My NMN Update | Recent Experiences
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- เผยแพร่เมื่อ 1 พ.ย. 2023
- I've taken a break from NMN and NR, but recently decided to start taking them again. And, in the video I will share with you what I've recently experienced.
Backstory: I began taking NAD+ boosting supplements in 2019, but it wasn't until Oct. of 2020 that I began taking them consistently. As of sometime in 2022, I took a big break.
Disclosure: I work for Renue By Science and I share that in this video. I started taking supplements before I got hired with them. They found me from my videos on this. With that said, this video and all of the content on my site and on my TH-cam channel are my own.
For anyone wondering, I am 41. I get asked my age a lot in videos like this. Although I like taking certain supplements at different times in my life, I still believe that diet & lifestyle are most important!
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PRODUCTS⤵
I am an affiliate for some of the products mentioned here & will receive small commissions if you make a purchase.
Thorne Resveracel amzn.to/3miUQQd (you can probably get it cheaper on their website if you use a code: s.thorne.com/9a5Rk) *
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MY OTHER VIDEOS RELATED TO LONGEVITY⤵
-My experience taking NR for 9 months: • NR & NMN for Anti-Agin...
-My First Biological Age Test Video from 2020: • MyDNAge Blood Test & S...
-My 2nd Biological Age Test Video from 2021: • Biological Age Testing...
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SUPPLEMENTATION AND TEST RESULTS⤵
October 2019 - I started taking my first NAD+ Booster, NR
August 2020 - I started taking NMN
June 2021 - First tested my NAD+ levels to get a baseline level: 19.1
March 2022 - New washout period & new baseline level: 25.8
May 2022 - Took NAD+ Complete 2 capsules/day for 2 months: 44
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MY FAVORITE PRODUCTS ON AMAZON⤵
lifeanddiy.com/AmazonFavs
* These are my favorite products and supplements! I am an affiliate for Amazon and earn small commissions if you purchase anything through here.
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Disclaimer: The Video Content has been made available for informational and educational purposes only. The video creator does not make any representation or warranties with respect to the accuracy, applicability, fitness, or completeness of the Video Content.
The Video Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.
The video creator hereby disclaims any and all liability to any party for any direct, indirect, implied, punitive, special, incidental or other consequential damages arising directly or indirectly from any use of the Video Content, which is provided as is, and without warranties.
Thanks for the update 🙏 I hope you and your family can continue to improve your health 👍
Thank you! 🙏
Thank you Holly for your update! I have been using NR and NMN for years as well (no long breaks though). I do want to mention, I took the ReservaCell as well and it is the Resveratrol that makes you hungry - because it mimickes fasting in your body, from what I heard. I’m currently taking 250mg of NMN, every other day with 125mg of Resveratrol from Alive by Science. The other days (when I work out) I take 2 capsules of Designs for Health - ArthroSoothe- which has 250mg of Nicinamide. My joints and body feel good. And it’s not too much I feel. I’m about your size and also sensitive to most things. So I’m always experimenting with dosage:)
Always appreciate your prospective on you health journey. I also been struggling with sleep for more than a year.
Thank you! I appreciate that. I am so sorry about your sleep issues over the last year. I really hope it improves. It is such a struggle. I actually like waking up early and relaxing, then actually working early but not this early at 1 AM or 3 AM. Hopefully we can both fix these issues soon.
Hi Holly...funnily enough that's my stepdaughter's name too, and I happen to get the majority of my supplements (sent to NZ) from the company you work for which honestly is also a coincidence.
I started taking 4 of their liposomal supplements - NMN, Resveratrol, Defender and Activator - plus garlic and Neprinol (a blend of systemic and protease enzymes with cofactors). Almost immediately I found a boost in my energy and wellbeing and that has not subsided. BTW, I'm male, 55 and live a mix of IT work and farm life, so high energy is vital.
I appreciate your personal insights and always look forward to seeing your videos come up on my notifications. Thank you for sharing and I wish you well.
