For those who would like some details on the formation of chylomicrons:once inside the enterocytes via passive diffusion ,lipid components(FAs,Ch and MGs) are transferred to the smooth ER after binding to cytosolic fatty acid-binding proteins.There,enzymes catalyse the re-esterification reactions(ACAT for Cholesterol,MGAT for MGs etc).Then the esterified lipid components are packaged into chylomicrons with the help of Microsomal Triglyceride Transfer Protein(MTP) which stabilises the hydrophobic center and ApoB-48 which stabilises the the lipid monolayer surface.Further processing occurs in the Golgi Apparatus,before the newly formed chylomicron exits the basolateral membrane and enters the lymphatic system.
@@jamesgordon8867 been using that 3 years ago before the channel even became popular. I just told my one friend to keep it a secret and suddenly everybody was using Ninja nerd videos the following year lmao
You got a real education. More than I ever got. Look at Chromium. Diabetes, LDL& fatigue. Your patients need your expertise. So glad you get real medical education
Don't understand why we pay so much tuition for "review it on your own" type "lectures" in medical school when a youtube video explains it 800 times better with more clarity.
This whole Biochemistry playlist is amazing. A great resource for RDN students. I retained more by watching your videos and applying the mnemonics than by reading my textbook. After watching your videos my advanced nutrition notes suddenly made sense. And I passed my final with a high-grade today. Thank you!
ILY DirtyMedicine!! As a student who's even struggling just to pass step 1, your videos have been such a lifesaver in teaching me foundational concepts I didn't have/forgot...fingers crossed I get to that pass, but I can't thank you enough. I don't know what I'd do w/o your videos
Omg, this was a fantastic way to break it down. And the mnemonics for lipid transports are way too good. I've written all of them down on my First Aid.
I am really thank ful to you really I tried many resources I couldn’t get anything out of them I wished I would’ve known about you before in my medical school you’re the best ❤
Thanks for 2:43 long motivational intro. If you take a hobby of songwriting, you’ll be able to put that 2:40 into 0:40. …but now, I dive to wonderfull world of lipids and metabolism… Happy holidays!
Dirty: "If I put all this stuff into one video, you'll go home crying and that's not my goal." Med School Professors upon hearing this: "We need to "eliminate" dirty asap!! 😠😠😠"
I am not a medical student. I am a retired 63 year old guy, but I know that the liver sends bile salts to the gallbladder and cholecystokinin is released into the small intestine (duodenum) to trigger contraction of the gallbladder. Thus, releasing bile salts. cholecystokinin and secretin reduce pH allowing better emulsion of the fats, freeing them up for pancreatic lipase to do its work. The monoglycerides and fatty acids do not just reassemble in the enterocytes, the smooth endoplasmic reticulum reforms the monoglycerides and fatty acids into triglycerides. I hope medical students learn more than I know before graduation.
Thank you 🙏 Thank you 🙏 soooo very much for the shortest and best way of explanation I really understand all the process and learned! I wish I could contacted you to get more support. if I pass the exam I will donate a good amount for your valuable program You deserve it
So I think this is obvious but the reason we have to break down fats, build them into triglycerides break them down again and build them into triglycerides again for storage is because of the difficulty of transferring fats throughout the body? It just seems like an inefficient system ....
I have a question so if all those steps are important what would you say happen if you eliminate the pancreas and where does the bile and fat dropplets get broken down?
hi dirty thank you for all the videos. I wonder if it is possible to integrate this video to lipid lowering drugs? because drugs are also highly tested. could you make a video about lipid lowering drugs as well? thank you so much!
For those who would like some details on the formation of chylomicrons:once inside the enterocytes via passive diffusion ,lipid components(FAs,Ch and MGs) are transferred to the smooth ER after binding to cytosolic fatty acid-binding proteins.There,enzymes catalyse the re-esterification reactions(ACAT for Cholesterol,MGAT for MGs etc).Then the esterified lipid components are packaged into chylomicrons with the help of Microsomal Triglyceride Transfer Protein(MTP) which stabilises the hydrophobic center and ApoB-48 which stabilises the the lipid monolayer surface.Further processing occurs in the Golgi Apparatus,before the newly formed chylomicron exits the basolateral membrane and enters the lymphatic system.
video starts at 4:17
Thanks
Yeah, but you miss at least three good and relatable jokes. Laughing + Learning = the best way to learn IMO
Lots of pre-amble and pre-pre-amble talking about what he’s gonna talk about instead of just getting on with it
I think it starts al 00:00
@@rob28803 yeah and?
