Because when your professor studied this there is no videos he can find on the internet. Beside, school in the United States are funded by capitalists, and affected by them, they want you to spent more money on master and doctor degree and learn less than their sons and daughters which can hire primary teachers. In United States, most University be forced to promote anti-communism education other-wise those capitalists won't fund them, only MIT keep a obsecure attitude toward communism. Because if your head are normal, you should know chairman take away most benefit you made, since people study mathematics always keep the firm logic, they know capitalism is not fair, communism is needed whatever what medias and other people say.
This is the best lecture supplement - that actually provides clarity using logical sequences while retaining details pertinent for comprehension and mastery. Thank you for this resource and for providing high quality content.
TFIIB joins to the upstream of promoter at BRE region not downstream .Also TBP is a subunit of TFIID only, it comprises of two subunits , TATA binding protein (TBP) and TAFs ( TATA associated factors)
TFIIB joins upstream of PIC complex, not downstream and it’s not TFIIB sole acting here, it’s a ternary complex with base specific interactions (, not non-specific as you incorrectly stated,)with the major groove upstream (to BRE). It’s this assymetric binding of TFIIB to TBP-TATA which induces assymetry in the rest of assembly of PIC and unidirectional transcription that results.
Also TFIIB majorly stabilises melted DNA somewhat akin to row 3/4 linker in bacterial case until RNA-DNA hybrid take over. Kinda of molecular mimic to RNA
How wonderful! The transcription process has been described in detail, clearly and vividly with easy-to-remember images, with a fairly complete mechanism and very accurate and scientific information! Thank you so much!
Making a rush report regarding Transcription required a lot of time and efforts however this video save me. Thank you for this! Please continue doing so for others also.
I love it your teaching way like play kg students..I was stuck in this topic after seem this video it's totally helpful for my study.. Thank so much Sir..
Good work bro. I have this topic and my subject, but you made it really simple to do it. Okay, not “really simple” but atleast molecular biology is bearable now. 😢
no bulshit confusing grey words, no undefined word, no crappy unneccesary examples, just pure golden knowledge. love you.
Indian guys would always come to the rescue no matter what subject you are studying. thank you
Couldn't agree more
So true 😂
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How do you explain this concept so well in less than 10 minutes and my professor couldn't in two weeks?
ikr
me too XD
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Because when your professor studied this there is no videos he can find on the internet. Beside, school in the United States are funded by capitalists, and affected by them, they want you to spent more money on master and doctor degree and learn less than their sons and daughters which can hire primary teachers.
In United States, most University be forced to promote anti-communism education other-wise those capitalists won't fund them, only MIT keep a obsecure attitude toward communism.
Because if your head are normal, you should know chairman take away most benefit you made, since people study mathematics always keep the firm logic, they know capitalism is not fair, communism is needed whatever what medias and other people say.
It’s always your channel which fetches me more marks in my exams . It’s soo easy to understand rather than mugging up the entire thing
I understood everything in less than 10 minutes of my 40 pages course. You are such a good teacher ! Thank you so much !
This is the best lecture supplement - that actually provides clarity using logical sequences while retaining details pertinent for comprehension and mastery. Thank you for this resource and for providing high quality content.
I managed to pass one of the hardest exams thanks to your videos. Thank you! Greetings from Serbia🤗🇷🇸💛
Spent 40 minutes trying to get this from the textbook. Apparently, it only takes 9 minutes... thank you so much!!
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TFIIB joins to the upstream of promoter at BRE region not downstream .Also TBP is a subunit of TFIID only, it comprises of two subunits , TATA binding protein (TBP) and TAFs ( TATA associated factors)
I agree.
TFIIB joins upstream of PIC complex, not downstream and it’s not TFIIB sole acting here, it’s a ternary complex with base specific interactions (, not non-specific as you incorrectly stated,)with the major groove upstream (to BRE). It’s this assymetric binding of TFIIB to TBP-TATA which induces assymetry in the rest of assembly of PIC and unidirectional transcription that results.
Also TFIIB majorly stabilises melted DNA somewhat akin to row 3/4 linker in bacterial case until RNA-DNA hybrid take over. Kinda of molecular mimic to RNA
That what confused me in this video
How wonderful! The transcription process has been described in detail, clearly and vividly with easy-to-remember images, with a fairly complete mechanism and very accurate and scientific information! Thank you so much!
Perfect for last touch b4 exams. God job... Carry on
Thank you so much! You're helping many students around the world right now
this channel is so gonna save my ass in college
I owe my life to this person..such an amazing explaination
Making a rush report regarding Transcription required a lot of time and efforts however this video save me. Thank you for this! Please continue doing so for others also.
My Lecutre in college :-Topic Eukaryotic transcription (Blah Blah)Not understood in 1h class
But i understood very well in this 8 min video ❤️❤️🔥
The only video that helps to answer my curiosity. Thankss so much bro
I love it your teaching way like play kg students..I was stuck in this topic after seem this video it's totally helpful for my study.. Thank so much Sir..
This is amazing. You made this topic so simple and easy.
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Awesome way of teaching ❤
This vid. intrigued me watching!
Explained in a good way Thank you💯🔥
Best explanation for transcription
I've never learned anything so easily, thank you so much!!!
BRO IS LITERALLY HIM. THANK YOU.
Very nice explanation sir mnemonics are very easy to remember......well done 💪
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Beautiful and much more easy explanation.. Thanku very much sir
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Thoroughly explained!!!👍👍
Thanks a lot, It was difficult for me to study transcription in Eukaryotes.
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Very nice explanation.Helped me a lot.
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Very well described only add guanine cap is inserted in inverted position 👍 thanks for this remarkable vedio😊
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Thank you so much!!!! Amazing video. Can you please make one for translation?
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why transcription factors are in eukaryotic transcription but not in prokaryotes?
This is just perfect. Thank you so much!
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Excellent explanation thanks 😊
TFIIE and TFIIH don't bind to downstream of pol, they bind to upstream of pol, where H can phosphorylate CTD.
does al this really happen ???? i smtyms doubt, even being a science studnt.:(
order of assembly of preinitiation complex; Dogs (D) Adores (a&b) Fetching pol II (f fetch RNA pol 2) Energically (e) & Happily (h)
Is this now a gene without introns?
How does it work with introns ?
What is done first ?
a. Capping
b. splicing
c. Polyadenylation
Very informative👌😍
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That was a nice explanation. Tnq😊
Good work bro. I have this topic and my subject, but you made it really simple to do it. Okay, not “really simple” but atleast molecular biology is bearable now. 😢
Hate this topic*
Thanks a lot! You are doing an amazing job!
Help me a lot.. A big thanks for u🙏🙏
Outstanding ❤️
Superb explanation
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Great sharing
BEST CONCEPT THANKS
You made it easy to understand👌
Thank you very much
Really appreciate it
you explain it amazingly.Thank you so much