Taurine: The Nutrient of Youth [Science Explained]
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[1] doi:10.1126/science.abn9257
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#antiaging #agingbackwards #taurine
![These Molecules Reversed Aging by... YEARS! [TRIIM Study Explained - Study 216]](http://i.ytimg.com/vi/rVoxfABoHh4/mqdefault.jpg)
3 Things:
1. On a quick search (I haven’t looked into this deeply), taurine seems to reduce or attenuate increases in cholesterol lipoproteins according to a meta-analysis (DOI: 10.1016/j.ejphar.2020.173533). So, as I suspected, it isn’t much of a worry (I’ll need to confirm this) - yet the association with increased blood levels is still a mystery - why do you think it might be the case?
Let’s take some guesses!
2. And, apparently I see 'orange' as 'red', yet I'm not color blind..
3. @6:43 - that should read 'SASP', not 'SAPS'.
inb4 "cholesterol isn't a worry..."
That was definitely red. Also, cholesterol isn't a... oh wait, nvm
I think I’ll wait a bit for more studies. I was excited about GlyNAC until I ran across a study on HCC (Hepatocellular Carcinoma) and NAC. That was scary. I operate on cancer patients daily so my view of the world is that everyone has cancer. I need to dig into this a little deeper.
@@pacmanfl HCC? have Physionic look into it.
I suspect that it's not the taurine causing blood lipid issues rather, dietary patterns that lead to high blood levels of taurine also tend to negatively affect lipids (ie. high meat diets). Shouldn't be an issue with taurine supplementation if that is the case.
I worked in health care for 33 years. The first 13 of those years was in a seniors' nursing home. I have seen residents who lived to be well into their 90's but were wheelchair bound since they were 70. Longevity IS NOT the preferred outcome (unless you are scared to die I suppose), but rather quality of life. Living to be 85 years old while still being active, independent, mobile, mostly free of pain and living and loving those you care about is the goal. When I look at these sorts of studies, I am interested in longevity potential but I key in on those aspects that imply a better quality of life, i.e. hirer bone density from Taurine supplementation.
Exactly.
The US promotes longevity because it enables CONSUMERS to live longer and spend and consume longer, especially if they are CONSUMERS of health care, which is about 1/6th of our economy, 18%. A good quality of life in old age is not of concern and is to be discouraged, from that standpoint.
1
www.ncbi.nlm.nih.gov/pmc/articles/PMC4712861/ That why you have to not do what doctors say because they are killing us and figure it out for yourselves.
I've been around this particular block MANY times. I took care of both my parents, as well as my step mother...at separate times, with accumulated 30 years of caregiving. I saw a total amount of years seeing inside nursing homes for 7 years. People DO NOT do well in nursing homes. That in itself tends to age people and certainly does not offer optimal quality of life. And quite frankly, a "wheelchair" does not deter from the quality of life, for one who has values in the right place. But if you wanna go, by all means, short change yourself.
Highlights
💡 Taurine supplementation increased lifespan by 10-12% in mice.
💡 Taurine supplementation reduced body fat, improved muscle strength, and blood sugar levels.
💡 Taurine showed potential in reducing senescent cells and increasing stem cells.
💡 The study suggests that taurine can be beneficial later in life, even if not taken in the earliest stages.
💡 While there are some potential negatives associated with taurine, further research is needed to fully understand its effects in humans.
❤😊people 😮
supplemention, thats where u go wrong bud, its in animal meat and natural
@@RapatipatooO that's true. I consider myself an older person, with 3 grandchildren and I love to eat meat and eggs, butter,... What I discovered years ago is that older people eat less and less. I'm not ready to go to a care home yet but I visited my mum and others and I could see for myself that although the meals were good quality, older people don't eat enough meat and food of animal origine. Not a fan of supplements because I know it's big business, nothing more than that. We all have to go back to nature.
From my understanding most of the negatives that have shown in research aren't consistent and no one can really figure them out yet...
Thank you
Very informative video. I am a 64 year old male. I started taking a Taurine 500mg supplement about 3 months ago. I have been getting better sleep. I have also noticed more energy. My sleep is more restful and deep. My energy has slightly increased. I plan to continue to take Taurine.
I now take 10g in the evening. Sleeping amazingly. Nmn at dawn, taurine at dusk.
Hi senior folks,
Can u help me to know in what age around we stop getting night time erections and stop feeling sexual desire?
I am in my 20s but unfortunately i am bad in my family background i dont have mom dad any uncle any grand dad nothing. So noone senior here i can speak to
@@henvest3491how do you derive to this dosage? Any side effects with such high dose?
@@henvest3491
6 grams Is max safe for long term use
Have you experienced any ill side effects?
Maybe our lives won’t be extended to a significant degree but taurine may help improve quality of life in our later years.
Give AI ten years to work on lifespan and we'll see if AI doesn't discover a gene that can be edited (CRISPR-Cas9) to significantly extend life.
@@stevechance150let's hope it doesn't figure out how to keep itself alive 😂
Yes if you eat 1g per kg of bodyweight of taurine like they did in the study. Every day :)
@@Nobody-NowhereYou will greatly benefit from taking 6 grams of taurine every day, other studies show.
@@sebk174 What study shows this?
Taurine caused my dogs cataract to go away. It came back years later but Taurine again helped.
My kitty was literally dying of heart disease. L Taurine brought him back and he lived quite some time after that.
Cats know ALL about Taurine... (and so do Cat Food formulators).
@kathleennorton2228 Please share the supplement brand and/or source.
@@avarielblackwing6613q1
I cook for my dogs. There are many vets saying to add it to the food. I've been trying to research taurine. Thank you.
