise of this city. All kind of things I thought of in the past - pollution, electro smog, cats - turned out to be not the problem. Is there a solution? (Other than moving to Indonesia)
Is there any supplements to raise low histamine? My histamine is low as well as norepinephrine and epinephrine and serotonin. I have sleep issues and reaction time very slow. Mood is low anxiety all day. Feeling like I can’t balance my body. Any advice?
Sir is there a time to take these supplements individually? Like histadine? Or how long too take it? With food or at night? Thanks for responding. Really appreciate it.
I never thought of histamines as the root cause of some symptoms. My reaction to certain foods, chemicals, aerosols involves head spins, negative mood, sleepiness. Until now I didn't know what was the exact cause and process. Thank you
@@wickyhaack5270 first test Breath test and test for leakygut. First stop with A1 milk and products and all gluten start eating real foods fres as possible if you can take have fruit eat is but as a snack 1/2 uur before or 3 hours after a meat and vegetable meal
@@DrRichardHagmeyer I know this is another topic , I have GERD, gastritis , Erosion Esophagus , Low Stomach Acid , can you give your opinion , how to manage Low Stomach Acid ? I know I can't be taking Apple Cider Vinegar because of Erosion Esophagus, it would burn the throat . Thank you very much. Debbie .
Thank you for the information, I appreciate it since knowledge is power, and health is precious. Some years ago, I developed hives and angioedema (swelling of hands and left arm) due to a high intake of raw honey (mixed with organic full-fat yoghurt) -- which had soothed me during a time of emotional stress. The high histamine level was probably the result of a severe copper deficiency because of the high intake of fructose day after day. The copper deficiency might have caused a low level of the DAO enzyme. Unfortunately, I can't remember how the high histamine level affected my brain.
Checkout some of the articles on my website about how to support DAO enzyme. It’s on my website (www.DrHagmeyer.com) under blogs or health articles! It’s just what you’re looking for!
Thank you. This was very informative. I know I have challenges with histamine and possibly MCAS. I recently started a carnivore diet and seen improvements and also now I take Beef Kidney for the DAO. My main challenge remains flushes once in a while. Also at night, if our cat wakes me, I will flush and it will take 15 minutes to cool back down. I get pretty good itching on the front of my left shoulder and this usually has one tiny pin prick sore in the middle. I do not get hives unless you can get a single hive or maybe two close together. They are not bumps. I am improving, yet still puzzled.
I suggest you work with a certified functional medicine doctor. There is so much to histamine intolerance and MCAS. Most people are making themselves sicker!
You sure can! Their are 4 main Histamine receptors. H1,2,3,4. Itching/hives is associated with the H1 receptor. H2,3,4 are heart, neurological tissues, gut, lungs,
I have a slightly related question. Haven't noticed any of brain symptoms apart from restless mind. However, I did develop an alergy to milk 10 years ago, which is always present, as milk is everywhere and I never fully avoided it. I always have red spots on my body that migrate throughout months across different places on my skin. If it gets too difficult, I use mometason creams etс. How bad is it for me to have constant inflammation like this and is it possiblw to cure this allergy by obtaining from allergen for some time?
Can histamine intolerance cause brain lesions, hypertension, and a stroke? Doctors at the ER couldn’t figure out the lesion’s in my brain, and they also found a 1 inch hiatal hernia. I don’t know how to resolve this, but I’m very scared because my blood pressure can’t be controlled even with medication. I also have high amounts of Candida and anxiety.
Hello mr. Richard am suffering from this kind of problem you pointed in your video, i have done of course of lot's of medicine past 6 months 😢, but after medicine over problem is there as it was, .i have suffering symptoms like dry and itchy throat with fever like feeling in throat scratchy throat, fatigue muscles pain in whole body difficulty in rest also in sleeping, my doc proscribed me levocitizen & dihydrochloride 5mg that's help me temporary. 😢 please help me .
My odor causes others to have allergic symptoms like sneezing, coughing, and runny noses. Could this be related to the release of excessive histamine from my skin? I also have lesions in my brain, so I’m wondering if there might be a connection.
For a decade I googled “what medication to take for flashpoint rage” Could have saved some of my relationships and restored massive amounts of my mental peace and productivity if google had sooner given the answer: loratadine. And yes, I’d been a psych patient for years. Anxiety, low key mania, delusions, compulsions/perseveration/distortions, distrust and paranoia, ideas of reference, explosive self harm, inability to concentrate or learn easily, chaotic, disorganised, socially impaired. The gammut of medications, of which ONLY mirtazipine, olanzapine, and to a much lesser extent quetiapine actually treated my symptoms. But brought many side effects and issues both short and longer term. OTC godsend thank you loratadine does it so much better than the “psych” meds.
So what is the solution to this? I keep thiking Ive lost my mind and its completely hopeless. It really feels like Im not all there mentally and I get comments from people at work 😩😩😩
thinking of trying to help after dinner MSG headaches, by taking some anti-histamine OTC to reduce symptoms. I already take caffiene to counter the sleepiness, but that too can increase histamines? yes?
@@farhanbaig678 please look at other videos on this channel as well as my blog www.DrHagmeyer.com there’s a lot of information here and on website for you.
@@GVChristian DAO is an enzyme produced in the gut and works on histamine produced by bacteria as well as histamine ingested from Food. Histamine in the brain is broken down by another enzyme HNMT. If you visit my website lots of articles on this! www.DrHagmeyer.com look under health articles or blogs
Im carnivore and loving it recently started histamine problems but im starting to think weening myself if cymbalta could be causing it by the sound of this video?!
My son has generalized epilepsy (severe) we were told benedryl and all antihistamines cause seizures. We took him off of it, he has awful allergies so he takes steroid nasal spray. Is there a test for histamine levels and mast cell levels?
