I´m in school for medical laboratory technicians and we´re getting close to our final exam, these videos are absolutely amazing and contain exactly the amount and depth of information needed :) thank you very much, it helps a lot
What's up Medicosis I'm watching this video in 2024, I guess it's one of your early videos I can see you've really come a long way and you've really improved 🤩 Keep up the good work,Doc.
I used your videos when I was at a pharmacy school now I graduated and use them to recall and teach other students :) just wanted to let you know your video will live along to many generations !! ^^ THANK YOU
I completely agree with Amanda Surujnauth from 2 years ago. Your videos are great. They are helping me complete my MLS program and prepare for the ASCP Boards.
Kristin, you’re the best! Thank you so much for your kind words! And thanks for supporting my channel on TH-cam...Thanks for clicking on the “join” button...It means the world to me!
Hey, thank you very much for these videos ❤️ But where is the video about acute intermittent porphyria? I'm asking, cause you promised us and word is word, sir 🤠 ❤️
awesome vid, again ;) binge watching all of them. NO WAY LIONEL HAS A BIOCHEM BOOK. (but is it sufficient without his videos to understand well enough?) I love you way more now.
Lionel’s books are great...Videos with the book are better...The trick in biochemistry is to take out a piece of paper and try to write down all the pathway from scratch...Then try to focus on the rate limiting steps, and the enzymes that will cause diseases when deficient! Good luck!
No, but the more you know the better...I will first start by memorizing the rate limiting step and the steps that have a disease associated with their deficiency, then I will try to add more to my memory!
Jewel from Bangladesh, taking preparation for ASCP MLT exam. Thanks 💕 for your helpful materials. Can you please make dedicated video related to ASCP MLT/MLS exam?
Thanks for your comment! Carbidopa is correct...and Levodopa is even more correct. Because when we give Levodopa and Carbidopa together, we minimize the bad effect on vitamin B6 But anyways, thanks a million! 👍
I have this doubt in head for year, have my own hypothesis but not sure, why in lead poisoning we have increase levels of ALA and protoporphyrin 9 if we inhibited 2 enzymes, I mean if we inhibited ALA dehydratase the pathway should stop here, how come it continues until protoporphyrin 9 ?
+x But, I think Levodopa is a better answer for the first one! When we give carbidopa plus levodopa together, we minimize the effect on vitamin B6! Thanks!
It was usefull to have some of the names for further research but it was a bit of a shame that the process of how, and not only under what influence the substances come to be was left out.
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Medicosis Perfectionalis thanks a lot dear
My pleasure! Please consider sharing my videos with others! Thanks 🙏
I´m in school for medical laboratory technicians and we´re getting close to our final exam, these videos are absolutely amazing and contain exactly the amount and depth of information needed :) thank you very much, it helps a lot
My pleasure 😇
Good luck 🍀
All Professors should learn from you how to teach, life would be much easier. Thank you good man.
I am honored!
Indeed I agree
🩸 Hematology Playlist: th-cam.com/play/PLYcLrRDaR8_eoNz6dxXolh1XMEietcniU.html&si=tomFsUjAgOKhOJVq
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Can anyone tell me why do we give dextrose to treat porphyrias?
The answer is in the video...Please let me know in the comments.
Because glucose and other compounds like dextrose are inhibitors of delta ala production hence porphobilinogen won't be produced.
You got it...Excellent!
I believe it slows down the reaction softens the blow. The reaction is still enevitable at some level.
Glucose inhibits the heme synthesis pathway in 1st itself.
glucose inhibits the first step, so there will be no accumulation of porphyrins
What's up Medicosis
I'm watching this video in 2024, I guess it's one of your early videos
I can see you've really come a long way and you've really improved 🤩
Keep up the good work,Doc.
Thanks!
I used your videos when I was at a pharmacy school now I graduated and use them to recall and teach other students :) just wanted to let you know your video will live along to many generations !! ^^ THANK YOU
This is amazing! Thank you so much, Sondos!
"Any doctor who diagnosis Acute intermittent Porphyria is a genius..."
Me: Write that down...WRITE THAT DOWN!!
Haha 😂
th-cam.com/video/F_EcaYEQCNk/w-d-xo.html❤️loved this video on heme synthesis
Not a "doctor" well not for humans at least, anyway going to be a Vet, your video really helped me. Thank you
Thank you 🙏
Vets are also doctors....
@@fatimarehman4900no they aren’t 😂😂😂. They eat their patients
You're a doctor too :)
You are a doctor in my heart and acedemically! my pet lived for 8 years thanks to you guys I am so grateful ❤
Love your videos! They're helping me prepare for my ASCP Boards for my MLS certification. Much appreciated!
