Pharmacology - DRUGS FOR ALZHEIMER'S DISEASE (MADE EASY)
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- เผยแพร่เมื่อ 22 พ.ค. 2024
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Alzheimer’s disease is a progressive neurodegenerative disorder that leads to symptoms of dementia. Current therapeutic options are limited to drugs that provide only mild symptomatic benefit. Alzheimer's drugs are believed to work by either preventing the breakdown of acetylcholine or blocking the toxic effects associated with excess glutamate in the brain. This pharmacology lecture covers topics such as pathophysiology of Alzheimer's disease, cholinergic hypothesis, amyloid hypothesis, Tau hypothesis, mechanism of action & side effects of cholinesterase inhibitors and NMDA receptor antagonist, future of Alzheimer's treatment. Drugs mentioned include; Donepezil, Rivastigmine, Galantamine, and Memantine.
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0:00 Pathophysiology of Alzheimer's disease
1:56 Cholinesterase inhibitors
4:00 NMDA receptor antagonist
5:24 Future of Alzheimer's treatment
Thank you so much for these videos! I'm studying for a Pharmacology NBME and these are super helpful!
Love your videos..you ve explained very well almost all topics that I watched on your channel.. keep doing this great work! ❤
Ur appreciation is not possible by words...beyond word👏👏
Absolutely excellent video particularly on the action of the two drugs. Very well explained.
Ur videos have totally cleared my concept of pharmacology and understanding! I love ur voice and ur way of explaining....i love the animation and graphics u use...! Keep going bro! Always on a lookout for ur new videos...please make more videos!
Your videos are really helpful!
It’s one source from which I take help when I get stuck making lectures for my channel!
Keep it up and upload more often! 💯
I am watching ur channel too u r great👍👍👍
Thank you very much for this video! It provided me with the basic knowledge I need for the pharmacology of Alzheimer's disease.
Thank u so much speed pharmacology bro 😊😊....god bless u
Thank you so much for teaching in so easy way💕
Your videos helped me to understand the basics of pharmacology, they are short, but informative and as a visual learner I could easily remember them. Just wanted to say thank you, I really appreciate the effort in the videos, you really made me interested in pharmacology and I'm so eager to learn more from you. The world needs more teachers and lecturers like you, keep up with the good work!
Hey where are you from?
Thanx for your lectures...God bless you
Blessed to have you ❤💯
Your videos are amazing I wrote everything you said ...you only have to upload more video to reach 1 million ...good luck
Thank u sir for the videos....
It makes pharmac super dooper easy💯
Hi sir , your way of simple explanation is superb , like u r covering almost every topic pharmacology within minutes it is very hepful to all medical students ❤
thank you so much for making this! I am in NP school and textbooks don't make sense to me. I have passed my exams thanks to your other videos. I hope to pass this upcoming one well too! Thank you!
Congrats for 200k subscribers.only thing your videos came very late or larger duration. Please upload minimum one video per month.
Very helpful and informative video….Thanks
Come up with more videos,i love your channel
Please upload fast you are helping a lot thanks sir❤❤
Amazingly explained!!
If you enjoyed this video, you may also want to know that there's been recent research that uses a functional medicine approach to find possible root causes of Alzheimer's Disease!
Lovely video thank u so much!
If you enjoyed this video, you may also want to know that there's been recent research that uses a functional medicine approach to find possible root causes of Alzheimer's Disease!
Thank you so much sir!
This is such a great video. I only knew about the Tau and Beta Amyloid hypotheses.
There now is a monoclonal antibody that works to target Beta-amyloid plaques and help clear them. Although it does a great job clearing the plaques, it only slows progression of Alzheimers, and does nothing to reverse the problems associated with cognitive decline. Lecanemab has had successful trials AND been approved by the FDA for treatment to slow the progression of EARLY Alzheimers. It has not been tested on later stage alzheimer's patients.
Nice sound effect sir.
Thank you so much ❤️
U r the best in pharma🤞🤞👍👍
thank you!
Thank you!!!
thank you very much!!!
Thank you
woooaw this was awesome .
Excellent
may ALLAH help u ......one of the best video
Very good video, love all of your videos,
but the sound effects really kill the line of thought and focus
Thanks
I did some research and found out that NEPRILYSIN INHIBITORS are helpful. It is more efficient in destroying Beta Amyloid proteins and preventing plaque formation. However this is still not fully approved for clinical treatments. Would like to know your thoughts...
Hi
I'd just like to ask if the mechanism of action of neprilysin inhibitors in this regard is known. And if there are side effects
Amazing work! Please upload more topics!
If you liked this video, you may also want to know about research that looks at possible root causes for Alzheimer's! Check out the work of Dr. Dale Bredesen. He had a 2018 study in the Journal of Alzheimers Disease & Parkinsonism. The study is titled: "Reversal of Cognitive Decline: 100 patients." It's fascinating stuff!
Please do a video on anti-rheumatic drugs
Sir plz do videos on endocrine system
Could you make video about angina pectoris
Hi..can you please make about antineoplastic??..pls..
Very good video! I have one question though- Do doctors prescribe both Cholinesterase inhibitors and NMDA antagonists or just one of the medications?
Combinations of both are commonly prescribed
May I have your permission to share this video in a continuing education course? Thank you for your consideration!
