MMR vaccine and COVID immunity
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- เผยแพร่เมื่อ 21 พ.ย. 2020
- Analysis of Measles-Mumps-Rubella (MMR) Titers of Recovered COVID-19 Patients
mbio.asm.org/content/11/6/e02...
The measles-mumps-rubella (MMR) vaccine
Theorized to provide protection against coronavirus disease
To determine whether any MMR IgG titers are inversely correlated with covid severity
Comparing MMR titers to recent COVID-19 severity levels.
The MMR II group
50 subjects who would primarily have MMR antibodies from the MMR II vaccine
Comparison group
30 subjects consisted of those who would primarily have MMR antibodies from sources other than MMR II
Including prior measles, mumps, and/or rubella illnesses
Results in the MMR group
Significant inverse correlation (rs = −0.71, P less than 0.001)
Between mumps virus titers and COVID-19 severity
Results in the comparison group
There were no significant correlations between mumps IgG titers and severity in the comparison group
Results in both groups
No correlation between between severity and measles or rubella titers in either group
Scale of the observation
Mumps titers of 134 to 300 arbitrary units (AU)/ml (n = 8), functionally immune or asymptomatic
Less than 134, (n=17) all had mild symptoms
Less than 75, (n=11) all had moderate symptoms
Less than 32, all who had been hospitalized and had required oxygen
Our results demonstrate that there is a significant inverse correlation between mumps titers from MMR II and COVID-19 severity
Four important points
Young children are largely spared from severe disease
Second, numerous countries have COVID-19 death rates that are as low as 1% of the death rates of other countries
Many people, despite prolonged close contact with someone who is COVID-19 positive, never test positive themselves
Nearly half of people who test positive for COVID-19 are asymptomatic
Mechanism of action
Sequence homology between both mumps and measles and rubella with SARS-CoV-2
After two doses
97% protected against measles
88% against mumps
97% against rubella
NHS site
www.nhs.uk/conditions/vaccina...
Born between 1970 and 1979, as you may have only been vaccinated against measles
Born between 1980 and 1990, as you may not be protected against mumps
Bradford Hill
Strength of association
Consistency
Reproducibility
Specificity
Temporality
Biological gradient, dose response
Plausibility
Coherence with lab findings
Experiment
Reversibility
Dr John, As an Australian epidemiologist specialising in International Health I really want to congratulate you on this wonderful public service. I watch you most days, while wishing I had teachers like you back in the day, and recognising your ability to present our field with such enthusiasm, and create high levels of interest even in lay people. You have made a significant contribution to the world 😀
what do you think about how Aus has handled this pandemic so far? Aside from some particular screw ups it seems we've done a really good job
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@@ratboys8689 I'm no doctor but it does seem Australia and NZ have been very successful so far especially over winter, other countries heading into winter don't seem to be doing so well.
Lol what’s his contribution to world , he is just reproducing what someone has written or researched .
@@nebhum GO AWAY, IF YOU” KNOW” so MUCH, what are you doing here in the first place? He saves people who ARE interested , from doing all the extra research he does for US,& explains so much more, to break it down for everyone,
I LOVE that he gets straight to the point in the beginning of the video to not clickbait anyone unlike typical TH-camrs 👏🏻👏🏻👏🏻👏🏻
Love "largely out of self-indulgence, because (it's) so interesting" talks!
Thanks again & always
You are my favorite person on the Internet! Thank you for educating us. I'm here since January and I'm never leaving!
I love these videos when John gets excited about something because we can see his brain ticking with excitement about something most people including myself can't see or know nothing about, but as usual he explains things in a way that helps people with no medical background understand what these experts are talking about! John you are saint my friend 😇😇😇😉👍
I think he says mumps in a cute way
Agree wholeheartedly! I’m one of “ the 3 or 4 “ who listened to the end! Thank you “ as always!” John.
He is a FRAUD
@@bennyboy4257 😂🤣👍😴😴😴😴
@@damianowens5066 take the vaccine,you won't last the day
I'm 80 and had mumps when I was a chhild. My acute covid was very mild
That's very good to know I seem to remember the mumps was one of the childhood diseases I had.
Jewel Levy I missed MMR but I think I had Mumps. What an amazing find.
