How Do Pain Relievers Work? - George Zaidan

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  • เผยแพร่เมื่อ 27 ธ.ค. 2024

ความคิดเห็น • 2.1K

  • @soularpower
    @soularpower 3 ปีที่แล้ว +260

    currently 4am, took one, 200mg ibuprofen for a headache. got curious and searched up on how painkillers even work. was not dissapointed, 10/10.

    • @Crown_678
      @Crown_678 ปีที่แล้ว +8

      this is 2 years later but i hope you are feeling all better

    • @fastestspring8491
      @fastestspring8491 ปีที่แล้ว +1

      Same. I jus woke from a nap. Took half of an 8 n got curious. I forgot to eat btw lolll

    • @regala_engaira4853
      @regala_engaira4853 9 หลายเดือนก่อน +3

      I was having a toothache. Also took 200mg Ibuprofen, then suddenly got curious how these things work wonder.

    • @elchapooo6668
      @elchapooo6668 9 หลายเดือนก่อน +1

      Same buddy 😂

    • @lifeman388
      @lifeman388 7 หลายเดือนก่อน +1

      Same lol😂

  • @johndavid5312
    @johndavid5312 8 ปีที่แล้ว +1712

    gets foot stuck in bear trap carries on walking what a legend

    • @LunaProtogen
      @LunaProtogen 4 ปีที่แล้ว +36

      john david Carries on to permanently damage bone tissue

    • @Peppapig-th7fr
      @Peppapig-th7fr 4 ปีที่แล้ว +10

      1 min of silence

    • @allanwells8756
      @allanwells8756 4 ปีที่แล้ว +20

      Two first names what a legend

    • @SL-pg4dh
      @SL-pg4dh 3 ปีที่แล้ว

      Rip

    • @flashback0180
      @flashback0180 3 ปีที่แล้ว +1

      That's just diabetes

  • @jw8628
    @jw8628 9 ปีที่แล้ว +8222

    Remember there's no Nociceptors in your brain. That's why you don't feel you're brain cells dying while you watch reality shows.

    • @stress.mp455
      @stress.mp455 9 ปีที่แล้ว +78

      This has been 3 weeks ago

    • @fRQpcM5uDJ
      @fRQpcM5uDJ 8 ปีที่แล้ว +36

      +Awesome EpicGamer Over 2 years ago.

    • @guitarandrums
      @guitarandrums 8 ปีที่แล้ว +67

      There are*. Your*.

    • @jw8628
      @jw8628 8 ปีที่แล้ว +18

      guitarandrums lol thanks

    • @totallynotbistol2650
      @totallynotbistol2650 8 ปีที่แล้ว +54

      Which is why doctors like doing brain surgery on awake patients

  • @willschannel_
    @willschannel_ 9 ปีที่แล้ว +1181

    I like this guy's animation.

    • @Deadlyaztec27
      @Deadlyaztec27 7 ปีที่แล้ว +13

      Über
      It makes me feel high.

    • @zac7863
      @zac7863 5 ปีที่แล้ว +19

      It reminds me of those weird drawings on Instagram, like the one where someone is throwing a baby

    • @chavalomiguel5587
      @chavalomiguel5587 4 ปีที่แล้ว +2

      George Zaidawn

    • @big.scream
      @big.scream 4 ปีที่แล้ว

      Did you survived couid ??

    • @dinosharttt
      @dinosharttt 4 ปีที่แล้ว

      Couid?

  • @terranceblakely1398
    @terranceblakely1398 9 ปีที่แล้ว +4185

    Nothing is worse than a bad toothache..

    • @xxxBradTxxx
      @xxxBradTxxx 9 ปีที่แล้ว +52

      +Sir Poet try brain surgery

    • @xxxBradTxxx
      @xxxBradTxxx 9 ปีที่แล้ว +133

      ***** I had brain surgery for epilepsy. My surgeon had to cut thru muscle and saw thru my skull to get to my brain. The regrowth of the muscles and re-fusing of the skull was the painful part.

    • @STROONZONY
      @STROONZONY 9 ปีที่แล้ว +35

      +terrance b. try having cervical spinal fusion and the pain drip comes out overnite causing you to fall out of the hospital bed and black out from the agony, which feels like someone has lodged an axe in the back of your neck. You know you have suffered maximum pain when it causes blackout. Catching on fire was another major agony, which feels like someone is smashing you with a bunch of hammers.

    • @DEADLY_HUMAN
      @DEADLY_HUMAN 8 ปีที่แล้ว +70

      get kicked on balls

    • @ayzaakrocky5325
      @ayzaakrocky5325 8 ปีที่แล้ว +19

      ever had otitis externa? ..

