Thank you for your video that was very useful, if it binds irreversibly but then those cells are then replaced that means their effects won’t last forever right? So why is it only usually given short term as in 4 weeks and not lifelong? Won’t those symptoms just come back if it’s stopped after 4 weeks or do their effects reduce the acid production forever?
It depends on the underlying reason for the need for PPIs. Often a period of protection allows the gut to recover sufficiently to mean that stopping them is okay. But some people have conditions or take medications which require long term use.
Long-term it can impact nutrients which prefer an acidic environment for absorption - that includes B12, calcium, magnesium and iron. We're talking long-term use though - well over a year - and if that's the case your prescribing doctor may want to keep an eye on it. People who have diets already low in those nutrients (e.g. vegans for B12 and iron) are arguably more at risk. Great question.
Yes, your stomach will be creating more and more such cells, changing its lining and that’s why you get horrible rebound. Long term PPI will scrw your kidneys, liver and… your stomach! Awesome drugs! See a naturopath to heal, or ask your AI. Fck these pillpushers.
Thanks for that explanation. Have recently started on omeprazole before my midday and evening meals as I cough after eating, but no burning sensation in my throat, so didn't think it was reflux. Seems to be working but now I know why
If PPI stops my stomach from producing acid then how am I able to digest food? And for how long does it prevent this? Could have continued on another 5 minutes
Good question. 1. A ppi won't stop all your acid 2. Cells turn over really fast so they'll start getting replaced immediately and producing acid again 3. You can digest in lots of ways, not just acid. Hope that makes sense
Unfortunately no. Long term PPI use has been linked to vitamin deficiencies (B12 and magnesium), dementia, muscle and bone weakness, as well as increased risk of infections. However some doctors may still prescribe long term if the benefits outweigh the risks
@@myopinions1 tums is used for instant relief of acute cases of reflux. a patient with GERD won't get much relief from sodium bicarbonate, maybe a minute or two of no reflux. severe chronic reflux is not so simple to treat
It is most humbly requested to describe and present the most reliable sources of information, data, statistics on diseases and latest treatment with in-depth research on updated medical science proven in the public interest... - On request: World Conscious medical community and patient welfare society.
That was really a narrow and unscientific "explanation" against an alkalising diet. While the burger and french fries are burning under the stomach acid next to him.... It's just not credible to listen to as a health "expert". Wrong messages.
What a weird piece of criticism. That’s exactly what they were going for; you can tell by the script and video effects that they’re going for more of a casual and entertaining (as entertaining as you can make a video about the chemical processes of stomach acid) vibe. If you want a “scientific” explanation, I’m sure there’s something else out there for you.
Scientifically, he’s right about the alkaline diet. I fell for all the mumbo jumbo for years. Thankfully I was challenged by others and got better at critical thinking and found the truth. I encourage others to find it. It’s been years since coming out of that rabbit hole so don’t have any link to videos or articles to share here. Beware of confirmation bias. The tendency to only look for evidence that confirms what you want to be true.
Did u actually ever have an erosive gastritis? Leave the books alone, dear Doc. Those advices are not for serious stuff. Just for minor things that heal fast. Long term use of PPI's actually leads to way more production of acid in the stomach... so NO. Do not take PPI's for periods longer than 14 days. The best way to actually start curing the problem is by diet and aloe vera juice (with no sugars, no aditives). That can keep your acidity low. Things like steamed greens like brocoli, steamed chicken, eggs, low fat milk, low fat fish, steamed carrots, avocados, baked apples, and so on. And when you get a flareup eat oats to get your stomach to calm down. Be patient And loose the stress.
So informative!🙂
Very helpful...Can you please do more of these videos (pharmacology). Many thanks.
I'll do my best
Excellent . Thanks Dan. Judy
Thanks so much. Great video. I'm tapering off omeprazole right now but I was always wondering how it works.
Glad it was helpful ☺️
Thanks for great explanation. I have watched almost 6 videos before this and I just didn't get it. I am lucky I found your video. problem is solved
My pleasure!
Excellent. Thanks. Judyxx
Thank you for your video that was very useful, if it binds irreversibly but then those cells are then replaced that means their effects won’t last forever right? So why is it only usually given short term as in 4 weeks and not lifelong? Won’t those symptoms just come back if it’s stopped after 4 weeks or do their effects reduce the acid production forever?
It depends on the underlying reason for the need for PPIs. Often a period of protection allows the gut to recover sufficiently to mean that stopping them is okay. But some people have conditions or take medications which require long term use.
I thought it has the potential to interfere with certain vitamin & mineral absorption? Is that not the case?