I’m struggling with constant hunger after taking fexofenadine for 5 months. I stopped it two months ago but the hunger isn’t going away. I don’t know what to do anymore.
@@RicardodelaFuente-t3r please look at other videos on this channel as well as my blog www.DrHagmeyer.com there’s a lot of information here and on website for you.
lower the amino acid histidine which turns into histamine. lower protein intake dramatically lowers histamine.......but it takes time. Eat a small amount of meat......no need to be unnecessarily bulked up.
So how do you treat excess histamine in the brain and gut? You mention H blockers aren't enough and a low histamine diet isn't sustainable... So what do you do? You give no answer to this.
Fasting long enough to bring on autophagy is the best and really, the only way to repair the gut. Dr Paul Anderson has a video about this; he recommends at least a 5-day fast, water only.
![ลองสุ่มไอโฟน 990 โกงมั้ย? [ โกงมั้ยครับ ep.101 ] | DOM](http://i.ytimg.com/vi/bfsWe0j492k/mqdefault.jpg)
You can find the MCAS/histamine quiz here
drhagmeyer.com/histamine-intolerance-quiz/
I just took your quiz and I've been dealing with chronic discomforts and pain with no answers for over 13 years. I scored almost all questions 😢.
I'm in kenya, what tests do I ask my doctor for? Thank you so much for your help❤
I'm an hEDS patient, it seems to be something we live with, I've found a number of ways to avoid the Rx meds (I'm also allergic to a lot of drugs) as much as possible.
Wow. My own feeling of being braindammaged of leaky gut is real...and the big histamine reaktions. Thank you for clarifying all these symptoms 🙏.
🙏 🙏 🙏
@@Andrea-u2f Yes hearing about it was a great relief for me.
The medical system today is so bad that we all have to somehow become our own doctors. It's too much for me. Too many possible causes of every symptom. It's maddening.
True! We need to self advocate but I suggest you work with a certified functional medicine doctor. It’s very easy to make yourself sicker!
Tell me about it. Been my life for the past 4 years
I had to learn this on my own after a lifetime of severe daily anxiety and depression...I cut out food allergens, added a daily antihistamine and I've been miraculously cured for a year. It's incredible.
Please, what Antihistamine did you use ??
@user-sk2fw8jq3m zyrtec! But not just any zyrtec. I used the gel capsule because it does not contain lactose. All of the regular zyrtecs do. I have a bad histamine response to lactose. Not sure if you are in the USA but I specifically use the Walgreens brand of zyrtec. I tried to switch to the Walmart brand, and had an allergic reaction....the only difference in ingredients was that the Walmart brand contains BHA which is a nasty chemical.
@@notpanstarrsroblox16 Thank you so much!! 🙏 I’ll try to get this locally.
@@notpanstarrsroblox16 Although Zyrtec blocks H1 and/or H2, it does not break down Histamine and that Histamine can then go on to fill your H3 and H4 receptors in the brain and nervous system, causing mental issues, as this video touched on. Be careful. Be educated.
Histamine is used by the body to produce Chongroiten to help your joints function. Without histamine your body may start to break down eventually, especially if you exercise.
I'm on board here. Basically I am allergic to being human.
That's me too😂
Or just allergic to myself.😱
Thats it!!!!😅
You are not alone. It also can lead to being allergice to certain other humans.
@@pdz-pk4od yes, that too😊
I have never heard of Excess Brain Histamine intolerance, Only familiar with the the word histamine when it comes to allergy relief. This is so interesting and informative. Thank You!
Thank you for this amazing video!! You are a godsend!
You're so welcome!
I benefited a lot from this lecture, even though I do not know English, but the TH-cam translator did the job.
This is the most informative discussion on histamine ever. Thank you for this review!
Glad it was helpful!
@@DrRichardHagmeyerdo you have a video on HOW: *Amino Acid Histidine* can support or heal *Hypochlorhydria* via supporting/as a precursor to the production of histamine in the stomach as part of the steps to produce stomach acid?
I have Achlorhydria, so I am looking for anything to improve it...
@@1truthseeking8 great suggestion!
@@1truthseeking8how do you say you have it. Asking because my son is suffering a logmt because of histamine and the doctors just dismiss it whenever i bring it up.
Thanks, but what is the solution? How do we balance histamine in the brain? Did I miss that part?
Read my previous comments. This is not going to be fixed with a single supplement or a TH-cam video. 🙁
@@DrRichardHagmeyer Thank you. I am fully aware that it is not a quick fix. I personally use Toxaprevent to lesson my histamine bucket load. I thought perhaps you might have a separate video on the topic. I will check out your other comments, as you kindly suggested.
A lot of folks in the comments are asking what to do with excess histamine. Check if you are undermethylated and correct it via diet/supplementation. Proper methylation clears up excessive histamine from our bodies.
It’s not that simple when it comes to HNMT and histaminergic neurons in brain.
@@DrRichardHagmeyerme and my son both suffer with this, do you have any suggestions on what will help?
@@carrierogers7475 hi there, there are several videos on my channel about histamine and even more articles on my website- www.DrHagmeyer.com
Stay tuned. I’ve got a few videos ready to drop on this topic!
@@carrierogers7475 I’ve got a few videos that will be posted shortly that you might be interested in. Stay tuned!
MRNA VACCINE BLOCKS THE ACE 2 Inhibitor it is in the Pfizer doc what does that mean?
People are becoming very ill.
😮Oh no! I took it and boosters. No wonder I am having allergic episodes and bad fibromyalgia
Besides serious health issues, many people are having horrible psychological problems. It’s bad news all around.
I’m allergic to everything and have been on a low histamine diet for months. The DOA has helped me a lot with the bloating on my low histamine diet. But no Drs around here know as much as Dr Hagmeyer
Get checked for SIBO
I’ve had an intense allergy season with this hectically blocked nose and itchy mouth/face/eyes for the last month and the allergy tablets weren’t working so yesterday I went to my doc for an allergy shot. So it’s something like cortisol steroids or something and lasts like 3 or 4 months. I used to have it often when I was a student because I was allergic to some grass or dust mite in my student town.
