Absolutely spot on with the exhaustion. it isn't just tiredness; it's a near-total loss of ability: everything just stops working, and rest does not help until it passes. I'm currently fighting to keep my job (and therefore insurance) through all of this.
You’re so right about the word fatigue not really describing what we go through. It’s more like the body shutting down. If you’re well and tired you still have good cognition and can function even after no sleep. With a LC crash all function goes.
Yes, this is more than a word "fatigue". I can't function any when it comes to shut down my body, all day I can't function even my Brain can't function
I want to scream every time I hear myself say “I’m so tired!”, “I’m so very exhausted”, “I’m so weak and have no strength .” because I hear how hallow the words ring compared to how it really feels, the burning hard muscles, joints on fire, chest tight and painful like I’m having a heart attack because to move a limb or try to turn myself , attempt to stand, the 30 ft trip to the bathroom feels like I’m dying, because the feeling of being covered in heavy bags of sand the size of hefty bags weighs on me every day. Fatigue. What a joke. I’ve long said there needs to be a more adequate word for this torture! God, please let there be enough interest now, with all the medical/scientist/wealthy people/celebrities having Long Covid to not ignore post viral illnesses any longer and figure this out, Finally!!! There ARE bio markers and tests that can be done to definitely diagnose Me/CFS, Fibro, Lyme, and more, they are just so expensive they are only used in research. So what we get if we have devoted our lives to raising a family and a community/Church/schools? I tell you what, SSI, $841 a month, if you are lucky. So along with your physics misery you get to worry every day at an ultra high stress level, that if you have ME/CFS is just as bad as physical exertion, so it drives you down even further! By no means am I ever allowed to rest without heavy financial worries, no way can I afford comforting measures, or things to take to try that have helped those with money, like clean, organic food, vitamins/herbs/supplements, and help in the home. It is a disgrace on our country that the disabled are left out, when it comes to deciding where to allocate funds, human connections and help, or even trying to bring current the woefully out of date laws and rules, that haven’t changed since Nixon enacted them. Disgraceful.
Exactly right. It’s way more than being tired. My brain literally stops working and that’s coupled with tingling, vibrating, cold spots, weird visual issues, light sensitivity, sound sensitivity, the list goes on. All I wanna do is lay in my bed with the blinds down.
Thankyou so much, Gez. There is a doctor, Dr Cyanthia Li. Very inspiring for the Long Covid community. She was bed ridden for 3 years with dysautotomia and fibromyalgia. Then she decided to slowly beat her illness and recovered, a wonderful journey of slow healing (the rest and digest mode) about which she wrote in her book- The Brave New Medicine. I have read the book. I Wish you interview her once. It will be extremely inspiring for the Long Covid community.
Thank you Gez, thanks so much . To hear such positivity from the doctor is enormously helpful. Nearly two years for me and I sometimes give up hope. This has helped a lot , thank you again.
Watching this and getting my pieces of the puzzle somewhat sorted out made this 55 year old man cry. I have been on the nicotinic acid protocol since christmas 2020 and it have helped me combat this to a 80% win. Thank you from the bottom of my heart Gez and Ade.
Really amazing work by dr. Wentzel and colleagues. I read the paper and I’m very much surprised that it’s gotten very few citations over the past couple of years. All the things that are happening in the body and this helps make a bit of sense as to the super complicated nature of the illness. Especially given how little is known about the pathogenesis of ME and mechanisms later on in the disease, there are some very useful things in this theory that I have not come across before.
I listened to your videos for over a year now, they've helped me pull out of long haul cv. What worked for me was a low histamine approach alongside anti parasitical herbs since I could not get Iv. Prescribed to me. It made such an initial improvement. Then I juiced a lot last Spring. It have me the vigor and strength to pull out more. With vitamin, mineral and herbs, ginger, etc. I pushed upwards and further along. I'm awaiting cataract surgery as they have grown in quickly. Hoping to return to work soon after that. I had list my husband at the end of 2019,had a stroke in my sleep a week after he died, and then got my initial covid in March of 2020. It wS horrid, blood clots everywhere. Now I watch my diet and get plenty of rest. I take my health seriously, always have. Want to enjoy my Senior years
I have done similar. I did the protocol as soon as I saw it. Tried to get as low histamine intake as possible. Was lucky to get Iv last August 21. Acute symptoms like chest pains, sore throat headaches, palpitations etc. Disappeared on day 3 of the FLCCC protocol. Still had brain fog, tiredness not fatigue, now managing building up my physical strength and lung capacity, and work capacity but making progress every day. I wish you well, sounds like you had a hard time but are determined to get well and happy. Best wishes.
Another great video - So amazing to see progress being made, driven forward by people like Dr Wentzel who throw themselves into the problem for the benefit of us all.
Thank you for your research and hard work. I suffer from a condition called Multiple Chemical Sensitivity and some of it's symptoms seem to coincide with Long Covid symptoms. I am hoping in your search for understanding and a cure of Long Covid that you may be able to provide relief for so many of us that suffer with MCS. It is a completely debilitating, isolating, and life devastating disease with a multitude of horrific symptoms that come on when exposed to any level of chemicals. Personally one of my symptoms is chronic severe vertigo which makes life miserable and intolerable when it's bad. I do hope you can provide relief for many more people than Long Covid patients and will be following your work excitedly!
Heathy food, no suger, no alcohol, extra vitamins, meditation, smoothies, walks, yoga/stretching, resting, set goals, ask for help with household/shopping and try to accept the situation. I'm 13 months not able to work but getting better every month.
When I got sick in early March 2020 and started to have Long Covid symptoms, I spoke to my doctor about my antiphospholipid syndrome possibly being involved with what was going on with me. She completely dismissed me as she didn’t even believe I had ever had Covid because I had “no cough”. She sent me home with a lorazepam prescription for anxiety! 😵💫 So you can imagine how far my jaw dropped around 16:30 into this video. I’m going to send a link for this to my (new) doctor. I kicked the old doctor to curb after she told me all my symptoms were in my head. Thank you for validating what I’ve always believed to be true!
I’ve been taking this stack for almost 3 weeks and feel like I’ve broken the back of my fatigue issue which was my worst symptom, thanks for getting this out there Dr wentzel and gez!
You are an amazing person Gez! As a biologist, this video overlaps with some of the things I figured out on my own. But I certainly didn't figure them all out! The transcript is a godsend! Thank you so much for making that available. I read Dr Terry Wahls book, The Wahls Protocol, as I felt that a lot of my long covid symptoms resembled MS. In her book she recommends consuming organ meats on a regular basis. I have been taking them in pill form for 6 months, in addition to the other things in the stack you recommend. And I think the desiccated organs helped me improve. I'm going to study this chart and see what I can do to fine tune my recovery. BTW, I also take ivermectin once a month. I noted the biggest improvement in my long covid symptoms when I followed the FLCCC guidance for long covid which includes ivermectin. In any case, I am light years away from where I was when I started listening to your videos. I am so much improved, thanks to you. 🤗😘💕👍🤠
Gez, Another amazing video! Makes me wish I saved my AP biology book. Now I remember why us HS science nerds used to say "may all your phosphorilations be chemiosmotic... thank you for all your hard work to research this, document it and disseminate the information. I think it is amazing that you had the energy and motivation to be able to share so much valuable information. Watching your earlier videos, it is encouraging to see how much you have improved health wise.
@0:14 fatigue is not the word. Regular COVID fatigue had me feeling like gravity was pulling on my body where I could barely sit up. The pain and ‘fatigue’ was like nothing I’ve felt before. As much as I knew not to lay around, I had zero energy to even sit up. It was unbelievable.
That is a good point: "chronic fatigue" sounds like "I will clean the basement next week" to those of us who are not ME/CFS sufferers. I didn't have much of a clue until I saw YT videos about people who now required two hours to dress themselves. What really struck me was how many of them had been remarkably athletic before this, particularly the number of runners and marathoners in the Community of the Damned. If not for those videos and particularly this channel I too would probably think it is just a nuisance. Take a day off, get some sleep, and be ready for action the next day. I predict when the pandemic part of COVID is settled and the world tries to get back to normal the public will become aware of the extent of Long Covid... sort of like suddenly noticing the house is infested with crocodiles. Until then there will be madness like "Omicron parties."
@@flagmichael I just want to say thank you for taking the time to learn about the illness and what it's truly like for us. So many just trot along with their misconceptions and make the world a much worse place. People like you are the ones who will make a positive change for everyone🖤
Gez you've been fantastic from the get go with your videos! Thank you for all you do as I'm sure making the videos takes its toll. It's so wonderful and hopeful to see Long Covid dots getting connected by the amazing researchers around the world. It makes me feel hopeful that we'll pull out of this and heal our bodies.
Thanks again Gez for all your hard work. I’ve been taking this stack since this video was released. My only symptoms are brain fog, crushing fatigue and understandable depression. I really wanted to avoid antidepressants so started taking 5HTP 3 days ago. Also I had heard that a teaspoon of food grade Epsom salts in water was helpful. I’ve had no fatigue for 2 days and just wanted to share that in case it might help someone else.
I was in the ICU with COVID in December 2020. To date, I am still experiencing post covid symptoms. The fatigue is terrible. I wake up and can feel close to how I did pre-covid then two hours later I will feel extreme fatigue where I have to lay down. I was a long time runner of over 30 years and can't even run anymore. walking is a chore. Thank you for your informative video.
Thanks for the video, I’m 19 years old male and been suffering for 8 months. And I mean daily suffering. I want to give up but your videos keep my flame alive. I really believe we will have a cure soon and answers. Thank you so much! Btw I’m completely housebound it sucks.
Don’t give up. This problem will be solved. There are simply too many of us to be ignored. Take it day by day and never be afraid to comment just like you did when times get rough. You are not alone.
Dearest one I am soon to be 71 in March and have endured these long haulers symptoms since may of 2020 if I can do this at 70 boy then you can too dearest one ☝️ Self love is self care pacing with patience helps ALOT meditation daily before getting out of bed Which I know can take hours A lot of researching helps because Knowing what’s happening to you and also knowing that you NOT alone Is everything I personally find journaling and drawing illustrations It’s all sitting creating something And soaking hot baths for hours This all Works for me Lots of supplements also And eating healthy But You should do what makesYOU HAPPY 😃 Gaming always worked for my son Jupiter when he was sick as a child Because happiness brings healing 🤗Lotsa Love ❤️ 🧝🏻♀️Lotus 👩🎨
Thank you for all of your amazing work, Gez! I can't tell you how much these videos mean to us. It's such a lonely struggle fighting this disease. Seeing the latest research provides some hope.
