DNA Replication in Prokaryotes | Initiation

[@Emilia-we2dc]

Literally the BEST video on this subject. Summarized everything that was in the textbook way more visually. Thank you!!!!

[@hussainbiology]

thanks for appreciation....Glad it helps

[@takemein]

You can also check here.
th-cam.com/video/zoJN-PVdeqc/w-d-xo.html

[@you-gn4eh]

Which book?

[@lalalalalala-cb8bn]

Which book?? Please do tell

[@kathy-leew3989]

My professor gave us a different approach as to how the dsDNA becomes ssDNA at the 13-mer region. They told us that the ssDNA-binding-domain in the DnaA Protein causes the strand separation and didn’t mention an introduction of topological stress due to the coiling of the DNA around the Protein DnaA.
I find your explanation much more logical. Thank you!

[@poosayfresh8880]

Best detailed video on entire TH-cam

[@nigelsimbarashe6433]

i like this, pure accurate dispensing of molecular biology knowledge. Thank you very much Sir

[@hussainbiology]

thanks for appreciation..Glad to know that it helps✌️

[@Rishab1702]

Wow sir u r an artist who explain it's knowledge in terms of art. Tysm for explaining this topic

[@hussainbiology]

Thanks Rishab for appreciation....Glad to know that it helps

[@bilaliyafcjrusson2967]

⭐⭐⭐⭐⭐ God bless you sir and shine like a star in the sky of knowledge......

[@SONALI_1]

Hussain biology is best as far I have watched videos ....he explains everything logically...whenever I have viva I visit his channel to clear my concepts just overnight ...its really helpful...I m again here for learning for my exam that is day after tomorrow 🙃.
THANK YOU SO MUCH SIR 💓

[@hussainbiology]

thanks Shweta for appreciation.... Glad u like my stuff

[@NaDee-mh2po]

I have a test for this on Thursday. Thank you for making it easier to understand.

[@hussainbiology]

Thanks Daniel for appreciation...

[@takemein]

You can also check here.
th-cam.com/video/zoJN-PVdeqc/w-d-xo.html

[@hamihamro]

Finest video on the topic in TH-cam ❤️

[@hussainbiology]

Appreciate that

[@rohanavinashphatak2747]

No words yar to express your marvelous teaching. I just love the way u proceed step by step. The most appreciative part is u directly come on the point rather than taking curves n turns and landing up confusing the audience unlike shomu does. Just excellent 👌👌👌👌. God bless. Live long

[@hussainbiology]

Thanks for appreciation...glad to know that it helps

[@ayushijaiswal1183]

This video is so old but still it is the best for this topic. Excellent👏

[@hussainbiology]

Glad you think so!

[@himanshusharma6016]

you are deserve more and more subscribers bro

[@nouriakhan8656]

MashAllah ...hats off to u .....brilliant lecture delivered ❤.....
Teach pharmacology as well...😢💔
will be thankful to u 😊...

[@hussainbiology]

Thanks for appreciation.. Glad it helps..
InshaAllah Pharmacology soom

[@nouriakhan8656]

JazakAllah ...

[@nifatjan7458]

Clear cut concepts....great explanation....thnx sir

[@hussainbiology]

thanks for appreciation....Glad to know that it helps

[@bhatjas1820]

yes.. they do... very much!!! great efforts👌

[@ayeshaali9392]

today its my paper & am here to get the summarized knowledge.
جزاك الله

[@hussainbiology]

Alhamdulillah...I am really glad to know that..... All the best

[@josephineravenclaw6262]

Finally ..... a perfect video😍. You desrve million subscribers 💯

[@hussainbiology]

thanks for appreciation..Glad it helps✌️

[@shivaniojha4344]

Thank you sir for making such nice videos
Your videos let us understand topics clearly in very less time..
Thank you so much

[@snehaldesai4423]

There are 5 copies of 9 mer sequence

[@AjGaming-vx2pc]

Thanks u so much
U make every concept very easy

[@hussainbiology]

Thanks buddy for appreciation...Glad to know that it helps

[@saikumargsaikumar8657]

I really like each and every video in Hussain biology ....concepts are really crystal clear.....keep it up

[@red8527]

Your graphics are spot on. 🔥

[@hussainbiology]

thanks buddy

[@sheikhnajmanajma4281]

Thank u sooo much ,this makes my day (respect from kashmir)👍

[@hussainbiology]

Thanks Najma for appreciation.....Glad to know that it helps...( from Kashmir too )

[@RohitPant04]

Great explanation, Hussain but doesn't Ori-c sire in prokaryotes contain 9 nucleotide motifs of 5 repeats & not 4 repeats as you mention here?

