Lipid Lowering Agents (Cholesterol Drugs)

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My goal is to reduce educational disparities by making education FREE.
These videos help you score extra points on medical school exams (USMLE, COMLEX, etc.)
For educational purposes only; NOT medical or other advice.
Some videos contain mild profanity and hyperbole solely used to assist with memorization. Viewer discretion advised.
Opinions are entirely my own.

[@madinaradjabova1668]

HM*G (good for) *CO A (coronary artery)

[@rachael4775]

this is literally the most brilliant little trick ever my jaw is on the floor hahha

[@ruzan6386]

Genius. Will never forget this

[@TheRyanChang]

for PCSK9 inhibitors
Pesky (PCSK-9) muhammad ali (ALIrocumab) Evolved (EVOlocumab) boxing.
This also helps us remember the side effects because you have NEURO effects and soreness (mylagias) from boxing

[@nehadharap700]

ahhh,THANKS DUDE!

[@ruzan6386]

Thank you!

[@erikramos1972]

Dirty, you are that guy. Thank you for contributing to all of our success!! You are a great teacher and great person in general!

[@justaryana]

Dirty, you did it again. you really did do a better job teaching this than ANYONE else. and in the nick of time for my exam!

[@hehateme1187]

To remember the ↓ LDL exceptions, Fibrates and Niacin, I added this little mnemonic:
fibra↓Tes (↓ TG) and "Nancy is extra Hot!" (Niacin - ↑ HDL - flushing)
For remembering the majority decrease LDL, I remember "All the fatties drop it LOW LOW" (Lipidemia drugs ↓ LDL lol)

[@user-eb3ni4bz9q]

Dude, you're like a magical teacher that I go to when ever I stuck in a subject.

[@doom_inik]

exam in 10 days, coming in clutch with this topic cause first aid had a lot going on with those visuals (same with sketchypharm), but you made this v easy to follow👍

[@yashpawate1306]

Perfect time for my pharm test tomorrow. Thank you so much!

[@tesnimhamdan5813]

My exam is in 2 months and your videos are so essential during this period. You just simplify everything, especially pharma which is so hard to memorize. I watched your video on HIV drugs and I answered the UW questions like it was nothing. Now I guess the lipid lowering agents will be a piece of cake as well. Thank you so much!

[@palomiichimplin2855]

Thank you so much for your support 🇪🇸👏🏽👏🏽👏🏽

[@uswahsiddiqi238]

Thank you so much! Will definitely support via membership once I start earning! THANK YOU

[@yummy1857]

It’s a measure of how interesting your videos are when I’m watching them on my break after exams lol

[@sanjananayak4348]

Thank you so much! You have no idea how much anxiety this topic gave me before this video.

[@GabrielSantAnaCarrijo]

In portuguese they translated "Bile acid resins" to "Bile acid kidnappers" which is just 1000% better

[@hivalee6992]

might be your best video

[@fireman00742]

Dirty medicine is by far my favorite learning tool. I have not purchased a text book in my FNP program yet. Thank you !!!

[@georgiabessie]

How’s school going? I’m in year two FNP. I love these videos.

[@VivaLaVittoria]

Great video. I'm currently studying to be an FNP and your content gives such great overviews of different content areas.

[@sarasims2207]

really was the best explanation i ever heard thus far ! :)

[@anacarolinacostapontes5506]

Hi!!! Greetings from Brazil! I love your videos! They are incredibly objective and accurate! I just wanted to say thank you so so much and please keep it up! Also, just a small correction: estatins are actually competitive inhibitors and not alosteric inhibitors: they bind to the active site of the enzime HMG-CoA-redutase, taking the place of the substrate HMG-CoA, as opposed to binding to the allosteric site and inducing a conformational chance of the enzime that makes the binding of the substrate to the active site impossible.

[@obeymadzingo6152]

thanks for the table at the end!

[@lauraliranzo]

WOOOOOW thank you so much! much love from DR

[@tjm1434]

Just what I needed. High-yield.

[@ekrajghai6525]

Thank you so much dirty medicine! Watching your videos makes me forget all the other resources Im using.

[@ksharma103]

Much needed!!!!

[@bitewmekonnen5862]

what an awesome explanation!!

[@ann26614]

Thank youuuu so much!!! THIS literally saved me!

[@nurula1783]

running out of things to comment in your videos but they really are helpful

[@mariamshabbir198]

Amazing Lecture!

[@professorcensored3647]

9:47 "but who cares?" cracked me up. Thank you

[@usmanwisa3386]

Excellent explanations

[@deeeeep806]

super helpful video, thank you!!

[@MedManiac1]

thank you for saving my life!! 😭😭❤️❤️

[@duocphamtruongtho4462]

Its so helpful, thanks so much!

[@garrettmorgan9926]

Thanks Dirty! Mnemonics: NPCs are Eze. LFTs are Eze. EzetimIBe Intestinal Brush border.

[@RidaZayn]

The best explanation, Thank you 👍

[@shanazannaleeguptar8075]

I used your channel and I passed pharm 1, using rn to see if i can pass pharm 2, great work sir

[@shen3998]

Amazing work dude 👍keep going

[@vietle1313]

this man the goat

[@drdianellyspintobenamaraap5935]

love this channel

[@user-vt5eg5zj1e]

Thank you very much bro. 🥰

[@JaehoonWrestling]

Your lecture is so easy to understand and ty for your contribution!!!

[@nola-baissa2433]

Great video as always. What about Thiazolidinediones?

