Bruce Ames on Triage Theory, Longevity Vitamins & Micronutrients
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- เผยแพร่เมื่อ 13 มิ.ย. 2024
- In this video Dr. Rhonda Patrick interviews Dr. Bruce Ames about his triage theory, which he proposes that the body has developed a rationing response to shortages of micronutrients (vitamins and minerals) throughout evolution. When cells run out of a vitamin or mineral, that scarce micronutrient is allotted to proteins (in the body) essential for short-term survival. Proteins needed for long-term health, including those that protect DNA, lose out and become disabled and lead to diseases of aging. In addition they discuss how RDAs are chosen and what Bruce calls “longevity vitamins” which he calls a class of nutrients that exist mostly to prevent degenerative diseases of aging in addition to essential vitamins and minerals.
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Chapters
00:00:00 - Introduction
00:02:36 - Triage theory
00:15:21 - Vitamin K
00:21:07 - RDA vs RDI vs EAR
00:31:45 - Vitamin D
00:36:28 - "Enough is enough"
00:41:42 - Diet vs supplements
#Triagetheory #supplements #diet #longevity - วิทยาศาสตร์และเทคโนโลยี
He's 86 and dedicating his time to research and share these vital information for the benefit of all. Thank you Dr.Ames, and to you to Dr.Patrick. :)
I loved this video. You can see the respect that Dr. Patrick has for Dr. Ames and he for her. What a blessing for Dr. Patrick to have worked beside him and undoubtedly learned from his years of experience and wisdom. And what a blessing for him to have someone so brilliant to working beside him to certainly continue his research! And we are all blessed for having them in our world!
syENERGY
Dr. Ames literally is out of this world; ethereal; brilliant.
This dude is 92 now and looks healthier than he did in this video!
Source?
Carnivore
He's 94 now 😮
I hope he lives long enough to receive a Nobel prize..
Dr Joel Wallach has been at the head of nutrition research long before this guy,and he was a Nobel prize nominee look him up.
What an eloquent man. Natural teacher. And a fountain of knowledge, thought and connectivity in investigative nature. Thank you so much for your time and efforts.
I have watched this video multiple times - Dr Ames is a gift. Thank you Rhonda!
Back in the 90s, my prof described a “hierarchy of need” related to health and nutrition. The most important organs get first dibs on vital nutrients. His wording was different, but he was describing this triage theory, really.
Bruce N Ames PH.D Scientist, Jedi Master.. Love it...
You forgot the part where Rhonda is the padawan ;-)
Triage theory transformed my thinking and got me interested in vitamins and minerals again. Thank you, Bruce Ames.
Here's a few great quotes from the video...
4:18 - “Folic acid deficiency does the same thing as radiation.” - Bruce
10:35 - “When you get a little low on any vitamin or mineral, it’s to nature’s benefit to ration it. Where would you expect it to ration it if you don’t have enough selenium, or Vitamin K, or magnesium? Well, it’s going to put it into those proteins that are essential for survival, because what nature wants you to do: survive and reproduce. Thats strong selection. Living to ninety? Nature doesn’t really care about about that, because you’re past your reproductive age.” - Bruce (on insidious micronutrient deficiency causing aging or “The Triage Theory”)
14:37 - “For example, in Vitamin K, the clotting proteins get it first… and only after they’re satisfied do you prevent calcification of the arteries, or prevent cancer, or prevent bone fractures. It’s all insidious damage that you get that’s a long term consequence. In fact, we call these the diseases of aging.” - Bruce (on The Triage Theory in selenium and vitamin k dependent proteins)
22:13 - “Over the years we’ve discovered these 15 vitamins, and 15 essential minerals… but it’s all based on some disease that shows up or people dying.” - Bruce (on longevity vitamins and the trouble with using only acute symptoms for defining essential nutrients)
23:20 - “I have an italian wife who feeds me a wonderful diet. She kept on nagging me that I should get more exercise. One day I said: when I feel like exercise I run my experiments, I skip controls, and I jumps to conclusions! I liked that joke so much I must have told her it fifty times and one day she said, "I’ve heard enough of that joke, I’m getting you a personal trainer!” So now I go and work out twice a week.“ - Bruce (on his exercise habits)
