I am speechless, you are brilliant. No price is enough to pay you for the work you are doing, but i just want to say thank you for sharing your phenomenal talent with us.
Thank you so much. Your videos not only teach me, they keep me on my toes to better observe and pay attention to details especially during the case studies. You're making a better med student of me everyday, I can say that for a fact.
You're the best. Never stop. Seriously. studying for NICU Certification and your videos help me more than anything. Plus you're freakin hilarious. Love it! Thank you!
I don't even know how I get here but I am beyond grateful. I've been binge watching your vids for 3 days in a row and posted it on my instagram and people go crazyyy like "what channel are you watching???"
Im studying for post graduation competitive exam..thankyou so much for such high quality teaching from standard sources....you are the best and helped me become a better doctor .
Excuses...”Ohh I didn’t study that in medical school.... professor told us to ignore this because we had a global pandemic in 2020, so we were not able to study hard”😂..... The response “You either get your head out of your sphincter or get out of this honorable profession... I demand excellence.” Day made😂 Even though you’re messing with us. Thank you for some hard truth. Excellence is important!
I'm an infectious biology student and this is not at all what i needed explained atm, but i can't click away because you're so damn funny! Keep it up!!
Hypercoagubility in nephrotic syndrome is bez of..... 1- anti coagulants prtein loss in urine (anti thrombin 3,protein c and s) so impaired fibrinolysis and. 2- bez of hyperlipidemia that damages endothelium and becomes thrombogenic and causes platelet aggregation and increased clot formation thrombus.
Everyone is probably watching Miss Universe at the moment. I'm even more grateful i'm here listening to your videos instead. 'Am excited for this afternoons class ..weeeee (a med studente here).
this big topic was explained to me by my prof like this: ‘’fibrin formation within blood vassel associated with platelets activation and consumption to be discussed with fibrinolysis’’ SO I WAS LIKE WTH! of course now it makes sense which never did before (explained by specialised haematologist) kill me! Thanks tons for your explanation
I was confused how the thrombin time and thrombocytopenia occur in DIC if there is hyper coagulation? . i think now its clear as all clotting factors are used in thrombosis and then this result in bleeding. You are awesome Mannn🔥🔥🔥🔥❤️
god you r hilarious i would be all focused with the lesson then you say something funny nd I cant stop laughing u have a bright future as a comedian if u wanted to change career one day
I am kind of confused here.Lets take an example of a woman who had an accident, unconscious and her husband said she was confused and not making any sense before taken to the hospital.Sha had a seizure. Temperature was 38.5, and a rash on her abdomen. She had extensive bruising and had been suffering from nose bleeds and headaches for a week prior to attending the hospital. PT is 14.9(control is 12.9) INR is 1.2 APTT is 37 with control 33 APTT ratio 1.1 with normal 0.8-1.2 Clauss fibrinogen is 2.3(1.5-4.5) D-Dimer is greater than 5000 Hb is 73g/l WBC 11400/L PLT is 21 LDH is 4831U/L. I thought the diagnosis would be TTP but after following this tutorial, I am not too sure. It may be CID. Please someone clear my doubts
Why does nephrotic syndrome cause hypercoagulability: here's what i understand, if my patient has nephrotic syndrome he's losing much proteins, the body needs protein and liver produces more protein, however liver doesn't produce only protein but also produces coagulation factors with it. So while the patient is busy losing proteins, he's piling up coagulation factors, that could be involved in coagulation hence HYPERCOAGULABILITY
Seondary fibrinolysis? If it’s primary it’s fibrinolysis under normal circumstances, but in secondary it’s fibrinolysis due to medical conditions or due to drug effects and stuff right? And thank you, the video is extremely good.
Sir i have a little bit confusion.. Sir DIC starts from the initiation of tissue factor that is extrensic pathway:tissue, but here aptt gets also affected that is intrinsic pathway:blood.. So Are these two pathways interdependent or these occur simultaneously in our body when there is an injury? Secondly DIC includes intravascular means it should have been started from intrinsic pathway: blood vessel? Please do reply sir
I can speak and understand english perfectly, I'm studying Medicine in french, and I have two native languages none of which are english or french, and honestly it's tiring. Bottom line is, I wish I was studying in english instead of this va-et-vient between 4 languages
In nephrotic syndrome especially in membranous nephropathy there is a loss of antithrombin 3 and protein c in urine with proteinuria due to damage in glomeruli basement membrane. Since there is loss of anticoagulants in urine so that could lead to hypercoagulation . [Source : medicosis perfectionalis]
Medicosis, why does sepsis cause insulin resistance and hyperglycemia? Is it because septic shock compromises tissue perfusion. So the tissue cannot use the insulin and sugar?
