Tracking Plasma Taurine: 13-Test Analysis

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[@peterz53]

Michael, the major 2023 paper by Yadav indicated that exercise will increase plasma taurine, or its metabolites. But by how much and how long is it sustained is not clear. I have a good level (102 microM last iollo test) but I am 70, exercise, eat well and have supplemented long term (12 years) with 500 mg/d taurine due to its supposed vascular benefits and because I am mostly plant based. Did not supplement on morning of blood draw.

[@conqueragingordietrying123]

Thanks @peterz53-the only caveat that I'd add is that exercise *can* increase plasma taurine, but that may not be true for everyone. Similarly, exercise and CR increase NAD, but mine are chronically low, ~25uM
But, the key is testing, and good job on your plasma taurine levels, especially when considering your older chronological age!

[@stx7389]

​@@conqueragingordietrying123 why would you not supplement taurine ar least like 2-3 times a week and 250mg lets say?

[@edvedder7835]

Thanks for the video Michael. I find that Taurine helps prevent me from waking up to pee overnight.

[@TheReminderChannnel]

So excited to watch this! 😬🙊🙄
Have had some very beneficial effects from taking taurine everyday!
Thank you as always Michael! 💪 🙏

[@barrie888]

fascinating stuff . taurine is in my workout mix

[@andrewtaylor9799]

Highly informative, thanks. Can you quantify your Taurine intake from diet? I've been supplementing with 3 g of Taurine in the morning and another 3 g in the afternoon.

[@conqueragingordietrying123]

Thanks @andrewtaylor9799. Unfortunately, Cronometer doesn't include taurine. A rough estimate could be via protein intake, but that isn't currently correlated with taurine...

[@Watchingyoutube-x6o]

Thank you for this information.

[@blahizake]

The majority of animal food products in U.S. will be drained of fluids containing taurine. Even then, most of our cooking methods will further drain the remaining taurine, unless you’re drinking all of the juices at the bottom of the crockpot.
Highest:
- Beef cheeks, heart, liver, and tongue
- Clams, mussels, scallops, and oysters
For anyone curious, scallops, oysters, clams, and mussels are particularly high in DHA, taurine, glycine, and iodine.

[@conqueragingordietrying123]

Protein intake doesn't necessarily raise plasma taurine, detailed in the video.

[@BH-obh]

Interesting that protein (methionine in dem sardines)doesn't corrolate. Wonder how it correlates with B vitamins and homocysteine? Saying more than I know.

[@conqueragingordietrying123]

Yep on no correlation with protein intake, which highlights measuring plasma levels, rather than assuming intake will increase plasma levels...
After 14 tests, B vitamins aren't significantly correlated, and I'll check for correlations with homocysteine

[@auricauric8150]

The negative correlation seems to be supported by current taurine studies in humans/animals where it reverses signs of metabolic disease whilst fructose (and excess carbs) cause/worsen metabolic disease. Would be interesting to see if taurine correlates with your meat intake (very limited in your case) or exercise which i believe also correlates with taurine levels. What i find most shocking is that how low doses seem to have an effect (and unrefined as well, since you're mostly whole food diet). It'd be interesting how taurine levels get tanked with HFCS processed garbage most people eat.

[@conqueragingordietrying123]

Taurine is not significantly correlated with sardine or dairy intake (which are consumed daily) through 14 tests
I haven't looked at correlations with the average daily HR, as an index of daily physical activity/stress, but that could be interesting!

[@stx7389]

Carbs DO NOT worsen metabolic disease! Vegans that eat 55% + carbs have by far lowest rates of diabetes!

[@chrisgiles5653]

Taurine supplementation at 1g/day seems to interfere with my sleep, not improve it as some other people say. Anyone else affected in this way?

[@ChessMasterNate]

That Fructose taurine graph did not look very compelling. Take away one data point and it looks totally random.

[@conqueragingordietrying123]

I mentioned that in the video-while 1 data point could be driving the correlation, alternatively, it's preliminary data for what could be a real effect. The only way to know is by filling in the gap (fructose in the 50-50g/d range), which is on the to-do list.

[@ChessMasterNate]

@@conqueragingordietrying123 I don't know I how I could have missed that.

[@Nando_lifts2021]

I wonder if as our bodies age we don't need as much taurine or other molecules to run optimally. Simply because we aren't capable of running optimally( like in our teens and 20's)

[@paulcohen6727]

If you get more fructose from eating plant food. and so, getting more of your calories from plants, which have no taurine in them, then of course, you'll be eating fewer calories from animal food which do have taurine in them. So that would explain the drop in plasma taurine, simply because you're getting less of it in your diet.

[@conqueragingordietrying123]

Interesting hypothesis-if that were true, animal products (sardines, yogurt, eggs) would be positively correlated with taurine, but they're currently not...

[@Funkypitspaul]

Thanks for all the great content!!! I was wondering if the sulforaphane video follow up is out or coming soon? In the original video were the sulforaphane concentrations of broc sprouts extracted from dehydrated plant material? It said dry weight and I think that means dehydrated . I also just left a comment on the original video.

[@conqueragingordietrying123]

Thanks @Funkypitspaul!
I had to stop the sulforaphane experiment-I'm not sure if it was a bad batch of seeds or infected sprouting jars, but they developed mold, and ruined eating broccoli sprouts.
I'm still eating a ton of collards (450g/d), which have sulforaphane, albeit not as much as broccoli sprouts.

[@SeminarioMAE]

@@conqueragingordietrying123 Did you try disinfecting the seeds in food grade peroxide before sprouting?

[@conqueragingordietrying123]

@@SeminarioMAE Unfortunately not. I don't do that for alfalfa sprouts...

[@notaras1985]

How to save cooked arteries and microcirculation that were damaged by COVID?😢

[@conqueragingordietrying123]

Nattokinase could be an option: pmc.ncbi.nlm.nih.gov/articles/PMC9458005/

[@notaras1985]

@conqueragingordietrying123 thanks. It exists in Japanese Natto fermented soybean food right

[@conqueragingordietrying123]

@ yep

[@paulcohen6727]

So, since taurine prevents depression, you should know if you're taurine levels are adequate simply because you are not depressed very often.