In this video, Dr Matt explains the receptors that acetylcholine bind to. These receptors are classified into nicotinic and muscarinic receptors and located in very distinct regions of the body.
thank you for simplifying this! its not as overwhelming when broken down like this. i feel as though i should be sending my financial aid to you and dr. mike instead of my nursing program lol. much appreciation from the states.
so helpful. NP student studying for pharm and I come back to youtube to review the basics and your videos truly relieve my anxiety when I'm not understanding something. thank you so much!
Thank you so much for the video Dr Matt! I have always found this topic a bit intimidating. I thought it was too difficult but you made everything easier to understand! When I want to revise, I always check if you guys have a video about it and watch your lectures first because you guys make everything simpler and easier to understand. Thank you so much!
Hi Dr. Matt, Thank you so much for this video! I finally understand what the muscarinic receptors do. I'm a nursing student... your videos are just great. thanks for everything.
I believe it would enhance our understanding of the muscarinic receptors with a study of the physiological effects of antagonists blocking them or if for some reason they are disfunctional. Side effects may include..
The nicotinic receptors are important when we talk about smoking behavious. People with CHRNA3 CHRNA5 and other nicotinic receptor mutations become heavy smokers if they start to smoke, they cannot quit and they get really mad when they want to smoke and they have no cigarettes. They have terrible withdrowal symptoms such as extreme anger and uncontrolled behaviour.
In your illustration, the preganglionic is shorter than the postganglionic. The preganglionic should be longer than the postganglionic in the parasympathetic division.
*M1* _(present in brain and stomach)_ and *M3* _(in glands and throuout the body in smooth muscle)_ are *stimulators* while *M2* (heart) is *inhibitor.* Therefore, ACh thouout the body may cause DUMBBEL (12:35)
Very good, but I don't understand how you can include nicotinic receptors innervating skeletal muscle in with the parasympathetic system. What am I missing here? I thought the control of skeletal muscle was outside the autonomic nervous system. Or were you just mentioning the NM receptor just to be complete about nicotinic receptors?
Plz help me to clarify this, Sphincters in the GIT are relaxed under parasympathetic NS. But these smooth muscles in these sphincters have M3 receptors (they are Gq receptors and doing some kind of stimulatory action ) So these muscles should be constricted as I feel 🤔 I can't understand this theory!
U guys are the saviour of medical students journey
This antagonizes my conviction that physicians should be teaching pathophysiology and pharmacology to RN students. Excellent teacher.
You explained it so well and so simple while still covering all the important information. My hero!!
Coming in clutch for COVID cancelling lectures!
thank you for simplifying this! its not as overwhelming when broken down like this. i feel as though i should be sending my financial aid to you and dr. mike instead of my nursing program lol. much appreciation from the states.
This is such a clear video with all the important information- thank you so much for making this!!
a work of art! excellent explanation!!
Also S for salivation in DUMBBELS cuz I listened to the podcast about Cholinergic receptors. I love you guys and your efforts. Thank you so much 😭❤️
Excellent video... thank you so much, Dr. Matt 😃
Amazing explanation, kudos to Dr. Mike and Dr. Matt, both of you are great talents and thank you for sharing your knowledge through youtube.
Doing first year med in Aus and these videos are a lifesaver
Great video!!! have been struggling to understand the whole concept. its all clear now!!! Thanks
Thank you, Dr.
Amazing video , very informative and easy to understand , thank you !
Fantastic lecture! I had a patient on an anticholinergic drug and I couldn't remember the effects of cholinergic receptor stimulation. Thanks.
so helpful. NP student studying for pharm and I come back to youtube to review the basics and your videos truly relieve my anxiety when I'm not understanding something. thank you so much!
I’m first year college 😂
we love you!! this is great!
These are so good thank you!
Thanks so much for this video! It's super helpful!
Thank you doctor matt
You are better than my lecturers ...
Actually the preganglionic neuron in parasympathic system is longer than the postganglionic neuron
Such a great video, thank you! Very easy to understand and follow along :)
You are very great teacher for physiology!❤ thx u.❤
thank you doctor for the good work
Awesome video. Thanks🙏
Thank you so much for the video Dr Matt! I have always found this topic a bit intimidating. I thought it was too difficult but you made everything easier to understand! When I want to revise, I always check if you guys have a video about it and watch your lectures first because you guys make everything simpler and easier to understand. Thank you so much!
Agree!
This is the core issue in my state . TY. Tomorrow .
great video!
you guys are superb in every lecture!! thank you for making my A&P life easier!!!!
Thank you, so much
Great Job
Fantastic
Thanks uuu , doctors 💎💎💎
Ahhh it all makes so much sense now!!!
amazing explanation
Hi Dr. Matt, Thank you so much for this video! I finally understand what the muscarinic receptors do. I'm a nursing student... your videos are just great. thanks for everything.
Thanks for your explanation
😍😍😍
I believe it would enhance our understanding of the muscarinic receptors with a study of the physiological effects of antagonists blocking them or if for some reason they are disfunctional. Side effects may include..
Please elaborate i wanna understand.
@@user-rp2ui8ro4r what's your story ? .. why the interest ?
Shouldn't the parasympathetic preganglionic neuron be long? and the postganglionic be short?
Yup
confused me for a sec as well
thank yaaa❤
thank you 😭❤️
Thanks!
Thank you sir love from india
The nicotinic receptors are important when we talk about smoking behavious. People with CHRNA3 CHRNA5 and other nicotinic receptor mutations become heavy smokers if they start to smoke, they cannot quit and they get really mad when they want to smoke and they have no cigarettes. They have terrible withdrowal symptoms such as extreme anger and uncontrolled behaviour.
👏🏻👏🏻👏🏻👏🏻👏🏻 thank you
Awesome video !! 👏👏 but why we have a broncho-secretion with M3 receptors ?! What's the goal ?!
BIG THANK YOU SIR! YOU SAVE MEEEE
thank u
Thank youuuuu.
Thanks alot
Awesome ❤❤❤❤❤
In your illustration, the preganglionic is shorter than the postganglionic. The preganglionic should be longer than the postganglionic in the parasympathetic division.
yeah. should be the other way
*M1* _(present in brain and stomach)_ and *M3* _(in glands and throuout the body in smooth muscle)_ are *stimulators* while *M2* (heart) is *inhibitor.* Therefore, ACh thouout the body may cause DUMBBEL (12:35)
for parasympathetic NS, shouldn't the preganglionic neurons be longer than postganglionic?
Hi! I'm sorry, but can you say why you draw preganglionic neurons this short? maybe that not that important. Anyway, awesome videos, thank you
Co-ask
Very good, but I don't understand how you can include nicotinic receptors innervating skeletal muscle in with the parasympathetic system. What am I missing here? I thought the control of skeletal muscle was outside the autonomic nervous system. Or were you just mentioning the NM receptor just to be complete about nicotinic receptors?
Wao 👍
Hi sir ! This is med student from India . Kindly add video on adrenalic system.
How does anyone take control of the autonomic nervous system ? Drugs ? Breathing ? Electricity ? All of this seems hypothetical
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🔥🔥
Plz help me to clarify this, Sphincters in the GIT are relaxed under parasympathetic NS. But these smooth muscles in these sphincters have M3 receptors (they are Gq receptors and doing some kind of stimulatory action ) So these muscles should be constricted as I feel 🤔 I can't understand this theory!
Did you find an answer?
💓💓💓
Why were the preganglionic neuron long
life saveerrrr
bored with the simplicity in LPN program. I come here to actually learn how it works.
parasympathetic have longer pre ganglion..
What does D denotes in DUMBBEL???
Diarrhoea and drooling