ALT, AST, ALP & GGT (Liver Function Tests) - How to Interpret

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  • เผยแพร่เมื่อ 12 มี.ค. 2021
  • In this TachyTutorial, we explore the basic principles of interpreting Liver Function Tests. We explain what the enzymes ALT, AST, ALP, GGT and what the clinical significance is if their levels are raised. We also explain some special relationships between these enzymes!
    Understand and review high yield topics in Medical Sciences and Clinical Medicine. Want to learn something quickly and do not want to waste too much of your precious brain space? Than this is the channel for you.
    Made for Students! Subscribe to Learn!
    DISCLAIMER: This video is made for educational purposes only and is not made for medical advice. Please consult a doctor or other qualified healthcare professional for medical advice. The information in this video only represents the knowledge of the individual speaking in it and not those of any institution or other individual(s). We are not responsible for any errors or liabilities held within these videos.
    #LiverFunctionTests #ALT #HowToInterpret

ความคิดเห็น • 298

  • @sadhucat4476
    @sadhucat4476 2 ปีที่แล้ว +35

    Like everyone else here is saying - this is an amazingly digestible breakdown of liver enzyme analysis. I actually feel like I have some rough idea of how to interpret values now. Thank you!

    • @TachyTutorials
      @TachyTutorials  2 ปีที่แล้ว

      Thank you for watching!

    • @HepatitisBChannelHepatitisB
      @HepatitisBChannelHepatitisB 10 หลายเดือนก่อน

      Seems way too dramatic bearing in mind everyone often has raised alt.... with every course of pain killers, pub visit, protein shakes use, junk food lifestyle and many passing infections. None of these raises represent liver damage... so maybe remove the damage and put back the function where it belongs

  • @MrSmith-yr9vk
    @MrSmith-yr9vk ปีที่แล้ว +76

    For me, my higher than normal liver function tests revealed a silent problem that was going on. My ALT and AST started getting out of range growing higher each year (Over a three year period by the lab work results). My ALT hit 153 and AST was 88. ALT by the chart was over 113 past normal and AST was 40 points over. So what was causing my Liver to start hitting the panic button??? Well, an ultrasound of the liver showed the Renal Cell Carcinoma that was growing on my right kidney. MRI showed the tumor growing on my left kidney. From what I have read, the ALT enzyme reacts when the RCC gets into the renal artery. Well, two surgeries later, loss of right kidney and a piece of my left my numbers are back in range. I was in good shape, non-drinker, non-smoker, exercised everyday. If your numbers are getting out of whack and your Dr's tell you to stop eating fast food (That's what the dude told me, turned out to be Cancer) just make sure to keep looking at the problem. My bad Liver Function tests saved my life because I kept trying to find out why it was bad and I indeed found out why.

    • @Neenah44
      @Neenah44 ปีที่แล้ว

      Did you have any other symptoms?

    • @MrSmith-yr9vk
      @MrSmith-yr9vk ปีที่แล้ว +9

      @@Neenah44 For RCC, not a single one. If I would have just done nothing, I probably would be Stage 3 or 4 by now. My Urologist said that if the tumors would have been reversed, the Ultrasound on my liver would not have seen the tumors and I would not have made 60. I was 46 when we found RCC Stage 2.

    • @Neenah44
      @Neenah44 ปีที่แล้ว +5

      @@MrSmith-yr9vk Thank you for answering me I appreciate it very much. I’m happy that you were persistent in finding out why your numbers were growing higher. You literally saved your life. A great lesson on advocating for ourselves! Thanks again. Happy new year! 😊

    • @MrSmith-yr9vk
      @MrSmith-yr9vk ปีที่แล้ว +3

      @@Neenah44 Happy New Year to you and you are very welcome. RCC was not the answer I wanted to hear, but it was the answer to my problem so far.

    • @ramathakur3667
      @ramathakur3667 ปีที่แล้ว +2

      @@MrSmith-yr9vk bro.... i have ....258.0 - AST,471.9 -ALT,221.9-GGTP,447.00 - ALP ............ i was used to be proper in shape with 83 kg BW...now it turned into 73 in just 2 weeks.... i used to hit gym.... no alcohol ..even not fast food intake.... nd now i fukd upp

  • @rosegallus4048
    @rosegallus4048 2 ปีที่แล้ว +36

    All I can say is WOW!
    I could not understand these enzymes any better.
    I like the fact that you started by highlighting where each one of them is found and that made it very easy to Interpret the results.
    Im officially your subscriber from now.