@scott nyc in the UK when referring to illness acute means we get ill quickly, & recover completely in a matter of a few weeks or less, depending on the illness. Chronic means it drags on & on. sometimes for a life time with flare ups.
Thanks for the information, Jewel. My situation is identical to yours. I am 76, had mumps only, even though my brother had measles and I was deliberately exposed.
@scott nyc Acute is like "acute angle", something narrow. In medicine is something quick to go away. It is not a reference to severity at all.
This dude is bad ass. He had been way ahead of the WHO since January at least. You sir are awesome!!
Think how well this pandemic would've been handled with such people in the leading roles. Instead we have Dr's with ties to pharma, and useless politicians guiding the effort. 😔
Of course I watched your video until it finished! I can't get enough from you. You're so easily understood. I'm watching your past teaching videos now. Keep going! You're a breath of "fresh air"
Well I was one of the "3 or 4" still hanging on at 23:45. I imagine you underestimate how interesting your videos are Dr. John.
I think he left a few 0's off the end of the 3 or 4 "hanging on""
Without a doubt, so many stay until the end every of every video, informative and well explained every time. Thanks so much. Stay safe and well everyone 😷😊
He was being sarcastic.
me too
@@videoshomepage what makes you think that OP was being sarcastic ?
I allways stay till the end. Your work is simply worth it !
Myself also, we must be 2 of the 4 still watching. lol
@@glenchristensen3689 : There are at least another 3 of us in another thread. ^-^
Thank you Doctor Campbell. Always informative and no nonsense, but of course serious, compassionate, and even good humored where appropriate. You're a good man, and I'm sure a positive mentor to many.
I’ve never had the MMR vaccine, and now in my late 60’s, I’ve still never had mumps, even though I’ve been exposed several times. Neither my siblings nor my father have had the vaccine-or the mumps. Question: Has anyone studied the mumps titers in individuals who have never had mumps or MMR and a correlation with covid-19 severity?
that is what I was thinking. But as the good Doctor said - this needs more work to follow through these promising results. Having heard of older people in relatively poor health fighting off Covid, it would be interesting to look at their titres to this too - as well as pre-Covid infection and post Covid infection titres. Now IF your mumps titre went up post Covid ...........
Mumps is often asymptomatic. You might have had it without knowing.
People who've never had mumps shouldn't have any mumps titer at all so there would be no correlation to measure.
Your lucky because MMR vaccine that had the thimerosal in it was causing a inflammation of the gut and causing a infection, and the infection was leaking through the blood brain barrier and that is what caused crones disease and autism like ADD and ADHD in young kids back in the 70 I think, just by changing your diet in these kids there symptoms would get better.
I find it ironic Mercury and thimerosal was used back in them days and there were major side affects that parants were seeing but were covered up and now today with MRNA there using graphene oxide to cause the cell to be tricked and that is metal as well, are they poisoning us on purpose to create medicine for these symptoms?
I have had two booster MMR vaccines in the past two years. I'm grateful for this video.
Why did you have 2?
@@halo9lady It's common if your first one doesn't result in enough antibodies to give another.
I have 2 also
But not sure
Will it helpful for corona virus
I had a booster in 2018 and end of 2019. I got very sick about a month after my 2nd booster but havn't been sick since and havn't had covid
Fascinating, and potentially game changing. What immediately comes to my mind, is:
Are national and state health authorities aware of this study, and its implications?
The degree of precision and clarity you bring to these issues, is impressive. Thank you.
Yeah great isn't it, people won't take measles vaccine, you can't get mumps vaccine without measles included, mumps protects from covid( but only the vaccine not the actual infection,) two birds one stone.
Did you watch his episode where he called for a new world order?
@@kimberlyriddell8574 are you on about a video from way back where he was referring to a new world order meaning a different way of life compared to pre-Covid-19, he also then made a video apologising for saying nwo as he saw from the comments he realised the innocent mistake he’d made and apologised to all if he’d offended anyone or for anyone who thought he’d anything to do with the group that refers to themselves as the new world order. Does that clear things up for you?
I haven't had MMR vaccine and I'm going to skip all covid shots too.
These studies he sites have ridiculously low numbers and are therefore useless.
I'm 71 and live in Pennsylvania, USA. Tomorrow I'm going to try to get the MMR vaccine. If a prescription isn't needed, I'll go to one of the large pharmacies.
