Nicotinic vs Muscarinic Receptors

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  • เผยแพร่เมื่อ 24 พ.ย. 2024

ความคิดเห็น • 254

  • @MedicosisPerfectionalis
    @MedicosisPerfectionalis  4 ปีที่แล้ว +19

    💊 Autonomic Pharmacology: www.medicosisperfectionalis.com/

    • @LetsGoTech
      @LetsGoTech 2 ปีที่แล้ว +1

      Thanks for summarizing my pharmacology exam

    • @Dr_strange_2652
      @Dr_strange_2652 ปีที่แล้ว

      Boss please make all videos uploaded in TH-cam 😊

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  ปีที่แล้ว

      @@LetsGoTechMy pleasure!

  • @richardgriggs8525
    @richardgriggs8525 2 ปีที่แล้ว +85

    I'm legit 60 seconds in and already this makes sense. My med school professors are world leaders on the ANS but can't be bothered to state the most foundational things in a straightforward way.

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  2 ปีที่แล้ว +3

      Thank you so much 😊 for watching!

    • @robertbruhcuh3634
      @robertbruhcuh3634 ปีที่แล้ว

      they don’t know lmao it’s most people especially teachers not college some college im pretty sure actually learn what they teach

  • @cardamomes
    @cardamomes 2 ปีที่แล้ว +27

    Absolute perfection. Suddenly years of lectures makes sense in one video.

  • @grayhero1
    @grayhero1 3 ปีที่แล้ว +25

    I'm preparing myself for my Pharmacology exam,and I watch your videos to give every topic a beautiful start,i know no means to say how useful these videos are.thank you MP.

  • @jacobbryan4875
    @jacobbryan4875 2 ปีที่แล้ว +56

    One of the best explanations out there on this topic! Thanks a lot.

  • @jennaalqdah9538
    @jennaalqdah9538 วันที่ผ่านมา

    You're always gonna be the best teacher for med stuff. Thank you for helping me get through this.

  • @jonquilsimms97
    @jonquilsimms97 3 หลายเดือนก่อน +3

    Im a P1 student in Principles of Pharmacology and this definitely helped me to wrap my mind around what the receptors do omg. Thanks so much!

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  3 หลายเดือนก่อน

      You're very welcome, dear!
      I wish you all the success in the world!

  • @sobster123
    @sobster123 2 ปีที่แล้ว +13

    I've *always* struggled with pharmacology. Especially this topic. But my God. The way this GENIUS explained this. ❤️I could give him my soul. The best teacher ever. Thank you *so* much Mr Perfectionist.💞

  • @MedicosisPerfectionalis
    @MedicosisPerfectionalis  ปีที่แล้ว +3

    🧠 Neuroanatomy Playlist: th-cam.com/play/PLYcLrRDaR8_cBHy0sWaCaLmOlJb9gzmA2.html&si=lnnSJhJJTUcfKl5b
    🥼 Clinical Neurology Playlist: th-cam.com/play/PLYcLrRDaR8_cQG-7JbGaeXsXGgBpK-Yzl.html&si=Qoi97evsN9uz-9Te
    💀 Anatomy Playlist: th-cam.com/play/PLYcLrRDaR8_cxbxAwLSQSx9v28Ezv3gQB.html&si=jqigBoyauPcen27C

  • @danicahashimoto9833
    @danicahashimoto9833 10 หลายเดือนก่อน +4

    I never comment on videos but I have to say this is one of the most helpful videos!! Taking my boards for becoming a Physician Assistant (PA) and these concepts always went over my head. So important to nail it down for all the pharmacology and functions. Thank you for this!!

  • @MedicosisPerfectionalis
    @MedicosisPerfectionalis  ปีที่แล้ว +2

    👨‍🏫 Physiology Playlist: th-cam.com/play/PLYcLrRDaR8_eAjmngd289ghWijs2wfqnj.html

  • @afifahbasirun3586
    @afifahbasirun3586 3 ปีที่แล้ว +28

    Thank you so much.
    This is very helpful, it feels like you're slapping my brain with knowledge from my lectures but with more sense!!

