Hemophilia A - Bleeding - Most Comprehensive Explanation - Hematology, Bleeding, and Coagulation

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  • เผยแพร่เมื่อ 1 ต.ค. 2024
  • Hemophilia A - Bleeding - Most Comprehensive Explanation - Hematology, Bleeding, and Coagulation.
    Hemophilia is a genetic Coagulation Disorder characterized by abnormally excessive bleeding 🩸 even after a minor scratch. Hemophilia is divided into three subtypes: hemophilia A, hemophilia B, and hemophilia C. Hemophilia A and hemophilia B are X-linked recessive, whereas hemophilia C is autosomal recessive..
    Coagulation Tests (PT, aPTT, TT, Fibrinogen, Mixing Studies,..etc).
    The coagulation factors are divided into 3 coagulation groups | Fibrinogen group, Prothrombin group, and Contact Group..
    Platelet count is one of the lab tests used by a doctor or a hematologist to assess whether your platelet number is normal, low (thrombocytopenia) or high (thrombocytosis).
    Bleeding 🩸 time (BT) is another test for platelet function.
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ความคิดเห็น • 283

  • @MedicosisPerfectionalis
    @MedicosisPerfectionalis  4 ปีที่แล้ว +16

    💊 My Antibioitcs course: www.medicosisperfectionalis.com/products/courses/antibiotics/

  • @CatherineAsiimwe
    @CatherineAsiimwe 4 ปีที่แล้ว +106

    😂😂😂 this is me reading to myself when I'm studying alone

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 ปีที่แล้ว +6

      Haha 😂
      I like this method!
      Thank you so much 😊

    • @CatherineAsiimwe
      @CatherineAsiimwe 4 ปีที่แล้ว +2

      @@MedicosisPerfectionalis kindred spirits 👌👌👌🔥🔥

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 ปีที่แล้ว +2

      😊😊😊😊😊😊😊😃

    • @ArtSeeFriend
      @ArtSeeFriend 3 ปีที่แล้ว

      Me too! Trying to comprehend. This is me pictures and all!

    • @emmannishat7704
      @emmannishat7704 2 ปีที่แล้ว

      💯 Me too😂😂😂

  • @peirene_mu
    @peirene_mu ปีที่แล้ว +8

    Ok, there is just no way that a non-Arab could pronounce Al-Ansari's name so perfectly

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  ปีที่แล้ว +2

      :)

    • @supermom3302
      @supermom3302 ปีที่แล้ว +2

      He is Egyptian

    • @GhadaJ
      @GhadaJ 29 วันที่ผ่านมา +1

      @@supermom3302ommggg he is????? Egyptians are the best !!!! All my fav doctor in my college are Egyptians

  • @emilyfanta2386
    @emilyfanta2386 3 ปีที่แล้ว +26

    This is the first video of yours I’ve watched and I will ABSOLUTELY be sticking around for more, this is so funny and informative, I loved it!

  • @diamantejones610
    @diamantejones610 3 ปีที่แล้ว +18

    YOU ARE THE BEST! I absolutely love your videos! I have ADHD and you are the only channel that has my attention throughout Physician Assistant school! You are the best!!!!!! I can understand so much more from your videos as opposed to 2 hours of lecturing!

  • @ayeshakhalid44
    @ayeshakhalid44 2 ปีที่แล้ว +4

    by any chance are you an arab? because the way you pronounced Abu al-qasim khalaf was WOAH.😌

  • @noranmohammed8879
    @noranmohammed8879 3 ปีที่แล้ว +7

    I loved your vidoes soo helpful in pediatrics study ❤
    Are u Egyptian? The way you say abu el qasim khalaf *

  • @Storm-vl3li
    @Storm-vl3li ปีที่แล้ว +5

    Man I hate haematology, but Alhmdulilah you made it easy for me to understand, thank you 🌷🌷🌷

  • @MBOsman
    @MBOsman 2 ปีที่แล้ว +6

    Medicosis Perfectionalis is another level.
    Your are an international scholar dude.
    If you visit my village in northern Somalia, only in that village, a half of the students are just yours.
    Man, you are WELCOME to the world of your students.

  • @Dailyfusss
    @Dailyfusss 4 ปีที่แล้ว +9

    The story lines are interesting.

