Hemophilia A - Bleeding - Most Comprehensive Explanation - Hematology, Bleeding, and Coagulation

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  • เผยแพร่เมื่อ 18 พ.ย. 2024

ความคิดเห็น • 288

  • @MedicosisPerfectionalis
    @MedicosisPerfectionalis  4 ปีที่แล้ว +16

    💊 My Antibioitcs course: www.medicosisperfectionalis.com/products/courses/antibiotics/

  • @ada8189
    @ada8189 หลายเดือนก่อน +3

    That "ohhhhhhhhhhhh" watching your videos, when it finally makes perfect sense ❤

  • @CatherineAsiimwe
    @CatherineAsiimwe 4 ปีที่แล้ว +112

    😂😂😂 this is me reading to myself when I'm studying alone

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 ปีที่แล้ว +7

      Haha 😂
      I like this method!
      Thank you so much 😊

    • @CatherineAsiimwe
      @CatherineAsiimwe 4 ปีที่แล้ว +2

      @@MedicosisPerfectionalis kindred spirits 👌👌👌🔥🔥

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 ปีที่แล้ว +2

      😊😊😊😊😊😊😊😃

    • @ArtSeeFriend
      @ArtSeeFriend 3 ปีที่แล้ว

      Me too! Trying to comprehend. This is me pictures and all!

    • @emmannishat7704
      @emmannishat7704 2 ปีที่แล้ว

      💯 Me too😂😂😂

  • @Tiffanyelizabethc
    @Tiffanyelizabethc 4 หลายเดือนก่อน +3

    I’m in PA school, and you’re breaking this down in the only way my adhd cartoon brain will absorb it-super thanks to you big boy!!!

  • @emilyfanta2386
    @emilyfanta2386 3 ปีที่แล้ว +28

    This is the first video of yours I’ve watched and I will ABSOLUTELY be sticking around for more, this is so funny and informative, I loved it!

  • @diamantejones610
    @diamantejones610 3 ปีที่แล้ว +19

    YOU ARE THE BEST! I absolutely love your videos! I have ADHD and you are the only channel that has my attention throughout Physician Assistant school! You are the best!!!!!! I can understand so much more from your videos as opposed to 2 hours of lecturing!

  • @MBOsman
    @MBOsman 2 ปีที่แล้ว +6

    Medicosis Perfectionalis is another level.
    Your are an international scholar dude.
    If you visit my village in northern Somalia, only in that village, a half of the students are just yours.
    Man, you are WELCOME to the world of your students.

  • @giovanabalbo9784
    @giovanabalbo9784 ปีที่แล้ว +4

    This is like, the best medicine channel ive ever seen! Thank you so much dude! Lots of love from Brazil

  • @Storm-vl3li
    @Storm-vl3li ปีที่แล้ว +7

    Man I hate haematology, but Alhmdulilah you made it easy for me to understand, thank you 🌷🌷🌷

  • @salmawaleed3390
    @salmawaleed3390 หลายเดือนก่อน

    We are soooo proud of you, Egyptian LEGEND 🫡

  • @sujaniwithanage2858
    @sujaniwithanage2858 4 ปีที่แล้ว +6

    You are born to teach. Its sufficient for any student to follow your videos only. Tnx

  • @muhammadkamalelqaady263
    @muhammadkamalelqaady263 3 ปีที่แล้ว +6

    انا فخور انك مصرى بجدددد

  • @peirene_mu
    @peirene_mu ปีที่แล้ว +9

    Ok, there is just no way that a non-Arab could pronounce Al-Ansari's name so perfectly

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  ปีที่แล้ว +2

      :)

    • @supermom3302
      @supermom3302 ปีที่แล้ว +3

      He is Egyptian

    • @GhadaJ
      @GhadaJ 2 หลายเดือนก่อน +2

      @@supermom3302ommggg he is????? Egyptians are the best !!!! All my fav doctor in my college are Egyptians

  • @seancady4570
    @seancady4570 10 หลายเดือนก่อน

    You are my favorite mad genius. I silently laugh at certain patho and people probably think I’m leaning toward the mad side but hey whatever works. Thanks my friend

  • @TheChloroplasm
    @TheChloroplasm 4 ปีที่แล้ว +3

    I didnt't expect that SMASH! when explaining what Emicizumab does. Gave me a little VES!

  • @prisce7642
    @prisce7642 4 ปีที่แล้ว +8

    🙌🏼🙌🏼🙌🏼🙌🏼 thank you soooo much! It’s much easier to learn with your videos!