  • @MrShelmo
    @MrShelmo 12 ปีที่แล้ว +94

    my dad has tried to explain this to me a while back but he just went into too much detail and i never really understood it. these animations make it so much easier to comprehend. thanks!

  • @Fr4NCHILE
    @Fr4NCHILE 9 ปีที่แล้ว +1501

    Is anyone feeling pain at the moment? Like that is the reason why you found this video? I got a twisted ankle :( while practicing parkour yesterday :/

    • @Что-ю3ъ
      @Что-ю3ъ 9 ปีที่แล้ว +2

      +Francisco Carmona well yes

    • @Fr4NCHILE
      @Fr4NCHILE 9 ปีที่แล้ว +12

      +Stephen Boque dude hahaha. I twisted my ankle just a few hour ago after New Years 😭 again :/

    • @flarm
      @flarm 9 ปีที่แล้ว +1

      +Francisco Carmona what kind of shoes are u wearing? u wanna get something low to the ground... i would reccommend indoor soccer shoes

    • @MrJOKELA
      @MrJOKELA 9 ปีที่แล้ว +12

      +Francisco Carmona Yeah :( I removed my wisdom tooth and took a pain a killer, it instantly killed the pain. So I wanted to find out how painkillers work :)

    • @emummyx
      @emummyx 9 ปีที่แล้ว +6

      Tonsillitis 😞

  • @i.antagonist
    @i.antagonist ปีที่แล้ว +72

    Anyone else decided to search how pain relievers work, right after taking pain relievers?

    • @themiataboy909
      @themiataboy909 6 หลายเดือนก่อน +1

      Yup

    • @ShayRobins
      @ShayRobins 6 หลายเดือนก่อน +1

      lol yes

    • @animtres
      @animtres 5 หลายเดือนก่อน +3

      I'm currently in pain, my wisdom teeth is so swollen and sore i can't even open my mouth to talk or eat. 😢 I have even struggled opening the mouth to take the pain relievers

    • @Tavs.fāters
      @Tavs.fāters 5 หลายเดือนก่อน

      Nah, I broke my foot (navicular scaphoid). They put cast on my foot, but didn't give any pain relievers. Just wondering if it is better for body to feel pain rather to not, for healing I mean. I have high pain tolerance, it ain't so bad. accident was 8h ago. Can't find nothing

  • @disklosr
    @disklosr 10 ปีที่แล้ว +809

    0:40 that animation was so innocent and dumb I couldn't stop laughing at it

    • @Mr.Coldfire421
      @Mr.Coldfire421 9 ปีที่แล้ว +21

      disklosr You have to give thanks to your nervous system, if you don't have it you are the same with the animation you laugh at.

    • @disklosr
      @disklosr 9 ปีที่แล้ว +51

      Spongebob Squarepants Without me, my nervous system wouldn't exist. So he's the one to thank me.

    • @blue3374
      @blue3374 9 ปีที่แล้ว +6

      +disklosr I think it's more an interdependent system. Without your brain, you wouldn't be here and vice versa

    • @disklosr
      @disklosr 9 ปีที่แล้ว +3

      Lily Brown I find it amazing that the brain's purpose is to control the body and all it's organs and make sure they stay alive, but instead just gives total control to its owner and step back.

    • @blue3374
      @blue3374 9 ปีที่แล้ว +2

      disklosr Eh, I think that you aren't really the one who is constantly monitoring and messaging signals to your organs 24/7. But I'm not a doctor, so I'm not going to go around saying either of us is right or wrong. I'll just stick to 'opinions.'

  • @corekensington8733
    @corekensington8733 7 ปีที่แล้ว +101

    This animation is fantastic as it is simple enough for anyone to understand what happens regardless of age or educations level. Well done again!

  • @Deesofetch
    @Deesofetch 8 ปีที่แล้ว +144

    I have a pharmacology exam in 3 days. This was very helpful thank you !

    • @kingpaid995
      @kingpaid995 7 ปีที่แล้ว +4

      Deesofetch how did it to?

    • @packleader1215
      @packleader1215 6 ปีที่แล้ว +3

      Deesofetch
      How did it go?

    • @qeawte2243
      @qeawte2243 6 ปีที่แล้ว +12

      it's been 2 years 😂 how did it go?

    • @DarkFrostX5
      @DarkFrostX5 6 ปีที่แล้ว +19

      She failed fam.

    • @donnydont
      @donnydont 5 ปีที่แล้ว +5

      „Exam in 3 days, better start learning on TH-cam!“

  • @checkoutmypageidappreciate8555
    @checkoutmypageidappreciate8555 7 ปีที่แล้ว +1614

    who else cringed when the dude pricked his finger

  • @OMA2k
    @OMA2k 8 ปีที่แล้ว +381

    If pain is meant as a warning system to protect ourselves and so we take care of the problems in our body, then how come women suffer pain (sometimes even great pain) when performing a perfectly normal bodily function such as menstruation? What kind of "warning" is that?