24:24 - “The EAR (estimated average requirement) is actually set two standard deviations lower than the RDA and people still aren’t even meeting that.” - Rhonda
25:25 - “What you want to know is… does it shorten your life? You can do those kinds of questions in mice, but those are expensive to do and no one’s been really doing them.” - Bruce (on studying deviations from optimal micronutrient intake)
31:05 - “The obese are eating the worst diet in the country if you define worse as ratio of calories to essential micronutrients. They’re just eating empty calories.” - Bruce
36:46 - “The docs are all used to randomized double-blind clinical trials, which makes a lot of sense because if you test a drug in people, no one has it to start with! But… applying it mindlessly to nutrition is stupid, because if 90% of the population has enough of Vitamin X and 10% are really deficient, you want to test it on that 10% otherwise you’ll never see anything because you’re diluting [your results] with the 90% that have enough.” - Bruce (on the problem of randomized double-blind clinical trials in nutrition)
38:12 - “Medicine has sort of abdicated [their responsibility]: most physicians know nothing about nutrition. They don’t get any training in medical school… maybe an hour or two lecture. […] I think prevention is going to involve different people. It’s going to involve people who know some nutrition and can figure out mechanism. The analytical methods are coming fast so that you’ll be able to put your finger in a machine and it will send the results to your iPhone.” - Bruce
42:05 - “If I don’t eat veggies with a meal, I feel deprived.” - Bruce
42:15 - “I think we all should try and eat a good diet. It’s actually a wonderful to eat a good diet, because you’re eating all of these different kinds of foods… and they all taste good, and when you get used to it, you feel better!” - Bruce
(Originally shared at foundmyfitness.com/news/s/hopjwr/)
At 4:18 "Folic acid *deficiency* does the same thing as radiation." Thanks for the video! :)
Fabian Popa You're welcome, and thanks for the correction!
FoundMyFitness Bruce is great, I worked for him producing and filming his juevon nutricutical infomercial. I still use his vitamins today and have more energy then in my teens. I started following his advice in my mid 20s and now in my mid 30s and have learned a lot from this wise man.
FoundMyFitness his Oakland office looks much like it did when I was in there 8 years back.lol
rhonda would you say that fermenting vegtables, etc destroys some of the more delicate vitamins?
Thank you dr. Rhonda Patrick and dr. Bruce Ames you guys are the best! Geniuses at work showing love!
This man is SUCH a legend, GO BRUCE!! Thank you for all you do.
You two have just further developed my interest in pursuing a career in nutrition. With my biochemistry background I can totally understand how these scarce nutrients could become such a huge problem. Nutrition is soo fascinating and yet such a huge necessity. One can't help but to research how much of what and when and where it's needed!
Cara Cee I agree :) your awesome friend
Save the world girl !!
A mate of mine was absolutely amazing with chinese medicine, accupuncture, osteopathy... wow you could go to him for anything. ALL NATURAL ♥️♥️♥️
He's since passed, the best Dr I've ever been to. People used to travel hrs to see him, Olympians loved him. Its healthiest ive ever felt in my life. He always said to me, there is always an alternative to pharmaceuticals with Chinese herbs.
He also told me before he died there was a link with antibiotics to breast cancer
Always best to stick with natural sources
Good luck! All the best
I hope you can cure some major diseases. 🙏👍
Clearly, the force is with him. And Dr. Rhonda.
Thank you Rhonda and Dr. Ames. Your focus on prevention is so important yet so ignored in this country.
What a great treasure this man is ! Thank You Dr Patrick! I am thrilled to have found you both!!
What a treat it is to see an interview with the infamous Bruce Ames! Thank you! If our educational system were better this video would have millions of hits!
Infamous? Why?
@@evensteve284 also wondering
This is my first exposure to the great man that is Dr. Bruce Ames. What a wonderful human being, it must be such a pleasure to have him as a mentor. Thanks Rhonda for all the amazing knowledge you have to share with us. I walked away from this video feeling enlightened.