[@alisalisna2019]

I agree with you! There is for sure 5 repeats of 9-mer motif. Plus at the end of his lecture, he mentioned a DNA pol III holoenzyme, that in fact has three DNA polymerases (not just two!): one of them is working on the leading strand and another two on lagging strand - "trombone model".
Here is some evidence:
pubmed.ncbi.nlm.nih.gov/22157955/
www.ncbi.nlm.nih.gov/pmc/articles/PMC2859602/
th-cam.com/video/sxedBRA18Ro/w-d-xo.html

[@kaavyasurianarayanan8247]

I agree with you!!

[@risingsun9247]

You are right there are 5 R boxes instead of 4

[@risharajkhowa5060]

Yes , theta are 5 9mer repeats

[@RobertJurilj]

No, there are 4 of 9mer repeats in E.coli
He was right

[@nishanisharma6289]

👍Well explained Sir. Thank you so Muchhhhh

[@hussainbiology]

thanks for appreciation..Glad it helps ✌️

[@Mission-Omega.]

You are the boss of biochemistry,Sir.♥

[@hussainbiology]

thanks for appreciation

[@maxruphio5515]

Thank you very much Hussain Biology

[@hussainbiology]

Thanks Max for appreciation ....Keep sharing and supporting

[@ammaramehak9473]

Nice videos for post graduated students thanx

[@hussainbiology]

thanks Ammara for appreciation.... Glad to know that it helps

[@kaavyasurianarayanan8247]

Woaahh!! You are sooo good sir!! Thank you so soo much!! Really helped me!!

[@hussainbiology]

thanks Kaavya for appreciation.
Glad to know that it helps

[@barashakalita7772]

Does the four 9 mer sequence lies on the downstream of replication recognition sequence

[@vrindasingh1306]

Thank you so much sir, its really helpful to clear the concepts.

[@hussainbiology]

Thanks Vrinda for appreciation..Glad to know that it helps.

[@alfredafriyieasiedu]

Very detailed and understandable, thank you!

[@shivanithakur1372]

No doubt you videos are highly informative and great to clear concepts only problm what I found is clearity of voice.. Otherwise video is with great information

[@hussainbiology]

will improve

[@anamikagarg9703]

This is so helpful, Thanks much for making this.

[@hussainbiology]

thanks for appreciation

[@WasimAkram-tk9sh]

hats up sir
may allah blessed u sir

[@saibarsha1176]

Thanx sir for solving my doubt through this vdo

[@hussainbiology]

Thanks for appreciation

[@abuzarnaqvi2053]

Bestest explanation 👍👍

[@nithyapriya.n1047]

Very well explained sir...Thank you..

[@hussainbiology]

thanks for appreciation

[@purnimaash2063]

Your videos hlp me a lot, thnq bro.. keep it up

[@hussainbiology]

thanks Purnima for appreciation

[@misbahnaik4987]

Excellent explanation

[@hussainbiology]

thanks for appreciation..Glad to know that it helps ✌️

[@bidhisingh9982]

u r awesome my bro . thanks.....

[@girikowshik3724]

Very clear explanation sir

[@hussainbiology]

thanks for appreciation

[@omedulmondal8357]

Mashallah... Allah apko salamat rakhe...

[@hussainbiology]

Aapko b... ✌️

[@muskangoyal4030]

sir there are 5 9mer sequences rather than 4...

