What is "Click" Chemistry & Bioorthogonal Chemistry | Nobel Prize 2022

The video discusses about why Nobel Prize in Chemistry 2022 is awarded to Carolyn R. Bertozzi, Morten Meldel and K. Barry Sharpless for their development in Click Chemistry and Bioorthogonal Chemistry, what is so important and unique about. In the video we will try to understand from very simpler perspective about the complete mechanism and importance of click chemistry & bioorthogonal chemistry and how it is so useful to the humankind.
#click #chemistry #nobelprize #nobelprize2022 #clickchemistry #2022 #nobel #sharpless #bertozzi #allboutchemistry #nobellaureate #knowyourlaureate #bioorthogonal #bio #orthogonal
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[@akagordon]

The most incredible thing about Karl Barry Sharpless winning the Nobel this week isn't the work he won it for, but the fact that when he won a previous Nobel 21 years ago he spoke about what his next Nobel prize would be about.

[@Abhisheksharma17986]

im an upsc aspirant , i didnt get this topic from anywhere else , u taught it in very holistical manner . thank u so much

[@batsat11doesntbowl77]

The video and audio quality ❣️

[@spiritualseeker999]

I never thought that i could ever understand this, thanks a lot for such a clear and crisp explaination👍🏻

[@pakajni]

Explained in calm, composed manner with simplicity. Thanks a lot. :)

[@kuldeeppal4503]

Wonderful! Able to explain to a layman, with so clarity. Really commendable.

[@aspirants899]

A big thankyou to you. Was finding difficulty to understand but ur teaching make me it so simple. Power to u

[@ajay5405]

Thank you sir for presenting the whole thing so briefly and nicely ☺☺👍👍

[@prangyadas5127]

Thank you so much sir for enlightening us with your profound knowledge

[@muskansoni8872]

On point explanation and presentation 😊 now m gonna share it

[@Kumkum-ud7wg]

Waaooo Sir...😍😍👏🏻Nice explanation 👌🏻👌🏻 your way of explaining things is just awesome 🥳🥰

[@irajulsaxena]

Thanks for such an easy and detailed but relevant explanation.

[@Chemophile777]

Thank you so much for explaining. You did this previous year also with Bemjamin list and david. 🙂🙂🙂

[@deepeshmishra3811]

Thankyou for the explanation.

[@FrankGutowski-ls8jt]

KBS was just starting up as a prof at MIT when I was a grad student. He had 6 grad students at the time and was investigating organo selenium chemistry.

[@meat55]

beautiful explanation. thank you

[@poojapal5264]

Thank u sir for this informative video

[@sumagundumalla3344]

Thank you sir for your neat and clear explanation 🙂

[@callenreesespuffs]

Thank you so much for explaining so well

[@krupanidhi912]

Thanks for the nice presentation of click chemistry and Bioorthogonal chemistry. The following are the doubts.
1. Click chemistry involving copper to link azide and alkenes is fine in non biological system
2. Whereas in physiological system glycan get bound to azide. Later reactive strained alkenes may react any molecule, why alone to glycan coupled azide in a living system.
3. Does azide bind to only glycan. Does it not bind to protein or nucleic acid or lipids.
4. Is it similar to coupling a fluorescent dye or an enzyme to an antibody in ELIISA . Or real time PCR.
Pl clarify

[@thechemguy651]

From my knowledge, I can clarify the point 3 that they've done a lot of experiments and found that every time the azide only bind to glycan due to some biological specificity based on Lock & key theory.

[@tsgopalakrishnan]

Very nicely explained.. Thank you so much.

[@dyagalashalini6889]

Wonderful analysis Bhaiya 👏👏

[@SamirHusainy]

I remember seeing this 10 years ago and knew it was going to groundbreaking

[@albinxavier9709]

Thank you sir for the information ☺️

[@dikinpatel6737]

This video is a most incredible for people. Unbelievable

[@Marathisahitybama5907]

Thank you so much sir. Verybeautiful explanation, even not being science student i understood it very well.

[@bartholomewrichard3232]

Simple and excellent explanation 👏

[@rohitmondal1374]

No doubt because of awesome explanation ❣️

[@Shivachemistry99]

thank you sir for details 😌

[@pannalaldas6804]

Excellent presentation .

[@tudo3875]

Thank you for your explanation.

[@faizankhan-jp2my]

Great simple explaination sir

[@sureshphilip1280]

Good explanation sir 🙏🏻

[@govindgamara5819]

Thank you so much sir ❤️😍🙏

[@TheRxTutor]

Very well explained

[@muhammadnaveed9101]

Great sir

[@talhamashhood4103]

great💐

[@pradyutacharjee]

Great analysis

[@vishalekal7286]

Very nice explanation 👌 👍 👏

[@Mi.Ra2811]

Amazing explanation 👏👏👏

[@padmagopal684]

Excellent explained

[@shubhampanwar4230]

Great explaination

[@anjalijaiswal8445]

very nice explanation sir.

[@Krypton92546]

In my Project for MSc : RAFT polymerization of Methyl(Meth Acrylate) and Butyl Acrylate I came across this term "Click Chemistry" I think its coupling of reaction.