  • @sonicwackerplush
    @sonicwackerplush ปีที่แล้ว +1

    you have a good pronunciation of the arabic name, btw your videos have helped me a lot for past few months. Thanks!

  • @exoticblondestripper
    @exoticblondestripper 3 ปีที่แล้ว +6

    absolutely looooove this lecture, soo soo creative. you pronounce Arabic sooo good, im half arabic & cant pronounce it like u, wow!!!!

  • @adecadentfairy4250
    @adecadentfairy4250 ปีที่แล้ว +2

    I LOVE how you explain stuff, always the most informative and simple presentation
    Greetings from Egypt 🇪🇬

  • @be.dentalwise
    @be.dentalwise 2 ปีที่แล้ว +4

    I like your style of teaching by giving great introduction 😁

  • @sundusfetian9427
    @sundusfetian9427 ปีที่แล้ว +1

    Why did I just had an instinct that medicosis is Egyptian guy! I'm not sure but that would definitely make me super proud

  • @prossan1612
    @prossan1612 ปีที่แล้ว +2

    اخويا فخر مصر ❤❤❤

  • @chrysanthemumjewels
    @chrysanthemumjewels 3 ปีที่แล้ว +4

    I love this so much. I laughed while learning. Well done :)

  • @AynurAwaz
    @AynurAwaz 10 หลายเดือนก่อน +1

    Dude i love u , i adore u ❤this mixing study my teacher explained it 5 times and i got nothing!!

  • @hebahussein9423
    @hebahussein9423 3 ปีที่แล้ว +3

    It is an honor to hear you pronounce the name in Arabic

  • @Wishyouendwell100
    @Wishyouendwell100 2 ปีที่แล้ว +1

    This channel is the story of how I fell in love with Patho hence Medicine too …..

  • @Dailyfusss
    @Dailyfusss 4 ปีที่แล้ว +9

    The story lines are interesting.

  • @salihayounas3259
    @salihayounas3259 7 หลายเดือนก่อน +1

    love your style of teaching❤❤ Thank you so much for this😊😊

  • @Koomson96
    @Koomson96 4 ปีที่แล้ว +2

    You are so funny! One of the main reasons why I love your videos

  • @TamaEnergy
    @TamaEnergy 3 ปีที่แล้ว +1

    you deserve more views and likes, im sure they are to come! :) thanks!

  • @DrIsmaeelSaeed
    @DrIsmaeelSaeed หลายเดือนก่อน

    I really like your way to teach ❤

  • @victoriaj4688
    @victoriaj4688 3 ปีที่แล้ว +5

    'Kiss my calcaneus' always gets me.

  • @ismailwazir8940
    @ismailwazir8940 3 ปีที่แล้ว +2

    Wonderful teaching style

  • @nerminignatova
    @nerminignatova ปีที่แล้ว +1

    You should organize a fan meeting, I'm sure there will be many people who will want to thank you in person, including me, because you're just awesome. You can put all my professors in your back pocket and sit on top of them.😂

  • @btsarianagrande1956
    @btsarianagrande1956 3 ปีที่แล้ว

    i really liked when y talked about the first doctors in history"al zahraoui ..

  • @rukiee.b.ovwigho5709
    @rukiee.b.ovwigho5709 2 ปีที่แล้ว +2

    This is truly one of the most comprehensive explanation ever. Bravo Medicosis perfectionalis 👏👏👏

  • @caterpillargirl7284
    @caterpillargirl7284 4 ปีที่แล้ว

    I thought I’d never find my Dr.Cox, but here you are

  • @PoptartToppart
    @PoptartToppart 3 ปีที่แล้ว +2

    I love your way of teaching lol! Thank you thank you!!!

  • @zaindaghestani4060
    @zaindaghestani4060 ปีที่แล้ว +1

    Ur pronunciation of the Arabic names is just greattt 😂 love it

  • @CuriousBiscuit
    @CuriousBiscuit 3 ปีที่แล้ว

    Loved the way you roasted biology teachers.
    You're an absolute legend!

  • @Zeeyyad
    @Zeeyyad 4 ปีที่แล้ว +1

    Much love, this video is both helpful and entertaining!

  • @3대50멸치
    @3대50멸치 3 ปีที่แล้ว

    I think the answer for the question is because the patient has antibody against the Factor 8. Btw your explannation is amazing. Thank you for sharing your knowledge.