  • @ShinigamisBlade
    @ShinigamisBlade 9 หลายเดือนก่อน +12

    Prepping for a test and the jokes are keeping me alive 😂

  • @sherihanalmohammad7195
    @sherihanalmohammad7195 2 ปีที่แล้ว +2

    this is by far the mosssssssssssssst useful piece of info I've found on TH-cam or any other platform, with the best way to put it out
    wow, I still can't believe I've found you!
    Thankssssssssssssssssss

  • @هلالالحميري-د5ض
    @هلالالحميري-د5ض 4 ปีที่แล้ว +34

    We are relly grateful for u sir,plz keep going ,I like the way that u explain, u make every thing easy ...thank u so much

  • @KyleRayner12
    @KyleRayner12 4 ปีที่แล้ว +9

    Thanks for explaining. You covered this better in 0.25 hr than my professor did in 1.5.

  • @oliviam1999
    @oliviam1999 4 ปีที่แล้ว +7

    thank you so much for explaining clearly, i love being explained to like i know nothing because i really know nothing

  • @kdee7891
    @kdee7891 7 หลายเดือนก่อน +3

    I wish our professors would come to class and just tell us to watch these videos and close us for the day. Because this makes waaay more sense than sitting in a 3hr lecture

  • @siddhantpandey4903
    @siddhantpandey4903 6 หลายเดือนก่อน +2

    Helped me to clear veterinary pharmacology doubts

  • @leobesa2887
    @leobesa2887 4 ปีที่แล้ว +42

    Don't watch this at 1.5x speed

    • @Amerah-hs6ks
      @Amerah-hs6ks 7 หลายเดือนก่อน +4

      This is literally what I intended to do🤣🤣💔

    • @choco_n0183
      @choco_n0183 หลายเดือนก่อน

      @@Amerah-hs6ks+

  • @depharmily2064
    @depharmily2064 4 ปีที่แล้ว +8

    THAT WAS FUNNY AND INFORMATIVE , THANK YOU SO MUCH, MUCH LOVE FROM SOUTH AFRICA

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 ปีที่แล้ว +1

      You’re very welcome 😊
      Thank you so much for watching!
      I am honored!

  • @Melissa-S
    @Melissa-S ปีที่แล้ว +1

    NO OTHER WORD TO DESCRIBE THIS THAN BRILLIANT!!!

  • @rashialimbona1078
    @rashialimbona1078 2 ปีที่แล้ว +3

    This is the first time I've watched your videos and I love it already. New subscriber gained!

  • @jenniferhoule3233
    @jenniferhoule3233 2 ปีที่แล้ว +3

    Wow! thank you so much! I finally understand What my professor was talking about!! Amazing explanation!!!!

  • @mohdusman2436
    @mohdusman2436 3 ปีที่แล้ว +4

    Man this stuff is going straight up in my brain in a easy way 🧠 thanks 🙏

  • @WookieWoman
    @WookieWoman 4 ปีที่แล้ว +9

    I learn so much from you that maybe I should start actually studying some form of medical science...

  • @pinklavender1719
    @pinklavender1719 ปีที่แล้ว +2

    thank you for making it easier to understand!!!

  • @karamabbas2922
    @karamabbas2922 3 ปีที่แล้ว +2

    you are the god of teaching i hope if you were the president of education in the world

  • @romuellebarbado2088
    @romuellebarbado2088 3 ปีที่แล้ว +5

    watching this before I take my quiz and it really is a huge help. Thank you sir

  • @handsomejohnjohn
    @handsomejohnjohn 2 ปีที่แล้ว +1

    Great video. A sense of humor helps. Thank you

  • @shadowkokufu9178
    @shadowkokufu9178 ปีที่แล้ว +1

    Really enjoying this - I'm using these videos to get that foundation and then going to my pharms notes and trying to predict the drug actions based off the receptor (need practice). Thanks!!
    Plus I'm watching this clip and my brain is filling in the blanks that you spoke of in other videos. The way that you do this makes stuff stick in my head. Thanks!!

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  ปีที่แล้ว +1

      I am honored! I've covered more autonomic pharmacology in my pharmacology playlist;
      th-cam.com/play/PLYcLrRDaR8_d5RzuEJprW-NWXTK22ByVC.html&si=6_bmiW838rUPzL3y

    • @shadowkokufu9178
      @shadowkokufu9178 ปีที่แล้ว

      @MedicosisPerfectionalis Thanks!! I'm studying for my pharms test next week, so I'll definitely be going through there amongst other playlists. Thank you for the link!!