    • @FRIEDYOGURT-s4c
      @FRIEDYOGURT-s4c 8 ปีที่แล้ว +11

      Yeah exactly

    • @happydays6777
      @happydays6777 8 ปีที่แล้ว +15

      It just means they have cramps

    • @darksidecola4529
      @darksidecola4529 7 ปีที่แล้ว +53

      same reason getting kicked in the balls hurts

    • @Deadlyaztec27
      @Deadlyaztec27 7 ปีที่แล้ว

      wolf pack winter
      It's precisely the same reason.

    • @Kabeliel
      @Kabeliel 7 ปีที่แล้ว +13

      Good point. I Think the body has no conscious by itself. Every part of your body is dependable from the others and in this case menstruation is a special story of how body and cells work.

  • @KaydenF901
    @KaydenF901 7 ปีที่แล้ว +1067

    Nature made pain to tell Man: "Hey, don't do that!"
    Man made painkillers to tell Nature: "Oh, believe me, I CAN do that."

    • @tracerhax
      @tracerhax 4 ปีที่แล้ว +8

      *Underrated comment**

    • @johnstevens1020
      @johnstevens1020 4 ปีที่แล้ว +2

      LMAO

    • @gregoryfenn1462
      @gregoryfenn1462 4 ปีที่แล้ว +43

      To be fair, we only use mild painkillers like off-the-shelf paracetamol to stop pain that we can’t help, like headaches or back pain or period pain. It isn’t about letting us actively try to harm ourselves and not suffer for it. The damage has already been done in the past: we’re just minimising they punishment for it.

    • @juveriafatima4678
      @juveriafatima4678 3 ปีที่แล้ว +2

      who's in loss..?

    • @cas0276
      @cas0276 3 ปีที่แล้ว +6

      A lot of people suffer from chronic pains so even when they know exactly what's wrong because of a doctor telling them the pain will almost never go away and there is nothing they can do to help it
      Most people who take hard painkillers are people who suffer from chronic disease or have hurt a part of there body really badly and can only sit and wait for the pain to get better

  • @blaizeafyah4293
    @blaizeafyah4293 9 ปีที่แล้ว +30

    Really appreciated this, all knowledge should be this simple and comprehensive

  • @sawifythis
    @sawifythis 12 ปีที่แล้ว +108

    I learned more in 4 minutes than I did in 3 weeks of biology.

    • @issavibez394
      @issavibez394 2 ปีที่แล้ว

      School is scam

    • @sotinsim7113
      @sotinsim7113 ปีที่แล้ว +1

      Facts

    • @Pluto700.-9
      @Pluto700.-9 ปีที่แล้ว +3

      @@sotinsim7113y did u reply 10 years later 😂

    • @Sketchy.editz123
      @Sketchy.editz123 8 หลายเดือนก่อน

      ⁠​⁠​⁠@Centralcee170why did you reply 11 years later😂

  • @RinaNewhouse
    @RinaNewhouse 7 ปีที่แล้ว +107

    This is great! I am making a brochure about ibuprofen for my chemistry class, and I had to write one column on its mechanism. At first, I was reading articles that just made me want to give up. Then, I realized that Ted-Ed is here for a reason, so I clicked on this video!!!! This helped me SO much better than the near-impossible-to-comprehend articles which explain the exact same concept! I'm nearly done with my brochure and I feel pretty proud of it!!! Let's see if my grade thinks the same... 😉😉😉

  • @MrTrees
    @MrTrees 5 ปีที่แล้ว +27

    Fell on my shoulder and haven’t been able to lift it cause it hurts so much.
    Had some ibuprofen and it worked so much it interested me. Here I am.
    Now I know how pain works and how these magic science pills work.
    So cool man...

  • @PatrickSingsASong
    @PatrickSingsASong 4 หลายเดือนก่อน

    I'm having ongoing complex pain issues, and Ive gotta say, this video really hit the spot. Thank you. Nice one.

  • @MrCapi55
    @MrCapi55 7 ปีที่แล้ว +9

    At last, I know why do I sleep very well when having painkillers .Thank you ,George Zaidand.

  • @aryaparekh1854
    @aryaparekh1854 2 ปีที่แล้ว +7

    Pain protects you from the world around you, and from yourself. Why did it hit me emotionally 🙂

  • @SheCriesRed
    @SheCriesRed 5 ปีที่แล้ว +8

    This helped me understand my condition of fibromyalgia a little better. Of how it works more or less.

