ALT, AST, ALP & GGT (Liver Function Tests) - How to Interpret

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  • เผยแพร่เมื่อ 15 ม.ค. 2025

ความคิดเห็น • 339

  • @sadhucat4476
    @sadhucat4476 2 ปีที่แล้ว +41

    Like everyone else here is saying - this is an amazingly digestible breakdown of liver enzyme analysis. I actually feel like I have some rough idea of how to interpret values now. Thank you!

    • @TachyTutorials
      @TachyTutorials  2 ปีที่แล้ว +1

      Thank you for watching!

    • @HepatitisBChannelHepatitisB
      @HepatitisBChannelHepatitisB ปีที่แล้ว

      Seems way too dramatic bearing in mind everyone often has raised alt.... with every course of pain killers, pub visit, protein shakes use, junk food lifestyle and many passing infections. None of these raises represent liver damage... so maybe remove the damage and put back the function where it belongs

  • @MrSmith-yr9vk
    @MrSmith-yr9vk 2 ปีที่แล้ว +95

    For me, my higher than normal liver function tests revealed a silent problem that was going on. My ALT and AST started getting out of range growing higher each year (Over a three year period by the lab work results). My ALT hit 153 and AST was 88. ALT by the chart was over 113 past normal and AST was 40 points over. So what was causing my Liver to start hitting the panic button??? Well, an ultrasound of the liver showed the Renal Cell Carcinoma that was growing on my right kidney. MRI showed the tumor growing on my left kidney. From what I have read, the ALT enzyme reacts when the RCC gets into the renal artery. Well, two surgeries later, loss of right kidney and a piece of my left my numbers are back in range. I was in good shape, non-drinker, non-smoker, exercised everyday. If your numbers are getting out of whack and your Dr's tell you to stop eating fast food (That's what the dude told me, turned out to be Cancer) just make sure to keep looking at the problem. My bad Liver Function tests saved my life because I kept trying to find out why it was bad and I indeed found out why.

    • @Neenah44
      @Neenah44 2 ปีที่แล้ว

      Did you have any other symptoms?

    • @MrSmith-yr9vk
      @MrSmith-yr9vk 2 ปีที่แล้ว +9

      @@Neenah44 For RCC, not a single one. If I would have just done nothing, I probably would be Stage 3 or 4 by now. My Urologist said that if the tumors would have been reversed, the Ultrasound on my liver would not have seen the tumors and I would not have made 60. I was 46 when we found RCC Stage 2.

    • @Neenah44
      @Neenah44 2 ปีที่แล้ว +5

      @@MrSmith-yr9vk Thank you for answering me I appreciate it very much. I’m happy that you were persistent in finding out why your numbers were growing higher. You literally saved your life. A great lesson on advocating for ourselves! Thanks again. Happy new year! 😊

    • @MrSmith-yr9vk
      @MrSmith-yr9vk 2 ปีที่แล้ว +3

      @@Neenah44 Happy New Year to you and you are very welcome. RCC was not the answer I wanted to hear, but it was the answer to my problem so far.

    • @ramathakur3667
      @ramathakur3667 2 ปีที่แล้ว +2

      @@MrSmith-yr9vk bro.... i have ....258.0 - AST,471.9 -ALT,221.9-GGTP,447.00 - ALP ............ i was used to be proper in shape with 83 kg BW...now it turned into 73 in just 2 weeks.... i used to hit gym.... no alcohol ..even not fast food intake.... nd now i fukd upp

  • @rosegallus4048
    @rosegallus4048 3 ปีที่แล้ว +39

    All I can say is WOW!
    I could not understand these enzymes any better.
    I like the fact that you started by highlighting where each one of them is found and that made it very easy to Interpret the results.
    Im officially your subscriber from now.

    • @TachyTutorials
      @TachyTutorials  3 ปีที่แล้ว +1

      Thank you so much for your great feedback! Very useful! Glad you enjoyed and welcome to the channel!