This month I watched all of your Joe Rogan episodes and learned about Bruce Ames. Thank you for introducing this wonderful man!
1000 thankyous for bringing the man who changed the way I look at nutrition. I asked you for this weeks ago and you delivered. Please tell Dr. Ames thank you.
Dr. Bruce Ames, you have earned our respect both by your age and your significant contribution to all. You are indeed a man of high distinction and deserving of such.
Dr Ames, love this talk and your dedication to science and health. Dr. Patrick you are a super star and I look forward to every video.
I have so much respect and admiration for you and your work
Our Canadian Government stopped paying for the Vitamin D test. They said its not a vitamin (hormone) of importance. Never pays to follow the nutritional advise of your government. I usually do the opposite. (They recommend Canola Oil as a healthy oil. I'm sure its because Canada is the largest producer of Canola Oil.)
Allen Miller thanks...I was just about to go get a Vit D test....now I’m shit outta luck....bad enough OHIP supplements bad habits like smoking and sugar eaters....smh
Yes my mantra is whatever your government tells you to do then do the opposite xx
It's poison.
Canola Oil was used as an oil for mechanical machines, they found that it did not kill people. Now marketed foe human use.
It used to be called Rape Sees Oil, and still can be found in commercial peanut butter, sometimes.
Same with the government of United States of America....they recommend carbohydrates and soybean oil
Been taking my vitamins going on 20 years now, never stopping.
An absolutely fascinating interview. Thanks Dr. Bruce and thanks Dr. Rhonda!!
Dr. Rhona and Dr. Ames, can I just take this opportunity to thank you for your work and especially for trying to distil the science for the lay person like me. You are on the cusp of a revolution in people taking their health into their own hands, and you taking this precious time to make videos, do podcasts with others etc is a vital part in getting this information out there. I'll pass on the word as best I can. Hello from Ireland and thank you again. The world is such a better place for people like you. Regards, Grainne
I'm impressed with Dr Ames contributions to science and his sharp mind at 86. This was a great interview too
I LOVED the interview! It was fun to listen as it reminded me of how lucky I was to have Dr. Ames explain his assay in my nutrition class and then to perform assays using common toxins found in sprouts, mycotoxins in corn. The conversations we had with him were tremendous and gave us insight into how food safety and research is done. I thoroughly enjoyed this 30 year reunion! :)
Amazing interview!
People just clear your heads of what ever you think you know and do what Rhonda does.
Awesome!!
Fantastic Interview ....I hope Dr. Bruce Ames will live long and happy ... with good food . Both of you are hero's .
Congratulations ! Yesterday 12/16 was your birthday, happiness and lots of light on your journey.
What a privilege and an honour to work in Ames lab, Rhonda. I had no idea.
This is a lovely video. Easy to follow. Rhonda “lives” Newtons words: I can see what I can see, because I’m standing on the shoulders of giants”
"Wow", how is it that this man's work hasn't been trumpeted in the media around the world, for the last 30+ years. Fantastic, Thank you for "another" Great Video.
What a sharp 86 yo!!
Dr Patrick, it seems it would be interesting if you give a chance to your guest to say: “thanks for having me”. So, if I may suggest, after your praises for the interviewed presenting his/er curriculum, please consider saying hello to him/er prior to tossing him/er a question or hint to start. I am very sure you - behind the scenes- say hello and thanks to all your very amazing guests, but viewers need to see that in front of the camera. I take this opportunity to say how great I consider all your videos. I appreciate your precision and clearness exposing matters I am not familiar with, and most
importantly, the quality of the works and findings you bring out to the public.
Fantastic! What a brilliant man. Truly amazing work sir. Triage theory is spot on!
peeness mcgoo I totally agree!
@@FoundMyFitness Fascinating interview ! His theory however does not explain why Okinawans on a traditional diet had severe deficiencies in D , B2 and B12 and were still being studied for their remarkable longevity.
