Mechanisms of DNA Damage and Repair
ฝัง
- เผยแพร่เมื่อ 11 ก.ย. 2016
- Remember how the Ninja Turtles came to be? Yes you do. It was the ooze! A radioactive ooze that mutated their DNA in just the right way to give them the ability to walk upright, talk, and do ninjutsu. Now, I'm as a big a Turtle fan as they come (Donatello is my main man) but this is a highly inaccurate way to portray mutation. Let's learn about the real ways that your DNA can become damaged, and the strategies nature has developed to combat these risks.
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I like the preschool vibes i get from the background while I'm learning stuff in my junior year of college :D it makes me feel all warm and fuzzy.
Imagine how smart preschoolers would be by watching this
@@daniellewilson8527nah preschoolers are pretty dumb. They can’t do shit
Correct.
We are all little kids deep inside.
Our official age may be 20 - 30 but we love the vibes of age 2-3 😇
"Now that we are sufficiently terrified of genetic mutations" 😂
Where did he say this lol?
@@sroydetroy6404 5:39
Àyy
Professor Dave, I'm still using your videos at Uni😂 They are so helpful. My genetics lectures are really confusing so far but this is helping consolidate my understanding. Genetics was always my week point in biology🙏🏾
Me too
I don't even have to take biology next year, but I'm forced to learn it this year ...stupid school rules...😭😭
It seems spelling is your “week” point too.
@hamzazaqut1315 omg, you need to quit your day job and become a stand up comic... you'd be a millionaire...
Dude thanks for getting directly to the point and not fluffing about like so many other youtube videos. U just feed me facts that I CRAVE!!! Professor Dave 4 prime minister 2019
Paris Coroneos exactly! He gets directly to the point
He'd probably be a 3 to 5' Minister
Thank you professor...another fabulous video. I like how you go deep down into the molecular structures of the mutant amino acids and the pyrimidine dimers (and other such things) instead of just glossing over them. Getting to the chemistry at the heart of what we observe makes the learning experience so much more intuitive!
I love how clearly you talk! great Videos
This video is great. easy to understand and have a very clear explanation! I love it
For a layman like me this series is fairly easy to follow and understand.
I am therefore very grateful and hope to be able to use your work here on Y-T a lot.
Greetzzz from Holland [sorry for my bad grammar]
Another great vid and, as always, total clarity. Thank you.
Easy to understand and informative. Thank you very much. Great job
Thank you so much Professor Dave I have an exam of Genetics this Tuesday and you have explained me about half of the themes of the exam in 11 minutes. Fantastic
Thank you so much! I couldn't understand mismatch or NER for the life of me for the entire semester. I really needed this explanation for my exam tomorrow!!
Professor Dave is one of the very few that take time to respond to the various comments😊
Love your videos to sum up what i learned in biochem :) But could you do a video about molecular cloning and PCR?
Thank you Dave for taking 🙏 the time it is appreciated much 👍
Dave, I suggest you first present a summarized outline using a flowchart classifying different mutations and its subtypes. This way it'll be easier to grasp and make notes at the same time. I suggest you apply it to other videos too
Thank you for all your tutorials! From Chemistry to Bio they all have the exact content that I need.
thank you, Professor Dave your explanations make me learn more. Thank you for producing this videos.
This video is great now u are my professor.. it’s easy to understand yr videos so simple and made with dedication and love 💕
Thank you Prof! My Go To Guy! I’ve been passing my subjs, partly bc of u! And correctly answering activity sheets because of u! THANK U SO MUCH!
Very good explanation! Thank you!
sir u are a life saver..and that intro sends ...
I love Dave so much!! The best teacher so far!!
your videos are still being used after 7 years. Thanks
He knows all about science stuff and he is professor dave explains. This song is like gangnam style. I only watched several videos and start singing when I was cooking my dinner!
cooking and singing will increase dna mutations. good luck.
just keep on cooking
Overtly, I find it annoying, but each to their own.
thank you jesu.. I mean prof. Dave this was beyond mind blowing
Don’t be shy, call him biology Jesus
Thank you prof Dave, you made me survive my journey in premed 🙏❤️
Thank you so much!! I was really looking for a class like this
Very informative, Thank you!
if this video is that informative to you, i recommend you not to take ap biology
*you helped me in biochem class thank you professor I think thank you isn't enough so grateful ❤️*
This video was tooo good! so perfect!! Thank you!!
Thanks! Great presentation, much appreciated!
hey professor dave. great video! your graphics really illustrate concepts that I've been struggling to grasp since high school. this is honestly the best explanation of mutations I've ever seen. I do have one thing I wanna clarify tho. so in the frame shift mutations, it was one whole base pair that you had deleted. let's say you showed an insertion. would it be an insertion of a whole base pair? or could you have an insertion of a nucleotide on one strand but not on the other strand opposite to that added nucleotide? let me know if my question is confusing lol I'd be happy to rephrase it as best as I can
ooh that's a good question! you know i'm not too sure, i'll have to look into that
@@ProfessorDaveExplains awesome, lemme know when ya know! and thanks again for the great vids
Thanks, Professor, for explaining it.
Nice job Dave.
This is excellent Dave, thank you!