I just got into medical school today. You're gonna be my friend for the rest of the semester especially in Biochem! ❤
BFFs!!!!!
You need Ninja Nerd too
@@jamesgordon8867 been using that 3 years ago before the channel even became popular. I just told my one friend to keep it a secret and suddenly everybody was using Ninja nerd videos the following year lmao
You got a real education. More than I ever got. Look at Chromium. Diabetes, LDL& fatigue. Your patients need your expertise. So glad you get real medical education
Great way for patients to better understand: lab values, better patient compliance
20 vids in the past 24 hours. Don't wear yourself out, Dr. Dirty ;)
Don't understand why we pay so much tuition for "review it on your own" type "lectures" in medical school when a youtube video explains it 800 times better with more clarity.
totally agree!!
TH-cam does not give you the diploma
Absolutely
Self-directed learning?
Androgogy?
Critical analysis?
Critical thinking?
This whole Biochemistry playlist is amazing. A great resource for RDN students. I retained more by watching your videos and applying the mnemonics than by reading my textbook. After watching your videos my advanced nutrition notes suddenly made sense. And I passed my final with a high-grade today. Thank you!
I regret you tube has only one like button.
Thank you so much for your work
Your dirty lectures are understandable and easier to memorise than school lectures. That is undeniably true.
ILY DirtyMedicine!! As a student who's even struggling just to pass step 1, your videos have been such a lifesaver in teaching me foundational concepts I didn't have/forgot...fingers crossed I get to that pass, but I can't thank you enough. I don't know what I'd do w/o your videos
Hey! Did you end up passing? Currently in this boat too :’)
@@santoshaveeramachaneni7615 I wanna know too
Man you're a life saver. Your videos are helping my board prep out so much! thank you!
I can't thank you enough. You are so wonderful. you save me for my step 1.
THANK YOU THANK YOU THANK YOU!!! Big HUGS and major gratitude!
"one of those people" sent me lmaooo
keeping learning light and fun life saver
U really suit me bro. Your type of explaining thing really suits my learning process. Keep the good work.
Same
Just a layman person interested in health and biochemistry. This is amazing.
I'm sorry...but did you just upload a ton of Biochem videos, which is something I'm absolute shit at? Is this Christmas?
Thank you! Your method of explaining this is so easy to follow!
Best ever. An amazing educational videos. Simple, straightforward and seeded happily in our memories
not a med student, but a vet student. I think this was a great way of explaining this material
You are a TRUE TEACHER.AMAZING!!!!
When I start getting my paycheck. I ll definitely give this patreon some good dollars
Starts at 3:39
Omg, this was a fantastic way to break it down. And the mnemonics for lipid transports are way too good. I've written all of them down on my First Aid.
I have a test tomorrow 😊you just saved my life
I am really thank ful to you really I tried many resources I couldn’t get anything out of them I wished I would’ve known about you before in my medical school you’re the best ❤
Dr. Dirty ...u are a saver ..man...really ,the topic which was diffficult for me ,u really explained me that ..thanks
Thanks for 2:43 long motivational intro. If you take a hobby of songwriting, you’ll be able to put that 2:40 into 0:40.
…but now, I dive to wonderfull world of lipids and metabolism…
Happy holidays!
Dirty: "If I put all this stuff into one video, you'll go home crying and that's not my goal."
Med School Professors upon hearing this: "We need to "eliminate" dirty asap!! 😠😠😠"
haha funny! 🤣
Very helpful for medical biochemistry!! Thank you!
