Regulation of Glycogen Metabolism

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In this lecture, EKG is going to cover the Regulation of Glycogen Metabolism-looking at how glycogenesis and glycogenolysis are regulated. We're going to break down the overview picture of how glycogen synthesis and degradation are integrated, the key enzymes involved, and how they are regulated allosterically and hormonally. Then we're going to zoom out to see the regulation of carbohydrate metabolism in the liver.
Lecture Overview:
0:00 Intro
0:30 Glycogen Synthesis/Degradation Pathway
1:45 Glycogen Phosphorylase Regulation
7:15 Glycogen Synthase Regulation
10:56 High Blood Glucose State
12:07 Low Blood Glucose State
✏️ All diagrams were made by EKG.
Lecture Source: Nelson, D. L., & Cox, M. (2017). Principles Biochem 7e (International Ed). Macmillan Publishers.
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