Hi Dave and thanks for the great comment! I am so happy to hear that you're doing well with those supplements. It sounds like you have an interesting life with the farm and IT work. I love that thanks to technology (for example: Starlink) someone can have a farm life or live in a super remote area, yet still do work online. It's great! And, your step-daughter has a great name! :) When I was a kid, my next door neighbor was the same age as me and was my best friend - her name was Holly. I only lived there for a few years though and moved away. Ever since then, I've never known or met another person with my name. So I am not sure how common it is anymore. Besides that, please let me know if there's ever a topic you want me to do a video on! 🙏
Really appreciate your videos. Your video about beauty products and microphone needling really helped me. I applied them and make myself look like 10 years younger and my confidence about myself is back and high♥️
Whatever you're doing it's working you look great!
Thank you, Charlie! 🙏
Thanks a lot for sharing. Love this type of videos from you.
Thank you so much! I will try to do more like this.
Thank you for the update i just started taking NMN ❤ it makes me feel better and energized 😊
That is great to hear!
Love your stuff:) You single-handedly introduced me to NMN. And like you said, I suddenly feel alive in a weird normal kind of way. Just finished another DIY medical micro needling session - Face and neck looks like shredded bacon;) I don't know … just thought I'd let you know you're really cool in my book. Only a few friends have the status of being really cool. Thanks for everything. Love your videos.
Wow, thank you for such an awesome comment! That's amazing to hear about feeling alive from NMN. I have felt that from one other supplement, and it's called Shilajit. Not all versions are the real deal or super pure, so I am researching a good brand. I'll do a video on it in the future. I hope your skin heals well from the microneedling! And, have an amazing start to 2024!
@@LifeDIY Man, you just sent me down another rabbit hole! Ha ha Shilajit. Here goes another six months of researching something new! I already have limited time on all the other rabbit holes I'm involved in lol. I'm a guy… And what am I into? Micro needling face and scalp, face yoga, yoga, exercise, carnivore diet - 95%… It's insanity;) Ha! ...On one of your recent videos you spoke of wanting to get closer to God. It's pretty easy, I speak to him aloud as I would speak to any one of my awesome buddies - Unless there are other people around, that would be weird… But then again, would it? I talk to him as if he's in the room with me. If I see something cool in a movie I'm watchin' I mention it aloud as if he's chillin' on the couch right beside me. He's with us always. I've also had a guardian angel my entire life… He (or she - Idk) likes to play tricks on me, flicking screws off of my hands when I'm in the middle of a tough project, stuff like that. I speak with God as if he's my best buddy 'cause he is:) Peace out, H.
Hi Holly, great video.
I had disrupted sleep every time I upped my NMN dose, it usually sorted itself out after 3 to 5 days.
Also, if I took NMN after 2 to 3pm I also had disrupted sleep, I now take just after I wake, so before 8am; so far, no problems (it's been over 6 months since I made that change) and great sleep.
Thank you Vince for sharing this! My disrupted sleep started long before the NMN, and weirdly I have had a tiny bit better sleep since restarting the NMN now. I'll still be careful to take it earlier in the day though.
Interesting video Holly! I started taking NMN & NR a few weeks ago and initially I thought it wasn't making a difference to me. However, starting this week I've noticed that my sleep has improved a whole lot and the only thing that I've changed in my life/diet etc is the supplementation. I track my sleep with an Oura ring and I've had gradual improvement in my deep sleep as well as a big improvement in my HRV. My HRV has been really low for months, so somehow I think the NMN/NR is helping my body better deal with stress. I'll keep taking it and see if that improvement continues!
That is awesome to hear, Rod! About how much are you taking? I know long ago when I used to take it consistently, that's also when my sleep was better, and I had such a high amount of deep sleep (also tracking it on my Oura ring). But, I am not sure if it was related to the NMN at all. I just thought I always had very high amounts of deep sleep. Since I just started taking the NMN again, as of this week my HRV has continually dropped little by little, now at 22. I'm happy to hear yours has improved though. I just noticed that my HRV was much higher all through the summer months. I'm going to keep taking this for a while, to see if I have any more improvements too.