Marry us! We love you hahhaaha love your videos, the Best teaching ever
…if you’re… one of THOSE people.😂
Forever grateful to your videos sir once I start earning I am gonna donate for sure
Best explanation ever! thx
I am not a medical student. I am a retired 63 year old guy, but I know that the liver sends bile salts to the gallbladder and cholecystokinin is released into the small intestine (duodenum) to trigger contraction of the gallbladder. Thus, releasing bile salts. cholecystokinin and secretin reduce pH allowing better emulsion of the fats, freeing them up for pancreatic lipase to do its work. The monoglycerides and fatty acids do not just reassemble in the enterocytes, the smooth endoplasmic reticulum reforms the monoglycerides and fatty acids into triglycerides.
I hope medical students learn more than I know before graduation.
Bro you are a true life saver
keep it up!
Dirty, you are amazing!
awesome new set of videos! we would love it if you make a video on Lymphomas!!
Explanation starts at 3:35
Thank you 🙏 Thank you 🙏 soooo very much for the shortest and best way of explanation
I really understand all the process and learned! I wish I could contacted you to get more support. if I pass the exam I will donate a good amount for your valuable program
You deserve it
you are so right!! no one talks about lipid transport!!!
Ezekiel bread and avocado! Only someone who eats that would know the name. lol
This is exactly what I was looking for! Thanks. My textbook made it so complicated.
OMG, you're so awesome, thank for you job
Hi Russia
first viewer
thanks for the nice explanation
Ur jst awesome...exactly as u said I was lost in the lipid metabolism after seeing many videos...but u made all clear...thanx alot n keep it up..😍
You are a life saviour
You are amazing thank you ❤❤
So I think this is obvious but the reason we have to break down fats, build them into triglycerides break them down again and build them into triglycerides again for storage is because of the difficulty of transferring fats throughout the body? It just seems like an inefficient system ....
Thank you 😊 💓
The best♥️♥️♥️♥️♥️♥️♥️♥️
thanks for your great videos！
Thank you so much for this video!
Thank you so much for your hard work for us
5:20 breakdown products
Thank youuuuuu finallyyyy.
A M A Z I N G! Thnx for :’) God bless You
I have a question so if all those steps are important what would you say happen if you eliminate the pancreas and where does the bile and fat dropplets get broken down?
complex question but briefly this is what happens when people have decreased ability to metabolize fats. this is the classic fatty greasy stools, etc.
I was definitely sleeping those biochem lectures...
Please post the ethics video again
How we will get pathoma dr Satra videos.. does its necessary to clear our concepts. Does any others free resources for pathology.
Thank you
You are the best
hi dirty thank you for all the videos.
I wonder if it is possible to integrate this video to lipid lowering drugs?
because drugs are also highly tested.
could you make a video about lipid lowering drugs as well?
thank you so much!
*Summary is from: **12:07** onwards*
Is Harper text book is one of your referrences? Like what is your major referrence?
Thanks
Thanks!
Helpful video ❤
thank you so much for making this video
I LOVE U!
Fantastic!
Awesome .. thanks ..
Everything goes over my head
Thank you very much
Trust me, I have had enough Ls in medical school career so far
4:15 Start..
What happens to cholesterol?
Good question
Here I am as a cardiology fellow watching this video and homie is talking about USMLE lol
Lemme here a whatttt! If you’re using this in 2021
lol I am not a med student and I need to know all of this stuff and more for nutrition
The channel with right amount of dirty.
They’re smart? They made it all the way down...despite...digestion?
Wow
Wanderful
Help me dirty medicine, you are only my hope.
LOL.
*from biochemisty student, IPB University, Indonesia.
❤❤❤❤❤❤
You go home crying 😂😂
Te amo Sucio!!!!
hahahahaha xd
lipsitis that got me laughing my ass off
👍
i love you
At 4 minutes you start!
just got in love with u❤
vedio starts after 5 min
This video is not high-yeld
Great videos but god damn u repeat the same things over and over and over again.
It's to help memorize the content. If you'd prefer stuff where its one and done go read a textbook
Dirty Medicine it’s ur specialty dude..keep repeating it is so much helpful Thank you I am ur fan 🙏
thanks