I love how he says ''I hope you enjoyed this video'' as if he didn't just save my ass explaining everything a lot more clearer than any teacher ever could ! Like I more than enjoyed this video !
@Speed Pharmacology, Hello, I apologize for commenting 4 years too late but I just read a recent study where the tolerance of benzodiazepines regarding anxiolytics is inconclusive compared to tolerance of sedation and anti-convulsive properties. In other words, long term usage of benzodiazepines had insomniacs increase their dosage to get the same effect, same with seizures, however regarding anxiety, it still was effective at that dose even after long term usage. Have you heard of anything like this?
You do such an amazing job at simplifying difficult things with your adorable illustrations and organized points. Thank you for making me enjoy Pharm.❤️
ahhh personal subject. I got hooked on benzos in 93, I had a friend who was in a naval pharmacy. He stole and sold several types oxapam, Xanax restoril halcion and valium 100$ for 100 pills I took about 900 pills in a few months. In the end I just down the pills like candy. These made me insane. Halcion was really weird, I loved them they gave me energy and enthusiasm Later on 2018, I figured out where to get old barbiturates, I'll just say occasionally an old pharmacy building gets cleared, in storage is many bottles of drugs, I had unopened bottle of secanol amobarbital pheno, barbital butisol cyclo and delvinal, Miltown and amo,dextro speed Speed great Miltown was garbage.maybe it was bad I Never been that wasted, once on seco and pheno I went in to black out, I can not remember 16 days Falling memory blossom and unable to figure out anything, like light switch or remote, dump drinks because you don't know where your mouth is 1 ate 90 1.5 grain pheno but lived. I have been strung out on both Barbs Will kill you
Barbiturates snowed me out. Benzodiazepines help my Anxiety disorders greatly. Hypnotic Z-Drugs help when monitored carefully. Was on Zaleplon. Now on Zolpidem 12.5. Sleep great and wake up refreshed. Good video! ✌
I wanted him to explain how to make these, so many people want to take these meds off the market. if they improve the quality of life for people under a doctor's care, I'm all for them.
I’m a researching parent and have a child with epilepsy. The company Sabril required me to sign a waiver for their drug Vigabatrin. I read that it was a permanent GABA inhibitor and found little else on the subject matter. Could you please do a presentation for how the drug Vigabatrin works on the brain 🧠? Also could you please explain what permanent GABA inhibitors do in other areas such as emotional effects and physical? Thank you 🙏 this information would be very appreciated.
Non-benzos definitely work as anxiolytics. Also zolpidem causes profound hallucinations/delerium at higher doses. Have you covered chloral hydrate and lesser known GABAergic CNS depressants?
This was perfect! My patient asked why Ambien causes crazy sleepwalking episodes but not so much Ativan... This is perfect for comparing the different gaba binding! Thank you so much
I am 16 and take Zolpidem tartrate once in a month when I am unable to sleep. It makes you go crazy if you do not fall asleep as soon as you take it. The biggest thing is that you do not remember what happened during such a crazy episode. I try hard to remember but it seems as if 90 percent of what happened is forgotten. Therefore, I request everybody to take Zolpidem with caution by taking it JUST 1 MINUTE BEFORE GOING TO SLEEP
Cheers for the Video clip! Apologies for the intrusion, I am interested in your initial thoughts. Have you tried - Nanackson Guardo Philosophy (Have a quick look on google cant remember the place now)? It is an awesome one off product for revealing the secret to get rid of panic attacks without the hard work. Ive heard some great things about it and my cousin got great success with it.
Get Oxycodone, Adderall, Percocet, Xanax, Valium and other drugs for your ADHD, ADD, Anxiety, Depression, Chronic Pain. Insomnia. No prescription required,. visit: darkfax.com
I am an avid #MentalHealthAwareness advocate and performer, and I love this so much. I travel the country trying to bring that awareness on stages, in classrooms, hospitals, and on my TH-cam channel, so I get excited when I see other advocates. 💙❤
What phrases can I use to research why Barbiturates have an extreme stimulatory effect on me (think aggressive drunken sailor on speed for many hours). I’m trying to understand how to gain support from a medical system where a majority of drugs cause an opposite intended primary &/or secondary effect. Beyond the redhead gene, and simple allometrics, there must be more useful keywords for me to use in my (as yet) epic blind research. - grateful for any useful insights & references.
