Friendly Neighborhood Immunologist
Friendly Neighborhood Immunologist
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Guillain barre | Molecular mimicry
Guillain barre is the main cause of short-term muscle weakness or the short-term inability to move your muscles. It is primarily caused by the bacteria Campylobacter jenjuni which is found in undercooked, infected chicken. One to three weeks after your immune system fights off the infection, the immune cells begin to target the nerves. This is due to molecular mimicry. The bacteria has a protein that looks almost exactly like the coating of your nerves. Therefore, the B cells, T cells, and macrophages begin to destroy the myelin coating around nerves and even destroy nerves themselves. Nerve destruction leads to the inability to move. Removing the antibodies that the B cells make seem to improve Guillain barre in 80% of people affected. The antibodies are removed through plasmapheresis (similar to dialysis). .
Sources:
www.ncbi.nlm.nih.gov/pmc/articles/PMC3755430/
www.cdc.gov/campylobacter/guillain-barre.html#:~:text=Infection%20with%20Campylobacter%20jejuni%2C%20which,the%20United%20States%20gets%20GBS.
มุมมอง: 1 428

วีดีโอ

How does Lyme Disease Happen?
มุมมอง 68611 หลายเดือนก่อน
Lyme disease is caused by black legged ticks also known as deer ticks. Lyme disease happens because ticks drink bacteria-infected blood from deer and mice in the wild. The deer and mice have Borrelia bacteria in their system which transfers to the ticks. Then when the ticks bite humans, the ticks transfer the bacteria to people. If caught quickly and treated with antibiotics, Lyme Disease can b...
T cells | Immunology Lecture | MHC-I versus MHC-II
มุมมอง 2.5Kปีที่แล้ว
This lecture is about T cells and major-histocompatibility complex I and II (MHC-I and MHC-II). The video will go over how T cells and antigen presenting cells fit together and activate. We will discuss where proteins come from to load into MHC-I (the cytosol) and MHC-II (vesicles). Furthermore, I will discuss the differences between CD4 and CD8 T cells. We will also cover positive and negative...
Immunology Lecture 5 | Pathogens and the immune response
มุมมอง 1.9Kปีที่แล้ว
Immunology lecture 5 is about pathogens and the immune response. Specifically the life cycles of bacteria, the Gram-stain, life cycles of RNA and DNA viruses. Then we will talk about which parts of the viruses and bacteria bind to toll-like receptors. Lastly we will cover other innate immune mechanisms of killing pathogens including reactive oxygen species such as superoxide and hydrogen peroxi...
Immunology Lecture 4 | Cytokines and Chemokines | Toll like receptor signaling NFkB
มุมมอง 7Kปีที่แล้ว
This lecture is about cytokines and chemokines as well as the toll-like receptor pathway. We will focus on Myd88 and NFkB and how toll-like receptor engagement causes most innate immune cell inflammation. The second half of the lecture will be about individual cytokines such as IL-1, IL-6 and TNF-a.
Immunology Lecture 3 | Innate immune cells | Leukocyte rolling adhesion
มุมมอง 2.5Kปีที่แล้ว
This is immunology lecture 3. We will cover innate immune cells including macrophages, neutrophils, basophils, and natural killer cells. Importantly, we will also cover how immune cells leave the blood stream and enter tissue, a process called leukocyte rolling adhesion. Here's a link to my favorite video about real immune cells during leukocyte rolling adhesion. th-cam.com/video/Ys6RlglMTMg/w-...
Immunology Lecture 2 | Primary and Secondary Lymphoid Organs and Blood (Hematopoiesis)
มุมมอง 4.5Kปีที่แล้ว
Immunology lecture 2 will cover both the primary and secondary lymphoid organs and the components of blood. We will briefly cover innate and adaptive immune cells, as well as granular versus agranular cells. Additionally, you will find information about hematopoiesis.
Immunology Lecture 1 | Brief History of Immunology
มุมมอง 10Kปีที่แล้ว
Welcome to my immunology lecture series! There will be 10 lectures about immunology. The first lecture will be a brief history of Immunology, including the discovery of the microscope, the smallpox vaccine, the cholera vaccine, and the polio vaccine. Additionally, we will talk about the discovery of antibodies and passive versus active immunity. The remaining lectures will be about Neuroimmunol...
Prion Disease | How does Prion Disease Happen
มุมมอง 85K2 ปีที่แล้ว
Prion Disease is caused by a single protein that makes a mistake and misfolds. If you want to know how Prion Disease happens then this video is for you. I will go over the top 3 most likely ways a person can get Prion Disease, what Prion proteins do in the body, and the role of the immune system in Prion Disease. Here are my sources: www.hopkinsmedicine.org/health/conditions-and-diseases/prion-...
