As for Metoclopramide, it is also said to block 5HT3 receptors to some degree (antagonist). Interestingly, the mentioned increased gastrointestinal motility is initiated through the stimulation of 5HT4 receptors (agonist), which lead to a release of acetylcholine. Very good video, thank you!
The cause of motion sickness is not limited solely to the inner ear. It's because the different organs which we use to determine our position in space (inner ear, eye and cerebellum) sometimes send incompatible information to higher centers, resulting in nausea. That's why sitting in the front of the vehicle helps with motion sickness - because then we see the road moving in front of us, which is more in line what our vestibule and cerebellum pick up on.
I've experienced hyperemesis with all my pregnancies, currently my 3rd pregnancy and this was surprisingly the 1st time antiemetic medication helped at all.
*Chlorpromazine 😊 Thank you for making concepts easier, making me understand things I couldn't quite understand from my books ❤️ right when finals are around the corner 😂
Obey Jesus Christ or you will go to hell, turn to the Lord before its too late, if you don’t REPENT OF YOUR SINS then you will likewise perish in hell. All liars, fornicators, adulterers, idolaters, blasphemers, whoremongers, thieves, murderers, homosexuals, effeminate, etc, will not inherit the kingdom of God. Once you turn to the Lord, read the new testament in the bible, the gospels, to develop a relationship with God. God bless you all. Turn to Jesus, repent or perish, turn or burn.
Would love a updated video that includes Neurokinin-1 Receptor antagonists (Substance P antagonists) like aprepitant, fosaprepitant, netupitant, etc. Great video!
Fascinating. Our own bodies produce an effective anti-emetic, from one of those glands in the neck area. You can test it out by taking little sips of something that really "doesn't agree with you". When your body tells you either to stop or to throw up, ignore it and carry on. You'll feel something flow into the back of your throat which will quell your need to vomit. It has quite a distinctive taste, which I can't really describe, but pleasant. I understand it's a very functional thing for other species, though it rarely comes into play for us. Have a bucket handy if you try this experiment.
You probably should've mentioned this small detail regarding the medulla oblangata since it's pretty high yield: not only does it contain the vomiting center, it is also the reason why alligators are ornery (despite what mama says).
in the vomiting center, there are other several receptors like serotonin receptor cause if the vagus nerve transiting the serotonin signals it makes sense that it is only can attach to serotonin receptors but overall this was an amazing video thanks so much for your hard work
Hi Armando; amazing video thank you. I am an advanced practice paramedic in the UK currently doing a prescribing course and this was really helpful. Maybe a little more info on the pharmacokinetics e.g. absorption, elimination and half life etc would have been extra amazing too...although I get that this is not where you were pitching this. Thanks and keep them coming.
coming from an emetophobe, I can say with confidence that vomiting is, in fact, voluntary. I've been motion sick millions of times, have had food poisoning and norovirus amongst other forms of gastritis... as well as a concussion..and haven't puked since 2005 ;) xo
Savannah Whitacre I am the exact same as you Savannah. I have been emetophobic my whole life and I haven’t vomitted in years. I have used medications like ondansetron to stop vomitting. I have felt nauseous but never vomitted.
Excellent lecture! Never saw anyone make barfing look so fascinating and artistic! I'm serious. If you can do that for this topic, you can do it for anything,. Fantastic job 🙂.
Thank you so much for this video. We were just taught this topic in class, I forgot to bring along my book to review, so I was super happy to see this uploaded, helped alot.
you are a guru mehn...i can kiss u a billion times...u just made my day! make more videos on any health conditions and pharmacological approach...thanks a lot!
Thank you so much sir....plz make videos o chemo bcz it is very difficult to understand and remember..... I hav tried a lot of ways but no use......so plz plz plz
video is really nice. but please give the mechanism of action of prokinetic drugs like metoclopramide , dompirodone. u gave details about CNS effect hw it acts on g.i. please elaborate.
🧠 TEST YOUR KNOWLEDGE FROM THIS LECTURE! ✅
youmakr.ai/test-playground/questionnaire/673d3d72859b9c170836ed53
As for Metoclopramide, it is also said to block 5HT3 receptors to some degree (antagonist). Interestingly, the mentioned increased gastrointestinal motility is initiated through the stimulation of 5HT4 receptors (agonist), which lead to a release of acetylcholine.
