How does the presynaptic cell behave when refilling the vesicle with neurotransmitters? 1. Does each cell modulate the presence of all neurotransmitters over time? 2. Or, does each cell release only 1 type of neurotransmitter (while up/downregulating the density)? 3. Or, does each cell release a subset of neurotransmitters (modulating their densities independently)? 4. Or, does each cell release a subset of neurotransmitters (modulating their densities synchronously)?
Thank you for the video, do you know what prevents synaptic vesicles from touching one another? In the first image of your video the SVs appear to be separated by lines, what are those?
The calcium is responsible for the fusion and forming complex with t-snares or the calcium is responsible for immobilizing the vesicles by interaction with synapsin and releasing vesicles from cytoskeleton of cell . Is calcium responsible for both or is one of them wrong
for the last 10 years ive come back to relearn this stuff on snares and it seems like all the names and mechanisms keep changing. maybe my memory is getting bad or maybe things are changing that quickly. i personally wonder about the influence of CART neuropeptide and this whole vesicle packing (VMAT) and docking/release mechanism. maybe I should keep my eye on that too. really hard to find good explanations on CART still... interesting how it seems to be part of the link between amphetamine/cocaine use and loosing ur marbles later in life... also wonder about parkinsons and huntingtons. appearently like 10% of everyone has the "huntington's" trinuc. repeat and every generation it grows a little bit longer until it eventually starts showing up. we will probably start to learn less about these diseases as gene/RNAi therapy starts being more mainstream.
The animation helps simplifly things by a considerable amount for me. Thank you very much.
This was REALLY helpful! Thank you so so much!
Thank you very much for this!!
Really helped me understand my coursework thanks :)
Nice video! It's really helpful!
thank you so much this helped so much ❤
How does the presynaptic cell behave when refilling the vesicle with neurotransmitters?
1. Does each cell modulate the presence of all neurotransmitters over time?
2. Or, does each cell release only 1 type of neurotransmitter (while up/downregulating the density)?
3. Or, does each cell release a subset of neurotransmitters (modulating their densities independently)?
4. Or, does each cell release a subset of neurotransmitters (modulating their densities synchronously)?
Amazing
Great video thanks
Thank you for the video, do you know what prevents synaptic vesicles from touching one another? In the first image of your video the SVs appear to be separated by lines, what are those?
The calcium is responsible for the fusion and forming complex with t-snares or the calcium is responsible for immobilizing the vesicles by interaction with synapsin and releasing vesicles from cytoskeleton of cell . Is calcium responsible for both or is one of them wrong
for the last 10 years ive come back to relearn this stuff on snares and it seems like all the names and mechanisms keep changing. maybe my memory is getting bad or maybe things are changing that quickly.
i personally wonder about the influence of CART neuropeptide and this whole vesicle packing (VMAT) and docking/release mechanism. maybe I should keep my eye on that too.
really hard to find good explanations on CART still... interesting how it seems to be part of the link between amphetamine/cocaine use and loosing ur marbles later in life... also wonder about parkinsons and huntingtons. appearently like 10% of everyone has the "huntington's" trinuc. repeat and every generation it grows a little bit longer until it eventually starts showing up.
we will probably start to learn less about these diseases as gene/RNAi therapy starts being more mainstream.
🙏🙏🙏
🙏♥️
Excellent video
🙏🙏🙏🙏🙏♥️
nice video :)