Anyway I’ve always found that the day or two after the allergy shot I feel amazing. Like sluggish cognitive tempo and ADHD (AuDHD?) symptoms improve loads. Like sure it maybe keeps me awake a bit on the first night ruminating about exciting projects (I usually sleep like a baby even with mouth breathing). Hells I went for a walk and even my v02 max on my watch is 2 points higher.
So yeah I’ve always figured there’s some link between allergies and cognition. Thanks for the vid!
My pleasure!
Thanks for educating me on the effect of histamine on brain. Now, what can you use in place of histamine if you have allergy problems?
Here’s some suggestions
th-cam.com/video/Yc7AdvonWQU/w-d-xo.htmlsi=QODn2FxJ5aV85L1K
i struggle with atrial fibrillation , palpitations, high and low blood pressure after eating histamine rich foods. i have been on low histamine diet for over a year and know which foods to avoid but still having at least two episodes a month and finding i react to new foods each month. dieticians have said its histamine intolerance but my doctor needs a proper diagnosis for sick leave as i cant work. so i was sent to immunologist. She laughed at me and said there is no such thing, it was a word bandied about back in the 80s and said i had no allergies. I said i know i have no allergies, its an intolerance , but she just went on saying she would prove i have no allergies and that its a heart problem , i should be with a cardiologist not immunologist.
Get a sleep apnoea test for your afib
@@susanmcglade3295 always leave a doctor who doesn’t take you seriously
I also have food intolerances and feel no
One can help. All tests normal! Quit dairy, gluten, corn, grains. Did low FODMAP. Most carbs that are not meat or vegs give me rashes and can make me lethargic
The first allergist/immunologist my primary doctor sent me to was not on board with food intolerance/sensitivity and the 100 prick test on my back only returned one mild reaction. The subsequent doctor did a blood antigen test and a host of food and environmental tags popped up. I basically went to a high protein/paleo diet which helped tremendously. It takes a long time to detox, lower the hyperactive systems and heal. It's impossible to heal in a chronically stressed state. The sympathetic [fight or flight] dominant state, prevalent in modern societies, changes many chemical pathways to deal with the stress, real or perceived. Sleep, where cleaning and repair takes place, is hampered. Sleep, relaxation, rejuvenation, procreation happens in the parasympathetic portion/phase on the autonomous nervous system. Moreover, it appears that he 'blue zones' lead a more calm, low stress, life which contributes to their longer life span.
It all starts in the gut. Fix your gut. That's where to start.
I focused on gut healing for 8 years and only got worse, costing me a fortune. After moving out of a moldy environment and 2 years of a nervous system rewiring program, I have been able to get my symptoms under control. If your limbic/nervous system is dis-regulated, no amount of gut healing will work.
@@bc5810 I will have to look into that. Thanks
@@bc5810 nervous system rewiring program..whats that?
@@bc5810how do you rewire your nervous system?
Daily meditation to prime the brain to re-learn, then I use a training program. There are several, DNRS is prescribed by many doctors, Gupta Program is more thorough and what I use. They have a free trial so you can see how the program works, but you have to do it every day to see results. Not like taking a pill. But it works!
I had all of the symptoms of narcolepsy, they where sure i have it, my body go on full body paralysis, and sleep attack, all genes come back normal, then i had starting huge convulsions, ticks, they taught oh epilepsy, again all test come back normal..they gave me functional nevrological disorder, but gosh now that i am learning all of this, and having all of this symptoms i figure out it is histamin and mast cells activation..the first thing is to fix the leaky gut, and for that gaps diet is crutial, to start healing the gut wall properly!😊
@@stellaancimer8505 hope you get better. The @holes call everything “functional” that they can’t explain, meaning it’s all in your head, basically. And there is so very much they can’t explain, because they know so little.
@@stellaancimer8505 I’ve tried to reply to you 30+ times above, I’ll try here. Top recommendations are: hydrogen generator from promolife, use 2-5 hrs a day to get started. Keto-carnivore diet, no processed foods. Avoid supplements as much as possible, rely on red meat, cod liver oil. Take raw food based Vit C, liposomal glutathione and fulvic-humic minerals but stay away from other supps as much as possible. Oh, and lugol’s iodine, start with 1 drop a week and work up very slowly to 1 drop 2 days a week, etc., until 1-2 drops a day. That should take 6 months to work up. Infrared light panel is super helpful, 3 ft at least, use 2 x / day for 15 mins each. Either the hydrogen or infrared light will help you feel better w/in hrs or days, as far as energy, mood and mental clarity, if you use as described. Look for an interview by Thomas DeLauer on Fatty 15.
@@stellaancimer8505 I’ve tried to reply to you 30+ times above and I tried here too, but the platform keeps deleting them. I wish I could help. Blessings to you.
@@ava.artemis gosh..:( Just tell me did you have similar issue? Blessing to you too
I had a terrible withdrawal for months from Cymbalta -- I've never felt so unhinged -- took Benadryl antihistamine and was instantly okay. It was a dramatic and instantaneous shift.
Wait a minute...
I'm trying to taper off of cymbalta at the time of this comment. I take a little bead out about every week or two.
I'm only down 6 little beads atm.
I'd love to know more about your experience with this
@@patrickwright4070 Hi - I tapered as per doc's instructions but maybe the way you're doing it, it won't be so intense. My symptoms: like every nerve was exposed and buzzing, electrical brain zaps, deep depression, lightening anger (like seriously it should be a mitigating factor in violent crimes), crazy dreams and terrible sleeps...probably more but I've blocked it out. It went on for about 3 months before I tried an antihistamine. I guess some people are helped by this drug but it's awful to withdraw from. Best of luck - there are many, many people out there who have gone through this.