If a prescription is needed I'll have to go to my doctor who never seems think outside the box.
Dr. John Campbell, what an amazing find your the only one I trust to get info from, thankyou so much
Would also be a factor in why children are being spared from Covid!
Yes! I was one of the first cohorts to get the MMR - born in 1975. My older sister, born 1972 - didn't get it, and did get mumps as a child. So from my age down people may have this protection. Our GP also started calling people for a booster, when the pandemic was beginning but before lockdown. I wonder if they knew this was a possibility? We had been told that a booster would never be needed, but when I asked about that they said something about how the technologies change, and the diseases evolve, so now it#s worth doing.
@@debcurnock4202 and I as a nurse received it and others whose jobs required it so protection in older population will be hit and miss. Fortunately I take sufficient vitamins and common sense precautions and being retired have minimal exposure. My heart aches for the vulnerable forced to work high risk occupations and they are in my prayers daily, especially health care and their ancillary staff.
i was born in the US in july 1976, would i have gotten the MMR?
Yes possibly for some countries. A doctor in Spain had noted this and a larger study is being done. You can actually compare hospitalizations and deaths from countries that had strong MMR vaccination programs and those that did not.
Dr. Campbell you are going to seriously consider doing a "Part II" on this topic after you read all comments!
Ikr?? He opened up a whole can of worms here, lol.
He hardly ever reads comments or answers...
@@sunniva5335 mayb email him
I am one of the three still watching to the end. I found this one of the most interesting to watch in months. I am sure many would have watched this to the end. Brilliant stuff - as always!
I think he missed a few zeros after that 3 😉
@@andreesmith7051 He's a great teacher. So natural, just says what he thinks, oozes enthusiasm for the subject. Even the pauses when he forgets what he was about to say add to the interest. Much more interesting than the slick fast moving styles of those with over- reliance on editing. I always watch until the end, even when, in some of the earlier ones he seemed to me to be just accepting too much of the current wisdom and not questioning enough.
I'm one of the 3 (with missing zeros) as well. ^-^
Are you my niece ,( if so it’s auntie Megan)
I agree with the many.compliments on Dr. Campbell and his wonderfully informative videos. They (and Dr. Campbell) have been an invaluable resource during a very trying and frightening time. Oh, I always watch to the end.I love his teaching style. I have never had a teacher who so completely captured and held my attention.
Dear Dr. Campbell Thank you for your videos. I watch and listen to each and every one from beginning to end.
Very educational and there are always one or more kernels of knowledge to be found and are strangely re-assuring in these troubling times. Carry on!
I'm so glad you did this BRILLIANT extra video today!!!! Very critical information !!! THANK YOU!!!💜🙏
Really interesting and should definitely be explored further. Thank you for another sound video.
Thank you so much for continuing to keep us educated with valid data sources. Good educators are a critical resource to the community; they help lift all boats.
One of favorite subscriptions! So smart & interesting & charming too 🥰
Thank you for your fascinating presentation. I especially enjoy it when you explore and explain the science. Keep up the good work, please. I often tell people that I feel like I can keep up with the latest information and findings about the pandemic and disease because I follow you.
Thank you for your great way of making information so accessible to us lay people. We were having a family discussion on this exact topic on Wednesday evening , i find it fascinating.
Dr. John, this was one of the MOST interesting video/lectures yet that I've viewed on your channel. Thank you so much for all of your hard work. Regards
This is fascinating. Your videos have been helping me stay sane during the last few months. I recommend them to people often. Thank you.
still watching! This is your best one yet! Love you Dr. C
WOW!!! I wrote a comment (more of a question) about this about a month ago!!!! Amazing!!! Thank you for digging into this!
So did I, but then I heard no more about it, until now.
The first publication on this idea:- www.ncbi.nlm.nih.gov/pmc/articles/PMC7512551/n
Was two months ago on Sept 22, 2020
I think you have underestimated how clear your explanations are and how interesting you make your talks. I think you’ve missed a few zeros off from your 3-4 people listening to the end. Thank you very much for all the hard work you put into these presentations. I will continue to listen to the end.
Isn’t this what Ivor Cummings et al have been saying from the start , cross immunity exists throughout a large number of the populous already , up to 50% of the community has already a level of immunity to SARS CoV2.