  • @MomJ_
    @MomJ_ 10 หลายเดือนก่อน +4

    No one can do better explanation than this. i really find value

  • @aparnabiju1575
    @aparnabiju1575 3 ปีที่แล้ว +31

    The best video out there on LFTs!! Thank you so much!

  • @stanleycates1972
    @stanleycates1972 3 ปีที่แล้ว +14

    Excellent. Was diagnosed with autoimmune hepatitis and treated most of last year. Turned out to be an infected gall bladder.

    • @jjohnson9822
      @jjohnson9822 3 ปีที่แล้ว

      how u going now bro?

    • @stanleycates1972
      @stanleycates1972 3 ปีที่แล้ว +5

      @@jjohnson9822 good, except being 85. The body is worn out from overuse :)

    • @ragavansrinivasan1961
      @ragavansrinivasan1961 2 ปีที่แล้ว

      Good evening sir, were is treatment autoimmune hepatitis primary bailary colanjaitis.

    • @damariskendrick2591
      @damariskendrick2591 2 ปีที่แล้ว

      Hello Mr Stanley Cates. Did you have to take prednisone or azathioprine? Asking because I had the same diagnosis and my gallbladder removed.

    • @MsCarrionswarm
      @MsCarrionswarm 2 หลายเดือนก่อน

      Symptoms of infected gallbladder?

  • @obaahemaacandy9082
    @obaahemaacandy9082 ปีที่แล้ว +2

    This is the best explanation ever…..

  • @oldschoolguy80s
    @oldschoolguy80s 6 หลายเดือนก่อน +2

    Amazing doctor! Thank you for the interpretation! 🙏👍

  • @DrPrabhakarRao
    @DrPrabhakarRao ปีที่แล้ว +1

    Excellent presentation to Doctors and Patients

  • @gafarolamilekanolanshile1714
    @gafarolamilekanolanshile1714 2 ปีที่แล้ว +3

    Thank you so much.... Best I have ever seen.

  • @lizsave7204
    @lizsave7204 2 ปีที่แล้ว +11

    That truly was the best and most informative, easy to understand explanation ever. Thank you!

  • @lettymelton6613
    @lettymelton6613 2 ปีที่แล้ว +3

    Excellent presentation! Thank you very much!

    • @TachyTutorials
      @TachyTutorials  2 ปีที่แล้ว

      Appreciate the comments. Thank you very much

  • @rayreyes8497
    @rayreyes8497 ปีที่แล้ว +2

    Excellent explanation.

  • @drhadizasuleiman717
    @drhadizasuleiman717 3 ปีที่แล้ว +4

    Your interpretation is amazing, i ws able to grasp it easily. Thank you so much, God bless you. Hadiza from Nigeria.

  • @jahajoel
    @jahajoel ปีที่แล้ว +3

    This is awesome. I have actually learnt alot from watching this and am glad I found your channel. Please can you give us tutorials on lipids profile as well

  • @nickthrasher4948
    @nickthrasher4948 7 หลายเดือนก่อน +1

    Mine was due to alpha1antitrypsin deficiency! I think everyone with the high levels should be checked for this today! It’s not an expensive test and needs an early diagnosis when possible🙏

  • @praveenmadhubhashana4185
    @praveenmadhubhashana4185 2 ปีที่แล้ว +3

    Thank you... you saved many hours of my study time 🥰❤️

  • @ezvahedi1387
    @ezvahedi1387 ปีที่แล้ว +1

    great explanation, thank you very much

  • @mercyzengeni9391
    @mercyzengeni9391 3 ปีที่แล้ว +3

    Genius. amazing explanations

  • @delaagbeko-konu9893
    @delaagbeko-konu9893 6 หลายเดือนก่อน

    Well explained to my understanding. Thank you very much

  • @damariskendrick2591
    @damariskendrick2591 2 ปีที่แล้ว +2

    Thank you for this video.. God bless 🙏

  • @naeemqureshi6485
    @naeemqureshi6485 2 ปีที่แล้ว +2

    Great lecture.

