Ovulation with PCOS: Is Clomid or Letrozole better? What Is Ovulation Induction?
ฝัง
- เผยแพร่เมื่อ 23 พ.ค. 2024
- Double board certified OBGYN and REI, Dr. Natalie Crawford, discusses ovulation induction and PCOS. It is completely normal to need help trying to ovulate when you have PCOS and nothing to be ashamed of. PCOS is one of the top causes of infertility so it's important to know which method of ovulation induction is more likely to result in pregnancy.
Questions Answered:
What is PCOS?
What are PCOS misconceptions?
What happens when you ovulate?
What is FSH?
What happens to your eggs every month?
What role does the brain play?
What happens if you have PCOS?
What are PCOS symptoms?
How does weight play a role?
What is metformin?
What is Clomid?
How does it work?
How does letrozole work?
What do the studies say?
How does AMH play a role?
What is a normal period?
Do you need IVF with PCOS?
www.nejm.org/doi/pdf/10.1056/...
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Fertility doctor, Natalie Crawford, MD is a double board certified OBGYN and REI, and co-founder of Fora Fertility, a boutique fertility practice in Austin, Texas.
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Sharing fertility facts to educate women about trying to conceive, getting pregnant, ovulation, fertility treatments, IUI, IVF, becoming a doctor, life as a woman in medicine, and more.
After watching your videos, I would like to say that I am truly blessed. I have been struggling with PCOS for years and it wasn’t until I started TTC was when I found out I had PCOS. We tried for 6months all unsuccessful, doctor put me on 50mg of clomid and I got pregnant my first round. We are truly best! Currently trying for baby number 2.
We congratulate you very much. We hope your children are healthy and successful😍
As a doula, I’m obsessed with your videos! You explain women’s health so well. I’d love if you did more videos misconceptions with pregnancy and outdated information to watch out for.
All the love from PDX❤️
Such great information and I'm glad that study was done! I started with clomid and didn't respond but responded alright to letrozole (with RE monitoring). Ultimately, I needed IVF but at least letrozole got me ovulating where clomid just left me frustrated.
Thank you for sharing your experience! It's so helpful to hear from other women who have been through similar journeys. I'm glad to hear that letrozole was able to help you ovulate, and that you were ultimately able to achieve your goal of becoming pregnant with IVF. You're an inspiration!
Pcos girlie here! I’m a little confused. I have a period every month but I don’t ovulate. My Lh levels are super low. Ive been on metformin for about 8 months now and still not ovulating. Now will start leterozole soon. Is that common to have a period and no ovulation?
Hi Natalie! Would you be able to do a video on the topic of post-pill amenorrhea / PCOS / irregular periods for younger women not looking to conceive but just regulate their cycle? Would love to hear your thoughts on this and any ovulation induction methods for this (e.g. Metformin). Thank you always for the amazing and informative videos!
same can i take letrozole
Dr. Crawford, in the video you mentioned that with PCOS, it is common for multiple eggs to develop at once. You also mentioned that Clomid can cause a thinning of the uterine lining. Is Letrozole (lrel) less likely to cause a thinning of the uterine lining than Clomid?
What's the best foods to eat to improve ovulation?
I had a miscarriage at 9 weeks and a D&C 4 years ago. Ever since then we haven’t been able to conceive. After watching your videos I had commented on one of them and you suggested to go get an evaluation for scar tissue which I have scheduled now. My periods are normal I do ovulate which I track every month.
My question is what do I ask my ob what tests do I need to do? I can’t afford any doctor’s apt. So this is my only apt at the moment.
is it safe to take Ozempic for PCOS while trying to conceive?
So we've been trying for over three years, finally this past winter we started at a clinic, and was diagnosed with pcos this spring - next period cycle, we're starting letrozole, but you know, that could happen on... whenever my uterus gives up on WAITING for a damn egg that isn't coming lol
I'm so sorry to hear that you and your husband are having trouble getting pregnant. I know how frustrating it can be, especially after trying for a long time. A PCOS diagnosis can be challenging, but I'm glad to hear that you're finally seeking professional help
What are the options for someome with high AMH?
Women with high AMH typically have active ovaries with a large number of eggs. This can be an advantage for fertility, as it means they are more likely to ovulate. However, women with high AMH are also at increased risk for ovarian hyperstimulation syndrome (OHSS) during fertility treatment."
I have an AMH of 9.1 & I am 35yo. I do not have PCOS. We have been trying for 19 months. Within that time frame we have had, 13 months on induction medication (both clomid & letrezole) & 3 failed iui’s. I only grew 2 dominant follicles on 150mg of clomid, but it thinned my lining. Is this common without having PCOS? Would using injections be a waste of time? Thanks!
I'm so sorry to hear you've been struggling to conceive for 19 months. That must be incredibly frustrating, especially after trying medication and IUI cycles.
Here are some thoughts, but it's important to remember I can't give medical advice:
An AMH of 9.1 at 35 is generally considered a good reserve. It suggests you have a good number of eggs. However, AMH doesn't tell the whole story about egg quality.
Thinning of the uterine lining can happen with Clomid. It's not uncommon even without PCOS. Letrozole might be a better option for some women in this case.
Injections (follicle-stimulating hormone or FSH) can be a good next step. They offer more precise control over ovulation compared to Clomid or Letrozole.
Definitely discuss your situation with a fertility specialist. They can review your medical history, perform tests, and recommend the most appropriate course of treatment for you.
Hi Natalie. Can you please explain ovulatory PCOS but no getting pregnant
The main obstacle with PCOS is ovulating, so if you know for a fact that you ovulated that cycle then it isn't anything to do with PCOS. If you released an egg and there was sperm to fertilize it, either the sperm never got to the egg; if it did, the embryo didn't implant; or maybe the sperm isn't compatible with the woman's immune system. Keep in mind as well that a healthy, fertile couple in their mid-twenties still only has a 20% chance of conception per cycle, so even if you do ovulate it isn't guaranteed.
I think the hormone imbalances associated with PCOS, particularly high testosterone, can impact egg quality, which can make conceiving more challenging even if you ovulate.
We've been trying for 4 years with a diagnosis of PCOS and started clomid rounds 2 years ago and I got pregnant our first cycle with it but unfortunately miscarried at 8 weeks and had to get a D&C. I had a chemical pregnancy 2 months after the miscarriage and had 2 more cycles on clomid with no success. I started letrozole at the beginning of this year with still no luck...what should I do next? Should I suggest testing to be done by my OB or should I go see a fertility specialist and talk about ivf?