Can You Reverse Type 2 Diabetes? | Roy Taylor | The Proof Podcast EP

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  • เผยแพร่เมื่อ 25 มิ.ย. 2024
  • We’ve examined the complexities of type 2 diabetes many times on The Proof, learning from experts from across the world. Today, I sit down with a scientist who has fundamentally changed our understanding of this disease: Professor Roy Taylor. As one of the most esteemed scientists researching nutrition and metabolic health, Professor Taylor offers an absolute masterclass in what causes type 2 diabetes and the path towards remission for those managing it.
    👇 Visit The Proof website for the full show notes. 👇
    theproof.com/podcast/
    Professor Roy Taylor brings to the table not just his role as Professor of Medicine and Metabolism at Newcastle University but a track record of innovative research that has reshaped diabetes management. His pivotal 2011 discovery that type 2 diabetes could be reversed through the reduction of excess fat in the liver and pancreas sparked a transformation in treatment approaches, culminating in the implementation of the NHS Type 2 Diabetes Path to Remission programme. Beyond his clinical breakthroughs, Professor Taylor's contribution to the prevention of diabetes-related blindness in the UK and his authoritative publications have made him an influential voice in the conversation around diabetes and metabolic health.
    We discuss:
    00:00 - Introduction to the Twin Cycle Hypothesis & Onset of Diabetes
    02:25 - Delving into the Twin Cycle Hypothesis: Diabetes Aetiology Explained
    14:08 - Risks Associated with High Blood Glucose Levels
    20:53 - Key Factors Causing Insulin Resistance in Muscles
    26:14 - Understanding the Personal Fat Threshold in Diabetes Onset
    35:07 - Assessing the Risk Factors for Developing Type 2 Diabetes
    41:12 - Preventative Measures Against Type 2 Diabetes
    46:54 - Are Continuous Glucose Monitors Beneficial for Non-Diabetics?
    50:15 - Investigating the Determinants of Body Fat Distribution
    56:09 - Summary of the DiRECT Trial: Examining the Twin Cycle Hypothesis with Roy Taylor
    1:15:48 - Effective Strategies for Type 2 Diabetes Remission
    1:29:29 - The Role of Diet Quality in Insulin Sensitivity Improvement
    1:36:52 - Examining the Link Between Protein Consumption and Type 2 Diabetes
    1:39:34 - Incorporating Exercise into Type 2 Diabetes Remission Plans
    1:49:38 - The Possibility of Eradicating Type 2 Diabetes Societally
    1:53:24 - Understanding the Reversal of Type 2 Diabetes: Current Insights
    1:56:37 - Final Thoughts: The Prospects for Diabetes Management
    It was an absolute honour to have Professor Taylor on the show for this conversation. As a pioneer and highly respected figure in nutrition and diabetes research, his insight offers unparalleled clarity into both the simplicity and nuance of this prolific disease. If you found this episode valuable, please make sure to pass it on to someone who may benefit from it.
    Connect with Professor Roy Taylor:
    - Learn more about his work: go.ncl.ac.uk/diabetes-reversal
    - Life Without Diabetes book: amazon.com.au/Life-Without-Dia...
    - Your Simple Guide to Reversing Diabetes book: amazon.com.au/Your-Simple-Guid...
    If you have any additional questions you would like answered in the future, let me know in the comments.
    Optimise your health with InsideTracker’s biomarker analysis. Get exclusive access to InsideTracker’s new ApoB test and a 20% discount on your first order at insidetracker.com/simon
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    Enjoy, friends.
    Simon
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ความคิดเห็น • 179

  • @PlantChompers
    @PlantChompers 7 หลายเดือนก่อน +46

    So glad to see you interview him. I love what you wrote, that he has fundamentally changed our understanding of this disease. What a great interview.

    • @TheProofWithSimonHill
      @TheProofWithSimonHill  7 หลายเดือนก่อน +7

      His super power is studying mechanisms and using that to develop studies that look at hard health outcomes.

    • @soilikasanen
      @soilikasanen 6 หลายเดือนก่อน +2

      ​@@TheProofWithSimonHillStill he said the main defenition of a healthy diet is the low energy content - despite of the diet. By that defenition, any anorectic diet should be fine.
      Furthermore, he claimed that "extra carbs turn into saturated fat". I'd love to see him discussing with Cyrys Chiabatta (Ph.D. from Mastering Diabetes).
      He even said thar the only sane and enjoyable way to treat T2D is a restriction of carbs and calories.
      2 hr Interview without one mention of GLP-1 enhancing fiber and ad libitum low fat WFPBD!

    • @clownbackpainrick6581
      @clownbackpainrick6581 4 หลายเดือนก่อน

      @@soilikasanen
      It is obvious, that "By that defenition, any anorectic diet should be fine." is a too low energy content diet.
      And sure, it would be good to be proven, that keeping a good (low enough) energy is the single most important factor for being healthy.

    • @soilikasanen
      @soilikasanen 4 หลายเดือนก่อน

      @@clownbackpainrick6581 A calorie restricted chocolate cookie diet (developed in a study funded by meat industry) wasn't a healthy one, although participants lost weight a same amount than in calorie restricted intervention (lean beef) diet.

    • @myopenmind527
      @myopenmind527 3 หลายเดือนก่อน

      @@soilikasanenhe’s right and I’m the proof of it. I have reversed my diabetes by going on an ultralow (20g total carbs per day) and eating only real food. I eat both meat and plenty of non starchy vegetables.