  • @fridaespinoza945
    @fridaespinoza945 2 ปีที่แล้ว +2

    Amazing explanation!

  • @DrNancyLivingCoCreatively
    @DrNancyLivingCoCreatively 2 ปีที่แล้ว +4

    I suggest you look into anti dressants. I have MTHFR c677t. My liver detoxes 70% slower. I allowed myself to be put on an anti present well butrin an enzyme I a had under control rose.

    • @Orangina345
      @Orangina345 5 หลายเดือนก่อน

      What was high? I have ALP moderately high, GGT normal and. mTHFR mutation . Thanks!

    • @MsCarrionswarm
      @MsCarrionswarm 2 หลายเดือนก่อน

      Antidepressants cause problem in liver?

  • @LearnNursingEasy
    @LearnNursingEasy 3 ปีที่แล้ว +4

    Good explanation, animations superb.

  • @Gracey-yz8zn
    @Gracey-yz8zn 2 ปีที่แล้ว +3

    thank you so much for this video and the important information included herein.. had lab tests done and both alt were aboeve normal, the 2nd result was even higher than the 1st and ast also was above normal but abdominal ultrasound shows normal liver impression..

  • @aintgonnaletuknow5758
    @aintgonnaletuknow5758 ปีที่แล้ว

    very clear explanation, thank you very much

  • @huytiennguyen586
    @huytiennguyen586 3 ปีที่แล้ว +3

    Excellent explanation. Thank you.

  • @vivekabhyankar6565
    @vivekabhyankar6565 3 ปีที่แล้ว +2

    Wonderful explanation. Keep sharing more

  • @justmontina
    @justmontina 2 ปีที่แล้ว +2

    Thank you so much for the clear explanation!

  • @uatdks803
    @uatdks803 2 ปีที่แล้ว +1

    excellant teaching

  • @jean-francoisduquette8336
    @jean-francoisduquette8336 2 ปีที่แล้ว +4

    Hight GGT only is : Auto brewery syndrome is also known as gut fermentation syndrome and endogenous ethanol fermentation. It's sometimes called “drunkenness disease.” This rare condition makes you intoxicated - drunk - without drinking alcohol. This happens when your body turns sugary and starchy foods (carbohydrates) into alcohol.

    • @ValentinaKajcinovska
      @ValentinaKajcinovska 10 หลายเดือนก่อน

      What if you don't drink and no it's not

    • @edwardl.492
      @edwardl.492 2 หลายเดือนก่อน

      i have elevated GGT and i get high from sugary drinks.. that made a lot of sense

  • @CCMforall
    @CCMforall 8 หลายเดือนก่อน

    Excellent explanation❤

  • @mehrabmanteghian8071
    @mehrabmanteghian8071 2 ปีที่แล้ว +2

    It was more than awesome! Keep up!

    • @TachyTutorials
      @TachyTutorials  2 ปีที่แล้ว

      Thank you! Glad you enjoyed 🙂

  • @lb4660
    @lb4660 6 หลายเดือนก่อน +1

    Tacky tutorials Can the DTaP shot raise AST if given directly before blood work?

  • @dettevalderrama5387
    @dettevalderrama5387 9 หลายเดือนก่อน

    Very good explanation...❤

  • @bourethphay8136
    @bourethphay8136 ปีที่แล้ว

    This is the amazing video 🎉

  • @darkmoon3646
    @darkmoon3646 2 ปีที่แล้ว +1

    U absolute gem Thankyou

    • @TachyTutorials
      @TachyTutorials  2 ปีที่แล้ว +1

      Thank you so much! 🙂🙂🙂

  • @priscanaab9226
    @priscanaab9226 2 หลายเดือนก่อน

    Very educative

  • @andreatedtaotao2914
    @andreatedtaotao2914 3 ปีที่แล้ว +1

    Excellent presentation!!!! Thank you.