I was thinking it help with rem sleep not with nrem sleep 😮😮😮😮
Is dropping in HRV good or bad ?! 👀
Excellent products! Thanks!
Thank you! 💜
What are your thoughts on liposomal nmn? I think you used to have a video on it, but that must have been one of the videos you took down. Thank you for your videos!
I took resveracel for a year and recently my normal nr ran out but i still had some resveracel left and started again. I think it hurts my tendons/muscles or something, i get mild "discomfort" in under thumb area palm muscle and noticed same in feet now last time i restarted. Happens after taking it for a couple of days in a row. I'm not convinced it's good to take quercetin for a prolonged period or it might be the resveratrol not sure?
There she is...What a stunner :)
Hey love your videos can you do house renovation videos or general day in a life ones. Love all your content.
Sure! Thanks for the reminder as I was recently editing a renovation video. I would love to do that!
Thank you for the update. Do you take TMG with your NMN?
Yes, I just started taking it yesterday, just in case. I use the one by Life Extension.
Holly , I think I made a similar comment to you before but I really wish you would consider taking organic psyllium husk for overall health . I know you mentioned potential kidney issues so I suggest that versus beans but one very possible reason you can’t sleep or stay asleep is too much adrenaline production going on. So it’s important to rid your body of excess hormones , not just adrenaline but excess estrogen and other hormones that are never able to leave the body unless they are able to bind to something in the GI tract to prevent the reabsorption of the the bile in which the hormones will be floating in when it gets to the terminal part of the ileum of the small colon. Soluble fiber is that binder or trap so to speak .The body reabsorbs about 95% of the bile and unfortunately hormones never get broken down in the liver so they wreak havoc along the epithelial cells that line the GI tract and trigger all kinds of chemical reactions , many of them negative . Hormones are also what this one nutritionist /biochemist calls nuclear receptors , meaning they are so tiny that they can zip through the nuclear plasma and get access to the DNA where normally nothing can penetrate . And depending on where along the DNA it hits, it can damage and mutate it hence causing cancer if it hits the part of the DNA that is the DNA repair sequences .
I highly encourage you to spend some time listening /watching to this lady . Continually ridding your body of excess hormones, specifically adrenaline , might enable you to fall asleep and stay asleep . Please give this lady a listen , she’s not your garden variety nutritionist . karen hurd.
On another subject , I need your advice Holly. I’ve been noticing more pores on my face and while I don’t like them , the itching of my pores is driving me mad. I wash my face carefully and moisturize it . I don’t want to use hydrocortisone like someone suggested because that probably wouldn’t be safe long term. Do you think something like the Molecules toner that you use before micrineedling would be useful to implement in my daily routine ? It’s so weird how pores can be itchy . And sometimes I scratch them hard and then notice wrinkle like lines where I scratched it. 😒 advice ? Thanks Holly! I’m 47 .
What do you think of apigenin? Have you tried it?
I've stopped with the precursors. NMN, NAD+ & Resveratrol. Am testing some others and doing regular aging tests.
How's it going with the aging tests and do you mind if I ask which ones you've done? I have the TruAge test recently, but haven't shared it in a video yet. I hope it goes well with the other things you're trying.
@@LifeDIYhave so far tested Tally Health & Nuchido. Will have more data soon.
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Waking up early after sleeping, for me at least happens if I donate a lot and my ferritin level goes down. When I get my ferritin back up again i enjoy my full 8hrs sleep.
I don’t know if you have tried this but the carnivore has removed many issues I’ve had. If not at least look into it, it’s a game changer. Still having issues with waking up early (wide awake immediately) I know many people with sleep problems lately.
Thank you! Did your sleep problems start after you were doing carnivore for a while? I have been doing carnivore since June, though I'm trying to branch out and eat more ketovore, but having some problems. Some days I eat pure carnivore and other days I eat some carbs lately. The reason I'm trying to do that is because my sleep is killing me and it's been bad (waking up at 1 AM or 3 AM) since one month into carnivore. I can't handle it anymore. :) So carnivore has taught me a lot and helped in certain ways, but it's also caused me to have more food intolerances and sleep issues I never had before. I plan to chat about it in an upcoming video. Prior to carnivore, I was already eating very healthy and very low carb, so I experienced so many benefits from that in itself (I'm also dairy and gluten free).