  • @peterbedford2610
    @peterbedford2610 4 หลายเดือนก่อน +10

    Interviewing actual researchers is the best.
    I've learned a lot.
    Thanks

  • @DetroitHomeInspector
    @DetroitHomeInspector 6 หลายเดือนก่อน +8

    This advice worked for me. I was Keto-ish and lifting weights, I ate a lot and my weight stayed essentially the same and so did my A1C. I started eating carbs but focused on total calories and lost weight and my A1C dropped into the normal range.

  • @metalrunner4398
    @metalrunner4398 7 หลายเดือนก่อน +35

    Amazing interview Simon.
    As someone who was told that I am destined to get t2d in my 30s since all my family members had it, my trigs were 160, LDL 150 and fibroscan showed 67% of liver fat I can especially appreciate it.
    In 4 months I went to zero (0%) liver fat, trigs 42 and LDL and apoB both in low 60s. A1c 4.6%
    Nobody is destined to get t2d.
    My recipe was calorie deficit (in my case plant based high protein diet combined with cardio and weightlifting).

    • @Amshatelia88
      @Amshatelia88 7 หลายเดือนก่อน +6

      Congrats on taking control of your health!

    • @GlennMarshallnz
      @GlennMarshallnz 7 หลายเดือนก่อน +1

      Hi, congratulations and well done. What does your average daily diet consist of?

    • @metalrunner4398
      @metalrunner4398 7 หลายเดือนก่อน +4

      @@GlennMarshallnz pretty much what dietary guidelines say but my protein sources are seitan, tofu, tempeh, tvp, mock meats and my dairy source is calcium fortified soy milk.

    • @GlennMarshallnz
      @GlennMarshallnz 7 หลายเดือนก่อน +2

      @@metalrunner4398 Hi, thanks for your response. So are you 100% plant based, or do you consume some animal products and if so what? My LDL is over 300 and triglycerides are at 80. I’m 53 good weight and do HIIT cardio x3 times per week and strength training x3 per week as well. I’ve switched to a WFPB diet plus calcium fortified unsweetened soy milk plus one small can of sardines in water each day for omega 3, b12, and iodine. I’m hoping to more than halve my results in three months time. Regards Glenn

    • @metalrunner4398
      @metalrunner4398 7 หลายเดือนก่อน +2

      @@GlennMarshallnz I am
      100% pb but I do supplement with algae oil (DHA/EPA). Also, I occassionally do eat mussels since I am purely ethical vegan so have no trouble eating non sentient animals.

  • @paulbainjr
    @paulbainjr 7 หลายเดือนก่อน +19

    I bought doctor Taylor’s audible book, this makes the most sense I’ve been a diabetic 35 years. Drastically reducing my calories for 10 weeks makes so much sense. My a1c went from 13 to 6.5 .

    • @roadguide123
      @roadguide123 6 หลายเดือนก่อน +2

      Good job... congrats 🎉

    • @jameshunt7884
      @jameshunt7884 6 หลายเดือนก่อน +1

      How u doing now

    • @paulbainjr
      @paulbainjr 6 หลายเดือนก่อน +3

      Hi I’m doing great I keep my carbohydrates low calories about 1700 lost 40 pounds. Blood sugar 80 -120 Average. A1C still hovers at 6.2 😊

    • @jameshunt7884
      @jameshunt7884 6 หลายเดือนก่อน

      @paulbainjr good effort from new Zealand

    • @jameshunt7884
      @jameshunt7884 5 หลายเดือนก่อน +1

      35 years been diabetes and u changed that quickly

  • @aminreviews2311
    @aminreviews2311 6 หลายเดือนก่อน +7

    Simon is an outstanding interviewer. Knowledgeable, well read, and excellent manner of leading the discussion and allowing the guest to talk!

    • @potterylady44
      @potterylady44 5 หลายเดือนก่อน

      He really is!❤

  • @elizabethdudenhausen3541
    @elizabethdudenhausen3541 7 หลายเดือนก่อน +20

    Another fascinating discussion.
    The concept of individual fat threshold blew open my head.
    I am a retired scientist who studied liver cancer metabolism but I had never considered this concept of liver fat metabolism and T2D.
    Yikes!
    I am an exercising, slim ( low BMI)
    woman with test indications of preT2D.
    Bingo!
    Thanks for the revelations!

  • @MemoryAmethyst
    @MemoryAmethyst 7 หลายเดือนก่อน +11

    Excellent interview. So great to hear both the interviewer and the interviewee talking at a normal rate. It really helps the listeners to assimilate the knowledge imparted.

  • @prestomattwine
    @prestomattwine 3 หลายเดือนก่อน +4

    Thanks for the advice. But as a person with insulin resistance and pre diabetes, why are a lot of these videos always talking about people who don’t have insulin resistance or diabetes talking about how to reduce their chances, which is fine, but we need more videos on how to reverse diabetes for those people who already have it.

  • @FightBackAgainstDiabetes
    @FightBackAgainstDiabetes 7 หลายเดือนก่อน +8

    *You Did Not Choose To Be Classified As Diabetic, But You Can Choose To Fight Back Against Diabetes* 💪

  • @sardalamit
    @sardalamit 6 หลายเดือนก่อน +5

    Am typing this as I'm listening. I like your format of summarising everything he's saying after every few points. Very helpful. Subscribed.