I was one of those 3-4 people still watching at 23:39 :D
Jokes aside this is really interesting!
Thank you John
"Update" is probably the understatement of the century.
Next update suggestion would be the next Pandemic that the worldwide lock-down have created.. POVERTY and HUNGER. These grim reapers will take far more victims than the virus have ever done.
@@sergeant64 the problem was never not making enough food. Vertical farms will solve the production. The distribution and the willingness to make it fair and available for everyone will be the biggest hurdle, because human greed, what else.
@@iwanabana If done successful in Thailand vertical farming will *_knock-out_* 13 million Thai farmers. Which probably will leads to a military revolt and maybe a civil war.
I am one of your 3 to 4 viewers 🤔. Your show continues to help me understand the pandemic better than ALL the other’s combined. Thank You. John from Austin Texas.
I have been watching you from Australia since Feb
- you are a gem and a true gift to humanity during these uncertain times.
Many thanks.
We look at you in envy Australia
Dr John C , Im an example of an experimental group in the 1950s for TB Do we have anything to offer ?
I've had the MMR vaccines. They were required when I was a kid. This is very interesting!
Honestly, it should give you confidence, but doesn't call for going out to crowded pubs and dance halls.
I think vaccines wear out , you stop producing as many antibodies overtime, .
I had MMR I am resistant
@@wanderingpots This is probably why there is a spectrum of titers in the population.
@@jonthebru could you please let me know where the crowded pub is. I'd like to go.
Thank you Dr. Campbell, as always, you do a fantastic job at explaining these important and complex ideas .
This channel and the whole Covid saga is getting more interesting by the day, in a very positive way.
Thanks Dr Campbell much appreciated 👍
Very interesting Dr Campbell.
Most valuable insights.
Kind regards from the beautiful Chiltrens in Herts!
I’ve had measles and mumps in childhood and rubella in my early 20’s. Luckily no long term effect. Is there no protection to be had from natural infection at all?
Thank you again Dr John. You are a wonderful source of understandable information in a world of crazy statistics all seemingly conflicted. We trust you and are grateful for supporting us at this frightening time.
Vaguely remember that in the 80’s it was suggested that we needed a MMR booster vaccine, the hospital I worked for provided them for us nurses.
Yes I received one. I remember being a little anxious when I fell pregnant with my son only a few months later😳
@@annabizaro-doo-dah No probs though?
I got a free MMR booster shot in 1990 (my senior year of high school), thanks to a measles outbreak in my high school 😉
I had measles and rubella, but don't think I had mumps
@@brentboswell1294 me too!
My daughter's three housemates have all tested positive at various times yet she hasnt caught the virus from them despite pretty much living on top of each other. Wonder if this is anything to do with why.
Seems logical conclusion.
She's probably the one spreading it to them and is asymptomatic. By the time she gets tested after they are sick she's showing negative again.
@@prndownload Possibly. Thankfully they have all had very mild cases.
Could have all been false positives.
@@namispondjamispond9282 Only about 1.5 % chance that all 3 housemates had false positives ,if PCR test is about 75% specific in each case. But false postives are said to be even less than that , the order of a few percent ( 1-4 %) , so the chances of 3 false positives becomes a very small number indeed, a few 1/1000s of one percent. www.thelancet.com/journals/lanres/article/PIIS2213-2600(20)30453-7/fulltext
I watched until the end. You have become one of my very favorite beings! Thank you so much!
Your lecture today is as fascinating as it is hopeful. Thank you! You are a gifted Educationalist!
Fascinating! Great video! Kinda mind blowing
It is consistent with the fact that old people (not vaccinated with MMR) are more susceptible to COVID19.
Another piece of the puzzle.
Unless they had the diseases themselves.
Interesting thought. Hope they do more research.
@@ljo642 not necessarily. Bit like TB. Not everyone got it.
@@ljo642 I had mumps as a kid best part of 60 years ago, good chance the antibodies are still there but not as active or as strong as someone who's had the MMR vaccine + they'll be younger and fitter. MMR was first used sometime in the early 1970's I thinks ? Could also explain why the kids aren't hit as hard as the older generations being only a few years out from having the jab possibly.....? Wonder if we can get the jab at our age and if it'll do any good?