Thanks!
Wow, thank you so much, Charlie. That was an unexpected surprise! 🙏 I appreciate it.
@@LifeDIY you're very welcome!
That was way too kind. Thanks again, Charlie!
It was my pleasure, looking forward to the next video
Привет ) без перерывов нельзя применять долгими курсами. Оптимально месяц через месяц , максимум 2 месяца . При непрерывном приёме NMN Вы истощаете метильные группы , и уже в короткой перспективе ощутите снижение эффекта , или возможно совсем его отсутствие .
RENUE BY SCIENCE на сегодняшний день одна из лучших фирм , особенно их Lipo формы . Они повышают биодоступность , а так как проницаемость стенки кишечника у всех разная , то и второй бонус липосомальной формы - более точное дозирование уже в крови .
Если посчитать экономику , то Lipo формы намного выгоднее .
Я 1,5 года пользуюсь NMN Lipo , приблизительный эффект - около 15% увеличения продуктивности на пробежках . + некоторые улучшения когнитивных функций .
Желаю Успехов в Ваших экспериментах , и хорошего дня !
Thanks for sharing this! I think that is a good approach, to take breaks. I'm glad to hear the liposomal products are working well for you! 🙏
I've heard NMN is illegal, is that true?
I take thorn resveraCel but I doesn’t make me hungry. I take berberine too but it reduces appetite.
I take NMN for age related sleep disorder. It does seem to wake everybody up at about 2-3 AM for about 5 mins feeling ready to go but just lay still and you should drift off. with that being said my regimen changed when starting berberine (absolute miracle compound) berberine allows you to push through the 2-3 AM without waking but the trade off is a 4:17 wake up time. so bedtime is 8 no big deal. BTW berberine is everything resveratrol was promised to be and way more(SIRT1). Resveratrol is toxic , lessens lean muscle mass I suggest you drop it .
Interesting! Thank you for sharing this. I have been a big fan of Berberine as well and I took it for a long time to help with SIBO. But, I don't need it now as my blood sugar is low enough that if I take Berberine (the last time anyway) I had an issue with very low blood sugar. I feel like it helped me a lot in the past though, but I didn't notice any impact on sleep. How much NMN do you take? And, I am not sure about Resveratrol and with some of these things, there should be more/better research.
When taking berberine you need less NMN than without as it pretty much raises NAD to youthful levels on its own (as well as most endogenous anti oxidants). I take 1 gram upon waking when on berberine and I was taking 2 grams before the berberine and feel like that's enough . probably never coming off berberine 2.4 grams per day with some fasting and 1000 calorie workouts and have not had low blood sugar yet. blood sugar is only 1 of hundreds positive effects of berberine. I have hade tons of complements while taking it . Huge changes in my face 60 days in. I looked in the mirror and WoW I look so different now. @@LifeDIY
I would suggest checking out pterostilbene in place of resveratrol
id recommend getting a whoop device for sleep tracking
Thank you! I have heard good things about the whoop device, but I've been using the Oura ring for ages. I'm not sure which one is said to be more accurate for sleep though.
Are you still taking LDN? If so, how much? Thank you.
I am not currently taking LDN, though I have tried it out here and there in the last 6 months, just to see if I would experience any benefits. I had such drastic improvements when using it many years ago and I am still a huge fan of it. I think that maybe my health is just so much better than it was when I took it years ago, so I may not need it now or may not notice much from it. If someone is struggling with an autoimmune disorder or chronic fatigue (and/or chronic pain) even if something is undiagnosed, many integrative health/functional doctors are prescribing it, just to see if it may help because so many people have benefited from it. If I were to take it again, I'd start at 0.5mg personally. I never did well with any dose above 1.5mg in the past. But, everyone is different!
Your body could still be going through significant metabolic transitions and detoxification processes, Holly, as a result of your transition to carnivore. That could impact your sleep by way of a downstream effect. It's a big shift, you've made, after all.