I am having serious issues right now with the brain part of this. I cannot control my body temperature regulation. I can’t remember words, and I have anxiety through the roof. I am also having all the gut related issues with very high BP and palpitations. I have had peripheral neuropathy for 12 years of unknown origin. When I went to the ER they acted like I had two heads. Where can you get help? My doctors don’t have a clue.
They have a clue! I have the same symptoms and more. Go research histamines produces in the body and the blockers and triggers for the release of this irritant.
Ive learned so much about conditions today the cause, the treatments that don’t work and how Drs prescribed meds and tests to make money off of you . They want to keep you feeling sick to keep the healthcare system and machine well oiled! Up and running full steam to make corporate profits big, at our expense. Ive felt symptoms increasing for the past 8 yrs and they were trying to make me feel like I’m
Crazy. And Im the opposite of a hypochondriac. So here I am thinking that Im done going begging for help. I’m the only person who can help me!
Here’s an article you might find interesting
www.drhagmeyer.com/genetics-of-histamine-intolerance/
There’s alot we don’t know about HNMT and brain histamine- we know far more about DAO. HNMT influences so many areas of brain.
www.drhagmeyer.com/genetics-of-histamine-intolerance/
@@DrRichardHagmeyer Thank you so much for your kind response. I will definitely read the article.
@@andsoitgoes1142 my pleasure
Nueropsychiatric symptoms are life destroying
Yes this what happens to many people, if you dont work with someone who looks at the BIG picture. Have you checked out some of my blogs on this topic? www.DrHagmeyercom
@@DrRichardHagmeyer I will search for them… Im using high dose oral progesterone at this point xxx
@@DrRichardHagmeyerSir, does it mean that - in general it's not a good idea that such people like us take anti-depressants instead of addressing the main problem with too high histamine levels in the brain?
The first allergist/immunologist my primary doctor sent me to was not on board with food intolerance/sensitivity and the 100 prick test on my back only returned one mild reaction. The subsequent doctor did a blood antigen test and a host of food and environmental tags popped up. I basically went to a high protein/paleo diet which helped tremendously. It takes a long time to detox, lower the hyperactive systems and heal. It's impossible to heal in a chronically stressed state. The sympathetic [fight or flight] dominant state, prevalent in modern societies, changes many chemical pathways to deal with the stress, real or perceived. Sleep, where cleaning and repair takes place, is hampered. Sleep, relaxation, rejuvenation, procreation happens in the parasympathetic portion/phase on the autonomous nervous system. Moreover, it appears that he 'blue zones' lead a more calm, low stress, life which contributes to their longer life span.
Thank you so much!!!!!!!!! I've been taking a prescription antihistamine for histamine intolerance, and I swear I couldn't connect all the dots no matter how much research I did about it didn't all fit. Now the sleep cycle, leptin and failure to lower sugar and weight loss all make sense. I have had the intuitive swing to stop taking the pills but I couldn't figure out why. Thank you. I'll check out the other videos.
Glad it helped pull some of the pieces together for you!
How do I get excess histamine out of my brain and my body ?
Thank you for this video. So what to do? What would you recommend?
I recommend you work with a certified functional medicine doctor
Very well said about hnmt. I'm in various MTHFR groups in reddit and I've done a ton of research on hnmt/histamine and methylation. I suffer from various mutations that cause a very reduced methylation. This WILL 100% result in reduced hnmt function.
Hnmt is the only thing that can break down/metabolise histamine in the brain. Moa-a enzyme further breakes down N-methylhistamine but its far less important than hnmt. Hnmt needs SAM-e as a co-factor to function. If your body's methylation is reduced then your SAM-e will be reduced as well. Resulting in an increase in brain histamine and all the issues that go along with having too much histamine in the brain.
High histamine causes so many issues in the brain. It causes issues with the circadian rhythm. It triggers headaches via its actions on nmda receptors. It's involved in depression, anxiety, insomnia, sleep, Parkinsons.
What do yoi do and what do you think of medical medium and his approach on this
What do I do then ):
So can you just take a supplement for this? And a low histamine diet?
we need answers
@@maartje3262the medical medium recommends celery juice, this is high in oxalates, people with histamine issues may have oxalate issues as well due to gut health issues. I have issues with both and personally would not follow the medical medium’s advice.
What local doctor would I go to to treat this? Thanks
I seem to have become sensitive to foods. So I have put it down to histamine intolerant. Now I have very itchy eyes which I thought possibly high pollen levels. My body feels swollen, especially my arms. Also joint pains when I have a trigger. Sometimes my body feels warm/hit from inside.
Please help. I've been to a few physicians and not one has come up with this or even suspected this. I think I may be in menopause too. I will be 50 in January. I have a few friends my age that are experiencing food allergies too, that they previously never had. I have a lot of mucus too and am always coughing
Have you taken the Histsmime/MCAS Quiz?
drhagmeyer.com/histamine-intolerance-quiz/
@@DrRichardHagmeyerhave you considered oxalate overload could be the problem?
I totally understand where you’re at. Most MDs are clueless. I’m so discouraged.
Look into a carnivore diet. I’m on month 4 and 90% of my histamine reactions are gone. No more itchy throat, eyes, ears or skin. My skin rashes are gone too. Plus, I no longer have achy joints, nor brain fog. I feel terrific!
@@Dfwade please look at other videos on this channel as well as my blog www.DrHagmeyer.com
there’s a lot of information here and on website for you.
Thank you for this helpful video! I have MS and severe allergies, and have only recently been learning about the effects histamine has on these conditions.