@sunrae7680 veterinarian secrets videos look it up , Canadian vet cooks food for dogs and cats , I believe his recommended added turine supplements and dosage .
well done. years ago, i found a book where a woman claimed to cure her asthma using vits a(retinol), c and e. it worked for me too. then it stopped working. but i noticed it worked after i'd eaten a tin of smoked oysters. i worked out it was the high level of taurine in oysters that was what enabled my body to make use of oil-based vitamins like retinol and vit e through the production of gall. i hope this information helps.
N = 1
@@KyleHohnOr N of 1.
@@KyleHohn Sure, but you can't just wait around your whole life for every conceivable scientific experiment to be performed and verified now can you?
@@LagMasterSamI don’t get out of bed unless there’s an NIH meta analysis that says the best part of waking up is Bayesian inference in your cup.
@@KyleHohn That's hilarious, I'm going to have to borrow that line. But you know if you wait too long for NIH meta analyses, you may not wake up one day to enjoy the Bayesian inference aroma when it arrives... If an N of 1 effect is large enough and easy/harmless to replicate, it may be worth exploring.
Based on the content of the video, here's a summary of the key points discussed regarding the study on taurine and its potential effects on lifespan, health span, stem cells, and cellular senescence:
1. **Lifespan and Taurine Levels:**
- The study measured taurine levels in blood across different biological systems, including mice, monkeys, and humans.
- In humans, taurine levels decrease with age, with a significant reduction by age 50.
- Mice were fed either a taurine-supplemented or non-supplemented diet. Those supplemented with taurine had a 10-12% longer lifespan compared to the non-supplemented group.
- Notably, taurine supplementation began in middle age for the mice, suggesting its benefits can still be realized later in life.
2. **Metrics of Health Span:**
- Taurine supplementation led to reduced body fat, improved muscle strength, and better blood sugar levels.
- Bone health was positively impacted, with increased bone volume and improved bone strength observed in taurine-supplemented groups.
3. **Stem Cells and Cellular Senescence:**
- Stem cells are crucial for healing and defense against pathogens, while senescent cells can negatively affect surrounding cells.
- Taurine supplementation was associated with reduced cellular senescence markers in various tissues.
- An experiment involving gene analysis suggested a potential increase in mitotically active stem cells due to taurine supplementation.
4. **Correlations and Interpretation:**
- The study had animal models (mice) as well as data from monkeys and humans.
- Positive correlations were found between taurine levels and various health markers, including reduced inflammation and obesity.
- There were also negative correlations, such as dyslipidemia and elevated liver enzyme levels, that were not extensively discussed in the video.
- The presenter emphasized the need to consider both positive and negative correlations and to avoid oversimplifying the results.
5. **Application and Implications:**
- The presenter was cautious about the interpretation and emphasized the potential but speculative nature of the findings.
- While taurine might not extend human lifespan by 12%, it could still have significant effects on overall health.
- Taurine supplementation later in life could be impactful, potentially compensating for earlier lifestyle habits.
- The presenter suggested watching their detailed study analysis for more comprehensive information on the findings.
That was a brilliant and succinct summary, thank you.
I will be placing an order for Taurine with Amazon. I'm 61 and feel as though my batteries are constantly flat.
Thank you for posting your clear and succinct summary. Very helpful. ❤️
thank you ChatGPT lol
@barrycrump6189 how has it gone so far? What mg?
Thank you
I am 69 yoa. I had been taking 1grm/day taurine for 5 years. The new study on taurine up to 6 grms/day is game changing for me. So, I have several decades more extension in my healthy lifespan.
A teaspoon is 6 grams
Don't forget glucosamine, it significantly reduces all cause mortality and drastically reduces cancer rates and tumor growth while also helping joints and so on. 1500mg a day
@@rrriggt6444 Thanks ❤
@@rrriggt6444 Hmmmm. My taurine package says that a teaspoon is 2 grams.
One of the biggest problems with mouse studies, apart from the obviously massive gap in genetic makeup, is that their standard laboratory diet is extremely poor and unnatural. They are fed primarily corn and soy, both usually GMO. So basically any change in diet, or supplementation, may show an improvement where a more natural baseline diet would not. We just don’t know.
That’s also how fad diets get started in human populations: the standard American diet is so poor in nutrients and rich in pollutants that almost any change will yield improvements.
Right, so you can eat crappy for years and still be able to improve your life span by supplementing taurine. 😊
Where did the previous reply go??
Well said..
Right, people are brainwashed by the food industry to eat garbage when animal fats and proteins are the best things you can eat and soy and wheat grain whatever slop was just there to keep millions of people from starving to death- yeah it’ll keep you alive but not very well.
@@thomasgellos1732 maybe shad#owba#nned if you mentioned chews, races, genders or other taboo topics..
Since I feel having being called out I want to clarify some things:
1) the fact that I use your videos for taking naps doesn't mean I don't follow them, when I wake up I usually start again to the last thing I remember
2) it means you have a nice calming voice
3) I also use Andrew hubermann's videos for the same purpose because he has a warm calming voice.
Haha, you are always welcome to nap to my videos.
OMG same!!!! Both content are fire and both lead me to deep satisfying sleep
@@cassandrapno This guy needs an AMSR spin off channel
Same here. Also Sean Carroll's AMA videos for 3 hours of science and philosophy.
Im not Alone 😂
I'm 44 years old, and I take taurine every day.
I've been working in shifts for 18 years.
Taurine is a salvation for my sleep, and as I train every day, strength and cardio it helps a lot to endure shifts, sleeping during the day and daily physical exercise.
What's your daily dosage?
@@LL-hs4jo 1000 mg once a day
@@ruimarques1979What time of day do u take it? Bedtime??