Very good video, thank you!
The cause of motion sickness is not limited solely to the inner ear. It's because the different organs which we use to determine our position in space (inner ear, eye and cerebellum) sometimes send incompatible information to higher centers, resulting in nausea. That's why sitting in the front of the vehicle helps with motion sickness - because then we see the road moving in front of us, which is more in line what our vestibule and cerebellum pick up on.
Make more videos on pharmacology please...it will be helpful.
😂
Which year now sir or what you are doing now
I
Mo
I am 27 and a stroke survivor I find your videos extremely helpful. I have ataxia. I find that when I
bro got stroke in the middle
@@naveedmemon4055oh my word and we still haven't heard from them! 😢
I've experienced hyperemesis with all my pregnancies, currently my 3rd pregnancy and this was surprisingly the 1st time antiemetic medication helped at all.
I will have my Oral revalida next week and this video makes it easier for me to remember all about antiemetics.
*Chlorpromazine 😊 Thank you for making concepts easier, making me understand things I couldn't quite understand from my books ❤️ right when finals are around the corner 😂
Obey Jesus Christ or you will go to hell, turn to the Lord before its too late, if you don’t REPENT OF YOUR SINS then you will likewise perish in hell. All liars, fornicators, adulterers, idolaters, blasphemers, whoremongers, thieves, murderers, homosexuals, effeminate, etc, will not inherit the kingdom of God. Once you turn to the Lord, read the new testament in the bible, the gospels, to develop a relationship with God. God bless you all. Turn to Jesus, repent or perish, turn or burn.
You are such a life saving angle. Keep up the good work sir
Would love a updated video that includes Neurokinin-1 Receptor antagonists (Substance P antagonists) like aprepitant, fosaprepitant, netupitant, etc. Great video!
Fascinating. Our own bodies produce an effective anti-emetic, from one of those glands in the neck area. You can test it out by taking little sips of something that really "doesn't agree with you". When your body tells you either to stop or to throw up, ignore it and carry on. You'll feel something flow into the back of your throat which will quell your need to vomit. It has quite a distinctive taste, which I can't really describe, but pleasant. I understand it's a very functional thing for other species, though it rarely comes into play for us.
Have a bucket handy if you try this experiment.
Sir ,you are a very good teacher.
i love to learn !! best feeling in the world, and it's free!!!!
Yes!!!
We need an antibiotics video next! 😁
Already done my friend.
th-cam.com/video/IVBCrzjOl40/w-d-xo.html
Afiq Syahmi uiii
never understood antiemetics and vomiting so well before! thanks
You probably should've mentioned this small detail regarding the medulla oblangata since it's pretty high yield: not only does it contain the vomiting center, it is also the reason why alligators are ornery (despite what mama says).
in the vomiting center, there are other several receptors like serotonin receptor cause if the vagus nerve transiting the serotonin signals it makes sense that it is only can attach to serotonin receptors but overall this was an amazing video thanks so much for your hard work
Hi Armando; amazing video thank you. I am an advanced practice paramedic in the UK currently doing a prescribing course and this was really helpful. Maybe a little more info on the pharmacokinetics e.g. absorption, elimination and half life etc would have been extra amazing too...although I get that this is not where you were pitching this. Thanks and keep them coming.
ahhh pathopysiology plus pharmacology
best video ever made
Absolutely love the explanation of N/V. Straight to the point.Thank you.
Thank you....when i saw my textbook, it was looking so confusing, now it has become easier..💜
Thank u very much for ur help sir. This is very important .
Thanks again. ❤
From Srilanka 🇱🇰
coming from an emetophobe, I can say with confidence that vomiting is, in fact, voluntary. I've been motion sick millions of times, have had food poisoning and norovirus amongst other forms of gastritis... as well as a concussion..and haven't puked since 2005 ;) xo
Savannah Whitacre I am the exact same as you Savannah. I have been emetophobic my whole life and I haven’t vomitted in years. I have used medications like ondansetron to stop vomitting. I have felt nauseous but never vomitted.
