Regulation of Gene Expression: Operons, Epigenetics, and Transcription Factors
ฝัง
- เผยแพร่เมื่อ 14 ต.ค. 2017
- We learned about gene expression in biochemistry, which is comprised of transcription and translation, and referred to as the "central dogma" of molecular biology. But how is this process regulated? How does a cell know which genes to express and when? Well it's pretty complicated, but let's just get our feet wet by looking at operons, epigenetics, and transcription factors!
Watch the whole Biology/Genetics playlist: bit.ly/ProfDaveBio
General Chemistry Tutorials: bit.ly/ProfDaveGenChem
Organic Chemistry Tutorials: bit.ly/ProfDaveOrgChem
Biochemistry Tutorials: bit.ly/ProfDaveBiochem
Anatomy & Physiology Tutorials: bit.ly/ProfDaveAnatPhys
Biopsychology Tutorials: bit.ly/ProfDaveBiopsych
Microbiology/Infectious Diseases Tutorials: bit.ly/ProfDaveMicrobio
Pharmacology Tutorials: bit.ly/ProfDavePharma
History of Drugs Videos: bit.ly/ProfDaveHistoryDrugs
EMAIL► ProfessorDaveExplains@gmail.com
PATREON► / professordaveexplains
Check out "Is This Wi-Fi Organic?", my book on disarming pseudoscience!
Amazon: amzn.to/2HtNpVH
Bookshop: bit.ly/39cKADM
Barnes and Noble: bit.ly/3pUjmrn
Book Depository: bit.ly/3aOVDlT
![[UNCUT] ฝันรักห้วงนิทรา | EP.8 (4/4)](http://i.ytimg.com/vi/RDYJYiDwsj0/mqdefault.jpg)
There should be a TH-cam university and all the best TH-cam Professors should teach there. You Sir would be one of them.
Agreed
agreed
disagreed, he didn't mention one protein/one gene
I'm sorry he did give example of genes but it hardly scratched the surface of different regulation of gene expression, where are all the lncRNA, miRNA, siRNA, different histone deacetylases and (de)methylases, cytosine methylases. No mentioning of tissue specific promotors, I don't know it just felt like a lot was missing
@@alexdeschipper it's an introduction to the topic.
Hey everyone, at 9:34 I drew a methyl group under the word acetylation and an acetyl group under the word methylation, sorry for this ridiculous error! Please correct in your minds. Oh also, I've been informed that at around 1:50, even though the labels have disappeared by that point, I previously marked the mRNA as 5' on the left and 3' on the right, and ribosomes read mRNA molecules 5' to 3', so technically the ribosome should have translated the mRNA left to right. Sorry for that small error as well!
thanks for the correction
no forgiveness 😤
you are too good.......I understood that mistake by see that. but you are too responsible.....I have no words to thank you!! GOd bless you!!!
ok daddy
I am too much pleased after hearing your lecture.Thanks sir.
This is truly amazing how complex notions can become so easy to understand when clearly explained. I’m grateful for your channel. Lots of love from France.
Je suis aussi français et je suis totalement d'accord ! (I'm French as well and I wholeheartedly agree!)
Parfaitement d’accord!!! C’est dommage que l’on est pas des aussi bonnes vidéos en français , il faudrait se mettre à la page
Pareil mdrr
You just helped me survive my O. Chem final.... now I'm discovering you cover my Genetics final too. Just... wow.
Thanks alot Professor Dave. Your teaching videos are not just clearing the concepts but arousing the curiosity to learn more about the topics.
I'm literally coming here from Khan Academy--thats how high calibre you are of an educator. To be fair, the KA video I didn't like was a one-off, as generally they are pretty good. If anyone is wondering--watch this video by Prof D instead of "Regulation of transcriptions" in the KA MCAT>Biomolecules>Gene Control.
Professor Dave out here saving my A Level Biology grade amen
Wow! I was not looking forward to even this 13 minute clip. But, WAS I WRONG. Your presentation is by far one of the best. Again, most of us are visual learners and the animation along with your teaching was spot on and kept me interested and rarely was I lost or confused. Thank you so very much!
You seriously CAN'T IMAGINE HOW MUCH I LOVE YOUR YT CHANEL. OMFG, SUCH A GOOD, "FRIENDLY" (easy to understand) AND YET ACADEMICLY SUFFICIENT CONTENT, WOW!
Im an instant new sub, keep up the excelent work!
Awesome video. Very clear and to the point. Ive been watching a lot of videos trying to wrap my head around this stuff -- this video made it stick.
I was interested in diet and people used to talk a lot about insulin metabolism at first, now I'm learning about genetics and gene expression because of research I did into the keto diet and its histone deacetylase inhibiting qualities, thank God for the internet and people like you Professor! I never really liked school but I do love learning with a passion.
Learning with passion is all you need!
bless this man and his plaid
yes
This was very short and precise. I understand clearly all that he said more than how my professor taught it. Thank you professor 🙏🏽 🤗
YOU, prof Dave, are an AMAZING teacher. Thank you so much for your videos that I will be binging as a novice neuroscience major!!!!