    • @TachyTutorials
      @TachyTutorials  2 ปีที่แล้ว +1

      Thank you so much for your great feedback! Very useful! Glad you enjoyed and welcome to the channel!

  • @aparnabiju1575
    @aparnabiju1575 3 ปีที่แล้ว +29

    The best video out there on LFTs!! Thank you so much!

  • @MomJ_
    @MomJ_ 3 หลายเดือนก่อน +2

    No one can do better explanation than this. i really find value

  • @youryoungmom3526
    @youryoungmom3526 9 หลายเดือนก่อน

    Beautifully done, sir!

  • @DrPrabhakarRao
    @DrPrabhakarRao 10 หลายเดือนก่อน

    Excellent presentation to Doctors and Patients

  • @RCRM22
    @RCRM22 2 ปีที่แล้ว +1

    Fantastic video. Thank you

  • @lizsave7204
    @lizsave7204 2 ปีที่แล้ว +10

    That truly was the best and most informative, easy to understand explanation ever. Thank you!

  • @vivekabhyankar6565
    @vivekabhyankar6565 3 ปีที่แล้ว +1

    Wonderful explanation. Keep sharing more

  • @obaahemaacandy9082
    @obaahemaacandy9082 9 หลายเดือนก่อน

    This is the best explanation ever…..

  • @lettymelton6613
    @lettymelton6613 ปีที่แล้ว +2

    Excellent presentation! Thank you very much!

    • @TachyTutorials
      @TachyTutorials  ปีที่แล้ว

      Appreciate the comments. Thank you very much

  • @EddyCor_Paris
    @EddyCor_Paris ปีที่แล้ว

    Very helpful video. Thanks a lot. 👍

  • @jahajoel
    @jahajoel ปีที่แล้ว +2

    This is awesome. I have actually learnt alot from watching this and am glad I found your channel. Please can you give us tutorials on lipids profile as well

  • @gafarolamilekanolanshile1714
    @gafarolamilekanolanshile1714 ปีที่แล้ว +2

    Thank you so much.... Best I have ever seen.

  • @huytiennguyen586
    @huytiennguyen586 2 ปีที่แล้ว +2

    Excellent explanation. Thank you.

  • @aintgonnaletuknow5758
    @aintgonnaletuknow5758 ปีที่แล้ว

    very clear explanation, thank you very much

  • @drhadizasuleiman717
    @drhadizasuleiman717 2 ปีที่แล้ว +3

    Your interpretation is amazing, i ws able to grasp it easily. Thank you so much, God bless you. Hadiza from Nigeria.

  • @mercyzengeni9391
    @mercyzengeni9391 3 ปีที่แล้ว +2

    Genius. amazing explanations

  • @justmontina
    @justmontina ปีที่แล้ว +1

    Thank you so much for the clear explanation!

  • @stanleycates1972
    @stanleycates1972 3 ปีที่แล้ว +11

    Excellent. Was diagnosed with autoimmune hepatitis and treated most of last year. Turned out to be an infected gall bladder.

    • @jjohnson9822
      @jjohnson9822 2 ปีที่แล้ว

      how u going now bro?

    • @stanleycates1972
      @stanleycates1972 2 ปีที่แล้ว +5

      @@jjohnson9822 good, except being 85. The body is worn out from overuse :)

    • @ragavansrinivasan1961
      @ragavansrinivasan1961 2 ปีที่แล้ว

      Good evening sir, were is treatment autoimmune hepatitis primary bailary colanjaitis.

    • @damariskendrick2591
      @damariskendrick2591 ปีที่แล้ว

      Hello Mr Stanley Cates. Did you have to take prednisone or azathioprine? Asking because I had the same diagnosis and my gallbladder removed.

  • @mehrabmanteghian8071
    @mehrabmanteghian8071 2 ปีที่แล้ว +1

    It was more than awesome! Keep up!

    • @TachyTutorials
      @TachyTutorials  2 ปีที่แล้ว

      Thank you! Glad you enjoyed 🙂

  • @mariashieladolosa8239
    @mariashieladolosa8239 ปีที่แล้ว +1

    Thank you so much for this very informative video.