  • @zakaryayousef
    @zakaryayousef 2 ปีที่แล้ว +2

    كفو عليك

  • @sujaniwithanage2858
    @sujaniwithanage2858 3 ปีที่แล้ว +6

    You are born to teach. Its sufficient for any student to follow your videos only. Tnx

  • @feedaanany2312
    @feedaanany2312 ปีที่แล้ว +2

    Impressive Arabic pronunciation

  • @prisce7642
    @prisce7642 4 ปีที่แล้ว +7

    🙌🏼🙌🏼🙌🏼🙌🏼 thank you soooo much! It’s much easier to learn with your videos!

  • @No-gx2vu
    @No-gx2vu ปีที่แล้ว +1

    Heterozygous females who have randomly inactivated a higher percentage of X chromosomes with the normal gene may become symptomatic, as may homozygous females

  • @gracecabungcal4392
    @gracecabungcal4392 ปีที่แล้ว +1

    Hemophilia A treatment is PDF VIII concentrate ? ( typo error VII)?

  • @exoticblondestripper
    @exoticblondestripper 3 ปีที่แล้ว +5

    absolutely looooove this lecture, soo soo creative. you pronounce Arabic sooo good, im half arabic & cant pronounce it like u, wow!!!!

  • @Tiffanyelizabethc
    @Tiffanyelizabethc 3 หลายเดือนก่อน +2

    I’m in PA school, and you’re breaking this down in the only way my adhd cartoon brain will absorb it-super thanks to you big boy!!!

  • @loly7989
    @loly7989 ปีที่แล้ว +1

    U speaking Arabic professionally
    R u Arabian ?

  • @giovanabalbo9784
    @giovanabalbo9784 11 หลายเดือนก่อน +3

    This is like, the best medicine channel ive ever seen! Thank you so much dude! Lots of love from Brazil

  • @victoriaj4688
    @victoriaj4688 2 ปีที่แล้ว +3

    'Kiss my calcaneus' always gets me.

  • @beeshoney8085
    @beeshoney8085 2 ปีที่แล้ว +1

    Yooo how did you pronounce the Arabic name so good dude

  • @ayakhairy9352
    @ayakhairy9352 4 ปีที่แล้ว +2

    XLD >> Hypophosphatemic rickets
    Case scenario : it could be vwD tybe 3 i geuss

  • @muhammadkamalelqaady263
    @muhammadkamalelqaady263 3 ปีที่แล้ว +3

    انا فخور انك مصرى بجدددد

  • @be.dentalwise
    @be.dentalwise 2 ปีที่แล้ว +4

    I like your style of teaching by giving great introduction 😁

  • @TheChloroplasm
    @TheChloroplasm 4 ปีที่แล้ว +3

    I didnt't expect that SMASH! when explaining what Emicizumab does. Gave me a little VES!

  • @chrysanthemumjewels
    @chrysanthemumjewels 2 ปีที่แล้ว +4

    I love this so much. I laughed while learning. Well done :)

  • @hebahussein9423
    @hebahussein9423 3 ปีที่แล้ว +3

    It is an honor to hear you pronounce the name in Arabic

  • @user-he9zn7qe5u
    @user-he9zn7qe5u 3 ปีที่แล้ว +1

    Let’s get married

  • @Thefable2100
    @Thefable2100 4 ปีที่แล้ว +1

    Do you have Arabic origins cause you sound Egyptian to me 😅

  • @r0or0o_101
    @r0or0o_101 4 หลายเดือนก่อน +1

    Wow, U r from Egypt ✨

  • @drchinnyaddy
    @drchinnyaddy 3 ปีที่แล้ว +2

    the mother was a carrier and the father a sufferer ,so she got two affected X chromosomes, one from father and one from mother

  • @1212T2
    @1212T2 ปีที่แล้ว +1

    Egyptian 😮😮

  • @mosab0164
    @mosab0164 3 ปีที่แล้ว +1

    4:22 YOU ARE AN ARAB

  • @zaindaghestani4060
    @zaindaghestani4060 ปีที่แล้ว +1

    Ur pronunciation of the Arabic names is just greattt 😂 love it

  • @ingridakerblom7577
    @ingridakerblom7577 2 ปีที่แล้ว

    Oh yes the qeen did not care about a son, an heir being sick....
    Did nit matter at all in the 1800's 🤦‍♀️🤦‍♀️🤦‍♀️🤦‍♀️