You're looking healthier Gez! Hope you're feeling better too. I was wondering if you would consider making a video summarising what you've learnt from all of your conversations with experts and the research you've done? I'm sure I'm not the only one who struggles to keep up with it all. It might also be a useful resource to share with our doctors (unless this resource already exists somewhere else?). My GP says we don't know anything about long covid yet and I'm looking for the best way to show him that that isn't true!
It would be great! In that way we understand better and the doctors as well. They keep on dismissing my daughter and giving her antidepressants what she hasn't taken. My daughter has been suffering from this long Covid fatigue etc. for more than a year. She has been diagnosed with insulin resistance and we hope the diet and supplements work.
Thanks Gez as usual for another great post. Dr Wentzel is a superstar , just into year 3 now and he is the go to guy for my inspiration to just keep on keeping on despite everything. It is the hardest thing ever to get through. So many views and comments on here now, he deserves to be a GIF I think !
Thank you Gez and Dr. Wenzel! The pieces of the jigsaw puzzle are starting to come together. Those dogs need to stop eating the pieces that fall to the floor! I look forward to sharing this article with others. Thank you for all the hard work you have put in with learning all of the meaning and the need for a 3-D whole person approach. (Pieces also occur in the U.S.A.).
Gez, this is awesome to have an update like this come out. Some of us in a long covid Discord have been discussing the emerging trials with BC007 out of Germany. Could you make a video on this/with people from Germany? There's tons of interest in the drug among long haulers, but it's likely to be years before those of us outside of Germany (and people with milder symptoms like myself) can get access. Hoping creating more awareness through channels like your own might help. I should note, niacinamide seemed to cure me for the most part. I'm still dealing with some numbness in my extremities when I run and light PEM, but I'm otherwise doing great.
@@MyMateGeorge non-flush; started out with ~25mg, and basically micro-dosed that throughout the day in ~25mg doses (whenever I felt brain foggy/tired), taking in upwards of 300mg 2-3 months from my 2nd bout with covid. But, as the video suggests, taking the flush variant is better.
Really great interview Gez many thanks. As an NHS Consultant with LC I totally agree the system not set up for a multisystem disease as no dept takes real responsibility. Hopefully getting that message out will lead to better things
My story, 35 years old. I had dizziness for 2-3 months. Weakness and tingling in the left leg and vision problems. Extreme insomnia that still lasts as well as episodes of moderate anxiety. I did an MRI/MRA. Everything is ok about the brain. There is hope for all of us.
I’ve had cfs since 1995, got covid in March 2020 - everything is so much worse now. It really does seem like covid dramatically worsened whatever was already wrong to begin with. I agree with the doc, I think covid and cfs probably have the exact same underlying mechanism
Me too. But sunshine vitamin D3 and K2 and Longvida Tumeric , hyaluronic acid did help. I noticed this virus hates fresh air too. Try Airnergy device , rent one and see if you feel better or hyperbaric oxygen therapy
Diabetics can manage their blood sugar levels much better by going Keto or Carnivore than by injecting synthetic Insulin because the root cause is the cells in the body becoming insulin resistant. When your eating low carbs and healthy saturated animal fats you can reverse insulin resistance and your body will gradually switch from burning carbohydrates to burning fat, the medical experts who present on the TH-cam “Carbs Down Under” channel are calling dementia type 3 diabetes as it’s due to inflammation caused by insulin resistance.
Hi Gaz. Thank goodness for you. I have been ill for over 40 years, with M.E, and gut problems. I had a hysterectomy, then got Epstien Barr. I have battled for all that time with ill health. I have tried every diet, therapy, supplement, and seen every Doctor possible. Then 7 years ago I had breast cancer. I had surgery and radiotherapy. I then ended up with Fibromyalgia. Then 4 years ago I started having bloating cramps and so I. I went to Harley street. Had several tests. I was diagnosed with sibo. And other things. I had Antibiotics twice. Only got worse. Started loosing weight. My G I doctor told me it was IBS. I was sent for a CT scan and a pet Scan. It shows I have breast cancer back, but this time it's spread to both my lungs. I'm not going through treatment again. But on my last hospital visit I got Covid. Now more than 3 months down the line I have long Covid. I watched DR Tina Peers. I beleave I have, Mast Cell Activation Syndrome. I have become allergic to almost every thing that goes into my stomach. I feel so ill all the time now since Covid. My muscles ache all the time, and I'm struggling to eat any thing. My gut us he'll. And I'm totally exhausted all the time. At the moment I have just started Low dose Neltrexon for Cancer. I don't know how I can get to see Doctor Peers. I beleave I may have had this all my 40 years I have been ill. I'm 72 now. And have lost most of my life. Getting no where with GPS. In the UK. I haven't found any one to help me. I have no quality if life. It's not worth living. My words get jumbled up. So sorry for mistakes. Can you offer any advice please. Eileen.
I’m so sorry to hear this Eileen. It’s not really my place to offer advice over and above your doctors, but I would say this one thing: be kind to yourself. Wishing you the very best.
Gez, thank you for another great discussion and discovery on Long Covid. Dr Wenzel is brilliant and motivated and I’m excited to share his findings with my functional md so more healing can begin. This video was better than a box of chocolates for Valentine’s Day 💕💕💕. Coming from a chocoholic, that’s a significant complement 😉. By the way, you look wonderful! Are you following this protocol? Let me know what’s working for you in a DM if you’re comfortable. Best wishes, Gez. You’re a light in the darkness for many. Thank you for your work and commitment to our recovery.
This video is amazing! Can't thank you enough for this info..It's hard to find the micro doses in the protocol though! For instance, I could only find one company selling quercetin anhydrous (Nootropics Depot) and they're 500 mg.
Gez, I was also wondering about these dosages. It’s difficult to find these dosages for these supplements. Is there any leeway to dosage amounts or is it quite strict? I know Dr. Wentzel explains that high doses of quercetin and resveratrol led to nasty side effects. Is there any other wiggle room here? Thank you! 🙏🏼
The interruption to explain some of the cellular processes and vocabulary was helpful. I did not know that this condition was associated with ED. Since having LC, I have gone to have my testosterone checked over this problem. Quite informative interview.
If your Testosterone is low have your cholesterol level checked as well, if it’s low one of its many functions is in the production of Testosterone try going keto or carnivore and see if this helps.
@@mikehale7393 Thank you for this. My testosterone dropped about 80 points since having Long Covid, from about 340 to 260. The endocrinologist didn't seem to think the testosterone was the problem. My cholesterol is still in the upper end of the reference range.
Remember your endocrinologist is only experiances in one 2D layer of the 3D model of your motabalism, we literaly are what we eat 90% of our DNA is in the gut biom.
Thank you so much. This video has been a life-changer for me! The trick was to be really slow and cautious with the Vitamin B, Nicotinic Acid. (This form of Vitamin B seems to be the most important single component.) I am at 50mg/day to keep it at a level where the "flushing" is very occasional and very minor. My Karma tells me that, for seniors, flushing eventually tears us down. Combined with one to two hours of napping, not letting my heart rate go over 95, and never pushing past the point of exhaustion--physically I have improved from a 3/10 to a 6 or 7/10 after about 6 weeks on the regimen. (Memory isn't great, but at least it isnt shutting down anymore!) Again, thanks! Evans
Thank you Gez an Dr. Wentzel! This was one of the most encouraging films! The biochemistry is quite complicated but i look extremely forward to the publication! I believe the good thing with LC is it will have positive impact on medicine and how we approach certain diseases. Very very thankful for what you do!
Thank you so much Gez! Your videos have been so helpful to me over these last, long 22 months. This video in particular was of great interest to me as I have hypermobile Ehlers Danlos, Sjogrens, Lupus and Fibromyalgia. All of these conditions were well under control, in remission until I got covid which caused a horrible autoimmune response that brought them all roaring back with a vengeance. In addition, I've now been diagnosed post covid with hyperadrenergic POTS and MCAS. So your question about the involvement of connective tissue really hit home as I've also seen numerous people in my long covid group now being dx'd with hEDS. I can't wait for Dr W's paper to be published. Thank you for helping to put all the puzzle pieces together for us!
Hi Gez, thank you for doing these videos. Please don’t stop! Lol My tachycardia/pots seems to be improving slowly. Thanks I’m large part to you. Genuinely thought I had no joy in life ahead of me for months but slowly seem to be getting better. OTC antihistamines, Bvits, Vit C and Iron seem to be improving things… that and gradually undertaking more. Thank you so much.
Thanks again for your work. I wish the doctor would have used a microphone like yours. For me with English as a second language it was very difficult to understand him. :(
This is brilliant Gez, so well produced, documented and lucidly explained. Soooo much easier to get a handle on than his pre - print! Dr Wentzel is amazing. I hope his wife forgives him for spending the last year in the lab/with hospital patients, trying to crack the dysfunctional metabolism of LC. 😀His unstoppable enthusiasm and contagious positivity will, I'm sure, deliver on finding effective treatment protocols for LC patients in the near future. NHS, please listen.
Interesting, thank you. This ties into a paper by Matsuyama suggesting that positive feedback between pai-1 and stat3 is responsible for many of the symptoms in acute covid. Pai-1 and hmgb1 act as DAMPs and activate tlr4 which triggers innate activation and cytokine release, and stat3 hyperactivation leads to fibrosis and lymphocytopenia. It feeds back on itself and perhaps becomes chronic. Quinolinic acid/kna, at least in animal models, stimulate pai-1.. and pai-1 is already raised in many metabolic conditions such as insulin resistance...and tlr4 activation stimulates the kynurenine pathway as a homeostatic adaptation in response to infection, especially lps mediated. Would be interesting to see if people noticed improvement with tlr4 inhibition. Hops has an anti-inflammatory effect via this pathway.
Thanks for the great discussion - it gives us hope knowing this important work is being done in the trenches. And it's also great that people like yourself are wrestling with the bigger picture to see how it all fits together. I think the process of 'joining the dots' between micro and macro is the often overlooked aspect that will ultimately reap the most benefits for long haulers. Thanks again.