  • @praveenmadhubhashana4185
    @praveenmadhubhashana4185 ปีที่แล้ว +1

    Thank you... you saved many hours of my study time 🥰❤️

  • @isaackaddu
    @isaackaddu 14 วันที่ผ่านมา

    Wow , Awesome thank you Doctor

  • @Gracey-yz8zn
    @Gracey-yz8zn ปีที่แล้ว +2

    thank you so much for this video and the important information included herein.. had lab tests done and both alt were aboeve normal, the 2nd result was even higher than the 1st and ast also was above normal but abdominal ultrasound shows normal liver impression..

  • @fatumafatuma4077
    @fatumafatuma4077 2 ปีที่แล้ว +1

    Wow thank u for this eloquency 👏🏻👏🏻👏🏻

  • @tahirhussain4488
    @tahirhussain4488 ปีที่แล้ว

    Very nice explained

  • @CCMforall
    @CCMforall หลายเดือนก่อน

    Excellent explanation❤

  • @fridaespinoza945
    @fridaespinoza945 ปีที่แล้ว +1

    Amazing explanation!

  • @dettevalderrama5387
    @dettevalderrama5387 2 หลายเดือนก่อน

    Very good explanation...❤

  • @andradesaav
    @andradesaav 3 ปีที่แล้ว +2

    Awesome video! New sub man

  • @sunilpanday1785
    @sunilpanday1785 3 ปีที่แล้ว +1

    Good explanation, thank you

  • @LearnNursingEasy
    @LearnNursingEasy 3 ปีที่แล้ว +2

    Good explanation, animations superb.

  • @ezvahedi1387
    @ezvahedi1387 ปีที่แล้ว +1

    great explanation, thank you very much

  • @darkmoon3646
    @darkmoon3646 2 ปีที่แล้ว +1

    U absolute gem Thankyou

    • @TachyTutorials
      @TachyTutorials  2 ปีที่แล้ว +1

      Thank you so much! 🙂🙂🙂

  • @augustfinn5704
    @augustfinn5704 2 ปีที่แล้ว +1

    Thank you thank you thank you! ❤️

  • @uatdks803
    @uatdks803 ปีที่แล้ว +1

    excellant teaching

  • @damariskendrick2591
    @damariskendrick2591 ปีที่แล้ว +1

    Thank you for this video.. God bless 🙏

  • @darshanimadhuwanthi9176
    @darshanimadhuwanthi9176 2 ปีที่แล้ว

    thank you. really really useful.

  • @naeemqureshi6485
    @naeemqureshi6485 ปีที่แล้ว +2

    Great lecture.

  • @ancabostinariu6550
    @ancabostinariu6550 ปีที่แล้ว

    Thanks great summary.

  • @rayreyes8497
    @rayreyes8497 ปีที่แล้ว +1

    Excellent explanation.

  • @DrNancyLivingCoCreatively
    @DrNancyLivingCoCreatively ปีที่แล้ว +2

    I suggest you look into anti dressants. I have MTHFR c677t. My liver detoxes 70% slower. I allowed myself to be put on an anti present well butrin an enzyme I a had under control rose.

  • @charlesnya5766
    @charlesnya5766 ปีที่แล้ว +2

    What could a high AST:ALT ratio (>2) with low to normal GGT suggest?

  • @fatm4403
    @fatm4403 ปีที่แล้ว +1

    Great vid
    Thanks!

  • @medicalbiochemistry_
    @medicalbiochemistry_ 3 ปีที่แล้ว +1

    Good job

  • @stronger3381
    @stronger3381 2 ปีที่แล้ว +1

    ty 4 the awesome video

  • @vacaspen5038
    @vacaspen5038 2 ปีที่แล้ว +1

    very helpful thanks

  • @bourethphay8136
    @bourethphay8136 ปีที่แล้ว

    This is the amazing video 🎉

  • @narminafandiyeva8875
    @narminafandiyeva8875 8 หลายเดือนก่อน

    Thank you, that was very easy to absorb 🙂

    • @TachyTutorials
      @TachyTutorials  8 หลายเดือนก่อน

      Thanks for watching 😀

  • @pradeepkumarsrivastava5890
    @pradeepkumarsrivastava5890 ปีที่แล้ว +6

    In India, we frequently find ALT values in thousands, 2 to 3 thousand , in case of Viral hepatitis