  • @nerminignatova
    @nerminignatova ปีที่แล้ว +1

    You should organize a fan meeting, I'm sure there will be many people who will want to thank you in person, including me, because you're just awesome. You can put all my professors in your back pocket and sit on top of them.😂

  • @e.m.g3
    @e.m.g3 10 หลายเดือนก่อน

    Bruh whattttt
    Ur Arabic is so good !!!!
    Don’t tell me u r actually an Arab !!! 😳😳😳

  • @BrendaRweyemamu
    @BrendaRweyemamu 10 หลายเดือนก่อน

    I think the baby girl’s father is hemophilic and her mom is the carrier . Or her coagulation factor VIII is inhibited by antobody

  • @شوتغان
    @شوتغان 2 หลายเดือนก่อน

    You defendly got to be arabic to speak it like that doc😆 , love the way u do teatching greeting from 🇸🇩

  • @manaralobaidi1565
    @manaralobaidi1565 3 หลายเดือนก่อน +1

    You are the best ever❤❤❤

  • @LoubnaAzzam
    @LoubnaAzzam 3 หลายเดือนก่อน +1

    ❤❤❤❤❤❤❤❤❤

  • @GhadaJ
    @GhadaJ 29 วันที่ผ่านมา

    Your pronunciation of arabic names is so good, are your arab btw???

  • @My_Aim-yu4sh
    @My_Aim-yu4sh 2 ปีที่แล้ว +1

    When you get faster .....
    I cant breath 🤣
    More Thanks from my galaxy 🥰

  • @gdsal2552
    @gdsal2552 ปีที่แล้ว

    تنطق الحروف العربيه زين هل انت مسلم

  • @DoctorClips.
    @DoctorClips. 2 ปีที่แล้ว +1

    You are funny still 🤣🤣🤣🙌🏽

  • @ismailwazir8940
    @ismailwazir8940 2 ปีที่แล้ว +2

    Wonderful teaching style

  • @AdriannyVasquez-bm6yx
    @AdriannyVasquez-bm6yx ปีที่แล้ว +1

    a funny way to learn

  • @salihayounas3259
    @salihayounas3259 6 หลายเดือนก่อน +1

    love your style of teaching❤❤ Thank you so much for this😊😊

  • @Dr_Aqsa
    @Dr_Aqsa ปีที่แล้ว +1

    Hahaha woww you make it soooo lovely 🤩

  • @sonicwackerplush
    @sonicwackerplush ปีที่แล้ว +1

    you have a good pronunciation of the arabic name, btw your videos have helped me a lot for past few months. Thanks!

  • @PoptartToppart
    @PoptartToppart 3 ปีที่แล้ว +2

    I love your way of teaching lol! Thank you thank you!!!

  • @AynurAwaz
    @AynurAwaz 8 หลายเดือนก่อน +1

    Dude i love u , i adore u ❤this mixing study my teacher explained it 5 times and i got nothing!!

  • @katambiraedmund5076
    @katambiraedmund5076 ปีที่แล้ว +1

    You are the best 😂... lemme go shine during the ward round

  • @missmathician_
    @missmathician_ 9 หลายเดือนก่อน

    4:22 Al Zahrawi!!!!!!

  • @GCM855
    @GCM855 ปีที่แล้ว +1

    Hey big boy! 😂

  • @PatriciaNkengaNguvoLicua
    @PatriciaNkengaNguvoLicua 10 หลายเดือนก่อน +1

    why was i laughing during the whole video😂😂😂 i enjoyed it😍😍

  • @farheenanwer1830
    @farheenanwer1830 7 หลายเดือนก่อน +1

    I love you

  • @Koomson96
    @Koomson96 4 ปีที่แล้ว +2

    You are so funny! One of the main reasons why I love your videos

  • @sara1363sara
    @sara1363sara 4 ปีที่แล้ว +2

    Hi.. first thanks for the amazing videos... I have a comment about the treatment of hemophilia.. It is written concentrated fact 7 but you mentioned fac 8. I know fac7 concentrate is also a treatment but just wanted to say you wrote 7 if you meant 8 and if you meant both, please add 8 as well :) One general comment: you can draw a spine or a pelvic bone rather than a long bone for "bone marrow" references :) once again, thanks! love your videos

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 ปีที่แล้ว +4

      Thank you so much, Sara!
      I meant factor 8, not 7
      Sorry about that!