Apologies if this has already been asked. If - as Dr Wentzel said in your previous video - one can expect to recover in about 1 - 2 weeks on the treatment stack, assuming that the problem mainly concerns NAD and not myopathy - how long would one stay on the treatment thereafter? Thanks for another great video, Gez.
Yes am thinking the same thing Helen. Thanks for posting. Is an expensive stack to purchase. Am just about to start and interested in how long I should continue if my symptoms improve. Adding another thank you for the videos Gez and all the hard work you are putting into collating this research. For the first time I feel hopeful.
Thanks for this interview. Mostly over my head but I'm going to look into the proposed protocol. Was there a clinical trial that cured long haulers or is this protocol still theoretical? Also, I vote for a video on BC007 next!
Every longhauler from 2020 practically did this..I think I'd there was any significant recovery from it there would be "The Stack Pack" long covid recovery pack sold on Amazon by now
Thanks Gez, a very positive interview (albeit quite difficult to keep up with the terminology!) It all stacks up for sure. One this Dr. Wentzel said in passing was that he had found a mechanism to explain the tinnitus that many long-haulers suffer. Can you point me to where I can find this? Thanks! Keep up the great work and get better yourself.
Thank you as always for all your hard work . I must admit this particular podcast was hard for me to take in whether that's my covid brain or just me - probably just me 🙄👩🏼🐾👍
With so many of us experiencing constant and sometimes debilitating tinnitus, I was curious if this has been addressed in any of your interviews? I can press on the nerve bundle behind my ear and it almost goes away. It makes me want to dig into my skull there and pull out the nerve bundle, lol! Just kidding, I wouldn't do that. It is the one thing that is constant and I can't get rid of completely. Thank you for all you do, this channel has been so enlightening and helpful.
There is hope after 2 years my symptoms thanks God are improving specially since the last 6 months . I even tried to stay home for 2 weeks to see if I get a relapse and didn't happen unlike a year and half ago
I have had Long COVID since April 2021. Included a TIA event while driving the totaled my car. Have been extremely concerned about controlling blood clots, as well as CFS, loss of sense of smell, tinnitus and loss of stamina. Was very interested in this video and since I already taking most of the suggested regimen, I decided to take 20mg of nicotinic acid along with 200mg L-tryptophan daily at bedtime. I was surprised to see a noticeable improvement in only 2-3 days. After 2 weeks of this regimen, my stamina is greatly improved and I now do routine maintenance chores around the house including working on my car and wood working. I may get tired after several hours of work but recover over night. Before starting this regimen, a fourth of this much work would have taken me out for several days. Extremely happy with these results. Now wondering how long to continue this supplementation. If depletion of NAD+ was the cause, is continued supplementation required after NAD+ levels are restored? If the recycling of NAD+ has been affected, continued supplementation may be required. Any anecdotal information available here?
Pre med here, agree w all u r doing/infected same time/autoimmune/vac injured/long Lyme, etc.. go on De Mandell, free, sells nothing/likes serrateoase.. whatever I am on(natural), I go off it periodically and do 48 hr intermittent fasting.. green tea no good for histamines, mast cell activation, tu / best to all🙏🌷♥️🕊️
@@RUNDMC1 Gez how are you doing now? Did you get any benefit from Dr Wentzel's protocol? I think I am starting to. I think the niacin helps as well as the reduction in exertion.
I must have listened to this 50 times. It’s totally changed my life. I’m feeling 97% better thanks to Niacin. Eternally grateful to Dr Wentzel et you Gez 🙏🏽
@@nchoulagh the crushing fatigue and the walking waist deep in mud aching tiredness in my legs… I still have mottled skin at different times of the day but honestly this has made a big difference (plus I have MCAS and for that I’m on a H1 and H2 once a day). Still have brain fog though
@@aineotoole3686 i started off with 30mg p/d and slowly, slowly worked up to now 80mg 3 x p/d.. the Niacin I bought is 10mg tablets so i can easily dose as I want… Aiming for 100mg 3 x p/d.. recently been feeling the heavy legs again (but still no fatigue). Feel this higher dose is working on a deeper level and have good days and more challenging days where symptoms resurface.
Thanks for the great interview. A couple of thoughts; I believe apigenin has also been found to drive down CD38 and is more bioavailable than quercetin (I take both). Its not surprisingly that low NAD might be linked to more niacin flush as I believe the flush has to do with systemic inflammation. Finally, the more recent studies do not seem to support resveratrol as a sirt activator (see Dr. Brad Stanfield). I'm currently taking niacin and NR.
@@doraprinsloo9468 anyone with MTHFR mutation cannot take folic acid. I take B minus and B12 and folate. About 50% of people have that genetic variation.
How do we find his papers? My doctors will not watch the video? This guy is spot on for my daughter. Dec 2020 long covid 19 years old 3 degree black belt. Suffering now.
Thank you so much for sharing this info. Having the flushing kind of niacin gave me relief for the first time in weeks after just a few doses. It felt like my skin was tingling with hot sauce fire for a minute but then was like the cloak of fatigue lifted and I had so much more mental clarity. I’m not feeling anywhere near 100% but felt like I went from feeling 10% to 50% with this one change alone. Thank you!
As someone who has experienced varying frequencies and intensities of cfs/me since having mono in 1968, the absolutely disabling exhaustion I have been experiencing with long-coved since initially having covid in October of 2020, is in a class by itself. I have just begun self-medication with Truniagen under the data-supported hypotheses that nad+ is depleted by covid-19, as well as in cfs/me, and chronic kidney disease, which I have had for 20 years, and autoimmune connective disease diagnose 25 years ago.. Pray this will improve nad+ production, and utilization, and Sirt 1 activation..
Gez, your efforts are priceless! Thank you so much for your videos. I'm 12 months with LC now and i would like to know how do you feel after your "experiment in the Alps". Are you probing with more 'sport'? Greetings from Spain ❤️
Thank you very much for this video. Dr. Wentzel laid out a perfect puzzle of possibilities. The problem is, not even specialists would agree to test for these indicators. May I ask Dr. Wentzel if he investigated phytanic acid, x-linked "VLCFA" (very long chain fatty acids) as another indicator or even as a marker?
Thank you so much Gez! I’ve just discovered your videos (way too late in the game but nonetheless incredibly helpful) and I love how easily you explain everything and interact with these amazing doctors. With approval of my many doctors, I’m going to start this protocol. I’m sorry if this question has already been answered, but is there less effectiveness to taking “flush-free niacin” with inositol hexaniacinate rather than just niacin? I know that Dr. Wentzel explained the flush is important for the NAD enzyme, so I’m wondering if I should just take that? Thank you so much! I greatly appreciate what you do! 🙏🏼
Hi Jocelyn, thanks for the comment! The flushing variety does seem to be more effective so if you can tolerate it it’s worth having. If you don’t tolerate it then non-flush will still be OK :)
Excellent video! Does anyone know if Wentzel is in touch with Ron Davis? Davis has been studying this exact pathway, and is currently trialling off label use of FDA approved medications to get at it.
I did not know about him until you mentioned him here. I looked him up and quite a story with his son, but could be a blessing for all of us as he seems like a top level researcher. I sure hope he solves for all of us.
Thanks, Gez. A couple of questions: 1. Why (specifically) is it important to not go above that maximum heart rate? Is it to prevent the post-exertional malaise / symptom triggers of an over inflammatory response and/or is it dangerous onto itself, as one might consider with a peri or myocarditis diagnosis? (I still feel instinctively very cautious about increasing my heart rate, and mostly just do daily walks or gentle stretching or very light dancing). 2. Do you think we're likely going to just have to accept permanent lifestyle changes, and not going back to our (for many of us) prior athletic norms? 3. It seems true, anecdotally, that very few of us are experiencing a full 100% return to baseline, at least at this 2 years and under point. Did you understand this doctor to be saying that what we're looking at is management of auto-immune conditions and/or optimizing recovery to as fulsome a point as we can? (Sorry, couldn't quite get through all the dense biological / chemistry mapping!) I mean, was he saying, many are getting to 60% recovery and some all the way to 97% but almost no one to 100%. Did I get that right? 4. I look forward to you distilling your summaries of knowledge into lay person treatment recommendations, especially any updates or ideas you have about either this root-cause support and/or key tips for treatment for any particular symptom clusters. 5. I also remain truly curious and hopeful for your thoughts (if any) or handling future Covid reinfections and/or endless boosters, as it feels like the world is opening up again and it seems almost certain many or most of us will be exposed again at some point or another. I'd love to hear what you might do (if anything) in that instance, for yourself, to give us food for thought, too. As always, thank you very much.
Gez has a lot of videos here on the practical side of dealing with LC. They are all worth checking out. Most rightly have a theme of not overdoing it, but watch "The Great Experiment: Can Activity Play a Role in Long Covid Recovery?" th-cam.com/video/UCJhYAQ6aGk/w-d-xo.html
Hi Nicola - gosh, a lot here to address! 1) The HR limit is to manage the risk of PEM. Intensity of activity seems to be the major driver of it so by limiting HR we minimise the risks 2) Honestly at this point I don’t know. I think a great many of us won’t get back to where we were before covid, but if we can still live a full and rewarding life that’s what we should focus on, difficult as it may be! 3) Dr W is saying that he has seen long haulers make full recoveries. From my part I don’t know that many of them - most people I know who have recovered are getting back to 90% perhaps. I have known a couple who thought they’d made 100% then relapsed. 4) It’s coming! Announcement in the next couple of weeks :) 5) This is a f***ing minefield. Massive catch-22 re boosters. I think all you can do if you get reinfected is just to do everything right we didn’t do the first time! ie massive rest, get on the stack if not already, take anti histamines, aspirin and if you can get other anti-coags then those too. Hope you’re doing well!
Ive been having tension headaches , migranes , eye pain and chest pain for 6 months after contacting covid. All doctors are gas lighting me telling me its anxiety. This channel is the only thing helping me
Thank you Gez for all you’re doing regarding long covid and all those suffering (a year now for me)! It sometimes feels like there’s little chance or hope of getting over this. However seeing these videos and pathways to what will hopefully be a full recovery is brilliant. Can I ask if regular drops in blood sugar/ hypoglycaemia is also linked to long covid?