Vitamin D and the Immune system
มุมมอง 25K2 ปีที่แล้ว
Vitamin D and the immune system work together. You might be surprised that vitamin D can boost and suppress the immune system. Vitamin D can boost primitive defenses of macrophages (Cathlecidin, LL-37, and Beta Defensins. However it reduces classic inflammatory cytokines like IL-1beta, Il-6, and TNF-a. Vitamin D also suppresses the adaptive immune system, B and T cells. This means that high lev...
ADE | What is Antibody Dependent Enhancement
มุมมอง 16K2 ปีที่แล้ว
Many people are wondering what is Antibody Dependent Enhancement or ADE. Antibody Dependent Enhancement (ADE) is a second key for a virus to enter your immune cells. Viruses have spike proteins that allow it to enter one or two types of cells like lung cells or neurons. That is the first key. If antibodies bind to a virus in a non-neutralizing way, the virus can enter immune cells called macrop...
How scientific papers are published
มุมมอง 1.6K2 ปีที่แล้ว
You might be wondering how scientific papers are published. I have published 12 scientific papers, and I can tell you the 7 steps need to publish a scientific paper. I have been accepted and rejected from scientific journals, and I will even show you my reviewer comments from two of my accepted papers. The review of research by other researchers is called peer-review. One peer reviewer is kind ...
A little bit about me
มุมมอง 3.7K2 ปีที่แล้ว
Hi! This is a video about my background, education, a few personal things. Hope it's interesting and helpful. B.S. Microbiology 2006 Ph.D Microbiology 2007-2012 - Studying T cells, microglia and bacteria Post-doctoral research 2012-2016 - Studying Alzheimer's disease and microglia Visiting Assistant Professor 2016-2021
APOE2 | APOE2 Longevity and Alzheimer's Disease
มุมมอง 5K2 ปีที่แล้ว
APOE2 is an important protein in the brain. APOE2 has been found to increase longevity in people as well as animals. APOE2 has been found to reduce the risk of Alzheimer's disease. The video is a requested video about doing a deep dive into APOE2. Overall, APOE2 reduces total cholesterol and increases activity which could be why people with APOE2 live longer on average. Review Paper APOE2: mole...
Natural Killer cells | Top 5 ways Natural Killer cells work
มุมมอง 32K2 ปีที่แล้ว
Natural killer cells are unique immune cells that kill virus infected and cancer cells. In this video, I will draw the top 5 ways Natural Killer cells work for you. Natural Killer cells are related to B cells and T cells, and interact with your "name tag," the MHC-I receptor that is on all of your cells except your red blood cells. The Natural Killer cell will spare any cell with your name tag,...
Valneva | How does Valneva work
มุมมอง 19K2 ปีที่แล้ว
Valneva | How does Valneva work
Autoimmune Encephalitis | What is Autoimmune Encephalitis
มุมมอง 23K2 ปีที่แล้ว
Autoimmune Encephalitis | What is Autoimmune Encephalitis
T cell memory | CD4 and CD8 T cell memory
มุมมอง 34K2 ปีที่แล้ว
T cell memory | CD4 and CD8 T cell memory
APOE4 | APOE4 versus APOE3
มุมมอง 14K2 ปีที่แล้ว
APOE4 | APOE4 versus APOE3
Novavax | How does Novavax work?
มุมมอง 299K2 ปีที่แล้ว
Novavax | How does Novavax work?
Alzheimer's drug Aduhelm explained | Aducanumab and Alzheimer's disease #Aduhelm
มุมมอง 6K2 ปีที่แล้ว
Alzheimer's drug Aduhelm explained | Aducanumab and Alzheimer's disease #Aduhelm
Alzheimer's disease and amyloid beta | Immune system and amyloid beta
มุมมอง 17K2 ปีที่แล้ว
Alzheimer's disease and amyloid beta | Immune system and amyloid beta
How do allergy shots work? | Th2 cells and IgE
มุมมอง 16K3 ปีที่แล้ว
How do allergy shots work? | Th2 cells and IgE
Why do allergies happen? | Immune cells and allergy
มุมมอง 5K3 ปีที่แล้ว
Why do allergies happen? | Immune cells and allergy
How does the immune system fight Cancer
มุมมอง 15K3 ปีที่แล้ว
How does the immune system fight Cancer
Don't want cancer? Be an elephant
มุมมอง 3.2K3 ปีที่แล้ว
Don't want cancer? Be an elephant
How does thrombocytopenia happen | Low platelets and the COVID vaccine
มุมมอง 24K3 ปีที่แล้ว
How does thrombocytopenia happen | Low platelets and the COVID vaccine
COVID Vaccine side effects are Good! *Mostly
มุมมอง 1.9K3 ปีที่แล้ว
COVID Vaccine side effects are Good! *Mostly
Don't take Tylenol before COVID mRNA vaccine
มุมมอง 3.6K3 ปีที่แล้ว
Don't take Tylenol before COVID mRNA vaccine
How does the COVID mRNA Vaccine work?
มุมมอง 19K3 ปีที่แล้ว
How does the COVID mRNA Vaccine work?