    • @sara1363sara
      @sara1363sara 4 ปีที่แล้ว

      @@MedicosisPerfectionalis No worries but fact 7 concentrate is also a treatment in resistant forms, so you were technically right :)

  • @samyan_saleem4252
    @samyan_saleem4252 3 ปีที่แล้ว +1

    Wow i thought u cannot Arabic😁
    Thnx for the nice Videos

  • @abertbing6151
    @abertbing6151 4 ปีที่แล้ว +2

    Where are you from brother?

  • @hossharb
    @hossharb 7 หลายเดือนก่อน

    thanks alot arabic guy!!!!!!!!!!

  • @aponhossinniceaponhossinni2684
    @aponhossinniceaponhossinni2684 7 หลายเดือนก่อน

    My help me sir,my hemofilia man.

  • @sundusfetian9427
    @sundusfetian9427 ปีที่แล้ว +1

    Why did I just had an instinct that medicosis is Egyptian guy! I'm not sure but that would definitely make me super proud

  • @mariamkurtsadze
    @mariamkurtsadze 9 หลายเดือนก่อน

    This ironic voice is so irritating

  • @medinatoti89
    @medinatoti89 4 ปีที่แล้ว +1

    My guess on the question is that the girl's parents both have a defect on the genetic material. Father is very likely to be hemizigous and the mother homozigous resesive.

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 ปีที่แล้ว +1

      You got part of it!
      Please see the answer in the next video!
      Thank you so much 😊

  • @shalinibhandari4904
    @shalinibhandari4904 4 ปีที่แล้ว +1

    In treatment factor viii is used or vii? U r saying viii but in video it's vii showing

  • @ae8760
    @ae8760 9 หลายเดือนก่อน

    Thank you very much ❤
    and the answer still could be von willebrant disease (type 3 ) even if it is milder than hemophilia but the common is common

  • @Wishyouendwell100
    @Wishyouendwell100 2 ปีที่แล้ว +1

    This channel is the story of how I fell in love with Patho hence Medicine too …..

  • @strongestinformations198
    @strongestinformations198 ปีที่แล้ว

    Nice when you talk Abu al qasim like the native Arabic people ❤😂

  • @mohitzambare
    @mohitzambare 3 ปีที่แล้ว

    Ehy BT is normal??? If BT is normal.. then why small cut leads to a lot of bleeding. Please reply bow I have exam tomorrow.😅😭

  • @arushisharma5245
    @arushisharma5245 ปีที่แล้ว

    It is because of von willibrand factor deficiency

  • @D.yassersalah
    @D.yassersalah 2 ปีที่แล้ว

    I love you so much, unfortunately I just get to know you,,oh sooo sad.

  • @Kturpo
    @Kturpo 4 ปีที่แล้ว +2

    Thank you doctor

  • @seancady4570
    @seancady4570 9 หลายเดือนก่อน

    You are my favorite mad genius. I silently laugh at certain patho and people probably think I’m leaning toward the mad side but hey whatever works. Thanks my friend

  • @HeadFullofDreams394
    @HeadFullofDreams394 3 ปีที่แล้ว

    Maybe hemophilia is actually a curse made by an upset godmother who was uninvited to the christening party of a baby boy...

  • @prossan1612
    @prossan1612 ปีที่แล้ว +1

    اخويا فخر مصر ❤❤❤

  • @aliahmedqasim9324
    @aliahmedqasim9324 2 ปีที่แล้ว

    my man minute 16:30
    in the treatment section it should be factor 8 instead of seven

  • @Mr.C0ffee
    @Mr.C0ffee ปีที่แล้ว

    How come bleeding time is normal when hemophilia is characterized by prolonged bleeding? I get it medically but at the same time I don’t. 😂

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  ปีที่แล้ว +1

      Great question!
      Bleeding time is a measure of the function of platelets, not of coagulation factors. Hemophilia is a problem in a coagulation factor.

    • @Mr.C0ffee
      @Mr.C0ffee ปีที่แล้ว

      @@MedicosisPerfectionalis Aaahhhh! My Man! 🙌🏼 Thanks brother. Much love from Spain 🇪🇸

  • @anieeshah4841
    @anieeshah4841 3 ปีที่แล้ว +1

    Wow u did amazing job please make more videos,i am happy that i found this channel 📚

  • @عمرالسيد-خ6د
    @عمرالسيد-خ6د 2 ปีที่แล้ว

    X from mother and X from father both of them had the hemophilia a

  • @hannahrosa5485
    @hannahrosa5485 4 ปีที่แล้ว +1

    Hmmm. she has inherited an inhibitor against factor V111. Don't know. BTW your graphics are amazing. But then I am an artist and not a scientist. Different side of the brain eh! Thank you for your dedication toward teaching of everyone who comes to your site.