  • @imhellag
    @imhellag 4 ปีที่แล้ว +15

    that brain driving the car is one of the best things ive seen all day

  • @maaroufchebbo2691
    @maaroufchebbo2691 7 ปีที่แล้ว +1

    Im a sever hemophiliac so km in alot of pain almost all the time but i have found out that music and talking with peanut while just keeping on a good mood and attitude eliminates the pain for the most part its really interesting how the human body works

    • @NothingTheGreat
      @NothingTheGreat 7 หลายเดือนก่อน

      Talking with peanut?

  • @erikbedard713
    @erikbedard713 4 ปีที่แล้ว +41

    I'm a grown man but when I stub my toe on a wall corner I curl up in the fetal position for 5 mins due to the pain.

  • @M.Melkonyan
    @M.Melkonyan 5 ปีที่แล้ว +3

    Animations are perfect, huge thanks from Armenia

  • @prakashminj8455
    @prakashminj8455 8 ปีที่แล้ว +376

    No pain, no gain.

  • @justjuli3t
    @justjuli3t 2 ปีที่แล้ว +11

    Can you explain why Ibuprofen works a lot better for a toothache than a stronger painkiller like oxycodone? I have a throbbing toothache and I regularly take oxycodone for another medical problem so I took 1 for my toothache and it did nothing so then I had 2 ibuprofen and the pain went away 20mins later.

    • @babypluto08
      @babypluto08 2 ปีที่แล้ว +1

      Thanks for helping me. I got 5 teeth extracted and just downed 2 ibuprofen instead of the narcotics and I feel sooooo much better

    • @Hellopeople4
      @Hellopeople4 2 ปีที่แล้ว +1

      For Toothache best medicine is Clove oil , get from Indian grocerry store it cost you around $3 and dip qtips into it and hold that qtips affected teeth . You will see how instantly help . For best result 3 times btush your teeth a day with different toothpaste mean take one Colgate other Ayurvedic ( Dabur toothpaste ) and Sensodine . Then use clove oil . You will be amazed

  • @jaquelinecorvera5269
    @jaquelinecorvera5269 9 ปีที่แล้ว +12

    This is such an entertaining and educative video. I effin love it.

    • @Zorak9595
      @Zorak9595 9 ปีที่แล้ว +5

      It effin loves you too

    • @chimneyshouse9701
      @chimneyshouse9701 9 ปีที่แล้ว

      loxxxèxbxxushsbshhxhxhhxhnnnznbzbbzbsbsbbsbsbsbbsbsbsbsbbsbsnsnsnn a

  • @SuperFa6ooma
    @SuperFa6ooma 11 ปีที่แล้ว +2

    It's great how a 4 minutes video summarised a lesson of 60 minutes.. Thank you =).

  • @lozzylols
    @lozzylols 5 ปีที่แล้ว +22

    I find if I go into a form of meditation and concentrate on the pain and the area it is in, I can reduce the pain. It's hard to explain but I try to imagine the pain, like the images in this video, and imagine calming them down and letting them float away, and it does seem to ease the pain yo some degree! Also I am often in pain as I have Fibromyalgia!

    • @jaylyn1471
      @jaylyn1471 3 ปีที่แล้ว +1

      You can one hundred percent control pain if you know it's all just in your head.

    • @Rick_Cleland
      @Rick_Cleland 2 ปีที่แล้ว

      @@jaylyn1471 Not if one of your arms is chopped off.

  • @liamwelsh5565
    @liamwelsh5565 4 ปีที่แล้ว +8

    One thing that always was a mystery to me is when you have a minor injury such as a cut or scrape, you don't feel it until you consciously know you did it or physically looked at it. It has briefly covered at the end but not explained. Do we know why this happens?

    • @AZ-il8uc
      @AZ-il8uc 2 ปีที่แล้ว +1

      I'm no scientist. But the brain is a very powerful thing. Ignorance is bliss. And if you don't know, you usually carry on in the same perceived state you were in pre injury. Granted it's a superficial injury. Kinda like with placebo effects. You tell someone it's going to work, they expect it to, so now their brain is geared towards "this thing is doing what they said it'll do"

  • @perplexedmoth
    @perplexedmoth 10 ปีที่แล้ว +51

    So if aspirin permanently blocks COX-n, like for how long?

    • @michellewarner2634
      @michellewarner2634 10 ปีที่แล้ว +6

      5 - 7 days

    • @AxeAR
      @AxeAR 5 ปีที่แล้ว +7

      @@michellewarner2634 Well, not so _permanently_ after all

    • @dirtywash4890
      @dirtywash4890 5 ปีที่แล้ว +21

      If you take enough tylenol you wont feel pain...ever again

    • @amydocherty7317
      @amydocherty7317 5 ปีที่แล้ว +7

      Boy Graffity I’m not certain AT ALL and am taking a wild guess right now but I’m assuming the Cox-n enzymes are replenished

    • @cutureanantonio6723
      @cutureanantonio6723 5 ปีที่แล้ว +2

      Ibuprofen is better

  • @ranpo677
    @ranpo677 11 ปีที่แล้ว +2

    Thanks for explaining in plain english and with nice visuals.

