SOS Response and DNA Repair

The SOS response is a global response to DNA damage in which the cell cycle is arrested and DNA repair and mutagenesis are induced. The system involves the RecA protein.The RecA protein, stimulated by single-stranded DNA, is involved in the inactivation of the LexA thereby inducing the response. It is an error-prone repair system that is attributed to mutagenesis.
SOS genes include lexA, recA, uvrA, uvrB, and uvrD.
Source : en.wikipedia.org/wiki/SOS_res...

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[@hussainbiology]

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[@asraaal_dolaemy6138]

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[@hussainbiology]

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[@brtseif]

Lifesaver. Final tomorrow, this explains the process perfectly.

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Thank you!

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[@hussainbiology]

Glad it was helpful!

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What an amazing explanation sir
Keep uploading more videos !

[@hussainbiology]

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[@hussainbiology]

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This is amazing!!! 👏Thnks sir for such helpful videos..

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[@kaurviyadav6016]

Bhai sos response ki aisi video koi or na hai u tube pr...... Itna accha to pathfinder ki life science ki books mai bhi na diya.... Thanks bro keep it up👍✌

[@hussainbiology]

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[@hussainbiology]

kafi acha laghta hai jb koi aise appreciate krta hai..♥️

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[@swatisangwan4925]

Hussain Biology
Sir pls make a video lacture on expression of lac operon in merozygotes. all that constitutive and inducible phentotype.
Please, I will be so thankful to you.

[@rider-hb2op]

Daigramatic representation is superb that makes topic understand very quickly .. Osm

[@hussainbiology]

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Awesome video! Thank you!

[@hussainbiology]

Glad you liked it!

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[@hellohari85]

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[@hussainbiology]

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Fantastic teaching style. Thanks.

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Thank you sir ✨

[@hussainbiology]

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It really helped me

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Most welcome

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Thank you sir.

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You are welcome

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Shukriya Bhrata shri

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Much more concise than Shomu's Biology. I like that you get right into it as opposed to taking forever to introduce a new topic.

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Thanks Carl for appreciation....
I know this world has no time so , i always introduce topic as quickly as possible so that we learn what we have to....
Almost all my videos are around 5-6 mins.
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really helpful thanks

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Wonderful

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[@virendrapatel550]

nice. I have a question. Can you tell me how the cell regulates the preparation of uvrC and uvrD proteins and uvrA protein as they all come under the same promoter?

[@hussainbiology]

I have not read any specific regulation for uvrC ,D, and A proteins but i can say the majority of gene expression is controlled via DNA methylation and for these genes to be regulated it must be the CpG islands present on the genes that on/off the expression of any gene by Methylation of CpG islands.

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sir can u explain the new concept of primpol mechansism in dsb repair, it would be of great help

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[@hussainbiology]

Most welcome

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Super sir

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Great video. It really helped me alot. I request you to upload a video on DNA repair photoreversal please.

[@hussainbiology]

Thanks Shruti for appreciation...
And the Photoreactivation video is here:
th-cam.com/video/CwuXOmtl_zI/w-d-xo.html

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✌️

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can you please make a video on homologous recombination

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[@hussainbiology]

Surely.... thanks

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thank you for helping but next time please slow down when you are speaking wish you the best

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Nice video sir...

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Thanks Neha..... Glad to know that it helps.....

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Good and easy explanation👏👏👏

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[@juhisjunction274]

@@hussainbiology l used some of ur points in my lecture....thanks

[@ahmedshadulla7463]

It is uvr ABC Excinuclease.....operates the NER mechanism...

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Mashallah bhai bht acche

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EXCELLENTTTTTT

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hi sir can you please make a video on recombinational dna repair ??

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vry nice

[@hussainbiology]

Thanks Kashfa for appreciation...

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Can you please refer a book for this particular topic ?

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nice explain

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Very nice explanation, but pls go little slow, and sound is not so clear.