  • @labexamhints5963
    @labexamhints5963 2 ปีที่แล้ว +1

    Thanks. good and perfect

  • @asiaaslam4369
    @asiaaslam4369 ปีที่แล้ว +1

    Really superb

  • @KULDEEPSINGH-zr9vw
    @KULDEEPSINGH-zr9vw 2 ปีที่แล้ว +1

    Very informative

  • @toniaschianodicola2344
    @toniaschianodicola2344 2 ปีที่แล้ว +2

    Well explained

  • @zhenarwrya8808
    @zhenarwrya8808 ปีที่แล้ว

    Got ur subscription deserves it

  • @SGunawardane
    @SGunawardane 2 ปีที่แล้ว

    Brilliant

  • @yup8563
    @yup8563 2 ปีที่แล้ว +1

    Just amazing

    • @TachyTutorials
      @TachyTutorials  2 ปีที่แล้ว

      Thank you! Glad you enjoyed 🙂

  • @asiahwalid6178
    @asiahwalid6178 ปีที่แล้ว +1

    Thank you!

  • @b.b.finsclara3589
    @b.b.finsclara3589 ปีที่แล้ว

    Upon getting my Bloom simple tests results.....de hace discovered i am experiencing "LowLevels of GamaGlutamylTransferase" I am uncertain what that implies....i do know i am experiencing VeryLowEnergyLevels????

  • @annebeauclair5918
    @annebeauclair5918 2 ปีที่แล้ว +3

    what about NAFLÐ (non alcool fatty liver disease)?

  • @spinedoc18
    @spinedoc18 ปีที่แล้ว +2

    Could raised ALT and AST be due to beta blockers and/or anti-coagulants?

  • @johnbonamigo5696
    @johnbonamigo5696 ปีที่แล้ว

    So with a small raise in GGT on blood test but all others are fine is most likely cause I drank a shit ton of alcohol 4 days before during a crazy weekend?

  • @jonathanharina7556
    @jonathanharina7556 4 หลายเดือนก่อน

    Doc my ast is 21.3 and my alt is 26.5 which the ratio is .80 that is less than 2, but my upper right abdomen is painful and the right side of my ribs, what is that doc? Could you enlightened me for that situation

  • @catn9608
    @catn9608 2 ปีที่แล้ว +3

    Concise and to the point. So helpful! Thank you so much!

  • @vila4530
    @vila4530 2 ปีที่แล้ว +1

    Thank you so so much 😍😍

  • @ramankitbhai
    @ramankitbhai 2 ปีที่แล้ว +4

    Can anyone plzz explain me the difference between liver infection and liver damage???

  • @stanceworks7995
    @stanceworks7995 11 หลายเดือนก่อน

    my blood tests came back and everything was good except my ALP was very low - what does this mean? The lab did not explain anything. Can this be the reason for Rosacea and/or weight gain?
    My AST and ALT were normal

  • @gulumamu2472
    @gulumamu2472 2 ปีที่แล้ว

    i am hep b patient what test results interpret that i am in danger or out of danger?

  • @CatsAreNiceMeow
    @CatsAreNiceMeow 29 วันที่ผ่านมา

    I was diagnosed with fatty liver but my doctor said it is unnecessary for me to have a GGT test performed. Is this true?

  • @bobcocampo
    @bobcocampo ปีที่แล้ว +3

    What does it mean if there is no liver damage? Does it mean that it is functioning well?

  • @changing_life_with_Rk
    @changing_life_with_Rk ปีที่แล้ว

    My ast level is 36 and alt is 18 , but ast alt ratio is 2 , is there any problem?

  • @jean-francoisduquette8336
    @jean-francoisduquette8336 ปีที่แล้ว +3

    Hight GGT only is : Auto brewery syndrome is also known as gut fermentation syndrome and endogenous ethanol fermentation. It's sometimes called “drunkenness disease.” This rare condition makes you intoxicated - drunk - without drinking alcohol. This happens when your body turns sugary and starchy foods (carbohydrates) into alcohol.

