Introduction to Mass Spectrometry

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  • เผยแพร่เมื่อ 27 ธ.ค. 2024

ความคิดเห็น • 214

  • @GodwantsU2knowZtruth
    @GodwantsU2knowZtruth 5 ปีที่แล้ว +63

    I wish when you go to school the Professors would teach you this way; many times you wish you didn't go to class because you come out confused all the more. Thank you for such a wonderful explanation.

    • @Whitelivesmatter148ate
      @Whitelivesmatter148ate 4 ปีที่แล้ว +2

      Meron G i can tell ur grammar teacher isnt doing u much justice either (ie. feeble use of semicolons and commas)

    • @yourfuturedocburenbeiya
      @yourfuturedocburenbeiya 4 ปีที่แล้ว +5

      @@Whitelivesmatter148ate What a nice way of showing your ethnocentric views here...Have you ever considered that maybe this guy isn't from the US? Because you can't possibly assume that only Americans are being taught this subject in English...

    • @adamtuner782
      @adamtuner782 4 ปีที่แล้ว

      @@yourfuturedocburenbeiya u're studying pharmacy or chemistry ??

    • @yourfuturedocburenbeiya
      @yourfuturedocburenbeiya 4 ปีที่แล้ว +1

      @@adamtuner782 Chemistry

    • @adamtuner782
      @adamtuner782 4 ปีที่แล้ว

      @@yourfuturedocburenbeiya of course

  • @edward3709
    @edward3709 3 ปีที่แล้ว +3

    what a legend u are. textbooks and other videos make it quite confusing but you cleared everything up in one go. Much appreciated

  • @anasofiavazquez3925
    @anasofiavazquez3925 5 ปีที่แล้ว +10

    I can´t belive somebody could explain it that easy. Thank you very much!

  • @JimRohn-u8c
    @JimRohn-u8c 7 ปีที่แล้ว +35

    Thank you so much for going in depth and leaving no stone unturned in your teaching. 5 minutes in and i could tell i was really gonna learn from this video!
    If everyone just taught like this (not leaving little details like the equation for m/z) no one would have to worry about bad teachers!

    • @Knowbee
      @Knowbee  7 ปีที่แล้ว +3

      Thanks so much for the compliment. Stoked.

  • @dr.debjyotipaul9840
    @dr.debjyotipaul9840 3 ปีที่แล้ว +4

    Simply outstanding!!! This is what real teaching is all about!!!

  • @chinmayeethakur5223
    @chinmayeethakur5223 2 ปีที่แล้ว +10

    This was so clear with respect to the detection aspect , none of the other videos could solve my doubts about detection .glad to having watched this one. Respect from India

  • @unnatigupta4867
    @unnatigupta4867 7 ปีที่แล้ว +56

    Superb explaination...I was struggling through the concept of MS now it's clear...thanks to u Sir

  • @mariociencia12
    @mariociencia12 4 ปีที่แล้ว +8

    Incredible! I (re)learned not just about mass spectrometry, but also about chemistry and physics in general

  • @asifalamjoy9530
    @asifalamjoy9530 3 ปีที่แล้ว +2

    As if Allah has sent an angel from heaven with all the info of mass spectrometer in this single video. I salute you boss. 😍😍😍😍😍😍😍

  • @Unaimend
    @Unaimend 11 หลายเดือนก่อน

    This is by far the best explanation on TH-cam

  • @lukem1151
    @lukem1151 3 ปีที่แล้ว

    this is one of the cleanest explanations for anything i have ever heard

  • @SaiyaraLBS
    @SaiyaraLBS 6 ปีที่แล้ว +6

    I am in love with this voice and accent. I just paused the video to comment this cuz this couldn't wait. Not to mention the explanation is excellent. Subscribed! ^_^

    • @Knowbee
      @Knowbee  6 ปีที่แล้ว +3

      Wow! This is one of my favorite comments. Thank you! Maybe I should be a radio announcer.