My Doctor put me on Famotidine 20mg twice a day for my acid reflux. I believe Famotidine is a H2 blocker. Later my Doctor put me on Mirtazapine for anxiety. I believe Mirtazapine is a H1 blocker. I was taking 7.5 mg for 2 years . I quit the Mirtazapine 16 months ago and am still suffering with withdrawal symptoms. I then cut down the Famotidine to just 20mg once a day for about 6 months. I just cut the Famotidine down again to just 10mg once a day. My symptoms are all head related like headaches, ears ringing, brain fog. I was just wondering if the Famotidine is keeping me from healing from the Mirtazapine, since they are both histamine blockers.
So how do you balance high/low brain histamine?
HNMT enzyme support DAO
Wow, mind blowing information! So enlightening! I always suspected there was a connection between too much histamine and symptoms of anxiety, ADHD, insomnia etc but this short video explained it so well!! The best and most succinct explanation I've come across so far. Thank you so much. So the big question is : How does one address the excess in the brain if DOA and antihistamines aren't the answer?? Are there supplements, medications, diets, exercise etc that could help?
DAO😅 DOA is another thing entirely
@@ev3332 Actually, DOA cures everything
@@ev3332 🤣
How come? Doesn't h1 regilates wakefulness? How does it cause sleeping disorders?
@@minabish1783 I think you will like this
pmc.ncbi.nlm.nih.gov/articles/PMC3016451/#:~:text=Strong%20and%20consistent%20evidence%20exist,1%20receptor%20antagonists%20promoted%20sleep.
So informative. Learning so much about this and this is yet another video that has helped me make connections. This won't be a popular statement, but coffee has played a huge part in this problem for me. Even though you didn't mention caffeine, it IS a drug and from what you're saying and the list of signs and symptoms of low dopamine, coffee has most definitely caused this in me. I've been saying that when I've been drinking coffee over a period of time, I get ADHD symptoms, can't focus, difficulty prioritizing, disorganized thinking. And then that makes me have low drive and motivation.
When I stop the coffee, in about a week I'm ready to organize the stuff that got cluttered and disorganized while drinking coffee. I'm much more calm about life in general and my reactions to stressful stuff is less intense. Also coffee effects my digestion. I can't eat as much of a variety because I react to them with HI symptoms. but when I quit, that changes and my digestion gets better.
What is the treatment for SIRS related to MCAS or just histamine intolerance?
Hi Lisa
Both MCAS and CIRS are very complex disorders that reach into many systems of body. Unfortunately, not something I can answer in a Format like this. I encourage you to reach out to my office to schedule a discovery call so we can discuss further.
I found Pepcid really helped my histamine. I take 10 mg in the evening ( makes me sleepy) Next day i have far less pain in my feet and much more energy 😮 I am thrilled. I feel do much better.
Wasn’t Pepcid linked to cancer recently? Look into this before continuing to take it.
Hi , what is pepcid thankyou .
@@nancysmith-baker1813 It's an antacid pill. In USA it's over the counter. It has an anti inflammatory and anti Histamine effect. During COVID the Chinese shared that people in Pepcid survived early COVID and had better outcomes. COVID escalates your histamine through the roof. . I have been worse since having COVID two years ago. I feel Pepcid really helps me feel good 👍
@@01maggie thankyou ill try it .
@@01maggie I take DOA got it at a health food store and it works . I'll try pepcid too .
Very interesting! I did not realize histamine was so complicated.
I broke my neck last year in june , c2-c6. Fractured c3 c4and c5 removed replaced with titanium, i was paralyzed from elbows down for a while, they told my id never walk again , iv healed well , i have brown sequard syndrome but i can walk and im doing great all things considered, but i get truly horrible head aches occasionally, where i get intense pain behind my eyes, trust me i know pain and this is bad, but also get very hot and start sweating badly the only thing i can connect it to is allergies but iv never had allergies my whole life, im 23 and i spent the first 18 years of my life on a hay farm , everything that stops the headaches also treats allergies, bynadryl, caffine , ephedrine, Phenylephrine, even my adhd meds but i know adderal used to be a alergy med under the name bynzadryne , do you have any idea if this could be histamine related sorry for tge long comment im just hooing to get some information
have you ever heard of the late dr john lee? (hormones)
my symptoms from hormones
Thank you for telling us what histamine is BUT you didn't tell us anything that would actually help us to lower our histamine or increase our histamine or what's causing the problems and what to stay away from.
Thanks for your comment. Please check out some of my other videos that touch on this topic.
Thyme is a natural way to reduce the Histamine
Will you kindly explain how to use thyme to reduce histamine.
This totally brings together my whole health picture. There’s no doubt it’s what has been going on with me my whole life. At first I had hope. But what you say at 11:20 completely deflated me all over again.
@@jochildress5003 so glad it helps
Great video thanks! so if i understand this right then i need another type of DAO enzyme that digest the excess histamin in the brain since im suffering from severe insomnia. is that correct ?
If so where can i get HNMT and MAOB enzyme that you mention in the video and is there a supplement that contain all 3 of them, DAO, HNMT and MAOB ?
Or should i try DAO enzyme first that taget the histamin in the gut and see if that reduce my insomnia?
Nutrient cofactors for HNMT include lcopper, iron, B vitamins, vitamin C, SAMe, magnesium, manganese, cobalt, zinc, and molybdenum. These are all needed as cofactors to allow MAO-A and MAO-B DAO abd HNMTto work.
I would also recommend following low Histamine diet for 3 months to see if symptoms improve, then work on all things “filling up the bucket!”
I have had severe insomnia for the past three years since my diagnosis of Sibo. My histamine intolerance started after Sibo and has never gotten better with trying to heal my gut. I depend on a low histamine diet and DAO daily.
If you have anymore information on how I can heal the histamine intolerance in my brain omg 😳 😢please share!
Watch the video to the end. Following a low histamine diet long term is not only not sustainable but it’s next to impossible. It doesn’ fix problem.