Good work
If you liked this video, you may also be interested to know about possible root causes behind Alzheimer's! For this, look at the work of Dr. Dale Bredesen at Duke University! He looks at possible causes like: pathogens/gut infections, intestinal permeability of the gut (leaky gut), microbiome imbalances, insulin resistance, nutrient deficiencies, hormone imbalances, and toxin exposures!
@@OswaldDigestiveClinic thank you very much🙏
The best
thank you.
If you're interested in this video, you may also be interested to know that gut health can certainly play a role in Alzheimer's! Functional medicine is an amazing tool to reverse Alzheimer's. It involves looking at the root cause(s) behind illness, and healing the gut is a part of that!
You deserve my 9k not my uni god bless you 😭❤️
Nice.
You are real superhero
Lv ❤from india
You forgot the hypothesis of Insulin Resistance of the Brain preventing glucose uptake by the neurons. Given that ketone supplementation improves cognitive function in Alzheimer's patients it seems this one is the correct hypothesis.
the sad horn got me lol
Hello! Can someone tell, how does a regular daily consumer identify and distinguish a pharmaceutical grade drug in the market? Any signs, symbols or labels we can look for?
There are so many bad quality, impure over the counter drugs sold. So we have to know.
honestly these are all prescription drugs, your MD/physician should be prescribing them to you and then your pharmacist will prepare and deliver them, there should be no market involved. any licensed pharmacist could help with this.
Can I take this to learn better?
Kindly let me know how Citicolin works ?
Is this only for people with Alzheimer’s? It seems like this has benefits to increase and improve healthy young people’s mental capabilities as well? Out of all the side effects mentioned that were worrying to me the worst was insomnia and the effect of these drugs are temporary! Could students use these drugs to study? As in low dosage and responsible use?
Hi, I'm Poeuso from Cambodia.could I ask you a question which not involve the content ? between alfacalcidol and calcitriol for patient had total remove thyroid and parathyroid which one is better ?
Calcitriol
how do i gime my tuiton to you and not my college?
TY for the videos. One note: Memantine causes CONSTIPATION.
excellent video. .. accent similar to ElectroBOOM?
I hope I can ace my test huhu
Good news! A new study found good sleep can prevent Alzheimer's in the future.
thats fantastic, anything we can do to ease the burden on our bodies will ultimately be reflected in out body. The best thing we can do for our body is to be active. 15 minutes of walking a day can actually be life saving for your heart and your brain.
lol, love the sound effects
Why memantine causes constipation ?
can you make vitamins drugs. huhuhu from Philippines. 🧡
انت عظييم يابه
*Hi ‘Speed Pharmacology’ Merci infiniment. Outstanding video. Question, your accent? I have five accents. Finnish, Swedish, English, German French and Thai. Accent in every language. How about you? Greetings from THAILAND* th-cam.com/video/VOggAvPuLmM/w-d-xo.html
please link your references 💕💕💕
Mainly used Pharmacology lippincott's illustrated reviews series 5th edition (ISBN-10: 1451113145), and Basic & Clinical Pharmacology, 13th edition (ISBN-10: 0071825053).
Memantine doesn't cause diarrhea and insomnia, it causes constipation and somnolence
huh what about piracetam?
i have adhd.. and im a physiotherapy student.. i failed pharma and im trying my best rn to study but wallahy its not working..
All thanks to Dr Aba for curing me from Alzheimer’s disease am forever grateful
Whose Dr Aba and how were you cured
Please we need a video about migraine
If you want whole knowledge about rivastigmine tablet please visit once -medicosearch1.blogspot.com/2023/09/Rivastigmine%20Drug-Anti%20Alzheimers%20Drug-Top%20brand%20names%20of%20Rivastigmine.html
Can somebody please tell me how the hell to remember all these names 😢 for life time...
If you want whole knowledge about rivastigmine tablet please visit once -medicosearch1.blogspot.com/2023/09/Rivastigmine%20Drug-Anti%20Alzheimers%20Drug-Top%20brand%20names%20of%20Rivastigmine.html
There is a only blog where you learn all in easy way
#Awards schönen ist Gute zu Videos
Plant based diets show best prevention and outcomes for this disease
How could Antibodies be used in the brain? I doubt they can pass BBB haha
www.nature.com/articles/news.2011.319
The Chandigarh Ayurved Centre provides various herbs that generally act on memory & treat all the symptoms related to Alzheimer’s patients. A kit named “Alzheimer’s Go Kit” is introduced specially for Alzheimer’s patients. This kit comprises five products Brahmi vati, Brodley syrup, Nerve Up Tablet, Tagaradi churna, & Brain Relaxant churna.
Extra sound effects were extremely annoying
Sorry
Thanks for the feedback. This was the first video I used them in so I probably went overboard but the good news is that since then I tried to use them much less in subsequent videos
2w saw♥️♥️
Your explain method is good we can understand easily but u should improve by
1. Defination
2. types of drug
3. Mechanism of action
4. Advers effect
5. Threaputic use
6. Side
awre
i fart huge amount of gas
This is one of your best videos! Very informative, well explained, and fun to watch! Thanks 👍
If you liked this video, you may also want to know that it's estimated that 45 million out of the 328 million people in the U.S. will have Alzheimers! That's 13.7%!!
Thank you