@@sncnutrition7118 before bedtime
Does taurine come in capsules
I’ve read it helps with tinnitus. A lot of people would love to hear you address that.
Taurine maybe makes a small difference, but one thing I tried which made it almost inaudible is GABA supplement.
I've suffered tinnitus for over 20 years. I'd love to know the brand/dosing you're using for such great results.
A lot of people would love to hear -someone with a tinnitus probably
I'm practically a 5 year old when it comes to these topics so I appreciate being taught this way! Thank you
Haha, I appreciate it.
@@Physionic are you saying you had so much taurine you reversed your aging to that of a 5 yr old?
@@-.____________________________i took a kilo of taurine and now i am waiting to pop out of my mom again.
its past bedtime junior!
Chill 😂🎉👍
I'm nearing 70. As diabetic from the past (eight years on insulin after a heart attack), fasting one day a week (for 36-40 hours) led to improvement in A1C. Having been encouraged by this, I went aggressively for HFLC diet and overnight fasting (found out I 'm good at it!) with 7,000 steps everyday (sometimes within the house because of inclement weather) for over 7 months.
However, I noticed I wasn't producing enough energy to go up a hill and my LdL and total cholesterol had gone up (and LdL above the range for the first time). The triglycerides remained below 80. A1C was 5.4. I had lost over 35 pounds and reached a BMI of 19.5 which worried my doctor.
So I went for a week-long program (over the net) run by a famous doctor (doing research first using Atkins then Keto for over 25 years) but they were unable or unwilling to talk about how to address "low power". The course was mainly for people who had high BMI. I then went for an exercise bike after getting fooled by studies on "Italian alpine cyclists".
Now after another 15 months, this June (2023), after 22 months being out of any medication for diabetes but still with "low power", I found you. You made me realize the folly of many things including "insulin resistance" for those who have no weight to lose. I had already played with relaxing the A1C to a steady state of 6.5 but now with LdL and total cholesterol both within range. I had also realized since the beginning of 2023, that one thing is autophagy but another thing is to have cell death. Lactic acid production from that "cyclist trainer" made cell death possibly worse.
So I am increasingly saying: "it's the health of the mitochondria stupid". It's clear for me it’s less calorie, be it from carb or fat (that's from you - thank you), and with supplementation to reduce ROS. The Taurine study, as many of these studies go, is mainly for overweight people and those with blood sugar issues.
@surajitgoswami1871 About your cholesterol levels. There are many people whose cholesterol levels look similar to yours after being on a HFLC diet. I’m not on that type of diet but I joined a Facebook group called “LMHR” (lean mass hyper responders) to see what the fuss was about. There are a lot of people in that group whose LDL cholesterol skyrockets into the 300-400+ range with other cholesterol markers remaining normal. Those extremely high LDL levels seem to be associated with normal to low BMI and extremely low carbs. There was a recent study that showed that association. Just bumping the carbs up will (should) start to bring bring tour LDL down. Btw… I’d be worried about a BMI of 19.5 too
@@pacmanflI understood, perhaps im wrong, but in my readings the higher cholesterol was due to the fact that that is how fat sourced energy like ketones gets transported to cells. But I’d be grateful for further education.
@@sheppycider123 Here’s a link to a video discussing the LMHR phenomenon. In the comments section of the video you’ll find a link to the paper published in 2021. It was an observational study so there’s that, but it seems valid. As for the causes and consequences, it seems to be speculation at this time. This is only a curiosity to me so I haven’t really got that deep into the details. th-cam.com/users/liveq7O2DcO6Xl8?feature=share
@@pacmanfl I do not find your conclusion about bumping carbs as the only let alone optimal solution. I went on LCHF keto diet and my LDL skyrocketed to the level, that my doctor wanted to put me on statins. I declined and decided to fix it with change of diet. I was still on very low carb keto diet, but I stopped to consume saturated animal fats and replaced them with olive oil and coconut oil. After several months my LDL dropped more than 50%. So I did not need any carbs to achieve it.
Now I do not really think that LDL is such a problem and I am actually on the carnivore diet, which means lots of saturated fat and no carbs at all and I feel the best so far. I do not check my LDL, though, because I do not want to be pushed into statins.
@@neilnewinger3059 I didn’t imply that bumping carbs up was the only strategy for lowering LDL. As I mentioned, this was an observational study. The amount of saturated vs unsaturated fat consumed was unknown. However, in the discussion and supplemental data, LDL was significantly reduced with the introduction of 50-100g of fruit and starchy vegetables. The study drew no conclusions on the cardiovascular risks associated with this phenomenon. Are you 100% sure that an LDL in the multiple 100’s is ok? If you are then you know more than the people who research this for a living.
I take 2 grams first thing in water every day, I am 74 years old and think the benefits outweigh the negatives I weight train twice a week pushing hard increasing weight or reps every workout, this I find is all good, I add creatine every day also.
Creatine is good but i swear after a while it lowers libido.
How are you doing now? Do you take creatine separately from each other or does it make a difference ? I’m just starting to take creatine ❤
@@toriwolf5978 Hi I take 4 grams a day now of Taurine first thing on an empty stomach, then with breakfast a multi Vit and creatine + Vit D3 & K2.
Feeling great and my skin is no longer getting bruised with every knock, so good news.
@@toriwolf5978 Really great TBH, it's just improved everything muscle wise. and health. I have upped it too 4 grams every day
Thank you for being truthful and nuanced while still keeping it fun, I wish we had more content creator like you, cheers
Spot on thanks 😊
Important to note that there are plenty of ways to get taurine. Diets high in meats and fish will probably have all the taurine you would need. As far as im aware, seafoods are the most abundant sources of taurine naturally. This could be one reason people in southeast Asia have such long lifespans. Plenty of taurine found naturally in their diets.