[@hussainbiology]

yes.. accepted.. there is a site missing

[@prakritisamnotra6671]

Thankyou so much for making this too easy

[@hussainbiology]

thanks for appreciation..Glad to know that it helps ✌️

[@ManpreetSingh-ds4nn]

What a nice explained sir

[@hussainbiology]

Thanks Manpreet for appreciation....Keep sharing and supporting

[@armaansidhu3018]

Why there are four 9 mer sequence on ori? Why R3 is not mentioned in the diagram ?

[@hussainbiology]

apologies... certainly there is one ori site missing

[@dr.muzafarhussain9821]

Nice explanation....make more vedios..

[@hussainbiology]

Thanks for appreciation

[@nukamadhuvani5749]

Super explanation thank you sir

[@whats_on_your_mind_asksbhavika]

You explained it so well. Thanks

[@hussainbiology]

thanks for appreciation

[@sidrakadhim5102]

Thank u so much, it is really helpful !!!

[@hussainbiology]

thanks for appreciation..Glad it helps

[@aashmagyawali6331]

Thank you so much for your effort.. clearly understood

[@hussainbiology]

thanks for appreciation..Glad it helps ✌️

[@vasudevkoundinya252]

thanks yr.. you worth respect in comment section..(at least)

[@hussainbiology]

thanks for appreciation....Glad it helps

[@laxmanhanji6301]

Simply supperb

[@WasimAkram-tk9sh]

sir we r waiting 4ur next lectures elongation n termination process ...Insha -Allah it will b very soon

[@hussainbiology]

InshaAllah Elongation and termination process coming up on following Monday

[@bhatsuriya172]

nice bro....!! as usual..👍👍👍

[@hussainbiology]

Thanks Suriya,,,,

[@Helpnote9987]

Does this process occurs from ori site of plasmid?

[@riyajiyani3844]

Are these videos enough to study for concept of CSIR NET JRF or GATE biotechnology

[@hussainbiology]

Yes definitively.....

[@romankhan2935]

Where did you learn this bro.

[@hussainbiology]

from books and internet

[@romankhan2935]

@@hussainbiology which book?

[@antoniab3356]

I am a Hussain Biology loyalist✊

[@hussainbiology]

Glad to know that... Lots of love

[@JulianTheHunter]

Perfect! Just what i needes :)

[@salmanfariz1052]

Thank you so much sir.great effort

[@hussainbiology]

Thanks Salman for appreciation

[@debaswapnaray3295]

But sir pehle dnaB bind karta he uske baad ssb protein nhi toh helicase kam nhi karega agar pehle ssb lagade toh...otherwise its a best explaination video

[@hussainbiology]

Thanks for ur feedback and that is right what u say .
I too have mentioned the same
@ 3:59
Thanks

[@BiotecBuzz]

Prepare lecture on DNA sequencing
Blue white screening
Rdt pcr types of pcr

[@schoolofscienced.r5816]

Very good 👍

[@tayyabsulehri439]

Good effort

[@AhmedShadi95]

Excellent!

[@hussainbiology]

thanks for appreciation..Glad to know that it helps ✌️

[@hafizmuhammadrehan074]

Ahaaa kea bat ha🤗🤗🤗🤗

[@mitynonang1372]

What does mers mean sir plz reply?????

[@hussainbiology]

Mer means part ( in Greek ).. like hexa-mer ( six part when we have Length of six oligonucleotides)

[@leapotocnik7170]

THANK YOU!!!

[@hussainbiology]

You're welcome!

[@ShayaqUlAbeerRasool]

Hussain You are making amazing content. Are you Kashmiri?

[@hussainbiology]

thanks brother... Yes i am Kashmiri

[@letstudy2425]

What is the function of DNA pol 1 ...if DNA poly 3directly coming after primase

[@shivaniojha4344]

Keep making more and more videos

[@bhatwasim6741]

Thanks Shabir saab

[@hussainbiology]

Shukriya Bhat Sahib for appreciation.

[@merve_n]

God bless you

[@Arrahaha]

The best you are.