That’s awesome...thanks for watching!
I hope you passed? I'm doing this as well.
1:52 played 50 times already😅😂(cute)
I completely agree with Amanda Surujnauth from 2 years ago. Your videos are great. They are helping me complete my MLS program and prepare for the ASCP Boards.
Kristin, you’re the best!
Thank you so much for your kind words!
And thanks for supporting my channel on TH-cam...Thanks for clicking on the “join” button...It means the world to me!
literally me LOL.
Yeahhhh. Me toooo
The drug used is L-dopa.Thanks a ton! Love from India😊
Thank you!
You called me doctor and got my heart 😂❤
You are incredibly helpful for PA school as well not just medical school. We go so fast!
I am glad to hear that my videos are helpful:)
Why I love his voice so much 😍
Thank you so much ☺️
Levodopa.
Thanks a lot doctor.
Best medicine videos on youtube.
Thank you 🙏
Carbidopa which is oftenly combined with levodopa, inhibits the conversion of B6 to PLP which is a cofactor of delta-ALA synthase.
my exams is a week away and i completely forgot all about this. thank you for refreshing my memory !
you ARE THE BEST IN TH-cam, sir, THANKS A LOT!!!!
Thank you 😊
Sir your big fan from India! Your videos are amazing! As always
Thank you so much!
Thanks mate, also didn't know that about carbidopa and b6 so I got two for the price of one.
Great :)
Nursing students watching too not only drs😌😌 helpful info thx 🙃
Thank you so much for watching 😊
Awww that word you couldn't spell for second was so cute ascent
:)
Hey, thank you very much for these videos ❤️
But where is the video about acute intermittent porphyria? I'm asking, cause you promised us and word is word, sir 🤠 ❤️
my best teacher ever❤
"Hey doctors" makes me cry i given up my dream , now im following bio medical science but I can't forget my dream😢
I think there is a little mistake.ALA dehydratase is found in the cytosol. Love your lectures!
Ur right
Yup
Is it levodopa?
You got it...Excellent
That was what I thought too. I was reading the comments to confirm lol
Levodopa...Great help thank you so much!!
I am in LOVE with your voice...
Thank you so much 😊
Loved this video on heme synthesis ❤️❤️th-cam.com/video/F_EcaYEQCNk/w-d-xo.html
Thank you so much for this.. nice voice and straight to the point
Thank you so much 😊
Not a doctor but a lab tech for the hospital, but thank you a lot anyway !
Thank you 🙏
I appreciate you!
*Thank you so much... you explained so simply* ❤❤
"Hey, doctors and future doctors"
Me a biologist: Hi
Haha 😂
Thanks bro your voice is willing to give sleep to insomaniac patient Gb
Happy to help!
Thank you very much, you are such an amazing professor
Can't wait for "doctor" to be official.
I wish you success!
I make my digital notes by screenshotting your videos and writing down your explanation
Can you please send it to me
Loved the way you started😍
Thanks 🙏
شكراً جزيلاً
The drug for Parkinson is carbidopa and levodopa.
Isoniazid, cyclosporine
These are not anti-parkinson drugs
You're great Sir 💜
Thank you so much 😊
@@MedicosisPerfectionalis my pleasure 💜
awesome vid, again ;) binge watching all of them.
NO WAY LIONEL HAS A BIOCHEM BOOK. (but is it sufficient without his videos to understand well enough?)
I love you way more now.
Lionel’s books are great...Videos with the book are better...The trick in biochemistry is to take out a piece of paper and try to write down all the pathway from scratch...Then try to focus on the rate limiting steps, and the enzymes that will cause diseases when deficient! Good luck!
do we need to know all the pathways by heart? :/
No, but the more you know the better...I will first start by memorizing the rate limiting step and the steps that have a disease associated with their deficiency, then I will try to add more to my memory!
Clear and to the point. Thank you!
My pleasure 😇
L dopa is given
N to control the action of L dopa.. we also need to give carbidopa
to inactivate comt, so happy i know these things now
Why there is no ATP consumption in heme synthesis?
Isoniazid will also inhibit B6 (pyridoxine).
Yup
Excellent as always Thank you for all the effort
+Basheer Oudah You made my day!
Levodopa will lead to protoporphyrin deficiency?
so when we say in acute intermittent porphyria there is an increase in urine porphyrins... which exactly are the "porphyrins" in this figure?
Jewel from Bangladesh, taking preparation for ASCP MLT exam.
Thanks 💕 for your helpful materials.
Can you please make dedicated video related to ASCP MLT/MLS exam?
