Late-night eating and melatonin may impair insulin response

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  • เผยแพร่เมื่อ 19 ก.ย. 2024
  • Melatonin isn't just a sleep hormone. In its role as a regulator of circadian rhythm, it regulates over 500 genes. One of the important functions emerging evidence suggests it plays is in the regulation of insulin production in the pancreas, where it binds to receptors and signals the temporary (overnight) suppression of insulin production.
    This wasn’t a problem in our pre-industrial past, but in today’s environment of 24-hour food availability, it can have far-reaching effects on health. When food consumption regularly occurs outside normal daylight hours, the risk of hyperglycemia - higher than optimal blood glucose levels - increases. Chronic exposure to elevated glucose increases our risk of developing diabetes and other metabolic disorders. But, over time, elevated blood sugar - even within just high normal ranges - has an association with brain volume losses in the hippocampus and the amygdala, areas involved in memory and cognition.
    ▶︎ FoundMyFitness Episode Page (with show notes):
    www.foundmyfit...
    ▶︎ Interview with Dr. Satchin Panda:
    www.foundmyfit...
    ▶︎ Featured episode highlight:
    • What time to start eat...
    ▶︎ Support future FoundMyFitness episodes:
    www.foundmyfit...
    About FoundMyFitness: Rhonda Patrick has a Ph.D. in biomedical science from the University of Tennessee Health Science Center, and St. Jude Children’s Research Hospital. She also has a Bachelor’s of Science degree in biochemistry/chemistry from the University of California, San Diego. She has done extensive research on aging, cancer, and nutrition.
    It is Dr. Patrick’s goal to challenge the status quo and encourage the wider public to think about health and longevity using a proactive, preventative approach.
    Learn more about Dr. Rhonda Patrick and her mission for FoundMyFitness at www.foundmyfitness.com
    #melatonin #circadianrhythm #insulin

ความคิดเห็น • 727

  • @FoundMyFitness
    @FoundMyFitness  5 ปีที่แล้ว +119

    Hi, guys! This new video features a prominent clip from an interview with Dr. Satchin Panda. If you find this circadian rhythm stuff interesting, I suggest giving him a follow over on Twitter at twitter.com/satchinpanda (easily one of my favorite scientists to follow). He also has a great book out called The Circadian Code, which you can find at all major book suppliers. You should also consider watching both interviews with Dr. Panda found on this channel and on iTunes.
    If you're interested in helping us keep great content like this coming out, make sure to join our pay-what-you-can tribe of supporters for the low, low price of whatever you want to pitch in at foundmyfitness.com/crowdsponsor. Lots of new interviews are on the way! As usual, thank you for watching.

    • @goodgood9955
      @goodgood9955 5 ปีที่แล้ว +6

      Pregnant RP looks radiant!

    • @rajatbansal512
      @rajatbansal512 5 ปีที่แล้ว

      @@magicdoggo4883 actually lean protein sparks your insulin.

    • @veejayroth
      @veejayroth 5 ปีที่แล้ว +1

      Hi Doc, I have this question regarding the chart provided in the video that shows the 3 different insulin spikes.
      The question is: Were the subjects fasting for the same length of time before the meal? Or was the only "fast-breaking" meal the breakfast? This alone could change the validity of the interpretation significantly.

    • @DangerousConspiracyTheories
      @DangerousConspiracyTheories 5 ปีที่แล้ว

      Thanks, can you do a video on HCL?

    • @annetteyoutube742
      @annetteyoutube742 5 ปีที่แล้ว

      @justin friebe ....do you have a routine sleep schedule? (same sleep/wake hours most days?) Ever test your blood sugars? Are you at a good body weight? Asking these questions to assess how your body may be handling sugars, or if you're eating more than your body needs.
      Suggestion: start where you are, then experiment.
      Stop everything except water 3-4 hrs before your sleep. Also make sure you follow the "Sleep Hygiene" principles to optimize the sleep you get.
      And as RP mentioned, have a span of 12hrs where you don't consume food or drink (but absolutely do drink water). So if you stop eating at 3pm, don't eat until 3am, but start where you are, and gradually increase this time as it feels comfortable (even increasing by 30 minutes each week until you get to 12hrs). You can do this every day.
      Yes, that would be interesting to learn how different sleep schedules affect us. I think there is some difference, but you can still do what you can to support the process.

  • @grizzly9960
    @grizzly9960 5 ปีที่แล้ว +189

    Your speeches on Vitamin D probably added many years to my life. I am no longer vitamin D deficient and no longer get head aches or high blood pressure. Thank you!

    • @gabbygonzaga552
      @gabbygonzaga552 5 ปีที่แล้ว

      Did you supplement? If so which?

    • @UntakenNick
      @UntakenNick 5 ปีที่แล้ว +3

      Yeah, amazon owes her big time.. at least I started taking D3 and K2 because of her.

    • @UntakenNick
      @UntakenNick 5 ปีที่แล้ว

      @@PaulSchneider-bp2ic What's strange in that?

    • @akuma2892
      @akuma2892 5 ปีที่แล้ว +3

      @Paul Schneider208663531 I'm assuming because so many started to supplement which were purchased off of Amazon.

