Medical students really need these kind of short animated videos...as they hardly get time for long 1 hour lectures...my appreciation for your smart work..keep going like this
Thank you for explaining the more complicated, in-depth concepts such as HOW the hemoglobin changes shape, instead of just saying that it does. SUPER helpful.
This is an amazing video! I dont think Ive ever remembered this much after watching a video as i did for this one, the visuals really helped! Thank you and keep up the great work!
Absolutely brilliant video!...seriously can't thank you enough!!!!! It took you 4 minutes to explain what my lecturer has tried to do in 4 2 hour lectures!
I was so confused..... as I was studying from books only n notes just imagination.... Now I see the animation n got the concept... Clear.... Thanks for your efforts.... 🙏🙏
excellent video sir I am so inspired that I have got into the glory of this life love you and your work sir always reign and inhabit this world #Bio2U Classes
This was really very good. My post doc work at Baylor college of Medicine was to generte antigen specific T cells that could differentiate between apoMb and Myoglobin in a mouse model. As ypou know the difference between apoMb and Mb is that the 2-D is the same (amino acid composition) but the 3-D is different (circular dichroism spectroscopy is different). We were able to generate T cells that could differentiate between ApoMb and Mb in a tritium based proliferation assay. This was a paper which was considered to be a classical paper that was presenred by Dr Atassi when he goit the Hardin Award in Lyon, France in 1988.
And no comment on the Bohr effect, or how those little protons change conformity? Regardless, excellent video, I haven't seen one that has gone that in depth.
Thank you, you just saved me from studying for hours on end. One question though, why do we need the non cooperative form at some point? Wouldn't it be much more efficient if it was always cooperative?
As pO2 increases, more heme groups will have coordinated with O2 molecules. Because of cooperativity between the Hb subunits, having some O2 bound will increase the affinity of the other subunits for O2, resulting in that exponential behavior for the first part of the curve. As the hemoglobins become saturated with O2, we begin to taper off, giving us a logarithmic/hyperbolic behavior, which together with the exponential 1st half forms a sigmoidal curve.
Medical students really need these kind of short animated videos...as they hardly get time for long 1 hour lectures...my appreciation for your smart work..keep going like this
Biotechnology Students approve that 🤝
Thank you for explaining the more complicated, in-depth concepts such as HOW the hemoglobin changes shape, instead of just saying that it does. SUPER helpful.
Literally the definition of high yield thank you so much!
Just about 6 minutes of a very substantial discussion. The 2hr class lecture can never lol Amazing job!
Wow, this 6 minute review took me back 15 years ago to grad school struggles to learn this stuff. Excellent!
This really simplified everything
Your way of explaining makes it all so easy to understand
Thank you
this is the shortest high yield video i have ever watched, thank you
This was amazing. THANK YOU SO MUCH I DIDNT EVEN REALIZED I WAS AS CONFUSED AS I WAS. Can you teach my biochem class instead???!?
Haha...that's what I was thinking,Alyssa!
I know right 😅😅
Really good job and deep explanation ! It's always difficult to find some explanations going so far. Most of the time it's too general: Thank you ;)
Thanks! I do my best to go as in depth as possible while keeping the videos to a reasonable length :-)
Son of a gun! this is some next level sauce
IKR
What
YEP!
Priceless.....Excellent one......Crystal Clear..God bless you
Thank you for such a great, in-depth explanation for all us medical students!
Didn't know that I could learn so much and in an easy way in only 6 minutes. Thank you!
Just stumbled on your videos as I'm going through an online, at your own pace, biochemistry class. This was very helpful, thank you!
I'm so glad to be of help ^_^ Thank you for your kind words! :-D
This is the best explanation of this topic on the internet :)
Thank you so much for the video.
Your way of explaining makes it really easy to understand.
This is fantastic! Such a great resource. You summarized a day's worth of lecture :')
Omg!! That's the best explanation of this topic on TH-cam 🤩🤩
Really good and very nicely explained.I'll recommend this video to my students. #Thanks a lot# from Bengaluru, India.
This is an amazing video! I dont think Ive ever remembered this much after watching a video as i did for this one, the visuals really helped! Thank you and keep up the great work!
WOW! Incredible how you can explain this concept and make it so easy to understand. THANK YOU!
This is the best video i get about haemoglobin😍
Absolutely brilliant video!...seriously can't thank you enough!!!!! It took you 4 minutes to explain what my lecturer has tried to do in 4 2 hour lectures!
I was so confused..... as I was studying from books only n notes just imagination.... Now I see the animation n got the concept... Clear.... Thanks for your efforts.... 🙏🙏
This video just helped me become a doctor. Thank you sir
Fenomenal video!!! You just made it perfectly clear for me, my teacher couldn’t do that in two hours while speaking about it
this was very well explained and animated! thank you so much, this really helped me.
Thanks I just remembered why I quit nursing
Honestly. Reading from the book made me so confused!! And now everything is so clear! It’s way more easy to understand from this video.
such a vast topic covered in such a brief and magnificent way!!...thanks so much !!