we also use: - Antihistamines for Situational Insomnia (Hydroxyzine) - Chloral Hydrate for Short Term Treatment of Insomnia (for extremes of age: Elderly and Children) - some Antidepressants/Antipsychotics/Beta Receptor Blockers can be used as Anxiolytics
A very little known fact is that benzos are actually even more dangerous to quit than opiates like heroine and fentynal. It’s literally the most dangerous class of drugs to quit. I’m not exactly sure why but it kills lots of people who go cold turkey
i love your videos..They are informative yet entertaining..I wish you would make videos covering drugs used to treat endocrine disorders such as hypo/hyperthyroidism, acromegaly, cushing and addison's disease
My personal (non-medical professional) opinion is that; society shouldn't have banned GHB as a sleep aid. Prescribing hypnotics doesn't seem to provide deep REM 2 sleep in the same way that GHB did for those with sleep issues. I would love to hear your thoughts on this. :)
Most z-drugs do, in fact have considerable anxiolytic properties. I think that’s also why they are so disinhibiting. You can’t bind to the literal benzodiazepine site as an agonist without producing diminished panic and anxiety.
I used benzodiazepines as sedatives for years what will happen is they will become a bigger problem than the reason why you started using them in the first place. If you are using benzodiazepines occasionally and not as a nightly or daily medication . Be careful know the drug you take by taking with your pharmacist who is a chemist 🧪 and knows the effects of medication. Do not tell him why you are taking it this might cause him her to be One sided with what they are telling you. If you ask about a drug that will be the information they give you based on your question and not usage of your medication . Benzodiazepines are 60 times worse than heroin to withdraw from your first month every gram of fat on your body will be eaten to get the drugs out of it then you start withdrawals and it sucks and you may not be capable of working or functioning normally in society . This does not last forever. You need to eat right and not abuse yourself. I know drug addicts and addiction. When a drug addict stops using drugs what happens is your body is trying to heal and you will find that you have more health issues than you believed you had. When you are poisoning your body on a daily basis your body is fighting for your life and is focused on the abuse it is receiving. Once your body realizes that it is not being poisoned daily it will now focus on other problems. As a person who spit my teeth out and tore muscles right off the bone 🦴 because they said they can not help me but I convince them otherwise after the physical damage that was occurring. With benzodiazepines do your research know what you were doing do not rely on anybody else to tell you as well speak with people who have honestly been through it and not pimping a narrative .
I'm stiff confused as to how barbiturates attach to the GABAa/b receptor sites, and yet are not supposed to bind to the GABAa/b sites. Aren't they the same place?
🚀 Elevate Your Pharm Game! 📚 Join Patreon for A+ Study Notes!
👉 www.patreon.com/speedpharmacology 👈
@InPharmD_ Discover the fascinating origin of the Essential Medicines List (EML) in this engaging animated explainer video! 🌍💊
I love how he says ''I hope you enjoyed this video'' as if he didn't just save my ass explaining everything a lot more clearer than any teacher ever could !
Like I more than enjoyed this video !
@Speed Pharmacology, Hello, I apologize for commenting 4 years too late but I just read a recent study where the tolerance of benzodiazepines regarding anxiolytics is inconclusive compared to tolerance of sedation and anti-convulsive properties. In other words, long term usage of benzodiazepines had insomniacs increase their dosage to get the same effect, same with seizures, however regarding anxiety, it still was effective at that dose even after long term usage. Have you heard of anything like this?
This proves that complicated subjects can be so simple to understand when explained effectively. The school makes it so hard.
100%
This channel has literally helped me through pharmacy school!
th-cam.com/video/dD5eWuOddXE/w-d-xo.html
Structure activity relationship of barbiturates
That is actually really cool! I also want to attend pharmacy school in the future:))
same yr same
And me through medical school!
Yeah it's really helpful
You do such an amazing job at simplifying difficult things with your adorable illustrations and organized points. Thank you for making me enjoy Pharm.❤️
It is an impressive skill to make the complex look simple. Your combination of clear explanations and good images is outstanding. So well done!
ahhh personal subject.
I got hooked on benzos in 93, I had a friend who was in a naval pharmacy.
He stole and sold several types oxapam, Xanax restoril halcion and valium
100$ for 100 pills
I took about 900 pills in a few months. In the end I just down the pills like candy.