@@RUNDMC1 Ah ok. I have that going on as well but never high blood sugar. Kind of hoping it’s linked rather than a separate issue. Thanks for your reply.
Many many thanks for this. Really great knowledge, that we don't get through public health. Thanks for being a bit of an angel of necessary knowledge. Greetings from Berlin!
Thank you for these videos. However, the niacin/C/D/zinc/selenium/quercetin helped at first, but after about 5 days I started getting the same old symptoms back again- headache, stiff neck, burning eyes, brain fog, GI disturbance. Not really sure what to think. When I take benadryl my smell comes back briefly. When I exercise too hard, within a day or two all these symptoms come back hard. Tried many supplements, probiotics, etc... Still looking for a cure for Long COVID. I feel like you are getting closer but what is missing from these interviews is the origin of the problem. For example, WHY does covid cause niacin depletion? Or WHY do covid antigens cause polarized long-lived inflammatory monocytes? Something is missing to unite all of these theories together, the original cause of the damage from COVID. I am still not seeing that, at least not consistently for all long haul patients. It seems that some people are helped by some treatments, but there are definitely plenty of us still not getting better.
It sounds like Mestinon should help with POTS according to this theory - interestingly Mestinon has been found to be helpful for many people with POTS. Mestinon is a cholinesterase inhibitor, it increases the amount of acetylcholine at the synaptic junction.
I’ve worked up slowly to 2 x 50mg Niacin p/day with the rest of the stack and honestly I feel like it’s helping, less exhausted, can do more physical work without getting totally wiped out and less circulation problems in my legs which was the worst 🙏🏽 Have you felt a difference Gez and what’s the optimal daily dose theoretically? Has Dr Wentzel’s preprint been published? Why isn’t there more media coverage about his work???
Do we know how long this will last . Will we get better I have come around alot but am still always tired if I train I end up in bed for days 16 months never once felt me old self
I had long covid after early infection march 2020. Am better now, i was very careful when introducing exercise in my case gardening (my job) dog walking. I would work 2 hrs then rest all afternoon at first. Slowly built it up over 2021. I didnt take anything apart from ibruferon occadionally and vit D which i think helps greatly. Hope you get better soon.
Hi Gez, Thanks so much for your content as usual! I feel very grateful that I am at the point now where I feel largely back to normal after 16 months, I can exercise again without any serious repercussions and can live a pretty normal life. However, I still generally feel a bit foggy and lack energy and just don't feel quite 100%. I wondered if you had any insights into your experience with aphresis - I've been offered a slot and am debating whether it would benefit me and my symptoms. Would love to hear any insights from you or anyone else with experience!
Thank you for all the videos you’ve posted. My very sporty daughter aged 15 has developed Orthostatic Intolerance since contracting Covid. She also has Covid Toes, or Erythromalagia. fatigue, constant headache (band like), brainfog extreme, eye focus problems too when headache is bad. Looking at the diagram is seems to all point to: kynurenic acid and it’s impact on the receptors. How best to fix? Thanks for sharing the protocol. She’s on several supplements, but not Niacin!, histamines, anti coagulation, lots of water, lots of rest. Five months in now.
Love this - but wondering why thiamine is left out? It's an important coenzyme in the Krebs cycle. Adding it to my stack made me improve hugely on so many things that were still persistent
Huge info. Why does LC happen to some people and not others though? Almost everybody I know doesn't believe it can happen for years out and didn't experience it when they got covid.
It's likely due to different susceptibilities, both genetic and lifestyle. My theory is people with highly sensitive immune systems but weaker repair systems, young men and child-bearing age women, have their bodies "freak out" during infection and cause a bunch of damage, and the body is unable to repair itself properly without a serious boost. Children's bodies can repair easily, and older people as well as less healthy people actually get less damage from their own body because its weaker firepower means less collateral damage. I had an incredibly strong immune system as a young man, hadn't had more than a head cold in five years, and long covid has absolutely wiped me. Meanwhile my obese parents seem to be completely fine.
Great video once again Gez! I have a question for you about the neurological symptoms that lie under the umbrella term brain fog. Does the data that we have today indicate that: - It is temporary - That permanent damage have been caused - (Or worst of all) that our cognitive abilities will continue to deteriorate over time?
I agree with Gez. Neuroscience has shown the brain to be neuroplastic - the ability of neural networks in the brain to change through growth and reorganisation. I believe we absolutely can “retrain” our neurological pathways and improve brain function with corrective actions. Dr Andrew Huberman (neurobiologist) has some great content on this. I also think Dr David Siclair’s research is also important for cellular regeneration etc. The scientific community are making enormous strides in putting together many of the puzzle pieces. What we need now is one body/organisation/NPO to bring it all together (like Gez is doing) for all of us to benefit from.
My Omicron long haul is happily just paralyzed both my thumbs, the left one is worse and is swollen. It comes and goes, fasting helps but I call it funky thumbs and I am happy is it not funky anything else, but I like my thumbs and I'm confident some day they will return to a less paralyzed state. Other long hauls were far more unplesant and the recurring feeling of being near death was far too familiar to them all.
Gez have you got an update for Dr Wentzels new paper, the glimpses & methodology were very interesting, I keep looking to see if it’s published. I’m almost 12 months on vacc damaged with AZ, thanks
How can we find his paper? My doctors apparently don’t like videos. This doctor is spot on. My daughter has pots/long covid since dec 2020. Keep the intel rolling. Awesome job.
Doing some great work Gez, thanks for that! I have some questions about the dosage of some supplements. Some speaks for itself, but others are not that clear for me (and my brainfog) The quercetine is a lot less than the 'first stack' where 3x 500mg was prescribed. Is this due to the fact that now is spoken about quercetine anhydrous? I am now using di-hydrate The methylcobalamin I find the most is about 1000mcg, that's way too much in this case? Where does AAC at selenium and zinc stands for? The dosages of selenium I find the most in supplements are about 100mcg, so a dosage will be 10-30 pills? I think I am overlooking some details..
Absolutely spot on with the exhaustion. it isn't just tiredness; it's a near-total loss of ability: everything just stops working, and rest does not help until it passes.
I'm currently fighting to keep my job (and therefore insurance) through all of this.
You’re so right about the word fatigue not really describing what we go through. It’s more like the body shutting down. If you’re well and tired you still have good cognition and can function even after no sleep. With a LC crash all function goes.
No truer words have ever been spoken. People who dont have LC have literally No Idea what this fatigue feels like.
Yes, this is more than a word "fatigue". I can't function any when it comes to shut down my body, all day I can't function even my Brain can't function
I want to scream every time I hear myself say “I’m so tired!”, “I’m so very exhausted”, “I’m so weak and have no strength .” because I hear how hallow the words ring compared to how it really feels, the burning hard muscles, joints on fire, chest tight and painful like I’m having a heart attack because to move a limb or try to turn myself , attempt to stand, the 30 ft trip to the bathroom feels like I’m dying, because the feeling of being covered in heavy bags of sand the size of hefty bags weighs on me every day. Fatigue. What a joke. I’ve long said there needs to be a more adequate word for this torture! God, please let there be enough interest now, with all the medical/scientist/wealthy people/celebrities having Long Covid to not ignore post viral illnesses any longer and figure this out, Finally!!! There ARE bio markers and tests that can be done to definitely diagnose Me/CFS, Fibro, Lyme, and more, they are just so expensive they are only used in research. So what we get if we have devoted our lives to raising a family and a community/Church/schools? I tell you what, SSI, $841 a month, if you are lucky. So along with your physics misery you get to worry every day at an ultra high stress level, that if you have ME/CFS is just as bad as physical exertion, so it drives you down even further! By no means am I ever allowed to rest without heavy financial worries, no way can I afford comforting measures, or things to take to try that have helped those with money, like clean, organic food, vitamins/herbs/supplements, and help in the home. It is a disgrace on our country that the disabled are left out, when it comes to deciding where to allocate funds, human connections and help, or even trying to bring current the woefully out of date laws and rules, that haven’t changed since Nixon enacted them. Disgraceful.
Exactly right. It’s way more than being tired.
My brain literally stops working and that’s coupled with tingling, vibrating, cold spots, weird visual issues, light sensitivity, sound sensitivity, the list goes on.
All I wanna do is lay in my bed with the blinds down.
Why not water board the bat lady, make the witch squeal..
THIS channel should be a go-to for the NHS.
Thankyou so much, Gez.
There is a doctor, Dr Cyanthia Li. Very inspiring for the Long Covid community. She was bed ridden for 3 years with dysautotomia and fibromyalgia. Then she decided to slowly beat her illness and recovered, a wonderful journey of slow healing (the rest and digest mode) about which she wrote in her book- The Brave New Medicine. I have read the book. I Wish you interview her once. It will be extremely inspiring for the Long Covid community.
Thank you Gez, thanks so much . To hear such positivity from the doctor is enormously helpful. Nearly two years for me and I sometimes give up hope. This has helped a lot , thank you again.
My pleasure Stuart!
@@RUNDMC1 Don't give up hope, taking the Nicotinic acid, and the rest, has made all the difference to me. I'm not quite 100% better but I'm close.
Thank you for the brilliant 3D analogy@@RUNDMC1
@@wendylorimer5663 Did you start showing improvement within days or several weeks?
@@wendylorimer5663 out of interest where did you get the nicotinic acid from? Which brand? Thanks! ☺️
Gez. You are a modern day hero. Thank you for sticking with this!
Watching this and getting my pieces of the puzzle somewhat sorted out made this 55 year old man cry.
I have been on the nicotinic acid protocol since christmas 2020 and it have helped me combat this to a 80% win. Thank you from the bottom of my heart Gez and Ade.
So glad to hear it’s made a difference for you 😊
And nothing wrong with being a grown man crying - I do it all the time!
@DuskTropic how long was it in the Niacin before you felt improvement? Which protocol are you following? And what dose care you currently on? Thanks
@@browneyedgirlFL67 It took about two weeks before I felt any improvement. The effect builds up over time. I am on 500 mg/day (nicotinic acid)
@Maadj Gumar No it is a B-vitamin. B3
Do you use Flushing or Non-Flushing (What Brand are you using?)?