  • @alexsheremett3097
    @alexsheremett3097 5 หลายเดือนก่อน +1

    Get tired to be amazed. ... Thanks for the lesson❤

  • @Shambhaviak
    @Shambhaviak 4 ปีที่แล้ว +6

    Thank you so much!
    This was such a comprehensive and informative video
    I learnt the topic well :)

  • @morganswanger6154
    @morganswanger6154 10 หลายเดือนก่อน +2

    Dude you're hilarious. I would watch this instead of a netflix show.

  • @husniyamuhalim5703
    @husniyamuhalim5703 3 ปีที่แล้ว +4

    I am having a hard time understanding this topic but thanks you sir, I got a hang of it.

  • @clarkkent4872
    @clarkkent4872 3 ปีที่แล้ว +3

    Thank you so much. I wish I have found this channel earlier.

  • @harineepriya
    @harineepriya 2 ปีที่แล้ว +2

    Thank you for this awesome video.

  • @Muuip
    @Muuip 2 ปีที่แล้ว +1

    Great concise presentation!
    Much appreciated!👍👍👍

  • @serotoninteam3866
    @serotoninteam3866 ปีที่แล้ว

    i cant thank you enough medicosis

  • @soulhunter4739
    @soulhunter4739 3 ปีที่แล้ว +2

    thanks alot sir today is my pharmacology paper & it helped me alot🖤❤️

  • @alaamahmoud6625
    @alaamahmoud6625 3 ปีที่แล้ว +2

    Amazzzzing simple and to the point thanks a lot

  • @marryhawar4568
    @marryhawar4568 2 ปีที่แล้ว +1

    Thank you so much! You explained in the best way .. but.. I think M2 receptor doesn’t cause decrease in heart contractility .. please tell me if I’m wrong

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  2 ปีที่แล้ว +1

      You're right. M2 is present more in the atria than ventricles. So they work on decreasing heart rate, not necessarily contractility.

  • @erraticansh8459
    @erraticansh8459 4 ปีที่แล้ว +3

    You're underrated.

  • @UmmerFaseel
    @UmmerFaseel 7 หลายเดือนก่อน +1

    Excellent video to learn basics of psychopharmacology ( Not all intelligent people can teach - that requires talent too 👍 & you are awesome 👍 Keep going my friend).

  • @MyNameisDianaa
    @MyNameisDianaa 4 ปีที่แล้ว +3

    Just in time for my Pharmacology birthday test!!

  • @Sama-Rose
    @Sama-Rose ปีที่แล้ว +1

    It is just amazing !! thank you
    how can we be like you one day ( a super doctor) ??!!

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  ปีที่แล้ว

      Wow, thank you!
      Work hard every day for the next 10 years and you'll be way better than me!

  • @tabassum3501
    @tabassum3501 3 ปีที่แล้ว +3

    Loved the way u explained👍😊

  • @Kynxs
    @Kynxs หลายเดือนก่อน

    I’m watching the M1 B1 M2 AND THIS MAN IS COOKING WOTH THE ANALOGIES

  • @Yan-e5u
    @Yan-e5u ปีที่แล้ว

    Why is it that when someone is equally startled or nervous, they sometimes turn pale, while other times they blush? And why do people experience alternations of turning pale and blushing when they're embarrassed?

  • @klayman6670
    @klayman6670 2 ปีที่แล้ว +1

    Hello bro, I have a question where are nicotinic receptors most dense and where are muscaranic receptors most dense?

  • @preethamyadav8907
    @preethamyadav8907 4 ปีที่แล้ว +1

    Sir ,pls explain in detail case presentation of ENT,Ophthal,community practical exam cases.pls do reply.pls share it with us the case presentation.

  • @collho
    @collho 3 ปีที่แล้ว +5

    This is brilliant!! Thank you :)
    As a added benefit, you are also HILARIOUS :D

  • @thegreatpogi
    @thegreatpogi 3 ปีที่แล้ว +10

    This guy making me laugh so hard and learning at the same time hahahaha! But fr though I got an upcoming board exam this march 10 and im weak at pharmacology but woah! The way you make fun of pharmacology is what makes me understand so much easier! Trust me ive learned a lot from you already thank you my man!!!!

    • @thegreatpogi
      @thegreatpogi 3 ปีที่แล้ว +3

      Btw I subscribed hahahaha love from future philippine pharmacist here!

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  3 ปีที่แล้ว +1

      Wow 🤩
      Thank you so much 😊
      Good luck 🍀 to you!

    • @thegreatpogi
      @thegreatpogi 3 ปีที่แล้ว +1

      @@MedicosisPerfectionalis you're very welcome! And all of your efforts are appreciated! Especially the "running from the tiger" shut them all dooooown!!! (Any shits that's not a necessity for running HAHAHAHAH) thank you rly thank you!