  • @cosmicanu
    @cosmicanu 2 ปีที่แล้ว +1

    Placed crown on my tooth ..next day chopped off half of my nail by a sickle and deep cut in finger. Took pain killer and was curious to know how they work.
    This was such an amazing video.

  • @allangozun870
    @allangozun870 7 ปีที่แล้ว +13

    I love this animation! very simple and easy to understand. Good job!

  • @TheBolinhadigudi
    @TheBolinhadigudi 8 ปีที่แล้ว +19

    "All pain comes from the desire of not wanting to feel it" Renato Russo

  • @maheshdarisa
    @maheshdarisa 4 ปีที่แล้ว +3

    I was looking for 3:21
    Thanks dude, I know this but just need a confirmation

    • @jesusssheep
      @jesusssheep 4 ปีที่แล้ว

      Does it work to die without feeling pain

  • @xiqikxx8967
    @xiqikxx8967 7 ปีที่แล้ว +2

    I take Ibuprofen 3 times a day and it really always works to block away my painful synovial osteochondromatosis

  • @emilynaples127
    @emilynaples127 4 หลายเดือนก่อน

    This was so super helpful, clear, and well explained. Thank you for making!

  • @branhoff
    @branhoff 5 ปีที่แล้ว +10

    Is there some advantage to ibuprofen’s approach of not permanently deactivating the enzyme as opposed to aspirin?

    • @lozzylols
      @lozzylols 5 ปีที่แล้ว

      I was curious about this as a aspirin wears off too doesn't it!

    • @theheini5329
      @theheini5329 5 ปีที่แล้ว +1

      @@lozzylols I think that just means the aspirin stays in the system and blocks COX1 and COX2 for a longer time than it does in Ibuprofen.

  • @diegobelaunde4965
    @diegobelaunde4965 5 ปีที่แล้ว +7

    Here because I went to a metal concert last night and I head banged my heart out, so now my neck is sore lol
    No regrets tho🤘🏽🤘🏽

  • @zacharygrossman8316
    @zacharygrossman8316 4 ปีที่แล้ว +8

    Who is watching this after taking a pain reliver?

  • @GangstaCreeper
    @GangstaCreeper 3 ปีที่แล้ว

    I just had an essay assignment on this subject due a few hours ago today
    This would've been so useful at that time

  • @A1sinceday1-88
    @A1sinceday1-88 5 ปีที่แล้ว

    This help me calm down. I have a tooth ache/awaiting surgery. This was mentally relaxing cause I know the drugs are coming.

  • @gringobingo471
    @gringobingo471 6 ปีที่แล้ว +13

    "Through pain i gain strenght"

  • @Lieveo
    @Lieveo 10 ปีที่แล้ว +16

    I think this Talk could have had quite a bit more information

  • @fishsticks6969
    @fishsticks6969 8 ปีที่แล้ว +49

    how does Paracetamol work ? what's the difference between Aspirin and Paracetamol

    • @anotsosexysaxman5914
      @anotsosexysaxman5914 8 ปีที่แล้ว +15

      believe it or not. we don't know for sure. I'm doing an assignment on ibuprofen and paracetamol and I was shocked when I heard it

    • @emdadahmed5592
      @emdadahmed5592 8 ปีที่แล้ว +19

      Paracetamol is an antipyretic(fever reducer) & analgesic(pain reliever).
      However, aspirin is an NSAID aka Non-Steroidal Anti-Inflammatory Drug. It has 3 uses. In addition to being an antipyretic and analgesic, it also reduces swelling(inflammation). This anti-inflammatory property isn't possessed by paracetamol

    • @fishsticks6969
      @fishsticks6969 8 ปีที่แล้ว +11

      After some research i found out that Paracetamol slows down the generation of Prostaglandins only in the brain, while Aspirin stops the generation of Prostaglandins throughout the body, this can cause other body organs to stop functioning properly.

    • @abhipatel8890
      @abhipatel8890 8 ปีที่แล้ว +2

      YO I AM DOING A ASSIGMENT ON IT TOO. Brother hook me up with some information. If you have any reserach can you email me it. I would love it if you could help me out.
      email is: Abhipatel7122000@gmail.com

    • @anotsosexysaxman5914
      @anotsosexysaxman5914 8 ปีที่แล้ว

      Emdad Ahmed that's a theory
      not actually accepted tho

  • @Ravengal101
    @Ravengal101 5 ปีที่แล้ว

    I wish this video offered more on neuropathic pain.