  • @DrMohammadHasani
    @DrMohammadHasani 11 วันที่ผ่านมา

    my man thank you for inviting roy to your podcast

  • @aydat7880
    @aydat7880 7 หลายเดือนก่อน +10

    Thanks a lot because of interviewing such brilliant scientist which is a very unique characteristic of your podcast 🙏🌷👌

  • @LoriTildenLeeke
    @LoriTildenLeeke 5 หลายเดือนก่อน +3

    An other person to interview on the topic of reversing Type II diabetes is Marty Kendall of @OptimisingNutrition
    He’s got the proof, the data, and the testimonials.
    Please, bring him on as an interview guest!

  • @kst157
    @kst157 7 หลายเดือนก่อน +8

    First class interview & detailed & relevant discussion - lots of ‘wow’ moments & expertly communicated. Thank you both. :)

  • @catherinebell122
    @catherinebell122 7 หลายเดือนก่อน +8

    Yes, this audio is great. I listen again and sincerely appreciate the conversation. Hopefully, there will be more to come on this topic. Thank you for this episode! 😎👏🏻

  • @user-fk8rb8ue5h
    @user-fk8rb8ue5h 4 หลายเดือนก่อน +1

    Absolute brilliant from Professor Taylor. No BS or dogma.just evidence based proof.

  • @TinaD-xj7qm
    @TinaD-xj7qm 14 วันที่ผ่านมา +1

    Best interview ever

  • @leahblackburn3872
    @leahblackburn3872 7 หลายเดือนก่อน +3

    Audio is great, thank you. Looking forward to listening to this later. Thanks again for all the amazing conversations. I learn so much.

  • @yeti9127
    @yeti9127 7 หลายเดือนก่อน +4

    Yes I did reverse mine naturally and went medicine free through proper nutrition, exercise, and stress management.

    • @jameshunt7884
      @jameshunt7884 5 หลายเดือนก่อน

      How u getting on now did u fallow dr ken berry to

    • @yeti9127
      @yeti9127 5 หลายเดือนก่อน

      @@jameshunt7884 I watched a lot of videos, read a lot of papers, and a few books. I basically did a lot of trials with various types of low carb food. Then healthy fat - olive oil, nuts, fish etc. then starting log in 10000 steps a day.

  • @MrRibbett454
    @MrRibbett454 7 หลายเดือนก่อน +5

    Superb interview and guest. Half way through it and learning so much. Cheers

  • @wendy1908
    @wendy1908 6 หลายเดือนก่อน +1

    Great episode, thank you.

  • @mhtyler
    @mhtyler 5 หลายเดือนก่อน +1

    Thanks for asking Dr/Prof Roy many of the questions I wanted to ask him myself!

  • @TheProofWithSimonHill
    @TheProofWithSimonHill  6 หลายเดือนก่อน

    Hi Friends,
    Curious to know - which part of our recent conversation did you find the most engaging? Also, if there are any other questions you have in mind about this topic, just leave them below. I'll ensure they're included in our next chat.

  • @black_knight_1975
    @black_knight_1975 3 หลายเดือนก่อน +1

    This was such a great interview. What an amazing man Roy is!

  • @joedaw3003
    @joedaw3003 7 หลายเดือนก่อน +2

    Thank you Professor Taylor . Greetings from Singapore. I love your book. It is on my Audible and Kindle. Inspirational and enlightening. I limited my food intake to 800 calories per day and lost weight and reversed my diabetes in early 2022. Thank you and I hope the world will adopt your twin cycle hypothesis and the results to treat diabetes.

    • @clownbackpainrick6581
      @clownbackpainrick6581 4 หลายเดือนก่อน

      Hi Joe,
      what were your markers at baseline and where are they now ?
      (weight, waist circumference, LDL, HDL, fasting bloog glucose, HbA1c...)
      In the original direct study there were 89 participants. After the 12 weeks of 800 kcal per day there were 50% into T2D remission. A follow up for 5 years showed that only 11 participants (12%) were T2D free.
      What are in your mind the most important factors, why most people cannot stick to a healthy diet. As in this case they had diabetes and did feel the bad outcomes.
      Then they got the "wonder" to be diabetes free, but most of them could not stick to it...

  • @sunnyhawk
    @sunnyhawk 6 หลายเดือนก่อน

    Fantastic interview. Roy Taylor may be my favorite guest you've had on. Please do that part 2!

  • @nadege_diercks
    @nadege_diercks 7 หลายเดือนก่อน +1

    Great podcast, thanks a lot Simon!

  • @alblee
    @alblee 7 หลายเดือนก่อน +2

    A better version here. Thanks!

  • @mattzilla331
    @mattzilla331 7 หลายเดือนก่อน +8

    He has a great voice. He should read for audio books

    • @TheProofWithSimonHill
      @TheProofWithSimonHill  7 หลายเดือนก่อน +2

      I think so too!

    • @Amshatelia88
      @Amshatelia88 7 หลายเดือนก่อน +3

      He really does, I love his accent.

    • @sodopianos1412
      @sodopianos1412 7 หลายเดือนก่อน +1

      No! It’s too perfect.

    • @melimoo6656
      @melimoo6656 5 หลายเดือนก่อน

      He narrates his audiobook

  • @malvanlondon8683
    @malvanlondon8683 4 หลายเดือนก่อน +1

    A very good, comprehensive discussion. Thank you.

  • @nutrizione_vegetale_in_pratica
    @nutrizione_vegetale_in_pratica 7 หลายเดือนก่อน +1

    Thank you so much for this conversation! That topic was my dissertation subject. So fascinating. And here so perfectly explained! I maybe think the exercise contribution is a little bit underestimated (as well as the specific fat composition of the diet) based on what I could read while researching.