Why do you keep stating the problems related to histamine intolerance but offer no solutions! It's scarey to hear you say that histamine can cause brain dysfunction. Asking people to do a quiz suggests to me you are trying to recruit people as research guinea pigs to further your own career and youtube channel views m@@DrRichardHagmeyer
Hi ,. Me from India suffering with this since 3 years ., saw lot many videos , but , found right information only in this video .Thank you very much . Am expecting some more information /steps , how to come out on this particular issue .
I have Type 1 Narcolepsy and have been prescribed Pitolisant for the past 3 months. I still don't understand if the drug raises histamine levels or merely makes the brain more receptive to existing levels. I am anxious about the possible long-term effects of raised histamine. I feel like a Guinea pig. I had terrible bouts of HSP vasculitus in the past and am long-term depressed. I also read it may increase chance of developing Parkinson's which my Grandpa died with. Very nervous.
Very understandable. Not familiar enough with narcolepsy and medications prescribed to treat it.
I would look into testing neurotransmitters and genetic SNPS as it relates to NT and methylation.
Can i Ask you how test the neurotransmiter?@@DrRichardHagmeyer
Flush niacin is what helps me with my histamine issues, so just trowing it out there.
Now that’s interesting- Niacin can
Cause more histamine release.
How do we get tested to see what the problem is?
Very interesting, and sadly not easy to detect for as common as it it.
Yes that’s the problem! Histamine in brain is not the same as histamine from diet.
@@DrRichardHagmeyerhow do we address the histamine in the brain?? If not by antihistamines then what’s available to address this?
So whàt should we take and how much daily?
It’s not that simple. I see a lot of people asking that question. This is a very complex problem. Your treatment needs to be personalized to you. There are many root causes- you need to find out what’s YOUR root causes. Work with a certified functional medicine doctor.
Pulmonary Hypertension was suspected to be due to poor sleep as all other tests were negative. The cause could be Histamine intolerance as the symptoms match as described in the video. I suspect that high intake of chickpeas in breakfast over months led to higher histamine. The sleep quality improved with higher nutritive intake of banana, cur/yogurt which help better make the neurotransmitters. Thanks a ton for the missing link Dr Hagmeyer.
So what do we do? Where to start.
Very interesting talk. I was tested for allergies a year ago due to inflammation of the skin. Since I was a teenager I have suffered with stomach problems and sleep. I’m 65 years old and after a positive result of three chemical elements I now take cetirizine on a night and it has helped so much with sleep and stomach ache. I also have osteoarthritis and have noticed a slight reduction in joint pain too! Wish I had been tested years ago!
Thanks for sharing!
My Allergist said I was his Worse patient in 40 years and I still suffer!! I tried Steroids, shots, drops and never get relief! I discovered Histamines myself and I'm trying capsules to block as well as eliminate over making histamines. I cannot ever cheat by eating the wrong thing because the headache doesn't go away. Sometimes the histamine capsules help. I pray everyday for help! Your video was very interesting and informative. Benadryl and ibuprofen are bad for me but I sometimes get a lil relief.
This is so bloody interesting! It sounds a lot like my ADHD symptoms?! What if I actually don’t have ADHD and I actually have an imbalance or intolerance to histamine 😮
How can you be tested for histamine levels? I have MS and heard you reference that
I think
This will answer your questions. th-cam.com/video/x2x15qaan1Q/w-d-xo.htmlsi=9OFuQ0GbSZCz98I0
Very helpful ...thank you...your video confirms that my nontraditional methods for homeschooling are okay too...I love gameschooling too
Homeschooling is the best! We homeschooled up till 6th grade it was amazing times! Wouldn’t have traded it for the world!
Could this be a factor in vision snow syndrome and tinnitus
Perhaps- but not sure- many things to consider
I have both and I think so
How u treat it? How u diagnose it? Clinical? Because many other conditions have same sign and symptoms.
Testing for “histamine intolerance in brain” cant be done as far as I know. It’s also very difficult to test in blood. The most accepted way is through a questionnaire and through clinical symptoms presentation of the patient. There are tests available but for most part researchers have found that they are not very accurate and don’t correlate well. Treatment for histamine intolerance is a challenge and is discussed in some of my other videos.
@@DrRichardHagmeyerwhat do you think of medical medium and his approach
Some foods have more histamines than other foods. I am histamine intolerant. Even some left over foods will have risen histamines.
@@vallang4832 very true but ingested foods have more to do with histamine and DAO enzyme in gut, for histamine issues in brain we’re talking about HNMT enzyme. Foods high in histamine have little to do with this HNMT.
For patients who struggle with food and metal health it might be other biogenic amines in foods causing problems.
So how do you regulate it?
I sugest to heal the gut, i start with gaps diet 😊
You are saying that with to little histamine you get tics and seizures..and sleepproblems, i have all these in pollenseason, but i thought it was because of to much histamine..??? How do i know? As soon as pollenseason starts i get these seizure type things, and poisened feeling….it is a very big problem..sometimes i get paralysed. It is very important to know if this really from to low histamine?
@@marleenvanwijngaarden2179 it’s impossible to say- different parts of the brain respond differently to histamine. Histamine in brain is incredibly complicated.
@@DrRichardHagmeyer I'm not a doctor, but is it possible that pollen season is causing a histamine response in the periphery leading to a decrease in brain histamine levels
@@marleenvanwijngaarden2179 it’s not possible to check amount of histamine in brain. 🧠 different parts of brain produce histamine and then to further complicate, histamine can act like a relay switch for other neurotransmitters. I’ll be shooting a video today that provides further insight on things to consider. Stay tuned.
@@drakeweddner it is possible that histamine in the gut is contributing to problems in brain as well. Leaky gut leaky brain. 🧠
I have found Quercetin helps to bring down the histamine when i am having an anaphylactic reaction but i had no idea about the levels in the brain and how they affect us!