    • @UntakenNick
      @UntakenNick 5 ปีที่แล้ว +1

      @@PaulSchneider-bp2ic You won't find high quality supplements in supermarkets.

  • @jmacris1
    @jmacris1 5 ปีที่แล้ว +305

    please continue posting, very much valued

  • @MrKen59
    @MrKen59 5 ปีที่แล้ว +40

    I witnessed this in my own body while wearing a CGM. When I saw my glucose rise at night and remained high until nearly 4am, I realized how eating at night is not s good idea. This is a huge revelation to me.

    • @no22sill
      @no22sill ปีที่แล้ว

      Around what time were you eating and what time did you go to bed?

    • @MrKen59
      @MrKen59 ปีที่แล้ว +1

      @@no22sill 9-10pm and bed time is around 11. My understanding is your pancreas releases less insulin as melatonin increases.

    • @Primetime_dads
      @Primetime_dads หลายเดือนก่อน

      @@MrKen59yea i can eat a peanut butter jelly sandwich right before bed and wake up 5 hours later and glucose is 140
      I did this last night, ate the sandwich at 9pm woke up at 2:30am and checked glucose and it was 140

  • @chronia13
    @chronia13 5 ปีที่แล้ว +8

    Rhonda, you're doing us all a great favor by translating academic literature for the layman who can't cannonball into the literature past the abstract. There are plenty of academics that do similar work, but you have the qualities of being passionate about your field and the understanding that the rest of us don't have all the background knowledge that your colleagues do. Keep it up, this is great. Some academics get offended when they are asked to explain in simpler, more accessible terms, but I'm glad you are doing it at least part time. It shows mastery of a subject

  • @fred.flintstone4099
    @fred.flintstone4099 5 ปีที่แล้ว +230

    TL;DR: Don't eat anything 3 hours before you go to bed.

    • @bsmith6784
      @bsmith6784 5 ปีที่แล้ว +28

      I would starve.
      No, but really though. If I don't eat fairly soon before bed, I wake up in the middle of the night with my stomach growling.

    • @azb2010
      @azb2010 5 ปีที่แล้ว +32

      @@bsmith6784 You might be surprised as your body adjusts. I used to wake up hungry in the middle of the night, and there was no way I could skip breakfast or I would drag ass all morning. After trying intermittent fasting for 2-3 days, I found the early morning hunger was gone. Also, drink plenty of water. Sometimes your body craves food when you are dehydrated.

    • @previouslyachimp
      @previouslyachimp 5 ปีที่แล้ว +17

      @@bsmith6784 I never thought I'd say this sentence, but I agree with Knuckle Head! :)

    • @MB-up3mh
      @MB-up3mh 5 ปีที่แล้ว +5

      @@bsmith6784 Dude you're a food addict, try some fasting

    • @bsmith6784
      @bsmith6784 5 ปีที่แล้ว +1

      @@MB-up3mh I'm basically skin and bones, and always have been.
      No fasting for me.
      @Knuckle Head, I drink tons of water. Diet has gotten highly restricted though as I tend to eat the same three meals each day, plus a mix of snacks in-between.

  • @bidnow2946
    @bidnow2946 5 ปีที่แล้ว +33

    I really like this format and video length when presenting highly complex topics for the general public.

    • @valoric4767
      @valoric4767 5 ปีที่แล้ว +1

      Same. This is really great for sharing with other people. Normal people don't want to watch hours long interviews.

    • @skewsto
      @skewsto 5 ปีที่แล้ว

      Agreed. Short enough for sharing but detailed enough to wet the appetite for the long form discussions.

    • @Dockhead
      @Dockhead 5 ปีที่แล้ว

      problem i find is most if not all studies directly look at the type 2 of diabetes which is normally just known for people weigh issues or how the intake food and nutrients, where as type 1 is far more critical and not within the same circumstances completely.

    • @bidnow2946
      @bidnow2946 5 ปีที่แล้ว

      @@Dockhead I agree. Type 1 and Type 2 Diabetes are completely different diseases, and it is a shame that Type 2 Diabetes is even called Diabetes because of this confusion. Over the last decade there have been some attempts to change the label of this condition with "Syndrome X," "Metabolic Syndrome," and "Hyperinsulinemia," but if "Big Pharma" is advertising, that influences more people.

    • @Dockhead
      @Dockhead 5 ปีที่แล้ว +1

      @@bidnow2946 its just type 2 can even be reversed in some cases maybe even all im not too sure, its that im type 1 myself and most doctors even in England now are referring to type 2 cases and sound like they dont know enough of type 1, maybe thats why we have specialist nurses/doctors for type 1 diabetes mostly.
      metabolic syndrome i think is a very fair name to be given for type 2 just to show that both arent given from the same outcome.

  • @brakedchains2968
    @brakedchains2968 5 ปีที่แล้ว +18

    Rhonda you are strong, smart and feminine woman. World needs more woman like you. Salute from Serbia!

  • @keithesaf08
    @keithesaf08 5 ปีที่แล้ว +275

    That guy is melatonin, he put me straight to sleep.

    • @Kube_Dog
      @Kube_Dog 5 ปีที่แล้ว +6

      He's great, but I can't help laugh every time she refers to "Dr. Panda" with a straight face.