And you are radically changing your microbiome. Our microbiomes play a significant role in biological processes such as mood, sleep etcetera. It is probably still sorting itself out.
Plus, as the candida component of your microbiome dies, it could release endotoxins into your system, which can be stressful. And if you go into oxalate dumping, that can cause anxiety and impact sleep, it's a common symptom.
All possibilities when you go full-carnivore.
I often think the term "keto flu" acts as a broad umbrella-term for all sorts of biological readjustments that stretch well beyond transitioning from carbs to fat as a primary energy source. People get through it, but it can take a toll. If a few rough nights are the worst you suffer, you have been remarkably lucky.
On a more obvious note, presumably you checked your Magnesium when you had your bloodwork done ...? Low magnesium would 100% screw with sleep. Magnesium L Threonate is good for sleep. Some people mix it with L Theanine and swear by that combo. And I've certainly not heard any reports of it causing sleep paralysis, which is good, because you don't want to wake up with that fat little demon sitting on your chest again, or breathing down the back of your neck. Curse that tricksy goblin. 😃
Great advice, thank you! 🙏 I've tried doing a lot of different things to fix it, but it's not happening yet. I've heard of others talk about this issue too. I am going to see if my cortisol levels are messed up as I have a very comprehensive test I can do. Other than that, I have also tried reaching out to some of these expert doctors on youtube as I'd like to have a consult with someone who has many years experience with keto/carnivore people. But, it's been hard to find someone available. So far my magnesium levels in the blood were normal, but it's possible this could be contributing. I'll keep an eye on it and continue to work on improving that. I can also try to incorporate something like avocado, to help my microbiome and some minerals or electrolytes.
@@LifeDIY Yes, this is definitely going to be about constant experimentation. But then, isn't everything?
There seems to be this notion, nowadays, that we can nail down the perfect human diet for everyone, but I don't think it exists, simply because everyone is different. I fully believe that there are people who heal themselves by going raw vegan, but I equally believe that there are people who heal themselves by going carnivore. Things like genetics, inherited microbiome and blood-type probably play a big role. And maybe we need different things at different times - sometimes we need to detox our bodies of accumulated plant-toxins; sometimes we need to detox our bodies from the toxic byproducts of excessive meat consumption. Our ancestors probably did this more naturally through seasonal eating.
Good luck, Holly. You seem to be very tuned in to your body nowadays, so I'm sure you can crack this. :-)
NMN make your cell work more correct so that means they need more food to work. That is what I think. Not so strange if you think about it.
I find it hard to take only 1 MNM.
How is NMN still for sale? It has been banned by the FDA.
There is an ongoimg court case with the FDA. It is still sold here, exceot on Amazon.
heeeeeey, i am so late to the comment section, lol. i was out for a couple of days, and i have a different account for my mobile and a different one for my computer.
btw, wouldn't nmn be more efficient if we can inject it into the blood stream somehow ?
and yeah.... i had that sort of schedule too at one point, fell asleep around 6 p.m. and woke up around midnight, lol.
anyway, a pleasure seeing you as always🙂 i am going to rest now, i need a lot of it.
Hope you got some rest! It sounds like you're on my messed up sleep schedule. Some people tend to get NAD+ injections since the purpose of taking NMN is to raise NAD+ levels. It's really expensive, but anyone I know of who has had it done has been pretty happy about it and how they feel. I wonder how long that lasts.
@@LifeDIY today i repaired my balcony door, it's a sliding door, weights a ton (around 30 kilograms / 60 lbs) one of those small wheels was broken so i had to replace it) anyway, your schedule doesn't need to be messed up🙂 think of it as ... living on a different time zone setting💃 TA-DA !💁♂ 😆
i mean i like it when i wake up in the middle of the night to make breakfast, lol. the only problem is that... by the time it's 11 a.m. and i should be productive during the day... that's when i feel tired since for me, it's like... evening, lol. (like i said, it's like living on a different time zone setting, lol)
and Holly, i hope you have a great week ahead😇
and even if not, don't worry, such is life i suppose with ups and downs, you know...