These made me insane. Halcion was really weird, I loved them they gave me energy and enthusiasm
Later on 2018, I figured out where to get old barbiturates, I'll just say occasionally an old pharmacy building gets cleared, in storage is many bottles of drugs,
I had unopened bottle of secanol amobarbital pheno, barbital butisol cyclo and delvinal,
Miltown and amo,dextro speed
Speed great
Miltown was garbage.maybe it was bad
I Never been that wasted, once on seco and pheno
I went in to black out, I can not remember 16 days
Falling memory blossom and unable to figure out anything, like light switch or remote, dump drinks because you don't know where your mouth is
1 ate 90 1.5 grain pheno but lived.
I have been strung out on both
Barbs Will kill you
For God's sake never attempt to try them again and thanks fr sharing and you should continue to aware ur fellows around u
Sam hope your ok your talking 1983 it’s almost 2020 30 yrs ur brain has to be fried be careful get clean
What do you mean by 1.5 grain?
@@kevinpatrick4408 I think a grain is a fraction of a gram its about 50 milligrams so 1.5 grain would be 75 milligrams
@@phazzle3644 Thank you
0:27- GABA
2:18- Limbic System
3:08- Pharm Overview
3:34- Benzodiazepines
5:18- Barbiturates
6:55- Non- Benzodiazepine Hypnotics
Barbiturates snowed me out. Benzodiazepines help my Anxiety disorders greatly. Hypnotic Z-Drugs help when monitored carefully. Was on Zaleplon. Now on Zolpidem 12.5. Sleep great and wake up refreshed. Good video! ✌
God bless you! I've always struggled with pharmacology and this has made things infinitely easier!!
Thank you soo much for making pharma easy for us.. helping in 3rd year MBBS❤
Goooood onyaaa im addicted to benzos with no education no job
Thank God i found this channel just in the beginning of the course sem .... I will be following up for more thank you ✨
These are seriously so good. Not gimmicky, straight facts. Thank you.
thanks. please continue. you’re my favorite pharm tutor.
Crisp and beautifully summarised without missing the essential details.
What a explanation you are the best pharmacology teacher
Omds you’re amazing 😭😭🥺 Clear explanations and easy to follow diagrams!
This guy is doing amazing jobs !!
Thank you
Thank you for this ,am preparing for my exams and the all thing has helped me
This video is simply awesome. Thank you!
before i go through books i watch your videos. . . . thank a lot " speed pharmacology "
THANK YOU SO MUCH! IVE FINALLY UNDERSTOOD OUR LESSON!
thank you so much... as always made my preparation so easier.. god bless us with more of your videos..
I absolutely love all your videos!! Thank you so much for making pharmacology so easy and understandable!!!!!
I wanted him to explain how to make these, so many people want to take these meds off the market. if they improve the quality of life for people under a doctor's care, I'm all for them.
Easy to understand and so clear! Thank you w. Respect!
Thank you so much. This video pretty much summed up my entire lecture.
Please increase the frequency of videos.. you are amazing!
Am now a consultant psychiatrist, because of this channel
Finally i found a really useful channel. Thanks a lot
This channel is helping me so much for nursing school. Straight to the point with great graphics!
Thak you very much for videos! Animations explain very well even if too speedly! I say 16 minutes for 16 days!
I’m a researching parent and have a child with epilepsy. The company Sabril required me to sign a waiver for their drug Vigabatrin. I read that it was a permanent GABA inhibitor and found little else on the subject matter. Could you please do a presentation for how the drug Vigabatrin works on the brain 🧠? Also could you please explain what permanent GABA inhibitors do in other areas such as emotional effects and physical? Thank you 🙏 this information would be very appreciated.
CBD OIL WITH "TERPINES" !!!
ketogenic diet
Holy shit they made you sign a waiver
Theese videos are life saving
Non-benzos definitely work as anxiolytics. Also zolpidem causes profound hallucinations/delerium at higher doses.
Have you covered chloral hydrate and lesser known GABAergic CNS depressants?