Really amazing work by dr. Wentzel and colleagues. I read the paper and I’m very much surprised that it’s gotten very few citations over the past couple of years. All the things that are happening in the body and this helps make a bit of sense as to the super complicated nature of the illness. Especially given how little is known about the pathogenesis of ME and mechanisms later on in the disease, there are some very useful things in this theory that I have not come across before.
I listened to your videos for over a year now, they've helped me pull out of long haul cv.
What worked for me was a low histamine approach alongside anti parasitical herbs since I could not get Iv. Prescribed to me.
It made such an initial improvement. Then I juiced a lot last Spring. It have me the vigor and strength to pull out more. With vitamin, mineral and herbs, ginger, etc. I pushed upwards and further along. I'm awaiting cataract surgery as they have grown in quickly.
Hoping to return to work soon after that.
I had list my husband at the end of 2019,had a stroke in my sleep a week after he died, and then got my initial covid in March of 2020. It wS horrid, blood clots everywhere.
Now I watch my diet and get plenty of rest. I take my health seriously, always have. Want to enjoy my Senior years
So glad to hear you’re doing better!
@RUN-DMC / Gez Medinger thank you for your videos. I attribute my health to your information. Please continue to help us please. Ty.
I have done similar. I did the protocol as soon as I saw it. Tried to get as low histamine intake as possible. Was lucky to get Iv last August 21. Acute symptoms like chest pains, sore throat headaches, palpitations etc. Disappeared on day 3 of the FLCCC protocol. Still had brain fog, tiredness not fatigue, now managing building up my physical strength and lung capacity, and work capacity but making progress every day. I wish you well, sounds like you had a hard time but are determined to get well and happy. Best wishes.
Another great video - So amazing to see progress being made, driven forward by people like Dr Wentzel who throw themselves into the problem for the benefit of us all.
Thank you for your research and hard work. I suffer from a condition called Multiple Chemical Sensitivity and some of it's symptoms seem to coincide with Long Covid symptoms. I am hoping in your search for understanding and a cure of Long Covid that you may be able to provide relief for so many of us that suffer with MCS. It is a completely debilitating, isolating, and life devastating disease with a multitude of horrific symptoms that come on when exposed to any level of chemicals. Personally one of my symptoms is chronic severe vertigo which makes life miserable and intolerable when it's bad. I do hope you can provide relief for many more people than Long Covid patients and will be following your work excitedly!
Heathy food, no suger, no alcohol, extra vitamins, meditation, smoothies, walks, yoga/stretching, resting, set goals, ask for help with household/shopping and try to accept the situation. I'm 13 months not able to work but getting better every month.
Thank you for making more films about this subject Gez. Your work are deeply appreciated and extremely important.
Thank you!
When I got sick in early March 2020 and started to have Long Covid symptoms, I spoke to my doctor about my antiphospholipid syndrome possibly being involved with what was going on with me. She completely dismissed me as she didn’t even believe I had ever had Covid because I had “no cough”. She sent me home with a lorazepam prescription for anxiety! 😵💫 So you can imagine how far my jaw dropped around 16:30 into this video. I’m going to send a link for this to my (new) doctor. I kicked the old doctor to curb after she told me all my symptoms were in my head. Thank you for validating what I’ve always believed to be true!
I know exactly what you mean! Sometimes I think I should be wearing the doctor’s credentials and they should go back to school. 🤦🏻♀️
Good for you!!! 👍👍👍💯
I'm beginning to wonder if Doctor's are being told to dismiss as many as poy.
@@susanwright1999 it's really sad if most are chalking it up to anxiety!!! 😤😞
@@susanwright1999 you may be right about that!!!
I’ve been taking this stack for almost 3 weeks and feel like I’ve broken the back of my fatigue issue which was my worst symptom, thanks for getting this out there Dr wentzel and gez!
Great news! How are you doing now?
You are an amazing person Gez!
As a biologist, this video overlaps with some of the things I figured out on my own. But I certainly didn't figure them all out! The transcript is a godsend! Thank you so much for making that available.
I read Dr Terry Wahls book, The Wahls Protocol, as I felt that a lot of my long covid symptoms resembled MS. In her book she recommends consuming organ meats on a regular basis. I have been taking them in pill form for 6 months, in addition to the other things in the stack you recommend. And I think the desiccated organs helped me improve.
I'm going to study this chart and see what I can do to fine tune my recovery.
BTW, I also take ivermectin once a month. I noted the biggest improvement in my long covid symptoms when I followed the FLCCC guidance for long covid which includes ivermectin.
In any case, I am light years away from where I was when I started listening to your videos. I am so much improved, thanks to you. 🤗😘💕👍🤠
So glad you’re doing better Laura, and thanks for the support!
I have a had good luck with ivermectin as well thanks for tip of taking once month is that the one day dose or are you repeating the five day dose?
Gez, Another amazing video! Makes me wish I saved my AP biology book. Now I remember why us HS science nerds used to say "may all your phosphorilations be chemiosmotic... thank you for all your hard work to research this, document it and disseminate the information. I think it is amazing that you had the energy and motivation to be able to share so much valuable information. Watching your earlier videos, it is encouraging to see how much you have improved health wise.
Thank you Katrina! Best of luck to you in your recovery :)
@0:14 fatigue is not the word. Regular COVID fatigue had me feeling like gravity was pulling on my body where I could barely sit up. The pain and ‘fatigue’ was like nothing I’ve felt before. As much as I knew not to lay around, I had zero energy to even sit up. It was unbelievable.
That is a good point: "chronic fatigue" sounds like "I will clean the basement next week" to those of us who are not ME/CFS sufferers. I didn't have much of a clue until I saw YT videos about people who now required two hours to dress themselves. What really struck me was how many of them had been remarkably athletic before this, particularly the number of runners and marathoners in the Community of the Damned. If not for those videos and particularly this channel I too would probably think it is just a nuisance. Take a day off, get some sleep, and be ready for action the next day.
I predict when the pandemic part of COVID is settled and the world tries to get back to normal the public will become aware of the extent of Long Covid... sort of like suddenly noticing the house is infested with crocodiles. Until then there will be madness like "Omicron parties."
@@flagmichael I just want to say thank you for taking the time to learn about the illness and what it's truly like for us. So many just trot along with their misconceptions and make the world a much worse place. People like you are the ones who will make a positive change for everyone🖤
Exactly. I feel like I have flu levels of fatigue, over a year. There is no option to push through it. It is not like a healthy fatigue at all.
Gez you've been fantastic from the get go with your videos! Thank you for all you do as I'm sure making the videos takes its toll. It's so wonderful and hopeful to see Long Covid dots getting connected by the amazing researchers around the world. It makes me feel hopeful that we'll pull out of this and heal our bodies.
Thank you Nicole!
Thanks again Gez for all your hard work. I’ve been taking this stack since this video was released. My only symptoms are brain fog, crushing fatigue and understandable depression. I really wanted to avoid antidepressants so started taking 5HTP 3 days ago. Also I had heard that a teaspoon of food grade Epsom salts in water was helpful. I’ve had no fatigue for 2 days and just wanted to share that in case it might help someone else.
😊
I was in the ICU with COVID in December 2020. To date, I am still experiencing post covid symptoms. The fatigue is terrible. I wake up and can feel close to how I did pre-covid then two hours later I will feel extreme fatigue where I have to lay down. I was a long time runner of over 30 years and can't even run anymore. walking is a chore. Thank you for your informative video.
I had Covid in Dec 2020 also and still experiencing severe fatigue and sometimes weakness.
How are u now?
Thanks for the video, I’m 19 years old male and been suffering for 8 months. And I mean daily suffering. I want to give up but your videos keep my flame alive. I really believe we will have a cure soon and answers. Thank you so much! Btw I’m completely housebound it sucks.
Don’t give up. This problem will be solved. There are simply too many of us to be ignored. Take it day by day and never be afraid to comment just like you did when times get rough. You are not alone.
So sorry to hear this. I am 7 months in. It sucks.
So sorry to hear this - keep pacing! And try Niacin :)
@@AlbaLynxQueen same here
Dearest one
I am soon to be 71 in March
and have endured these long haulers
symptoms since may of 2020
if I can do this at 70 boy
then you can too
dearest one ☝️
Self love is self care
pacing with patience helps ALOT
meditation daily before getting out of bed
Which I know can take hours
A lot of researching helps because
Knowing what’s happening to you
and also knowing
that you NOT alone
Is everything
I personally find
journaling and drawing illustrations
It’s all sitting creating something
And soaking hot baths for hours
This all Works for me
Lots of supplements also
And eating healthy
But You should do
what makesYOU HAPPY 😃
Gaming always worked
for my son Jupiter
when he was sick as a child
Because
happiness brings healing
🤗Lotsa Love ❤️
🧝🏻♀️Lotus 👩🎨
Another corker! You are real star.Thank you for shining a light on the emerging optimism of understanding our debilitating condition
Thank you for all of your amazing work, Gez! I can't tell you how much these videos mean to us. It's such a lonely struggle fighting this disease. Seeing the latest research provides some hope.
You're looking healthier Gez! Hope you're feeling better too.
I was wondering if you would consider making a video summarising what you've learnt from all of your conversations with experts and the research you've done? I'm sure I'm not the only one who struggles to keep up with it all. It might also be a useful resource to share with our doctors (unless this resource already exists somewhere else?). My GP says we don't know anything about long covid yet and I'm looking for the best way to show him that that isn't true!
I’ll have something to talk about on this front soon!
@@RUNDMC1Llook forward to it. Thanks for doing what you do so well.
It would be great! In that way we understand better and the doctors as well. They keep on dismissing my daughter and giving her antidepressants what she hasn't taken. My daughter has been suffering from this long Covid fatigue etc. for more than a year. She has been diagnosed with insulin resistance and we hope the diet and supplements work.
Thanks Gez as usual for another great post. Dr Wentzel is a superstar , just into year 3 now and he is the go to guy for my inspiration to just keep on keeping on despite everything. It is the hardest thing ever to get through. So many views and comments on here now, he deserves to be a GIF I think !
Thank you Tanya!
Thank you Gez and Dr. Wenzel! The pieces of the jigsaw puzzle are starting to come together. Those dogs need to stop eating the pieces that fall to the floor! I look forward to sharing this article with others. Thank you for all the hard work you have put in with learning all of the meaning and the need for a 3-D whole person approach. (Pieces also occur in the U.S.A.).