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 ปีที่แล้ว

      You’re very welcome, dear :)
      Thank you so much for your kind words.
      Haha 😂, yeah, different side of the brain...You’re a scientist too :)
      Regarding the question...I don’t think there’s a difference-genetically- between a deficiency and an Inhibitor...If it's X-linked recessive, then it’s X-linked recessive whether it’s a deficiency or an inhibitor.
      Can you please try again?

    • @hannahrosa5485
      @hannahrosa5485 4 ปีที่แล้ว

      @@MedicosisPerfectionalis I'll attempt it again. Her F V111c is low because she has type A, despite being female. Most people with type A are male.

    • @joliz42
      @joliz42 4 ปีที่แล้ว +2

      @@hannahrosa5485 vWD I think.

  • @Atrohumter
    @Atrohumter 4 ปีที่แล้ว +1

    Very nice thank you

  • @ganeshbhattarai4333
    @ganeshbhattarai4333 3 ปีที่แล้ว

    answer to your question is : the woman must be the carrier.Due to some causes may be the reason may be drug therapy the dominant gene gets inactivated then the recessive gene express itself and disease manifest clinically

  • @TamaEnergy
    @TamaEnergy 3 ปีที่แล้ว +1

    you deserve more views and likes, im sure they are to come! :) thanks!

  • @myscene802
    @myscene802 4 ปีที่แล้ว +1

    16:02 you write there f 7 but you say true :)
    thanks for video i click when i see your notification.
    greetings from Turkey!

  • @aliahmedqasim9324
    @aliahmedqasim9324 2 ปีที่แล้ว

    iam back although i wasnt away

  • @davidwilliam5853
    @davidwilliam5853 3 ปีที่แล้ว

    Now i NEED to know where are you from .. that was PERFECT ARABIC i would be very amazed if you were not arabic yourself

  • @yosefouad2116
    @yosefouad2116 10 หลายเดือนก่อน

    ur arabic is very good 4:20 lol

  • @آيهنكتلفاضل
    @آيهنكتلفاضل 5 หลายเดือนก่อน

    شكراً 🥰

  • @montana9833
    @montana9833 3 ปีที่แล้ว

    Hello !!! I have some questions about hemophilia A. What do you think? Which years old the hemophilia will be disappeared.
    And what do you advise for youngers and adults to grow up brave without any pains and bevel arms or legs.
    Thanks for answer...

  • @khdr4165
    @khdr4165 3 ปีที่แล้ว

    The first part of the video was just like i'm watching a comedy movie 🤣🤣❤
    But sir i didn't really understand the idea of x-linked recessive, the carrier thing and the whole mechanism i always had problems understanding those heredity-related stuff :( would you please help me with it? Or if you have a video where you elaborated a lil bit more about heredity, please put me a link 💔 and thanks alot.

  • @Dailyfusss
    @Dailyfusss 4 ปีที่แล้ว +1

    🧡🙌🏼🙌🏼love ya.

  • @sofiaahmed3872
    @sofiaahmed3872 4 ปีที่แล้ว +1

    🌺🌺🌺Nice 🌺🌺🌺

  • @DinaAwd
    @DinaAwd 3 ปีที่แล้ว

    Yes the female can have it if the father is diseased and the mother is a carrier but this is very very rare..may be if there's consanguinity

    • @sudeavci3519
      @sudeavci3519 3 ปีที่แล้ว

      I have hemophilia and i am a female so it absolutely can :)

  • @tanzeelsaber98
    @tanzeelsaber98 2 ปีที่แล้ว

    Good , I like all vediow

  • @AnithaS-yj3cq
    @AnithaS-yj3cq ปีที่แล้ว

    Is pencillin z contra indicated in this case?

  • @Zeeyyad
    @Zeeyyad 3 ปีที่แล้ว +1

    Much love, this video is both helpful and entertaining!

  • @3대50멸치
    @3대50멸치 3 ปีที่แล้ว

    I think the answer for the question is because the patient has antibody against the Factor 8. Btw your explannation is amazing. Thank you for sharing your knowledge.