ความคิดเห็น

  • @JoannaDaniel-ov5hr
    @JoannaDaniel-ov5hr 20 ชั่วโมงที่ผ่านมา

    I almost lost it when i thought there's no hope for curing my herpes virus till i get connected to Dr Kuriama to get his wonderful herbs which truly worked like i ever imagined. All thanks 🎉 Dr Kuriama you're the best... ...

  • @ST80998
    @ST80998 วันที่ผ่านมา

    I live in florida and I have 18 different environmental allergies. I've get allergy shots every 2 weeks and I'm 7 months into the maintenance does and my sinuses swell up and get warm every single day. I'm still taking a crazy amount of antihistamines and one side of my nose has been closed for over 3 months. The only thing that will open my nose is a decongestant pill, which I've also been taking almost every day for about6 months, which I'd like to stop doing but it's literally the only thing that opens my sinuses......Do you think I'm someone who just doesn't respond to the shots? And how can I possibly keep my inflammation down when my sinusitis is so bad?

  • @starrs802
    @starrs802 2 วันที่ผ่านมา

    That sounds like a SEVIRE design flaw in the human body Like " death by normal chain reaction "

  • @wm9782
    @wm9782 2 วันที่ผ่านมา

    I wonder if some lab is playing with prion. Trying to make an anti ubiquiton Prions. Is it possible we will have a hyper prion attack one day? I pray not.

  • @SynistHer
    @SynistHer 2 วันที่ผ่านมา

    When one is both a scientist and a visual artist at heart you get amazing videos like this!

  • @siddarthsubba9284
    @siddarthsubba9284 5 วันที่ผ่านมา

    How many price this medicine

  • @theunfoldedtaquito
    @theunfoldedtaquito 10 วันที่ผ่านมา

    This is honestly the most incredible learning tool for immunology I’ve ever seen. No pretense, not over complicating topics, you just give the information in an engaging way. Thank you, I can’t wait to watch the rest.

  • @lmyers9999
    @lmyers9999 10 วันที่ผ่านมา

    Can I get my 10 min back?? Totally useless - why waste another 5 min on someone who recommends 400???? Idiot

  • @Droidzi
    @Droidzi 11 วันที่ผ่านมา

    stunning presentation - intriguing observations - thanks

  • @rob7041
    @rob7041 13 วันที่ผ่านมา

    "not to scale...that would be terrifying" lol Great work hope you continue with these.

  • @mohammedbaqer3706
    @mohammedbaqer3706 15 วันที่ผ่านมา

    Damn she’s pretty

  • @jank_memes
    @jank_memes 15 วันที่ผ่านมา

    Sounds like the theoretical strange matter in astro physics.

  • @surfinmuso37
    @surfinmuso37 16 วันที่ผ่านมา

    It hasn't been tested on the pregnant or breastfeeding yet they say it is safe for them and most Dr.s are pushing it. Does this not ring alarm bells? Vaccinated 95% less likely to get covid? This is clearly false. Everyone I know that got vaccinated has had covid AT LEAST once. Does not add up at all.

  • @rafelmelendez5876
    @rafelmelendez5876 18 วันที่ผ่านมา

    Thanks. Mine came with lupus.

  • @bluewave7120
    @bluewave7120 25 วันที่ผ่านมา

    I had this happen from undercooked chicken can a person fully recover over time without treatment? Do eggs carry this bacteria as well?

  • @MustangGaming87
    @MustangGaming87 25 วันที่ผ่านมา

    Forget food intake bla bla you all humans should take supplement of 5000iu D3 Daily year out. Whatever season. Or suffer later with diseases. Take a good magnesium with D3.