Can high histamine cause blood clots or strokes? After i had cvd " pnamonia " in 2021. I had strokes, clots. Would react to everything i ate. My neck went partially paralyzed right after i ate leftover spaghtetti and dropped to my shoulder
Strokes after getting a jab/ vax is normal these days. Serrapeptase or Natokinase could help.
@@mkykta9140 i didnt get the jab however this all happened within 3 days of being close with someone that received their jab
Is there a way to get your histamine levels checked?
Be sure to subscribe to channel. I did a video on this very controversial topic.
My son has Sibo and I am certain this is his main issue with high histamine in the brain.
This happened to me. Dx sibo after colon surgery. But my mental health spiraled uncontrollably. But I would never go the the psych ward bc they wouldn’t be able to accommodate my diet and I was afraid of being Dx eating disorder. Yes! It was histamine. And oxalates!
Does he have an MTHFR variant?
@@CatherineBenskindid you fix it
@@ej1coupeguy629 I eat a very restrictive diet, did a somatic trauma healing course and started seeing a psych nurse who deals with nutrient deficiency replacement and I am finally able to reduce my anxiety meds to where I was before the surgery and sibo. After my kidney stone and Christmas I’ll see if I can go further.
So what can one do.?
@@babsskett2757 please look at other videos on this channel as well as my blog www.DrHagmeyer.com
there’s a lot of information here and on website for you.
I DO respect an MD who is willing to have a patient attempt Alternative diet vs. straight to medication!! I would question those intolerant may have a genetic Polymorphism that would cause problems with that much protein (ie Methionine). These diets help many remedy their GI problems.
my previous rheumatologist put me on hydrocodone 3 to 4 times a day for itchy skin. I'm out. I have fibromyalgia and RA along with many symptoms of perimenpause but recently I've had worse symptoms. I wonder if it is kind of a withdrawal from running out of Hydroxyzine. I am really working hard to keep my mind busy because I itch all over very badly and I keep spacing out. Feels similar to a seizure but not exactly. I have a lot going on and now I don't know which doctor I should talk to
I live in the Netherlands and am 52 years old. I have an allergy for more than 20 years, but also sleeping problems at night and often extreme sleepiness during the day.
September this year I went to Jakarta Indonesia, one of the most polluted cities in the world, and guess what, this whole month the allergy symptoms were gone. No burning eyes, no sneezing and runny nose, no itchy skin and I slept like a baby, despite the extreme noise of this city.
All kind of things I thought of in the past - pollution, electro smog, cats - turned out to be not the problem.
Is there a solution? (Other than moving to Indonesia)
Is there any supplements to raise low histamine? My histamine is low as well as norepinephrine and epinephrine and serotonin. I have sleep issues and reaction time very slow. Mood is low anxiety all day. Feeling like I can’t balance my body. Any advice?
@@KathyChapman-y9g Amino acids like tyrosine and histadine, 5HTP
Sir is there a time to take these supplements individually? Like histadine? Or how long too take it? With food or at night? Thanks for responding. Really appreciate it.
I never thought of histamines as the root cause of some symptoms. My reaction to certain foods, chemicals, aerosols involves head spins, negative mood, sleepiness. Until now I didn't know what was the exact cause and process. Thank you
Root causes are SIBO SIFO or parasites in the gut leakygut is leakybrain to
Thank you! But how can I solve it?
@@wickyhaack5270 first test Breath test and test for leakygut. First stop with A1 milk and products and all gluten start eating real foods fres as possible if you can take have fruit eat is but as a snack 1/2 uur before or 3 hours after a meat and vegetable meal
Have you taken the histamine/ MCAS quiz
drhagmeyer.com/histamine-intolerance-quiz/
@@DrRichardHagmeyer I know this is another topic , I have GERD, gastritis , Erosion Esophagus ,
Low Stomach Acid , can you give your opinion , how to manage Low Stomach Acid ?
I know I can't be taking Apple Cider Vinegar because of Erosion Esophagus, it would burn the throat . Thank you very much. Debbie .
Thank you for the information, I appreciate it since knowledge is power, and health is precious.
Some years ago, I developed hives and angioedema (swelling of hands and left arm) due to a high intake of raw honey (mixed with organic full-fat yoghurt) -- which had soothed me during a time of emotional stress.
The high histamine level was probably the result of a severe copper deficiency because of the high intake of fructose day after day. The copper deficiency might have caused a low level of the DAO enzyme. Unfortunately, I can't remember how the high histamine level affected my brain.
I developed histamine issue from taking collagen supplements.
It’s a high histamine food. You most likely have histamine issues already and that just added to your load.
I have the Dao and HNMT variants. I only found out a couple years ago but I am now having major issues from them. 😢
Checkout some of the articles on my website about how to support DAO enzyme. It’s on my website (www.DrHagmeyer.com) under blogs or health articles! It’s just what you’re looking for!
Thank you. This was very informative. I know I have challenges with histamine and possibly MCAS. I recently started a carnivore diet and seen improvements and also now I take Beef Kidney for the DAO. My main challenge remains flushes once in a while. Also at night, if our cat wakes me, I will flush and it will take 15 minutes to cool back down. I get pretty good itching on the front of my left shoulder and this usually has one tiny pin prick sore in the middle. I do not get hives unless you can get a single hive or maybe two close together. They are not bumps. I am improving, yet still puzzled.
Are you familiar with the work of Dr. William Walsh and his findings on Methylation Status?
Help , My husband suffers from cluster headaches.I have heard that it has something to do with histamines . Anything New on them ?
I suggest you work with a certified functional medicine doctor. There is so much to histamine intolerance and MCAS. Most people are making themselves sicker!
can you experience HIT but not itch? Every time I eat papaya bananas I get tension headaches
You sure can! Their are 4 main
Histamine receptors. H1,2,3,4.