  • @manaralobaidi1565
    @manaralobaidi1565 4 หลายเดือนก่อน +1

    You are the best ever❤❤❤

  • @jakevella4057
    @jakevella4057 21 วันที่ผ่านมา

    Does Desmopressin play a role in the management of haemophilia A?
    Thank you for your amazing videos as always!

  • @anieeshah4841
    @anieeshah4841 4 ปีที่แล้ว +1

    Wow u did amazing job please make more videos,i am happy that i found this channel 📚

  • @sara1363sara
    @sara1363sara 4 ปีที่แล้ว +2

    Hi.. first thanks for the amazing videos... I have a comment about the treatment of hemophilia.. It is written concentrated fact 7 but you mentioned fac 8. I know fac7 concentrate is also a treatment but just wanted to say you wrote 7 if you meant 8 and if you meant both, please add 8 as well :) One general comment: you can draw a spine or a pelvic bone rather than a long bone for "bone marrow" references :) once again, thanks! love your videos

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 ปีที่แล้ว +4

      Thank you so much, Sara!
      I meant factor 8, not 7
      Sorry about that!

    • @sara1363sara
      @sara1363sara 4 ปีที่แล้ว

      @@MedicosisPerfectionalis No worries but fact 7 concentrate is also a treatment in resistant forms, so you were technically right :)

  • @strongestinformations198
    @strongestinformations198 ปีที่แล้ว

    Nice when you talk Abu al qasim like the native Arabic people ❤😂

  • @medinatoti89
    @medinatoti89 4 ปีที่แล้ว +1

    My guess on the question is that the girl's parents both have a defect on the genetic material. Father is very likely to be hemizigous and the mother homozigous resesive.

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 ปีที่แล้ว +1

      You got part of it!
      Please see the answer in the next video!
      Thank you so much 😊

  • @brittophone6219
    @brittophone6219 2 ปีที่แล้ว

    Hi ,thanks for the mesmerising explanation!
    I have a qst , why are corticosteroids given to Haemophilic patients? Aren't they supposed to block arachidonic acid pathway by blocking phospholipase A and have antiaggregant effect on platelets therefore they worsen the hemorrhage and do not improve it !? But at the same time cortisol in high doses has a procoagulant effect! This is really confusing and contradictory 😭 can u answer that qst plz and thanks in advance

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  2 ปีที่แล้ว

      I’ve never heard of giving steroids to hemophilia patients!

    • @brittophone6219
      @brittophone6219 2 ปีที่แล้ว

      @@MedicosisPerfectionalis hmmm ,no it's not to treat the pathology (Haemophilia)itself, it's used to treat hemarthrosis for example ,by inhibiting inflammation, the paradoxical thing here is that corticosteroides inhibit platelets aggregation isn't it? So corticosteroides in this case are like a honey mixed with poison lol how can we explain this, sir, in your opinion?

  • @ganeshbhattarai4333
    @ganeshbhattarai4333 3 ปีที่แล้ว

    answer to your question is : the woman must be the carrier.Due to some causes may be the reason may be drug therapy the dominant gene gets inactivated then the recessive gene express itself and disease manifest clinically

  • @شوتغان
    @شوتغان 3 หลายเดือนก่อน

    You defendly got to be arabic to speak it like that doc😆 , love the way u do teatching greeting from 🇸🇩

  • @katambiraedmund5076
    @katambiraedmund5076 ปีที่แล้ว +1

    You are the best 😂... lemme go shine during the ward round

  • @montana9833
    @montana9833 3 ปีที่แล้ว

    Hello !!! I have some questions about hemophilia A. What do you think? Which years old the hemophilia will be disappeared.
    And what do you advise for youngers and adults to grow up brave without any pains and bevel arms or legs.
    Thanks for answer...

  • @myscene802
    @myscene802 4 ปีที่แล้ว +1

    16:02 you write there f 7 but you say true :)
    thanks for video i click when i see your notification.
    greetings from Turkey!

  • @manarsmaan2624
    @manarsmaan2624 3 ปีที่แล้ว

    Now i knew where the name Maimonides medical center in Brooklyn came from . I was going to have my rotation in Maimonides before graduation.