Thank you Leslie!
Gez, this is awesome to have an update like this come out. Some of us in a long covid Discord have been discussing the emerging trials with BC007 out of Germany. Could you make a video on this/with people from Germany? There's tons of interest in the drug among long haulers, but it's likely to be years before those of us outside of Germany (and people with milder symptoms like myself) can get access. Hoping creating more awareness through channels like your own might help.
I should note, niacinamide seemed to cure me for the most part. I'm still dealing with some numbness in my extremities when I run and light PEM, but I'm otherwise doing great.
Hi Dan - trying to set something up with Berlin Cures, leave it with me
How much niacin were you taking? Flush/non-flush?
@@MyMateGeorge flush is better, I would start off low then build up, I can't remember dose I think Gez talks about dose in previous vids
@@MyMateGeorge non-flush; started out with ~25mg, and basically micro-dosed that throughout the day in ~25mg doses (whenever I felt brain foggy/tired), taking in upwards of 300mg 2-3 months from my 2nd bout with covid. But, as the video suggests, taking the flush variant is better.
@@FPproductionz Thanks, Dan!
Really great interview Gez many thanks. As an NHS Consultant with LC I totally agree the system not set up for a multisystem disease as no dept takes real responsibility. Hopefully getting that message out will lead to better things
Hope will help those of us with ME from other viruses as well.
Always here to help.
I hope so too!
My story, 35 years old. I had dizziness for 2-3 months. Weakness and tingling in the left leg and vision problems. Extreme insomnia that still lasts as well as episodes of moderate anxiety. I did an MRI/MRA. Everything is ok about the brain. There is hope for all of us.
You feel better now?
I’ve had cfs since 1995, got covid in March 2020 - everything is so much worse now. It really does seem like covid dramatically worsened whatever was already wrong to begin with. I agree with the doc, I think covid and cfs probably have the exact same underlying mechanism
Me too. But sunshine vitamin D3 and K2 and Longvida Tumeric , hyaluronic acid did help. I noticed this virus hates fresh air too. Try Airnergy device , rent one and see if you feel better or hyperbaric oxygen therapy
Diabetics can manage their blood sugar levels much better by going Keto or Carnivore than by injecting synthetic Insulin because the root cause is the cells in the body becoming insulin resistant.
When your eating low carbs and healthy saturated animal fats you can reverse insulin resistance and your body will gradually switch from burning carbohydrates to burning fat, the medical experts who present on the TH-cam “Carbs Down Under” channel are calling dementia type 3 diabetes as it’s due to inflammation caused by insulin resistance.
Hope for a jongy?
Hi Gaz. Thank goodness for you. I have been ill for over 40 years, with M.E, and gut problems. I had a hysterectomy, then got Epstien Barr. I have battled for all that time with ill health. I have tried every diet, therapy, supplement, and seen every Doctor possible. Then 7 years ago I had breast cancer. I had surgery and radiotherapy. I then ended up with Fibromyalgia. Then 4 years ago I started having bloating cramps and so I. I went to Harley street. Had several tests. I was diagnosed with sibo. And other things. I had Antibiotics twice. Only got worse. Started loosing weight. My G I doctor told me it was IBS. I was sent for a CT scan and a pet Scan. It shows I have breast cancer back, but this time it's spread to both my lungs. I'm not going through treatment again. But on my last hospital visit I got Covid. Now more than 3 months down the line I have long Covid. I watched DR Tina Peers. I beleave I have, Mast Cell Activation Syndrome. I have become allergic to almost every thing that goes into my stomach. I feel so ill all the time now since Covid. My muscles ache all the time, and I'm struggling to eat any thing. My gut us he'll. And I'm totally exhausted all the time. At the moment I have just started Low dose Neltrexon for Cancer. I don't know how I can get to see Doctor Peers. I beleave I may have had this all my 40 years I have been ill. I'm 72 now. And have lost most of my life. Getting no where with GPS. In the UK. I haven't found any one to help me. I have no quality if life. It's not worth living. My words get jumbled up. So sorry for mistakes. Can you offer any advice please. Eileen.
I’m so sorry to hear this Eileen. It’s not really my place to offer advice over and above your doctors, but I would say this one thing: be kind to yourself. Wishing you the very best.
Gez, thank you for another great discussion and discovery on Long Covid. Dr Wenzel is brilliant and motivated and I’m excited to share his findings with my functional md so more healing can begin. This video was better than a box of chocolates for Valentine’s Day 💕💕💕. Coming from a chocoholic, that’s a significant complement 😉. By the way, you look wonderful! Are you following this protocol? Let me know what’s working for you in a DM if you’re comfortable. Best wishes, Gez. You’re a light in the darkness for many. Thank you for your work and commitment to our recovery.
Thank you ZZ! Yes I’m following this protocol.
This video is amazing! Can't thank you enough for this info..It's hard to find the micro doses in the protocol though! For instance, I could only find one company selling quercetin anhydrous (Nootropics Depot) and they're 500 mg.
@@mike_zander Quercetin dose should be in mg!
Gez, I was also wondering about these dosages. It’s difficult to find these dosages for these supplements. Is there any leeway to dosage amounts or is it quite strict? I know Dr. Wentzel explains that high doses of quercetin and resveratrol led to nasty side effects. Is there any other wiggle room here? Thank you! 🙏🏼
The interruption to explain some of the cellular processes and vocabulary was helpful. I did not know that this condition was associated with ED. Since having LC, I have gone to have my testosterone checked over this problem. Quite informative interview.
If your Testosterone is low have your cholesterol level checked as well, if it’s low one of its many functions is in the production of Testosterone try going keto or carnivore and see if this helps.
@@mikehale7393 Thank you for this. My testosterone dropped about 80 points since having Long Covid, from about 340 to 260. The endocrinologist didn't seem to think the testosterone was the problem. My cholesterol is still in the upper end of the reference range.
Remember your endocrinologist is only experiances in one 2D layer of the 3D model of your motabalism, we literaly are what we eat 90% of our DNA is in the gut biom.
Thank you so much. This video has been a life-changer for me!
The trick was to be really slow and cautious with the Vitamin B, Nicotinic Acid. (This form of Vitamin B seems to be the most important single component.)
I am at 50mg/day to keep it at a level where the "flushing" is very occasional and very minor. My Karma tells me that, for seniors, flushing eventually tears us down.
Combined with one to two hours of napping, not letting my heart rate go over 95, and never pushing past the point of exhaustion--physically I have improved from a 3/10 to a 6 or 7/10 after about 6 weeks on the regimen. (Memory isn't great, but at least it isnt shutting down anymore!)
Again, thanks!
Evans
Thank you so much again for all the work you have put into exploring long covid. I am so grateful.
Thank you Gez an Dr. Wentzel! This was one of the most encouraging films! The biochemistry is quite complicated but i look extremely forward to the publication! I believe the good thing with LC is it will have positive impact on medicine and how we approach certain diseases. Very very thankful for what you do!
Thank you Tanja!
Thank you so much Gez! Your videos have been so helpful to me over these last, long 22 months. This video in particular was of great interest to me as I have hypermobile Ehlers Danlos, Sjogrens, Lupus and Fibromyalgia. All of these conditions were well under control, in remission until I got covid which caused a horrible autoimmune response that brought them all roaring back with a vengeance. In addition, I've now been diagnosed post covid with hyperadrenergic POTS and MCAS. So your question about the involvement of connective tissue really hit home as I've also seen numerous people in my long covid group now being dx'd with hEDS. I can't wait for Dr W's paper to be published. Thank you for helping to put all the puzzle pieces together for us!
So sorry to hear you’ve been suffering so much - like you say this really does start to put it together. Wishing you the best in your recovery.
@@RUNDMC1 Thank you ❤️
Those collagen genes seem to be heavily over represented in me/cfs too.
Hi Gez, thank you for doing these videos. Please don’t stop! Lol My tachycardia/pots seems to be improving slowly. Thanks I’m large part to you. Genuinely thought I had no joy in life ahead of me for months but slowly seem to be getting better. OTC antihistamines, Bvits, Vit C and Iron seem to be improving things… that and gradually undertaking more. Thank you so much.
Take it easy and try to build as much joy into your life as you can :)
How are you doing i have tachycardia and pots too
@@carmella88 the tachycardia which was confirmed as Pots has gone. Took 8 months.
@@comicbossone2411 this gives me so much hope. Did u do anything to make it go away or just on its own
@@comicbossone2411 i see in your comment now what you took .. what antihistamine did you take
Thanks again for your work. I wish the doctor would have used a microphone like yours. For me with English as a second language it was very difficult to understand him. :(
Really hard for me too. Echo is terrible.
His South African accent will not help those who expect received pronunciation.
@@stephaniewilson3955 it definitely adds a layer of complexity to an already unfamiliar situation!
This is brilliant Gez, so well produced, documented and lucidly explained. Soooo much easier to get a handle on than his pre - print! Dr Wentzel is amazing. I hope his wife forgives him for spending the last year in the lab/with hospital patients, trying to crack the dysfunctional metabolism of LC. 😀His unstoppable enthusiasm and contagious positivity will, I'm sure, deliver on finding effective treatment protocols for LC patients in the near future. NHS, please listen.
Thank you Carol, you’re right this is top class stuff!
Gez I am new to your channel and can't thank you enough
Total pleasure!
Interesting, thank you. This ties into a paper by Matsuyama suggesting that positive feedback between pai-1 and stat3 is responsible for many of the symptoms in acute covid. Pai-1 and hmgb1 act as DAMPs and activate tlr4 which triggers innate activation and cytokine release, and stat3 hyperactivation leads to fibrosis and lymphocytopenia. It feeds back on itself and perhaps becomes chronic. Quinolinic acid/kna, at least in animal models, stimulate pai-1.. and pai-1 is already raised in many metabolic conditions such as insulin resistance...and tlr4 activation stimulates the kynurenine pathway as a homeostatic adaptation in response to infection, especially lps mediated. Would be interesting to see if people noticed improvement with tlr4 inhibition. Hops has an anti-inflammatory effect via this pathway.
Chew or drink?
Thank you! This goes far to help me understand and will likely convince a few doctors that this is NOT "all in your head." !!!