Itching/hives is associated with the H1 receptor. H2,3,4 are heart, neurological tissues, gut, lungs,
I have a slightly related question. Haven't noticed any of brain symptoms apart from restless mind. However, I did develop an alergy to milk 10 years ago, which is always present, as milk is everywhere and I never fully avoided it. I always have red spots on my body that migrate throughout months across different places on my skin. If it gets too difficult, I use mometason creams etс. How bad is it for me to have constant inflammation like this and is it possiblw to cure this allergy by obtaining from allergen for some time?
Chronic inflammation is a culprit in all diseases. You need to get it under control and needs to be a major focus!
Can histamine intolerance cause brain lesions, hypertension, and a stroke? Doctors at the ER couldn’t figure out the lesion’s in my brain, and they also found a 1 inch hiatal hernia. I don’t know how to resolve this, but I’m very scared because my blood pressure can’t be controlled even with medication. I also have high amounts of Candida and anxiety.
@pinkoceanflower3045 i really sugest gaps diet😊
@@stellaancimer8505 ♥️
Yes but there’s a-lot more to picture than that.
@@DrRichardHagmeyer what do you mean by that?
Mold exposure kills me! Since 2009 after lyme
Mold and Lyme?? That’s double trouble. 😬
Add long COVID, thata me
Memo: too much histamine in the brain can be really damaging
Hello mr. Richard am suffering from this kind of problem you pointed in your video, i have done of course of lot's of medicine past 6 months 😢, but after medicine over problem is there as it was,
.i have suffering symptoms like dry and itchy throat with fever like feeling in throat scratchy throat, fatigue muscles pain in whole body difficulty in rest also in sleeping, my doc proscribed me levocitizen & dihydrochloride 5mg that's help me temporary. 😢
please help me .
My odor causes others to have allergic symptoms like sneezing, coughing, and runny noses. Could this be related to the release of excessive histamine from my skin? I also have lesions in my brain, so I’m wondering if there might be a connection.
Does L- histidine relief brain fog?
It can.
Wow it affects appetite curious if that’s why I have barely any appetite first half of the day.
Any blood sugar issues? Insulin resistance?
For a decade I googled “what medication to take for flashpoint rage”
Could have saved some of my relationships and restored massive amounts of my mental peace and productivity if google had sooner given the answer: loratadine.
And yes, I’d been a psych patient for years. Anxiety, low key mania, delusions, compulsions/perseveration/distortions, distrust and paranoia, ideas of reference, explosive self harm, inability to concentrate or learn easily, chaotic, disorganised, socially impaired.
The gammut of medications, of which ONLY mirtazipine, olanzapine, and to a much lesser extent quetiapine actually treated my symptoms. But brought many side effects and issues both short and longer term.
OTC godsend thank you loratadine does it so much better than the “psych” meds.
So what is the solution to this? I keep thiking Ive lost my mind and its completely hopeless. It really feels like Im not all there mentally and I get comments from people at work 😩😩😩
Can high histamine cause Ear ringing? Tinnitus? 😮
Maybe- but rule out things like antibiotics, and ohter medications and high blood pressure
thinking of trying to help after dinner MSG headaches, by taking some anti-histamine OTC to reduce symptoms. I already take caffiene to counter the sleepiness, but that too can increase histamines? yes?
Which is the best antihistamine to take 😢
@@farhanbaig678 please look at other videos on this channel as well as my blog www.DrHagmeyer.com
there’s a lot of information here and on website for you.
If ypu take supplements like DAO will that help to lower histamine in the brain as well? Does all histamine originate in digestive system?
@@GVChristian DAO is an enzyme produced in the gut and works on histamine produced by bacteria as well as histamine ingested from
Food. Histamine in the brain is broken down by another enzyme HNMT. If you visit my website lots of articles on this! www.DrHagmeyer.com look under health articles or blogs
Thank you for this topic! ❤
You are so welcome!
I feel like when I have an allergy attack in spring I feel high appetite even before I take the antihistamind
Histamine can affect hunger signaling and leptin.
Im carnivore and loving it recently started histamine problems but im starting to think weening myself if cymbalta could be causing it by the sound of this video?!
Check out my article on the affects of keto on the microbiome! It’s under blog section.
My son has generalized epilepsy (severe) we were told benedryl and all antihistamines cause seizures. We took him off of it, he has awful allergies so he takes steroid nasal spray. Is there a test for histamine levels and mast cell levels?
Tryptase levels
Histamine
urine levels of N-methylhistamine
IgE total
Leukotriene E4 if you suspect MCAS
I’m struggling with constant hunger after taking fexofenadine for 5 months. I stopped it two months ago but the hunger isn’t going away. I don’t know what to do anymore.
This might help
6 Ways To Clear Histamine From Your Body- Strategies To Implement Today!
th-cam.com/video/Yc7AdvonWQU/w-d-xo.html
I will take my father to a allergist to see if he has high histamine, he has headaches all day runny nose , . Is this the doctor he should go?
@@RicardodelaFuente-t3r please look at other videos on this channel as well as my blog www.DrHagmeyer.com
there’s a lot of information here and on website for you.
lower the amino acid histidine which turns into histamine.
lower protein intake dramatically lowers histamine.......but it takes time.
Eat a small amount of meat......no need to be unnecessarily bulked up.
So how do you treat excess histamine in the brain and gut? You mention H blockers aren't enough and a low histamine diet isn't sustainable... So what do you do? You give no answer to this.
Take DAO enzyme with high histamine meals. It breaks it down.
I suffer from histamine intolerance as well for many tears and are really frustrated with this non-solution video!
Ben Lynch - seeking health
Fasting long enough to bring on autophagy is the best and really, the only way to repair the gut. Dr Paul Anderson has a video about this; he recommends at least a 5-day fast, water only.
Try Ashwagandha 💊