And that is why they cost so much....
Looks like Red Bull gives you -wings- youth. Seriously though, Energy Drinks are packed full of Taurine. Now that I know, I'll double down on drinking them.
Energy Drinks are the actual best source of Taurine. Are you serious? I hate Seafood.
Also why Asian women that are older than 60 look like they are in their late 30s
@@EmeraldEyesEsoteric 😂 go for it, I also hate seafood. Taurine is in a lot of energy drinks because it helps reduce jitters people may get from high amounts of caffeine
I like this guy he is well presented and offers up the study rather then just take my word for as most do.
Thanks!
Been taking it for 2 weeks and 3 days and on the 4th day I finally can feel the difference and I love it and feel great!
Subscribed! I'm 66 and have studied health and fitness on a daily basis for the past 30 years, learning something new on nearly a daily basis. I salute your clearly articulated narration and presentation. There are so many presenters out there that just do not speak clearly, nor present info in a logical manner. My daily supplement regimen has included taurine for over 20 years. When you hit 60, you body and mind will become more sensitive to finding the optimal nutritional balance point, aka homeostasis. I'm interested now in watching all of your presentations, and curious to know your thoughts on N-acytl-L Carnosine (which I also take).
I have heard that it has many health benefits, ( including ridding the body of parasites) how is it working for you? What has it helped you with, the most? ,*( If I'm not being too nosey, LOL)
Curious about your regimen, if you don't mind sharing
Homeostasis...not hemostasis. 😊
@@kathleensaenz4717 I'm the typo king.
As always, very unbiased clear and honest explanation! Thanks! And thumb up 👍
Much appreciated!
@@Physionic ...And I meant it really! I am benefiting from your scientific unbiased explanation and started with some supplements as Creatine, Whey protein, NAC, Glycine and Berberine!!! I have just ordered Taurine Today when I have just seen you latest video about that! I was a very sceptical guy about supplements because almost all web promoters of these "health advices" are charlatans who have something to sell like Dr. Berg and acolytes... But with your in-depth scientific studies it gives me more confidence and I want to live as healthy "strong" man for the rest of my life. So far I am doing very well! Thanks again. Also because I am a mathematical and IT guy I tend to admit the logic behind your research and explanation of the studies ☺
You do a great job of explaining challenging concepts and you do it with charm and humor.
Looking forward to the second segment on Taurine supplementation.
Same!!
www.ncbi.nlm.nih.gov/pmc/articles/PMC4712861/
Click bait…
Your channel is fast becoming one of my favorites! Thank you for the balanced way that you presented the information from the study.
Donkeys , monkeys and junkies
Watch out. He lies a lot. Is too lazy to do research
I am finding taurine helps with improvement in Gallbladder and Liver health. Increased bile production, and parasite removal. Taurine is a supplement I include as part of a way of life, and do not depend on it solely, or treat it like a medication. It works synergistically, and in my experience is best used from that point of view.
I totally agree with what you say but how can you make sure that it really helps and it's not placebo?
@@renelovemetal one could say that about anything
@@917hazel thanks for admitting that! So your answer is ?
@@renelovemetal Being in a constant state of low grade fear will leave one not in touch with how one feels and they will probably never know what is impacting them, especially in a positive way.
@@917hazel so you are not able to argument your statement
Kudos for an exceptionally clear, well balanced presentation.
I rarely watch health related programs, as so many make hyperbolic, unsubstantiated claims. The title "Nutrient of Youth" suggested this video would fit that stereotype. I would not have bothered watching except for wondering what Taurine is. Your source citation being the prestigious publication 'Science', immediately dispelled concern about baseless assertions.
Why do our bodies produce less Taurine as we age? What processes are we trying to compensate for? Does simply adding more to our bodies actually fix the underlying problem?
Aging is the culprit... Cells age and produce less. Supplementation slows this aging down. Heals the heart, cells etc. 👍🏼
Great vid! Please do one on Telomers and the anti aging process. This + DNA editing will and proper supplement nutrition and exercise will def. Increase lifespan
Taurine has been on my mind for the last few years and I'm so happy to have found this video (and channel!) that expounds greatly upon my interest. I'm currently using a health drink that focus' on taurine supplementation. Personally, I do have reservations per liver issues.
Taurine is quite promising for the liver.
I'd like to hear more about the bone growth aspect. Could this help with osteopenia, joint rehabilitation, dental health?
Yes.
A medical study showed a HUGE correlation between regular exercise with weights and increased bone density. Even for people in their 90's, their bone density increased by as much as 30%. It makes sense that exercise (cyclic stressing) engages muscles, tendons and BONES. There likely are publications on how best to begin/maintain a weight bearing exercise regimen later in life, what limitations apply, what dietary recommendation aid bone growth, etc. Another fascinating, non age related study pertained to astronauts. Even with regular exercise, their hearts atrophied by over a quarter due to the lack of gravitational stresses. But once they returned to earth, the heart quickly regained what had been lost. This provided another demonstration of how dynamically responsive parts of the body are to their use (use it or lose it)
Stop eating rusty iron filings promoted as 'iron fortification.' Anemia due to chronic inflammation is caused by iron overload in the tissues due to copper activated ferro-oxidase deficiency. Unfortunately, your doctor doesn't know this, and doesn't test for elevated iron in the tissues and assumes low iron in the blood automatically represents the iron level in tissues, which it empirically does not do. Look up 'Morley Robbins' for more more information.
@@wellnesspathforme6236the best way to resolve issue with "iron deficiency" is to take Floradix or increase folate - green leafy vegies and increase HCl in the stomach with betting hydrochloride before meals.