    • @SaiyaraLBS
      @SaiyaraLBS 6 ปีที่แล้ว +2

      Knowbee oh yeah! You should! You can also try doing audiobooks :D just let me/us(subscribers) know hahah cuz I'd love to listen!

  • @aftabyaseen7463
    @aftabyaseen7463 5 ปีที่แล้ว +16

    What a teaching methodology sir .... amazing sir.... i have no words 😶

  • @simondobbs4480
    @simondobbs4480 4 ปีที่แล้ว +3

    This is a masterful example of clear explanation. Bravo!

  • @lmthagod328
    @lmthagod328 ปีที่แล้ว

    This helped me understand mass spec in just an hour . I’m really greatful for this video

  • @dnarecording
    @dnarecording 5 หลายเดือนก่อน

    Hands down, best explanation of mass spec!!

  • @kayodeolaleye8103
    @kayodeolaleye8103 4 ปีที่แล้ว +4

    TOU'RE INDEED A WONDERFUL TEACHER. CONTINUE TO INCREASE IN KNOWLEDGE. THANKS A BUNCH

  • @RoysWanderlust
    @RoysWanderlust 7 ปีที่แล้ว +16

    Beautifully explained! Thank you so much for finally clearing all my confusions on MS!

  • @masumarahman2613
    @masumarahman2613 4 ปีที่แล้ว +1

    Finally, a worthy explanation.

  • @Jay-lq8ly
    @Jay-lq8ly ปีที่แล้ว

    Best video about mass spec ! So glad I found it

  • @safdarali8740
    @safdarali8740 6 ปีที่แล้ว +8

    I think its just enough for each and every student. tnx sir

  • @mabusurrahmansheikh6323
    @mabusurrahmansheikh6323 4 ปีที่แล้ว +4

    Does any change in molecular weight observe after forming molecular ion by knocking 1e away from it?

  • @rrw1418
    @rrw1418 4 ปีที่แล้ว +3

    It's really great to have teachers like you who genuinely make a best effort to explain lessons like this. Thank you so much sir . God bless you 🙏.

  • @rinkukumar-tk8jm
    @rinkukumar-tk8jm 2 ปีที่แล้ว +1

    Great way of elucidating complex concepts .Kudos.

  • @Bushravlogs15
    @Bushravlogs15 4 ปีที่แล้ว +2

    thank youuuu. So glad i found your channel,, I was floating in my online class today morning and its such a relief to have found this channel. Alhamdulilah

  • @nazaninerfany5910
    @nazaninerfany5910 2 ปีที่แล้ว

    Many many thanks, this video gave me a clear idea of MS. The explanation was so clear, informative, and simple.

  • @LeonEllisZ
    @LeonEllisZ 2 ปีที่แล้ว

    WOW WOW WOW! THANK YOU!
    It's so helpful when you break down the reasoning behind each thing. It helped me understand the fundamentals.

  • @PAMluvsLLAMAS
    @PAMluvsLLAMAS 3 ปีที่แล้ว +1

    THANK U SM FOR BREAKING THIS DOWN INTO EASIER TERMS !!

  • @Pkedya2boy
    @Pkedya2boy 6 ปีที่แล้ว +7

    Amazing lesson. Showing a very simple example after introducing the concept behind the method really helped my understanding. Really wish my teacher taught it in the same way!

  • @Alchemist_171
    @Alchemist_171 4 ปีที่แล้ว +3

    Couldn't think of a better, satisfying explanation. Why didn't I find this video before!

  • @shixiangxu6222
    @shixiangxu6222 ปีที่แล้ว

    I have a question. I think the m/z peak of 2-methylbutane at 72 should higher than pentane? why they are looking like the same in your slide. thank you

  • @curtpiazza1688
    @curtpiazza1688 3 ปีที่แล้ว

    Wow.....you have great teaching methods! I will remember
    remember the pool ball analogy....thanx!