  • @isaackaddu
    @isaackaddu 7 หลายเดือนก่อน

    Wow , Awesome thank you Doctor

  • @pradeepkumarsrivastava5890
    @pradeepkumarsrivastava5890 2 ปีที่แล้ว +9

    In India, we frequently find ALT values in thousands, 2 to 3 thousand , in case of Viral hepatitis

    • @naman20gupta
      @naman20gupta 3 หลายเดือนก่อน

      Yes absolutely.. Patients need not worry as Hepatitis can cause ALT level as high as 10000 (as in my case). So be relaxed and get admitted under medical supervision immediately and you will be fine within weeks or maybe months..

    • @akkuverma2328
      @akkuverma2328 25 วันที่ผ่านมา

      Hi, do ast to alt ratio more than 2 always due to alcholic liver disease?is it possible to a person who never consumed alcohol?

  • @andradesaav
    @andradesaav 3 ปีที่แล้ว +2

    Awesome video! New sub man

  • @YaasiDominic
    @YaasiDominic 3 หลายเดือนก่อน

    Woow😮, very understandable

  • @ancabostinariu6550
    @ancabostinariu6550 2 ปีที่แล้ว

    Thanks great summary.

  • @AKm-cs7ju
    @AKm-cs7ju 3 หลายเดือนก่อน

    That was really beneficial 🤌🏼

  • @DoinMaBestt
    @DoinMaBestt 2 ปีที่แล้ว +1

    Great vid
    Thanks!

  • @RCRM22
    @RCRM22 3 ปีที่แล้ว +1

    Fantastic video. Thank you

  • @fatumafatuma4077
    @fatumafatuma4077 2 ปีที่แล้ว +1

    Wow thank u for this eloquency 👏🏻👏🏻👏🏻

  • @derickmartis220
    @derickmartis220 4 หลายเดือนก่อน

    good info thanks

  • @asiaaslam4369
    @asiaaslam4369 2 ปีที่แล้ว +1

    Really superb

  • @mariashieladolosa8239
    @mariashieladolosa8239 2 ปีที่แล้ว +1

    Thank you so much for this very informative video.

  • @tahirhussain4488
    @tahirhussain4488 2 ปีที่แล้ว

    Very nice explained

  • @toniaschianodicola2344
    @toniaschianodicola2344 2 ปีที่แล้ว +2

    Well explained

  • @narminafandiyeva8875
    @narminafandiyeva8875 ปีที่แล้ว

    Thank you, that was very easy to absorb 🙂

  • @asiahwalid6178
    @asiahwalid6178 2 ปีที่แล้ว +1

    Thank you!

  • @vila4530
    @vila4530 2 ปีที่แล้ว +1

    Thank you so so much 😍😍

  • @EddyCor_Paris
    @EddyCor_Paris 2 ปีที่แล้ว

    Very helpful video. Thanks a lot. 👍

  • @karenstanton5405
    @karenstanton5405 5 หลายเดือนก่อน

    Thank you l understand it better now

  • @eyob-x2n
    @eyob-x2n 12 วันที่ผ่านมา

    Thank U

  • @augustfinn5704
    @augustfinn5704 3 ปีที่แล้ว +1

    Thank you thank you thank you! ❤️

  • @stronger3381
    @stronger3381 2 ปีที่แล้ว +1

    ty 4 the awesome video

  • @vacaspen5038
    @vacaspen5038 2 ปีที่แล้ว +1

    very helpful thanks

  • @DL-jf9fn
    @DL-jf9fn 3 ปีที่แล้ว +6

    Amazing video, thank you! if GGT, is raised and ALP is normal, accompanied by elevated AST and ALT (AST higher than ALT, but both raised), what is the likely outcome for that?