    • @CommandoMaster
      @CommandoMaster 5 ปีที่แล้ว +2

      What is the melody!

    • @Kube_Dog
      @Kube_Dog 5 ปีที่แล้ว

      @@CommandoMaster Here you can hear Panda singing a nice melody:
      th-cam.com/video/OQnNH7I07RY/w-d-xo.html

    • @endriu1201
      @endriu1201 4 ปีที่แล้ว

      Haha

    • @sterlingsilver5937
      @sterlingsilver5937 4 ปีที่แล้ว +10

      Your mom is melatonin...

  • @PeterCianci
    @PeterCianci 5 ปีที่แล้ว +4

    Great content Dr.! I usually eat my last meal around 8 p.m. and go to bed between 10-10:30 p.m. admittedly the lighter the meal, the better I sleep. Although, from time-to-time, I have been known to pound ice cream an hour before bed and feel amazing in the morning. So the "do things in moderation" suggestion heeds well here. Optimally...eating within an 8 hour period from 8 - 4 p.m. works amazingly well for accelerating "fat" loss.

  • @MemoTraining
    @MemoTraining 3 ปีที่แล้ว +18

    Weird how sayings such as "Breakfast like a king, Lunch like a Prince, dinner like a pauper" kind of come from an intuitive experience of past generations. They knew it was right to eat less the closer to sleep time.

    • @Tomy-im8zl
      @Tomy-im8zl 3 ปีที่แล้ว +2

      What's weird? you understand that a lot of intuitive experiences of past generation are debunk right? But yeah, some are true...

    • @MemoTraining
      @MemoTraining 3 ปีที่แล้ว +1

      @@Tomy-im8zl Wtf are you talking about sonny boy?

    • @Tomy-im8zl
      @Tomy-im8zl 3 ปีที่แล้ว

      @@MemoTraining It seems pretty clear, but I'm just saying that doing something from intuitive experience is not always a good thing but sometime it is. there is nothing weird in that.

  • @jasonbuck8349
    @jasonbuck8349 5 ปีที่แล้ว +1

    I love how articulate and knowledgeable she is. I definitely have a crush and cannot get enough of Rhonda's lectures.

  • @bfuller6109
    @bfuller6109 5 ปีที่แล้ว +143

    Great now I have to start drinking wine Saturday mornings instead of Friday night!!

    • @juliansosa2889
      @juliansosa2889 4 ปีที่แล้ว +3

      more time to enjoy it!

    • @sgordon8123
      @sgordon8123 3 ปีที่แล้ว +1

      Good point. A lot of late night calories are liquid ones aren't they? You can test your spike in blood sugar in response to different alcoholic drinks. I had never considered doing that at different times of the day before.

    • @ExecutiveCounsel
      @ExecutiveCounsel 3 ปีที่แล้ว

      Don’t be fooled by this sorcery. It’s not going to make any difference in the big picture. What time of day you consume food or drink has no effect on your overall health. What matters is what and how much you put into your body.

    • @GunninWizard
      @GunninWizard 3 ปีที่แล้ว +1

      hahahaha I literally started day drinking after this video..lost 12 pounds no joke..didnt chnge a thing except when I drink.

    • @ZameerHJ
      @ZameerHJ 3 ปีที่แล้ว

      You also should avoid at least 2 hours after waking up.

  • @DevonWayne
    @DevonWayne 5 ปีที่แล้ว +2

    You had a baby?! Great bounceback and love the knowledge packed video. I can share this to people who say I "starve myself" by not eating 12-16 hours a day or having 4-8 meals. I feel like no one knows how to eat, and the loudest people are the... largest.

  • @alphacause
    @alphacause 5 ปีที่แล้ว +2

    As always, every time I listen to you, Dr. Patrick, I learn something new that is seldom if ever covered by people in the low carb/paleo space. I really appreciate these valuable videos. Thank you.

  • @lupa6956
    @lupa6956 5 ปีที่แล้ว +4

    This is great, thank you, totally could have been written for me! I’m prediabetic, and it only happened since menopause. Low carb is helping, but my sleeping patterns are all over the place

  • @HighEnergyGirl
    @HighEnergyGirl 5 ปีที่แล้ว +2

    It is so cute how you are holding your baby!

  • @otishein9631
    @otishein9631 5 ปีที่แล้ว +27

    Dear Dr. Rhonda Patrick, thank you so much for your continued, free education of the public. You‘re greatly contributing to a more healthy society. My quesition is: How can athletes who are responsible to train in the evening (say ~ 6pm to 8pm) take your advice while still fulfilling their nutritional needs post-workout?
    Your answer would be much appreciated. Thank you again.

    • @billytheweasel
      @billytheweasel 5 ปีที่แล้ว +1

      From what I've read, athletes are unique. Both genetically and exertion/activity levels. Their lean muscle mass gives a tendency to be insulin sensitive and high metabolism.

    • @alfin3644
      @alfin3644 5 ปีที่แล้ว

      Otis Hein try a teaspoon of vinegar, it makes cells take up glucose.