This is one of THE BEST biology videos on TH-cam!
hands down this is the best video on youtube of this subject man
Professor Dave! I have been watching your videos for at least a year now. You got me an A- in Gen Chem 2, are currently helping me ace Organic Chem 1, and microbiology! THANK YOU. YOU ARE THE BEST
thank you so much professor dave, you made it in a very simple explanation!
thanks professor Dave ! u made my nightly study session a lot more endurable
thank you so much~~~
This video had a lot of the details I needed to review :)
Thanks for the video. Much more direct and concise than KA. Exactly what I needed for quick review on operons for the MCAT.
What is MCAT ?
Thanks and Plz give this professor a nobel prize for making this vedio ❤️
this explanation was so great thank u professor
i enjoy your lessons alot as they have been so so helpful..keep it up
This guy and AK lectures have saved my from my profs reading slides and calling it teaching
This is the first video I’ve watched in your channel and the opening credit had me in stitches 🤣😂🤣😂
You explain so easily that even if i don't know english very well i can understand you AND the topic. Incredible thank you
Just found your channel and I absolutely love it! Very in depth videos for real science geeks! Subbed and liked!
You’re an amazing teacher, thank You so much. 👌🏻🙏🏻🙌🏻
A big fan of you sir !!
Your video tutorials helped me a loot
❤
Another wonderful session, thanks a ton
Wow this cleared so much up. Thank you!
Ugh so I took Gene expression this past fall and had to drop because I refuse to get a C in the course so I’m retaking it this spring. I so wish I found this video before because I honestly had no clue what was going on in the class, but this has helped me organize the concepts so much better! Thank you so much.
Sir u are brilliant and fabulous explainer of concepts .Thanks a lot May God bless you and keep making such videos. 😚😚
You are my secret weapon when it comes to study. :-D
Your video is so great! Thank you so much!
I love biology and chemistry
professor Dave you are a best teacher for chemistry and biology thanks for your efforts
Thank you very much for your brilliant explanation.
Beautifully clear. Thanks
Bless ur soul professor dave
this is an absolutely wonderful video specifically, thank you so much. you have no idea
Thank you so much this video really helped!!
God bless you professor, thank you for your presentation.
Damn, this is a piece of art. You teaching so much fun and. Simplified. Thanks a lot sir.
Excellent explanation, thanks again.
This is super helpful, but it would be even more helpful if you put in the corner which organisms these concepts apply to, since some of these only happen in bacteria and others in eukaryotes, and still others in both. This is something that confuses me all the time, so if you make more videos along these lines in the future, that would be very informative!
THis is explained soo good omg
This is very helpful. Keep it up! You just got my sub :)
Thank you professor. You got subscribed
this video is extremely helpful, thank u very much
This is an excellent review!
Wow! wonderful teaching Prof. Dave! More than in a University.
*I love it that this video is exactly whats in Campbell*
Very well explained!!!!
you're awesome! thanks
Is transcription a controlling factor in enzyme production for translation or transcription itself??
Great video!
Best explanation.
Nice expleined, thanks.
Awesome video! Only thing that it had acetylation with a methyl group and methylation with an acetyl group. Minute 9:38
Great work as always Dave ! A small mistake: at 1:50 translation is happening in the wrong direction, it should start at 5’
?
Yes, this is driving me nuts also. Translation starts from the 5' end with the methyl-G cap, then the mRNA feeds through the ribosome and finally the 3'-poly-A tail end comes out.
But shouldn't it go in the opposite direction. Because on the "parent" strand its 3-5 but building the opposite so thats 5-3
RNA is single stranded 🤨
Very helpful video!
Very nice video....easy to learn
Brilliant!! Thanks for this 🙏🏽🙏🏽🙏🏽
yeah
I’m literally an idiot and I understood this just fine omg dont forget your hat king 👑 😌😌
You're a great professor, your delivering techniques with clear expressional pictures makes it easier to understand things. But also suppose you're teaching someone who's being introduced to a topic the first time, you know, not to super summarize scientific concepts.
excellent prof
I've graduated HS and passed the need to study these (taking econ in college) but i still remain loyal to watching dave
More of these please
Thank you for this!
Why you explain it so much better than my textbook..
thanks so much..it was usefull for me
Awesome video!
13 minutes beat 3 hours on the official AP course.
you're the best professor !
yeah
Thanks Proff.
thanks professor dave easy to learn 😃😃😃😃😃
thankyou for the explanation
i pay my college to teach me but i always ended up on youtube because of some or so many reasons
I thought the trp operon was negative and the lactose operon was postiive ?
this is help me a lot. amazing
Really perfect explanation! I have a question, so only e.coli has operator to turn gene transcription on\off, is there also operator in human?
Thank you
Amazing sir..💖❤
Thank you so much
Thanks
sorry sir i have a problem
In an operon, the location of the regulatory region occurs before, within or after the structural genes.?????
thank for saving me
nice Rembrandt lighting
Professor kindly you may help me how to identify TF of my gene sequences or TF of my genes motifs
You're amazing.
there is a minor error in this video: at 9:37, you color coded the three groups, but they are not properly matched below.
The methyl group should be green, and the acetyl group should be red
ah man what a dumb error! thanks for catching that.
Yeah it may be alot of work to re animate the video, but you could put an annotation with the correction
good one
thank you
just loved it, such tough concepts explained cleanly ! bless professor Dave
At 9:37 the func groups for acetylation and methylation are placed in wrong order please do notice
very educational
Thank you very much Dave.. I would be like you one day .. professor.. ;)
Thankyou sir ✌