  • @barbararadon4796
    @barbararadon4796 26 วันที่ผ่านมา

    Still can cause myocarditides. Testing was still very short time. We still producing spike protein for how long? What kind of spike protea is against? Mutation is very fast in corona viruses and previous so called vaccine wasn’t vaccine but genetic treatment.

  • @SpeedGospel_Broadcast
    @SpeedGospel_Broadcast 26 วันที่ผ่านมา

    I'm very angry nobody is mentioning her beauty. What a beautiful soul😊😊

  • @akshaybhardwaj4846
    @akshaybhardwaj4846 26 วันที่ผ่านมา

    Thank you 😊🙏

  • @bonnenaturel6688
    @bonnenaturel6688 27 วันที่ผ่านมา

    Rare? Double prion disease causes many cases of Alzheimers. Studies have looked at the use of lithium, TUDCA, tuna oil (which is always pressed out of tuna on the store shelves so you get none of it) to name a few things that have been shown to reverse prion contagion in rat brains. There is no way this just started in our time at high rates as Alzheimers cases show (if double prion disease is in fact the cause of many cases of AD). All of the toxins in the air are my bet on how this disease is started. People have been eating meat for eons with very little disease.

  • @sabby123456789
    @sabby123456789 หลายเดือนก่อน

    My dad is an ApoE2/E4 and my mum is an ApoE3/E3. My two sisters are both ApoE2/E3, but I am an ApoE3/E4 🙁 The diet for ApoE4 is the hardest for me to follow. I do not mind eating raw oily fish that they serve in Japanese restaurants, but they are costly and they do have mercury and PCBs if you eat it too frequently. I tried to eat olive oil salads with avocados and lean chicken breast without saturated fat or carbohydrates for a while but I failed because it was not palatable. The lowest I ever got my cholesterol and LDL-C to purely by diet alone were 168 mg/dL and 86 mg/dL respectively, and I fell off of that diet after a month and everything went back up. I am considering taking medications to keep my cholesterol low so I do not have to be so restrictive on what I eat.

  • @SkylerFriedman-jg6df
    @SkylerFriedman-jg6df หลายเดือนก่อน

    Why doesnt exposure to allergens outside increase tolerance over time though? What is different about the shot?

  • @angelafulton7555
    @angelafulton7555 หลายเดือนก่อน

    unable to hear very well

  • @apriliafirdhadamayanti8273
    @apriliafirdhadamayanti8273 หลายเดือนก่อน

    Currently, amyloid beta can be detected in the blood, can this help treat Alzheimer's disease? So what factors influence the formation of beta amyloid in the body? thank you, your video is very very helpful😊

  • @princearuns.kamara5313
    @princearuns.kamara5313 หลายเดือนก่อน

    Thank you ❤

  • @tarapalmer9140
    @tarapalmer9140 หลายเดือนก่อน

    Many way for communicate u

  • @rjbond007
    @rjbond007 หลายเดือนก่อน

    seems like Rabies, you wouldn't know it until you are in your death bed.

  • @luckssj
    @luckssj หลายเดือนก่อน

    I also take Magnesium Glycinate and Phosphate and Liposomal Vitamin C so that D3 will work.

  • @fabianwahle5119
    @fabianwahle5119 หลายเดือนก่อน

    patiently waiting for the next video

  • @rajchoudhary1873
    @rajchoudhary1873 หลายเดือนก่อน

    After having infected from dengue platelets around 50k. No improvement from last 6 month's. Hematologist says antibody IFA weak positive

  • @Drobalar-Drsebi
    @Drobalar-Drsebi หลายเดือนก่อน

    You not only love your work but you also show care and comfort to all your patients, I want to thank you for the extra time you took to ensure my infection is completely gone. Your medication worked successfully, Thank you, Dr OBALAR

  • @seulflower
    @seulflower หลายเดือนก่อน

    28:50 we learnt in our immunology class that the innate immune system does in fact retains some sort of memory of the pathogens it encountered. this is called trained immunity, and apparently, it is a more recent concept which is why we dont see it mentioned in our immunology textbook often

    • @Noooneed
      @Noooneed หลายเดือนก่อน

      Thanks for pointing on this one .. sounds intersting ! I checked on it .. but still different of the memory response of Adaptive immunity

    • @seulflower
      @seulflower หลายเดือนก่อน

      @@Noooneed Yeah, it's more epigenetic and transient than our adaptive immune system's memory, but there are still some notable parallels in their fundamentals, such as antigen specificity (not exactly, but kinda, at least to a certain degree), immunological imprinting, enhanced activity upon re-exposure, and so on.