    • @defeqel6537
      @defeqel6537 5 ปีที่แล้ว +1

      You don't need as much insulin if you use up all the glucose you consume. So I would assume, post-workout meals should be light on carbohydrates (but you need some to replenish muscles).

    • @MrWhiteav6
      @MrWhiteav6 5 ปีที่แล้ว +3

      Contracting muscle doesn't require insult either, GLUT transporters are inserted and allow glucose to diffuse down it's concentration gradient. All you need to do is go for a walk, and it should lower your blood glucose.

  • @livelucky74
    @livelucky74 5 ปีที่แล้ว +12

    Cannot possibly have enough RP content

  • @atis9061
    @atis9061 3 ปีที่แล้ว +1

    You're fierce Dr. Rhonda, thank you. This really hit home, because night eating is an ongoing problem for me.

  • @100StrongManly
    @100StrongManly 5 ปีที่แล้ว +166

    Rhonda!! You look as young here as the same ones done 5+ years ago. Your anti-aging plan is working

    • @KeithFlint350
      @KeithFlint350 5 ปีที่แล้ว +9

      She's getting younger, not just not aging.

    • @jakeschleifer1303
      @jakeschleifer1303 5 ปีที่แล้ว +3

      100Strong Training what is her anti aging plan?

    • @LexaRulesca
      @LexaRulesca 5 ปีที่แล้ว +9

      wouldnt say younger, i would say she looks better, something about an untangible glow that some people get when they go this way

    • @Kube_Dog
      @Kube_Dog 5 ปีที่แล้ว +4

      She a had a real beer gut in that interview, but now it's gone! Her diet works!

    • @elemenohpeespngrCortese
      @elemenohpeespngrCortese 3 ปีที่แล้ว +7

      Shes hot.

  • @TheFunnBinn
    @TheFunnBinn 5 ปีที่แล้ว +1

    You're awesome, Dr. Patrick. I have great faith in the information you put out there, and you and your podcast guests have a very large effect on my lifestyle decisions. My Beck depression checklist scores have come down steadily from 48 in early February, to 10's and 8's over the last week, and your micronutrient smoothie and Dr. Walker's information on the effects of sleep deficits (and how alcohol before bed can blunt REM sleep, which is needed for emotional regulation) have played a HUGE role in that. ... Had my first 70-degrees-for-10-minutes broccoli sprout shake yesterday too. ... You and the information you put out there have had a huge positive effect on my life. You rock!!! Thank you!!!

  • @zavensaroyan5388
    @zavensaroyan5388 5 ปีที่แล้ว

    These bite-sized summaries are excellent. I imagine you will get 4-5 from each interview. Very helpful when time is limited. Thanks Doc!

  • @robertshowe2417
    @robertshowe2417 3 ปีที่แล้ว +1

    Exactly the information I was searching for. Thank you.

  • @taemoorkhan6105
    @taemoorkhan6105 4 ปีที่แล้ว +1

    Listening to your wonderful videos at 0.75X speed reduces cortisol and increases serotonin in my blood. FYI @FoundMyFitness

  • @RobT07
    @RobT07 5 ปีที่แล้ว +6

    Awesome as always Dr. Patrick. Thank you.

  • @billlittlejohn2331
    @billlittlejohn2331 3 ปีที่แล้ว

    Thank you for posting this! You just showed up in my feed for the first time and I do have type 2 diabetes and have been talking melatonin to help with sleep. I'll quit taking it today. Again thanks for the video!

  • @davidrowe9402
    @davidrowe9402 4 ปีที่แล้ว +1

    I love watching enthusiasts.....as distinct from optimists... Rhonda is terrific...As a 36yr high school teacher, stuff like hers keeps me buzzy about my love of learning.. David. Melbourne ✌️

  • @pablopenguin24
    @pablopenguin24 5 ปีที่แล้ว

    Wow I'm really impressed with how professional this has become. You always have such valuable information to share, but now it looks like you have way more resources for making the video as professional as possible. Amazing work, and thank you for working so hard to share the info with us all!

  • @alexkasimir9931
    @alexkasimir9931 5 ปีที่แล้ว +2

    Great vid Dr. Patrick. First time hearing of melatonin insulin link. Thanks so much.

  • @ThyroidVsKeto
    @ThyroidVsKeto 5 ปีที่แล้ว +1

    Amazing short and sweet explaination. I had to find Dr Panda's Book "the ricardia code" to understand that skipping breakfast and eating late in the night wasn't doing any favours to my intermittent fasting window. Thanks so much for this!

    • @maztergee
      @maztergee 3 ปีที่แล้ว

      "The Ricardia Code" ?

  • @DodjiSeketeli
    @DodjiSeketeli 5 ปีที่แล้ว +1

    I eat late because I train late in the evening/night. Funny enough, if I eat *after* training, even if it's super late (around 22h, right before going to bed) my blood glucose is fine in the morning if my night was good. But if I eat late without training then yes I see that my blood glucose is elevated in the morning. By noon, though, BG levels are always ok. Oh, I eat one meal a day at night and I always train fasted, and I am not obese (~ 10% or less body fat, and I train 5 days per week). So what you do before eating late matters, I think.