Thank you both for this amazing interview. It inspired me a lot :)
Powerful Rhonda Patrick!!!!!
Skylar Qwerty chances are that you watched at least 1 JRE show... ;-)
Fantastic interview with two lucid experts - I took a lot out of it.
Also laughed out loud at Dr. Patrick's reaction to the Mae West quote.
Bruce and Rhonda, thank you both for all you do and I hope you keep doing it for a long time.
I have not listened to this video yet. Just the first 2 mins. But I am so excited that this guy is alive and well enough to keep going in his field. I wish to meet one of these greats one of these days.
This is really awesome.
Very well done.
Thank you both for the work you do and for sharing it.
So much mutual respect shown in this interview.
Ein wunderbarer Mann. Tolles Interview.
Danke dafür
Many thanks for sharing this Dr. Rhonda and Dr. Bruce
I didn't make the connection that this was the SAME GUY that invented the Ames test, until you mentioned it. That's crazy cool!
jhdgkjsh He is amazing! I am so fortunate to be able to work with him everyday!
Wow what a great interview. I feel like a sponge trying to soak all this up. Thanks much for your efforts Rhonda. Much respect to Dr Ames too. Getting old but mind is still sharp. Keep hanging in there!
"What I postulated, just an idea that came to my head. When you get a little low on any vitamin or mineral, its in natures benefit to ration it. The way it rations it, where would you expect if you didn't have enough selenium, magnesium, or whatever. Whats nature going to do....it's going to put it into those proteins that are essential for survival. That is what nature wants you to do is survive and reproduce. Thats strong selection."- Bruce Ames That is a great piece...hope I quoted him correctly there, I was typing as fast as I could!
Thank you to both of you, for your work and information.
Awesome interview!
Can always rely on your videos for great information
Thank you so much Dr. Ames and Dr. Patrick for uploading this very insightful discussion on You Tube. Rhonda's questions were always right on target in eliciting the most valuable biochemical principles from Dr. Ames' profound understanding & experience in this field. As a biological scientist I've been frustrated by the disconnect in nutrition & biochemical outcomes versus overall human health that is presented by people with little research knowledge of the field. Thanks again because you both have vastly enriched my approach to nutrition.
Excellent!! Love this man and you Rhonda! Thank you for your important work!
I learned so so much from you two talking, Dr. Rhonda! This is really a great message to everyone on how we should look at nutrition - our deep relationship with foods i.e. plants. Thank you so much :)
eat your HONEY😋...FUNgi, Moringa, Turmeric, Alfalfa🍒
Is this the guy who made the Ames test? Wait, never mind, you just said it. That's awesome you get to work with people like this!
Awesome interview. This is music to my ears. Very inspiring.
Awesome!!! I enjoyed this very much! He was a joy to listen to!
Win Win WIN...
I cured my vision issues in my late 20s when I took lutein/zeaxanthin and removed as many glutamate compounds (glutamic acid being okay). I realized alter that it was huge for me to get more morning sun (for UVA) and eliminated the electromagnetic fields away from my body and brain. The poor are eating a TON of glutamates, and if they are already excitotoxic with a lowered redox, it's just aggravating that lowered health even more. This all ties back to the mitochondria craving calcium, with calcium effluxing from some cells into other cells to compensate for the damage. More hydration folks... more sunlight for making a better charge separation in the water for more energy harvesting into the ECT with the mitochondria. Gerald Pollack is gonna get a Nobel prize someday.
An excellent video. Great conversation! I've actually taken a lot of your vitamin and nutrition advice Dr. Patrick. Thanks so much!
Awesome interview!! Explained so much so clearly!!! Thank you!!💖😀
Fantastic interview. Your work and field is so intriguing. What an exciting life.
Wonderful interview, thank you Rhonda.
Great video. Hope to see more. And, thanks for posting it.
Love how he corrects super smart Ronda Patrick on scurvy (not rickets)
Of course at his age he may have actually seen those deficiency diseases where most of us have not.
He's sharp to hang w her.
I'm thinking he's on to something.