  • @kimhoffman2495
    @kimhoffman2495 8 ปีที่แล้ว +1

    When I had appendicitis in my youth all the nurses told me and my mother I had an incredible pain tolerance. I couldn't stand up straight, hunched over but I still basically said "meh". I once was told that most adults said the pain was 11 or 12 on a scale going up to 10 while the highest score I gave them was a 5. Though I think they were just trying to make me feel better. It was more painful after surgery really and I was annoyed on how slow I had to take everything. Walking, getting out of bed, exercising down the hall.
    I once had met my doctor out on my hourly walk in the hall and I just wanted to get back to my room as quickly as possible so he could do the check up but my mother and the doctor kept telling me to slow down. I was about 14, so I wanted to rebel, and be left alone. My two days in the hospital were the slowest, most boring days of my life. I thought I had been there over a week how bored I was.

  • @julianab1388
    @julianab1388 9 ปีที่แล้ว +348

    Who else cringed at about 1:23?

  • @laurenfierro7863
    @laurenfierro7863 4 ปีที่แล้ว +4

    BRUV I just got that time of month pain on a whole other level

  • @ibelieveingaming3562
    @ibelieveingaming3562 9 ปีที่แล้ว +12

    If we can understand pain, we can build artificial nociceptors which receive input from a simulated body, essentially emulating nervous stimulation in the simulated world.

    • @nirvana10393
      @nirvana10393 3 ปีที่แล้ว +2

      What a sad creation that would be.

  • @shreyas9204
    @shreyas9204 7 ปีที่แล้ว +1

    At 3:33 what do you mean when you say 'and they go to painful areas just the same as normal ones' ? What does 'normal ones' mean?

    • @thasonicfan2000
      @thasonicfan2000 6 ปีที่แล้ว

      He's talking about the areas of the body that aren't feeling pain. That's what he means when he says "normal".

  • @akio-n5o
    @akio-n5o 2 ปีที่แล้ว +1

    tooth pain and cysts, boils, lumps are the most painful for me. They are not huge but packs a punch.

  • @wsigned1323
    @wsigned1323 9 ปีที่แล้ว +142

    That guy's going to keep walking with that bear trap clamped to his leg and I don't think there's anything we can do about it!

    • @269kd
      @269kd 3 ปีที่แล้ว +1

      Serves him right

  • @srayanguhathakurta4488
    @srayanguhathakurta4488 2 ปีที่แล้ว +9

    As a wise man once said,
    "Feel PAIN, Accept PAIN and Know PAIN...Those who do not know PAIN will never understand true peace." Guess he had a point.

    • @ingredientIOS
      @ingredientIOS ปีที่แล้ว

      We more
      She blesses
      She pet my beard
      Malubululllll

    • @nibo_am1315
      @nibo_am1315 ปีที่แล้ว

      no thanks *takes pain killer*

    • @urveshchilhate7552
      @urveshchilhate7552 ปีที่แล้ว

      By Pain

    • @WildlifeSampler
      @WildlifeSampler ปีที่แล้ว

      PEINNN!! but no thanks, I would stick to painkillers

  • @fluffypurplepop4629
    @fluffypurplepop4629 3 ปีที่แล้ว +4

    Thanks for this video I was wondering how the medication knows where the pain is so it can fix it. Turns out it doesn’t and goes all around the body which is interesting.

  • @Madinavibes6979
    @Madinavibes6979 3 ปีที่แล้ว

    ALLAH PAK SAB KO SHAFA ATA FARMYEE♥️♥️♥️

  • @mr.greengold8236
    @mr.greengold8236 3 ปีที่แล้ว +1

    But the prostoglandins have a huge protective function is guarding the stomach mucosa. That's why so many long time users of these amd NSAIDs have an increased risk of stomach ulcers.

  • @morphin4200
    @morphin4200 10 ปีที่แล้ว +6

    I'm watching this sort of videos just for learning other languages using subtitles in the settings. Try this next time you're bored.

    • @dds3524
      @dds3524 10 ปีที่แล้ว

      I never get bored.

    • @codyhitchcock3443
      @codyhitchcock3443 9 ปีที่แล้ว +1

      Wouldn't you choose a video with simpler language?

    • @Sohamsta
      @Sohamsta 4 ปีที่แล้ว

      I agree that this is very helpful for vocab

  • @alenzhang4854
    @alenzhang4854 4 ปีที่แล้ว +22

    0:40 apparently that person is also deaf

  • @packleader1215
    @packleader1215 6 ปีที่แล้ว +3

    Anybody else here pacing before bed, waiting for it to kick in?