Thanks for the great discussion - it gives us hope knowing this important work is being done in the trenches. And it's also great that people like yourself are wrestling with the bigger picture to see how it all fits together. I think the process of 'joining the dots' between micro and macro is the often overlooked aspect that will ultimately reap the most benefits for long haulers. Thanks again.
Apologies if this has already been asked. If - as Dr Wentzel said in your previous video - one can expect to recover in about 1 - 2 weeks on the treatment stack, assuming that the problem mainly concerns NAD and not myopathy - how long would one stay on the treatment thereafter? Thanks for another great video, Gez.
Yes am thinking the same thing Helen. Thanks for posting. Is an expensive stack to purchase. Am just about to start and interested in how long I should continue if my symptoms improve.
Adding another thank you for the videos Gez and all the hard work you are putting into collating this research. For the first time I feel hopeful.
Glad I dodged the tinnitus and erectile dysfunction symptoms 🤨 great work from the doctor again 😁👍 thanks fellas.
Haha. Thanks Richard!
Thanks for this interview. Mostly over my head but I'm going to look into the proposed protocol. Was there a clinical trial that cured long haulers or is this protocol still theoretical?
Also, I vote for a video on BC007 next!
Thanks Danielle - as far as I know there hasn’t been a published trial with this protocol. Leave the BC discussion with me!
Every longhauler from 2020 practically did this..I think I'd there was any significant recovery from it there would be "The Stack Pack" long covid recovery pack sold on Amazon by now
Thanks Gez, a very positive interview (albeit quite difficult to keep up with the terminology!) It all stacks up for sure. One this Dr. Wentzel said in passing was that he had found a mechanism to explain the tinnitus that many long-haulers suffer. Can you point me to where I can find this? Thanks! Keep up the great work and get better yourself.
FLCCC
Great informative video Gez! Thanks to Dr. Wentzel as well for his insights!
Thank you as always for all your hard work . I must admit this particular podcast was hard for me to take in whether that's my covid brain or just me - probably just me 🙄👩🏼🐾👍
Don't worry I was pushing through the brain fog to keep up too!
It’s properly hardcore - I only got my head round it on about the third time of watching it back during the edit!
@@gracemonk5873 I genuinely thought it was just me - Thank you 🙏
@@RUNDMC1 - Thank you Gez for helping me feel better 🙏I was having flash backs to my school days 🤓
I don't have much brain fog anymore and it was mostly Greek to me too
Fantastic!!!!! episode. I've wondered about this from the first time I heard Rob Phairs mitochondrial dysfunction. This puts a lot of things together
With so many of us experiencing constant and sometimes debilitating tinnitus, I was curious if this has been addressed in any of your interviews? I can press on the nerve bundle behind my ear and it almost goes away. It makes me want to dig into my skull there and pull out the nerve bundle, lol! Just kidding, I wouldn't do that. It is the one thing that is constant and I can't get rid of completely. Thank you for all you do, this channel has been so enlightening and helpful.
There is hope after 2 years my symptoms thanks God are improving specially since the last 6 months . I even tried to stay home for 2 weeks to see if I get a relapse and didn't happen unlike a year and half ago
Really? Now you 100% ?
I have had Long COVID since April 2021. Included a TIA event while driving the totaled my car. Have been extremely concerned about controlling blood clots, as well as CFS, loss of sense of smell, tinnitus and loss of stamina. Was very interested in this video and since I already taking most of the suggested regimen, I decided to take 20mg of nicotinic acid along with 200mg L-tryptophan daily at bedtime. I was surprised to see a noticeable improvement in only 2-3 days. After 2 weeks of this regimen, my stamina is greatly improved and I now do routine maintenance chores around the house including working on my car and wood working. I may get tired after several hours of work but recover over night. Before starting this regimen, a fourth of this much work would have taken me out for several days. Extremely happy with these results. Now wondering how long to continue this supplementation. If depletion of NAD+ was the cause, is continued supplementation required after NAD+ levels are restored? If the recycling of NAD+ has been affected, continued supplementation may be required. Any anecdotal information available here?
Pre med here, agree w all u r doing/infected same time/autoimmune/vac injured/long Lyme, etc.. go on De Mandell, free, sells nothing/likes serrateoase.. whatever I am on(natural), I go off it periodically and do 48 hr intermittent fasting.. green tea no good for histamines, mast cell activation, tu / best to all🙏🌷♥️🕊️
Your videos are excellent, Gez. So well researched and informative!
Thank you Cathy!
Probably the best video on the subject I've found, along with your mast cell interview. Nice one.
Thanks Tony!
@@RUNDMC1 Gez how are you doing now? Did you get any benefit from Dr Wentzel's protocol? I think I am starting to. I think the niacin helps as well as the reduction in exertion.
I must have listened to this 50 times. It’s totally changed my life. I’m feeling 97% better thanks to Niacin. Eternally grateful to Dr Wentzel et you Gez 🙏🏽
So glad it’s made a difference Victoria!
Victoria what symptoms did it help you with
@@nchoulagh the crushing fatigue and the walking waist deep in mud aching tiredness in my legs… I still have mottled skin at different times of the day but honestly this has made a big difference (plus I have MCAS and for that I’m on a H1 and H2 once a day). Still have brain fog though
@@victorianalin5885 how much Niacin are you taking?
@@aineotoole3686 i started off with 30mg p/d and slowly, slowly worked up to now 80mg 3 x p/d.. the Niacin I bought is 10mg tablets so i can easily dose as I want… Aiming for 100mg 3 x p/d.. recently been feeling the heavy legs again (but still no fatigue). Feel this higher dose is working on a deeper level and have good days and more challenging days where symptoms resurface.
RUNDMC, I have not seen your videos in months and I am subscribed. So happy to see you again.
Thanks Mari!
Another super informative video thank you so much Gez. I’m just wondering if you’re aware how long Dr Wentzel prescribes the stack for ? Thank you :)
Thanks for the great interview. A couple of thoughts; I believe apigenin has also been found to drive down CD38 and is more bioavailable than quercetin (I take both). Its not surprisingly that low NAD might be linked to more niacin flush as I believe the flush has to do with systemic inflammation. Finally, the more recent studies do not seem to support resveratrol as a sirt activator (see Dr. Brad Stanfield). I'm currently taking niacin and NR.
What is NR?
I’ve had CFS for 26 years and long covid for 2, I can barely take any niacin without intense flushing
@@lauraharding3101 nicotinamide riboside
What about taking B Complex for all the B Vitamins
@@doraprinsloo9468 anyone with MTHFR mutation cannot take folic acid. I take B minus and B12 and folate. About 50% of people have that genetic variation.
How do we find his papers? My doctors will not watch the video? This guy is spot on for my daughter. Dec 2020 long covid 19 years old 3 degree black belt. Suffering now.
Thank you so much for sharing this info. Having the flushing kind of niacin gave me relief for the first time in weeks after just a few doses. It felt like my skin was tingling with hot sauce fire for a minute but then was like the cloak of fatigue lifted and I had so much more mental clarity. I’m not feeling anywhere near 100% but felt like I went from feeling 10% to 50% with this one change alone. Thank you!
Great to hear it Thomas!
Another great and optimistic film. I’d better get back on the Niacin!
Indeed!
As someone who has experienced varying frequencies and intensities of cfs/me since having mono in 1968, the absolutely disabling exhaustion I have been experiencing with long-coved since initially having covid in October of 2020, is in a class by itself. I have just begun self-medication with Truniagen under the data-supported hypotheses that nad+ is depleted by covid-19, as well as in cfs/me, and chronic kidney disease, which I have had for 20 years, and autoimmune connective disease diagnose 25 years ago.. Pray this will improve nad+ production, and utilization, and Sirt 1 activation..
Hey I have similar medical issues. Did you find some relief and if so what helped ?
Gez, your efforts are priceless! Thank you so much for your videos.
I'm 12 months with LC now and i would like to know how do you feel after your "experiment in the Alps". Are you probing with more 'sport'?
Greetings from Spain ❤️
Feeling good post trip to the alps. Considering some more gentle activity!
Thank you very much for this video. Dr. Wentzel laid out a perfect puzzle of possibilities. The problem is, not even specialists would agree to test for these indicators. May I ask Dr. Wentzel if he investigated phytanic acid, x-linked "VLCFA" (very long chain fatty acids) as another indicator or even as a marker?
Thank you so much Gez! I’ve just discovered your videos (way too late in the game but nonetheless incredibly helpful) and I love how easily you explain everything and interact with these amazing doctors. With approval of my many doctors, I’m going to start this protocol. I’m sorry if this question has already been answered, but is there less effectiveness to taking “flush-free niacin” with inositol hexaniacinate rather than just niacin? I know that Dr. Wentzel explained the flush is important for the NAD enzyme, so I’m wondering if I should just take that? Thank you so much! I greatly appreciate what you do! 🙏🏼
Hi Jocelyn, thanks for the comment! The flushing variety does seem to be more effective so if you can tolerate it it’s worth having. If you don’t tolerate it then non-flush will still be OK :)
Thank you for making these videos!! Very interesting information today.
Thanks Anna!
Excellent video! Does anyone know if Wentzel is in touch with Ron Davis? Davis has been studying this exact pathway, and is currently trialling off label use of FDA approved medications to get at it.
Yes! I was wondering the exact same thing. Would be great if these scientific minds could work together!
I did not know about him until you mentioned him here. I looked him up and quite a story with his son, but could be a blessing for all of us as he seems like a top level researcher. I sure hope he solves for all of us.
@Gez - Ron or his wife Janet would be great interview subjects :)
Thanks, Gez. A couple of questions:
1. Why (specifically) is it important to not go above that maximum heart rate? Is it to prevent the post-exertional malaise / symptom triggers of an over inflammatory response and/or is it dangerous onto itself, as one might consider with a peri or myocarditis diagnosis? (I still feel instinctively very cautious about increasing my heart rate, and mostly just do daily walks or gentle stretching or very light dancing).
2. Do you think we're likely going to just have to accept permanent lifestyle changes, and not going back to our (for many of us) prior athletic norms?