Hypercoaguable state in nephrotic syndrome causes proteinuria so at the same time there is lost of anticoagulatory proteins such as Protein S and C making it prothrombotic.
► 💊 Antibiotics Lectures: www.medicosisperfectionalis.com/products/courses/antibiotics/
You are the kind of med school professor that every student wants to pay attention to.Excellent video!!!so underappresiated yt channel
Thank you so much 😊
I am speechless, you are brilliant. No price is enough to pay you for the work you are doing, but i just want to say thank you for sharing your phenomenal talent with us.
Your kind words mean more than money :)
Thank you so much for watching!
Thank you so much.
Your videos not only teach me, they keep me on my toes to better observe and pay attention to details especially during the case studies.
You're making a better med student of me everyday, I can say that for a fact.
I am honored!
Thank you 🙏
why is this channel so under-rated?
Thank you 🙏
You're the best. Never stop. Seriously. studying for NICU Certification and your videos help me more than anything. Plus you're freakin hilarious. Love it! Thank you!
Thank you so much, Lindsay!
to understand and laugh and get motivated to study more all in one video, there must be a genius behind this video. thank u for brightening us
You're very welcome!
I really, really, really appreciate the time and effort you put into these videos. I have a heme test on Friday and your videos are truly saving me.
Glad to help!
I wish you all the success in the world!
I don't even know how I get here but I am beyond grateful. I've been binge watching your vids for 3 days in a row and posted it on my instagram and people go crazyyy like "what channel are you watching???"
Haha 😂
Thank you so much, dear :)
I am so grateful to you!
You have made me understood DIC in 25 years.Thanks
Thank you so much 😊
Nursing student here. Thoroughly enjoyed this. Thank you.
I am honored!
you are a savior specially , with the online teaching methods nowadays . thank you
Thank you 🙏
Im studying for post graduation competitive exam..thankyou so much for such high quality teaching from standard sources....you are the best and helped me become a better doctor .
Here I am a day before my MD finals. All the best.
I finally understand DIC. Thank you so much!!!!! I love the humor that you add to the video.
Thank you 😊
"the problem is inside the freaking vessel" just made me burst out laughing and i cannot explain why
Haha 😂
Excuses...”Ohh I didn’t study that in medical school.... professor told us to ignore this because we had a global pandemic in 2020, so we were not able to study hard”😂..... The response “You either get your head out of your sphincter or get out of this honorable profession... I demand excellence.” Day made😂
Even though you’re messing with us. Thank you for some hard truth. Excellence is important!
You're very welcome 😊, dear :)
Thank you so much for watching! I appreciate you!
THANK YOU!!! I HAVE NEVER ACTUALLY UNDERSTOOD DIC BUT THIS MAKES PERFECT SENSE!!
Awesome 👏
Thank you so much 😊
Strategy of videos is very very excellent!!
Glad you like them!
I'm an infectious biology student and this is not at all what i needed explained atm, but i can't click away because you're so damn funny! Keep it up!!
Haha 😂
Thank you so much 😊
I appreciate you!
I was dying, you saved me. This is God’s work!
Thank you 🙏
God bless you!
Was looking for the technical death metal song called disseminated intravascular coagulation. Now I'm a med student.
Haha 😂
Awesome 👏
you make me fall in love with med school thank youuu
My pleasure 😇
Amazing videos. Clears all the concept in the simplest possible way. Grateful to you sir.
You are most welcome!
Am a medical student 4 year and am going to watch all of this guys videos to enjoy all of his jokes
Thank you so much 😊
Never been so fast to subscribe in any channel!
Thank you so much 😊
Welcome to the family!
This is an amazing review. Some of your best work. Thank you so much!
You’re very welcome 😊
Thank you so much for watching!
woah dude, cool video. not boring at all. paying all my attention to this video, not distracted even a second. good job.
Thank you so much!
I am medico and i am perfect with ur lectures...so iam medicosis perfectionalis(proud to say)
Haha 😂
Thank you so much 😊
it is professors like these that need to get rich fast. hes so good! also im loving the tough love i needed that haha
Haha 😂
Thank you so much, Jessica!
Hypercoagubility in nephrotic syndrome is bez of..... 1- anti coagulants prtein loss in urine (anti thrombin 3,protein c and s) so impaired fibrinolysis and. 2- bez of hyperlipidemia that damages endothelium and becomes thrombogenic and causes platelet aggregation and increased clot formation thrombus.
Excellent!