  • @JohnMyatt-ko5rz
    @JohnMyatt-ko5rz หลายเดือนก่อน

    Treatments like dog de wormers, dandelion root, ozone therapy should be researched more, not treatments that destroy your immune system.

  • @ritabaccellini714
    @ritabaccellini714 หลายเดือนก่อน

    No thanks keep them

  • @virithlol7197
    @virithlol7197 หลายเดือนก่อน

    You really are amazing and i appreciate this topic ❤

  • @consky3598
    @consky3598 หลายเดือนก่อน

    Simply excellent !!

  • @user-vx9de8xi8o
    @user-vx9de8xi8o หลายเดือนก่อน

    can spike protein act similarly to prion protein?

  • @biancast7149
    @biancast7149 หลายเดือนก่อน

    I think I can never eat sesame again after seeing this video

  • @georgeelgin3903
    @georgeelgin3903 หลายเดือนก่อน

    your hypothesis, that rates of thrombocytopenia might have been a result of mRna vaccines doesn't seem supportable in population studies. Evolutionary or Revolutionary ? i meant the immune system not eating less peanut butter.

  • @donnazukadley7300
    @donnazukadley7300 หลายเดือนก่อน

    The jabs

    • @Drobalar-Drsebi
      @Drobalar-Drsebi หลายเดือนก่อน

      You not only love your work but you also show care and comfort to all your patients, I want to thank you for the extra time you took to ensure my infection is completely gone. Your medication worked successfully, Thank you, Dr OBALAR

  • @jenniferswift2381
    @jenniferswift2381 หลายเดือนก่อน

    Wish someone would do a video on people who have Apoe 2/4, like me. I struggle with cholesterol, triglycerides, etc even when eating a really healthy diet. I’m 46. Just from the couple published studies I’ve read thus far, the 4 overshadows the 2. And I’m not sure the 2 even helps you if you have the 4 also. I have constant brain fog, headaches, etc. One published study I read from Alzheimer’s website said 2 is not totally benign and has increased risk of neurological disorders and cerebrovascular disease.

  • @elizabethharvester6111
    @elizabethharvester6111 หลายเดือนก่อน

    sorry but this was a little dry and required some pre knowledge about immune system before watching

  • @joyt458
    @joyt458 หลายเดือนก่อน

    Great explanation!

  • @jenniferswift2381
    @jenniferswift2381 2 หลายเดือนก่อน

    When you say you “have apoe4” does that mean 3/4 or 4/4?

    • @friendlyneighborhoodimmuno7192
      @friendlyneighborhoodimmuno7192 หลายเดือนก่อน

      I meant either one. Even one copy of apoe4 is a risk factor for AD.

    • @jenniferswift2381
      @jenniferswift2381 หลายเดือนก่อน

      @@friendlyneighborhoodimmuno7192 I just got my results back. I’m 2/4. Which is confusing because they say 2 protects against Alzheimer’s but apparently not if you have 4. According to published studies I read last night. The 4 is stronger than and overshadows the 2.

  • @user-vm3dv6dy2h
    @user-vm3dv6dy2h 2 หลายเดือนก่อน

    thanks for the explanation, we recently had a patient with this, turned out she has a teratoma!

    • @Drobalar-Drsebi
      @Drobalar-Drsebi หลายเดือนก่อน

      You not only love your work but you also show care and comfort to all your patients, I want to thank you for the extra time you took to ensure my infection is completely gone. Your medication worked successfully, Thank you, Dr OBALAR

  • @Irshadahmad-xs4og
    @Irshadahmad-xs4og 2 หลายเดือนก่อน

    Thanks you nailed it❤

  • @stephanyortega8345
    @stephanyortega8345 2 หลายเดือนก่อน

    Hi, I loved your video! Everything is clear and well-explained. Thank you so much! I have a question. Is it possible for different proteins to get unfolded by the contact with defective prions? I read something about amyloid beta, but I'm sure I didn't get it. 😢

  • @tobitheminnow
    @tobitheminnow 2 หลายเดือนก่อน

    Im learning this to make a oc lmao

  • @DrSoda.
    @DrSoda. 2 หลายเดือนก่อน

    Thanks, well done. With God, anything is possible. Jesus loves you!

  • @stevenverrall4527
    @stevenverrall4527 2 หลายเดือนก่อน

    Similar to the risk of being struck by lightning, so nothing to be concerned about. Worrying will increase your chances of getting cancer.