Most will have had the actual illnesses - may explain why some very elderly people are only getting mildly affected and are recovering quickly.
My husband and I listened all the way through...I am hopeful for this. Thank you.
Dr. John, to me is always wonderful watch your videos, no matter how difficult things are around here; I have the obligation to watch until the very last second. Nice week for you, Doctor!
It seems I am missing the mumps component from my vaccine :( interesting if a MMR will work for me now. Any suggestions?
I suggest you get the vaccine against COVID once it is available to you. MMR gives immunity to measles mumps and rubella. I’m sure Merck share price is doing well at the mo but this is what experts have to say about MMR/COvid study
www.sciencemediacentre.org/expert-reaction-to-study-looking-at-mmr-antibodies-and-covid-19-disease-severity/
I had measles, mumps, rubella and rosella over 60 years ago. I still showed antibodies when I was pregnant with my kids 37 years ago. Hopefully, I still have the antibodies.
@SD Illuminati Grand Founder 2 It's a bit homeopatic, isn't it?
I had all 3 diseases as a child, too.
I had to 're read your comment, thought you said you had 37 kids.... 🤔
@SD Illuminati Grand Founder 2 However, it was touched on that folks in sub-Saharan Africa were not being slammed by COVID, postulating that because they've been exposed to so many virulent diseases and have non-vaccinated antibodies that are protecting them. Again, the study here is merely correlative and not showing causation, but should lead to further study, I'd warrant.
Probably do I haven't caught the measles and I hang around with lots of unvaccinated kids who are occasionally getting measles.
Dr. Campbell, of course we are here! Thank you for this important information!
This is amazing John. Tha is so much for the work that you do and share!
That is awesome, I hope it gets to the main stream media.
I started looking into this a few months ago. Got my MMR in May 2018. Yay!
Even if I stand to get a lighter covid-19, I have chosed unpaid leave from my work, because I do not want to get and transmit.
@Steven L. I went to a travel medicine clinic at the time; try asking for it - adults need boosters
@Steven L. my University in Utah had me get them. It was two shots a few weeks apart.
Thank you. Always informative, clear and interesting. Staying to the end is always beneficial to understanding the ‘top line’.
Super interesting. Thank you, Dr. Campbell, as usual, your exploration is superb.
Thank you again for more great information!
this is very interesting, look forward to more research
Always staying until the end Dr C, you never know what little gems of information you might pick up. 😉👍☮️
Thank you for your research and post. I watched it to the end, like always. Thank you for your work . Stay healthy! Love from Russia
So interesting Dr John 😘 Thank you so much for sharing!
I watched til the end I find your talks so informative😊 ... Thank you for doing this👍
After listening to this video, I'm surprised you designate it as 'not for everyone.'
I think it's brilliantly insightful. Cross immunity, correlation, and causation are fundamental concepts.
Thank you!
Thank you John. Absolutely fascinating! I watched to the end!
Does the “if vaccinated before 1965(?) then one needs MMR booster” fit into this finding?
I think I would get a booster if born before 1965. I'm going to look into getting a booster. Can't hurt and might help!
Dr John, absolutely fascinating info. I simply had to watch to the end! 👍
This is amazing information! Your explanations are crystal clear and so appreciated. Thank you.
Amazing to hear you, as always Dr Campbell!
so this is why my doctor contacted me to come in for the MMR jab, just wish i had got it last year and not 9 months after getting covid
I got called in for my 2nd dose of the mmr jab, apparently you need two doses and I had only had one. I had the update jab in September, caught covid in October and it was very mild for me. Interesting update Dr John.
Dr john campbell is a FRAUD
You're right! This is really interesting!
Dr. John, What a great topic and so well explained. Like many others I watch almost daily and I have learned so much. Your depth and breadth of knowledge boggles the imagination. Love the paint can analogy.
Thank you, truly, for this. I watched the whole video. That really is a fascinating study; I hope we hear more about this topic.
These findings are so promising! I use screwdrivers as paint lid removers and jabbing at things too 😀
I wouldn’t like to be one of those parents who have refused to allow their children to have the Mmr vaccine.!
A fascinating programme tonight Dr J 👍 I think we will all be watching to the end 😁
I’m 32 never had mmr in my life had COVID never effected me bad was like a cold
Absolutely fascinating video. Your explanations are so understandable by lay people, like me. I am a daily watcher and appreciator of your time, expertise, and generosity. Thank you so much, Dr. Campbell.