  • @ae8760
    @ae8760 10 หลายเดือนก่อน

    Thank you very much ❤
    and the answer still could be von willebrant disease (type 3 ) even if it is milder than hemophilia but the common is common

  • @r0or0o_101
    @r0or0o_101 6 หลายเดือนก่อน +1

    Wow, U r from Egypt ✨

  • @ayakhairy9352
    @ayakhairy9352 4 ปีที่แล้ว +2

    XLD >> Hypophosphatemic rickets
    Case scenario : it could be vwD tybe 3 i geuss

  • @No-gx2vu
    @No-gx2vu ปีที่แล้ว +1

    Heterozygous females who have randomly inactivated a higher percentage of X chromosomes with the normal gene may become symptomatic, as may homozygous females

  • @Ayça-p3e
    @Ayça-p3e ปีที่แล้ว

    Great review very informative thanx for sharing ⚘⚘

  • @My_Aim-yu4sh
    @My_Aim-yu4sh 2 ปีที่แล้ว +1

    When you get faster .....
    I cant breath 🤣
    More Thanks from my galaxy 🥰

  • @mercylinjane1111
    @mercylinjane1111 4 ปีที่แล้ว +1

    Loved the way u explained the whole concept, as well as ur cross talks.! Thanks a ton❤️❤️❤️.!!!

  • @zoejohnson5397
    @zoejohnson5397 4 ปีที่แล้ว

    on mixing studies, i think you should say that the aPTT remains prolonged (high) not low!!

  • @ayeshakhalid44
    @ayeshakhalid44 2 ปีที่แล้ว +4

    by any chance are you an arab? because the way you pronounced Abu al-qasim khalaf was WOAH.😌

  • @gracecabungcal4392
    @gracecabungcal4392 ปีที่แล้ว +1

    Hemophilia A treatment is PDF VIII concentrate ? ( typo error VII)?

  • @BrendaRweyemamu
    @BrendaRweyemamu ปีที่แล้ว

    I think the baby girl’s father is hemophilic and her mom is the carrier . Or her coagulation factor VIII is inhibited by antobody

  • @Kturpo
    @Kturpo 4 ปีที่แล้ว +2

    Thank you doctor

  • @faizaabdi1785
    @faizaabdi1785 2 ปีที่แล้ว

    Thank you very much for your effort
    God Bless you!!!!!!!!!!!!!!

  • @maanow1278
    @maanow1278 2 ปีที่แล้ว

    Factor 10 is her baby😂😂😂
    U make mi whole day

  • @drchinnyaddy
    @drchinnyaddy 3 ปีที่แล้ว +2

    the mother was a carrier and the father a sufferer ,so she got two affected X chromosomes, one from father and one from mother

  • @rathodnehal2869
    @rathodnehal2869 4 ปีที่แล้ว

    heyy 🖐️🖐️great doctor i ever seen 🙏 please you make mnemonic of clotting factor

  • @hannahrosa5485
    @hannahrosa5485 4 ปีที่แล้ว +1

    Hmmm. she has inherited an inhibitor against factor V111. Don't know. BTW your graphics are amazing. But then I am an artist and not a scientist. Different side of the brain eh! Thank you for your dedication toward teaching of everyone who comes to your site.

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 ปีที่แล้ว

      You’re very welcome, dear :)
      Thank you so much for your kind words.
      Haha 😂, yeah, different side of the brain...You’re a scientist too :)
      Regarding the question...I don’t think there’s a difference-genetically- between a deficiency and an Inhibitor...If it's X-linked recessive, then it’s X-linked recessive whether it’s a deficiency or an inhibitor.
      Can you please try again?

    • @hannahrosa5485
      @hannahrosa5485 4 ปีที่แล้ว

      @@MedicosisPerfectionalis I'll attempt it again. Her F V111c is low because she has type A, despite being female. Most people with type A are male.

    • @joliz42
      @joliz42 4 ปีที่แล้ว +2

      @@hannahrosa5485 vWD I think.