[@hussainbiology]

thanks for appreciation..... and i will definitely be slow in future videos

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Live 100. Not much, but the most n absolute explanation than shomu

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Thanks buddy for appreciation....

[@ramchandrasuthar2848]

Very nice analysis bhai ji

[@hussainbiology]

thanks bro

[@sravaninaraboina1216]

nuvvu

[@varshajetty1131]

Is it "Translesion " or "translation" DNA synthesis?

[@hussainbiology]

at 2:54 It is Translesion synthesis
The Translesion synthesis is a DNA damage tolerance process that allows the DNA replication machinery to replicate past DNA lesions such as thymine dimers or AP sites.It involves switching out regular DNA polymerases for specialized translesion polymerases (i.e. DNA polymerase IV or V, from the Y Polymerase family), often with larger active sites that can facilitate the insertion of bases opposite damaged nucleotides.

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[@renutailors4634]

Sir kya ye topic jo aap upload krte ho csir net ke liye h

[@hussainbiology]

G Poonam , all are for CSIR NET

[@nazishamin2548]

It will be nice to hear from you sir if you are from kashmir .

[@hussainbiology]

Yes Nazish , i am from Kashmir.. Greetings....😊

[@nazishamin2548]

Yes i am also from kashmir , the accent of your speaking made me recognise that you are a kashmiri too 😊.

[@nazishamin2548]

Nothing like that its my exam tomorrow and i am from srinagar brother.

[@hussainbiology]

@@nazishamin2548 All the best dear...

[@arivinmech4391]

What is sos genes

[@hussainbiology]

Any genes which help at the time of urgency

[@sinthy8447]

A bit slowly... Would be better! Thanks anyway!!!

[@poupouill21]

That's not an operon it is a regulon since it's not on the same gene

[@hussainbiology]

It is a type of Regulon , which falls under the group of operons........ i hope this makes sense

[@hussainbiology]

It is a type of Regulon , which falls under the group of operons........ i hope this makes sense

[@RehanKhanNISER]

thora shi se bolta ye nakli foreign accent boht ganda lgta hai...by the way video was nice and helpfull
i have exam in an hour.

[@hussainbiology]

Apologies........Will stick towards my real accent.

[@RehanKhanNISER]

@@mominayasmin6941 I don't even remember I commented this 😂😂

[@anushkasupakar3305]

So how does it make SOS repair a direct reversal repair mechanism? Since it is the last resort for the cell to repair extensive damages.

[@hussainbiology]

this happens to occur in bacteria as a global response mechanism.

[@anushkasupakar3305]

@@hussainbiology Okay so all the direct reversal mechanism occur only in prokaryotes right?

[@hussainbiology]

@@anushkasupakar3305 Na na....It occurs in Mammmals too.
Like Photolyases have vast diversity found within bacteria , fungi, plants and in animals too.
Furthermore direct reversals in mammals by MGMT protein
✓ AlKb mediated direct reversal in E.Coli.

[@anushkasupakar3305]

@@hussainbiology thank you for the clarification! Thanks a lot. Take care!

[@hussainbiology]

@@anushkasupakar3305 you are welcome...Keep sharing and supporting

[@arpankundu4982]

Lecture is very precious but pronunciation is not very clear...should not imitate foreign style ...otherwise very good

[@hussainbiology]

Thanks buddy....I will stick to real accent.

[@janhavikuvar173]

I am fluent in English language, but I understand every work he says…maybe you are too dumb for this lol🤷🏻‍♀️

[@vaibhavabhi1250]

Sir, Is topic pr video in hindi m bnaya

[@vijayalakshmi-wx7yg]

SOS full from enti sir

[@hussainbiology]

save our souls... an emergency signal used in Morse Code during emergency

[@vijayalakshmi-wx7yg]

@@hussainbiology thank you sir

[@hussainbiology]

@@vijayalakshmi-wx7yg you are welcome