Thank you
Literally interesting lectures we can divert thinking.. love from Pakistan
Thank you 😊
Everyone is probably watching Miss Universe at the moment. I'm even more grateful i'm here listening to your videos instead. 'Am excited for this afternoons class ..weeeee (a med studente here).
Wow 🤩
You’re a unicorn 🦄
Thank you so much for caring for your future patients :)
I really love it when you start your videos with cases🤩...Amazing Work !!😻
Thank you so much, bro!
I appreciate you!
My mother died from this thank you for helping me understand a little bit more
I am so sorry for your loss!
hell yeah this explains it much better than my text book. i can now follow what its saying 👍🏽
Awesome 👏
this big topic was explained to me by my prof like this: ‘’fibrin formation within blood vassel associated with platelets activation and consumption to be discussed with fibrinolysis’’ SO I WAS LIKE WTH! of course now it makes sense which never did before (explained by specialised haematologist) kill me! Thanks tons for your explanation
You’re always welcome, dear :)
I absolutely love that pep talk at the beginning 😂🤣
Haha 😂
Best video on DIC so farr !
The best educator 😂 so funny. Always keeps me engaged 😁😅
I absolutely love your roasts. You just explained this to an EMT-B.
Thank you a lot you saved my time reading a lot of books ❤️❤️❤️❤️❤️❤️❤️ and also I hope you can make more videos and help us all
Thank you so much 😊
Not only clear but also quick, thanks a lot!
First time watching your video.fantabulous.
Thank you ☺️
I was confused how the thrombin time and thrombocytopenia occur in DIC if there is hyper coagulation? . i think now its clear as all clotting factors are used in thrombosis and then this result in bleeding. You are awesome Mannn🔥🔥🔥🔥❤️
"It doesn't confirm the diagnosis
It only confirms your stupidity"
Omg lmao
Savage mode!
thank you soooo muchhhhh that was fun to watch
My pleasure 😇
god you r hilarious i would be all focused with the lesson then you say something funny nd I cant stop laughing u have a bright future as a comedian if u wanted to change career one day
Haha 😂
Thank you so much 😊
thank you Sir, big 👍🏾 from Papua New Guinea 🇵🇬. secondary fibrinolysis.
At 3:08 , if it only activates extrinsic pathway, why PTT is prolonged in DIC that is caused by amniotic fluid embolism?!
My favorite 💓💓💓
This teacher
Much love
Thank you 🙏
YOU ARE THE ONLY PERSON,EVEN IF YOU SCOLD ME I FEEL SUPER HAPPY 😂IS THIS NORMAL?
Haha 😂
Why is this dude bullying me LOL. All jokes aside, thanks man.
You’re welcome 😇
you make excellent videos sir but please explain things a tad slower, would make life so much easier.
Thank you for letting me know!
Thank you ☺️ for explaining it in simple possible words.
My pleasure 😇
AAAHH IM ADDICTED TO YOUR VIDEOS :DD
Thank you so much 😊
this is such a good case to discuss.
Thank you 🙏
Thank you, you are great !
Thank you 🙏
I am kind of confused here.Lets take an example of a woman who had an accident, unconscious and her husband said she was confused and not making any sense before taken to the hospital.Sha had a seizure. Temperature was 38.5, and a rash on her abdomen. She had extensive bruising and had been suffering from nose bleeds and headaches for a week prior to attending the hospital.
PT is 14.9(control is 12.9)
INR is 1.2
APTT is 37 with control 33
APTT ratio 1.1 with normal 0.8-1.2
Clauss fibrinogen is 2.3(1.5-4.5)
D-Dimer is greater than 5000
Hb is 73g/l
WBC 11400/L
PLT is 21
LDH is 4831U/L.
I thought the diagnosis would be TTP but after following this tutorial, I am not too sure. It may be CID. Please someone clear my doubts
Thank you very much, medicosis. You have succeeded in making me even more confused😅
Ive learned more in this 18 mins vid compared to the lectures in my uni ☠️
I am honored!
I love your videos so much i cry 😭❤
Great video as always...thank you
My pleasure 😇
Thanks 👍👍 you do a great job 🌸🌸
Thank you 🙏
Why does nephrotic syndrome cause hypercoagulability: here's what i understand, if my patient has nephrotic syndrome he's losing much proteins, the body needs protein and liver produces more protein, however liver doesn't produce only protein but also produces coagulation factors with it. So while the patient is busy losing proteins, he's piling up coagulation factors, that could be involved in coagulation hence HYPERCOAGULABILITY
This is amazing! Thank you!