I have 2 full playlists on “hematology” and “bleeding& coagulation” with tons of videos!
Such a hero
Thank you 🙏
Thanks a lot... Your videos are quite helpful... Please continue the good work 👍
Thank you 🙏
Thank you very much, completely well explain.
Thanks for your kind words...Good luck!
Excllent presentation. Carbidopa causes B6 deficiency
Thanks for your comment! Carbidopa is correct...and Levodopa is even more correct. Because when we give Levodopa and Carbidopa together, we minimize the bad effect on vitamin B6
But anyways, thanks a million! 👍
Can you explain why B12? Or did you mean B6 please :) If you meant B6 that's fine you dont need to explain it. -> Video -> Amazing!
Yeah...I meant B6...Sorry 😊
Thank you so much, you did help me so much🤍🤍
I am honored!
I loved you explanation well done
Keep on 🌼
+Soma Kamaran Thanks a lot! Keep studying!
Front flu volume left right cut pain.
I have this doubt in head for year, have my own hypothesis but not sure, why in lead poisoning we have increase levels of ALA and protoporphyrin 9 if we inhibited 2 enzymes, I mean if we inhibited ALA dehydratase the pathway should stop here, how come it continues until protoporphyrin 9 ?
Please which drug inhibits vit 6
Always u are te best
Thank you 🙏
Wow , really nice , Thanks alot
My pleasure 😇
carbidopa/levodopa inhibit vit b6
Levodopa drug used to treat Parkinson disease
Could i ask a question?
Why XLSA cause sideroblast anemia but other porphyria don't, they all cause decrease protoporphyrin
What’s XLSA?
@@MedicosisPerfectionalis X-link sideroblastic anemia~~
carbidopa --> B6 deficiency
+x What if the patient is treated for TB instead of Parkinson’s?
INH
+x You got both correct! You are today’s winner!
Thanks a lot for participating!
+x But, I think Levodopa is a better answer for the first one! When we give carbidopa plus levodopa together, we minimize the effect on vitamin B6!
Thanks!
thank you for making these videos. i greatly appreciate this.
Thank you so much
My pleasure 😇
just subscribed!! such a helpful series :)
Glad to have you here!
Thank you so much. You are the best ❤️
My pleasure 😇
Thanks Thanks Cleared the topic....
You’re welcome!
Very helpful , much thanks
The answer to your question, is it carbidopa and levodopa?
Levodopa 🌚
It was usefull to have some of the names for further research but it was a bit of a shame that the process of how, and not only under what influence the substances come to be was left out.
Just discovered your channel, Good videos for medical students.
Are you a doctor?
Thanks for your comment, no, I am not a doctor!
what's your field if you don't mind me asking?
Just graduated, but I am not treating patients.
The drug is carbidopa. 🤝
Thank u so much ,that was really helpful and easy way to explain this topic ❤️
Thank you so much 😊
Thank uh dude❤️
My pleasure 😇
very hard question, whats the answer ?pls
Answer to your quest : Monoamine oxidase B ( MAO B) inhibitors
Edit : I am even confused with levodopa.
Please answer your quest.
Very nice sir
Thanks dr
My pleasure 😇
At which stage of a Rbc age is heme synthesized ?.As mature Rbc's lack mitochondria how is then some part of heme synthesized in the mitochondria?.
All these steps occur in erythroblast.
Thankyouuuu🥰
My pleasure 😇
thank u so much for ur great effort .. can i ask u if u made a video for porphyria ?
Not yet.
Thanks a million!😊😊💕
My pleasure 😇
well explained
Thank You!
THANK YOUUU
Hey doctors and future doctors
AND FUTURE BIOMEDICAL ENGINEERS 😒
Welcome 🤗
that's what the future pharmacist in me thought aswell haha
😂😂
and future nurses
Yay! 😃
Welcome Welcome 🙏
You forgot to mention enzyme in step hydroxymethybilane>>>>uroporphyrinogen
True!
I was giving a quick review.
I can't thank you enough!
Of course!
Thanks a lot and I would like to know the correct answer to the question you asked in the video from you.
Levodopa/Carbidopa.
Carbidopa benserside + levodopa combinations
Thank you 🙏
anyone know the answer to the question of the day? i can't find it in the following videos?
Kindly send me an email: www.medicosisperfectionalis.com/contact/
Thank you 🙏
Thank u bro
Keep going
I will, thanks 🙏
Can you please help me by sharing?
Thanks alot
You’re always welcome :)
Thanks a lot!
My pleasure 😇
Can you please help me by sharing?
Hi if you have biochemistry notes of pharm D plzz share them
Go to my website: www.medicosisperfectionalis.com/