    • @drendolob
      @drendolob 2 ปีที่แล้ว +5

      Alcoholism 🔥

    • @brax5715
      @brax5715 2 ปีที่แล้ว +6

      @@drendolob what if you do not drink?

    • @brothertn708
      @brothertn708 2 ปีที่แล้ว

      How’s your liver doing now?

    • @mudassarjabeen7548
      @mudassarjabeen7548 2 ปีที่แล้ว +1

      Yes ,u also want to ask , same reports,,can't interpret

    • @mudassarjabeen7548
      @mudassarjabeen7548 2 ปีที่แล้ว

      @DL 0001

  • @sunilpanday1785
    @sunilpanday1785 3 ปีที่แล้ว +1

    Good explanation, thank you

  • @yup8563
    @yup8563 2 ปีที่แล้ว +1

    Just amazing

    • @TachyTutorials
      @TachyTutorials  2 ปีที่แล้ว

      Thank you! Glad you enjoyed 🙂

  • @KULDEEPSINGH-zr9vw
    @KULDEEPSINGH-zr9vw 3 ปีที่แล้ว +1

    Very informative

  • @SarathKumar-rz9pb
    @SarathKumar-rz9pb 2 ปีที่แล้ว +1

    Best video

  • @zhenarwrya8808
    @zhenarwrya8808 ปีที่แล้ว

    Got ur subscription deserves it

  • @labexamhints5963
    @labexamhints5963 2 ปีที่แล้ว +1

    Thanks. good and perfect

  • @estelamino6356
    @estelamino6356 3 หลายเดือนก่อน

    Thanks

  • @wafulameshack5532
    @wafulameshack5532 3 ปีที่แล้ว +1

    Thumbs up👍👍👍

  • @annebeauclair5918
    @annebeauclair5918 2 ปีที่แล้ว +5

    what about NAFLÐ (non alcool fatty liver disease)?

    • @ThePartyyChat
      @ThePartyyChat 3 หลายเดือนก่อน

      Exactly this video is dumb trying to scare people

  • @darshanimadhuwanthi9176
    @darshanimadhuwanthi9176 3 ปีที่แล้ว

    thank you. really really useful.

  • @sudhapardhiphan5845
    @sudhapardhiphan5845 7 หลายเดือนก่อน +1

    wow. 👌

  • @medicalbiochemistry_
    @medicalbiochemistry_ 3 ปีที่แล้ว +1

    Good job

  • @riachinita8608
    @riachinita8608 ปีที่แล้ว

    Thank yo so much

  • @bobcocampo
    @bobcocampo 2 ปีที่แล้ว +3

    What does it mean if there is no liver damage? Does it mean that it is functioning well?

  • @densilcardna
    @densilcardna 2 ปีที่แล้ว +1

    You got a subscriber.

    • @TachyTutorials
      @TachyTutorials  2 ปีที่แล้ว

      Thank you and welcome to the channel! 🙂

    • @densilcardna
      @densilcardna 2 ปีที่แล้ว

      @@TachyTutorials Thank you.

  • @spinedoc18
    @spinedoc18 2 ปีที่แล้ว +2

    Could raised ALT and AST be due to beta blockers and/or anti-coagulants?

  • @phillipwalter8993
    @phillipwalter8993 5 หลายเดือนก่อน

    ALP elevated by osteoblasts,so bone disease perhaps but technically does not need bone destruction, so can differentiate early versus late Pagets on test questions

  • @ramankitbhai
    @ramankitbhai 2 ปีที่แล้ว +5

    Can anyone plzz explain me the difference between liver infection and liver damage???