Best is to swap commercially raised on corn & soy red meat and dairy to grasspastured and grass-finished red meat organs and dairy from sheep & goat.
I added torine to my supplement stack. I take 2h in the morning and 2 gram in the afternoon. I also added glycine 5g after every meal. What I have read I think has similar positive affect. It reduces blood glucose, it reduces inflammation etc but it works on other aspects in the body.
Thank you!
This just showed up in my TH-cam feed, and I'm so glad it did!
I've been interested in and learning as much as I can about science, especially regarding health, my entire life.
My education and training has not been in the science or medical field, it's one of my favorite interests.
I love learning as much as I am able, it's a passion of mine.
So, Geek on!
The information you share will help so many people... including people who are so inclined, as I am, are able to Geek Out with you ❤
Thank you!
I’ve subscribed. Your attention to detail but cautious optimism is exactly what I’m here for. I experienced quite an unexpected potential benefit: I suffered 11 months of slight double vision in which my left eye would not come quite back to center when looking to my left and back. Just three weeks after taking two big taurine pills daily, it virtually stopped. No one can say whether it was taurine but I can’t help but make a possible connection. Thanks
Wow! Your analysis of the the data, pro and con, was spot on. Sadly, this type analysis is exceedingly rare
I added 1-2g taurine to my afternoon stack about 5yrs ago. It’s no magic bullet, but is beneficial along with other aminos.
What else Is in your stack ?
@@sigmahardy I follow my own protocol, but Blueprint by Bryan Johnson is a fairly close approximation of my own stack, which is also spread into morning, afternoon and evening.
I love that our generation is pretty much the test subjects for thousands of supplements
Every generation since “flower power” have been “test subjects”.
And "vaccines"
And that's good. We will filter out the bad ones.
Go further back. "Snake oil" ring a bell?
Pharma ,Food , Government use us every day since the 1950's.
Thank you for a totally unbiased evaluation this is very refreshing, as a type 2 diabetic i think i will sit on the fence for now loved the video.
This is awesome I have been taking tarine for 15 years I had a nature path to a neurotransmitter test on me and said my body was not making it and I needed to take it and it was huge cuz I suddenly calmed down Good to know that it will do all this other stuff too thanks!
Great video on the topic and a really fine example of how to critically think about scientific papers beyond the headlines.
You have the gift of balanced research synthesizing thoughts and teaching. A++!
Thank you!
for me taurine boosted vo2max. Easier to train from the very first try.
I'm afraid a lot of suplements has its own + and - . Its interesing for sure
Interesting...
How did you measure the VO2max increase and how much did it increase?
Did anything else change?
@@aarondcmedia9585 Simply can swim longer.The same heavy weight training program goes easier too. No need to measure its obvious for me. 3-4 grams 30min before training and youll feel it hopefully too.
Creatine is a must too i use it for months now...
BTW this morning ,fasted, after 1 gram of taurine and coffe had 1 hour walk and at the end i began to run i was full on energy. I dont like to run and ecxaust fast,but i just couldnt stop this time. I decided to watch my limits and in the end my heart started to hurt a little. Very rare for me. But funny thing i was not tired at all and could continue stopped just because of the heart which wasnt very racy too.
I cannot tell more about taurine i use it for several weeks and before workouts only
What I found with 1000mg of taurine/day was after one week 1. Libido was increased. 2. Night vision was decreased. 3. After one week the night vision component is still reduced but less than at first unless two doses are taken. During my morning walk before daybreak I look down the path to the end where a grey bench sits. Before taurine I could see this bench and surrounding trees. Now I must be half way down the path to even see the bench but it is slightly less visible at 1/4 mile in the dark depending upon lunar state. Night vision is important to me.
taurine is great for eyes health actually.
Nice job, the thing with a scientific study is that it is one study. The thing that makes good science is repeatability and if results stand the test of time.
Agreed!
In the chart in your video, N-Acetyltaurine (NAcT) is strongly associated with kidney disease. "NAcT is an endogenous metabolite. Biochemically, N-acetyltaurine is formed as a result of an acetylation of taurine." Alcohol metabolization in the liver is listed as the primary driver of the conversion of taurine to NAcT. Would supplementation of taurine require one to avoid alcohol? Also, many American's sufferer from non-alcoholic liver disease (from over consumption of carbohydrates). Would this also increase their risk of taurine to NAcT? If so, would we see a dramatic increase in liver and kidney disease with use of this supplement?
*previous* kidney disease
I read years ago that taurine was recommended for vegans so I've been on 1,000 mg per day for years. I have a genetic disorder called PCOS which, among other things, increases my risk of diabetes, despite my super healthy lifestyle and normal weight. My latest blood tests are in the pre-diabetes range. Very discouraging. As a now-70-year-old, I will continue my healthy no-sugar diet and exercise, as well as the taurine. Thanks for this video!
Research reishi mushrooms (Ganaderma lucidium), known for thousands of years to extend life.
Or, just eat sustainably raised, organic, grass fed beef.
Learn about intermittent fasting. I suggest the book called 'Fast Like a Girl." I've been a dietitian for over 35 years, now retired, but still very active in terms of continuing education. Intermittent fasting, assuming you're a healthy person, can help with insulin resistance in a BIG way. It's much easier than you would think and very safe but it's important to learn about it and recognize that men and women have to do it differently because we are so different hormonally. Work smarter not harder when it comes to health. Knowledge is key. If you overdo working out you're going to raise your cortisol which RAISES blood glucose adding to insulin resistance.
Fast...like a girl...sounds perfect ❤as I've been currently fasting...much different than when I was in my 20-50...could loose 15-20 lbs in a weekend! Now barely loose 2 lbs ...that come back o as I drink my 2 glasses of lemon ginger cayenne and tumeric water....then maybe cup or two of coffee...Weigh myself and 2 lbs have added back , to my beginning weigh....