  • @MrBluoct
    @MrBluoct 5 ปีที่แล้ว +1

    Thanks
    So much information from so many sources -minute by minute, day by day...
    Challenging
    Seemingly near a saturation point without demanding a context specific to the individual or further research by said individual
    Trends, new science, studies, podcasts, YT channels, journals...

  • @christopherho9956
    @christopherho9956 5 ปีที่แล้ว +7

    This video was so fire thank you for this Doc

  • @davidoneill2949
    @davidoneill2949 5 ปีที่แล้ว

    I just wanted to thank you Im studying nutritional therapy because of how interesting you've made this topic to me. Truly changed the trajectory of my life. So again thank you Dr Rhonda !

  • @arielporcheratv
    @arielporcheratv 5 ปีที่แล้ว +10

    Love your videos!!!! I've been binging your content for hours 👀

  • @rosarioperez7509
    @rosarioperez7509 5 ปีที่แล้ว +1

    Great video Rhonda!! Keep them coming.

  • @chapter4444
    @chapter4444 4 ปีที่แล้ว +2

    Dr. Rhonda I really value your thoughts, thank you!

  • @spiritflower6640
    @spiritflower6640 2 ปีที่แล้ว +1

    I'm happy to have found your channel and really look forward to delving into the helpful information. So my assessment fir myself, is from years of really high stress and not managing it well, and, developing sleep apnea, the high levels of cortisol I think helped to raise my blood sugar and create the situation that I have with high blood insulin and blood sugar and a fatty liver Etc. Alsi, been dealing with psoriatic arthritis fot about 7 yrs. I'm trying to deal with these issues through diet( and, no drinking alcohol) and supplementation, meditation, and regular light exercise, I would love to be able to do more but I just don't seem to have energy. I would like to understand more about why I still experience times when my blood sugar is feeling really low. I try to stay away from grains and starchy foods, but sometimes I feel like I need some carbs like sweet potato or butternut squash.

  • @theydisintegrate
    @theydisintegrate 5 ปีที่แล้ว +1

    IF by not eating in the mornings feels like hell to me, so I keep giving up on it. I get a headache and fatigue and depression, which makes me bad at doing my job. So frustrating! I really wish I could stick with it.

    • @diogofarias1822
      @diogofarias1822 3 ปีที่แล้ว

      It took me about 2 months to get used to it.

  • @bahaanaldo
    @bahaanaldo 5 ปีที่แล้ว +1

    This is exactly what I needed to hear. Really informative. Thanks for posting.

  • @aidanwitham344
    @aidanwitham344 5 ปีที่แล้ว

    Thanks Rhonda, your efforts are very much appreciated. much love to you and your family. 😊

  • @InSync3912
    @InSync3912 5 ปีที่แล้ว +1

    Dr Rhonda! You look sooooooo glowing and helathy and young! Do you do paleo and IF? Any particular secrets, please make a video on you daily meals

  • @josepena6053
    @josepena6053 5 ปีที่แล้ว

    Hello Dr Ronda, great video with substance to the point !
    Please continue posting
    Congratulations

  • @rafari9084
    @rafari9084 5 ปีที่แล้ว +2

    Thank you for what you do, it is greatly appreciated!

  • @jamienousey2891
    @jamienousey2891 5 ปีที่แล้ว +1

    Dr. rhonda you rock ! ty for releasing awesome content.

  • @davebelisle1653
    @davebelisle1653 5 ปีที่แล้ว +2

    I love your videos and the content, it’s s applicable, healthy and interesting! Thanks Dr RP!!

  • @LonersGuide
    @LonersGuide 5 ปีที่แล้ว +10

    Some of the best and most informative health and fitness videos available. Oh, and pregnant looks beautiful on you.

  • @brienq
    @brienq 3 ปีที่แล้ว

    Rhonda, I appreciate all the very useful and relevant information you share with us, but I wonder in this case if you looked at all of the studies of melatonin affecting blood sugar. There are quite a few studies showing improved insulin sensitivity, reduced blood sugar, and other improvements in other metabolic parameters. An exampel is found here, but I have seen others as well:
    Introduction: The use of second-generation atypical antipsychotics has an increasing role in the development of metabolic syndrome. However, these medications due to metabolic disorders can lead to an increased risk of cardiovascular disease and subsequently mortality as well as reduced adherence to treatment. The main objective of current study was to determine the ability of melatonin to reduce the metabolic effects of second-generation antipsychotics.
    Methods: This double blind controlled clinical trial was conducted on 100 patients aged 18-64 years old were treated with the second-generation antipsychotics for the first time. The patients were divided randomly into two groups of 50. The case group received slow-release melatonin at a dose of 3mg and the control group was given oral placebo at 8 p.m.
    Results: The findings in melatonin group indicated significantly increase of HDL and decreased fasting blood sugar and systolic blood pressure, as well as had statistically significant increase in waist circumference, weight and BMI compared with placebo group.
    Conclusion: According to the findings, it can be claimed that the addition of melatonin to atypical antipsychotics has led to a reduction in some of the metabolic effects of these drugs. In this study, HDL level was increased, and the mean systolic blood pressure and FBS were decreased in the melatonin group. Considering that these factors are contributing to cardiovascular disease as a leading cause of mortality in psychiatric patients, so the use of melatonin can reduce some of the medical effects of long-term treatment of atypical antipsychotics.
    Keywords: Melatonin; Metabolic disorders; Second-generation antipsychotic drugs.
    Copyright © 2017 Diabetes India. Published by Elsevier Ltd. All rights reserved.
    Randomized Controlled Trial Diabetes Metab Syndr
    . Jan-Mar 2018;12(1):9-15. doi: 10.1016/j.dsx.2017.08.004. Epub 2017 Aug 18.
    Effect of melatonin in reducing second-generation antipsychotic metabolic effects: A double blind controlled clinical trial
    Mansour Agahi 1, Negar Akasheh 1, Afshin Ahmadvand 1, Hossein Akbari 2, Fatemeh Izadpanah 3
    Affiliations expand
    PMID: 28847468 DOI: 10.1016/j.dsx.2017.08.004