  • @MonaMoawad
    @MonaMoawad ปีที่แล้ว

    From Egypt 🇪🇬 thank you very much

  • @husseinal-naeb2163
    @husseinal-naeb2163 ปีที่แล้ว

    When breaking the bond between c-c to the right, shouldnt the carboncation that is generated be CH3CH2+ with molecular weight of 29 g/mol ? Thank you

  • @nandhinimanjunath1236
    @nandhinimanjunath1236 ปีที่แล้ว

    A very understandable video under mass spec! Thank you.

  • @shafaanargya3599
    @shafaanargya3599 2 ปีที่แล้ว

    Thankyou sir, i was really stugle with MS fragmentation, this course really help me a lot!

  • @hansschetselaar1657
    @hansschetselaar1657 2 ปีที่แล้ว

    Wow!!👌👌👌very well explained about this topic🤗🤗Now I know more how to solve the ms graphs better👍 Always interested in it🤗Keep sharing

  • @Sbr_Shukr
    @Sbr_Shukr 4 ปีที่แล้ว +2

    Thanks alot ..made everything clear in so easy way.. thanks again

  • @xlBATES
    @xlBATES 6 ปีที่แล้ว +1

    Why is the 43g/mole peak approximately the same for pentane and 2-methylbutane? If you drop a CH2CH3 off of 2 methylbutane, the resulting charge is on a secondary carbon. If you drop a CH3CH2 off of pentane you get the resulting charge on a primary carbon. Am I missing something here?

  • @benalipozenezarinllen1668
    @benalipozenezarinllen1668 4 ปีที่แล้ว +1

    Very helpful video....thank you sir!!

  • @rbarta7446
    @rbarta7446 4 ปีที่แล้ว +3

    I am having an online class right now in ms, but God damn it, I just learnt more from the first 9 minutes of this video than in the whole semester...

  • @Deepakchauhan-ry6hs
    @Deepakchauhan-ry6hs 5 ปีที่แล้ว +5

    This was so beautifully explained, thankyou

  • @elizroma1
    @elizroma1 2 ปีที่แล้ว +2

    This was an amazing explanation! Thank you :)

  • @churrotaylor6534
    @churrotaylor6534 7 ปีที่แล้ว +3

    Thanks for the video. I am a little confused here. I think since we get more of a primary carbo cation than a secondary carbo cation, shouldn't the graph on the left side indicate that it is a primary carbo cation?

  • @with-jan-mohammad
    @with-jan-mohammad 2 ปีที่แล้ว

    Hey man you are a genius in explaining, hat's off

  • @jaisonissac4739
    @jaisonissac4739 8 หลายเดือนก่อน

    Fantastic explanation
    I was really confusing to learn mass spectroscopy
    U made it easy
    Can u please do all the A level topics in this way.
    Once again thankyou veey much sir😂😂😊😊😊😊❤❤❤❤

  • @yourfuturedocburenbeiya
    @yourfuturedocburenbeiya 4 ปีที่แล้ว +1

    This channel helped a lot; thank you SO MUCH sir!!

  • @fakhrulnawawi9681
    @fakhrulnawawi9681 7 ปีที่แล้ว +22

    there is a correction at 12.35..the carbon ( which hfragment of MW 28
    ) should have 2 H instead 1H

  • @fipacunha
    @fipacunha 6 ปีที่แล้ว +1

    In the last exercise, the peak at 27 is a secondary fragment ? Which means that the etil cation suffers another fragmentation loosing one hyrogen and resulting a fragment of 27 ? And in pentane, why is the 43 fragment the most abundant ? Pentane only gives primary carbocation ? Is this related to the number of carbons in the fragment generated justifying that the peak at 43 is greater than at 57 ?

  • @ThomasHaberkorn
    @ThomasHaberkorn 2 ปีที่แล้ว

    When the electron from the electron beam is hitting the molecule, where does this electron go after the collision?