John Bates
Very clear and concise 👍
Awesome video proffessor
brilliant. everything I needed in one video clearly explained
so great this is awesome information thank you dave
you're information is very useful
This video is great. easy to understand and have a very informative.
wow amazing proff Dave
Dave thanks so much for the videos ! Your lectures are complete and easy to understand. :)
Thank you Prof. um thinking, I may as well stop paying my school fees and start paying R5.00 per month for joining your channel, this feels great
thanks.. you explain it so clearly
Fantastic !!! really helpful
U r fabulous professor ..... u teach better than my teachers in my tutions.... Lots of love from INDIA
very good information, thanks so much
Thanks for the wonderful explain ♡
I loved the song at beginning ^_^
Dude I understand everything so well now. Thanks!
THANKS MAN, THIS WAS Helpful
It's very nice helpful. Thank you
You saved my life by this video ,thank you
Nice job, would love a homologous and nonhomologous recombination video if you have it in you
Many thanks, was great explanation.
I love you PROFESSOR DAVE!!!
Thank you Professor
Informative video.
A question :
2:27 you said if the mutation happen outside the gene it does not cause any thing
But we know that there many gene that are regulated and activated and deactivated by portions of DNA outside the gene ( epigenic )
omg very helpful.. im a big fan
....am I the only one who ALWAYS sings the intro, even though this channel has been accompanying me since my Senior year? :D
No u ain't the only one..
thank you Professor its well explained indeed
Very good teacher👌🏿👍🏿
that binding of oxidized guanine with A happens when during repair or replication as there should be C there initially ?
Bravissimo, molto belli i tuoi video, thumbs up!
"Now that we are sufficiently terrified of genetic mutations...", lol...a laugh I needed while late night studying. Thanks!
Could you gimme the details regarding the repairing enzymes?
I mean, not all of them.
But the main ones.
Very nice professor
Dave sir you r great!
شرح ظريف وممتع بالتوفيق وللامام دومااا
Really great thank you!
thank you,professor👍
@ 5:39
Dave: Now that we are sufficiently terrified of genetic mutation....
Me: guuuuuuyyyy!!!😂😂
ily dave 💖
Thanks Dave
Thank you professor
AWESOME EXPLANATION
is the polymerase used dna polymerase iii? I can never remember which polymerase is which
Super helpful
Thank you sir ❤️
U r amazing sir.....lots of love from india.....ur videos boost my knowledge🤗🙏🙏
sunscreen is only good for preventing a serious sun burn. but beside that i do not use sun screen because it reduces the vitamin d level in the body. and with a high vitamin d level there is maybe more DNA repair going on.
Thank you so much you are a life saver😟💕💕💕
As a medical student, I appreciate you, sir. You're amazing. God sent u to teach us medical contents
man, you are awesome.
the greater teacher ever
lol aced my genetics final by watching these videos... didn't go a single day to class loooool
College or high school?
you're genius. thanks for saving my life
thank you !
One of the greatest mysteries of modern science, is how does Dave have such a derpy haircut and yet manage to ooze cool from every fiber of his being?
Most likely his knowledge of his area of expertise and indeed the subject of the content, I think he uses that to stimulate people's interest and become and thus become charismatic.
Do you offer worksheets to practice and review the things you teach?
enough people have requested this that i'm thinking of doing it at some point
Do you think that if you change the dna artificialy in order to obtain a new desired characteristic (like in OMGs) the organism could try to repair the "damage" changing their structure in non certain consequences?
I'm not sure I understand the question, if you modify the genome, what precisely?
Professor Dave Explains By a gene gun, blasting DNA into other organism. Or, if I am sure, using plasmids with one or more genes that improve, for example, the resistance to some insect or extreme climate. A lot of thanks for your answers 😀
Professor Dave Explains I am trying to understand if we change artificialy a characteristic in the expresion of the DNA in order to improve our food we will have a undesirable consequence because there are is fact in the nature of the fenomena that is still not clear. For example the epigenetic or something else, maybe the relation with other microorganisms. I thought, also, that a fenotype is expresed not only with a single linear section of the code also by other parts of the code like jumps. Sorry, I hope to be enough clear. English is not my first language.
Interesting!!
Thank you, Professor! Does this mean that if you avoid sunlight, you will be healthier? Say if you just go in the morning sun for a few minutes, and then stay inside all the time? Or do we need sunlight so much that we can't avoid it, though it comes at a price?
well you need some! but excessive exposure increases the risk of skin cancer certainly. sunscreen!
Thank you! I'll remember that ;)
@@ProfessorDaveExplains What sunscreen type/spf should I choose? Do I need to apply sunscreen to all skin areas (face, neck, hands, arms, legs) exposed to sunlight or only the face? How long should I stay in the sun each day to be healthy? Thanks.
What about DNA damaged by antibiotics such as fluroquinolone antibiotics? Can it repair by itself?
so professor Dave is it true the number of mutations in human DNA makes it highly unlikely that man is as ancient a creation as we are taught and that we also have an expiration date coming up pretty soon because of those mutations?
No, that's not true, or remotely intelligible.
He always makes me smile if he pops up while I’m scrolling by lol ☺️
Really urgent doubt :
Are cytosine and cytobine the same ?
😊 music superb sir