This was perfect! My patient asked why Ambien causes crazy sleepwalking episodes but not so much Ativan... This is perfect for comparing the different gaba binding! Thank you so much
I love Lorazapam yum yum yum yum im addicted
@@iridiumFalcon You won't be in another 6 months
I am 16 and take Zolpidem tartrate once in a month when I am unable to sleep. It makes you go crazy if you do not fall asleep as soon as you take it. The biggest thing is that you do not remember what happened during such a crazy episode. I try hard to remember but it seems as if 90 percent of what happened is forgotten. Therefore, I request everybody to take Zolpidem with caution by taking it JUST 1 MINUTE BEFORE GOING TO SLEEP
not all heroes were cape and you are the proof hahha
HE ISNT A CAPE YOU RACIST
@@dumper926 who made you captain of the cape club? If the man wants a cape I say let him have his cape and eat it too.
Karl Marksman “captain of the cape club” I’m dead 🤣
Cheers for the Video clip! Apologies for the intrusion, I am interested in your initial thoughts. Have you tried - Nanackson Guardo Philosophy (Have a quick look on google cant remember the place now)? It is an awesome one off product for revealing the secret to get rid of panic attacks without the hard work. Ive heard some great things about it and my cousin got great success with it.
Get Oxycodone, Adderall, Percocet, Xanax, Valium and other drugs for your ADHD, ADD, Anxiety, Depression, Chronic Pain. Insomnia. No prescription required,. visit: darkfax.com
I am an avid #MentalHealthAwareness advocate and performer, and I love this so much. I travel the country trying to bring that awareness on stages, in classrooms, hospitals, and on my TH-cam channel, so I get excited when I see other advocates. 💙❤
NICE ADVERTISEMENT YOUR ACTING IS SO GOOD I ALMOST DIDNT NOTICE IT WAS AN ADVERTISEMENT
I would like to know how ethanol (alcoholic beverages) works compared to benzos and barbiturates etc.
What phrases can I use to research why Barbiturates have an extreme stimulatory effect on me (think aggressive drunken sailor on speed for many hours). I’m trying to understand how to gain support from a medical system where a majority of drugs cause an opposite intended primary &/or secondary effect. Beyond the redhead gene, and simple allometrics, there must be more useful keywords for me to use in my (as yet) epic blind research. - grateful for any useful insights & references.
I am enjoying this while chilling on a 5mg diazepam. 😊👍 what a life saver.
My fav channel when it comes to pharmacology , thank you very much
Just love it ❤ thanku for elaborate very briefly ❤
Brilliant and easy to understand explanation. Thank you very much.
Excellent - brief and easy to understand , superb for revision
These lectures legit go through my university lectures slide by slide. fuckin amazing
Thanks for this very detailed one. Im currently taking Clonazepam 1/4 tab morning and evening for my anxiety disorder and panic attack.
Omg thank you so muchh😭😭😭 I swear I'll pass this sem for u
Nicely explained..as if i was having a private tutor... Keep up the good work and a big thanks...
th-cam.com/video/dD5eWuOddXE/w-d-xo.html
Medicinal chemistry of barbiturates
This chanel help me through the Pharmacist lecture😍😍 thank you Ssaem😇😇
Very informative and have always the information I was looking for. Thank you.
Last time of university exam this only help me too much
you are too good in explaining these stuffs, Thank you.
we also use:
- Antihistamines for Situational Insomnia (Hydroxyzine)
- Chloral Hydrate for Short Term Treatment of Insomnia (for extremes of age: Elderly and Children)
- some Antidepressants/Antipsychotics/Beta Receptor Blockers can be used as Anxiolytics
Continue making your videos. They’re really helpful! Thank you...
Best
Your Chanel, your work ... Bruh it's awesome keep it up 💪 👌👌👌
Wooooooow brilliant and stupendous submission. Much love from Ghana 🇬🇭
These drugs are killing us😁
😂☠️
A very little known fact is that benzos are actually even more dangerous to quit than opiates like heroine and fentynal. It’s literally the most dangerous class of drugs to quit. I’m not exactly sure why but it kills lots of people who go cold turkey
How would you best describe a cross tolerance between a benzo like klonopin and a z-drug like ambien. Is there any?
Seriously your channel name Gives a reason why you name it as Speed pharmacology😄😄😄 Thankyou Soo much for this and all other videos 🙇
Damn. Who's on speed 👀
Good teachers can make a dull subject interesting….thanks a lot for the amazing video. Really understood well and hope I can ace my exams!
Thank you very much. Your lectures are the best in TH-cam
NOT HAVE WORDS 🙏🙏 HOW DO I APPRECIATE YOU SIR ❤️❤️❤️❤️❤️❤️❤️❤️LOVE YOU ALOT 🙏🙏
I gain a lot of knowledge from ur videos thanks for videos
Great information, that's clear and understandable! Thank you for sharing!