  • @thetransferaccount4586
    @thetransferaccount4586 5 หลายเดือนก่อน +1

    wonderful informative podcast, host has done good homework, we rarely see these days

  • @nolawebster721
    @nolawebster721 7 หลายเดือนก่อน +2

    A very useful / informative discussion , thankyou 👍

  • @azdhan
    @azdhan 7 หลายเดือนก่อน +4

    This was so informative, educational, and interesting. Many thanks Simon and many thanks to the good professor. I always understood/thought that yo yo dieting was bad as some reputable people like Layne Norton have said that it messes with the metabolism in a way that can accelerate fat rebound faster with every yo yo cycle. And worse, can make it harder to lose the regained fat. You end up having to cut calories more and more to lose the same amount of fat that you could previously more easily lose with a higher calorie consumption, all other things being equal. One solution is reverse dieting but sometimes in people who have yo yo dieted for so long they literally have to reverse diet for a long time and endure the increased fat increase, to “fix” their metabolism so when they go on a fat loss phase again, it becomes easier to again lose fat without having to drastically cut calories
    Also, I know Professor Taylor touched on BMI as being an imperfect measure. While the measure is commonly still used, it is recognized that BMI index has to be modified for certain populations. Case in point:
    The way BMI is calculated for South Asians is different to the way in which it is calculated for people with a European background.
    The reason for this is that South Asians have been found to be more at risk of the problems of being overweight such as type 2 diabetes and heart disease.
    The BMI cut offs for South Asians as it relates to what is consderef healthy BMI are much lower
    Below 18.5 is Underweight
    18.5 to 22.9 is Healthy weight
    Anything over 22.9 is considered unhealthy

  • @terrymeland9989
    @terrymeland9989 7 หลายเดือนก่อน +4

    Great interview. A lot of simple, practical advice.
    Would be nice if the full transcripts of your interviews was available on your website.

    • @Amshatelia88
      @Amshatelia88 7 หลายเดือนก่อน +1

      Transcripts would be FANTASTIC!

    • @TheProofWithSimonHill
      @TheProofWithSimonHill  7 หลายเดือนก่อน +2

      Coming soon!

    • @terrymeland9989
      @terrymeland9989 7 หลายเดือนก่อน +1

      @@TheProofWithSimonHill much appreciated.

  • @LaurenKomishane
    @LaurenKomishane 7 หลายเดือนก่อน +6

    Thank you for this informative interview Simon. I found it interesting to understand important nuances in each individual in terms of how glucose and fat are stored. Loved listening to his experiment descriptions to understand how much weight loss is needed to reverse type 2 diabetes. A great podcast to jumpstart a new health journey or to understand how we might help each other improve health.

  • @kostaspapazoglou2851
    @kostaspapazoglou2851 7 หลายเดือนก่อน +2

    Your intrinsic, inquisitive nature for knowledge and information in order to enhance health outcomes and benefits has, once again, brought out the best of your guest. Beyond his theoretical education, his unambiguous and practical advice should provide a stimulus to everyone to be mindful of the "Twin Cycle Hypothesis" and the ensuing "metabolic devil"!

  • @astonuk9403
    @astonuk9403 7 หลายเดือนก่อน

    Great discussion. What of liked more in depth talk on the type of fatty acids and how they affect the liver and inflammatory pathways.
    Long-chain fatty acids, particularly saturated fats like C16 (palmitic acid) and C18 (stearic acid) are associated with type 2 diabetes. These fatty acids undergo metabolism within the body, leading to the formation of lipid intermediates like diacylglycerol (DAG) and ceramides. This metabolic process can activate protein kinase C (PKC), disrupting insulin signaling pathways and contributing to insulin resistance.
    Inflammatory pathways also come into play, particularly with palmitic acid activating the nuclear factor-kappa B (NF-KB) pathway. This activation leads to the production of pro-inflammatory cytokines, such as tumor necrosis factor-alpha (TNF-a) and interleukin-6 (IL-6), contributing to chronic inflammation associated with insulin resistance.
    Contrastingly, unsaturated fats, including monounsaturated and polyunsaturated fats, exhibit different metabolic effects. They are less prone to forming lipid intermediates and do not activate PKC to the same extent as saturated fats. Additionally, they promote lipid oxidation and help prevent the accumulation of lipids in tissues from what I've read.

  • @RiDankulous
    @RiDankulous 7 หลายเดือนก่อน +1

    I previously found your channel through the channel called nutrition made simple. These two channels it really helped me understand an Unbiased viewpoint to temper my knowledge of the whole food plant-based diet. It was good that I follow the channels for that Diet because I’m a be healthy. There is some misinformation in there though and this helps clear it up.
    This doctor seems to be pretty well Excepted as an authority on the mechanism of diabetes and trial tested solutions and decent size groups it

  • @TommysPianoCorner
    @TommysPianoCorner 7 หลายเดือนก่อน +1

    Dr Taylor’s work is truly amazing. However, I’m not sure it has all the answers. When we consider that remission is defined as an A1C below 6.4, whilst this might be below the diagnosis threshold, anyone with an A1C above 5.7 (and arguably that is a high number), is definitely unwell! So, the weight loss definitely helps but it does not seem to fix the underlying problem.

  • @Briscoe1975
    @Briscoe1975 7 หลายเดือนก่อน +3

    This guy has a wealth of knowledge!
    QUESTION for Simon.
    I’m a father of a 6yo T1D and our family is vegetarian. So the way carbs react to his BG is very important. You asked the Dr if there was an advantage to eating your protein before you eat your carbs. I don’t think he really addressed this fully. Should he be eating the protein on his plate before the carbs? He will devour his fruit first because he loves fruit.
    Thoughts?