  • @mohitzambare
    @mohitzambare 3 ปีที่แล้ว

    Ehy BT is normal??? If BT is normal.. then why small cut leads to a lot of bleeding. Please reply bow I have exam tomorrow.😅😭

  • @davidwilliam5853
    @davidwilliam5853 3 ปีที่แล้ว

    Now i NEED to know where are you from .. that was PERFECT ARABIC i would be very amazed if you were not arabic yourself

  • @Atrohumter
    @Atrohumter 4 ปีที่แล้ว +1

    Very nice thank you

  • @noranmohammed8879
    @noranmohammed8879 3 ปีที่แล้ว +7

    I loved your vidoes soo helpful in pediatrics study ❤
    Are u Egyptian? The way you say abu el qasim khalaf *

  • @nourhanosama9817
    @nourhanosama9817 4 ปีที่แล้ว +1

    really useful! thank u

  • @آيهنكتلفاضل
    @آيهنكتلفاضل 7 หลายเดือนก่อน

    شكراً 🥰

  • @lovelynagrace3303
    @lovelynagrace3303 3 ปีที่แล้ว +2

    This is so much simpler than what I learn in nursing lecture 😂😂

  • @zainabh.4491
    @zainabh.4491 2 ปีที่แล้ว

    hey Medicosis! @16:35, u have mentioned the treatment to be recombinant factor 8 while writing factor 7.... it's like warfarin hypocrisy( meant to be anticoagulant but worsening DVT in HIT-2) haha....( i understand u meant it to be 8... also factor 7 helps in hemophilia a)

  • @pavanbevoor8636
    @pavanbevoor8636 4 ปีที่แล้ว +1

    Thank u so much doc

  • @silvialopez-jurado6979
    @silvialopez-jurado6979 4 ปีที่แล้ว +1

    The best videos!

  • @PatriciaNkengaNguvoLicua
    @PatriciaNkengaNguvoLicua ปีที่แล้ว +1

    why was i laughing during the whole video😂😂😂 i enjoyed it😍😍

  • @khdr4165
    @khdr4165 3 ปีที่แล้ว

    The first part of the video was just like i'm watching a comedy movie 🤣🤣❤
    But sir i didn't really understand the idea of x-linked recessive, the carrier thing and the whole mechanism i always had problems understanding those heredity-related stuff :( would you please help me with it? Or if you have a video where you elaborated a lil bit more about heredity, please put me a link 💔 and thanks alot.

  • @elle_1211
    @elle_1211 3 ปีที่แล้ว +1

    Thank you ♥️

  • @beeshoney8085
    @beeshoney8085 2 ปีที่แล้ว +1

    Yooo how did you pronounce the Arabic name so good dude

  • @aliahmedqasim9324
    @aliahmedqasim9324 2 ปีที่แล้ว

    my man minute 16:30
    in the treatment section it should be factor 8 instead of seven

  • @aroojfatima2761
    @aroojfatima2761 3 ปีที่แล้ว

    Thank you so much

  • @shalinibhandari4904
    @shalinibhandari4904 4 ปีที่แล้ว +1

    In treatment factor viii is used or vii? U r saying viii but in video it's vii showing

  • @taysseersaidawi8706
    @taysseersaidawi8706 3 ปีที่แล้ว

    Trt in hemophilia A
    Factor recombinant VIII not VII

    • @taysseersaidawi8706
      @taysseersaidawi8706 3 ปีที่แล้ว

      Trt just correct
      In trt
      Factor derived f VIII NOT VII
      YOUR ARE THE BEST

  • @AnithaS-yj3cq
    @AnithaS-yj3cq ปีที่แล้ว

    Is pencillin z contra indicated in this case?

  • @DinaAwd
    @DinaAwd 3 ปีที่แล้ว

    Yes the female can have it if the father is diseased and the mother is a carrier but this is very very rare..may be if there's consanguinity

    • @sudeavci3519
      @sudeavci3519 3 ปีที่แล้ว

      I have hemophilia and i am a female so it absolutely can :)

  • @yasmina9134
    @yasmina9134 3 ปีที่แล้ว

    Thanx alot dr

  • @missmathician_
    @missmathician_ 10 หลายเดือนก่อน

    4:22 Al Zahrawi!!!!!!

  • @tanzeelsaber98
    @tanzeelsaber98 2 ปีที่แล้ว

    Good , I like all vediow

  • @DoctorClips.
    @DoctorClips. 2 ปีที่แล้ว +1

    You are funny still 🤣🤣🤣🙌🏽

  • @عمرالسيد-خ6د
    @عمرالسيد-خ6د 2 ปีที่แล้ว

    X from mother and X from father both of them had the hemophilia a

  • @manarsmaan2624
    @manarsmaan2624 3 ปีที่แล้ว +1

    It is the first vedio we hear a little Arabic from you .😀

  • @abertbing6151
    @abertbing6151 4 ปีที่แล้ว +2

    Where are you from brother?

  • @borkboi3147
    @borkboi3147 3 ปีที่แล้ว +1

    U r amazing 🙏