I've not experienced hunger from taking NMN, but I do when I take Berberine. For quality sleep and as a longevity supplement, I take several grams of Taurine twice a day which I purchase from a company called Bulk. It helps in the production of melatonin.
The hunger part is for a different supplement, Not NMN-pay attention.
I have tried the same powder - not only as a drink - but a small past under the tongue - and it has almost immediate effect….
@@StyleViewStudio Yes, within 20 minutes!
Does the taurine have any impact on you when you take it? Does it give you energy/make you sleepy? I do have a bag of bulk taurine and will try it if it might help with my sleep. I keep waking up at 2 AM and I cannot fall back asleep.
@@LifeDIY It's excellent for sleep. I take it twice a day, in the morning and evening. Apparently it's one of the few supplements that has been proven to increase lifespan. From the morning, you feel fitter and more energetic, my muscles feel more defined, but Taurine also "Biochemically, taurine activates GABA(A) receptors in a brain region known to regulate sleep, and it is involved in the creation of the "sleep hormone" melatonin in the pineal gland." I always have a good sleep on Taurine and wake up feeling good too.
Someone told me that NMN might not be safe because tests showed the labels were false. Does anyone know about this?
Amazon used to have a lot of sellers who were not legitimate and some of those sellers sold NMN that contained less than advertised amounts, with a few of them being really low. Most reputable sellers (Renue by Science, Do Not Age, Prohealth), they provide test results for each product, so you know what's in it.
Hunger - possibly the result of faster metabolism (younger metabolic rate)
Have you tried methylene blue yet?
I've only used it in some skincare products, but never taken it as a supplement. Have you?
@@LifeDIY yeah. Life-changing for evening out mood and energy. Just 5 drops per day each morning works for me.
@@whatthefunction9140 I've noticed this too with taking MB in the morning. =)
@@whatthefunction9140Which is the brand you use if you don´t mind me asking?
Only take NMN in the morning up to mid afternoon or youll have disturbed sleep
For good regenerative sleep:
500 mg every 3 hours of niacinamide combined with at least one of these:
Melatonin
Vitamin 5HTP
Tryptophan
Glycine
Taurine
Gaba or
Lysine.
I tried NMN for the first time this year, after you shared a great discount code in one of your videos…I think that was one of videos that might’ve disappeared.? I started taking NMN in April, 500mg of a day...Definitely noticed more energy, and it has helped me a lot with the long golf walks & gardening…How much NMN do you take Holly.?
I’m like that with sleep…When I wake up I can’t go back. I have an unhealthy attitude with sleep, where I think it’s a waste of time, and that I could be doing something better. I know it’s meant to be one of the 3 main things we should get right for a healthy life, so it is worth working on getting enough sleep. I don't know, but maybe it's easier to get more sleep in winter?
Do you update discount codes for NMN on your site, Holly..?
Most likely you don’t need an NMN because you’re still very young, and there is a growth hormone that does its job beautifully… To restore tissues, and everything else…
Thank you! I don't think I really need it much right now. But, it really helped me in the past! I had pretty low NAD+ levels when I first tested years back and when I first started taking these supplements. I should re-test and see how my levels are now. I bet they'd be a lot higher.
… waking up during your sleep cycle is related to a cortisol issue … obviously I don’t know you and what is typical for your character … but you do appear to be very low energy and flat right now … have you tried some Benfotiamine ? It has helped with my sleep disruption patterns …
I used to take B1 and never noticed anything from it but I could try it again. And, if it's true that cortisol is related to my issue, I will find out. I have a very comprehensive test to do this coming week (Dutch Complete) and I was going to wait until my sleep was normalized to do the test, but instead I'll do it while I'm having these issues and see what it says about my cortisol levels. I will share that in a video in a few weeks hopefully.
@@LifeDIY … apparently the Benfotiamine is superior in results compared to the natural B1 … it’s one of the few exceptions …
You look like you are in your early 30s, so you must be doing something right.
Thanks!