Looks like he's 94 now and still alive!
Amazing ,thank you for sharing all this info!
This was so wonderful! Loved it!
Wow awesome interview thank you both!
Thank you Dr. Patrick for explaining the K1 relationship with the calcification of aa. Fascinating!
An additional thing to what Bruce talks about at 39:17 would be the ability to quickly analyze the nutrients in the food that is about to be eaten. Being able to put a piece of food in a device and have it quickly spit out all the nutrients and then combine that with the blood drop test indicating what is required. Once we get to that point then perhaps accidents will be only reason people don't live to their full potential.
The information on folate deficiency is so valuable. I have the MTHR mutation and take extra folate. But I understand that too much methylation can also cause problems, like cancer. Dr Rhonda, I wish you could talk about this issue because I never see the explanation or studies anywhere of how much folate is enough but not too much.
Thanks Rhonda, Always bring wonderful knowlenge :)
Nutritional Sciences student checking in, defining certain terms in the lower third was a great touch for the non-biochemically acclimated. Great interview! :)
Dr Patrick, I love your videos! You have the rare ability to share complex information in a way that makes it intelligible to the layperson without drumming things down. The same is true of Dr Ames. Thank you for your work!
Thanks to
BRUCE "ARNES" A
HOPE HE & HIS FORMIDABLE CONTRIBUTIONS, TO MEDICAL FIELD, NUTRITION , INSPIRE , ALL PEOPLE TO TAKE NUTRITION SERIOUSLY,
Bruce Ames
Great video. Keep up the great work.
amazing discussion... thanks so much!
All this content is a real life improvement information. Many thanks for sharing it.
Amazing Dr. Bruce as 86, great scientist still transforms the medicine!
I love that she added "most cited" at the beginning.
Brilliant interview!!!
These two great scientists are so modest !
Thanks for all your work, ;)
One of the best “elevator” summaries of how nature trades long-term health for short-term health as an explanation for senescence. Thank you!
This has so expanded my ideas outside of the regular box of “consensus biology” especially as regards to vitamins (or should I say the subset of compounds officially designated as such) that I will modify my undergraduate teaching of these concepts.
This was wildly informative and interesting
45:51 / 46:58
Many thanks Rhonda and Bruce ! Cheers
Dr.patrick you are so great for bringing Dr. AMES here
I always wished to see him the one who devised the Ames test
so thank you
More over your channel is so great I just stumbled upon it
Thank you again
Your beauty outshined this brilliant man.
Love him and this topic.
Fab, Thank you both.
One of the greats. Up there with Linus Pauling.
I just love Dr. Ames. I've followed his information for a long time.
For vitamins and minerals I wrap a bite of organic chicken liver in nori seaweed, wet the seaweed to make it slippery and easy to swallow, thats my version of a cheap potent vitamin pill. Admittedly it's a big pill to swallow so dehydrating the liver first maybe a good idea (if it doesn't harm the nutrients).
Excellent interview.
Wow, Bruce is awesome. Great Video.
Thank you
I love this guy! He's cool as all get out and the content of this video is terrific. Cant say enough. Thanks!!
Thank you!! I dont know if you read these... but I would love to know the tests I should ask the doctor for in order to tailor my diet. I am loving all of your work on youtube and have to pause the video every 10 minutes or so to research a new word I have never heard of haha. Love it. I love the little definition pop ups too. Would love more like a picture for the natto mentioned and perhaps a more direct advice on exactly which suppliments you reccomend. So far (with your vids) I am up to PQQ, D3, B complex, hydrosuminsumin collagen, salmon roe!. But in your podcast w joe rogan you mentioned that getting your biomarkers..marked.. can let you know if crusiferous vegetables or a keto diet etc. (Not into it) would work for you or not. Would love more videos on clarifying what steps a layperson can take to fine tune thier diet and excersize from really basic finances and educational background, because as you said for each opinion there is an opposite and it is so difficult to figure out the most recent/correct info. Fangirling hard excuse me.
Another fantastic vid from DR RP. She is cool.😎👍