  • @katharinayay
    @katharinayay 5 ปีที่แล้ว

    Got a root canal 6 months ago and it was done by a pretty shatty dentist. So, my tooth cracked vertically and i’m literally dying of pain right now so i decided to educate myself a little while waiting for the painkiller to kick in

  • @Unitedairies
    @Unitedairies 4 ปีที่แล้ว +1

    So beautiful animation....I like your teaching.... love from india ❤️❤️❤️❤️❤️❤️

  • @ScornMuffins
    @ScornMuffins 10 ปีที่แล้ว +10

    As useful as pain is it would be nice to be able to stop it on cue in the event of a false alarm or such a time when damage cannot be prevented. Like how you can hold your breath up to a point but eventually you'll start breathing automatically again.

    • @542Damian
      @542Damian 10 ปีที่แล้ว

      You can, it's called anger. If it's strong enought it will allow you to ignore pain.

    • @Wrongrealities
      @Wrongrealities 10 ปีที่แล้ว

      Damian Wójcik A person can overcome pain using any emotion, or concentrating on a peaceful place, but the adrenaline we produce when we are in danger, or for some reason need to react (it might be anger, but more often it is fear) is the best way to numb pain naturally... It's either that or PCP, but PCP is not natural and not good.

    • @joseph2835
      @joseph2835 10 ปีที่แล้ว +1

      Its called adrenaline

  • @davidndiulor8428
    @davidndiulor8428 9 ปีที่แล้ว +57

    If you are normal... Aw shit

  • @fabiocerqueira5097
    @fabiocerqueira5097 4 ปีที่แล้ว +3

    Adorei a explicação!

  • @TheBlaze4000
    @TheBlaze4000 11 ปีที่แล้ว

    i love videos like this, it makes me realize our human bodies are so awsome!!!

  • @duongtran9655
    @duongtran9655 3 ปีที่แล้ว +2

    Thanks so much for sharing ! Have a good night , good health and safety holidays ! 🤙

  • @ayesp6188
    @ayesp6188 5 ปีที่แล้ว +5

    This reminds me of when I was like 10 and I crushed a bunch of chalky ibuprofen, lined it up with the home phone and snorted it with a straw.

    • @kristve6798
      @kristve6798 4 ปีที่แล้ว

      excuse me, *what*

  • @kyo803
    @kyo803 4 ปีที่แล้ว +2

    When he started pushing his finger to the needle i screamed so loud...

  • @randomuserjusthere4930
    @randomuserjusthere4930 5 ปีที่แล้ว +12

    “Doktor, turn off my pain inhibitors.”

  • @mtktkt3773
    @mtktkt3773 2 ปีที่แล้ว

    thank u so much for this video. the animation was so easy to understand. very well done!

  • @emuriddle9364
    @emuriddle9364 3 ปีที่แล้ว +2

    I have a relative who isn't able to feel pain.
    There really is a benefit to having pain receptors.
    He had a bad cut, and didn't notice it until someone saw it a few hours later.

    • @spicymeatballs2thespicening
      @spicymeatballs2thespicening 2 ปีที่แล้ว +2

      Definitely, although the body tends to make pain a bigger issue than it has to be. Once you know what the problem is there's no reason to continue suffering so much

  • @surya8891
    @surya8891 8 ปีที่แล้ว +5

    can anyone explain me how placebo effect helps us relieve from pain ?

    • @maltoskater66
      @maltoskater66 8 ปีที่แล้ว +2

      Basically your brain tricks itself into thinking there is no more pain

    • @Paulosilva-hk8bo
      @Paulosilva-hk8bo 8 ปีที่แล้ว

      +maltoskater66 Actually,placebos are useless medicine.They don't relieve you from pain or diseases.Some shops sell those so they can get money and well,frustrated clients.So be careful out there.

    • @majalnvik9068
      @majalnvik9068 6 ปีที่แล้ว +3

      Actually, Paulo silva, not true! Placebo works as a charm. That's the definition of placebo. It works even though it has no effect. Maltoskater66 is right, it tricks your brain. If you believe a medicine will work, it actually does a lot of times.When it comes to pain placebos are great, because the brain can modulate pain signals so that you don't feel them. The big problem with placebos though, is that if you know it's a placebo you won't believe in it - and therefor it won't work.

    • @ericyahav1
      @ericyahav1 6 ปีที่แล้ว

      surya u are gullible, that's how

  • @frempley1
    @frempley1 6 ปีที่แล้ว +5

    Why is this video age restricted

    • @ethanstyles8730
      @ethanstyles8730 5 ปีที่แล้ว

      Cox-1 and Cox-2 maybe, TH-cam’s algorithmic workings are rather strange

  • @eventplanner461
    @eventplanner461 4 ปีที่แล้ว +3

    Okay, now tell me why I felt pain when I watched the animation push their finger into the needle.