3. It seems true, anecdotally, that very few of us are experiencing a full 100% return to baseline, at least at this 2 years and under point. Did you understand this doctor to be saying that what we're looking at is management of auto-immune conditions and/or optimizing recovery to as fulsome a point as we can? (Sorry, couldn't quite get through all the dense biological / chemistry mapping!) I mean, was he saying, many are getting to 60% recovery and some all the way to 97% but almost no one to 100%. Did I get that right?
4. I look forward to you distilling your summaries of knowledge into lay person treatment recommendations, especially any updates or ideas you have about either this root-cause support and/or key tips for treatment for any particular symptom clusters.
5. I also remain truly curious and hopeful for your thoughts (if any) or handling future Covid reinfections and/or endless boosters, as it feels like the world is opening up again and it seems almost certain many or most of us will be exposed again at some point or another. I'd love to hear what you might do (if anything) in that instance, for yourself, to give us food for thought, too.
As always, thank you very much.
Gez has a lot of videos here on the practical side of dealing with LC. They are all worth checking out. Most rightly have a theme of not overdoing it, but watch "The Great Experiment: Can Activity Play a Role in Long Covid Recovery?" th-cam.com/video/UCJhYAQ6aGk/w-d-xo.html
Hi Nicola - gosh, a lot here to address!
1) The HR limit is to manage the risk of PEM. Intensity of activity seems to be the major driver of it so by limiting HR we minimise the risks
2) Honestly at this point I don’t know. I think a great many of us won’t get back to where we were before covid, but if we can still live a full and rewarding life that’s what we should focus on, difficult as it may be!
3) Dr W is saying that he has seen long haulers make full recoveries. From my part I don’t know that many of them - most people I know who have recovered are getting back to 90% perhaps. I have known a couple who thought they’d made 100% then relapsed.
4) It’s coming! Announcement in the next couple of weeks :)
5) This is a f***ing minefield. Massive catch-22 re boosters. I think all you can do if you get reinfected is just to do everything right we didn’t do the first time! ie massive rest, get on the stack if not already, take anti histamines, aspirin and if you can get other anti-coags then those too.
Hope you’re doing well!
Ive been having tension headaches , migranes , eye pain and chest pain for 6 months after contacting covid. All doctors are gas lighting me telling me its anxiety. This channel is the only thing helping me
So sorry to hear this Andy
Thank you Gez for all you’re doing regarding long covid and all those suffering (a year now for me)! It sometimes feels like there’s little chance or hope of getting over this. However seeing these videos and pathways to what will hopefully be a full recovery is brilliant. Can I ask if regular drops in blood sugar/ hypoglycaemia is also linked to long covid?
Yes I’ve heard people report this but it’s not super common
@@RUNDMC1 Ah ok. I have that going on as well but never high blood sugar. Kind of hoping it’s linked rather than a separate issue. Thanks for your reply.
Many many thanks for this.
Really great knowledge, that we don't get through public health.
Thanks for being a bit of an angel of necessary knowledge.
Greetings from Berlin!
Thank you Miska!
Thank you for these videos. However, the niacin/C/D/zinc/selenium/quercetin helped at first, but after about 5 days I started getting the same old symptoms back again- headache, stiff neck, burning eyes, brain fog, GI disturbance. Not really sure what to think. When I take benadryl my smell comes back briefly. When I exercise too hard, within a day or two all these symptoms come back hard. Tried many supplements, probiotics, etc... Still looking for a cure for Long COVID. I feel like you are getting closer but what is missing from these interviews is the origin of the problem. For example, WHY does covid cause niacin depletion? Or WHY do covid antigens cause polarized long-lived inflammatory monocytes? Something is missing to unite all of these theories together, the original cause of the damage from COVID. I am still not seeing that, at least not consistently for all long haul patients. It seems that some people are helped by some treatments, but there are definitely plenty of us still not getting better.
It sounds like Mestinon should help with POTS according to this theory - interestingly Mestinon has been found to be helpful for many people with POTS.
Mestinon is a cholinesterase inhibitor, it increases the amount of acetylcholine at the synaptic junction.
American physicians I've been to ignore the links due to long covid. I'm beyond feeling defeated from it all
Don’t lose hope LV!
@@RUNDMC1 thank you, I've been longing to have 48 hours of feeling good ❤
I’ve worked up slowly to 2 x 50mg Niacin p/day with the rest of the stack and honestly I feel like it’s helping, less exhausted, can do more physical work without getting totally wiped out and less circulation problems in my legs which was the worst 🙏🏽 Have you felt a difference Gez and what’s the optimal daily dose theoretically? Has Dr Wentzel’s preprint been published? Why isn’t there more media coverage about his work???
I described my energy crash more akin to a feeling of what I think dying would feel like or finally running out of gas and the car stops.
Yep!!
I wonder if this explains the massive clotting in my groin that took 3 operations to clear something like 15 months after first getting long covid.
That sounds awful - so sorry to hear that Stephanie
I started this protocol and instantly felt better. Thank you so much Gez!
Another good one, thanks for putting this together.
Thanks Gary!
Someone mentioned there's a transcript for this? If so, please let me know and post it (or a link) in the description. Thanks so much!
Do we know how long this will last . Will we get better I have come around alot but am still always tired if I train I end up in bed for days 16 months never once felt me old self
I had long covid after early infection march 2020. Am better now, i was very careful when introducing exercise in my case gardening (my job) dog walking. I would work 2 hrs then rest all afternoon at first. Slowly built it up over 2021. I didnt take anything apart from ibruferon occadionally and vit D which i think helps greatly. Hope you get better soon.
Well explained about the separate niches rather than the holistic entity
Hi Gez,
Thanks so much for your content as usual! I feel very grateful that I am at the point now where I feel largely back to normal after 16 months, I can exercise again without any serious repercussions and can live a pretty normal life. However, I still generally feel a bit foggy and lack energy and just don't feel quite 100%. I wondered if you had any insights into your experience with aphresis - I've been offered a slot and am debating whether it would benefit me and my symptoms. Would love to hear any insights from you or anyone else with experience!
Thank you for all the videos you’ve posted. My very sporty daughter aged 15 has developed Orthostatic Intolerance since contracting Covid. She also has Covid Toes, or Erythromalagia. fatigue, constant headache (band like), brainfog extreme, eye focus problems too when headache is bad.
Looking at the diagram is seems to all point to: kynurenic acid and it’s impact on the receptors.
How best to fix? Thanks for sharing the protocol.
She’s on several supplements, but not Niacin!, histamines, anti coagulation, lots of water, lots of rest. Five months in now.
Try the niacin! Start off on a low dose (20mg) and work up
Love this - but wondering why thiamine is left out? It's an important coenzyme in the Krebs cycle. Adding it to my stack made me improve hugely on so many things that were still persistent
How much Thiamine do you take daily?
@@aineotoole3686 Still exploring what would be the optimal dose for me, but right now I'm taking 150 mg benfotiamine and 100 mg thiamine hcl.
Huge info. Why does LC happen to some people and not others though? Almost everybody I know doesn't believe it can happen for years out and didn't experience it when they got covid.
It's likely due to different susceptibilities, both genetic and lifestyle. My theory is people with highly sensitive immune systems but weaker repair systems, young men and child-bearing age women, have their bodies "freak out" during infection and cause a bunch of damage, and the body is unable to repair itself properly without a serious boost. Children's bodies can repair easily, and older people as well as less healthy people actually get less damage from their own body because its weaker firepower means less collateral damage. I had an incredibly strong immune system as a young man, hadn't had more than a head cold in five years, and long covid has absolutely wiped me. Meanwhile my obese parents seem to be completely fine.
Could someone simplify this protocol into a daily supplement list? This is too advanced for me to understand - good job though
agree
Great video Gez, really hope we’re getting closer to a brighter future. 🙏
Me too!
Fascinating stuff Gez. Have taken a bit of a break from the Niacin but maybe its time to revisit my old flushing friend...
I would do Edward!
Great video once again Gez! I have a question for you about the neurological symptoms that lie under the umbrella term brain fog. Does the data that we have today indicate that:
- It is temporary
- That permanent damage have been caused
- (Or worst of all) that our cognitive abilities will continue to deteriorate over time?
I would put money on the first of those camps, but we don’t have hard data on this unfortunately
@@RUNDMC1 I hope your right!
I agree with Gez. Neuroscience has shown the brain to be neuroplastic - the ability of neural networks in the brain to change through growth and reorganisation. I believe we absolutely can “retrain” our neurological pathways and improve brain function with corrective actions. Dr Andrew Huberman (neurobiologist) has some great content on this. I also think Dr David Siclair’s research is also important for cellular regeneration etc. The scientific community are making enormous strides in putting together many of the puzzle pieces. What we need now is one body/organisation/NPO to bring it all together (like Gez is doing) for all of us to benefit from.
Great work, as usual, Gez! BTW, did you suffer any symptoms after your ski trip?
No - ski trip was extremely positive!
@@RUNDMC1 that’s great to hear!
My Omicron long haul is happily just paralyzed both my thumbs, the left one is worse and is swollen. It comes and goes, fasting helps but I call it funky thumbs and I am happy is it not funky anything else, but I like my thumbs and I'm confident some day they will return to a less paralyzed state. Other long hauls were far more unplesant and the recurring feeling of being near death was far too familiar to them all.
Gez have you got an update for Dr Wentzels new paper, the glimpses & methodology were very interesting, I keep looking to see if it’s published. I’m almost 12 months on vacc damaged with AZ, thanks
Haven’t got a date yet but it’ll be soon!
I had considered NADH, I was on the right path.... Thanks Dr!
How can we find his paper? My doctors apparently don’t like videos. This doctor is spot on. My daughter has pots/long covid since dec 2020. Keep the intel rolling. Awesome job.
Doing some great work Gez, thanks for that!
I have some questions about the dosage of some supplements. Some speaks for itself, but others are not that clear for me (and my brainfog)
The quercetine is a lot less than the 'first stack' where 3x 500mg was prescribed. Is this due to the fact that now is spoken about quercetine anhydrous? I am now using di-hydrate
The methylcobalamin I find the most is about 1000mcg, that's way too much in this case?
Where does AAC at selenium and zinc stands for? The dosages of selenium I find the most in supplements are about 100mcg, so a dosage will be 10-30 pills? I think I am overlooking some details..
Highly informative and thought provoking discussion. Quality listening. Learn and teach. Thank you. 🔜👊🇺🇲