@@kimberleywilliams5199 is ondansetrone better than metoclopramide
amazing illustration and explanation. keep up the great work!
جزاك الله خيراً 🤲
better explain and classify antiemetics drugs here than lippincot
you nailed it
Pronunciation may differ..BT explanation was grt sir..thank uh sir🙏
Great video 👍very helpful
Excellent lecture! Never saw anyone make barfing look so fascinating and artistic! I'm serious. If you can do that for this topic, you can do it for anything,. Fantastic job 🙂.
You are king 👑 of pharmacology
This was nice and was pretty much just like what's in my notes, so thank you!
Man u r Just genius...
That's only i can i say u...
Thank you so much for this video. We were just taught this topic in class, I forgot to bring along my book to review, so I was super happy to see this uploaded, helped alot.
It is so helpful....and make concept much clear...thank you sir
Great video. This was perfectly designed and executed.
I think the vestibular apparatus doesn't go through the CTZ but via the cerebellum and activates the Vomiting Center
Great! U should put the whole pic at the end so we can capture it pllzzzzzz
You’re amazing sir , love your diagrammatic explanation ❤️❤️
i read it as antimemetics and didint expect this.
thank you for this, I know understand the physiology of emesis and the basic pharmacology of anti-emetic drugs. 😊⭐
Thank you so much you make med school survival seem so easy 😍
thank you for this great video. It is covered a lot in the short time
The best video for nursing students. just wondering the physiology of self induced vomiting
Thank you very much
amazing teaching way
Awesome explanation. Thank you
Bro.. am a huge fan for you.. please explain pharmacology of antileprotic drugs
U r the best. U cleared all my doubts
Amazingly explained!! You are doing a superb job👏🏻👏🏻
Amazing experience sir but we need more videos
Marvellous effort Sir !! Keep it up ... My many concepts are clear now ..
My inquisitive approach nto knowledge send me over here...very informative
you are a guru mehn...i can kiss u a billion times...u just made my day! make more videos on any health conditions and pharmacological approach...thanks a lot!
So good, you should give more examples drug, thankyou
Amazingly explained 💯
Thank you sir ...🙏🙏🙏
Amazing video .. ❤❤❤
Thank you 🙏🏻 ❤
Where can i find this paper complete as it's a good summary?
❤️
Thanks!
Excellent!
You have lovely ability! Thank you so much
Thank you
Thank alot sir for all the videos you made cology so easy and Interesting... 😇
Great explained....great job sir
I think, it is a hyoscine instead of ayoscine. Great video anyway. Thanks :)
amuhaimin _ He says this in the video but wrote the class down.
Ur videos are very clear tnx 🤩
i hope he covers morning sickness
Please do make a video on laxatives....Love your videos...very helpful...thank you
you are brilliant.....
Thankyoou so much Armando , you are the best teacher (Y)
Very educating
elaborative
Thanks , you are a great
Very helpful thanks ❤
Thank youuu very much
Can you add the summery part at end of the video ?
thanks for this short lecture 😎🙌
You are amaaaaaaaaaaaaaazing !!! Thanks from the bottom of my heart, you really helped me a lot with this useful video
Take it, take the vomiting centre out of me, please! Haha
Great video
Well understood
please make video on anti diarrheal drugs and laxatives complete, thanks
Very good
Thank you!
Skolo bafethu yooo ha.a fok man, dankie ngwanesu
Thank you so much sir....plz make videos o chemo bcz it is very difficult to understand and remember..... I hav tried a lot of ways but no use......so plz plz plz
So helpful...thank you
This video helped me so much ! Thanks alot :D Please can you make a video about Anti-anaemia and Haematinics!
thanks
Sir your best
Great job thanks so much
Fantastic
thank you so much it's really helpfull
Its soo good 😇thank you
Thank you so much for making this wonderful video ...it is really helpful 🌺
amazing video, thank you
Great work thanks
Your information is very important, please ..can you traslate all videos ,witn cc, in spanish, hug from Colombia..
.
video is really nice. but please give the mechanism of action of prokinetic drugs like metoclopramide , dompirodone. u gave details about CNS effect hw it acts on g.i. please elaborate.
Great video........ Thnk u so much.......
Thanks for Great video