  • @electricfire7
    @electricfire7 3 ปีที่แล้ว

    She is amazing along with Dr.Berg and co.These guys have helped me so much.God bless.

  • @littlesigh
    @littlesigh 5 ปีที่แล้ว

    More like these... this is great stuff. And provides evidence I can pass along for those still trying to figure thinks out.

  • @jimdandy8996
    @jimdandy8996 5 ปีที่แล้ว +1

    So what is worse, the elevated glucose levels floating around or elevated insulin floating around in order to bring down higher glucose levels? Its difficult to get a straight answer on that these days.

  • @billytheweasel
    @billytheweasel 5 ปีที่แล้ว

    I always hit the 'like' button whenever I open one of her vids.Always useful info.

  • @nicholastidemann9384
    @nicholastidemann9384 5 ปีที่แล้ว +2

    I eat one meal a day and go to sleep exactly an hour after I eat my one meal in the evening, and my insulin response is as good as it gets.

    • @discorabbit
      @discorabbit 5 ปีที่แล้ว +1

      I don’t eat anything I didn’t hunt or grow myself, sometimes going weeks or months without eating due to my lack of hunter-gatherer skills. My insulin response is superb.

  • @ebg3624
    @ebg3624 5 ปีที่แล้ว +11

    I have been eating between 12-4 everyday, I workout in the morning about 16 hours into my fast 🥰 I love this way of eating, I feel awesome and my body composition is awesome

    • @Re3iRtH
      @Re3iRtH 5 ปีที่แล้ว

      What kind of workout?

    • @ebg3624
      @ebg3624 5 ปีที่แล้ว +1

      I do 30mins cardio, running or rowing and then about an hour of resistance training 😀🏋️‍♀️

    • @AlvynArt
      @AlvynArt 5 ปีที่แล้ว +1

      how many meals do you have in that four hours?

    • @Re3iRtH
      @Re3iRtH 5 ปีที่แล้ว +2

      @@ebg3624 Awesome! Keep at it. I've tried before to implement IF but I found I don't perform as well at work (interpret medical imaging - diagnostic radiologist). Don't feel as sharp fasted. I eat 4-5 meals per day, and like you have an awesome body composition :) 9%bf by BodPod.. would love to get into IF for the possible longevity benefits if I could though.

    • @ebg3624
      @ebg3624 5 ปีที่แล้ว

      I eat 2 meals, first one is larger and the second one is lighter, no snacks in between but I will usually have a protein shake along with the food. I’m aiming for under 19% BF which for a non fitness athlete woman should be good for summer abs 😂 only about 2% left to cut wish me luck

  • @amyalvarado3762
    @amyalvarado3762 5 ปีที่แล้ว +1

    THANK YOU RHONDA💛⭐ FOR SHARING YOUR KNOWLEDGE 💗

  • @yoswayd5520
    @yoswayd5520 3 ปีที่แล้ว +1

    I believe this would make more sense to eat your final meal around 6 hours before bed especially if it is a larger meal. What this means is if you sleep at midnight you should eat a large meal at 6. My rationale is that your pancreas should be fully functioning at that point and you will need it to be for up to 3hrs following a large meal to regulate your blood glucose. If you eat that final meal at 6 and expect to be sleeping at 9 don’t be surprised if you have trouble sleeping because you ate a little too much too close to your melatonin production phase.
    I struggled with some insomnia recently and what seemed to help was eating larger meals 6hrs before bed. Also maintaining neutral calories for the day was important because if I was in a calorie deficit I would awake earlier than I intended and have less REM sleep. This means if you want to eat at 6 and sleep at 10 you should have a smaller dinner. Because dinner is a big part of your calories of the day this means you should have a larger breakfast and lunch than you may be comfortable with at first. But if you do struggle with insomnia and nothing seems to help, maybe this will help you as it helped me. Nothing is worse than being anxious because you’re in a calorie deficit at night but unable to sleep after eating because of a blood sugar crash or spike when you should be in bed. Do not try to spike yourself with food and sugar right before bed for the reasons stated in this video
    This also explains how my ex girlfriend who has type 1 diabetes would be able to sleep super easily even after eating late but I would be up restless for a few extra hours. Because she could inject her insulin she didn’t have to wake her pancreas up to do it’s job and so could sleep faster after meals.