    • @dinamariea61
      @dinamariea61 5 หลายเดือนก่อน

      I also recommend that you ask this question to the Mastering Diabetes folks as well. They do live shows on TH-cam frequently and check the chat for questions. Here is the link: youtube.com/@MasteringDiabetes?si=MQ0fAS3F9-ckWWnc

  • @Ricky-bl7yz
    @Ricky-bl7yz 6 หลายเดือนก่อน

    Waist Hip Ratio is also a very good predictor of risk of type 2 diabetes! Waist Hip ratio is a good indicator of amount of organ fat and Prof. Taylor’s have demonstrated that that’s one of the major causes of type 2 diabetes. All you have to divide your waist circumference to your hip circumference.

  • @stephennickles7389
    @stephennickles7389 10 วันที่ผ่านมา

    I follow Mastering Diabetes and Prof. Roy Taylor's guidance, dropped 33lbs, A1c came down to pre-diabetes range. Vigilance is the key, however, like "Cypher", I reenter the "Matrix" on occasion and have a taste of forbidden food, it usually takes a week to fight my way back to goal weight, fortunately my sugar doesn't skyrocket, exercise?

  • @jp7357
    @jp7357 7 หลายเดือนก่อน

    Great YT. really good data on exercising fasted … I run 3.5mi fasted for fat and 2.5 before dinner for glucose control … just see,med like a good idea … appreciate the validation

    • @clownbackpainrick6581
      @clownbackpainrick6581 4 หลายเดือนก่อน

      To get your blood glucose down, it would be better to do excerise after your meal (a brisk walks e.g.).

  • @sherri.
    @sherri. 3 หลายเดือนก่อน

    Yes.

  • @evanhadkins5532
    @evanhadkins5532 5 หลายเดือนก่อน

    I heard of Roy's work soon after being diagnosed with T2D. I was one of the lucky ones - picked up early and now in remission. So I probably owe him my health. I didn't bother with meal replacements though (for one thing I'm not wealthy) just eliminated added sugar and the problematic grains and went for a daily walk. Which lead to the needed weight loss.

    • @clownbackpainrick6581
      @clownbackpainrick6581 4 หลายเดือนก่อน

      Hi, have you been in his study as participant ("direct" study)?

    • @evanhadkins5532
      @evanhadkins5532 4 หลายเดือนก่อน

      @@clownbackpainrick6581 No, just followed the guidelines in the book.

  • @bb2021
    @bb2021 3 หลายเดือนก่อน

    Can anyone post the link to the sedentary - half Great North Run study Prof Taylor mentioned towards the end please?

  • @leviotten
    @leviotten 4 หลายเดือนก่อน

    im an example of the normal-ish BMI range (only 8lbs overweight when diagnosed), but I have T2.
    As soon as I lost about 25lbs, down to 165lbs, my blood glucose has largely regulated. I still get fairly wild spikes but my HbA1C is below range (generally post-prandial 5.8-6.1).

  • @jameshunt7884
    @jameshunt7884 6 หลายเดือนก่อน

    Wish this information would get onto medical people in new Zealand only one doc has herd of these guys i have came a cross and he young doc

  • @aeronhong4998
    @aeronhong4998 7 หลายเดือนก่อน +1

    This audio is good. 👍

    • @TheProofWithSimonHill
      @TheProofWithSimonHill  7 หลายเดือนก่อน

      Glad you think so!

    • @aeronhong4998
      @aeronhong4998 7 หลายเดือนก่อน

      @@TheProofWithSimonHill pls continue with your superb content. 🙏

  • @jameshunt7884
    @jameshunt7884 5 หลายเดือนก่อน +1

    Where do u get these low calorie drinks roy talking about from new Zealand

  • @gabymalembe
    @gabymalembe 7 หลายเดือนก่อน

    I use s cgm to reduce glucose spikes, and it’s lots of fun. Don’t know if it matters.

  • @johnathanwetherill456
    @johnathanwetherill456 7 หลายเดือนก่อน

    Much better . Its still there but thanks for your effort . One thing that might have helped if you noticed when he started talking during the interview is to ask him to move the mic away from the front of his mouth .

  • @mkkrupp2462
    @mkkrupp2462 7 หลายเดือนก่อน

    I read where many well heeled diabetics in India (who are not necessarily grossly overweight) are opting for bariatric surgery as a matter of course.

  • @leandrobecker123
    @leandrobecker123 7 หลายเดือนก่อน +1

    Congratulations for the guest that you invited! I like a lot dr. Roy Taylor. I have his book.
    Respectfully i will disagree about min 44. In my opinion you can better understand someone's metabolic status besides the tradicional markers cited. For example I like to use kraft test (insulin curve after 75 gr glucose) . CGM also agre

    • @leandrobecker123
      @leandrobecker123 7 หลายเดือนก่อน +1

      Also aggregate because you can understand if your personal diet is in some moment of the day spiking your glucose (and subsequently insulin level). MRI also helps in showing to patient the relative subcutaneous x visceral fat - something very well explained by dr. Sean Omara.

  • @kazoz3520
    @kazoz3520 7 หลายเดือนก่อน +2

    1:35:23 I found this answer fascinating...
    1:35:53 Prof Roy Taylor: "Overnight you'll put out 10 grams per hour [glucose] for the average man, in average health. But with diabetes you are putting out about 15g /hr. So it's not to do with the food. You're looking at metabolism determining the blood glucose level."
    Lol, I listened to an anti-carbs video where the argument given was that seeing a healthy person has a total of 10 grams of glucose in the blood (in the whole body), you don't need more than 10 grams of glucose from your diet 😊

    • @clownbackpainrick6581
      @clownbackpainrick6581 4 หลายเดือนก่อน

      I do not get, what you want to express with that.
      In the above section you write g/hr and down you write gramms only.
      If it is 10 gramms per hour both, that what is the difference?