Taurine sounds great to my Knees,if it activates my Stem Cells to build ...❤
Look into b1 in benfotamine or tmp. Also berberine? Just a thought..
Any opinion on why the box is red for previous kidney disease? Every comment I read says the opposite when it comes to taurine and kidney disease?
My reading of the video, is that the red box is for inverse correlation, that is, taurine supplementation leads to less kidney disease.
You deserve a larger audience! Your presentation is way better than than I have come to expect!✅ I'll be frequent visitor. Thanks.
Wow! I am impressed! Excellent video, professionally done, well explained, etc., etc. Thank you so much for taking your valuable time to share this with us!
www.ncbi.nlm.nih.gov/pmc/articles/PMC4712861/
First time; YT sent me. I like your style and information and delivery. You’re a very I’d say innately talented, and solid teacher, your explanations are key to my staying power. And for me? I need things explained, as to why I’d do this or that, and not just the hyper excitement of new findings, but also the restraint of a physician with years of experience behind him.
I got that from you. And you’re too young, lol. So thanks!
Subbed and all thumbs up. 👍👍😊
would be cool if you made a video about bone density in general
So basically it puts the body back in a growth phase, something that optimizes repair when relevant at the cost of increasing the cancer risk, that white elephant in the room, I didn't notice you speaking much about except saying that some of the choices the body makes has the property of reducing the cancer risk and taurine seems to undo those choices.
After I read your post, I did some research about taurine and cancer. What I found was that it seems to inhibit cancer cell proliferation. So even better
Thanks! I really like when u simplified the data for us guys with a 3rd grade education , continue the good work 😊
Many thanks Nic for a very informative video. I am 65 and started taking Taurine a few months ago.
NERD ON!!!
Thanks for the balancing nuances.
Boron and magnesium changed my life. They cured my back pain. I take them everyday. I have had zero side effects. My back was really bad. Now I'm pain free.
How do you take them ?
How much boron per day in terms of teaspoons? Dissolved in beverage or mixed with food?
@markaguilera493 I don't take it by the spoonful. I went ahead and bought it in capsule form. It's sold on Amazon as Bio-Boron. When I did take it in powder, it wasn't much. Maybe 1/4 teaspoon in a large glass of water that i drank over a few hours. Boron is less toxic to humans than table salt. A test showed that salt is 1000 times more toxic. So, if you are off a bit, it'll be fine. I got capsuls because It's just easier that way. It's works great. I find it unbelievable that it works to kill my back pain, but if I skip a couple of days, I do feel a big difference.
@@teredavila572 I bought capsules called Bio-Boron off of Amazon. I just take them with my other vitamins in the morning. Don't forget magnesium too.
Me too
Just started taking it two days ago., with tuduca.I think I'm already feeling a difference... Crazy.. My legs are already feeling stronger.. My nerves are feeling a little better.. My arms feel stronger.. I'm not Even working out yet... I've been sick for over 12 yrs.. Recently started suffering from neuropathy.. My legs and feet went seriously weak.... On top of yrs of being sick with fibro or Lyme's?? I have spent yrs of trying to fix myself.. Drs can't or won't help if you don't have insurance to run all the tests .. Even with insurance it's too expensive to get healed.. I've found turkey tail and shelijet(?) helps allot then I added this stuff and really feeling a difference.. next I would like to try peptides...
I took taurine for a while. It is very good for hgh and deep sleep. It also mitigates the effects of MSG.
Impressive interpretation and presentation. No hype, just facts. Subscribed.
Your teaching style is informative and keeps one engaged 👍😎
I appreciate that!
I remember similar life extensions for mice fed with GLYNAC, would love to see mice on GLYNAC and Taurine together.
I've been doing that exactly and more for some time now. And i feel awesome 👌
@@FinTra_ Have you not gotten any depression symptoms since taking so much NAC?
@johnf.hebert1409 actually quite the opposite, my motivation is of the charts. Even compared to when i was 20.
@@johnf.hebert1409I'm mid 30s. I maxed out at 4g glycine and 4g NAC a day. That's split into two doses. I found it's better to split it or else I felt poorly.
@@johnf.hebert1409why would he
After 2 minutes of listening, I gotta say you don't need to worry about prolonging your life man, you'll outlive us all.
The goal is to live forever, not live longer.
@@runed0s86 forever is made up of longers put together, what are you on about
He's actually 140 years old. 😂
LDL is the cement recruited to repair the damage caused to the wall (arterial walls) by inflammatory foods (processed food, fructose, seed oils etc) and sedentary lifestyle. Hyper cholesterolemia is a secondary response to a primary damage. Repeated cement repair builds up and clogs the wall surface but only as a response to repeated damage from bad diet. Total cholesterol below 200 and above 250 correlates with higher mortality in a U shaped curve. Cholesterol is a major component of the phospholipid bilayer, myelin, insulin receptor and is also a substrate to various steroid hormones, heme, vitamin D etc.
Can you address the dosages that would be required to see any effect at all?
Why didn't you mention the red spot on kidney disease? Is elevated taurine linked to increased kidney disease? If so, that's important.
I have a genetic disorder that essentially speeds up the aging process.
Taurine has literally been a lifesaver👍🎯
So grateful to see the science come out on this and match the conclusions I myself had reached.
Dear friends & fam:
I don't normally say this, but...I fucking told you so!
I highly recommend increasing Vitamin C and nurturing your liver & kidneys along with all this via B vitamins etc..
Love your comment, lol.