You Sir are absolutely awesome, Thank You for sharing Your knowledge.
i love your videos..They are informative yet entertaining..I wish you would make videos covering drugs used to treat endocrine disorders such as hypo/hyperthyroidism, acromegaly, cushing and addison's disease
that's really helped me, thank u so much ❤
made easy is an understatement
Such a clear cut short conceptual vedio 👍
Thank you so much, really helped with study,,, much easier to follow in a video than a book
Very well explanation specially animation enhance the explanation. Very helpful for pharmacology exam
Thank you very much for this video. Very educational, easy to understand and learn.
Best explained
Extremely interactive, simple, attractive and easy video ever regarding BZD's Pharmacology. great work. keep it up.
Thank you very much...your videos are very helpful..
This helped me a lot, you explained it perfectly!
I'm curious which software you use to make your videos. Great content by the way!
Thank you so much your videos help a lot 😍
My personal (non-medical professional) opinion is that; society shouldn't have banned GHB as a sleep aid. Prescribing hypnotics doesn't seem to provide deep REM 2 sleep in the same way that GHB did for those with sleep issues.
I would love to hear your thoughts on this. :)
Thank you for this wonderful video. It made me easy to understand the book now... :)
Thank you for making it easy
Most z-drugs do, in fact have considerable anxiolytic properties. I think that’s also why they are so disinhibiting. You can’t bind to the literal benzodiazepine site as an agonist without producing diminished panic and anxiety.
so helpful. thank you
Thank u for the video .........
It is very easy to understand......
Your videos makes pharmacology so easy........
Great as always. Please maximize the use of TH-cam by employing Playlist as well as Community features in ur channel.
Hats off to you sir 🙌🏼
‘Alrpazolam; clonazepam; diazepam; lorazepam; temazepam’
Looks sorta like my Christmas list
i would've said the same a year ago... now i'm just glad to be off that stuff.
It's Satan's gift after you make a deal with him. Then you lose your soul, and then your mind.
Urrghh no way, not anymore
Easy and simply help to clear concept
So well explained
After half an hour i have my pharmacology exams
Finally gathered some confidents
Thankyou:)
Did u pass?
@@armyprincessshell6736 yap i did🤣
The best explanation 🎉 God bless you
Thank you! Please keep making these videos!
So if I take GABA supplements (natural form), it won't affect me negatively, right?
Thank you so much for this video! It was very helpful!
Excellent video!
Thanks you, you saved me from ignorance
"Hey Everybody!!"
"Hey Doctor Nick!!"
I used benzodiazepines as sedatives for years what will happen is they will become a bigger problem than the reason why you started using them in the first place.
If you are using benzodiazepines occasionally and not as a nightly or daily medication . Be careful know the drug you take by taking with your pharmacist who is a chemist 🧪 and knows the effects of medication. Do not tell him why you are taking it this might cause him her to be One sided with what they are telling you. If you ask about a drug that will be the information they give you based on your question and not usage of your medication .
Benzodiazepines are 60 times worse than heroin to withdraw from your first month every gram of fat on your body will be eaten to get the drugs out of it then you start withdrawals and it sucks and you may not be capable of working or functioning normally in society . This does not last forever.
You need to eat right and not abuse yourself.
I know drug addicts and addiction. When a drug addict stops using drugs what happens is your body is trying to heal and you will find that you have more health issues than you believed you had.
When you are poisoning your body on a daily basis your body is fighting for your life and is focused on the abuse it is receiving.
Once your body realizes that it is not being poisoned daily it will now focus on other problems.
As a person who spit my teeth out and tore muscles right off the bone 🦴 because they said they can not help me but I convince them otherwise after the physical damage that was occurring.
With benzodiazepines do your research know what you were doing do not rely on anybody else to tell you as well speak with people who have honestly been through it and not pimping a narrative .
all true
Can confirm, these short term medications with give you long term problems
I'm stiff confused as to how barbiturates attach to the GABAa/b receptor sites, and yet are not supposed to bind to the GABAa/b sites. Aren't they the same place?
I know Buspirone (Buspar) doesn’t work on GABA but it’s still an anxiolytic. Do you cover that in a different video?
As always thank you for the lesson