    • @user-ne8vl2uh8g
      @user-ne8vl2uh8g 3 หลายเดือนก่อน

      What if you don't drink and no it's not

  • @coryturner9140
    @coryturner9140 2 ปีที่แล้ว +1

    What about alkaline phosphatase at first test 182 now 211, 5 weeks later and alt at 48? Thoughts? Everything else seems to be good

  • @riachinita8608
    @riachinita8608 10 หลายเดือนก่อน

    Thank yo so much

  • @DL-jf9fn
    @DL-jf9fn 2 ปีที่แล้ว +6

    Amazing video, thank you! if GGT, is raised and ALP is normal, accompanied by elevated AST and ALT (AST higher than ALT, but both raised), what is the likely outcome for that?

    • @andrewlobuznov
      @andrewlobuznov 2 ปีที่แล้ว +5

      Alcoholism 🔥

    • @brax5715
      @brax5715 2 ปีที่แล้ว +6

      @@andrewlobuznov what if you do not drink?

    • @brothertn708
      @brothertn708 ปีที่แล้ว

      How’s your liver doing now?

    • @mudassarjabeen7548
      @mudassarjabeen7548 ปีที่แล้ว +1

      Yes ,u also want to ask , same reports,,can't interpret

    • @mudassarjabeen7548
      @mudassarjabeen7548 ปีที่แล้ว

      @DL 0001

  • @NurseQuipy
    @NurseQuipy 8 หลายเดือนก่อน

    Normal AST &ALT but alightly high GGT ( results 43 &51) can chemo do this?

  • @JK-hf2cx
    @JK-hf2cx ปีที่แล้ว

    Very clear video. What is the potential diagnosis please if there is an isolated abnormal ALT of 127? I am talking about a young nondrinker who does not so suffer from haemochromatosis. I mention haemochromatosis because his serum ferritin is also high, as is his creatinine. No viral hepatitis detected.

    • @12mach
      @12mach ปีที่แล้ว +1

      Tell him cut pork out diet its high polysatured fats are higher than alcohol

  • @billwilson6199
    @billwilson6199 ปีที่แล้ว

    Alt 40. AST 30. Alp 47. Ggt 85u/l.
    Have not drank alcohol for 5 years. What’s up with ggt being 20 points out of range?

  • @wafulameshack5532
    @wafulameshack5532 2 ปีที่แล้ว +1

    Thumbs up👍👍👍

  • @SarathKumar-rz9pb
    @SarathKumar-rz9pb 2 ปีที่แล้ว +1

    Best video

  • @ragnaricks
    @ragnaricks ปีที่แล้ว

    I am 25 yrs old and my ALT came out 157.9 and AST at 78.7. WTF, can this still be lowered? It is 3x and 2x of the normal levels

  • @ChadTurnt
    @ChadTurnt ปีที่แล้ว

    What if my ast is slightly elevated am I okay ??

  • @praveennaidu9873
    @praveennaidu9873 ปีที่แล้ว

    My ast 52.8 and alt 86.1....sap 103 pl suggest it's ok

  • @densilcardna
    @densilcardna 2 ปีที่แล้ว +1

    You got a subscriber.

    • @TachyTutorials
      @TachyTutorials  2 ปีที่แล้ว

      Thank you and welcome to the channel! 🙂

    • @densilcardna
      @densilcardna 2 ปีที่แล้ว

      @@TachyTutorials Thank you.

  • @nainazia30
    @nainazia30 8 หลายเดือนก่อน

    ALt 180
    Ast 68
    What to treat for it??? Plz give me advice and tell me is it normal

  • @mard7569
    @mard7569 ปีที่แล้ว

    My test include AGPT and SGOT not sure what it means.

  • @chrisreynolds8939
    @chrisreynolds8939 2 ปีที่แล้ว +1

    Wishing you had included a low ALP result. Otherwise, great information.

  • @KingSlayer-qm6vi
    @KingSlayer-qm6vi ปีที่แล้ว

    Great analysis but i suggest you to use better microphone for sound quality

  • @Chrissy0325
    @Chrissy0325 ปีที่แล้ว +1

    My alt is 20 and my ast is 20. This is the second time they have been the same. Is the ratio important to look at? My ALP is within normal limits and my doctor didn't comment on it so I don't know if I should bring it up. I have been diagnosed with fatty liver in the past with NASH 1 but I lost about 50 lbs since then but gaining 15 back. My last CT Scan did not show fatty liver so I am just concerned about the ratio since my 15 lb gain.