[@doctorsatya189]

Nice explanation 👍👍👍

[@amgamer8038]

Great 👍

[@vaishuyadav5400]

Explanation ✨👍

[@Chemistry_by_priyabrat]

Okay okay.
Esy explanation sir, thank you

[@surajitghosh6607]

Beautiful analysis sir

[@Arf.7]

Thank you Sir

[@RAMAN1909]

Quite interesting

[@palakjha6050]

Sir please make video series of all the Nobel prizes achieved till date in chemistry

[@velusubhash306]

super sir great explanation thank you

[@tamilateach5863]

Supper explanation sir 👏

[@bidhankumbhakar7771]

Thank you sir 🥰

[@srikanthp2286]

Thank you sir..

[@pallobjyoti6694]

Nice explanation🤩

[@preetidogra1847]

Thnkew sr🙂

[@vishalkeshari4237]

Thank you

[@vijaychem]

Thank you soo much sir

[@pareshpaul001]

Keep up...

[@anuradhasingh5262]

Thanks sir

[@yogi5752]

Sufex click reaction is another type of click reaction given by Sharpless team.
And they say this reaction is a sleeping beauty. Much more useful in the near future

[@kanusha2087]

Thank you sir :)

[@relaxationandmeditation663]

Good

[@abinashyadav1216]

Bhaiya Mazza aa gya ...ur awsm

[@AllBoutChemistry]

😊✌️

[@chromosome_y11]

Nice explanation brother. Chummi

[@Entertainmentplus67]

Thank you ❤️

[@GeoffryGifari]

hmmm i don't understand how combining two molecules together is different from lets say, monomers turning into polymers? is it that useful because you can stick azide and alkyne to *other* molecules that don't easily combine to get those attached?

[@ankitkumarsrivastava710]

Wonderful analysis 👏

[@AllBoutChemistry]

Thank you bhaiyya

[@academyofchemistrybyombhai1844]

proud for our department only one in India Amity institute of click chemistry and research studies

[@azadsaini1947]

Good,

[@lakshmisuryakannan8349]

Sir can u make a video about research paper publish in India

[@surbhikumari9636]

Sir on which platform u are teaching now

[@srinivaspabba7432]

Explain orthogonal concept in reaction

[@rajeswari4091]

Application plz sir for this click chemistry in other things

[@ANKITRAJPUT-kt2sw]

Is Cu+ working as a buckle same as a catalyst? Or is it being used up in the reaction?

[@AllBoutChemistry]

Acting as a catalyst

[@abinashyadav1216]

Lots of ❤️ bhaiya

[@AllBoutChemistry]

💙

[@basapuramveeresham4729]

Sir Research papers plz.

[@manzilanzelchemistry6256]

Sir eski pdf ho koi to defo

[@pritrekhabhutia-jp6fw]

After covering the cell membrane then What is the next step? I mean what is the work of that dye ? Plz reply

[@anandu_5041]

The dye tags the cell. If there's any spot that's colourless, that's the infected cell. Depending upon properties of dye or bacteria the other way around is also possible.

[@rohitmondal1374]

❣️❣️❣️❣️

[@laxmipriyabehera4621]

First view 😁

[@adityapatnaik8720]

Beautiful explanation... By the way how did you injure your finger sir

[@AllBoutChemistry]

Thank you...
Regarding finger, all thanks to my Kittens 😂

[@adityapatnaik8720]

@@AllBoutChemistry oh😅they're the naughtiest ones..

[@AllBoutChemistry]

@@adityapatnaik8720 yes 😂😂😂

[@adityapatnaik8720]

@@AllBoutChemistry and you can't scold them as they're cute ❤

[@AllBoutChemistry]

@@adityapatnaik8720 true... 😁

[@palakrajput4783]

Sir why copper 1 was used instead of copper2??

[@anandu_5041]

In the case of molecules having functional groups with oxygen, Cu2+ oxidises the groups and destroys the molecules and in bio systems, protiens are the molecules that are used in such reactions, their native structure and function gets destroyed.

[@raziquekhan1421]

Sir UOH PhD entrance admit Card kab aiga...???

[@AllBoutChemistry]

Is week

[@riddimasingh5635]

Click chemistry is not only about copper catalyst.....other metal catalyst can also be used in chemistry.....this statement is clearly wrong that click chemistry cannot be used in biological system... I myself doing my PhD in click chemistry

[@studywithease3995]

Hey can u help me to know click chemistry?

[@anandu_5041]

He never said click cannot be used in bio systems plus he never said click is about Cu catalyst.

[@tanbinshakibsabab3797]

🤍🩵

[@jitendhobi8945]

Sir hindi mai bhi bol sakta ho na

[@RahulSingh-cb2jm]

BHAI HINDI ME BOLO

[@anjandeep9415]

Well explained

[@EthelNaboti]

Thank you

[@Babunaik5508]

Thank you sir 😍

[@afrinahamed6653]

Thank you sir

[@anitarathod1285]

Thank you sir