  • @blissfuliska9866
    @blissfuliska9866 2 ปีที่แล้ว

    sir thank you very very much!! utterly grateful i found your channel sir!!🤩

  • @musemani1
    @musemani1 3 ปีที่แล้ว +1

    awesome explanation

  • @touhidislamTOUHID498
    @touhidislamTOUHID498 3 ปีที่แล้ว

    came to learn lc-ms. going with a degree in chemistry. hats off.

  • @saifurrahman3926
    @saifurrahman3926 2 ปีที่แล้ว

    best explanation. love from Bangladesh.

  • @marinedemaison9869
    @marinedemaison9869 6 ปีที่แล้ว +3

    thank you for your explanation it's very clear you explain very well

  • @ertanissever7047
    @ertanissever7047 3 ปีที่แล้ว +1

    For example in the problem the most abundant is 43 but in 43 there cannot be tertiary carbonation, so why tallest peak in 2 methyl butane????????? why is 43 tallest???

  • @animeshmukherhee7036
    @animeshmukherhee7036 7 ปีที่แล้ว +8

    The most best satisfactory explanation

  • @marissamarquez6461
    @marissamarquez6461 2 ปีที่แล้ว

    Great explanation. However, when I searched the mass spectrum of propane, it showed that the most abundant m/z ratio was 29. Could you explain that?

  • @291ayl
    @291ayl 2 ปีที่แล้ว

    Quick question,if you broke a hydrogen carbon bond and the hydrogen took both electrons becoming a hydride ion why wouldn't that be detected? Just because its an anion instead of a cation?

  • @vesarescue840
    @vesarescue840 5 ปีที่แล้ว +1

    Thank you! Great visual of whats going on.

  • @iceaureus
    @iceaureus 3 ปีที่แล้ว

    Easy yo know the mass spectrometer, thank you!

  • @黃捷欣
    @黃捷欣 2 ปีที่แล้ว

    I learnt a lot from the video! thank you so much!

  • @christabelnimako2618
    @christabelnimako2618 3 ปีที่แล้ว +1

    This is well explained, thanks Sir

  • @sundarakumarshanmugasundar1154
    @sundarakumarshanmugasundar1154 2 ปีที่แล้ว

    Great video!! Couldn't get any better

  • @mosab643
    @mosab643 5 ปีที่แล้ว +2

    How is the velocity measured?

  • @ibhadeerua1993
    @ibhadeerua1993 2 ปีที่แล้ว

    You are amazingly amaazing, thank you so much. God bless you

  • @FadeStrategy
    @FadeStrategy 6 ปีที่แล้ว +1

    Couldn't the 2-methylbutane lose its right hand side ch3 group turning it into an even more stable tertiary carbocation? @Knowbee

  • @phillwithskill1364
    @phillwithskill1364 4 ปีที่แล้ว

    Why wouldn't the CH3CH+ (MW= 28 g/mol) have a 2+ carbocation charge since the C is only bound to two other things?

  • @aamnailyas8246
    @aamnailyas8246 4 ปีที่แล้ว +2

    Thank youuuu so much! This has to be the best explanation of MS.

  • @dheerajkamath5776
    @dheerajkamath5776 5 ปีที่แล้ว +1

    Why doesnt carbocation rearrangement takes place?

  • @mr.shubhamroy3784
    @mr.shubhamroy3784 7 ปีที่แล้ว +2

    just awesome crystal clear concept thanks

  • @midtaylor-official9022
    @midtaylor-official9022 4 ปีที่แล้ว

    Excellent explanation ....absolutely understandable thanks 🙏

  • @annameadows739
    @annameadows739 4 ปีที่แล้ว +1

    Great video, thanks so much!

  • @homework..
    @homework.. 10 หลายเดือนก่อน

    What if we inject there 3
    Or 4 compounds?

  • @bottomtext251
    @bottomtext251 3 ปีที่แล้ว

    Nice job explaining the subject, I kinda missed the mention of Isotopes which would also be visible on the mass spectra.