    • @Jeswin_Jose
      @Jeswin_Jose ปีที่แล้ว +1

      Did you get the answer for your concern?..I also want to know whether the ratio is important or the values of AST and ALT are important.

  • @princesolanki8957
    @princesolanki8957 2 ปีที่แล้ว

    Ast Alt ratio is 1.35 normal or not.

  • @wixy369
    @wixy369 3 ปีที่แล้ว +2

    ihave an Isolated high GGT all others are normal, and im not an alcohol drinker, What could this isolated ggt mean?

    • @shoot4thstars
      @shoot4thstars ปีที่แล้ว

      I have the same, and it accompanies hepatobiliary problems. I have read, it can be indicative of inflammation of the bile ducts.

  • @iraklibokuchava8019
    @iraklibokuchava8019 2 หลายเดือนก่อน

    AlT - 37.0 U/I is normale range?

  • @user-ou8pe9it8j
    @user-ou8pe9it8j 2 หลายเดือนก่อน

    What about Liver Steatosis? NAFLD?

  • @rogerv2784
    @rogerv2784 2 ปีที่แล้ว +1

    Hello, my GGT numbers are coming out to 111 other than that everything else is good. I have over a year and a half with out drinking alcohol just recently i had 1 drink thats it. What are the factors that could be causing my numbers to continue to increase? And is it reversable? If so how can I drop the numbers?

    • @pavanpabbireddypavanpabbir1897
      @pavanpabbireddypavanpabbir1897 ปีที่แล้ว

      My ggt level went to 166 and i dont know what to do? Any suggestuons ?

    • @timh-c7186
      @timh-c7186 ปีที่แล้ว

      ​@@pavanpabbireddypavanpabbir1897 ...suggest low carb/keto diet

    • @timh-c7186
      @timh-c7186 ปีที่แล้ว

      sugar causes high GGT, as I understand it

  • @mouniral-bougha7481
    @mouniral-bougha7481 ปีที่แล้ว

    I had fever vomiting for a week then had my ultrasound and blood work done in the 11th day of my first symptoms
    My blood test showed multiple times higher liver enzymes alt was the highest tho.
    I started developing jaundice at the 10th day.
    I had my ct and another ultrasound by the end of the second week but it was all good except for a few lymphnodes enlarged next to the gallbladder.
    On the 19th day i had a new blood work and it showes all enzymes decreased drastically and it is not too far from highs normal levels. Thats being said bilirubin kept increasing and hit 125 umol/l while it was 77 in the first blood work.
    I am feeling much better but still cant eat normally because i get uncomfortable feelings in my guts
    Any ideas?

    • @user-zl3xs1cf8x
      @user-zl3xs1cf8x 11 หลายเดือนก่อน

      It sounds like a bile duct blockage perhaps? Blocked by sludge. The bible ducts release bile that aids in helping to break down the food we eat so the stomach can digest it. If there's a slow down in bile production, then it effects how we digest food and can cause stomach pain, but if it's mainly the Alt that's elevated, it can often point to liver and the Ast can be liver but very high can point to the billery system. I'm not a doctor, but since I have chronic liver disease, I would naturally do the research. Your P.C.P should get you set up with a G.I./ heptology Doctor. It's not like you will get any answers on these sites from an actual Dr. As they hate to give info without running their exams on the patient first, and perhaps to even get in trouble hand out info. But again you should see a specialist being a G.I. / heptology, I would!! Good luck.🙏

  • @ZahidHussain-ht4tw
    @ZahidHussain-ht4tw 2 ปีที่แล้ว +1

    Thanks sir 👍👍

  • @emmaw7853
    @emmaw7853 2 ปีที่แล้ว +1

    Thank you so much for sharing this info! I just received my blood test result and have high ALP. The rest are alright so now I can decide to do a bone scan first just to make sure everything is ok. Cheers!

    • @kittyarcade2296
      @kittyarcade2296 2 ปีที่แล้ว

      Mine started with ALP and then the rest started to elevate in a cyclical pattern. Just be sure to follow up every few weeks, months, whatever your doctor recommends.

  • @swhispers5023
    @swhispers5023 2 ปีที่แล้ว +1

    What if the ALP is LOW ?