Dr john I'm so pleased you covered this. As this was my theory way back from April last year. Being a mother and grandmother I started to reserch so much into children having less infection. My family all thought I was just babbling on. Thankyou so much x
Very interesting and quite a find I feel I did not have MMR as 66 years old could the BCG Jab give protection
I had mumps quite severe if I remember correctly
I have not had measles but have had shingles ??
Shingles is caused by the varicella (chickenpox) virus left over in the body from a prior infection and it's unrelated to measles.
Interestingly, repeated exposures to the varicella virus over the course of one's life is protective against shingles.
Growing up in an Eastern European country in the early 90s, I only got the measles vaccine and have gone all the other childhood illnesses, such as mumps, rubella and chickenpox.
@@luizaplesca8226
Agreed. I have had chicken pox and so have my children. I have not had shingles.
@@snowbird6855 maybe if you got shingles, you’d understand the value of vaccines 😊
Thank you!!! Dr John very informative as usual.
Thanks Dr Jon, Still find your videos fascinating, Thank you for your time :)
John, you are a legend! Love watching these, my inner geek and outer biology teacher is very happy :) Thanks, keep them coming :)
Has anyone asked . Does Sweden give it's older population a mumps booster.
Aha! Finally a worthwhile comment.
You are thoughtful type.
👍
So I'm a bit confused! My father had the mumps when he was little (hes 75 now) so would he be less likely to get severe symptoms from covid because of those antibodies. Or is it only less severe symptoms for those who are producing antibodies from the combined MMR vaccine??
Only with MMR vaccine is there protection
@@newnewsbrooklyn1513 thanks Brooklyn!
This is maybe your best video yet! Truly fascinating and another brilliant master class on how to explain complex science to a brad audience. You even mentioned Oral Rehydration salts, a recipe and story I tell all my physiology pre-med students. Thank you for your work and for making me a better teacher.
Thank you for your dedication and brining new research possibilities to light.
This is a fascinating video. It a pity that I am of an age not to have received the MMR vaccine so am more likely to get a severe dose of Covid. I also never had mumps so my body has no antibodies against it. Depressing really. Thanks as always for keeping us updated.
Go get the MMR jab now pronto. If news spread MMR vaccines may very soon be as scarce as hens teeth. Now lady please.
Many thanks for vid DR really enjoyed: )
Please contact your family doctor
Wow, amazing stuff, the studies that are done are truly remarkable, my son had mmr but not my daughter, I am definitely too old, lol. You made it very easy to follow, thoroughly enjoyed it x
Another informative and interesting video from start to finish. Thank you Dr. Campbell.
So instead of the new Covid vaccine we could just give people MMR boosters.
i doubt it...bill gates n fauci are heavily vested in vaccines so they will insist everyone get jabbed despite the results...dont forget BG is a eugenist...
Why not both?
@@nighttrain438 that would invalidate the emergency use classification of the Jim Jones shots.
This is an incredible find;
I read about MMR and covid a couple of months ago. It was only a theory then.
@simon temple nothing proven on vitamin D.
@@Justlookin958 of course there is its well documented
@@Justlookin958 enough correlation out there for me!
@schlaberdasken "Can cod liver oil prevent Covid-19?" What, from the worlds largest producer of Cod Liver Oil? Coincidence I am sure. :- "The chief countries producing cod-liver oil are Norway, Japan" oh, and Iceland.
Very interesting and intriguing. Watched every second! Thanks
Thank you Dr Campbell, thank you for your service throughout the epidemic , that you provide knowledge easy to understand.
I always watch till the end
My covid symptoms where reminiscent of the mumps i had as a child, very interesting
Your cheeks swelled up from COVID-19? That's not a symptom I have heard before.
@@randmorf Yes, I never heard of that also until my brother caught it & the entire left side of his face was swollen terribly. They initially thought he had a salivary stone, but ended up testing positive for Covid.
Very interesting J C! Love the way you explain the experts findings and with your experience make it more clear!
Thanks! My real thoughts are! Your experience far exceeds the so called experts! Just common sense really!
So interesting and can’t wait to hear more! Thank you Dr. John!