@@Holy.HannaH vitamin C, magnesium, and thiamine are basically the trinity of absolutely essential supplements every body needs to function. thiamine gate keeps every biological process in the body, magnesium to a slightly less extent. Vitamin c and magnesium are critical to free radical aka inflammation from every biological toxin and infection attacking the body being neutralized and preventing the damage. Vitamin C is critical for the immune system to kill infections as it's the literal ammo turned into hydrogen peroxide by the white blood cell to kill the infection. Magnesium is critical for calcium taming in the blood and preventing the toxic effects of calcium. When a cell or part of the body starts to die calcium is always what starts entering the area. Vitamin C is critical for preventing bone issues not calcium. List goes on and on with what they do. Those three things are basically top of the food chain in their critical requirement.
After that it's hard to order anything. Vitamin D, iodine, taurine, glucosamine are all around great too.
@@WaterspoutsOfTheDeep I didnt see this before, I apologize..
My mutation is extremely degenerative and drastically alters the order & amounts of what the body needs.
While all those things you mentioned are indeed necessary, Taurine & Vitamin C very much top my list.
You speak of the gatekeeping but due to the mutation my 'gates' aren't even formed correctly.
I've been on my deathbed twice in the past year alone after suffering horribly with no treatment for over a decade and watched several family members die while everyone stands by pretending there's nothing to be done.
Taurine has literally saved my life, reversed many of the hundreds of disorders it causes, and allowed me to function again.
I applaud your knowledge & understanding of the biology of healthy cells, I wish more people did, but our current understandings are nowhere close to being 100% accurate and not everyone's cells are formed correctly to begin with.
@@Holy.HannaH ~ Hi, It's brilliant to hear how much taurine has helped you! How much do you take, daily? Many thanks,
All best wishes ^_^
My vet recommended it for my dying dogs heart and he lived months longer than predicted.
Sorry for your loss bro, I know it ain't fun.
Thank you for hearing, listening to the CAll. Glad you're in the number and sharing the space at this moment in time. I love you
Great Channel with discussion of positive and negative side of supplements. If you feel unsure to use Taurine supplements try to focus on food that contain Taurine
Fantastic! Thanks for the detail, at 52yo I’m learning new things everyday on my health and wellness journey. I’m subscribing and look forward to geeking out with you on your other videos! Thanks for posting! 🤗
Great video 👏🏻
I may have skipped over a part of the video or maybe not, did you talk about the studies on kidney health when taking Taurine? I’m not sure if there are any but after taking Taurine and getting the results amped up on the benefits I read that there is deleterious effect on Kidneys, I was wondering if anyone has read about this and if it’s valid?
MAGIC QUESTION ? 🙄🤔👍👌☘️☘️☘️
I'm in. What's the recommended protocol (dosage, frequency) for one wanting to get on this Taurine train?
I'm curious as well. I'd assume 2-3g.
@@josho.9530 From one of the papers I got 0.8 gram per 10 kg body wt. I think that was for monkeys though!
Thank you for the video. Your English is perfect and very proper. I am gonna look up the word brevity and intact in my dictionary. Thank you smart guy!
Ive used taurine fot years sublingually. I feel it improves inflammation and immunity.
I volunteer for the study , my idea for a study, where a catalyst, like Quercetin or French pine-bark extract is used to increase the effectiveness of Taurine.
Huge and remarkable if true, yet with the dosage of 1000 mg/kg body weight in Fig 1D (as well as subsequent figures), I would expect a much greater difference. It doesn’t look like the authors measured blood levels of taurine supplementation over time and the paper only answers some cursory questions of taurine mechanism, but this does leave the door open for some interesting experiments to be conducted next. Thanks for discussing it!
Exactly, they did mention that on rhesus monkeys they used 250mg per kg of bodyweight, it was comparable to the T1000 dosage for mice.
But even at 250mg you would need to consume 10-20g every day. And halving the dosage halved the effect. At levels that people usually use supplements, like 1000mg a day its a total waste of money.
All of these studies always use insane amounts, the same happens in every DHA/EPA study, they consume like 10g per day.
@@alaindelon5398
If you don't mind me asking Why do you take 2g a night, what for and how long been taking it ? What difference has it made ?
Please can someone help me ,I'm having a Brain issue everything becomes confusing for me now, even though math Was one of my strengths everyday... With the NHL on my brain stem I can't formulate ...lol
250lb x 2.2046kg = how many grams should I take ?
Oh so are my kg ? 551.15 ? X 1000mg = 551.150 mg ?
You have the patience and ability to make the complex be understandable.
I've been aware of taurine in a slightly different context. I have noticed that various people around the world who keep exotic and interesting animals often mention that taurine is key to their animal's health and well-being.
The dietary sources are fresh meat and bones and the consuming animals include foxes, cougars, dogs, and others. All of the animals sure look healthy and active and...long lived. Just sayin'. But, no joke, it's food for thought...and more scientific study.
I have a tub of taurine powder that I purchased as in ingredient for making homemade cat food. The product is for human consumption so I began taking it. have to more research about the dosage. The label prescribes dosage of 1/4 teaspoon (equals 1.42 grams) per day.
I appreciate that you tend well in the direction of evidence based science instead of opinion and bias. Thank you!
PLEASE Reevaluate lipid profiles wellness factors with the understanding that the cholesterol issue is not supported. Taurine helps with Magnesium transport. Probably better results with multiple vitamins and chelated minerals. Taurine is a mineral chelator and a transported to improve absorption.
I have been taking taurine 12 grams/day for cardiac effect to stop or reverse atrial remodeling after having atrial flutter for past 3 years. My LDL has been under 100 averaging 92. Lipid profile has been totally normal in this 73 year old male.