[@hussainbiology]

thanks for appreciation

[@kashuvlogs08]

Sir your video is so good ...but agar ap ise thoda speed kam krke video bnaenge to or achee s smjh ayga ....thanku sir

[@hussainbiology]

thanks for appreciation... haan Zaroor , InshaAllah will be slowing down my speed.
Keep sharing and supporting ✌️

[@kashuvlogs08]

@@hussainbiology Okay sir .... During this quarantine weeks i want to clear genetic topics ...so plzz ap genetic ke topics upload kriye....thankuu

[@hussainbiology]

@@kashuvlogs08the best part is that i am making a series of videos for Translation which will help u InshaAllah..
Stay safe☺️

[@kashuvlogs08]

@@hussainbiology okay 😊

[@jorgeeduardocarrenozapata4243]

youre the man

[@tanu6464]

Thanku

[@verma_kartikey]

how does replication occur in bacteria during starved condition

[@TheZitface5]

5:05 I think you got your leading/lagging strand messed up

[@hussainbiology]

yes i have a mistake there....

[@ayeshafatima-lq1qp]

Thank you sir,make more videos on CSIR topics

[@hussainbiology]

Thanks Ayesha for appreciation....Glad to know that it helps.

[@firdoskhan5580]

I want the link on DNA replication on the Goole site ..... Can u plz provide it.......

[@akankshabhardwaj2877]

Can you plz tell the name of reference book.....plzzzzz

[@hussainbiology]

i use Lodish and Alberts cell biology

[@akankshabhardwaj2877]

@@hussainbiology thnku😊

[@hussainbiology]

@@akankshabhardwaj2877 My pleasure

[@jyotisoni9814]

Hey!
Hope u will reply soon.
I have my mol. Bio exam tomorrow and there is a topic written in my syllabus "structural genes (as +nt in mRNA) - existing gene number by kinetics of RNA driven reaction"
I m not able understand what should i write on this and also not getting it on google.

[@hussainbiology]

Hi Jyoti , have read ur query but a also couldn't find anything related to it.

[@jyotisoni9814]

@@hussainbiology Okay. Is that structure gene ....mean gene structure? In reference to internal organisation what it could be.

[@hussainbiology]

@@jyotisoni9814 Most probably it could be the Structural genes organisation ( structural genes include lac z lac y and lac A genes -operan ) there are several other structural genes but these are the most imp ones

[@jyotisoni9814]

@@hussainbiology okay....tnq so much.

[@dieungic4043]

Thank you.

[@hussainbiology]

You're welcome....

[@lonenaveed2870]

Thankyou so much sir

[@bidhisingh9982]

Ap jeeyo hazaro saaal.

[@hussainbiology]

Thanks Bidhi for ur support...keep sharing and supporting

[@soundariyasoundararajan9133]

sir in starting you said from 5'-3' but when Dna G Protein binds why you said from 3'-5' can you please explain sir

[@quranbydaniyal]

Antiparallel

[@bhatjas1820]

👏sir plz... do upload more videos

[@hussainbiology]

Thanks Bhat....for appreciation....Glad to know that it helps.

[@salehakhatoon3452]

wonderful masha allah

[@hussainbiology]

thanks for appreciation

[@anavictoriagonzalezcarreon252]

Excelent!

[@hussainbiology]

thanks Ana for appreciation..

[@swarnapravajenajena2803]

Tqq sir. i need dna replication NOTE

[@hussainbiology]

I haven't compiled notes yet.... Thanks for appreciation

[@ridhazainab3225]

are u from kashmir

[@hussainbiology]

Yes Ridha I am Kashmiri ....

[@biologytutelage6960]

The video is good... But i found it quite complex to understand.... It should be more simplified...

[@kavitaprajapati6208]

Sir iska pdf download kese kare

[@laxmanhanji6301]

Supperb

[@hussainbiology]

thanks for appreciation

[@joancynthia9393]

Good.. 🤗

[@hussainbiology]

Thanks Cynthia for appreciation.... Keep sharing and supporting......

[@monishas906]

Tq sir pls more and vedios

[@manishachougule3883]

Sir, which books do u refer for molecular biology?

[@hussainbiology]

Three Books :
✓ Lodish Molecular Biology
✓ Alberts Molecular Biology
✓ Cooper Molecular Biology