Long-term it can impact nutrients which prefer an acidic environment for absorption - that includes B12, calcium, magnesium and iron. We're talking long-term use though - well over a year - and if that's the case your prescribing doctor may want to keep an eye on it. People who have diets already low in those nutrients (e.g. vegans for B12 and iron) are arguably more at risk. Great question.
If they irreversibly binds to the proton pump, does it means that the proton pump they are bound to will be forever inactive?
Good question. Those cells - yes. But the cells of your gut lining are replaced at a very quick rate, so there'll be new cells to bind to soon enough.
@@TheStealthDoctor Okay, understood. Thank you for your response! You could do a next video on statins, you explain so well.
Thank you! Re statins: I've already done it Crystal, check out the other vids on the channel 😁
Yes, your stomach will be creating more and more such cells, changing its lining and that’s why you get horrible rebound. Long term PPI will scrw your kidneys, liver and… your stomach! Awesome drugs! See a naturopath to heal, or ask your AI. Fck these pillpushers.
Thanks for that explanation. Have recently started on omeprazole before my midday and evening meals as I cough after eating, but no burning sensation in my throat, so didn't think it was reflux. Seems to be working but now I know why
Sounds like silent reflux. Glad you're feeling better!
I feel attacked (and informed).
That's you stomach acid attacking you.
If PPI stops my stomach from producing acid then how am I able to digest food? And for how long does it prevent this? Could have continued on another 5 minutes
Good question.
1. A ppi won't stop all your acid
2. Cells turn over really fast so they'll start getting replaced immediately and producing acid again
3. You can digest in lots of ways, not just acid.
Hope that makes sense
Thanks Brother, But are these PPIS safe, can we take these lifelong.. ? please reply
Unfortunately no. Long term PPI use has been linked to vitamin deficiencies (B12 and magnesium), dementia, muscle and bone weakness, as well as increased risk of infections. However some doctors may still prescribe long term if the benefits outweigh the risks
@@shea5581 Thanks a lot... is there any way to quit ppi usage, and overcome acid reflux
@@gurpreetsingh878
Try researching iQoro device.
Thanks alot
Itraconozole?
Can i take Omeprazole twice a day before meals?
20mg morning and 20mg evening is okay but dont take more than 40mg a day.
Face it the need for PPI's comes from the food we eat.
You're a "doctor" and can't figure out that alkaline foods and the medications work the same way?
Correct. I've even looked at the evidence and everything 🤷
@@TheStealthDoctor so what does tums do? And what about sodium bicarb in the ICU? Why is that needed?
@@myopinions1 tums is used for instant relief of acute cases of reflux. a patient with GERD won't get much relief from sodium bicarbonate, maybe a minute or two of no reflux. severe chronic reflux is not so simple to treat
There are plenty of side effects...SIBO is a major one!
It is most humbly requested to describe and present the most reliable sources of information, data, statistics on diseases and latest treatment with in-depth research on updated medical science proven in the public interest...
- On request:
World Conscious medical community and patient welfare society.
That was really a narrow and unscientific "explanation" against an alkalising diet. While the burger and french fries are burning under the stomach acid next to him.... It's just not credible to listen to as a health "expert". Wrong messages.
What a weird piece of criticism. That’s exactly what they were going for; you can tell by the script and video effects that they’re going for more of a casual and entertaining (as entertaining as you can make a video about the chemical processes of stomach acid) vibe.
If you want a “scientific” explanation, I’m sure there’s something else out there for you.
Well stop complaining and go and upload you're own short video to breakdown the use PPI s 😢😮
@@seanpavani8251 Fair enough.
I think it's everyone's right to screw up his or jer own health. 🤷♀️
Scientifically, he’s right about the alkaline diet. I fell for all the mumbo jumbo for years. Thankfully I was challenged by others and got better at critical thinking and found the truth. I encourage others to find it. It’s been years since coming out of that rabbit hole so don’t have any link to videos or articles to share here. Beware of confirmation bias. The tendency to only look for evidence that confirms what you want to be true.
Did u actually ever have an erosive gastritis? Leave the books alone, dear Doc. Those advices are not for serious stuff. Just for minor things that heal fast.
Long term use of PPI's actually leads to way more production of acid in the stomach... so NO. Do not take PPI's for periods longer than 14 days.
The best way to actually start curing the problem is by diet and aloe vera juice (with no sugars, no aditives). That can keep your acidity low. Things like steamed greens like brocoli, steamed chicken, eggs, low fat milk, low fat fish, steamed carrots, avocados, baked apples, and so on. And when you get a flareup eat oats to get your stomach to calm down.
Be patient And loose the stress.