  • @thedancingparamedic
    @thedancingparamedic 4 ปีที่แล้ว

    me and my fractured foot thoroughly enjoyed this

  • @fajarsoniawan8779
    @fajarsoniawan8779 6 ปีที่แล้ว +1

    How can I say thank to you guys? It is too great for me.. Thank you so much 🙏

  • @shoaibakhtar4389
    @shoaibakhtar4389 5 ปีที่แล้ว +8

    1:37 nerve receptors telling body stops doing whatever you doing. 😂

  • @harikishore2514
    @harikishore2514 5 ปีที่แล้ว +28

    Cox entered the chat.
    I: lost.

  • @PotterHead1596
    @PotterHead1596 8 ปีที่แล้ว +3

    So which one is better at relieving pain, aspirin or ibuprofen? And which one is better for your body than the other?

    • @daivavens9873
      @daivavens9873 8 ปีที่แล้ว

      ibuprofen is more used and recomended now and it is more safe

    • @peggychai2714
      @peggychai2714 8 ปีที่แล้ว +1

      +sarah kabobs Both of them pretty much work the same way being aspirin or ibuprofen. It's just that aspirin are not suitable for people who are under 16 years old (prone to Reyes Syndrome) or NSAIDS are not suitable for people who have history of gastric ulceration, asthma and etc.

    • @fredrikkarner4115
      @fredrikkarner4115 8 ปีที่แล้ว

      +Dai Ven safer

    • @revengeofachild
      @revengeofachild 8 ปีที่แล้ว

      pretty much the same, they both have side effects to gastrointestinal tract. so if you have peptic ulcer you shouldn't use NSAID or use selective NSAID like celecoxib

    • @Jimmybucketzz
      @Jimmybucketzz 7 ปีที่แล้ว +1

      Ibuprofen gives horrible nightmares I kicked the wall while asleep against the wall it Hurst so much I had to deal with that pain. garbageprufen

  • @MountainLion96
    @MountainLion96 ปีที่แล้ว +1

    Beautiful animation, very interesting and informative video

  • @Bluesteel157
    @Bluesteel157 11 หลายเดือนก่อน

    Very nice video. Can we have a video like this to show the harmful side effects of painkillers?

  • @annari746
    @annari746 3 ปีที่แล้ว +4

    Here after I got my tooth extraction 😭😭😭

  • @Jiftoo
    @Jiftoo 4 ปีที่แล้ว +6

    1:04 I can't stop laughing

    • @rodr439iguez
      @rodr439iguez 4 ปีที่แล้ว

      👀

    • @masterrucu
      @masterrucu 3 หลายเดือนก่อน +1

      🤷?💩🤡,🙄

  • @someasianweeb1660
    @someasianweeb1660 8 ปีที่แล้ว +116

    Him: let's say your at the beach and you get sand in your eyes, how do you know it's there?
    Me: because you told us there was sand in out eyes.

  • @MostPowerfulPMofIndia
    @MostPowerfulPMofIndia 5 ปีที่แล้ว +1

    Wow such a deep research

  • @mayam3857
    @mayam3857 7 ปีที่แล้ว +1

    How do the cells get damaged in the first place? And do they mean nerve cells or other kinds of cells? (1:48)

  • @LeserDrac333
    @LeserDrac333 5 ปีที่แล้ว +7

    Pain reliever for broken heart?

  • @lynetteleprince6738
    @lynetteleprince6738 5 ปีที่แล้ว +3

    who’s currently watching on ibuprofen?

    • @simondavis6620
      @simondavis6620 5 ปีที่แล้ว

      lynette le prince That’s why I searched this, I just took some Advil.

  • @Kamaljama
    @Kamaljama 2 ปีที่แล้ว +2

    we have watched 4 minutes Ad without noticing

  • @sayo1968
    @sayo1968 9 ปีที่แล้ว

    words of thank are not even enough to thank you !!

  • @BatBrakesBones
    @BatBrakesBones 4 ปีที่แล้ว

    I have this intense muscle soreness. Took ibuprofen liquid gels and it's been relieved dramatically. I could barely walk. Don't wanna be on ibuprofen for months on end, though.

  • @bucky937
    @bucky937 4 ปีที่แล้ว +4

    "There are people who can't feel pain"
    Berserk fans and Metal Gear Rising fans: I see this as an absolute win.

  • @kaaarunya_
    @kaaarunya_ 4 ปีที่แล้ว +2

    A migraineur (me) watching this video trying to understand why painkillers don't kill the pain. 😶✨🧠🔨

  • @MontherAlcharbaji-mf2xr
    @MontherAlcharbaji-mf2xr ปีที่แล้ว +3

    Like is your watching this and have pain

  • @WILL12313213
    @WILL12313213 2 ปีที่แล้ว

    How does Acetaminophen (Tylenol) fit into this? Does it also work in the active sight of the enzymes or does use another method?

  • @DrNiteshRaj
    @DrNiteshRaj 4 ปีที่แล้ว

    Superb explanation model