  • @S.BOfficial786
    @S.BOfficial786 6 หลายเดือนก่อน

    The doctor told me my ggt level is slightly mildly raised im worried and dont understand this can you guide me more is this life threatening

  • @SGunawardane
    @SGunawardane 3 ปีที่แล้ว

    Brilliant

  • @JK-hf2cx
    @JK-hf2cx 2 ปีที่แล้ว

    Very clear video. What is the potential diagnosis please if there is an isolated abnormal ALT of 127? I am talking about a young nondrinker who does not so suffer from haemochromatosis. I mention haemochromatosis because his serum ferritin is also high, as is his creatinine. No viral hepatitis detected.

    • @12mach
      @12mach ปีที่แล้ว +1

      Tell him cut pork out diet its high polysatured fats are higher than alcohol

  • @ZahidHussain-ht4tw
    @ZahidHussain-ht4tw 2 ปีที่แล้ว +1

    Thanks sir 👍👍

  • @KingSlayer-qm6vi
    @KingSlayer-qm6vi 2 ปีที่แล้ว

    Great analysis but i suggest you to use better microphone for sound quality

  • @chrissoucy5322
    @chrissoucy5322 ปีที่แล้ว

    Can elevated diabetes numbers cause elevated elevated liver enzymes

  • @Gemsurbangarden
    @Gemsurbangarden 2 หลายเดือนก่อน

    What if you have high GGT (125) and slightly raised AST and ALT but normal ALP?
    Ultrasound showed fatty liver 18 months prior but since then the AST and ALT levels have reduced (although still elevated)

  • @CatsAreNiceMeow
    @CatsAreNiceMeow 8 หลายเดือนก่อน

    I was diagnosed with fatty liver but my doctor said it is unnecessary for me to have a GGT test performed. Is this true?

  • @charlesnya5766
    @charlesnya5766 2 ปีที่แล้ว +2

    What could a high AST:ALT ratio (>2) with low to normal GGT suggest?

  • @user-ou8pe9it8j
    @user-ou8pe9it8j 9 หลายเดือนก่อน

    What about Liver Steatosis? NAFLD?

  • @catn9608
    @catn9608 3 ปีที่แล้ว +3

    Concise and to the point. So helpful! Thank you so much!

  • @Chrissy0325
    @Chrissy0325 2 ปีที่แล้ว +1

    My alt is 20 and my ast is 20. This is the second time they have been the same. Is the ratio important to look at? My ALP is within normal limits and my doctor didn't comment on it so I don't know if I should bring it up. I have been diagnosed with fatty liver in the past with NASH 1 but I lost about 50 lbs since then but gaining 15 back. My last CT Scan did not show fatty liver so I am just concerned about the ratio since my 15 lb gain.

    • @Jeswin_Jose
      @Jeswin_Jose ปีที่แล้ว +1

      Did you get the answer for your concern?..I also want to know whether the ratio is important or the values of AST and ALT are important.

  • @obimpehbenjaminteye9100
    @obimpehbenjaminteye9100 6 หลายเดือนก่อน

    What if both alt and ggt raised.?

  • @stanceworks7995
    @stanceworks7995 ปีที่แล้ว

    my blood tests came back and everything was good except my ALP was very low - what does this mean? The lab did not explain anything. Can this be the reason for Rosacea and/or weight gain?
    My AST and ALT were normal

  • @Cand.yasmin
    @Cand.yasmin 7 หลายเดือนก่อน

    What if I only have elevated GGT but I don’t drink alcohol?

  • @johnbonamigo5696
    @johnbonamigo5696 2 ปีที่แล้ว

    So with a small raise in GGT on blood test but all others are fine is most likely cause I drank a shit ton of alcohol 4 days before during a crazy weekend?

  • @jonathanharina7556
    @jonathanharina7556 11 หลายเดือนก่อน

    Doc my ast is 21.3 and my alt is 26.5 which the ratio is .80 that is less than 2, but my upper right abdomen is painful and the right side of my ribs, what is that doc? Could you enlightened me for that situation

  • @swhispers5023
    @swhispers5023 2 ปีที่แล้ว +1

    What if the ALP is LOW ?