The Risks of Proton Pump Inhibitors: How acid reflux medication can affect you in the long term

PPIs are powerful antacid drugs used in the treatment of Gastro-oesophageal reflux, providing relief from symptoms such as Regurgitation, Dyspepsia and heartburn. However, as one of the most prescribed drugs in the western world, with millions of people taking them, more studies are finding potential side effects from PPI’s. When the acidic levels in the stomach are reduced it can risk the decrease of diversity in the gut microbiome, leading to diseases such as minimally understood SIBO, with side effects such as digestive discomfort and bloating. In this video Mr Nicholas Boyle explains the potential ramifications of long term PPI use and why people should consider them.
0:00 Introduction
0:55 Who takes PPI's and how do they work?
3:45 How effective are PPI's?
4:44 Long term effects of PPI's
6:35 How conclusive are the current studies linking PPI use to various health risks?
9:42 The types of studies conduction into the risks of PPI's
11:37 What effects do PPI's have on the gut microbiome
14:24 SIBO and treating patients who don't respond to PPI's
Find out more at: refluxuk.com/

[@user-ms5ex9oy2r]

Thank you and God bless you for removing my persistent bad breth from stomach when taking & Gerd/Acid reflux symptoms completely when I came across Dr.Ohanon🥰

[@SpicySpaniel]

I had an oespohageal stricture (had it >10 years), no symptoms except the obvious swallowing issues. It was dilated last July and since the procedure, I have suffered with constant chest and sinus issues. I have no other symptoms, no heartburn, no regurgitation, no soreness , occasionally wind after eating. I am a dietitian and implemented all the lifestyle adjustments which made some difference but I used to run competitively and cannot run due to the constant respiratory symptoms. I think I have LPR, my gastroenterologist says LPR is over diagnosed and that I have normal reflux and need PPIs long term. The PPIs helped initially which I think was the oesophagitis healing effect but I still have symptoms. I am considering reflux surgery and I wish I had not agreed to the dilatation of the stricture.

[@countvonaltibar236]

PPIs definitely have a place but in my case the daily dosage I'd been taking for the last few years just weren't working anymore. I opted for surgery which to be honest I wish I had looked into a whole lot earlier. Now that I'm PPI free I feel a whole lot better and the surgery appears to have fully cured the reflux.

[@rubenaceves]

What was your surgery for?

[@countvonaltibar236]

@@rubenaceves Hiatal hernia repair + LINX

[@nwz6084]

Is the inhibition temporary from PPIs? I heard they are irreversible, and that scares me. Specially cognitive-related. Please let me know. can't find info anywhere.

[@Refluxuk]

Hi there - while there are still not many good quality studies around this, it seems as though many of the side-effects are
reversible on the whole. Hopefully we get some better data in the future to know with more certainty!