Hmmm... I eat high meat as is, but I wonder if Taurine might help me with overall cardiovascular health considering my VSD. Maybe it could help my knees too if the stem cell generation translates to humans at all. Microfracturing led to arthritis in both knees.
Sure . TH-cam university students
Any negative effects of that much Taurine?
my cholesterol has been thru the roof my entire life. i am 69. i just use lumbrokinase sometimes to clear my body of clots. i eat anything i want. i take taurine to bring up my gaba levels.
@@daveberube997 My research on Medscape and the NIH website has found it to very safe. In studies with treating cardiac arrhythmias taurine was studied with doses as high as 20 grams/day combined with L-Arginine. I have not had any side effects and take this dose to help cardiac function with my history of atrial flutter.
Could the increase in bone density/increase be related to the increase in muscle strength rather than directly related to taurine?
An excellent point - yes, you're right, it could.
Since stomach acid decreases with age, wouldn't it make more sense to take ONE supplement to increase stomach acid, which would then restore absorption of taurine and other amino acids?
Interesting... That seems reasonable. I think the other issue I have seen is that older people tend to eat less protein. I don't know if that's a doctor recommendation issue or just an overall issue with health as you noted.
Yes. Already do.
@@tracymullane8818, have you noticed a difference since supplementing for increased stomach acid?
Stomach acid alone isn't 100% the issue there, it would come down to gut health and if the gut is healthy enough to still absorb it. Look into MA Labs Veda-Gest. That's what you're asking for on the acid end.
Betain hcl
Okay, so I started taking 1500 mg Taurine(free form)/day after viewing this video. I've been taking it for a few days and the only effect I notice so far is that I feel sleepy all the time and sleep a lot. Would a lower dose be advisable?
Best explanations of what graphs mean on each axis. So many assume we can ready graphs at a glance
Thank you.
@@Physionicany reason not to take a 1000mg of Taurine and Glycine together?
Really good presentation. I have had some questions and concerns about the level of Taurine to continue at this later stage of life.
I don‘t know if it plays a role but Monster Energy drink is the only soft drink I can drink without feeling bad after effects : I only feel more energized ❤
Wondering if the added Taurin has an effect on my level of inflammation…
It's trash don't drink it
No energy drinks are good
Another awesome video! I look forward to watching your other videos on this fascinating topic!
I super appreciate when intelligent content is put together for all of us to consume. Just found you, now time to watch all your content! Thank you!!
Hello ! Tnk u for the great content!
Is there any clinical trials that show any medical indication in treating cancer with mushrooms? If there is any , can u pls review them ? Tnx❤
Great stuff physionic. Keep up the great work 👍
Wee willy
Might you discuss supplementation with taurine above a certain level versus dietary intake level of taurine?
✓100 grams of scallops can have up to 827 milligrams of taurine
✓yellowfin tuna contains up to 964 milligrams of taurine per 100 grams
✓seaweed (nori) 1,300 milligrams of taurine per 100 grams
Maybe this is the secret to Okinawan / Japanese longevity.
There was a very red box for “prev kidney disease” can you help me understand what that means . My Egfr is 55.
That heat map shows a negative correlation with the eGFR risk factor. And I think "prev" stands for previous... so what does a potentially causal link between previous kidney disease and higher taurine levels tell us? Physionic can you clarify?
Im 58, quite fit , train in gym, swim, long walks/run, golf ..started taking Taurine 2 weeks ago, i noticed a lot more energy, better overall mood, feeling of well being, better and longef sex.. taking 1000mg a day , sometime 2000mg a day... yes all around a great addition to my supplements.
Experienced a Main Coon cat of poor health; he lived 16 years although the Veterinarian had said early on, he should have already passed (Heart) shortly after his birth. The Veterinarian (U. of F.) did recommend Taurine be included in his specialized cat food. This Video went beyond my cat’s Docter’s explanation, and Buddy (Maine Coone) outlived his health disposition by more than doubling his years. Although his health rapidly declined and was put to sleep early in his last year. However, he and I enjoyed his added time. Now it is nearing my time, late but am going to start taking this additive (Taurine).
So you're saying not only did they live much longer (which is great news) but the quality of those additional years was also the real benefit
I am going to try it and see
@@eugenevoltaire8681that's the idea.
All natural amino acids are left hand molecules. However, when we synthesis chemicals we often mix left and right. This mistake would drastically reduce Taurine's effectiveness. Is Taurine a left hand amino acid?
Would love to hear your thoughts on the research of L-arginine and it’s effects on nitric oxide. Should we be supplementing with it for better athletic performance or as we age when our nitric oxide declines?
It helps 100% with citrulline. 500mg and 500mg. One thing it can supposedly do though is fuel cells. So good and bad cells. Take it with a grain of salt.
I like your way of explaining things.
Very nice video.
Keep it up, Nick 👍
thanks for coming through man. so there are things i have to worry about. it seems good to take it. i guess we have to wonder what dosage is best to take Taurine. maybe that would make it much safer.
You don't, you can read the paper. They used extremely high dosages, they gave 250mg per Kg of bodyweight to the monkeys. This means ~20g per day for a ~70kg individual.
So unless you are into supplementing megadoses of taurine every day for the rest of your life, dont waste time on this nonsense.
I watched a video about 4 months ago on the benefits of taurine. I think it was with Rhonda Patrick. There were other medicos there too. They were saying that the benefits of taurine quickly disappear after you stop using it, like in a day or two, so you have to take it forever to get any longevity benefits. Do you know anything about this?
I added taurine to my daily regiment for 2 months and noticed no difference. I am already using whey isolate which may already include taurine but it is not listed. I was taking 2 servings a day for 2 months. When I ran out I did not re-order. Noticed no difference after stopping it’s use either.