    • @kazoz3520
      @kazoz3520 4 หลายเดือนก่อน

      @@clownbackpainrick6581 They were confusing the body function of keeping blood glucose levels at a constant (eg 10g), to the amount of glucose utilised over time. Ie, they left out metabolism from the argument, just said the whole body has 10g in the blood, therefore only need a couple of teaspoons worth of sugar.

  • @YK-Youtube
    @YK-Youtube 7 หลายเดือนก่อน

    A lot of great questions you asked aa always!! Thank you. In Japan there is type 2 diabetes due to aging - decrease of insulin and some other factors. I am afraid of that as my father has it. I want to keep insulin sensitivity up. I wonder how..Any insights???

    • @TheProofWithSimonHill
      @TheProofWithSimonHill  7 หลายเดือนก่อน +2

      Exercise, appropriate calories and a healthy dietary pattern.

    • @YK-Youtube
      @YK-Youtube 7 หลายเดือนก่อน +1

      @@TheProofWithSimonHill Thank you! T2D solution often goes to weight loss. I am trying to build muscles and telling my father too. I love all sort of exercise. I used to feel guilty taking out time from work or saying no to meetings with my clients. But now I say "medical neccesity for my physical & mental" !!

  • @robz.3225
    @robz.3225 7 หลายเดือนก่อน

    I've been told the opposite about complex carbs. What does the research say about this?

  • @lauried4439
    @lauried4439 2 หลายเดือนก่อน

    Might there be a personal fat threshold for other chronic diseases, like asthma, or is any excess fat generally inflammatory?

  • @MrRibbett454
    @MrRibbett454 7 หลายเดือนก่อน +1

    Audio good

  • @carljenkins259
    @carljenkins259 4 หลายเดือนก่อน

    I have a question about insulin. Do we produce the same amount of insulin if blood glucose rises are flatter when we combine foods to mitigate the spikes. For example, eating white rice on it's own would proabably cause a higher glucose rise than if you combine the rice with meat and non-starchy veg. But because we are ingesting the same amont of refined carbs, do we still need the same amount of insulin or is it less as glucose won't rise as fast? Hope that makes sense?!

  • @RXP91
    @RXP91 7 หลายเดือนก่อน +3

    EPIC conversation and one with real world health implications for me. My entire family has Type II and my HB1ac isn't great despite strength training for 20 years and being an endurance athlete. When I was truly WFPB I was down at 56kg - only 3kg higher than my 18 year old weight, which is likely extra muscle anyway. So back I go to 56kg and hope societal sitgma about being a thin male doesn't effect me as much in my 30s as it did in my 20s.
    Also it's interesting why Indians have that history of famine. It wasn't natural and it was entirely because of the British empire: th-cam.com/video/z8Qv7zZBxq8/w-d-xo.htmlsi=qoJO6ohhvw0miwdh. You are born with your genes & you have to do the best, but it feels really unfair when the gun was loaded against you by colonists

  • @aroundandround
    @aroundandround 4 หลายเดือนก่อน

    6:45 I don’t understand how, if “fat stops the insulin producing cells from working properly” (presumably meaning insufficient insulin) on the cycle on the right causing blood glucose to rise, insulin is happily being released in sufficient quantities on the left to convert blood glucose to fat.

  • @Seanonyoutube
    @Seanonyoutube 7 หลายเดือนก่อน +3

    Interesting that the longest remission case he followed is only 19 years. I wonder how old that person is. I would be interested for you to speak with a researcher who can discuss with you the specific phenomenon of diabetes that comes with old age even without accumulating weight. Also old age hypertension and other metabolic old age issues that often happen absent of weight gain (sometimes even with weight *loss*)

    • @trotskyite1
      @trotskyite1 7 หลายเดือนก่อน

      No weight gain just fat gain

    • @Seanonyoutube
      @Seanonyoutube 7 หลายเดือนก่อน +1

      @@trotskyite1 no, there are many old people who get diabetes late in life even with very little fat.

    • @harvinderubhi5540
      @harvinderubhi5540 7 หลายเดือนก่อน

      ​@@Seanonyoutubelittle dietary fat??

    • @Seanonyoutube
      @Seanonyoutube 7 หลายเดือนก่อน

      @@harvinderubhi5540 I was talking about body fat

    • @clownbackpainrick6581
      @clownbackpainrick6581 4 หลายเดือนก่อน

      Hi Sean,
      older people have longer time to damage their metabolism/tissue through false lifestyle.
      This is a possible answer to your suggestion.
      >>DOI: 10.1111/j.1464-5491.2005.01655.x
      Are insulin resistance, impaired fasting glucose and
      impaired glucose tolerance all equally strongly
      related to age

  • @ladagspa2008
    @ladagspa2008 6 หลายเดือนก่อน

    Good topic - thanks. Quite a simple treatment really, lose weight and keep it off.

  • @alisonjane5364
    @alisonjane5364 7 หลายเดือนก่อน

    Surely fasting insulin is the only test needed to see if someone has reached their fat threshold. Although, from what I've heard, they have set the acceptable level too high. Much higher than what Joseph Kraft recommended.