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  3 ปีที่แล้ว

      You’re very welcome 😊

  • @leagueofcow6403
    @leagueofcow6403 2 ปีที่แล้ว +3

    Thank you so much!! truly amazing

  • @jmw77
    @jmw77 ปีที่แล้ว +3

    08:20 "why didn't we call it f protein as in F U" lmao I needed that

  • @nikolakulik824
    @nikolakulik824 3 ปีที่แล้ว +1

    Am I right that M3 receptors are stimulated in skeletal muscle vessels during exercise and cause vasodilation as a part of sympathetic response?

  • @NERVESMEDICINE616
    @NERVESMEDICINE616 4 ปีที่แล้ว +2

    Wow brother, its great to see your video
    Doing great work 👍

  • @matiullah757
    @matiullah757 2 ปีที่แล้ว +2

    What a lecture,u make my day😂🤓👏🏼✌

  • @jemjem1801
    @jemjem1801 3 ปีที่แล้ว +2

    The best as usual ☺️

  • @arjunbaburaj3402
    @arjunbaburaj3402 2 ปีที่แล้ว +1

    Such a wonderful explanation...thank you so much @Genius

  • @gunjansharma9441
    @gunjansharma9441 3 ปีที่แล้ว +1

    Why does Nicotinic cholinergic blocker causes paralytic asphyxia without heart failure?

  • @eddiedavisjr9771
    @eddiedavisjr9771 2 ปีที่แล้ว +1

    This was wonderful.

  • @IbiDon
    @IbiDon ปีที่แล้ว +2

    This guy is Pharmacologys kryptonite.

  • @lillaramonda
    @lillaramonda 2 ปีที่แล้ว +3

    Hahahahahaha okay this guy is crazy 🤪 Thanks a looot 🤩
    And now baby I'm depolarized... 😍😎🤭

  • @farahmedhat2891
    @farahmedhat2891 3 ปีที่แล้ว +2

    Great effort, thank you 😊 👏

  • @sukhveerkaur1390
    @sukhveerkaur1390 3 ปีที่แล้ว +2

    Thanku so much 😀sooooo helpful , great work 👍

  • @laibakhan4186
    @laibakhan4186 2 หลายเดือนก่อน

    it says that M2,M4 work through Gi which inhibits parasympathetic(6:47), but moving forward you mentioned that it decreases contractility of heart etc. could someone please explain what this means

  • @ruqaya7401
    @ruqaya7401 2 ปีที่แล้ว +2

    Great video thank you so much ❤️ 🔥

  • @wongno8986
    @wongno8986 ปีที่แล้ว +1

    thank you so much it helps a lot!

  • @MsPlus24
    @MsPlus24 3 ปีที่แล้ว +3

    Ahhhh sooo beautifully explained!!!

  • @عمرالطائي-ح7ب
    @عمرالطائي-ح7ب 3 ปีที่แล้ว +2

    Thank you so much my Dr

  • @zainabfarooq5263
    @zainabfarooq5263 2 ปีที่แล้ว +1

    Great work

  • @franzsikaschulze8846
    @franzsikaschulze8846 ปีที่แล้ว

    boy, didnt find a video in my language about that topic and now I have to understand in English ._. still thankful XD

  • @sarahhammo8496
    @sarahhammo8496 3 ปีที่แล้ว +2

    beyond amazing!

  • @konstantinsinichkin8855
    @konstantinsinichkin8855 10 หลายเดือนก่อน

    fly agaric helps to quit smoking?

  • @snoviasingh884
    @snoviasingh884 3 ปีที่แล้ว +4

    I imagine the nicotinic receptor scream aggressively IM SICK AND TIRED OF BEING SICK AND TIRED XD

  • @babyjanefabrigas6336
    @babyjanefabrigas6336 2 ปีที่แล้ว +2

    Thank you!! 💜💜

  • @pavankalyan3360
    @pavankalyan3360 3 ปีที่แล้ว +1

    Great work 🤗

  • @zakirzak1494
    @zakirzak1494 4 ปีที่แล้ว +2

    Supper stuff .... power packed 😉

  • @thecharming473
    @thecharming473 2 ปีที่แล้ว +1

    In M2 and M4 receptors shouldn't it be inhibition of sympathetic functions??