BRUV, YOU'VE JUST PUT MY BIOCHEM PROFESSOR TO SHAME. TOOK YOU FIVE MINUTES TO EXPLAIN HIS TWO 50 MINUTE LECTURES ABOUT GLOBINS LMAO.
Wow, what an amazing and clear explanation. THANK YOU!
Excellent presentation. Thank you.
Best video I've seen on this yet!!
Thank you so much for this, really cleared the confusion i had about these two before my biochemistry final
Such a beautiful video, couldn’t have been better❤️
Thank you for making us to understand the complicated topics in a easy way😊.
I've been saved from studying for 5 hours😭❤
incredible video! Thanks so much! I love that people put stuff out like this, it really does the world a service.
You made my all doubts clear ... thanks
My short attention span is killing me rn but this def saved me!!
Superb sir.. U have explained big biochemistry concept in just few minutes and thank you for making such videos
Great video! Thank you for helping us out! I wouldn’t understand without you👍
U were made for it, thank u👏👏👏👏👏
It is top class lecture....
omg i think i just had a nerdgasm!! bloody amazing!! i love it!! :)
excellent presentation
Such a wonderful video I have been looking for, thanks
Awesome to know the difference for better knowledge
SUCH A GOOOD VIDEO, THANK YOU!
Wow.. can't even think that this topic was soooo much confusing for me before.
Make more videos on second year biochemistry too😊
excellent video sir
I am so inspired that I have got into the glory of this life
love you and your work sir
always reign and inhabit this world
#Bio2U Classes
This was really very good. My post doc work at Baylor college of Medicine was to generte antigen specific T cells that could differentiate between apoMb and Myoglobin in a mouse model. As ypou know the difference between apoMb and Mb is that the 2-D is the same (amino acid composition) but the 3-D is different (circular dichroism spectroscopy is different). We were able to generate T cells that could differentiate between ApoMb and Mb in a tritium based proliferation assay. This was a paper which was considered to be a classical paper that was presenred by Dr Atassi when he goit the Hardin Award in Lyon, France in 1988.
That's all very swell indeed, but what exactly prompted you to write this irrelevant comment here?
@@pffa9675 😂😂
This is a great video!! Thanks so much!!
Very good explanation. Thank you
Thank you SO MUCH! This was extremely helpful and explained really complex ideas.
Thanks for your precise video
You aaree thee bestt channel everr.. Thaaank u so muuch ❤️❤️
Thank you very much .. your explanation is excellent
That was great. Thank you very much!
Excellent! Thank you. ❤
Very professional explanation!
Do courses in unis mention anything about complex ion, dative covalent bonds, ligands etc? basically a bit more chemistry insight
Great work !
That was so well made, thank you so much for your hard work
this is amazing!! i finally understand!! great job
I would appreciate it if you could talk about the fisher hypothesis on the respritory system
I like it a lot! Can you please share the references?
Thankyou so my sir
And no comment on the Bohr effect, or how those little protons change conformity? Regardless, excellent video, I haven't seen one that has gone that in depth.
Sums up my 2-hour long lecture lol. Thanks!!
Marvellous❤❤
This is amazing!
thank you for the nice explanation
Very beautifully presented
Great video as always!
Well explained ...thanku sir
thanks that was really helpful
شكرا جزيلا لك يا دكتور
ridiculously good video
Thanks so much for this explanation!
Thank you, you just saved me from studying for hours on end. One question though, why do we need the non cooperative form at some point? Wouldn't it be much more efficient if it was always cooperative?
U are amazing. Thank u so much !
this is awesome, i can't thank you enough!!
Great video! High yield!
Great video.. Can you elaborate on Tense and Relaxed forms please?
Very helpful, thanx
thank you በጣም እወድሀለሁ
Great videos! Will you please publish a series of videos on laboratory techniques in cell biology labs. Thanks
This helped a lot. Thank you:)
Great video! Pls can you explain how the pO2 exactly contributes to the sigmoidal shape of the hemoglobin function? Thank you
As pO2 increases, more heme groups will have coordinated with O2 molecules. Because of cooperativity between the Hb subunits, having some O2 bound will increase the affinity of the other subunits for O2, resulting in that exponential behavior for the first part of the curve. As the hemoglobins become saturated with O2, we begin to taper off, giving us a logarithmic/hyperbolic behavior, which together with the exponential 1st half forms a sigmoidal curve.
thank you so so much, I didnt understand what the 98% and 6% meant on my textbooks diagrams and now it makes so much more sense I feel stupid now lol
Kindly make lecture on lipoprotein metabolism
Thank you so much
🤩🤩🤩🤩🤩🤩😍
Breath of life
Wow wow wow
This is pure gold
Could you do a video on protein folding?
Very good video but it ia ganna be nice if your take caption for arabic language in the next video
@2:53 you meant to say ' chain of conformational changes in the adjacent "myoglobins" '?
Thanks a million!