  • @oscarcastellanos9270
    @oscarcastellanos9270 3 ปีที่แล้ว +16

    The more I think about optimizing my sleep the more stressed out I get = less sleep 🤷

    • @TheMancYank
      @TheMancYank 3 ปีที่แล้ว +7

      I sleep like shit and lately have been doing cardio, Yoga and weight training. I sleep sooooooo much better.

    • @Chxzz1
      @Chxzz1 3 ปีที่แล้ว +1

      @@TheMancYank hell yeah.
      I've begun doing intense 20min sessions about 30min after getting up and I sleep a lot better as well.
      Keep up the good work

    • @TheMancYank
      @TheMancYank 3 ปีที่แล้ว +1

      @@Chxzz1 Awesome!!! You too. I take some stuff called Stress Magnesium which helps right before bed. Well done.

  • @edmistarka6303
    @edmistarka6303 5 ปีที่แล้ว +1

    Very valuable post and looking forward to the next one!

  • @Michael-4
    @Michael-4 5 ปีที่แล้ว +1

    Keep them coming, you're the best!

  • @aubreyj.tennant1123
    @aubreyj.tennant1123 ปีที่แล้ว

    Without a doubt my sleep stats improved a lot when I eat a light meal (& no desert) early 3-4 hours before sleep. Lower heart rate dip by 4-5 bpm, higher HRV by as much as 35 points, longer REM & deep sleep intervals. These numbers are even good if I only get 5-6 hours of sleep. Thank you Doc!

  • @hikerJohn
    @hikerJohn 5 ปีที่แล้ว +2

    I never eat at night unless it's just some celery because I have GERD but it's good to know I'm getting an extra benefit :o)

    • @FoundMyFitness
      @FoundMyFitness  5 ปีที่แล้ว

      *Interesting discussion with Dr. Panda on GERD*
      th-cam.com/video/K-EY1gYDIlw/w-d-xo.html

  • @timdunk7278
    @timdunk7278 5 ปีที่แล้ว

    Great to know. Always exploring what is best to ingest, and now it's time to explore when... Thank you, Dr. Rhonda.

  • @ginoasci2876
    @ginoasci2876 3 ปีที่แล้ว

    awesome video.
    this information can reduce, prevent, and reverse many conditions.
    well done !!!

  • @Scottstunts
    @Scottstunts 5 ปีที่แล้ว +1

    Thank you so much for sharing your wealth of knowledge with us.

  • @ripperduck
    @ripperduck 5 ปีที่แล้ว

    Love this channel and presenter!! Thanks, Dr. Patrick...

  • @JanZamani
    @JanZamani 3 ปีที่แล้ว

    I'd like to see the strength of the evidence for this and the magnitude of the effect.

  • @tiffanyld7772
    @tiffanyld7772 5 ปีที่แล้ว +1

    I'd be interested in a pregnancy related video! Nutrition wise. Love all you do!

  • @AnimalFarmDance
    @AnimalFarmDance 4 ปีที่แล้ว +1

    what about whole food plant based lifestyle? great work!

  • @Kingaxel1
    @Kingaxel1 3 ปีที่แล้ว +1

    Love these short videos.

  • @vlun121
    @vlun121 5 ปีที่แล้ว +1

    I just ate a huge meal 2 hours ago and it.s 3 am. ... Ty for the advice.

  • @CmAstaJdaAzn1
    @CmAstaJdaAzn1 5 ปีที่แล้ว +6

    4:38 I felt personally attacked as I was learning cool info while sipping my glass of wine lol. Great stuff!

  • @veejayroth
    @veejayroth 5 ปีที่แล้ว +2

    Hi Doc, I have this question regarding the chart provided in the video that shows the 3 different insulin spikes.
    The question is: Were the subjects fasting for the same length of time before the meal? Or was the only "fast-breaking" meal the breakfast? This alone could change the validity of the interpretation significantly.

  • @shamanahaboolist
    @shamanahaboolist 5 ปีที่แล้ว

    Thanks Rhonda.

  • @MorganStuartGuitar
    @MorganStuartGuitar 5 ปีที่แล้ว +2

    I love your videos. You're so helpful.

  • @warkal868
    @warkal868 3 ปีที่แล้ว

    Thank you for this life saving information. Godbless.

  • @Charlestonkayakandfishing
    @Charlestonkayakandfishing 5 ปีที่แล้ว +1

    Best wishes to your family!

  • @synthryder
    @synthryder 3 ปีที่แล้ว

    Congatulations! Thx for helping me design recipes as well as make myself and others healthier!!

  • @justinmiller7422
    @justinmiller7422 5 ปีที่แล้ว

    My brain and body thank you for the new information! I will try my best to implement this into my life

  • @seanromanowski
    @seanromanowski 5 ปีที่แล้ว +1

    Informative as always, you rule Dr Patrick

  • @amnesiai
    @amnesiai 5 ปีที่แล้ว +1

    Your interview on rogan show was awesome!

  • @andrewtaylor9799
    @andrewtaylor9799 4 ปีที่แล้ว

    Thanks. I've altered my eating patterns based on this, and it fits in well with intermittent fasting...