My pleasure 😇
Medicosis thank you i couldn't have get it with out your videoes
You’re very welcome ☺️
Maybe loss of proteins stimulates liver to produce clotting factors to compensate
Nephrotic syndrome cause urinary loss of antithromobotic factors so it increases coagulability
Excellent!
Seondary fibrinolysis? If it’s primary it’s fibrinolysis under normal circumstances, but in secondary it’s fibrinolysis due to medical conditions or due to drug effects and stuff right? And thank you, the video is extremely good.
Thank you v.much medicosis..grateful
💕 YOU PROFESSOR
Thank you so much!
Nephrotic syndrome causes hypercoagulability because of loss of antithrombin III (loss of >3.5g/day proteins baby)
Excellent as always!
@@MedicosisPerfectionalis 🥺❤️
Sir i have a little bit confusion.. Sir DIC starts from the initiation of tissue factor that is extrensic pathway:tissue, but here aptt gets also affected that is intrinsic pathway:blood.. So Are these two pathways interdependent or these occur simultaneously in our body when there is an injury? Secondly DIC includes intravascular means it should have been started from intrinsic pathway: blood vessel? Please do reply sir
I can speak and understand english perfectly, I'm studying Medicine in french, and I have two native languages none of which are english or french, and honestly it's tiring. Bottom line is, I wish I was studying in english instead of this va-et-vient between 4 languages
m studying medecine in french as well but i always review my lessons in eng
@@sana-op4kf where u from?
Wher I can find the rest of bleeding disorder I cheeks the heamato playlist only find anemia and leukemia lymphoma
I have a separate playlist called: “Bleeding and Coagulation disorders.”
In nephrotic syndrome there is loss of protein.Antithrombin 3 protein C and protein S.Thats why it's a hypercoaguable state.
Excellent
Please, can you remind me of what antithrombin 3 is?
In chronic DIC, is the thrombosis speed slows down, and the fibrinolysis balances out the thrombosis?
In nephrotic syndrome especially in membranous nephropathy there is a loss of antithrombin 3 and protein c in urine with proteinuria due to damage in glomeruli basement membrane. Since there is loss of anticoagulants in urine so that could lead to hypercoagulation . [Source : medicosis perfectionalis]
Medicosis, I am sorry if I sound like an idiot. Why does sepsis increase tissue factor? does sepsis cause damage to the endothelium?
Hey medicosis, Is there any indication of anti coagulant in DIC? If yes, then when?
I am really grateful to you sir
Thank you so much! I appreciate you!
Would you please help me by sharing?
@@MedicosisPerfectionalis Of course.....I have already done it ❤️
I watch ur vedios every time but sorry not to comment. Thank u soooo much my doc
My pleasure 😇
Medicosis, why does sepsis cause insulin resistance and hyperglycemia? Is it because septic shock compromises tissue perfusion. So the tissue cannot use the insulin and sugar?
No sepsis cause stress stress cause corticosteroid release which cause insulin resistance
you are so amazing.. may god bless ya!! love from PAKISTAN😍
Thank you 🙏
God bless you too!
Nephrotic syndrome loss of AT-III ,protein c,s so hypercoagulable state
Is DIC considered to be connected with 2ndary Fibrinolysis since it is caused by underlying factors?
SECONDARY FIBRINOLYSIS cause 2ndary is pathological while primary is the normal fibrinolysis that happens all the time
"This will only confirm your stupidity" is good😂😂😂😂😂
I have a question.. in liver cirrhosis both PT n PTT would be elevated or just PT?
The fibrinolysis is secondary (compensatory)
obestric complication you worte Retained POC what is the full form?
Products of conception.
Hypercoaguable state in nephrotic syndrome causes proteinuria so at the same time there is lost of anticoagulatory proteins such as Protein S and C making it prothrombotic.
Professor Snape but make it Hogwarts School of Medicine👍🏾😂
You didn’t dwell on the Aetiopathogenesis
Never too late to drive for uber hahaha
😂
🤣🤣
Stupid question from a random guy just passing by and not studying medicine: can donating blood trigger DIC?
Are you asking about the donor or the recipient?
@@MedicosisPerfectionalis donor
@@ElectricityTaster no
@@h98591 cool
Thank u soooo much from egypt ❤❤
My pleasure 😇
Hi. Can DIC affects lungs? And if it does, how? Thank you so much for this. ☺ ❤️ Hoping for a response. ☺
Yes dic in alveolar capillary causes pulmonary edema followed by ARDS
Ehm... what are the requirements for Uber driver?
Just a car and a driver’s license 🤣
may i know what degrees u have? cause i love u!
I have more degrees than a thermometer 🌡 😂
Just joking 🙃
haha 😍😍😍😍😍😍