  • @user-jk3zp6mi8d
    @user-jk3zp6mi8d 7 หลายเดือนก่อน

    If pancreatic fat overload reduces insulin output, why do we measure insulin resistance by looking for elevated fasting insulin levels?

  • @frederickkrewson638
    @frederickkrewson638 7 หลายเดือนก่อน +3

    Simon - This seems extraordinary. A 100% cure for Type 2 Diabetes for 5 out of 6 people!! ( You simply must lose 8 or 10 kilos...and make the decision to keep the weight off). That seems like such a simple question...do you want to be diabetic of not? ( it all depends on the individual and whether they are willing to simply control their weight ). Why isn't this information being broadcast on all major channels and endorsed by all the doctors??

    • @yangtse55
      @yangtse55 7 หลายเดือนก่อน

      The medical profession is jaded. Underfunded and faced with patients lacking motivation
      For me, being briefly labelled "diabetic" was sufficient motivation to lose a quarter of my bodyweight but even with near-perfect metrics, being over- 60, the medical profession will not leave me alone and tried offering me statins at one point and recently ignored what I told them about massive anxiety and claimed to see an upward trend in BP based on no real history and a handful of white coat readings...
      Four years and 25 kilos from my last bad blood glucose reading I recently benefited by being given covid and flu vaccines I would otherwise not have been entitled to in the UK .
      The UK population based QRISK calculator even adds 1 percent to heart risk based on POST CODE !

    • @wifeofpierre
      @wifeofpierre 5 หลายเดือนก่อน

      @@yangtse55GPS are paid £5 per person they put on to statins.

  • @madcircle7311
    @madcircle7311 7 หลายเดือนก่อน

    Wait is this a reupload

    • @TheProofWithSimonHill
      @TheProofWithSimonHill  7 หลายเดือนก่อน +1

      Just improved audio. But it’s this weeks ep! Recorded it a few weeks ago

  • @kevinbrannan8347
    @kevinbrannan8347 7 หลายเดือนก่อน

    What if the glucose causes the fat , to many carbohydrates as they raise blood glucose, eating fat doesn’t raise glucose. Check that out

    • @TheProofWithSimonHill
      @TheProofWithSimonHill  6 หลายเดือนก่อน +1

      Excess calories, be it from glucose or fat, will increase hepatic fat. Saturated fats seem particularly deleterious

  • @tomhermens7698
    @tomhermens7698 3 หลายเดือนก่อน

    You suggest fastening other sites say eat a little every 3 hours, others say no meat etc. All very contradictory.

  • @seitanbeatsyourmeat666
    @seitanbeatsyourmeat666 7 หลายเดือนก่อน +1

    🚨 Plant Chompers just put a video out about PFAS and it’s beyond alarming. I’d love your opinion on it
    I’m …I’m a little alarmed tbh

    • @TheProofWithSimonHill
      @TheProofWithSimonHill  7 หลายเดือนก่อน +1

      I will add that to the list of future topics!

    • @BowenUSA
      @BowenUSA 7 หลายเดือนก่อน +2

      Peter Rogers MD (YT channel) covers toxicology as the elephant in the room even in Whole Food Plant Based diets. The careful consumer can mostly avoid hyperpalatable foods that are excitotoxic to the brain, although MSG (and 'regrettable replacements') is hidden in our modern food labeling scheme as "Natural Flavor."

  • @docbegone1716
    @docbegone1716 7 หลายเดือนก่อน +29

    Sounds like the whole video could be summed up in three sentences: Stop eating processed "food":, stop eating refined "food" (sugar, oils, fat etc..) , stop eat fatty food, and start eating food that we were all meant to eat. Sounds like Whole Food Plant Based to me. Eat properly and dramatically lower your risk of ever contacting any of the "diseases" that unfortunately and unnecessarily plagues most of the world's population today.

    • @docbegone1716
      @docbegone1716 7 หลายเดือนก่อน +3

      Sounds good. I don't eat any processed oils except for every third or forth week I might make popcorn with organic popcorn kernels I buy, and then I add a teaspoon of flax seed oil so that my spices that I also add will stick to the popcorn . I also add a little apple cider vinegar for some extra sticking power as well. I easily eat three handful of nuts a day. I use a seed grinder and grind up flax seed, chia seed, a brazil nut, peanuts, sunflower seeds, sesame seeds. pumpkin seeds and throw in just a little amount of stevia I get from my garden - not necessarily the same every time. I've heard that too many nuts can make you put on weight, but it doesn't work for me. I have trouble putting on weight so I started eating ground nuts and seeds to put on weight - I've never seen a change But I now have a taste for all these nuts - I love them. I guess I'm lucky? I can eat alot and not put on weight. I'm a 63 year old male and weigh around 135 lb naked. Plus, I workout 6 times a week and use the elliptical machine 5 days a week. I'm small but very strong for my size. Basically I'm bone and muscle - very low fat. My wife says that I have way too much energy all the time (especially for my age) but she's comparing me to the normal population. It's so sad to see people continuously hurt themselves. Here is a prime example of how people think: If you were in a friends house, had a big holiday meal and offered to do the dishes, what would the host say to you if they saw you pouring all the warm and hot leftover fat and grease down the kitchen sink - they'd explode! They'd get very upset because you could be plugging up their drains in the house. But, remember, the fat and grease that you just poured down the kitchen sink drain is the very same fat and grease that everyone just finished pouring down their own drains (mouths). They care more about plugging the kitchen drain than they do about plugging up their own arteries. I just don't get it... Again I say, it's so sad...