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  2 ปีที่แล้ว +1

      Yes! I made a mistake!
      I should’ve wrote: “M2 and M4 stimulation is responsible for the inhibitory effects of parasympathetic.”

    • @thecharming473
      @thecharming473 2 ปีที่แล้ว

      Yes...Thank you

  • @InertialFire312
    @InertialFire312 3 ปีที่แล้ว +3

    Thanks for making a boring topic so entertaining :))

  • @andre929
    @andre929 ปีที่แล้ว

    M2 - decease hr , decrease contractilty
    Inhibit parasymphatetic response ??

  • @marianneke61
    @marianneke61 3 ปีที่แล้ว +1

    Very helpfull thank you!!

  • @michaelsw0rd
    @michaelsw0rd 3 ปีที่แล้ว +2

    HAHA 8:15 "Why is it not named F-protein, F as in F U" so relatable towards to material being studied

  • @nitestriker9804
    @nitestriker9804 3 ปีที่แล้ว +1

    are M1 receptors in the brain ??

  • @YoyoYoyo-lc6nb
    @YoyoYoyo-lc6nb 2 ปีที่แล้ว +2

    Thanks❤

  • @nikolakulik824
    @nikolakulik824 3 ปีที่แล้ว +1

    Are afferent nerve fibres divided into PANS and SANS or it it just efferent nerves?

  • @faithchisanga7117
    @faithchisanga7117 2 ปีที่แล้ว +4

    I had fun😂🙏

  • @shams8917
    @shams8917 ปีที่แล้ว +1

    Life saver ❤️‍🔥

  • @wardelias
    @wardelias 2 ปีที่แล้ว

    if m3 is Gq coupled receptor and causes smooth muscle contraction, why does it cause relaxation of the GI sphincters instead of contraction? (though physiologically it makes sense, my question is mainly why its not through M2 or M4 but M3)

    • @shadowkokufu9178
      @shadowkokufu9178 ปีที่แล้ว

      Probably because it's not inhibitory? If it closed the sphincters then it would inbibit the GIT because there wouldn't be any movement of content.

  • @afzalpathan1156
    @afzalpathan1156 ปีที่แล้ว +1

    Wow too good 🤩🤩🤩

  • @janhavis.8360
    @janhavis.8360 4 ปีที่แล้ว +1

    sir what coffee does to your heart rate? should i take coffee if i have a heart rate in a range of 50 to 55 ?

  • @EpitomeProductionz
    @EpitomeProductionz ปีที่แล้ว

    I have long covid nervous system dysfunction. Would you at all be willing to let me pay for your thoughts regarding this condition? There's mounting studies about Nicotine improving nervous system function and relieving symptoms, I am living proof. Unfortunately my damaged brain has a hard time understanding this video, but could I pay you to go over the topic with me as well as pick your brain on what you suggest? Doctors are at a loss of what to do, at least you have vast knowledge about these nervous systems and the cholinergic nervous system.

  • @hemontikamukherjee9340
    @hemontikamukherjee9340 ปีที่แล้ว +1

    oh god, thank you so much!

  • @mutsawashe3607
    @mutsawashe3607 3 ปีที่แล้ว +1

    Beta 1 is the heart and beta 2 lungs
    Because we have 1 heart🫀 but 2 lungs🫁
    ☺️

  • @omalsadahmad-yn9vu
    @omalsadahmad-yn9vu 6 หลายเดือนก่อน +1

    Thanks

  • @bristol1946
    @bristol1946 5 หลายเดือนก่อน +1

    Amazing. 😄

  • @chemdissa
    @chemdissa 3 ปีที่แล้ว +1

    awsome, thanks

  • @alphagonist4748
    @alphagonist4748 4 ปีที่แล้ว +1

    Actions of adrenergic and anticholinergic agonists same?

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 ปีที่แล้ว

      What do you mean by “anticholinergic agonist”?

    • @alphagonist4748
      @alphagonist4748 4 ปีที่แล้ว

      @@MedicosisPerfectionalis sorry lol
      It's adrenergic agonist vs cholinergic antagonist
      Do they have same action?

  • @ThatsWhy-
    @ThatsWhy- 3 ปีที่แล้ว +1

    How does M4 receptor function ?

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  3 ปีที่แล้ว

      Gi-coupled receptor.

    • @ThatsWhy-
      @ThatsWhy- 3 ปีที่แล้ว

      @@MedicosisPerfectionalis m2 for heart receptor, but what about M4 receptor for and its function?