[@Army_Dentist]

Dirty you are super clean with concepts🎉😅👏🏻

[@uzmabaig465]

Thank u so much for this video

[@jhalajayraj130]

Life saver video

[@xaaboopinkly]

Thanks sir!

[@priyam1550]

Thank you!

[@umairjaved4755]

@Dirty med my exam is next month. Kindly upload one video on Adrenergic system.
P.S: Thank u so much for every video. May God bless u for that

[@Nishamukherjee1995]

Thanks a lot sir

[@manjushreeinamdar1242]

Thankyou God sent angel

[@nasimmalakoti7031]

You're amazing

[@dream_catcher430]

Thank you very much 🙏

[@veenaveena797]

Your teaching method helps to register and retain facts...

[@alih6953]

Thanks

[@maryemmallick2752]

you promised making it easier for us and you kept your promise. KUDOS😍😇

[@moji1466]

Not the nerdy academic career 😂 ! Great video

[@25lizfair]

Thank you for the video! one thing to clarify...don't fibrates also increase HDL? via PPAR-a? the take-home points at the end only point out that niacin increases HDL, and that fibrates just reduce trigs

[@yaalia.s9033]

cant thank u enough

[@TheRebellefleur27]

thank you

[@adaezenwankwo6754]

This guy is good

[@omnasharma955]

Could you please make a video on diuretics? Thank you

[@zorrento14]

My exam is in June and I'm clenching my pearls rn

[@Kittendoc]

Same

[@HuevoBendito]

Mine's in July. We got this!

[@williamkudiewu1032]

Dirty is crazy man love this guy

[@moob2020]

Can you please upload a video about opthalmology (especially fundoscopic images )

[@sdnyanzi]

No

[@drmoctarali7385]

From somalia you are one in billion

[@Azhrxy]

So thank y dr.

[@grace_cee9335]

Thnk u so so much

[@beatriz.e.m7545]

hey just a question because you had said the Fibrates second pathway via PPAR a increases the HDL: which would mean that HDL would be increased for both Niacin and Fibrates how come you only put a decreased quantity of triglyceride in fibrates?

[@josephakalonu1052]

HDL would be increased by Niacin only.

[@lauraliranzo]

You are theeeeee besssttt!

[@ahmadcheema7198]

Thank you ^_^

[@bandanaghimire6427]

Good

[@thesweetpotatogirl]

Thnk you🌟🌟🌟

[@omerhaseebkhan]

salute to u

[@elizabethdean1209]

Thank you for your incredible generosity in the work you do! You are making the world a better place in a big way! Have you ever considered a life time membership option? I would love to support your work and my ongoing education for life. Dr. Been has the option of one time payment for unlimited access and I love the idea! ✌️ Liz Dean

[@AhsanKhan-wo2ql]

Its the mnemonic juicelord himself

[@mohannedjamal9471]

amazing, just wanted to mention that resins can increase TGs by increasing VLDL

[@johanlalnunmawia3818]

Wow ! Really 😲

[@zuhramuskan5563]

HOW?
WILL YOU MIND TO EXPLAIN IT

[@padmajahawaldar4319]

Thank you dirty ❤

[@globularfish2074]

You can use "NPCs wearing TIMs are at the IBorder" for the ezetimibe if you need a mnemonic

[@arizonablossom8635]

Thanks a lot dirty medicine🙏

[@shanemckenzie8681]

Not being mean bro, but your voice soothes me to 😴 stay awesome

[@meethamallawati850]

Please come and teach at our college

[@AN-zg3sr]

Cholestrol is not bad it's the oxidised lipids which are nd in presence of glycation..the combination results in CVD

[@nigelwang2447]

Primates bring stones to the PPARt-ay 😂

[@darkmoon3646]

DIRTY U FREAKING LEGEND

[@puneetgill4994]

💯

[@unicornspoops]

Sketchy pharm is insane for this topic. It explains the physiology but its convoluted and difficult to remember bc of that. I'd say dont bother with it and use this with FA instead.

[@graywolf2600]

Do you have a source on the dementia adverse effect?

[@DirtyMedicine]

Bottom line seems to be that FDA was concerned enough about cognitive changes. Be it statistically significant or not, it is worth knowing about imo:
link.springer.com/article/10.1007/s40264-015-0296-6
www.ahajournals.org/doi/epub/10.1161/CIRCRESAHA.118.313238

[@Angielle_]

❤❤

[@TheGhadaelarbash]

Note: PPAR-Gamma was mentioned in the insulin drugs "Bring Glitta to the party"...Glita was the drugs of TZDS and Party MoA

[@user-sb1ku5hq7h]

Love from Russia 🎉

[@joshmcgoo]

commenting for the algorithm

[@Lights0ut]

Find the odd one out
1. Atorvastatin
2. Simvastatin
3. Nystatin
4. Rosuvastatin

[@TusharMathapati.]

Nystatin because it is antifungal and others are not

[@deadricchampion6856]

Based Dirtymedicine

[@UsmleAspirantPediatrician]

What I think is that although you eat fibers so that you don’t get POOP STONES, FIBRATES make you stones 🧐

[@jamesgordon8867]

Where is Chromium?

[@sleepytraveler369]

No mention of gallstones with bile acid resins? Wtf dirty

[@kayallen7603]

statins = yuck.

[@neya732]

thank you so much dirty

[@MatanLinevitz]

Dirty, you are that guy. Thank you for contributing to all of our success!! You are a great teacher and great person in general!

[@amanydubai7880]

Thanks