    • @azsunburns
      @azsunburns 7 หลายเดือนก่อน +21

      Plant based whole food diet kept my obese mother obese. It wasn't until she went back to butter, organic beef, chicken & a sprinkling of low carb veggies did she finally lost 150lb.

    • @docbegone1716
      @docbegone1716 7 หลายเดือนก่อน +9

      How one could gain weight by eliminating all processed oils, fats and sugars from their diets is beyond me. I believe that your mother was not strictly eating WFPB. She was probably eating the "vegan" diet that included processed foods that contain huge amounts of hidden fats, oils, sugars and chemicals. Most bags of chips that you can buy at the local corner store are vegan, but they contain 17 percent calories from oil and fat - just look at the grease on your fingers after eating only a few. People on any diet can lose weight if they restrict calories, but are they getting the necessary calories and nutrients from the food that they are eating. Yes, people can lose weight by eating animals but they are slowly blocking their veins, arteries and capillaries with fat - fat they will cause many many health issues down the road. There are many ways to lose weight - cancer chemo drugs are very good at it. Losing weight does not necessarily equal gaining health. One should concern themselves with eating the correct food for our species, and losing weight will be one of the many healthy side affects derived from eating correctly. Please have you mother reconsider her decision and have her eat strictly whole plant based foods.

    • @azsunburns
      @azsunburns 7 หลายเดือนก่อน +9

      @@docbegone1716 because for 75 years the USDA had been advocating grains, potatoes, corn, etc. My mother stayed fat on her beloved shredded wheat, oatmeal with banana, steamed veggies, an almost fat free chicken breast, etc.
      The woman never brought sugary cereals inside the house. We didn't have white bread. She didn't buy Hostess, etc. I was raised from a very young age to read labels because she didn't eat pork. She stayed fat on the food pyramid = plant based & she preferred whole foods, yet that didn't help.
      One should NOT remove all fats from one's diet. Our entire endocrine / hormonal system relies on them.
      Bedridden, I was able to get my mother from above 350 down to just over 200 on quality meats, butter, her beloved coffee & low carb veggies. Humans did not develop on plant based diets.

    • @irfansohail1977
      @irfansohail1977 7 หลายเดือนก่อน +5

      ​@azsunburns I thought plant based diet is low fat and low cal?

  • @kostar500
    @kostar500 6 หลายเดือนก่อน

    Only 12% of his studies are diabetes free after some considerable time lapse. So weight management needs to be an in built habit and not an intervention it seems.

  • @justinsnow3979
    @justinsnow3979 7 หลายเดือนก่อน +2

    Low carb, high protein moderately high fat. Eat real whole food. 👍🏻

    • @trotskyite1
      @trotskyite1 7 หลายเดือนก่อน +2

      I know people who do that and they have t2d

    • @DavidSmith-rz1pc
      @DavidSmith-rz1pc 7 หลายเดือนก่อน +1

      check out Prof Christopher Gardener on how much protein you actually need, quality of protein and what happens to the excess at the end of the day.

    • @potterylady44
      @potterylady44 5 หลายเดือนก่อน

      ​@@trotskyite1exactly

    • @nomadicrecovery1586
      @nomadicrecovery1586 4 หลายเดือนก่อน

      @@trotskyite1they they aren’t actually doing it

  • @GreenishSloth
    @GreenishSloth 6 หลายเดือนก่อน +1

    SO annoying to hear this constant "carb" bashing over and over. There is a huge difference between doughnuts and cake, and beans or flax meal. Taylor doesn't appear to get it, even when specifically prodded. Okinawans of old consumed 60%+ of whole carbs and diabetes incidence was very low. And their cardio-vascular health was great. And they lived longer than pretty much any other population.

    • @nomadicrecovery1586
      @nomadicrecovery1586 4 หลายเดือนก่อน

      To the body there is ZERO difference
      A carb is a carb

    • @GreenishSloth
      @GreenishSloth 4 หลายเดือนก่อน +1

      @@nomadicrecovery1586 Your statement is not true. But if you have any evidence to back it up, please post.

    • @GreenishSloth
      @GreenishSloth 4 หลายเดือนก่อน +1

      @@nomadicrecovery1586 Did you just say that?! It must be your brains on doughnuts. Or bacon? Because it's absolute nonsense.

  • @thewinner3042
    @thewinner3042 6 หลายเดือนก่อน

    bs

  • @doddsalfa
    @doddsalfa 5 หลายเดือนก่อน +1

    The fat you eat is the fat you wear

  • @irfansohail1977
    @irfansohail1977 7 หลายเดือนก่อน

    At 1:22:00 he said getting rid of diabetes but then whole video suggests remission for few years and it will return...so it won't cure the issue just put to sleep for few years ??

    • @clownbackpainrick6581
      @clownbackpainrick6581 4 หลายเดือนก่อน

      It would be nice, when there is a success rate (after 10 years maybe) of 80%.
      But what is the alternative? Is there a better one, that has more than an 11% remission (profen). And I guess the others, who are not in remission do better than the control group.
      A profen (randomized controlled trial) alternative for remssions does not exist. The alternative classic path is: you are put on drugs...

  • @user-jk3zp6mi8d
    @user-jk3zp6mi8d 7 หลายเดือนก่อน +1

    If pancreatic fat overload reduces insulin output, why do we measure insulin resistance by looking for elevated fasting insulin levels?

    • @TheProofWithSimonHill
      @TheProofWithSimonHill  7 หลายเดือนก่อน +3

      In the early stages of diabetes the Pancreas compensates by releasing more insulin. The output drops after years of compensation.