  • @tm4tare
    @tm4tare 5 ปีที่แล้ว +9

    I have learned so much from watching Dr.Patrick's videos!I love her interviews with Joe Rogan!Nutrition and fitness goddess!!!

  • @coyotessong
    @coyotessong 5 ปีที่แล้ว

    I watched this twice attempting to understand what was being said, and still couldn't get it. Then I realized I could just slow the playback speed and, bingo, clear as day! She always has tons of quality information but my brain can't hang with fast talkers! It's just too intense and i shut down. :( Yay for Dr. Patrick on 3/4 speed!

  • @timonmees3043
    @timonmees3043 5 ปีที่แล้ว +1

    Thank you for making this video!

  • @westyw.4235
    @westyw.4235 5 ปีที่แล้ว

    Congrats sweet Rhonda! :) So glad to see your post again!

  • @bradbrockhaus633
    @bradbrockhaus633 5 ปีที่แล้ว

    I've learned so much from your videos...THANKS!!!

  • @velozdesign
    @velozdesign 5 ปีที่แล้ว

    Thanks Dr Rhonda Patrick, I have gained so much knowledge on health through your videos with Joe Rogan. I played them repeatedly until I understand what you are saying, because there are a ton of info.

  • @acorntree404
    @acorntree404 5 ปีที่แล้ว +1

    These videos are so informative. Cant wait to see more!!

  • @Nilsosmar
    @Nilsosmar 5 ปีที่แล้ว +1

    Thanks so much for all of the information.

  • @shepardforce
    @shepardforce 5 ปีที่แล้ว +3

    But the question that the study didn’t answer is “ what if the lunch or dinner were eaten as the first meal ? Or even as a post exercise first meal ?”
    Would the insulin sensitivity still reduced ?

    • @aussiesam01
      @aussiesam01 5 ปีที่แล้ว

      Yes it did.

    • @shepardforce
      @shepardforce 5 ปีที่แล้ว

      aussie sam it did mention three identical meals. But are they taken within a same day ( in which case the lower insulin effect might be due to a “second and third meal” effect), or taken as a first meal at different days. This detail isn’t mentioned.

    • @aussiesam01
      @aussiesam01 5 ปีที่แล้ว

      I thought it was pretty clear that the meals should be consumed in phase with the circadian cycle, which is in phase with daylight. This would seem to control the timing of the first meal, whatever you might call that meal. The exercise question is outside the scope of this discussion though.

    • @shepardforce
      @shepardforce 5 ปีที่แล้ว

      Still need confirmation from a study whether or not a morning first meal is better than a midday first meal. Suppositions and science are not friends.

    • @aussiesam01
      @aussiesam01 5 ปีที่แล้ว

      Oh dear, like a bald person haggling over the price of a comb. You're now arguing just for the sake of trying to show you had a point. No worries, I'm just happy to have the information that WAS contained in the video, it just adds to the accumulative knowledge on the topic. The other points I can wait for.

  • @davidr9876
    @davidr9876 5 ปีที่แล้ว

    We still know very little about the link between diet, hormone and health. The knowledge that IS out there is not taught to most doctors.

  • @lucu01
    @lucu01 5 ปีที่แล้ว

    Rhonda ! Missed you, thanks for the informative posting, as always

  • @vladynick
    @vladynick 5 ปีที่แล้ว

    Dr., I have SO much respect for you. Thank you for your insightful and informative videos and interviews (with Joe Rogen). I've learnt SO much from you and do try my best to follow your guidelines.

  • @birage9885
    @birage9885 5 ปีที่แล้ว +1

    Stopping too early will cause low blood sugar levels during the night, which will spark the release of stress hormones. I followed Dr. Peat's advice and have a bit of orange juice before bed and notice a positive difference in sound sleep. Think about it, after 4 hours your body is looking to normalize blood sugar, and if you don't provide any orally the body will stimulate organs like the liver and adrenals to solve the problem, next thing you know you have woken up due to high cortisol or andrenaline. That's the way I understand it.

  • @derektravers2024
    @derektravers2024 4 ปีที่แล้ว

    Not sure if you will get on an old clip but could do positive information on shift workers as our time to eat and sleep is all out .

  • @Kevin_Street
    @Kevin_Street 5 ปีที่แล้ว +1

    Don't eat anything at least three hours before bedtime. That's the way my Dad used to do it, but unfortunately I never manage to keep to these kind of rules.

  • @oldskooldriver9379
    @oldskooldriver9379 5 ปีที่แล้ว +1

    Very interesting research finds, thanks! Big fan of intermittent fasting, but I still crave savory/salty snacks some evenings, not carbs, not sugars.

  • @AnnaleishaMae
    @AnnaleishaMae ปีที่แล้ว

    Had to rewind and listen again in certain parts. V fascinating.

  • @JustinLietz
    @JustinLietz 5 ปีที่แล้ว

    Such a challenge for me to do this. My gym opens at 5am and closes at 10pm. I commute to work 30 mins away and arrive at 6am, get home at 3pm. I usually am able to get to the gym a little after 4pm, by the time I finish workout and sauna it's already around 7pm and post workout meals are important as far as I know, so this is definitely within the 3 hour window of my bed time. An ideal situation would be to find a 24 hour gym that also has a sauna so I can workout before work