  • @arexqui625
    @arexqui625 4 ปีที่แล้ว

    isn't there a possibility for the primary carbocation in pentane to rearrange?

  • @koksalan75
    @koksalan75 10 หลายเดือนก่อน

    What if the beam knocks out 2 electrons? Then what happens?

  • @amirhosein6053
    @amirhosein6053 ปีที่แล้ว

    Thanks
    It was dope sir❤❤❤

  • @IGISoftware
    @IGISoftware 4 ปีที่แล้ว

    Great video, is there material on your site explaining primary and secondary carbo-cations and what the difference is?

  • @khanmuhammad5149
    @khanmuhammad5149 3 ปีที่แล้ว

    Excellent ❤️👏🏻

  • @kreynolds1123
    @kreynolds1123 5 ปีที่แล้ว

    Question, Say your looking for relative isotopic difference between hydrogen and deuterium. Starting with a molecule it could be HH DH or DD. An electron gun could seperate a DH into D and H how can we identify the difference between HH and D? Or does then detector need to be sensitive enough to identify electron mass?

  • @jyothimalphonso829
    @jyothimalphonso829 2 ปีที่แล้ว

    Thank you Sir for such a wonderful explanation.

  • @yaseenwazir5844
    @yaseenwazir5844 5 ปีที่แล้ว +1

    Great job

  • @68-sarasultana54
    @68-sarasultana54 2 ปีที่แล้ว

    this one is really helpful. thank you

  • @Shivanikumari-sj8fz
    @Shivanikumari-sj8fz 4 ปีที่แล้ว +1

    I was so unable to understand the topic. The video comes as a blessing. Thank you !! ❤❤

  • @nishanidesoyza9784
    @nishanidesoyza9784 ปีที่แล้ว

    Could you please do a video series on HPLC .thank you

  • @chayangkulchinda1313
    @chayangkulchinda1313 5 ปีที่แล้ว +1

    thank you so much. super clear understand.

  • @brannigandupreez2083
    @brannigandupreez2083 11 หลายเดือนก่อน

    Wow, this is beautiful.

  • @peluvefinger
    @peluvefinger 7 ปีที่แล้ว +3

    thank you so much , this is taking a deeper explanation for me in this topic as im doing VCE

  • @ramden2002
    @ramden2002 4 ปีที่แล้ว

    Wow amazing explanation... Thanks a lot

  • @sauravkatuwal5122
    @sauravkatuwal5122 4 ปีที่แล้ว

    The best explanation🇳🇵

  • @joypalit6408
    @joypalit6408 ปีที่แล้ว

    11:51 shouldnt it be 29 gm/mole

  • @aba1usa
    @aba1usa 4 ปีที่แล้ว

    10 largest peaks in propane EI spectrum from NIST. 10 largest peaks:
    29 (999 ), 28 (587 ), 27 (419 ), 44 (274 ), 43 (231),
    39 (189 ), 41 (134 ), 26 (91 ), 15 (72 ), 42 (60 )
    Compare this with the spectrum given in the video.

  • @chemistryontipsbyvinitadex7467
    @chemistryontipsbyvinitadex7467 3 ปีที่แล้ว

    Nice explanation 👍

  • @gaazijavaid
    @gaazijavaid ปีที่แล้ว

    Very Nice. Excellent.

  • @alphagonist4748
    @alphagonist4748 4 ปีที่แล้ว

    Great great great great...amzing

  • @davidace7
    @davidace7 2 ปีที่แล้ว

    Beautiful explanation!

  • @zhaoxuema3771
    @zhaoxuema3771 6 ปีที่แล้ว +2

    excellent explanation.

  • @ciao_abhi
    @ciao_abhi 5 ปีที่แล้ว +1

    you are a lifesaver

  • @numanahmed9300
    @numanahmed9300 2 ปีที่แล้ว

    good video. thanks from Pakistan